cefuroxime has been researched along with Infections, Prosthesis-Related in 28 studies
Cefuroxime: Broad-spectrum cephalosporin antibiotic resistant to beta-lactamase. It has been proposed for infections with gram-negative and gram-positive organisms, GONORRHEA, and HAEMOPHILUS.
cefuroxime : A 3-(carbamoyloxymethyl)cephalosporin compound having a 7-(2Z)-2-(furan-2-yl)-2-(methoxyimino)acetamido side chain.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Population pharmacokinetic modelling was performed in order to estimate pharmacokinetic parameters, and to assess the probability of attaining cefuroxime concentrations above clinically relevant minimal inhibitory concentrations (MICs) for 65% and 90% of the 8 h dosing interval." | 2.90 | Bone, subcutaneous tissue and plasma pharmacokinetics of cefuroxime in total knee replacement patients - a randomized controlled trial comparing continuous and short-term infusion. ( Bibby, BM; Birke-Sørensen, H; Bue, M; Fuursted, K; Hansen, P; Hardlei, TF; Søballe, K; Tøttrup, M, 2019) |
| "BMI ≥ 35 or weight ≥ 100 kg may serve as a cutoff for higher perioperative dosage of antibiotics." | 1.43 | Body mass and weight thresholds for increased prosthetic joint infection rates after primary total joint arthroplasty. ( Christofilopoulos, P; Harbarth, S; Hoffmeyer, P; Lübbeke, A; Miozzari, HH; Uçkay, I; Vu, D; Zingg, M, 2016) |
| "Early treatment of profound bilateral sensorineural hearing loss with cochlear implantation has become routine, resulting in an increased proportion of children implanted at younger ages." | 1.39 | The management of acute mastoiditis in children with cochlear implants: saving the device. ( Cushing, SL; Gordon, KA; James, AL; Osborn, HA; Papsin, BC, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (10.71) | 18.2507 |
| 2000's | 9 (32.14) | 29.6817 |
| 2010's | 13 (46.43) | 24.3611 |
| 2020's | 3 (10.71) | 2.80 |
| Authors | Studies |
|---|---|
| Chang, Y | 1 |
| Li, Y | 1 |
| Fan, T | 1 |
| Jiang, K | 1 |
| Lv, J | 1 |
| Huang, J | 1 |
| Stevoska, S | 1 |
| Behm-Ferstl, V | 1 |
| Zott, S | 1 |
| Stadler, C | 1 |
| Gotterbarm, T | 1 |
| Klasan, A | 1 |
| Tøttrup, M | 3 |
| Søballe, K | 3 |
| Bibby, BM | 1 |
| Hardlei, TF | 1 |
| Hansen, P | 1 |
| Fuursted, K | 2 |
| Birke-Sørensen, H | 1 |
| Bue, M | 3 |
| Veltman, ES | 1 |
| Lenguerrand, E | 1 |
| Moojen, DJF | 1 |
| Whitehouse, MR | 1 |
| Nelissen, RGHH | 1 |
| Blom, AW | 1 |
| Poolman, RW | 1 |
| Jensen, LK | 2 |
| Koch, J | 2 |
| Henriksen, NL | 1 |
| Hanberg, P | 2 |
| Jensen, HE | 2 |
| Osborn, HA | 1 |
| Cushing, SL | 1 |
| Gordon, KA | 1 |
| James, AL | 1 |
| Papsin, BC | 1 |
| Tornero, E | 2 |
| García-Ramiro, S | 1 |
| Martínez-Pastor, JC | 1 |
| Bori, G | 2 |
| Bosch, J | 2 |
| Morata, L | 1 |
| Sala, M | 1 |
| Basora, M | 1 |
| Mensa, J | 2 |
| Soriano, A | 2 |
| Lübbeke, A | 1 |
| Zingg, M | 1 |
| Vu, D | 1 |
| Miozzari, HH | 1 |
| Christofilopoulos, P | 1 |
| Uçkay, I | 1 |
| Harbarth, S | 1 |
| Hoffmeyer, P | 1 |
| Aalbæk, B | 1 |
| Capdevila, A | 1 |
| Navarro, M | 1 |
| Camacho, P | 1 |
| García, S | 1 |
| Hilker, L | 1 |
| von Woedtke, T | 1 |
| Weltmann, KD | 1 |
| Wollert, HG | 1 |
| Rasouli, JJ | 1 |
| Kopell, BH | 1 |
| Stefánsdóttir, A | 1 |
| Robertsson, O | 1 |
| W-Dahl, A | 1 |
| Kiernan, S | 1 |
| Gustafson, P | 1 |
| Lidgren, L | 1 |
| Tyllianakis, ME | 1 |
| Karageorgos, ACh | 1 |
| Marangos, MN | 1 |
| Saridis, AG | 1 |
| Lambiris, EE | 1 |
| Jenkins, PJ | 1 |
| Teoh, K | 1 |
| Simpson, PM | 1 |
| Dave, J | 1 |
| Simpson, AH | 1 |
| Breusch, S | 1 |
| Bhatia, R | 1 |
| Dalton, A | 1 |
| Richards, M | 1 |
| Hopkins, C | 1 |
| Aziz, T | 1 |
| Nandi, D | 1 |
