cefuroxime has been researched along with Meningitis, Meningococcal in 9 studies
Cefuroxime: Broad-spectrum cephalosporin antibiotic resistant to beta-lactamase. It has been proposed for infections with gram-negative and gram-positive organisms, GONORRHEA, and HAEMOPHILUS.
cefuroxime : A 3-(carbamoyloxymethyl)cephalosporin compound having a 7-(2Z)-2-(furan-2-yl)-2-(methoxyimino)acetamido side chain.
Meningitis, Meningococcal: A fulminant infection of the meninges and subarachnoid fluid by the bacterium NEISSERIA MENINGITIDIS, producing diffuse inflammation and peri-meningeal venous thromboses. Clinical manifestations include FEVER, nuchal rigidity, SEIZURES, severe HEADACHE, petechial rash, stupor, focal neurologic deficits, HYDROCEPHALUS, and COMA. The organism is usually transmitted via nasopharyngeal secretions and is a leading cause of meningitis in children and young adults. Organisms from Neisseria meningitidis serogroups A, B, C, Y, and W-135 have been reported to cause meningitis. (From Adams et al., Principles of Neurology, 6th ed, pp689-701; Curr Opin Pediatr 1998 Feb;10(1):13-8)
| Excerpt | Relevance | Reference |
|---|---|---|
| "To compare ceftriaxone with cefuroxime for the treatment of meningitis, we conducted a study in which 106 children with acute bacterial meningitis were randomly assigned to receive either ceftriaxone (100 mg per kilogram of body weight per day, administered intravenously once daily; n = 53) or cefuroxime (240 mg per kilogram per day, administered intravenously in four equal doses; n = 53)." | 9.06 | A comparison of ceftriaxone and cefuroxime for the treatment of bacterial meningitis in children. ( Auckenthaler, R; Bernath, O; Cheseaux, JJ; Gianella-Borradori, A; Pfenninger, J; Schaad, UB; Suter, S; Wedgwood, J, 1990) |
| "To assess the comparative efficacy of cefuroxime and ceftriaxone for the treatment of bacterial meningitis, we reviewed the records from four prospective efficacy trials conducted at our institution." | 9.06 | Comparative efficacy of ceftriaxone and cefuroxime for treatment of bacterial meningitis. ( Hoyt, MJ; Lebel, MH; McCracken, GH, 1989) |
| "In a multicenter randomized trial, 107 children with bacterial meningitis were initially given either cefuroxime or ampicillin plus chloramphenicol." | 9.06 | Cefuroxime versus ampicillin plus chloramphenicol in childhood bacterial meningitis: a multicenter randomized controlled trial. ( Abramson, JS; Ayoub, EM; Chartrand, SA; Cox, FE; Geffen, WA; Harrison, CJ; Harrison, D; Marks, MI; Marks, WA; Stutman, HR, 1986) |
| "A total of 38 patients with bacterial meningitis received either 50 or 75 mg of cefuroxime per kg of body weight given as a 15-min intravenous infusion during the first to third days of therapy." | 7.66 | Pharmacokinetics of cefuroxime in infants and children with bacterial meningitis. ( Chrane, DF; del Rio, Mde L; McCracken, GH; Nelson, JD; Shelton, S, 1982) |
| "To compare ceftriaxone with cefuroxime for the treatment of meningitis, we conducted a study in which 106 children with acute bacterial meningitis were randomly assigned to receive either ceftriaxone (100 mg per kilogram of body weight per day, administered intravenously once daily; n = 53) or cefuroxime (240 mg per kilogram per day, administered intravenously in four equal doses; n = 53)." | 5.06 | A comparison of ceftriaxone and cefuroxime for the treatment of bacterial meningitis in children. ( Auckenthaler, R; Bernath, O; Cheseaux, JJ; Gianella-Borradori, A; Pfenninger, J; Schaad, UB; Suter, S; Wedgwood, J, 1990) |
| "To assess the comparative efficacy of cefuroxime and ceftriaxone for the treatment of bacterial meningitis, we reviewed the records from four prospective efficacy trials conducted at our institution." | 5.06 | Comparative efficacy of ceftriaxone and cefuroxime for treatment of bacterial meningitis. ( Hoyt, MJ; Lebel, MH; McCracken, GH, 1989) |
