Page last updated: 2024-10-24

cefuroxime and MODS

cefuroxime has been researched along with MODS in 4 studies

Cefuroxime: Broad-spectrum cephalosporin antibiotic resistant to beta-lactamase. It has been proposed for infections with gram-negative and gram-positive organisms, GONORRHEA, and HAEMOPHILUS.
cefuroxime : A 3-(carbamoyloxymethyl)cephalosporin compound having a 7-(2Z)-2-(furan-2-yl)-2-(methoxyimino)acetamido side chain.

Research Excerpts

ExcerptRelevanceReference
"In addition, septic shock occurred in 6 cases (2."2.73Incidence of postoperative infections in patients undergoing coronary artery bypass grafting surgery receiving antimicrobial prophylaxis with original and generic cefuroxime. ( Falagas, M; Falagas, ME; Geroulanos, S; Karatza, D; Kriaras, I; Mastoraki, E; Michalopoulos, A; Mouchtouri, E, 2008)
"Cefuroxime was chosen as the PBP-3-active antibiotic and tobramycin represented the aminoglycosides."1.56Mode of bacterial killing affects the inflammatory response and associated organ dysfunctions in a porcine E. coli intensive care sepsis model. ( Larsson, A; Lipcsey, M; Maudsdotter, L; Sjölin, J; Skorup, P, 2020)
" The pharmacokinetic profile of cefuroxime exhibited both one and two compartmental distribution."1.35Effect of severity disease on the pharmacokinetics of cefuroxime in children with multiple organ system failure. ( Asseff, IL; Guillé, GP; Olguín, HJ; Pérez, AG; Quesada, AC; Saldaña, NG; Vieyra, AC, 2008)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (50.00)29.6817
2010's1 (25.00)24.3611
2020's1 (25.00)2.80

Authors

AuthorsStudies
Skorup, P2
Maudsdotter, L2
Lipcsey, M2
Larsson, A2
Sjölin, J2
Tano, E1
Castegren, M1
Mastoraki, E1
Michalopoulos, A1
Kriaras, I1
Mouchtouri, E1
Falagas, ME1
Falagas, M1
Karatza, D1
Geroulanos, S1
Olguín, HJ1
Asseff, IL1
Vieyra, AC1
Pérez, AG1
Saldaña, NG1
Quesada, AC1
Guillé, GP1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Tolerance and Efficacy of Amiklin Administration During Nosocomial Infections Complicating COVID-19 in the ICU[NCT05511129]1,053 participants (Actual)Observational2022-05-12Active, not recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

1 trial available for cefuroxime and MODS

ArticleYear
Incidence of postoperative infections in patients undergoing coronary artery bypass grafting surgery receiving antimicrobial prophylaxis with original and generic cefuroxime.
    The Journal of infection, 2008, Volume: 56, Issue:1

    Topics: Anti-Bacterial Agents; Antibiotic Prophylaxis; Bacteremia; Cefuroxime; Coronary Artery Bypass; Drug

2008

Other Studies

3 other studies available for cefuroxime and MODS

ArticleYear
Mode of bacterial killing affects the inflammatory response and associated organ dysfunctions in a porcine E. coli intensive care sepsis model.
    Critical care (London, England), 2020, 11-14, Volume: 24, Issue:1

    Topics: Animals; Cefuroxime; Disease Models, Animal; Endotoxins; Escherichia coli; Escherichia coli Infectio

2020
Dynamics of Endotoxin, Inflammatory Variables, and Organ Dysfunction After Treatment With Antibiotics in an Escherichia coli Porcine Intensive Care Sepsis Model.
    Critical care medicine, 2018, Volume: 46, Issue:7

    Topics: Animals; Anti-Bacterial Agents; Cefuroxime; Disease Models, Animal; Drug Therapy, Combination; Endot

2018
Effect of severity disease on the pharmacokinetics of cefuroxime in children with multiple organ system failure.
    Biological & pharmaceutical bulletin, 2008, Volume: 31, Issue:2

    Topics: Adolescent; Alanine Transaminase; Algorithms; Area Under Curve; Aspartate Aminotransferases; Cefurox

2008