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cefuroxime and Pneumonia, Pneumococcal

cefuroxime has been researched along with Pneumonia, Pneumococcal in 19 studies

Cefuroxime: Broad-spectrum cephalosporin antibiotic resistant to beta-lactamase. It has been proposed for infections with gram-negative and gram-positive organisms, GONORRHEA, and HAEMOPHILUS.
cefuroxime : A 3-(carbamoyloxymethyl)cephalosporin compound having a 7-(2Z)-2-(furan-2-yl)-2-(methoxyimino)acetamido side chain.

Pneumonia, Pneumococcal: A febrile disease caused by STREPTOCOCCUS PNEUMONIAE.

Research Excerpts

ExcerptRelevanceReference
"The clinical and microbiological efficacy, as well as the tolerability of the amoxicillin/sulbactam combination as empiric treatment for complicated community-acquired pneumonia (CCAP) were evaluated in children from 3 months to 15 years with CCAP who were randomized 1:1 to receive either amoxicillin/sulbactam or cefuroxime."9.11Treatment of childhood complicated community-acquired pneumonia with amoxicillin/sulbactam. ( Arbo, A; Lovera, D, 2005)
"A regimen of cefprozil (500 mg twice daily), a new oral cephalosporin with a broad in vitro spectrum of antimicrobial activity, was compared to standard regimens of cefaclor (500 mg three times daily), cefuroxime axetil (500 mg twice daily), or amoxicillin/clavulanate (500 mg/125 mg three times daily) for the treatment of lower respiratory tract infections (mainly bronchitis and acute exacerbations of chronic bronchitis) in adults in three open-label, randomized trials."6.17Review of the experience with cefprozil for the treatment of lower respiratory tract infections. ( Pelletier, LL, 1992)
"Cefuroxime axetil is an oral cephalosporin with proven efficacy in adult lower respiratory tract infections."5.29[Treatment of bacterial pneumonias with cefuroxime-axetil. Predictive value of measurement of the in vitro susceptibility]. ( Cluzel, R; Modaï, J; Portier, H, 1996)
"The clinical and microbiological efficacy, as well as the tolerability of the amoxicillin/sulbactam combination as empiric treatment for complicated community-acquired pneumonia (CCAP) were evaluated in children from 3 months to 15 years with CCAP who were randomized 1:1 to receive either amoxicillin/sulbactam or cefuroxime."5.11Treatment of childhood complicated community-acquired pneumonia with amoxicillin/sulbactam. ( Arbo, A; Lovera, D, 2005)
" We report a toddler who had breakthrough bacteremia and meningitis develop because of drug-resistant pneumococcus while receiving treatment with cefotaxime and cefuroxime for pneumonia."3.70Breakthrough bacteremia and meningitis during treatment with cephalosporins parenterally for pneumococcal pneumonia. ( Brown, SP; Buckingham, SC; Joaquin, VH, 1998)
"The therapeutic activity of FCE 22891 was compared with that of two new oral cephalosporins, cefuroxime axetil and cefixime against Streptococcus pneumoniae respiratory infection and subcutaneous abscesses induced by mixed aerobes and anaerobes in mice."3.67Activity of FCE 22891 compared with cefuroxime axetil and cefixime in pulmonary and subcutaneous infections in mice. ( Castellani, P; Della Bruna, C; Rossi, R; Younes, G, 1989)
"Levofloxacin is a new fluoroquinolone active against S."2.69[Levofloxacin in the treatment of community-acquired pneumococcal pneumonia]. ( Léophonte, P; Veyssier, P, 1999)
"Cefuroxime was given by i."2.67Cefuroxime efficacy in pneumonia: sequential short-course i.v./oral suspension therapy. ( Cuningham, K; Dagan, R; Engelhard, D; Ephros, M; Shalit, I, 1994)
"Infants and children with pneumococcal infections cared for at eight children's hospitals."1.31Outcome of invasive infections outside the central nervous system caused by Streptococcus pneumoniae isolates nonsusceptible to ceftriazone in children treated with beta-lactam antibiotics. ( Barson, WJ; Bradley, JS; Givner, LB; Kaplan, SL; Kim, KS; Mason, EO; Schutze, GE; Tan, TQ; Wald, ER; Yogev, R, 2001)
"Cefuroxime axetil is an oral cephalosporin with proven efficacy in adult lower respiratory tract infections."1.29[Treatment of bacterial pneumonias with cefuroxime-axetil. Predictive value of measurement of the in vitro susceptibility]. ( Cluzel, R; Modaï, J; Portier, H, 1996)
"Vancomycin was the most effective in vivo as measured by the 50% effective dose (ED50) after single doses 1 h post-inoculation."1.27The pneumococcus and the mouse-protection test: correlation of in vitro and in vivo activity for beta-lactam antibiotics, vancomycin, erythromycin and gentamicin. ( Frimodt-Møller, N; Thomsen, VF, 1987)