| von der Brelie, C | 1 |
| Simon, A | 1 |
| Gröner, A | 1 |
| Molitor, E | 1 |
| Simon, M | 1 |
| Salavert, M | 1 |
| Navarro, V | 1 |
| Liu, HT | 1 |
| Chiu, FY | 3 |
| Chen, CM | 3 |
| Chen, TH | 1 |
| Hoad-Reddick, DA | 1 |
| Evans, CR | 1 |
| Norman, P | 1 |
| Stockley, I | 1 |
| Al-Maiyah, M | 1 |
| Hill, D | 1 |
| Bajwa, A | 1 |
| Slater, S | 1 |
| Patil, P | 1 |
| Port, A | 1 |
| Gregg, PJ | 1 |
| Byrne, AM | 1 |
| Morris, S | 1 |
| McCarthy, T | 1 |
| Quinlan, W | 1 |
| O'byrne, JM | 1 |
| Yinusa, W | 1 |
| Onche, II | 1 |
| Thanni, LO | 1 |
| Lynch, MJ | 1 |
| Scott, GM | 1 |
| Inglis, JA | 1 |
| Pryor, JP | 1 |
| Alvarez Ferrero, MM | 1 |
| Vree, TB | 1 |
| Baars, AM | 1 |
| Slooff, TJ | 1 |
| Lin, CF | 2 |
| Lo, WH | 2 |
| Chaung, TY | 1 |
| Wymenga, A | 1 |
| van Horn, J | 1 |
| Theeuwes, A | 1 |
| Muytjens, H | 1 |
| Slooff, T | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Single Shot Versus Multiple Shot Antibiotic Prophylaxis in Primary Joint Arthroplasty of the Hip and Knee, Comparison of Different Prophylaxis Regimes on the Risk of Revision for Infection[NCT03348254] | 242,179 participants (Actual) | Observational [Patient Registry] | 2016-04-30 | Completed | |||
| The Effect of Hair Removal on Intraoperative Contamination[NCT04256928] | 200 participants (Anticipated) | Interventional | 2020-02-15 | Not yet recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for cefuroxime and Infections, Prosthesis-Related
| Article | Year |
|---|---|
Second-Line Antibiotic Agents in Patient-Reported Penicillin or Cephalosporin Allergy Have No Negative Impact on Antibiotic Resistance After Hip and Knee Arthroplasty.
Topics: Anti-Bacterial Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Cefuroxime; | 2024 |
The incidence of deep brain stimulator hardware infection: the effect of change in antibiotic prophylaxis regimen and review of the literature.
Topics: Adult; Aged; Anti-Bacterial Agents; Antibiotic Prophylaxis; Cefuroxime; Cohort Studies; Deep Brain S | 2011 |
7 trials available for cefuroxime and Infections, Prosthesis-Related
| Article | Year |
|---|---|
Bone, subcutaneous tissue and plasma pharmacokinetics of cefuroxime in total knee replacement patients - a randomized controlled trial comparing continuous and short-term infusion.
Topics: Aged; Anti-Bacterial Agents; Antibiotic Prophylaxis; Arthroplasty, Replacement, Knee; Bone and Bones | 2019 |
Antibiotic prophylaxis in primary hip and knee arthroplasty: comparison between cefuroxime and two specific antistaphylococcal agents.
Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Arthroplasty, Replacement, Hip; Arthroplasty, | 2010 |
Outcome following deep wound contamination in cemented arthroplasty.
Topics: Anti-Bacterial Agents; Antibiotic Prophylaxis; Arthroplasty, Replacement, Hip; Arthroplasty, Replace | 2007 |
Short-term antibiotic prophylaxis in implant surgery: a comparison of three antibiotics.
Topics: Adolescent; Adult; Aged; Anti-Bacterial Agents; Antibiotic Prophylaxis; Ceftriaxone; Cefuroxime; Cip | 2007 |
Cefuroxime-impregnated cement at primary total knee arthroplasty in diabetes mellitus. A prospective, randomised study.
Topics: Aged; Aged, 80 and over; Antibiotic Prophylaxis; Arthroplasty, Replacement, Knee; Bone Cements; Cefu | 2001 |
Cefuroxime-impregnated cement in primary total knee arthroplasty: a prospective, randomized study of three hundred and forty knees.
Topics: Adult; Aged; Aged, 80 and over; Arthroplasty, Replacement, Knee; Bone Cements; Bone Diseases; Cefuro | 2002 |
Cefuroxime for prevention of postoperative coxitis. One versus three doses tested in a randomized multicenter study of 2,651 arthroplasties.
