Page last updated: 2024-09-03

celastrol and Alzheimer Disease

celastrol has been researched along with Alzheimer Disease in 4 studies

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (25.00)29.6817
2010's3 (75.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hao, J; Li, J1
Ethiraj, P; Natarajan, S; Samuel, S; Veerappan, K; Vetrivel, U1
Ait-Ghezala, G; Bachmeier, C; Beaulieu-Abdelahad, D; Ganey, NJ; Laporte, V; March, A; Mullan, MJ; Paris, D; Patel, NS1
Allison, AC; Alvarez, XA; Cacabelos, R; Lombardi, VR; Vigo, C1

Reviews

2 review(s) available for celastrol and Alzheimer Disease

ArticleYear
Treatment of Neurodegenerative Diseases with Bioactive Components of
    The American journal of Chinese medicine, 2019, Volume: 47, Issue:4

    Topics: Alzheimer Disease; Animals; Diterpenes; Epoxy Compounds; Humans; Medicine, Chinese Traditional; Molecular Conformation; Neurodegenerative Diseases; Neuroprotective Agents; Parkinson Disease; Pentacyclic Triterpenes; Phenanthrenes; Phytotherapy; Tripterygium; Triterpenes

2019
Celastrol, a potent antioxidant and anti-inflammatory drug, as a possible treatment for Alzheimer's disease.
    Progress in neuro-psychopharmacology & biological psychiatry, 2001, Volume: 25, Issue:7

    Topics: Alzheimer Disease; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Humans; Pentacyclic Triterpenes; Triterpenes

2001

Other Studies

2 other study(ies) available for celastrol and Alzheimer Disease

ArticleYear
Inhibition of IKKβ by celastrol and its analogues - an in silico and in vitro approach.
    Pharmaceutical biology, 2017, Volume: 55, Issue:1

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Anti-Inflammatory Agents; Binding Sites; Cell Line, Tumor; Humans; Hydrogen Bonding; I-kappa B Kinase; Molecular Docking Simulation; Neurons; Neuroprotective Agents; Pentacyclic Triterpenes; Peptide Fragments; Phosphorylation; Protein Binding; Protein Conformation; Protein Kinase Inhibitors; Signal Transduction; Structure-Activity Relationship; Tretinoin; Triterpenes

2017
Reduction of beta-amyloid pathology by celastrol in a transgenic mouse model of Alzheimer's disease.
    Journal of neuroinflammation, 2010, Mar-08, Volume: 7

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Amyloid Precursor Protein Secretases; Analysis of Variance; Animals; Aspartic Acid Endopeptidases; Brain; Carcinogens; Cell Cycle Proteins; Cell Line, Transformed; Cricetinae; Cricetulus; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; HSP90 Heat-Shock Proteins; Humans; Mice; Mice, Transgenic; Molecular Chaperones; Pentacyclic Triterpenes; Phorbol Esters; Presenilin-1; Signal Transduction; Transfection; Triterpenes

2010