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cefuroxime and Gram-Positive Bacterial Infections

cefuroxime has been researched along with Gram-Positive Bacterial Infections in 16 studies

Cefuroxime: Broad-spectrum cephalosporin antibiotic resistant to beta-lactamase. It has been proposed for infections with gram-negative and gram-positive organisms, GONORRHEA, and HAEMOPHILUS.
cefuroxime : A 3-(carbamoyloxymethyl)cephalosporin compound having a 7-(2Z)-2-(furan-2-yl)-2-(methoxyimino)acetamido side chain.

Gram-Positive Bacterial Infections: Infections caused by bacteria that retain the crystal violet stain (positive) when treated by the gram-staining method.

Research Excerpts

ExcerptRelevanceReference
"A randomized, double-blind, double-dummy, three-arm parallel design, multicentre study was conducted among adult patients with acute exacerbation of chronic bronchitis (AECB) in order to compare the efficacy and safety of two different doses of levofloxacin with cefuroxime axetil."9.09Levofloxacin versus cefuroxime axetil in the treatment of acute exacerbation of chronic bronchitis: results of a randomized, double-blind study. ( Dolmann, A; Fiss, E; Maesen, FP; Shah, PM; Vetter, N; Wesch, R, 1999)
"A randomized, double-blind, double-dummy, three-arm parallel design, multicentre study was conducted among adult patients with acute exacerbation of chronic bronchitis (AECB) in order to compare the efficacy and safety of two different doses of levofloxacin with cefuroxime axetil."5.09Levofloxacin versus cefuroxime axetil in the treatment of acute exacerbation of chronic bronchitis: results of a randomized, double-blind study. ( Dolmann, A; Fiss, E; Maesen, FP; Shah, PM; Vetter, N; Wesch, R, 1999)
"Number of postoperative surgical site infections."2.72The value of chemoprophylaxis against Enterococcus species in elective cholecystectomy: a randomized study of cefuroxime vs ampicillin-sulbactam. ( Dervisoglou, A; Galanakis, N; Giamarellou, H; Giannakakis, P; Iordanou, C; Kanellakopoulou, K; Karampali, E; Liveranou, S; Ntasiou, P; Pierakakis, S; Pinis, S; Tsiodras, S, 2006)
"Cefuroxime axetil is a broad spectrum antibacterial agent with a pharmacokinetic profile that permits convenient twice-daily administration."2.41Cefuroxime axetil: an updated review of its use in the management of bacterial infections. ( Goa, KL; Ormrod, D; Scott, LJ, 2001)
"Cefuroxime was the initial empiric antimicrobial agent given for 66/76 of the patients and treatment outcome was favorable for 20/22 patients who received cefuroxime at least up to day 5."1.72Clinical and microbiological characterization of Aerococcus urinae bacteraemias at Helsinki metropolitan area, Finland. ( Grönroos, JO; Lehtola, L; Pakarinen, L; Pätäri-Sampo, A; Rantakokko-Jalava, K; Sihvonen, R; Turunen, M, 2022)
"Several studies on nuclear tissue from herniated discs have demonstrated the presence of low virulent anaerobic microorganisms, predominantly Propionibacterium acnes, in 7-53 % of patients."1.39Does nuclear tissue infected with bacteria following disc herniations lead to Modic changes in the adjacent vertebrae? ( Albert, HB; Busch, F; Elliott, T; Lambert, P; Manniche, C; Nørgaard, HS; Pedersen, MB; Rollason, J; Sorensen, JS; Vernallis, A; Worthington, T, 2013)
" Urine samples were taken every 2 h during the whole dosing interval of the particular antibiotic."1.33Urinary bactericidal activity of oral antibiotics against common urinary tract pathogens in an ex vivo model. ( Bedenic, B; Bubonja, M; Budimir, A; Topic, M, 2006)

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (25.00)18.2507
2000's6 (37.50)29.6817
2010's5 (31.25)24.3611
2020's1 (6.25)2.80