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-19902 (10.53)18.7374
1990's11 (57.89)18.2507
2000's5 (26.32)29.6817
2010's1 (5.26)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Yayan, J1
Ghebremedhin, B1
Rasche, K1
Wiener-Well, Y1
Raveh, D1
Schlesinger, Y1
Yinnon, AM1
Rudensky, B1
Lode, H1
File, TM1
Mandell, L1
Ball, P1
Pypstra, R1
Thomas, M1
Lovera, D1
Arbo, A1
Shalit, I1
Dagan, R1
Engelhard, D1
Ephros, M1
Cuningham, K1
Caballero-Granado, FJ1
Palomino-Nicás, J1
Pachón, J1
García-Curiel, A1
Cluzel, R1
Portier, H1
Modaï, J1
Verhaegen, J1
Vandeven, J1
Verbiest, N1
Fossion, M1
Mengeot, PM1
Amougou, M1
Verbist, L1
Buckingham, SC1
Brown, SP1
Joaquin, VH1
Tan, TQ2
Mason, EO2
Barson, WJ2
Wald, ER2
Schutze, GE2
Bradley, JS2
Arditi, M1
Givner, LB2
Yogev, R2
Kim, KS2
Kaplan, SL2
Dowell, SF1
Smith, T1
Leversedge, K1
Snitzer, J1
Léophonte, P1
Veyssier, P1
Calvo, A1
Amores, R1
Valero, E1
Sevillano, D1
Prieto, J1
Singh, KP1
Voolmann, T1
Lang, SD1
Pelletier, LL1
Zamotaev, IP1
Sokolova, VI1
Kamnev, IuV1
Bormotova, MS1
Rossi, R1
Castellani, P1
Younes, G1
Della Bruna, C1
Frimodt-Møller, N1
Thomsen, VF1

Reviews

1 review available for cefuroxime and Pneumonia, Pneumococcal

ArticleYear
Review of the experience with cefprozil for the treatment of lower respiratory tract infections.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 1992, Volume: 14 Suppl 2

    Topics: Acute Disease; Amoxicillin; Amoxicillin-Potassium Clavulanate Combination; Bronchitis; Bronchopneumo

1992

Trials

5 trials available for cefuroxime and Pneumonia, Pneumococcal

ArticleYear
Oral gemifloxacin versus sequential therapy with intravenous ceftriaxone/oral cefuroxime with or without a macrolide in the treatment of patients hospitalized with community-acquired pneumonia: a randomized, open-label, multicenter study of clinical effic
    Clinical therapeutics, 2002, Volume: 24, Issue:11

    Topics: Administration, Oral; Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Anti-Infect

2002
Treatment of childhood complicated community-acquired pneumonia with amoxicillin/sulbactam.
    Journal of chemotherapy (Florence, Italy), 2005, Volume: 17, Issue:3

    Topics: Adolescent; Amoxicillin; Anti-Bacterial Agents; Cefuroxime; Child; Child, Preschool; Community-Acqui

2005
Cefuroxime efficacy in pneumonia: sequential short-course i.v./oral suspension therapy.
    Israel journal of medical sciences, 1994, Volume: 30, Issue:9

    Topics: Acute Disease; Administration, Oral; Cefuroxime; Child, Preschool; Community-Acquired Infections; Dr

1994
[Levofloxacin in the treatment of community-acquired pneumococcal pneumonia].
    Presse medicale (Paris, France : 1983), 1999, Nov-20, Volume: 28, Issue:36

    Topics: Adult; Aged; Amoxicillin; Anti-Infective Agents; Ceftriaxone; Cefuroxime; Clavulanic Acid; Community

1999
Review of the experience with cefprozil for the treatment of lower respiratory tract infections.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 1992, Volume: 14 Suppl 2

    Topics: Acute Disease; Amoxicillin; Amoxicillin-Potassium Clavulanate Combination; Bronchitis; Bronchopneumo

1992

Other Studies

14 other studies available for cefuroxime and Pneumonia, Pneumococcal

ArticleYear
No Resistance to Penicillin, Cefuroxime, Cefotaxime, or Vancomycin in Pneumococcal Pneumonia.
    International journal of medical sciences, 2015, Volume: 12, Issue:12

