cefuroxime has been researched along with Otitis Media with Effusion in 14 studies
Cefuroxime: Broad-spectrum cephalosporin antibiotic resistant to beta-lactamase. It has been proposed for infections with gram-negative and gram-positive organisms, GONORRHEA, and HAEMOPHILUS.
cefuroxime : A 3-(carbamoyloxymethyl)cephalosporin compound having a 7-(2Z)-2-(furan-2-yl)-2-(methoxyimino)acetamido side chain.
Otitis Media with Effusion: Inflammation of the middle ear with a clear pale yellow-colored transudate.
Excerpt | Relevance | Reference |
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"In this open, single center study, the concentration of cefuroxime achieved in the serum and middle ear effusion of pediatric acute otitis media patients with purulent effusion was assessed between 2 and 5 h after a single oral dose of 15 mg/kg cefuroxime axetil suspension." | 9.08 | Concentration of cefuroxime in middle ear effusion of children with acute otitis media. ( Efthymiopoulos, C; Marr, C; Thorarinsson, H; Thoroddsen, E, 1997) |
"This trial compared the efficacy and safety of a 10-day treatment course of cefaclor and cefuroxime axetil in the treatment of acute otitis media with effusion in children who failed therapy with amoxicillin." | 9.08 | Comparison of cefaclor and cefuroxime axetil in the treatment of acute otitis media with effusion in children who failed amoxicillin therapy. ( Johns, D; Turik, MA, 1998) |
"Two hundred sixty-three pediatric patients from the ages of 3 months to 11 years were enrolled in a randomized, investigator-blinded, multicenter study comparing the clinical and bacteriological efficacies and safety of cefuroxime axetil suspension (CAE) with those of amoxicillin-clavulanate suspension (AMX-CL) in the treatment of acute otitis media with effusion." | 9.07 | Comparison of cefuroxime axetil and amoxicillin-clavulanate suspensions in treatment of acute otitis media with effusion in children. ( Aronovitz, G; Bodor, F; Goldfarb, J; McLinn, SE; Moskal, M; Ossi, MJ; Schwartz, R; Self, P, 1994) |
"Cefuroxime axetil was evaluated for clinical efficacy and tolerance in the treatment of acute otitis media in children." | 9.07 | Cefuroxime axetil in the treatment of acute otitis media in children. ( Beratis, NG; Goumas, PD; Haliotis, FA; Lygatsikas, CG; Spyropoulos, CD; Syrogiannopoulos, GA, 1992) |
" The study was undertaken to determine the concentrations of cefuroxime in the blood and middle ear effusions (MEE) of children between 6 and 12 years of age with acute otitis media and chronic OME after a single oral dose administration of cefuroxime axetil, the ester prodrug of cefuroxime." | 7.68 | Concentration of cefuroxime in serum and middle ear effusion after single dose treatment with cefuroxime axetil. ( Bluestone, CD; Collins, JJ; Haddad, J; Hart, RW; Isaacson, G; Respler, DS; Yilmaz, HM, 1991) |
"In this open, single center study, the concentration of cefuroxime achieved in the serum and middle ear effusion of pediatric acute otitis media patients with purulent effusion was assessed between 2 and 5 h after a single oral dose of 15 mg/kg cefuroxime axetil suspension." | 5.08 | Concentration of cefuroxime in middle ear effusion of children with acute otitis media. ( Efthymiopoulos, C; Marr, C; Thorarinsson, H; Thoroddsen, E, 1997) |
"This trial compared the efficacy and safety of a 10-day treatment course of cefaclor and cefuroxime axetil in the treatment of acute otitis media with effusion in children who failed therapy with amoxicillin." | 5.08 | Comparison of cefaclor and cefuroxime axetil in the treatment of acute otitis media with effusion in children who failed amoxicillin therapy. ( Johns, D; Turik, MA, 1998) |
"Two hundred sixty-three pediatric patients from the ages of 3 months to 11 years were enrolled in a randomized, investigator-blinded, multicenter study comparing the clinical and bacteriological efficacies and safety of cefuroxime axetil suspension (CAE) with those of amoxicillin-clavulanate suspension (AMX-CL) in the treatment of acute otitis media with effusion." | 5.07 | Comparison of cefuroxime axetil and amoxicillin-clavulanate suspensions in treatment of acute otitis media with effusion in children. ( Aronovitz, G; Bodor, F; Goldfarb, J; McLinn, SE; Moskal, M; Ossi, MJ; Schwartz, R; Self, P, 1994) |
