cefuroxime has been researched along with Pachymeningitis in 34 studies
Cefuroxime: Broad-spectrum cephalosporin antibiotic resistant to beta-lactamase. It has been proposed for infections with gram-negative and gram-positive organisms, GONORRHEA, and HAEMOPHILUS.
cefuroxime : A 3-(carbamoyloxymethyl)cephalosporin compound having a 7-(2Z)-2-(furan-2-yl)-2-(methoxyimino)acetamido side chain.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To compare ceftriaxone with cefuroxime for the treatment of meningitis, we conducted a study in which 106 children with acute bacterial meningitis were randomly assigned to receive either ceftriaxone (100 mg per kilogram of body weight per day, administered intravenously once daily; n = 53) or cefuroxime (240 mg per kilogram per day, administered intravenously in four equal doses; n = 53)." | 9.06 | A comparison of ceftriaxone and cefuroxime for the treatment of bacterial meningitis in children. ( Auckenthaler, R; Bernath, O; Cheseaux, JJ; Gianella-Borradori, A; Pfenninger, J; Schaad, UB; Suter, S; Wedgwood, J, 1990) |
| "To assess the comparative efficacy of cefuroxime and ceftriaxone for the treatment of bacterial meningitis, we reviewed the records from four prospective efficacy trials conducted at our institution." | 9.06 | Comparative efficacy of ceftriaxone and cefuroxime for treatment of bacterial meningitis. ( Hoyt, MJ; Lebel, MH; McCracken, GH, 1989) |
| "In a multicenter randomized trial, 107 children with bacterial meningitis were initially given either cefuroxime or ampicillin plus chloramphenicol." | 9.06 | Cefuroxime versus ampicillin plus chloramphenicol in childhood bacterial meningitis: a multicenter randomized controlled trial. ( Abramson, JS; Ayoub, EM; Chartrand, SA; Cox, FE; Geffen, WA; Harrison, CJ; Harrison, D; Marks, MI; Marks, WA; Stutman, HR, 1986) |
| "Forty-eight infants and children with bacterial meningitis received daily dosages of cefuroxime ranging from 90 to 300 mg/kg during the first two to four days of treatment and 45 to 149 mg/kg during the subsequent six to eight days of treatment." | 7.66 | The efficacy of cefuroxime in the treatment of bacterial meningitis in infants and children. ( Bahaeldin, HK; Elbaroudy, R; Omran, N, 1983) |
| "The following results were obtained from the fundamental and clinical studies of cefuroxime, a new synthetic cephalosporin, in pediatric patients with purulent meningitis." | 7.66 | [Fundamental and clinical studies of cefuroxime in pediatric purulent meningitis (author's transl)]. ( Hori, M; Kumagai, K; Kurosu, Y; Toyonaga, Y, 1980) |
| "In order to find an alternative antimicrobial treatment for childhood bacterial meningitis 30 infants and children with meningitis, due to Haemophilus influenzae (n = 13), Neisseria meningitis (n = 9), Streptococcus pneumoniae (n = 5), or meningitis of unknown aetiology (n = 3), were treated with cefuroxime, 200 mg/kg a day, as the only antibiotic." | 7.66 | Cefuroxime in bacterial meningitis. ( Lütschg, J; Nussbaumer, A; Pfenninger, J; Schaad, UB; Zellweger, U, 1982) |
| "A total of 38 patients with bacterial meningitis received either 50 or 75 mg of cefuroxime per kg of body weight given as a 15-min intravenous infusion during the first to third days of therapy." | 7.66 | Pharmacokinetics of cefuroxime in infants and children with bacterial meningitis. ( Chrane, DF; del Rio, Mde L; McCracken, GH; Nelson, JD; Shelton, S, 1982) |
