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cefuroxime and Pneumococcal Infections

cefuroxime has been researched along with Pneumococcal Infections in 36 studies

Cefuroxime: Broad-spectrum cephalosporin antibiotic resistant to beta-lactamase. It has been proposed for infections with gram-negative and gram-positive organisms, GONORRHEA, and HAEMOPHILUS.
cefuroxime : A 3-(carbamoyloxymethyl)cephalosporin compound having a 7-(2Z)-2-(furan-2-yl)-2-(methoxyimino)acetamido side chain.

Pneumococcal Infections: Infections with bacteria of the species STREPTOCOCCUS PNEUMONIAE.

Research Excerpts

ExcerptRelevanceReference
"The bacteriological eradication rates of Streptococcus pneumoniae from sputum of patients experiencing acute exacerbations of chronic bronchitis (WHO definition) have been compared following therapy with either cefuroxime axetil 250 mg b."9.09Bacteriological eradication of Streptococcus pneumoniae from patients with acute exacerbations of chronic bronchitis: cefuroxime axetil versus cefixime. ( Geslin, P; Leblanc, F; Petitpretz, P; Rio, Y; Zuck, P, 1999)
"The comparative efficacies of amoxicillin and cefuroxime against acute otitis media caused by a penicillin-resistant (MIC, 2 micrograms/ml) Streptococcus pneumoniae strain were assessed in a gerbil model by challenging each ear with 10(7) bacteria through transbullar instillation."7.70In vivo efficacies of amoxicillin and cefuroxime against penicillin-resistant Streptococcus pneumoniae in a gerbil model of acute otitis media. ( Aguilar, L; Cenjor, C; García-Calvo, G; Giménez, MJ; Nieto, E; Parra, A; Ponte, C; Soriano, F, 1998)
"Amoxicillin, cefpodoxime and cefuroxime MICs remained low against numerous penicillin resistant strains, indicating that these three oral antibiotics (in combination with clavulanate for amoxicillin) have a useful potential for the treatment of acute otitis media when risk factors for pneumococcal penicillin-resistant infections are detected."7.70[Development of resistance to beta-lactams and other antibiotics of pneumococci isolated from acute otitis media in France: statement of the National Reference Center 1995-1996]. ( Fremaux, A; Georges, S; Geslin, P; Sissia, G; Spicq, C, 1998)
"The bacteriological eradication rates of Streptococcus pneumoniae from sputum of patients experiencing acute exacerbations of chronic bronchitis (WHO definition) have been compared following therapy with either cefuroxime axetil 250 mg b."5.09Bacteriological eradication of Streptococcus pneumoniae from patients with acute exacerbations of chronic bronchitis: cefuroxime axetil versus cefixime. ( Geslin, P; Leblanc, F; Petitpretz, P; Rio, Y; Zuck, P, 1999)
"A series of patients aged 3 months to 15 years who fulfilled strict criteria for bacterial pneumonia, other respiratory infections, sepsis-like infections, and other acute infections were prospectively randomized to receive parenteral penicillin or cefuroxime randomly for 4 or 7 days."5.09Successful shortening from seven to four days of parenteral beta-lactam treatment for common childhood infections: a prospective and randomized study. ( Kallio, MJ; Peltola, H; Vuori-Holopainen, E, 2001)
" pneumoniae is associated with an impaired bacteriologic and clinical response of acute otitis media to cefaclor and cefuroxime axetil."5.08Impaired bacteriologic response to oral cephalosporins in acute otitis media caused by pneumococci with intermediate resistance to penicillin. ( Abramson, O; Dagan, R; Fliss, DM; Goshen, S; Greenberg, D; Lang, R; Leiberman, A; Leibovitz, E; Yagupsky, P, 1996)