"Cefuroxime axetil was evaluated for clinical efficacy and tolerance in the treatment of acute otitis media in children." | 5.07 | Cefuroxime axetil in the treatment of acute otitis media in children. ( Beratis, NG; Goumas, PD; Haliotis, FA; Lygatsikas, CG; Spyropoulos, CD; Syrogiannopoulos, GA, 1992) |
"Cefuroxime axetil and cefaclor were compared for efficacy in the treatment of acute otitis media with effusion." | 5.06 | Treatment of otitis media with cefuroxime axetil. ( Aronovitz, GH, 1988) |
"The efficacy of amoxicillin/clavulanate and cefuroxime was determined in a gerbil model of otitis media with a mixed Streptococcus pneumoniae plus Haemophilus influenzae middle ear (ME) infection." | 3.70 | Role of Streptococcus pneumoniae and Haemophilus influenzae in the development of acute otitis media and otitis media with effusion in a gerbil model. ( Aguilar, L; Cenjor, C; García-Calvo, G; Giménez, MJ; Nieto, E; Parra, A; Ponte, C; Soriano, F, 2000) |
" The study was undertaken to determine the concentrations of cefuroxime in the blood and middle ear effusions (MEE) of children between 6 and 12 years of age with acute otitis media and chronic OME after a single oral dose administration of cefuroxime axetil, the ester prodrug of cefuroxime." | 3.68 | Concentration of cefuroxime in serum and middle ear effusion after single dose treatment with cefuroxime axetil. ( Bluestone, CD; Collins, JJ; Haddad, J; Hart, RW; Isaacson, G; Respler, DS; Yilmaz, HM, 1991) |
"Disappearance of middle ear effusion is one of the most important outcomes in the treatment of acute otitis media (AOM)." | 2.72 | Disappearance of middle ear effusion in acute otitis media monitored daily with tympanometry. ( Jounio-Ervasti, K; Kontiokari, T; Rantala, H; Renko, M; Uhari, M, 2006) |
" The serum concentrations of cefuroxime were found to be above the minimal inhibitory concentration (MIC) for penicillin-sensitive Streptococcus pneumoniae for 100% of the dosing interval and 42% of the time for intermediate-resistant strains." | 2.69 | Measuring antibiotic levels in otitis media. ( Thoroddsen, E, 1998) |
" Although guidelines continue to endorse amoxicillin as the preferred treatment, amoxicillin/clavulanate in high dosage would be the preferred treatment based on the otopathogen mix currently." | 2.49 | Otitis media. ( Pichichero, ME, 2013) |
Timeframe | Studies, this research(%) | All Research% |
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pre-1990 | 1 (7.14) | 18.7374 |
1990's | 8 (57.14) | 18.2507 |
2000's | 4 (28.57) | 29.6817 |
2010's | 1 (7.14) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
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Pichichero, ME | 1 |
Renko, M | 1 |
Kontiokari, T | 1 |
Jounio-Ervasti, K | 1 |
Rantala, H | 1 |
Uhari, M | 1 |
Jacobs, MR | 1 |
Good, CE | 1 |
Sellner, T | 1 |
Bajaksouzian, S | 1 |
Windau, A | 1 |
Anon, JB | 1 |
McLinn, SE | 1 |
Moskal, M | 1 |
Goldfarb, J | 1 |
Bodor, F | 1 |
Aronovitz, G | 1 |
Schwartz, R | 1 |
Self, P | 1 |
Ossi, MJ | 1 |
Thoroddsen, E | 3 |
Marr, C | 2 |
Efthymiopoulos, C | 1 |
Thorarinsson, H | 1 |
Turik, MA | 1 |
Johns, D | 1 |
Ponte, C | 2 |
Cenjor, C | 2 |
Parra, A | 2 |
Nieto, E | 2 |
García-Calvo, G | 2 |
Giménez, MJ | 2 |
Aguilar, L | 2 |
Soriano, F | 2 |
Pessey, JJ | 1 |
Gehanno, P | 1 |
Dagan, R | 1 |
Leibovitz, E | 1 |
Machac, J | 1 |
Pimentel, JM | 1 |
Leblanc, F | 1 |
Spandow, O | 1 |
Gothefors, L | 1 |
Fagerlund, M | 1 |
Kristensen, B | 1 |
Holm, S | 1 |
Syrogiannopoulos, GA | 1 |
Goumas, PD | 1 |
Haliotis, FA | 1 |
Lygatsikas, CG | 1 |
Spyropoulos, CD | 1 |
Beratis, NG | 1 |
Haddad, J | 1 |
Isaacson, G | 1 |
Respler, DS | 1 |
Hart, RW | 1 |
Yilmaz, HM | 1 |
Collins, JJ | 1 |
Bluestone, CD | 1 |
Aronovitz, GH | 1 |
1 review available for cefuroxime and Otitis Media with Effusion
Article | Year |
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Otitis media.