Authors

AuthorsStudies
Sihvonen, R1
Turunen, M1
Lehtola, L1
Pakarinen, L1
Grönroos, JO1
Rantakokko-Jalava, K1
Pätäri-Sampo, A1
Chatterjee, S1
Agrawal, D1
Siesing, PC1
Alva-Jørgensen, JP1
Brodersen, J1
Arpi, M1
Jensen, PE1
Guclu, E1
Pandita, A1
Murphy, C1
Albert, HB1
Lambert, P1
Rollason, J1
Sorensen, JS1
Worthington, T1
Pedersen, MB1
Nørgaard, HS1
Vernallis, A1
Busch, F1
Manniche, C1
Elliott, T1
Barnes, NP1
Hull, J1
Thomson, AH1
Bedenic, B1
Topic, M1
Budimir, A1
Bubonja, M1
Dervisoglou, A1
Tsiodras, S1
Kanellakopoulou, K1
Pinis, S1
Galanakis, N1
Pierakakis, S1
Giannakakis, P1
Liveranou, S1
Ntasiou, P1
Karampali, E1
Iordanou, C1
Giamarellou, H1
Kailasanathan, A1
Anderson, DF1
Munir, WM1
El Mallah, MK1
Janda, WM1
Tu, EY1
Erjavec, Z1
de Vries-Hospers, HG1
van Kamp, H1
van der Waaij, D1
Halie, MR1
Daenen, SM1
Suvorova, MP1
Iakovlev, SV1
Shakhova, TV1
Dvoretskiĭ, LI1
Shah, PM1
Maesen, FP1
Dolmann, A1
Vetter, N1
Fiss, E1
Wesch, R1
Scott, LJ1
Ormrod, D1
Goa, KL1
Chambers, ST1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Probiotics for Modic Changes: a Randomised Controlled Study to Elucidate the Effect of Probiotics on Vertebral Inflammatory End-plate Changes, So-called Type 1 Modic Changes[NCT03100266]94 participants (Actual)Interventional2016-01-14Completed
Subclinical Propionibacterium Acnes Infection Estimation in the Intervertebral Disc (SPInE-ID): a Prospective Cohort[NCT03158766]108 participants (Actual)Observational2017-05-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for cefuroxime and Gram-Positive Bacterial Infections

ArticleYear
Cefuroxime axetil: an updated review of its use in the management of bacterial infections.
    Drugs, 2001, Volume: 61, Issue:10

    Topics: Age Factors; Cefuroxime; Cephalosporins; Clinical Trials as Topic; Economics, Pharmaceutical; Female

2001
Which cephalosporin?
    The New Zealand medical journal, 1992, Dec-09, Volume: 105, Issue:947

    Topics: Bacterial Infections; Cefazolin; Cefoxitin; Cefuroxime; Cephalexin; Cephalosporins; Drug Costs; Gram

1992

Trials

5 trials available for cefuroxime and Gram-Positive Bacterial Infections

ArticleYear
Medical management of parapneumonic pleural disease.
    Pediatric pulmonology, 2005, Volume: 39, Issue:2

    Topics: Adolescent; Anti-Bacterial Agents; Cefuroxime; Chest Tubes; Child; Child, Preschool; Double-Blind Me

2005
The value of chemoprophylaxis against Enterococcus species in elective cholecystectomy: a randomized study of cefuroxime vs ampicillin-sulbactam.
    Archives of surgery (Chicago, Ill. : 1960), 2006, Volume: 141, Issue:12

    Topics: Ampicillin; Anti-Bacterial Agents; Cefuroxime; Chemoprevention; Cholecystectomy; Elective Surgical P

2006
Comparison of imipenem versus cefuroxime plus tobramycin as empirical therapy for febrile granulocytopenic patients and efficacy of vancomycin and aztreonam in case of failure.
    Scandinavian journal of infectious diseases, 1994, Volume: 26, Issue:5

    Topics: Adolescent; Adult; Aged; Agranulocytosis; Aztreonam; Cefuroxime; Drug Therapy, Combination; Female;

1994
[Program of empirical antibacterial therapy of community-acquired pneumonia].
    Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic], 1998, Volume: 43, Issue:7

    Topics: Administration, Oral; Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Anti-Infect

