celastrol has been researched along with Alzheimer Disease in 4 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 3 (75.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hao, J; Li, J | 1 |
| Ethiraj, P; Natarajan, S; Samuel, S; Veerappan, K; Vetrivel, U | 1 |
| Ait-Ghezala, G; Bachmeier, C; Beaulieu-Abdelahad, D; Ganey, NJ; Laporte, V; March, A; Mullan, MJ; Paris, D; Patel, NS | 1 |
| Allison, AC; Alvarez, XA; Cacabelos, R; Lombardi, VR; Vigo, C | 1 |
2 review(s) available for celastrol and Alzheimer Disease
| Article | Year |
|---|---|
Treatment of Neurodegenerative Diseases with Bioactive Components of
Topics: Alzheimer Disease; Animals; Diterpenes; Epoxy Compounds; Humans; Medicine, Chinese Traditional; Molecular Conformation; Neurodegenerative Diseases; Neuroprotective Agents; Parkinson Disease; Pentacyclic Triterpenes; Phenanthrenes; Phytotherapy; Tripterygium; Triterpenes | 2019 |
Celastrol, a potent antioxidant and anti-inflammatory drug, as a possible treatment for Alzheimer's disease.
Topics: Alzheimer Disease; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Humans; Pentacyclic Triterpenes; Triterpenes | 2001 |
2 other study(ies) available for celastrol and Alzheimer Disease
| Article | Year |
|---|---|
Inhibition of IKKβ by celastrol and its analogues - an in silico and in vitro approach.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Anti-Inflammatory Agents; Binding Sites; Cell Line, Tumor; Humans; Hydrogen Bonding; I-kappa B Kinase; Molecular Docking Simulation; Neurons; Neuroprotective Agents; Pentacyclic Triterpenes; Peptide Fragments; Phosphorylation; Protein Binding; Protein Conformation; Protein Kinase Inhibitors; Signal Transduction; Structure-Activity Relationship; Tretinoin; Triterpenes | 2017 |
Reduction of beta-amyloid pathology by celastrol in a transgenic mouse model of Alzheimer's disease.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Amyloid Precursor Protein Secretases; Analysis of Variance; Animals; Aspartic Acid Endopeptidases; Brain; Carcinogens; Cell Cycle Proteins; Cell Line, Transformed; Cricetinae; Cricetulus; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; HSP90 Heat-Shock Proteins; Humans; Mice; Mice, Transgenic; Molecular Chaperones; Pentacyclic Triterpenes; Phorbol Esters; Presenilin-1; Signal Transduction; Transfection; Triterpenes | 2010 |