Page last updated: 2024-10-24

cefuroxime and Kidney Diseases

cefuroxime has been researched along with Kidney Diseases in 16 studies

Cefuroxime: Broad-spectrum cephalosporin antibiotic resistant to beta-lactamase. It has been proposed for infections with gram-negative and gram-positive organisms, GONORRHEA, and HAEMOPHILUS.
cefuroxime : A 3-(carbamoyloxymethyl)cephalosporin compound having a 7-(2Z)-2-(furan-2-yl)-2-(methoxyimino)acetamido side chain.

Kidney Diseases: Pathological processes of the KIDNEY or its component tissues.

Research Excerpts

ExcerptRelevanceReference
"Renal parenchymal malacoplakia is a rare cause of acute renal failure."2.42Renal parenchymal malacoplakia: a rare cause of ARF with a review of recent literature. ( Chan, KW; Kung, WH; Li, R; Tam, VK, 2003)
" The concentration of drug in serum and urine was measured during treatment, and pharmacokinetic parameters were evaluated on the second and last days; the parameters obtained on the 2 days did not differ significantly."1.27Pharmacokinetics and clinical effects of cefuroxime in patients with severe renal insufficiency. ( Berg, KJ; Nilsen, OG; Walstad, RA, 1983)
" During IHF the mean terminal half-life of cefuroxime was 1."1.27Pharmacokinetics of intravenous cefuroxime during intermittent and continuous arteriovenous hemofiltration. ( Cars, O; Danielson, BG; Grahnen, A; Weiss, LG; Wikström, B, 1988)
"3 Cefuroxime was cleared, unchanged, almost exclusively by the kidneys, even when kidney function was impaired."1.26Pharmacokinetic study of cefuroxime in the elderly. ( Broekhuysen, J; Deger, F; Douchamps, J; Freschi, E; Mal, N; Neve, P; Parfait, R; Siska, G; Winand, M, 1981)
"However, an eighth patient with acute renal failure caused by bacteraemic shock rapidly recovered renal function while being treated with cefuroxime and gentamicin for 15 days after large doses of frusemide intravenously."1.26The safety of cefuroxime and gentamicin in patients with reduced renal function. ( Bax, RP; Cockram, CS; Richards, P, 1980)
" This dosage of cefuroxime was protective when given for only two consecutive days starting on the first to third days of gentamicin treatment, but enhanced gentamicin nephrotoxocity when started on the sixth or subsequent days."1.26Effect of timing of cefuroxime dosage on its protection of rats against gentamicin nephrotoxicity. ( Atkinson, RM; Capel-Edwards, K; Foord, RD; Harman, IW; Patterson, GG; Pratt, DA; Wheeldon, JM, 1980)

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-199010 (62.50)18.7374
1990's1 (6.25)18.2507
2000's5 (31.25)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Taskinen, S1
Giordano, S1
Rintala, R1
Reirden, DH1
Menchise, AN1
Knox, B1
Gereige, R1
Howard, T1
Thomas, EL1
Connelly, R1
Tyler, S1
McPeak, K1
Ladhani, S1
Gransden, W1
Tam, VK1
Kung, WH1
Li, R1
Chan, KW1
Calvert, LD1
Collins, M1
Bateman, JR1
Trollfors, B2
Alestig, K1
Rödjer, S1
Sandberg, T1
Westin, J1
Suurkula, M1
Price, JD1
Norrby, R1
Walstad, RA1
Nilsen, OG1
Berg, KJ1
Weinstein, AJ1
Bundtzen, RW1
Toothaker, RD1
Nielson, OS1
Madsen, PO1
Welling, PG1
Craig, WA1
Broekhuysen, J1
Deger, F1
Douchamps, J1
Freschi, E1
Mal, N1
Neve, P1
Parfait, R1
Siska, G1
Winand, M1
Cockram, CS1
Richards, P1
Bax, RP1
Capel-Edwards, K1
Atkinson, RM1
Wheeldon, JM1
Pratt, DA1
Patterson, GG1
Harman, IW1
Foord, RD1
Odeh, M1
Oliven, A1
Cantu, TG1
Fantozzi, D1
Weiss, LG1
Cars, O1
Danielson, BG1
Grahnen, A1
Wikström, B1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Treatment of Febrile Infectious Disease Among Children in Hadera District Given the Final Diagnosis. Descriptive Study[NCT02313532]500 participants (Anticipated)Observational2015-01-31Not yet recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for cefuroxime and Kidney Diseases

ArticleYear
Renal parenchymal malacoplakia: a rare cause of ARF with a review of recent literature.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 2003, Volume: 41, Issue:6

    Topics: Acute Kidney Injury; Aged; Biopsy, Needle; Cefuroxime; Diagnosis, Differential; Drug Therapy, Combin