1998
Levofloxacin versus cefuroxime axetil in the treatment of acute exacerbation of chronic bronchitis: results of a randomized, double-blind study.
    The Journal of antimicrobial chemotherapy, 1999, Volume: 43, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Anti-Infective Agents; Bronchitis; Cefuroxime; Cephalosporins; Chron

1999

Other Studies

9 other studies available for cefuroxime and Gram-Positive Bacterial Infections

ArticleYear
Clinical and microbiological characterization of Aerococcus urinae bacteraemias at Helsinki metropolitan area, Finland.
    European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 2022, Volume: 41, Issue:5

    Topics: Aerococcus; Aged; Anti-Bacterial Agents; Bacteremia; Ceftriaxone; Cefuroxime; Disease Susceptibility

2022
5% cefuroxime as an alternative to 5% cefazolin in the treatment of Gram-positive bacterial keratitis.
    Indian journal of ophthalmology, 2018, Volume: 66, Issue:7

    Topics: Anti-Bacterial Agents; Cefazolin; Cefuroxime; Dose-Response Relationship, Drug; Eye Infections, Bact

2018
Rising incidence of Enterococcus species in microbiological specimens from orthopedic patients correlates to increased use of cefuroxime: a study concentrating on tissue samples.
    Acta orthopaedica, 2013, Volume: 84, Issue:3

    Topics: Anti-Bacterial Agents; Cefuroxime; Cross Infection; Denmark; Drug Utilization; Enterococcus; Gram-Po

2013
Rising incidence of Enterococcus species in microbiological specimens from orthopedic patients correlates to increased use of cefuroxime.
    Acta orthopaedica, 2014, Volume: 85, Issue:2

    Topics: Anti-Bacterial Agents; Cefuroxime; Enterococcus; Gram-Positive Bacterial Infections; Humans; Orthope

2014
Microbial keratitis in Waikato, New Zealand.
    Clinical & experimental ophthalmology, 2011, Volume: 39, Issue:5

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Cefuroxime; Child; Child, Preschool; Corneal Ulcer; Eye

2011
Does nuclear tissue infected with bacteria following disc herniations lead to Modic changes in the adjacent vertebrae?
    European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, 2013, Volume: 22, Issue:4

    Topics: Adult; Anti-Bacterial Agents; Bone Diseases; Cefuroxime; Cohort Studies; Edema; Female; Follow-Up St

2013
Does nuclear tissue infected with bacteria following disc herniations lead to Modic changes in the adjacent vertebrae?
    European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, 2013, Volume: 22, Issue:4

    Topics: Adult; Anti-Bacterial Agents; Bone Diseases; Cefuroxime; Cohort Studies; Edema; Female; Follow-Up St

2013
Does nuclear tissue infected with bacteria following disc herniations lead to Modic changes in the adjacent vertebrae?
    European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, 2013, Volume: 22, Issue:4

    Topics: Adult; Anti-Bacterial Agents; Bone Diseases; Cefuroxime; Cohort Studies; Edema; Female; Follow-Up St

2013
Does nuclear tissue infected with bacteria following disc herniations lead to Modic changes in the adjacent vertebrae?
    European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, 2013, Volume: 22, Issue:4

    Topics: Adult; Anti-Bacterial Agents; Bone Diseases; Cefuroxime; Cohort Studies; Edema; Female; Follow-Up St

2013
Urinary bactericidal activity of oral antibiotics against common urinary tract pathogens in an ex vivo model.
    Chemotherapy, 2006, Volume: 52, Issue:6

    Topics: Acetamides; Administration, Oral; Adult; Amoxicillin; Amoxicillin-Potassium Clavulanate Combination;

2006
Infectious crystalline keratopathy caused by Gemella haemolysans.
    Cornea, 2007, Volume: 26, Issue:5

    Topics: Anti-Bacterial Agents; Cefuroxime; Colony Count, Microbial; Corneal Diseases; Drug Therapy, Combinat

2007
Gemella haemolysans infectious crystalline keratopathy.
    Cornea, 2008, Volume: 27, Issue:2

    Topics: Anti-Bacterial Agents; Cefuroxime; Colony Count, Microbial; Corneal Diseases; Drug Therapy, Combinat

2008