"The comparative efficacies of amoxicillin and cefuroxime against acute otitis media caused by a penicillin-resistant (MIC, 2 micrograms/ml) Streptococcus pneumoniae strain were assessed in a gerbil model by challenging each ear with 10(7) bacteria through transbullar instillation."3.70In vivo efficacies of amoxicillin and cefuroxime against penicillin-resistant Streptococcus pneumoniae in a gerbil model of acute otitis media. ( Aguilar, L; Cenjor, C; García-Calvo, G; Giménez, MJ; Nieto, E; Parra, A; Ponte, C; Soriano, F, 1998)
"Amoxicillin, cefpodoxime and cefuroxime MICs remained low against numerous penicillin resistant strains, indicating that these three oral antibiotics (in combination with clavulanate for amoxicillin) have a useful potential for the treatment of acute otitis media when risk factors for pneumococcal penicillin-resistant infections are detected."3.70[Development of resistance to beta-lactams and other antibiotics of pneumococci isolated from acute otitis media in France: statement of the National Reference Center 1995-1996]. ( Fremaux, A; Georges, S; Geslin, P; Sissia, G; Spicq, C, 1998)
"The efficacy of amoxicillin/clavulanate and cefuroxime was determined in a gerbil model of otitis media with a mixed Streptococcus pneumoniae plus Haemophilus influenzae middle ear (ME) infection."3.70Role of Streptococcus pneumoniae and Haemophilus influenzae in the development of acute otitis media and otitis media with effusion in a gerbil model. ( Aguilar, L; Cenjor, C; García-Calvo, G; Giménez, MJ; Nieto, E; Parra, A; Ponte, C; Soriano, F, 2000)
"Eighty-four children suffering from acute otitis media caused by Streptococcus pneumoniae were treated prospectively with cefuroxime axetil suspension (30 mg/kg of body weight twice daily for 8 days)."3.69In vivo correlates for Streptococcus pneumoniae penicillin resistance in acute otitis media. ( Berche, P; Gehanno, P; Lenoir, G, 1995)
"The antimicrobial spectrum of cefuroxime, an antibiotic of the cephalosporin family was studied in vitro with respect to 11 species (16 strains) of gram-positive and gram-negative bacteria and in vivo on albino mice with experimental salmonellosis or pneumococcal infections."3.66[Experimental study of the antibiotic activity of cefuroxime]. ( Bil'ko, IP; Ginzburg, TS; Mil'chenko, KP; Sokalo, SV, 1982)
" The population was characterized by a population pharmacokinetic model, and distributions of CLcr and body weight were reflective of the target group."1.35Estimation of cefuroxime dosage using pharmacodynamic targets, MIC distributions, and minimization of a risk function. ( Cars, O; Jönsson, S; Karlsson, MO; Viberg, A, 2008)
"Infants and children with pneumococcal infections cared for at eight children's hospitals."1.31Outcome of invasive infections outside the central nervous system caused by Streptococcus pneumoniae isolates nonsusceptible to ceftriazone in children treated with beta-lactam antibiotics. ( Barson, WJ; Bradley, JS; Givner, LB; Kaplan, SL; Kim, KS; Mason, EO; Schutze, GE; Tan, TQ; Wald, ER; Yogev, R, 2001)
"Amoxicillin was by far the most effective antibiotic when considering its intrinsic activity (96% of the PRSP inhibited at 2 mg/l), the inhibitory quotient (100% of the PRSP > 1 vs 69."1.30Choice of an oral beta-lactam antibiotic for infections due to penicillin-resistant Streptococcus pneumoniae. ( Goldstein, FW, 1997)
"Ampicillin + gentamicin was significantly superior to gentamicin alone but not to ampicillin alone."1.27Interaction between beta-lactam antibiotics and gentamicin against Streptococcus pneumoniae in vitro and in vivo. ( Frimodt-Møller, N; Frølund Thomsen, V, 1987)
"Treatment with cefuroxime appears to be a safe and effective therapy for pediatric soft-tissue infections due to H influenzae and S pneumoniae."1.27Cefuroxime therapy for bacteremic soft-tissue infections in children. ( Barson, WJ; Brady, MT; Hribar, MM; Marcon, MJ; Miller, MA; Pacini, DL; Powell, DA, 1985)

Research

Studies (36)