| "In a multicenter randomized trial, 107 children with bacterial meningitis were initially given either cefuroxime or ampicillin plus chloramphenicol." | 5.06 | Cefuroxime versus ampicillin plus chloramphenicol in childhood bacterial meningitis: a multicenter randomized controlled trial. ( Abramson, JS; Ayoub, EM; Chartrand, SA; Cox, FE; Geffen, WA; Harrison, CJ; Harrison, D; Marks, MI; Marks, WA; Stutman, HR, 1986) |
| "A total of 38 patients with bacterial meningitis received either 50 or 75 mg of cefuroxime per kg of body weight given as a 15-min intravenous infusion during the first to third days of therapy." | 3.66 | Pharmacokinetics of cefuroxime in infants and children with bacterial meningitis. ( Chrane, DF; del Rio, Mde L; McCracken, GH; Nelson, JD; Shelton, S, 1982) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (88.89) | 18.7374 |
| 1990's | 1 (11.11) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Azzoni, P | 1 |
| del Rio, Mde L | 1 |
| Chrane, DF | 1 |
| Shelton, S | 1 |
| McCracken, GH | 3 |
| Nelson, JD | 1 |
| Schaad, UB | 1 |
| Suter, S | 1 |
| Gianella-Borradori, A | 1 |
| Pfenninger, J | 1 |
| Auckenthaler, R | 1 |
| Bernath, O | 1 |
| Cheseaux, JJ | 1 |
| Wedgwood, J | 1 |
| Lebel, MH | 2 |
| Hoyt, MJ | 2 |
| Waagner, DC | 1 |
| Rollins, NK | 1 |
| Finitzo, T | 1 |
| Stutman, HR | 2 |
| Marks, MI | 2 |
| Marks, WA | 1 |
| Abramson, JS | 1 |
| Ayoub, EM | 1 |
| Chartrand, SA | 1 |
| Cox, FE | 1 |
| Geffen, WA | 1 |
| Harrison, CJ | 1 |
| Harrison, D | 1 |
1 review available for cefuroxime and Meningitis, Meningococcal
| Article | Year |
|---|---|
Bacterial meningitis in children: diagnosis and therapy. A review of recent developments.
Topics: Age Factors; Aminoglycosides; Ampicillin; Anti-Bacterial Agents; Bacteria; Cefotaxime; Ceftriaxone; | 1987 |
5 trials available for cefuroxime and Meningitis, Meningococcal
| Article | Year |
|---|---|
Cefuroxime versus ampicillin and chloramphenicol for the treatment of bacterial meningitis. Report from a Swedish Study Group.
Topics: Ampicillin; Bacterial Infections; Cefuroxime; Cephalosporins; Chloramphenicol; Clinical Trials as To | 1982 |
A comparison of ceftriaxone and cefuroxime for the treatment of bacterial meningitis in children.
Topics: Adolescent; Bacterial Infections; Ceftriaxone; Cefuroxime; Cephalosporins; Cerebrospinal Fluid; Chil | 1990 |
Magnetic resonance imaging and dexamethasone therapy for bacterial meningitis.
Topics: Adolescent; Body Water; Brain; Cefuroxime; Child; Child, Preschool; Clinical Trials as Topic; Dexame | 1989 |
Comparative efficacy of ceftriaxone and cefuroxime for treatment of bacterial meningitis.
Topics: Adolescent; Ceftriaxone; Cefuroxime; Cephalosporins; Child; Child, Preschool; Clinical Trials as Top | 1989 |
Cefuroxime versus ampicillin plus chloramphenicol in childhood bacterial meningitis: a multicenter randomized controlled trial.
Topics: Adolescent; Ampicillin; Bacterial Infections; Cefuroxime; Cephalosporins; Child; Child, Preschool; C | 1986 |
3 other studies available for cefuroxime and Meningitis, Meningococcal
| Article | Year |
|---|---|
[Cefuroxime-tobramycin treatment of bacterial infections in cancer patients].
Topics: Anti-Bacterial Agents; Bacterial Infections; Cefuroxime; Cephalosporins; Drug Therapy, Combination; | 1980 |
Pharmacokinetics of cefuroxime in infants and children with bacterial meningitis.
Topics: Cefuroxime; Cephalosporins; Child; Child, Preschool; Female; Half-Life; Humans; Infant; Kinetics; Ma | 1982 |
Initial antibiotic treatment of bacterial meningitis in children. Infectious Diseases and Immunization Committee, Canadian Paediatric Society.
Topics: Anti-Bacterial Agents; Bacterial Infections; Cefotaxime; Ceftriaxone; Cefuroxime; Drug Administratio | 1986 |