Topics: Age Factors; Amoxicillin; Amoxicillin-Potassium Clavulanate Combination; Anti-Bacterial Agents; Bact | 2013 |
8 trials available for cefuroxime and Otitis Media with Effusion
Article | Year |
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Disappearance of middle ear effusion in acute otitis media monitored daily with tympanometry.
Topics: Acoustic Impedance Tests; Amoxicillin; Anti-Bacterial Agents; Cefuroxime; Child; Child, Preschool; F | 2006 |
Comparison of cefuroxime axetil and amoxicillin-clavulanate suspensions in treatment of acute otitis media with effusion in children.
Topics: Amoxicillin; Amoxicillin-Potassium Clavulanate Combination; Cefuroxime; Child; Child, Preschool; Cla | 1994 |
Concentration of cefuroxime in middle ear effusion of children with acute otitis media.
Topics: Acute Disease; Administration, Oral; Cefuroxime; Cephalosporins; Child, Preschool; Humans; Infant; M | 1997 |
Measuring antibiotic levels in otitis media.
Topics: Acute Disease; Administration, Oral; Cefuroxime; Cephalosporins; Child, Preschool; Drug Monitoring; | 1998 |
Comparison of cefaclor and cefuroxime axetil in the treatment of acute otitis media with effusion in children who failed amoxicillin therapy.
Topics: Administration, Oral; Amoxicillin; Cefaclor; Cefuroxime; Cephalosporins; Child, Preschool; Female; H | 1998 |
Short course therapy with cefuroxime axetil for acute otitis media: results of a randomized multicenter comparison with amoxicillin/clavulanate.
Topics: Acute Disease; Amoxicillin-Potassium Clavulanate Combination; Bacterial Infections; Cefuroxime; Ceph | 1999 |
Cefuroxime axetil in the treatment of acute otitis media in children.
Topics: Acute Disease; Amoxicillin; Cefuroxime; Child; Child, Preschool; Female; Humans; Male; Otitis Media; | 1992 |
Treatment of otitis media with cefuroxime axetil.
Topics: Acute Disease; Cefaclor; Cefuroxime; Cephalosporins; Child; Child, Preschool; Clinical Trials as Top | 1988 |
5 other studies available for cefuroxime and Otitis Media with Effusion
Article | Year |
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Nasopharyngeal carriage of respiratory pathogens in children undergoing pressure equalization tube placement in the era of pneumococcal protein conjugate vaccine use.
Topics: Adolescent; Anti-Bacterial Agents; Cefuroxime; Cephalosporin Resistance; Child; Child, Preschool; Dr | 2007 |
Antimicrobial treatment of an experimental otitis media caused by a beta-lactamase positive isolate of Haemophilus influenzae.
Topics: Amoxicillin-Potassium Clavulanate Combination; Animals; beta-Lactamases; Cefuroxime; Cephalosporins; | 1999 |
Lateral sinus thrombosis after untreated otitis media. A clinical problem--again?
Topics: Adolescent; Anticoagulants; Cefadroxil; Cefuroxime; Humans; Lateral Sinus Thrombosis; Magnetic Reson | 2000 |
Role of Streptococcus pneumoniae and Haemophilus influenzae in the development of acute otitis media and otitis media with effusion in a gerbil model.
Topics: Acute Disease; Amoxicillin-Potassium Clavulanate Combination; Animals; Cefuroxime; Cephalosporins; C | 2000 |
Concentration of cefuroxime in serum and middle ear effusion after single dose treatment with cefuroxime axetil.
Topics: Acute Disease; Administration, Oral; Cefuroxime; Child; Chronic Disease; Exudates and Transudates; F | 1991 |