| "Cefuroxime was given to 5 neurosurgical patients intravenously in intervals of 8 h." | 5.26 | Investigations of cefuroxime levels in cerebrospinal fluid of patients with and without meningitis. ( Daschner, FD; Friedrich, H; Haensel-Friedrich, G; Langmaak, H, 1980) |
| "To compare ceftriaxone with cefuroxime for the treatment of meningitis, we conducted a study in which 106 children with acute bacterial meningitis were randomly assigned to receive either ceftriaxone (100 mg per kilogram of body weight per day, administered intravenously once daily; n = 53) or cefuroxime (240 mg per kilogram per day, administered intravenously in four equal doses; n = 53)." | 5.06 | A comparison of ceftriaxone and cefuroxime for the treatment of bacterial meningitis in children. ( Auckenthaler, R; Bernath, O; Cheseaux, JJ; Gianella-Borradori, A; Pfenninger, J; Schaad, UB; Suter, S; Wedgwood, J, 1990) |
| "To assess the comparative efficacy of cefuroxime and ceftriaxone for the treatment of bacterial meningitis, we reviewed the records from four prospective efficacy trials conducted at our institution." | 5.06 | Comparative efficacy of ceftriaxone and cefuroxime for treatment of bacterial meningitis. ( Hoyt, MJ; Lebel, MH; McCracken, GH, 1989) |
| "To determine the clinical importance of CSF cultures that are persistently positive for pathogens in patients treated for meningitis with the new cephalosporins, the records of 301 infants and children with bacterial meningitis enrolled prospectively in four clinical efficacy trials of cefuroxime or ceftriaxone therapy were reviewed." | 5.06 | Delayed cerebrospinal fluid sterilization and adverse outcome of bacterial meningitis in infants and children. ( Lebel, MH; McCracken, GH, 1989) |
| "In a multicenter randomized trial, 107 children with bacterial meningitis were initially given either cefuroxime or ampicillin plus chloramphenicol." | 5.06 | Cefuroxime versus ampicillin plus chloramphenicol in childhood bacterial meningitis: a multicenter randomized controlled trial. ( Abramson, JS; Ayoub, EM; Chartrand, SA; Cox, FE; Geffen, WA; Harrison, CJ; Harrison, D; Marks, MI; Marks, WA; Stutman, HR, 1986) |
| "Ampicillin (or penicillin G) plus chloramphenicol, cefuroxime, ceftriaxone, and cefotaxime have been used in the treatment of bacterial meningitis beyond the neonatal period." | 3.68 | Delayed cerebrospinal fluid sterilization, in vitro bactericidal activities, and side effects of selected beta-lactams. ( Dajani, AS; Pokowski, LH, 1990) |
| "Ampicillin and chloramphenicol have been used for initial empiric therapy of childhood meningitis since the mid-1970s." | 3.67 | Cephalosporin therapy for childhood meningitis. ( Ryan, ME; Smith, MA, 1987) |
| "Forty-eight infants and children with bacterial meningitis received daily dosages of cefuroxime ranging from 90 to 300 mg/kg during the first two to four days of treatment and 45 to 149 mg/kg during the subsequent six to eight days of treatment." | 3.66 | The efficacy of cefuroxime in the treatment of bacterial meningitis in infants and children. ( Bahaeldin, HK; Elbaroudy, R; Omran, N, 1983) |
| "The following results were obtained from the fundamental and clinical studies of cefuroxime, a new synthetic cephalosporin, in pediatric patients with purulent meningitis." | 3.66 | [Fundamental and clinical studies of cefuroxime in pediatric purulent meningitis (author's transl)]. ( Hori, M; Kumagai, K; Kurosu, Y; Toyonaga, Y, 1980) |