    Topics: Aged; Cefotaxime; Cefuroxime; Cephalosporin Resistance; Cross Infection; Drug Resistance, Bacterial;

2015
Cefuroxime for empiric treatment of community-acquired pneumococcal pneumonia: is there a generation gap?
    Chemotherapy, 2009, Volume: 55, Issue:2

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Case-Control Studies; Cefuroxime;

2009
Cefuroxime efficacy in treatment of bacteremic pneumonia due to penicillin-resistant and cefuroxime-resistant Streptococcus pneumoniae.
    Antimicrobial agents and chemotherapy, 1996, Volume: 40, Issue:5

    Topics: Adolescent; Aged; Cefuroxime; Cephalosporins; Dose-Response Relationship, Drug; Humans; Male; Middle

1996
[Treatment of bacterial pneumonias with cefuroxime-axetil. Predictive value of measurement of the in vitro susceptibility].
    Pathologie-biologie, 1996, Volume: 44, Issue:3

    Topics: Adolescent; Adult; Aged; Cefuroxime; Cephalosporins; Female; Haemophilus influenzae; Humans; Male; M

1996
Impredictable susceptibility for cephalosporins in penicillin resistant Streptococcus pneumoniae.
    Acta clinica Belgica, 1997, Volume: 52, Issue:2

    Topics: Aged; Aged, 80 and over; Anti-Bacterial Agents; Ceftriaxone; Cefuroxime; Cephalosporin Resistance; C

1997
Breakthrough bacteremia and meningitis during treatment with cephalosporins parenterally for pneumococcal pneumonia.
    The Journal of pediatrics, 1998, Volume: 132, Issue:1

    Topics: Bacteremia; Cefotaxime; Cefuroxime; Cephalosporin Resistance; Cephalosporins; Drug Resistance, Multi

1998
Clinical characteristics and outcome of children with pneumonia attributable to penicillin-susceptible and penicillin-nonsusceptible Streptococcus pneumoniae.
    Pediatrics, 1998, Volume: 102, Issue:6

    Topics: Adolescent; Adult; Ambulatory Care; Anti-Bacterial Agents; Ceftriaxone; Cefuroxime; Cephalosporins;

1998
Failure of treatment of pneumonia associated with highly resistant pneumococci in a child.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 1999, Volume: 29, Issue:2

    Topics: Anti-Bacterial Agents; beta-Lactam Resistance; Cefotaxime; Cefuroxime; Cephalosporins; Drug Therapy,

1999
Outcome of invasive infections outside the central nervous system caused by Streptococcus pneumoniae isolates nonsusceptible to ceftriazone in children treated with beta-lactam antibiotics.
    The Pediatric infectious disease journal, 2001, Volume: 20, Issue:4

    Topics: Anti-Bacterial Agents; Bacteremia; Cefotaxime; Ceftriaxone; Cefuroxime; Cephalosporin Resistance; Ce

2001
[Activity of different antimicrobial agents against penicillin-resistant Streptococcus pneumoniae].
    Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia, 2001, Volume: 14, Issue:4

    Topics: Amoxicillin; Anti-Bacterial Agents; Azithromycin; Cefaclor; Cefixime; Cefpodoxime; Ceftibuten; Cefti

2001
Pneumococcal bacteraemia in south Auckland: a five year review with emphasis on prescribing practices.
    The New Zealand medical journal, 1992, Oct-14, Volume: 105, Issue:943

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amoxicillin; Anti-Bacterial Agents; Bacteremia; Cefuroxi

1992
[A case of successful antibiotic therapy of legionnaires' disease with lesions of the lungs and heart].
    Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic], 1990, Volume: 35, Issue:6

    Topics: Atrial Fibrillation; Cefuroxime; Cephalosporins; Digoxin; Drug Therapy, Combination; Female; Humans;

1990
Activity of FCE 22891 compared with cefuroxime axetil and cefixime in pulmonary and subcutaneous infections in mice.
    The Journal of antimicrobial chemotherapy, 1989, Volume: 23 Suppl C

    Topics: Abscess; Animals; Anti-Bacterial Agents; Bacterial Infections; Bacteroides fragilis; Bacteroides Inf

1989
The pneumococcus and the mouse-protection test: correlation of in vitro and in vivo activity for beta-lactam antibiotics, vancomycin, erythromycin and gentamicin.
    Acta pathologica, microbiologica, et immunologica Scandinavica. Section B, Microbiology, 1987, Volume: 95, Issue:3

    Topics: Animals; Anti-Bacterial Agents; Cefuroxime; Dose-Response Relationship, Drug; Erythromycin; Gentamic

1987