TimeframeStudies, this research(%)All Research%
pre-19905 (13.89)18.7374
1990's16 (44.44)18.2507
2000's10 (27.78)29.6817
2010's3 (8.33)24.3611
2020's2 (5.56)2.80

Authors

AuthorsStudies
Gamil, A1
Chokephaibulkit, K1
Phongsamart, W1
Techasaensiri, C1
Piralam, B1
Thamaree, R1
Chen, KJ1
Chong, YJ1
Sun, MH1
Chen, HC1
Liu, L1
Chen, YP1
Wu, WC1
Kang, EY1
Lai, CC1
Torumkuney, D1
Zemlickova, H1
Maruscak, M1
Morrissey, I1
Al-Mazrou, KA1
Shibl, AM2
Kandeil, W1
Pirçon, JY1
Marano, C1
Burton, C1
Walls, T1
Price, N1
Glasgow, T1
Walker, C1
Beasley, S1
Best, E1
Viberg, A1
Cars, O1
Karlsson, MO1
Jönsson, S1
Neuhauser, MM1
Prause, JL1
Danziger, LH1
Pendland, SL1
Marrie, TJ1
Peltola, V1
Svedström, E1
Waris, M1
Heikkinen, T1
Ruuskanen, O1
Bil'ko, IP1
Mil'chenko, KP1
Ginzburg, TS1
Sokalo, SV1
Gehanno, P1
Lenoir, G1
Berche, P1
Lopardo, HA1
Lovadina, L1
Rubeglio, EA1
Krisher, KK1
Linscott, A1
Paniara, O1
Platsouka, E1
Dimopoulou, H1
Constantoulaki, S1
Skedros, DG1
Haddad, J1
Bluestone, CD1
Curtin, HD1
Dagan, R1
Abramson, O1
Leibovitz, E1
Lang, R1
Goshen, S1
Greenberg, D1
Yagupsky, P1
Leiberman, A1
Fliss, DM1
Waites, K1
Swiatlo, E1
Gray, B1
Brookings, E1
Goldstein, FW1
Verhaegen, J1
Verbist, L1
Cenjor, C2
Ponte, C2
Parra, A2
Nieto, E2
García-Calvo, G2
Giménez, MJ3
Aguilar, L4
Soriano, F2
Geslin, P2
Fremaux, A1
Sissia, G1
Spicq, C1
Georges, S1
Lontie, M1
Liekens, K1
Deschilder, I1
Baquero, F1
García-Rodríguez, JA1
García de Lomas, J1
Williams-Bouyer, N1
Hernandez, A1
Reisner, BS1
Zuck, P1
Petitpretz, P1
Rio, Y1
Leblanc, F1
Al Rasheed, AM1
Elbashier, AM1
Osoba, AO1
Oliver, A1
Sabán, J1
Pujol, I1
Peromingo, R1
Tarragó, D1
Galindo, J1
Meseguer, MA1
Peltola, H1
Vuori-Holopainen, E1
Kallio, MJ1
Pérez-Trallero, E1
Alkorta, M1
Vicente, D1
Kaplan, SL1
Mason, EO1
Barson, WJ2
Tan, TQ1
Schutze, GE1
Bradley, JS1
Givner, LB1
Kim, KS1
Yogev, R1
Wald, ER1
Singh, KP1
Voolmann, T1
Lang, SD1
Henderson, FW1
Gilligan, PH1
Wait, K1
Goff, DA1
Frimodt-Møller, N2
Frølund Thomsen, V1
Bentzon, MW1
Thomsen, VF1
Miller, MA1
Marcon, MJ1
Hribar, MM1
Brady, MT1
Pacini, DL1
Powell, DA1

Reviews

1 review available for cefuroxime and Pneumococcal Infections

ArticleYear
Pneumococcal disease in Thailand.
    International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases, 2021, Volume: 102

    Topics: Anti-Bacterial Agents; Cefuroxime; Cost of Illness; Cost-Benefit Analysis; Drug Resistance, Multiple

2021

Trials

4 trials available for cefuroxime and Pneumococcal Infections

ArticleYear
Experience with levofloxacin in a critical pathway for the treatment of community-acquired pneumonia.
    Chemotherapy, 2004, Volume: 50 Suppl 1

    Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Ambulatory Care; Anti-Infective Agents; Azi

2004
Impaired bacteriologic response to oral cephalosporins in acute otitis media caused by pneumococci with intermediate resistance to penicillin.
    The Pediatric infectious disease journal, 1996, Volume: 15, Issue:11

    Topics: Acute Disease; Administration, Oral; Cefaclor; Cefuroxime; Cephalosporins; Child, Preschool; Drug Re

1996
Bacteriological eradication of Streptococcus pneumoniae from patients with acute exacerbations of chronic bronchitis: cefuroxime axetil versus cefixime.
    International journal of clinical practice, 1999, Volume: 53, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Bronchitis; Cefixime; Cefuroxime; Cephalosporins; Chronic Disease; D

1999
Successful shortening from seven to four days of parenteral beta-lactam treatment for common childhood infections: a prospective and randomized study.
    International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases, 2001, Volume: 5, Issue:1

    Topics: Adolescent; Bacterial Infections; Cefuroxime; Child; Child, Preschool; Female; Humans; Infant; Male;

2001

Other Studies

31 other studies available for cefuroxime and Pneumococcal Infections

ArticleYear
Streptococcus pneumoniae endophthalmitis: clinical settings, antibiotic susceptibility, and visual outcomes.
    Scientific reports, 2021, 03-18, Volume: 11, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Cataract; Cataract Extraction; Ceftriaxone; C

2021
Results from the Survey of Antibiotic Resistance (SOAR) 2014-16 in the Czech Republic.
    The Journal of antimicrobial chemotherapy, 2018, 04-01, Volume: 73, Issue:suppl_5

    Topics: Adolescent; Adult; Aged; Anti-Bacterial Agents; Cefuroxime; Community-Acquired Infections; Czech Rep

2018
A prospective, observational, epidemiological evaluation of the aetiology and antimicrobial susceptibility of acute otitis media in Saudi children younger than 5years of age.
    Journal of epidemiology and global health, 2014, Volume: 4, Issue:3

    Topics: Acute Disease; Anti-Bacterial Agents; Cefotaxime; Cefuroxime; Child, Preschool; Drug Resistance, Mul

2014
Paediatric empyema in New Zealand: a tale of two cities.
    The New Zealand medical journal, 2015, May-29, Volume: 128, Issue:1415

    Topics: Adolescent; Amoxicillin-Potassium Clavulanate Combination; Anti-Bacterial Agents; Cefotaxime; Cefuro

2015
Estimation of cefuroxime dosage using pharmacodynamic targets, MIC distributions, and minimization of a risk function.
    Journal of clinical pharmacology, 2008, Volume: 48, Issue:11

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Cefuroxime; Creatinine; Drug Admi

2008
In vitro bactericidal activities of ABT-773 against ermB strains of Streptococcus pneumoniae.
    Antimicrobial agents and chemotherapy, 2003, Volume: 47, Issue:3

    Topics: Amoxicillin-Potassium Clavulanate Combination; Cefuroxime; Cephalosporins; Culture Media; Drug Thera

2003
Pulmonary abscess of viral-bacterial etiology in a neonate.
    European journal of pediatrics, 2007, Volume: 166, Issue:12

    Topics: Anti-Infective Agents; Cefuroxime; Cephalexin; Escherichia coli Infections; Female; Humans; Infant,

2007
[Experimental study of the antibiotic activity of cefuroxime].
    Antibiotiki, 1982, Volume: 27, Issue:8

    Topics: Animals; Bacteria; Cefuroxime; Cephalosporins; Drug Evaluation, Preclinical; In Vitro Techniques; Mi

1982
In vivo correlates for Streptococcus pneumoniae penicillin resistance in acute otitis media.
    Antimicrobial agents and chemotherapy, 1995, Volume: 39, Issue:1

    Topics: Acute Disease; Cefuroxime; Child, Preschool; Humans; Infant; Microbial Sensitivity Tests; Otitis Med