| "In order to find an alternative antimicrobial treatment for childhood bacterial meningitis 30 infants and children with meningitis, due to Haemophilus influenzae (n = 13), Neisseria meningitis (n = 9), Streptococcus pneumoniae (n = 5), or meningitis of unknown aetiology (n = 3), were treated with cefuroxime, 200 mg/kg a day, as the only antibiotic." | 3.66 | Cefuroxime in bacterial meningitis. ( Lütschg, J; Nussbaumer, A; Pfenninger, J; Schaad, UB; Zellweger, U, 1982) |
| "A total of 38 patients with bacterial meningitis received either 50 or 75 mg of cefuroxime per kg of body weight given as a 15-min intravenous infusion during the first to third days of therapy." | 3.66 | Pharmacokinetics of cefuroxime in infants and children with bacterial meningitis. ( Chrane, DF; del Rio, Mde L; McCracken, GH; Nelson, JD; Shelton, S, 1982) |
| "Cefuroxime has a second-generation cephalosporin spectrum of activity similar to cefamandole." | 2.36 | Cefuroxime: antimicrobial activity, Pharmacology, and clinical efficacy. ( LeFrock, JL; Smith, BR, 1983) |
| "Cefuroxime was given to 5 neurosurgical patients intravenously in intervals of 8 h." | 1.26 | Investigations of cefuroxime levels in cerebrospinal fluid of patients with and without meningitis. ( Daschner, FD; Friedrich, H; Haensel-Friedrich, G; Langmaak, H, 1980) |
| "1." | 1.26 | [Study of cefuroxime in pediatric field (author's transl)]. ( Inaguma, K; Iwai, N; Miyazu, M; Osuga, T; Sasaki, A, 1979) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 26 (76.47) | 18.7374 |
| 1990's | 8 (23.53) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Smith, BR | 1 |
| LeFrock, JL | 1 |
| Sirinavin, S | 1 |
| Chiemchanya, S | 1 |
| Visudhipan, P | 1 |
| Lolekha, S | 1 |
| Bahaeldin, HK | 1 |
| Elbaroudy, R | 1 |
| Omran, N | 1 |
| Toyonaga, Y | 1 |
| Kurosu, Y | 1 |
| Kumagai, K | 1 |
| Hori, M | 1 |
| Tärnvik, A | 1 |
| Burman, LA | 1 |
| Falsen, E | 1 |
| Pfenninger, J | 2 |
| Schaad, UB | 2 |
| Lütschg, J | 1 |
| Nussbaumer, A | 1 |
| Zellweger, U | 1 |
| del Rio, Mde L | 1 |
| Chrane, DF | 1 |
| Shelton, S | 1 |
| McCracken, GH | 4 |
| Nelson, JD | 1 |
| Netland, A | 2 |
| Müller, C | 2 |
| Andrew, E | 2 |
| Friedrich, H | 1 |
| Haensel-Friedrich, G | 1 |
| Langmaak, H | 1 |
| Daschner, FD | 1 |
| Dawson, AF | 1 |
| Marget, W | 1 |
| Belohradsky, BH | 1 |
| Roos, R | 1 |
| Kobayashi, Y | 1 |
| Morikawa, Y | 1 |
| Haruta, T | 1 |
| Fujiwara, T | 1 |
| Iwai, N | 1 |
| Sasaki, A | 1 |
| Miyazu, M | 1 |
| Osuga, T | 1 |
| Inaguma, K | 1 |
| Corbeel, L | 1 |
| Van Acker, G | 1 |
| Eeckels, R | 1 |
| Vandepitte, J | 1 |
| Verbist, L | 1 |
| Finch, RG | 1 |
| Mandragos, C | 1 |
| Dajani, AS | 1 |
| Pokowski, LH | 1 |
| Gothefors, L | 1 |
| Bass, JW | 1 |
| Person, DA | 1 |
| Fonseca, RJ | 1 |
| Weiss, D | 1 |
| Glaser, JH | 1 |
| Wrenn, K | 1 |
| Suter, S | 1 |
| Gianella-Borradori, A | 1 |
| Auckenthaler, R | 1 |
| Bernath, O | 1 |
| Cheseaux, JJ | 1 |
| Wedgwood, J | 1 |
| Smith, ML | 1 |
| Abramson, JS | 2 |
| Hampton, KD | 1 |
| Wasilauskas, BL | 1 |
| Lebel, MH | 2 |
| Hoyt, MJ | 1 |
| Steele, RW | 1 |
| Poulsgård, L | 1 |
| Buhl, MR | 1 |
| Eichenwald, HF | 1 |
| Stutman, HR | 2 |
| Marks, MI | 2 |
| Smith, MA | 1 |
| Ryan, ME | 1 |
| Marks, WA | 1 |
| Ayoub, EM | 1 |
| Chartrand, SA | 1 |
| Cox, FE | 1 |
| Geffen, WA | 1 |
| Harrison, CJ | 1 |
| Harrison, D | 1 |
| Klein, JO | 1 |
| Feigin, RD | 1 |
2 reviews available for cefuroxime and Pachymeningitis
| Article | Year |
|---|---|
Cefuroxime: antimicrobial activity, Pharmacology, and clinical efficacy.