2003
The cephalosporins: activity and clinical use.
    Drugs, 1980, Volume: 20, Issue:2

    Topics: Cefaclor; Cefamandole; Cefatrizine; Cefazolin; Cefoxitin; Cefuroxime; Cephacetrile; Cephalexin; Ceph

1980

Trials

1 trial available for cefuroxime and Kidney Diseases

ArticleYear
Renal function in patients treated with tobramycin-cefuroxime or tobramycin-penicillin G.
    The Journal of antimicrobial chemotherapy, 1983, Volume: 12, Issue:6

    Topics: beta 2-Microglobulin; Cefuroxime; Cephalosporins; Chromium Radioisotopes; Drug Interactions; Drug Th

1983

Other Studies

13 other studies available for cefuroxime and Kidney Diseases

ArticleYear
Xanthogranulomatous pyelonephritis infiltrating the liver.
    Journal of pediatric surgery, 2008, Volume: 43, Issue:10

    Topics: Anti-Bacterial Agents; Cefuroxime; Cephalexin; Child; Clindamycin; Combined Modality Therapy; Divert

2008
Index of suspicion.
    Pediatrics in review, 2009, Volume: 30, Issue:9

    Topics: Abscess; Adolescent; Anti-Bacterial Agents; Brucellosis; Cefuroxime; Child; Doxycycline; Female; Gen

2009
Increasing antibiotic resistance among urinary tract isolates.
    Archives of disease in childhood, 2003, Volume: 88, Issue:5

    Topics: Adolescent; Anti-Bacterial Agents; Cefuroxime; Child; Ciprofloxacin; Drug Resistance, Bacterial; Esc

2003
Multiple abscesses caused by Gardnerella vaginalis in an immunocompetent man.
    The Journal of infection, 2005, Volume: 51, Issue:2

    Topics: Abdominal Abscess; Bacterial Infections; Cefuroxime; Empyema, Pleural; Gardnerella vaginalis; Humans

2005
Renal function during cefuroxime treatment in patients with pre-existing renal impairment.
    The Journal of antimicrobial chemotherapy, 1980, Volume: 6, Issue:5

    Topics: Cefuroxime; Cephaloridine; Cephalosporins; Edetic Acid; Furosemide; Gentamicins; Glomerular Filtrati

1980
Pharmacokinetics and clinical effects of cefuroxime in patients with severe renal insufficiency.
    European journal of clinical pharmacology, 1983, Volume: 24, Issue:3

    Topics: Aged; Cefuroxime; Cephalosporins; Creatinine; Female; Furosemide; Humans; Kidney Diseases; Kinetics;

1983
Pharmacokinetics of cefuroxime in normal and impaired renal function: comparison of high-pressure liquid chromatography and microbiological assays.
    Antimicrobial agents and chemotherapy, 1981, Volume: 19, Issue:3

    Topics: Adult; Biological Assay; Cefuroxime; Cephalosporins; Chromatography, High Pressure Liquid; Creatine;

1981
Pharmacokinetic study of cefuroxime in the elderly.
    British journal of clinical pharmacology, 1981, Volume: 12, Issue:6

    Topics: Aged; Cefuroxime; Cephalosporins; Female; Humans; Kidney Diseases; Kinetics; Lung Diseases; Male; Sp

1981
The safety of cefuroxime and gentamicin in patients with reduced renal function.
    Current medical research and opinion, 1980, Volume: 6, Issue:6

    Topics: Acute Kidney Injury; Adult; Aged; Bacteriuria; Cefuroxime; Cephalosporins; Drug Therapy, Combination

1980
Effect of timing of cefuroxime dosage on its protection of rats against gentamicin nephrotoxicity.
    Infection, 1980, Volume: 8, Issue:1

    Topics: Animals; Cefuroxime; Cephalosporins; Gentamicins; Kidney; Kidney Diseases; Male; Rats; Time Factors

1980
Acute brucellosis associated with massive proteinuria.
    Nephron, 1996, Volume: 72, Issue:4

    Topics: Acute Disease; Brucellosis; Cefuroxime; Cephalosporins; Diabetes Mellitus, Type 2; Female; Humans; K

1996
Cefuroxime dosage in renal failure.
    Annals of internal medicine, 1988, Dec-15, Volume: 109, Issue:12

    Topics: Cefuroxime; Cephalosporins; Humans; Kidney Diseases; Reference Books

1988
Pharmacokinetics of intravenous cefuroxime during intermittent and continuous arteriovenous hemofiltration.
    Clinical nephrology, 1988, Volume: 30, Issue:5

    Topics: Aged; Cefuroxime; Cephalosporins; Hemofiltration; Humans; Infusions, Intravenous; Kidney Diseases; M

1988