1995
More about cefuroxime screening test for pneumococci.
    Journal of clinical microbiology, 1995, Volume: 33, Issue:4

    Topics: Cefuroxime; Cephalosporin Resistance; Child; Data Interpretation, Statistical; Diagnostic Errors; Ev

1995
Comparison of three commercial MIC systems, E test, fastidious antimicrobial susceptibility panel, and FOX fastidious panel, for confirmation of penicillin and cephalosporin resistance in Streptococcus pneumoniae.
    Journal of clinical microbiology, 1994, Volume: 32, Issue:9

    Topics: Cefotaxime; Cefuroxime; Cephalosporin Resistance; Humans; Microbial Sensitivity Tests; Penicillin Re

1994
In vitro evaluation of cefodizime, cefuroxime, ceftriaxone against respiratory pathogens.
    Journal of chemotherapy (Florence, Italy), 1994, Volume: 6, Issue:1

    Topics: Cefotaxime; Ceftriaxone; Cefuroxime; Haemophilus Infections; Haemophilus influenzae; Humans; Klebsie

1994
Subperiosteal orbital abscess in children: diagnosis, microbiology, and management.
    The Laryngoscope, 1993, Volume: 103, Issue:1 Pt 1

    Topics: Abscess; Adolescent; Bacteria; Cefuroxime; Child; Child, Preschool; Ethmoid Sinus; Female; Haemophil

1993
In vitro activities of oral antimicrobial agents against penicillin-resistant Streptococcus pneumoniae: implications for outpatient treatment.
    Southern medical journal, 1997, Volume: 90, Issue:6

    Topics: Administration, Oral; Adult; Ambulatory Care; Anti-Bacterial Agents; Azithromycin; Cefaclor; Cefproz

1997
Choice of an oral beta-lactam antibiotic for infections due to penicillin-resistant Streptococcus pneumoniae.
    Scandinavian journal of infectious diseases, 1997, Volume: 29, Issue:3

    Topics: Administration, Oral; Amoxicillin; beta-Lactam Resistance; Cefaclor; Cefixime; Cefotaxime; Cefpodoxi

1997
In-vitro activity of 21 beta-lactam antibiotics against penicillin-susceptible and penicillin-resistant Streptococcus pneumoniae.
    The Journal of antimicrobial chemotherapy, 1998, Volume: 41, Issue:3

    Topics: Amoxicillin; Ampicillin; Anti-Bacterial Agents; beta-Lactams; Carbapenems; Cefaclor; Cefadroxil; Cef

1998
In vivo efficacies of amoxicillin and cefuroxime against penicillin-resistant Streptococcus pneumoniae in a gerbil model of acute otitis media.
    Antimicrobial agents and chemotherapy, 1998, Volume: 42, Issue:6

    Topics: Acute Disease; Amoxicillin; Animals; Cefuroxime; Disease Models, Animal; Drug Therapy, Combination;

1998
[Development of resistance to beta-lactams and other antibiotics of pneumococci isolated from acute otitis media in France: statement of the National Reference Center 1995-1996].
    Archives de pediatrie : organe officiel de la Societe francaise de pediatrie, 1998, Volume: 5, Issue:9

    Topics: Acute Disease; Amoxicillin; beta-Lactam Resistance; beta-Lactams; Cefpodoxime; Ceftizoxime; Cefuroxi

1998
In vitro activity of newer quinolones on Streptococcus pneumoniae isolated from outpatients.
    Acta clinica Belgica, 1998, Volume: 53, Issue:4

    Topics: Amoxicillin-Potassium Clavulanate Combination; Anti-Bacterial Agents; Anti-Infective Agents; Cefurox

1998
Antimicrobial resistance of 1,113 Streptococcus pneumoniae isolates from patients with respiratory tract infections in Spain: results of a 1-year (1996-1997) multicenter surveillance study. The Spanish Surveillance Group for Respiratory Pathogens.
    Antimicrobial agents and chemotherapy, 1999, Volume: 43, Issue:2

    Topics: Cefuroxime; Cephalosporins; Drug Resistance, Microbial; Humans; Microbial Sensitivity Tests; Penicil

