cefuzonam and Otitis-Media

cefuzonam has been researched along with Otitis-Media* in 2 studies

Other Studies

2 other study(ies) available for cefuzonam and Otitis-Media

Article	Year
Gradenigo's syndrome: CT and MRI findings. Pediatric radiology, 1996, Volume: 26, Issue:9 We report the case of an 8-year-old girl with Gradenigo's syndrome. Involvement of the petrous portion of the left temporal bone was demonstrated by CT and an inflammatory lesion of the left petrous apex was clearly shown by MRI, which is useful in diagnosis and management of apical petrositis. Topics: Abducens Nerve; Ceftizoxime; Cephalosporins; Child; Contrast Media; Cranial Nerve Diseases; Female; Gadolinium; Gadolinium DTPA; Humans; Magnetic Resonance Imaging; Mastoid; Mastoiditis; Organometallic Compounds; Otitis Media; Paralysis; Penicillins; Pentetic Acid; Petrous Bone; Piperacillin; Syndrome; Tomography, X-Ray Computed	1996
Tissue transmigration of CZON (Cosmosin) to middle ear mucosa, maxillary sinus mucosa, and palatine tonsils. Auris, nasus, larynx, 1994, Volume: 21, Issue:4 The concentration of CZON was determined by HPLC in surgical patients with chronic otitis media, sinusitis, and tonsillitis. One gram of CZON was injected intravenously prior to surgery. The time course of the mean tissue CZON level was as follows: In the middle ear mucosa, 3.7 micrograms/g at 15 min, 7.2 micrograms/g at 30 min, and 2.9 micrograms/g at 1 hr (the half life: 21.3 min). In the maxillary sinus mucosa, 10.5 micrograms/g at 15 min, 11.8 micrograms/g at 30 min, and 2.8 micrograms/g at 1 hr (the half life: 17.5 min). In the tonsils, 14.9 micrograms/g at 15 min, 9.3 micrograms/g at 30 min, and 2.0 micrograms/g at 1 hr (the half life: 13.2 min). The concentration was high in the maxillary sinus mucosa and the tonsils, but was low in the middle ear mucosa. In the formers the transfer ratio reached its peak 15 to 30 min after administration, but in the latter the peak was reached 30 to 60 min after administration. The order of the transfer ratio at each region was above 25%. The tissue concentration exceeded the MIC80s of frequent isolates from these infections. CZON is considered to be a highly useful drug in the treatment of these infections. Topics: Adolescent; Adult; Ceftizoxime; Child; Ear, Middle; Female; Humans; Injections, Intravenous; Male; Maxillary Sinus; Middle Aged; Mucous Membrane; Nasal Mucosa; Otitis Media; Sinusitis; Staphylococcus aureus; Tissue Distribution; Tonsillitis	1994

Article

Year

Gradenigo's syndrome: CT and MRI findings.

Pediatric radiology, 1996, Volume: 26, Issue:9

We report the case of an 8-year-old girl with Gradenigo's syndrome. Involvement of the petrous portion of the left temporal bone was demonstrated by CT and an inflammatory lesion of the left petrous apex was clearly shown by MRI, which is useful in diagnosis and management of apical petrositis.

Topics: Abducens Nerve; Ceftizoxime; Cephalosporins; Child; Contrast Media; Cranial Nerve Diseases; Female; Gadolinium; Gadolinium DTPA; Humans; Magnetic Resonance Imaging; Mastoid; Mastoiditis; Organometallic Compounds; Otitis Media; Paralysis; Penicillins; Pentetic Acid; Petrous Bone; Piperacillin; Syndrome; Tomography, X-Ray Computed

1996

Tissue transmigration of CZON (Cosmosin) to middle ear mucosa, maxillary sinus mucosa, and palatine tonsils.

Auris, nasus, larynx, 1994, Volume: 21, Issue:4

The concentration of CZON was determined by HPLC in surgical patients with chronic otitis media, sinusitis, and tonsillitis. One gram of CZON was injected intravenously prior to surgery. The time course of the mean tissue CZON level was as follows: In the middle ear mucosa, 3.7 micrograms/g at 15 min, 7.2 micrograms/g at 30 min, and 2.9 micrograms/g at 1 hr (the half life: 21.3 min). In the maxillary sinus mucosa, 10.5 micrograms/g at 15 min, 11.8 micrograms/g at 30 min, and 2.8 micrograms/g at 1 hr (the half life: 17.5 min). In the tonsils, 14.9 micrograms/g at 15 min, 9.3 micrograms/g at 30 min, and 2.0 micrograms/g at 1 hr (the half life: 13.2 min). The concentration was high in the maxillary sinus mucosa and the tonsils, but was low in the middle ear mucosa. In the formers the transfer ratio reached its peak 15 to 30 min after administration, but in the latter the peak was reached 30 to 60 min after administration. The order of the transfer ratio at each region was above 25%. The tissue concentration exceeded the MIC80s of frequent isolates from these infections. CZON is considered to be a highly useful drug in the treatment of these infections.

Topics: Adolescent; Adult; Ceftizoxime; Child; Ear, Middle; Female; Humans; Injections, Intravenous; Male; Maxillary Sinus; Middle Aged; Mucous Membrane; Nasal Mucosa; Otitis Media; Sinusitis; Staphylococcus aureus; Tissue Distribution; Tonsillitis

1994