Topics: Cefuroxime; Cephalosporins; Enterobacteriaceae; Gonorrhea; Humans; Kinetics; Lung Diseases; Meningit | 1983 |
Bacterial meningitis in children: diagnosis and therapy. A review of recent developments.
Topics: Age Factors; Aminoglycosides; Ampicillin; Anti-Bacterial Agents; Bacteria; Cefotaxime; Ceftriaxone; | 1987 |
5 trials available for cefuroxime and Pachymeningitis
| Article | Year |
|---|---|
Cefuroxime versus ampicillin and chloramphenicol for the treatment of bacterial meningitis. Report from a Swedish Study Group.
Topics: Ampicillin; Bacterial Infections; Cefuroxime; Cephalosporins; Chloramphenicol; Clinical Trials as To | 1982 |
A comparison of ceftriaxone and cefuroxime for the treatment of bacterial meningitis in children.
Topics: Adolescent; Bacterial Infections; Ceftriaxone; Cefuroxime; Cephalosporins; Cerebrospinal Fluid; Chil | 1990 |
Comparative efficacy of ceftriaxone and cefuroxime for treatment of bacterial meningitis.
Topics: Adolescent; Ceftriaxone; Cefuroxime; Cephalosporins; Child; Child, Preschool; Clinical Trials as Top | 1989 |
Delayed cerebrospinal fluid sterilization and adverse outcome of bacterial meningitis in infants and children.
Topics: Bacteria; Bacterial Infections; Ceftriaxone; Cefuroxime; Cephalosporins; Cerebrospinal Fluid; Child, | 1989 |
Cefuroxime versus ampicillin plus chloramphenicol in childhood bacterial meningitis: a multicenter randomized controlled trial.
Topics: Adolescent; Ampicillin; Bacterial Infections; Cefuroxime; Cephalosporins; Child; Child, Preschool; C | 1986 |
27 other studies available for cefuroxime and Pachymeningitis
| Article | Year |
|---|---|
Cefuroxime treatment of bacterial meningitis in infants and children.
Topics: Body Fluids; Cefuroxime; Cephalosporins; Child; Child, Preschool; Drug Resistance, Microbial; Haemop | 1984 |
The efficacy of cefuroxime in the treatment of bacterial meningitis in infants and children.
Topics: Adolescent; Bacteria; Cefuroxime; Cephalosporins; Child; Child, Preschool; Female; Humans; Infant; I | 1983 |
[Fundamental and clinical studies of cefuroxime in pediatric purulent meningitis (author's transl)].
Topics: Cefuroxime; Cephalosporins; Child, Preschool; Drug Evaluation; Escherichia coli Infections; Female; | 1980 |
Dwarf colony mutant of Escherichia coli causing purulent meningitis.
Topics: Aged; Ampicillin; Cefuroxime; Escherichia coli; Female; Humans; Meningitis; Mutation | 1982 |
Cefuroxime in bacterial meningitis.
Topics: Cefuroxime; Cephalosporins; Child; Child, Preschool; Female; Humans; Infant; Male; Meningitis | 1982 |
Pharmacokinetics of cefuroxime in infants and children with bacterial meningitis.
Topics: Cefuroxime; Cephalosporins; Child; Child, Preschool; Female; Half-Life; Humans; Infant; Kinetics; Ma | 1982 |
Concentration of cefuroxime in cerebrospinal fluid in patients with bacterial meningitis.
Topics: Adolescent; Adult; Aged; Cefuroxime; Cephalosporins; Female; Humans; Male; Meningitis; Middle Aged | 1981 |
Investigations of cefuroxime levels in cerebrospinal fluid of patients with and without meningitis.
Topics: Adult; Cefuroxime; Cephalosporins; Female; Humans; Male; Meningitis; Middle Aged; Time Factors | 1980 |
The penetration of cefuroxime into the cerebrospinal fluid through inflamed and non-inflamed meninges.
Topics: Adolescent; Adult; Aged; Cefuroxime; Cephalosporins; Female; Humans; Male; Meninges; Meningitis; Mid | 1980 |
Guidelines for adequate chemotherapeutic dosage in newborns and infants with septicaemia and meningitis.