1999
Predicting susceptibility of Streptococcus pneumoniae to ceftriaxone and cefotaxime by cefuroxime and ceftizoxime disk diffusion testing.
    Journal of clinical microbiology, 1999, Volume: 37, Issue:11

    Topics: Cefotaxime; Ceftizoxime; Ceftriaxone; Cefuroxime; Cephalosporin Resistance; Evaluation Studies as To

1999
Role of Streptococcus pneumoniae and Haemophilus influenzae in the development of acute otitis media and otitis media with effusion in a gerbil model.
    The Journal of infectious diseases, 2000, Volume: 181, Issue:2

    Topics: Acute Disease; Amoxicillin-Potassium Clavulanate Combination; Animals; Cefuroxime; Cephalosporins; C

2000
Penicillin-resistant and -intermediate Streptococcus pneumoniae in Saudi Arabia.
    Journal of chemotherapy (Florence, Italy), 2000, Volume: 12, Issue:2

    Topics: Amoxicillin; Anti-Bacterial Agents; Ceftriaxone; Cefuroxime; Cephalosporins; Clarithromycin; Humans;

2000
Pneumococcal psoas abscess: report of two cases.
    Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases, 2000, Volume: 6, Issue:3

    Topics: Cefotaxime; Cefuroxime; Cephalosporins; Female; Humans; Male; Middle Aged; Pneumococcal Infections;

2000
Prediction of in-vivo efficacy by in-vitro early bactericidal activity with oral beta-lactams, in a dose-ranging immunocompetent mouse sepsis model, using strains of Streptococcus pneumoniae with decreasing susceptibilities to penicillin.
    Journal of chemotherapy (Florence, Italy), 2001, Volume: 13, Issue:2

    Topics: Amoxicillin; Animals; Area Under Curve; Cefpodoxime; Ceftizoxime; Cefuroxime; Cephalosporins; Diseas

2001
Outcome of invasive infections outside the central nervous system caused by Streptococcus pneumoniae isolates nonsusceptible to ceftriazone in children treated with beta-lactam antibiotics.
    The Pediatric infectious disease journal, 2001, Volume: 20, Issue:4

    Topics: Anti-Bacterial Agents; Bacteremia; Cefotaxime; Ceftriaxone; Cefuroxime; Cephalosporin Resistance; Ce

2001
Pneumococcal bacteraemia in south Auckland: a five year review with emphasis on prescribing practices.
    The New Zealand medical journal, 1992, Oct-14, Volume: 105, Issue:943

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amoxicillin; Anti-Bacterial Agents; Bacteremia; Cefuroxi

1992
Nasopharyngeal carriage of antibiotic-resistant pneumococci by children in group day care.
    The Journal of infectious diseases, 1988, Volume: 157, Issue:2

    Topics: Amoxicillin; Carrier State; Cefuroxime; Child Day Care Centers; Child, Preschool; Drug Combinations;

1988
Interaction between beta-lactam antibiotics and gentamicin against Streptococcus pneumoniae in vitro and in vivo.
    Acta pathologica, microbiologica, et immunologica Scandinavica. Section B, Microbiology, 1987, Volume: 95, Issue:5

    Topics: Ampicillin; Animals; Anti-Bacterial Agents; Cefuroxime; Drug Synergism; Drug Therapy, Combination; F

1987
Experimental pneumococcus infection in mice: comparative in vitro and in vivo effect of cefuroxime, cefotaxime and ceftriaxone.
    Acta pathologica, microbiologica, et immunologica Scandinavica. Section B, Microbiology, 1987, Volume: 95, Issue:5

    Topics: Animals; Cefotaxime; Ceftriaxone; Cefuroxime; Cephalosporins; Female; Mice; Microbial Sensitivity Te

1987
Cefuroxime therapy for bacteremic soft-tissue infections in children.
    American journal of diseases of children (1960), 1985, Volume: 139, Issue:11

    Topics: beta-Lactamases; Cefuroxime; Cellulitis; Cephalosporins; Child, Preschool; Drug Resistance, Microbia

1985