Topics: Aged; Cefuroxime; Dose-Response Relationship, Drug; Female; Hip Prosthesis; Humans; Infection Contro | 1992 |
19 other studies available for cefuroxime and Infections, Prosthesis-Related
| Article | Year |
|---|---|
Pathogenic bacteria characteristics and drug resistance in acute, delayed, and chronic periprosthetic joint infection: A retrospective analysis of 202 patients.
Topics: Anti-Bacterial Agents; Carbapenems; Cefuroxime; Clindamycin; Drug Resistance; Drug Resistance, Bacte | 2023 |
Similar risk of complete revision for infection with single-dose versus multiple-dose antibiotic prophylaxis in primary arthroplasty of the hip and knee: results of an observational cohort study in the Dutch Arthroplasty Register in 242,179 patients.
Topics: Anti-Bacterial Agents; Antibiotic Prophylaxis; Arthroplasty, Replacement, Hip; Arthroplasty, Replace | 2020 |
Suppurative Inflammation and Local Tissue Destruction Reduce the Penetration of Cefuroxime to Infected Bone Implant Cavities.
Topics: Animals; Anti-Bacterial Agents; Cefuroxime; Inflammation; Osteomyelitis; Prostheses and Implants; Pr | 2017 |
The management of acute mastoiditis in children with cochlear implants: saving the device.
Topics: Acute Disease; Amoxicillin-Potassium Clavulanate Combination; Anti-Bacterial Agents; Cefprozil; Cefu | 2013 |
Prophylaxis with teicoplanin and cefuroxime reduces the rate of prosthetic joint infection after primary arthroplasty.
Topics: Aged; Anti-Bacterial Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Cefuro | 2015 |
Body mass and weight thresholds for increased prosthetic joint infection rates after primary total joint arthroplasty.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Antibiotic Prophylaxis; Arthropla | 2016 |
Effects of Implant-Associated Osteomyelitis on Cefuroxime Bone Pharmacokinetics: Assessment in a Porcine Model.
Topics: Animals; Anti-Bacterial Agents; Area Under Curve; Cefuroxime; Female; Osteomyelitis; Prosthesis-Rela | 2016 |
Incidence and Risk Factors for Infection When Teicoplanin Is Included for Prophylaxis in Patients with Hip Fracture.
Topics: Aged, 80 and over; Anti-Bacterial Agents; Antibiotic Prophylaxis; Arthroplasty, Replacement, Hip; Bo | 2016 |
Cold atmospheric plasma: a new tool for the treatment of superficial driveline infections.
Topics: Aged; Anti-Bacterial Agents; Cefuroxime; Disinfection; Drug Resistance, Bacterial; Heart-Assist Devi | 2017 |
The Adjunctive Use of Vancomycin Powder Appears Safe and May Reduce the Incidence of Surgical-Site Infections After Deep Brain Stimulation Surgery.
Topics: Administration, Topical; Aged; Anti-Bacterial Agents; Antibiotic Prophylaxis; Burkholderia cepacia; | 2016 |
Inadequate timing of prophylactic antibiotics in orthopedic surgery. We can do better.
Topics: Anti-Bacterial Agents; Antibiotic Prophylaxis; Arthroplasty, Replacement, Knee; Cefuroxime; Clindamy | 2009 |
Clostridium difficile in patients undergoing primary hip and knee replacement.
Topics: Aged; Aged, 80 and over; Anti-Bacterial Agents; Antibiotic Prophylaxis; Arthroplasty, Replacement, H | 2010 |
Evaluation of an institutional guideline for the treatment of cerebrospinal fluid shunt-associated infections.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Bacterial Infections; Cefuroxime; | 2012 |
[Joint prosthesis infections: several comments].
Topics: Anti-Bacterial Agents; Antibiotic Prophylaxis; Arthroplasty, Replacement; Bacterial Infections; Bone | 2003 |
The combination of systemic antibiotics and antibiotics impregnated cement in primary total knee arthroplasty in patients of rheumatoid arthritis--evaluation of 60 knees.
Topics: Adult; Aged; Anti-Bacterial Agents; Arthritis, Rheumatoid; Arthroplasty, Replacement, Knee; Bone Cem | 2003 |
Is there a role for extended antibiotic therapy in a two-stage revision of the infected knee arthroplasty?
Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Arthroplasty, Replacement, Knee; Cefuroxime; | 2005 |
Bacterial contaminants and antibiotic prophylaxis in total hip arthroplasty.
Topics: Anti-Bacterial Agents; Antibiotic Prophylaxis; Arthroplasty, Replacement, Hip; Bacteria; Cefuroxime; | 2005 |
Reducing the loss of implants following penile prosthetic surgery.
Topics: Adult; Cefuroxime; Clinical Protocols; Erectile Dysfunction; Humans; Male; Middle Aged; Penile Prost | 1994 |
Plasma and bone concentrations of cefuroxime and flucloxacillin. Oral versus parenteral administration in 20 arthroplasties.
Topics: Administration, Oral; Aged; Aged, 80 and over; Bone and Bones; Cefuroxime; Female; Floxacillin; Hip | 1993 |