Topics: Amikacin; Anti-Bacterial Agents; Cefuroxime; Colistin; Dose-Response Relationship, Drug; Humans; Inf | 1980 |
[Fundamental and clinical studies on cefuroxime in children (author's transl)].
Topics: Animals; Cefazolin; Cefuroxime; Cephalosporins; Child, Preschool; Empyema; Escherichia coli; Female; | 1979 |
[Study of cefuroxime in pediatric field (author's transl)].
Topics: Bacteria; Bacterial Infections; Bronchitis; Cefuroxime; Cephalosporins; Child; Child, Preschool; Dru | 1979 |
Cefuroxime plasma and CSF levels in children with meningitis.
Topics: Cefuroxime; Cephalosporins; Child; Child, Preschool; Drug Administration Schedule; Humans; Infant; M | 1979 |
Corticosteroids in bacterial meningitis.
Topics: Adrenal Cortex Hormones; Ampicillin; Bacterial Infections; Ceftriaxone; Cefuroxime; Child; Chloramph | 1991 |
Delayed cerebrospinal fluid sterilization, in vitro bactericidal activities, and side effects of selected beta-lactams.
Topics: Ampicillin; Anti-Bacterial Agents; Bacteria; Cefotaxime; Ceftriaxone; Cefuroxime; Cerebrospinal Flui | 1990 |
[Cefuroxime has a good effect in severe infections in children].
Topics: Aminoglycosides; Anti-Bacterial Agents; Cefuroxime; Child, Preschool; Humans; Infant; Infant, Newbor | 1990 |
Initial therapy for bacterial meningitis. Infectious Diseases and Immunization Committee, Canadian Paediatric Society.
Topics: Bacterial Infections; Ceftriaxone; Cefuroxime; Cephalosporins; Cerebrospinal Fluid; Child; Humans; I | 1990 |
Cefuroxime versus ceftriaxone for bacterial meningitis.
Topics: Ceftriaxone; Cefuroxime; Cephalosporins; Child; Hearing Loss; Humans; Incidence; Infant; Meningitis | 1990 |
Ceftriaxone versus cefuroxime for treatment of bacterial meningitis.
Topics: Bacterial Infections; Ceftriaxone; Cefuroxime; Cephalosporins; Humans; Meningitis | 1990 |
Ceftriaxone versus cefuroxime for meningitis in children.
Topics: Bacterial Infections; Ceftriaxone; Cefuroxime; Cephalosporins; Child; Humans; Meningitis | 1990 |
Salmonella meningitis. Unusual presentation and successful treatment with cefuroxime.
Topics: Cefuroxime; Cephalosporins; Cerebrospinal Fluid; Humans; Infant; Lymphocytes; Male; Meningitis; Salm | 1989 |
Cephalosporins for bacterial meningitis: which one is best?
Topics: Ceftriaxone; Cefuroxime; Cephalosporins; Child; Drug Evaluation; Humans; Infant; Meningitis | 1989 |
[Results of treatment of meningitis during a 10-year period].
Topics: Adult; Cefuroxime; Denmark; Humans; Meningitis; Middle Aged; Prognosis; Streptococcus pneumoniae | 1989 |
Bacterial meningitis: is there a "best" antimicrobial therapy?
Topics: Cefoperazone; Ceftazidime; Ceftriaxone; Cefuroxime; Cephalosporins; Child; Humans; Infant, Newborn; | 1987 |
Cephalosporin therapy for childhood meningitis.
Topics: Adolescent; Ampicillin; Bone Marrow Diseases; Ceftriaxone; Cefuroxime; Cephalosporins; Child; Child, | 1987 |
Questions about task force on meningitis--recommendations.
Topics: Cefuroxime; Humans; Infant; Meningitis; Meningitis, Haemophilus; Spinal Puncture | 1987 |
Initial antibiotic treatment of bacterial meningitis in children. Infectious Diseases and Immunization Committee, Canadian Paediatric Society.
Topics: Anti-Bacterial Agents; Bacterial Infections; Cefotaxime; Ceftriaxone; Cefuroxime; Drug Administratio | 1986 |