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cefuroxime and Gonorrhea

cefuroxime has been researched along with Gonorrhea in 34 studies

Cefuroxime: Broad-spectrum cephalosporin antibiotic resistant to beta-lactamase. It has been proposed for infections with gram-negative and gram-positive organisms, GONORRHEA, and HAEMOPHILUS.
cefuroxime : A 3-(carbamoyloxymethyl)cephalosporin compound having a 7-(2Z)-2-(furan-2-yl)-2-(methoxyimino)acetamido side chain.

Gonorrhea: Acute infectious disease characterized by primary invasion of the urogenital tract. The etiologic agent, NEISSERIA GONORRHOEAE, was isolated by Neisser in 1879.

Research Excerpts

ExcerptRelevanceReference
"A randomized, multicenter, investigator-blind trial was conducted to compare the efficacies of cefuroxime axetil and ciprofloxacin for treatment of patients with uncomplicated gonorrhea caused by penicillinase-producing Neisseria gonorrhoeae (PPNG)."9.08Comparison of single-dose cefuroxime axetil with ciprofloxacin in treatment of uncomplicated gonorrhea caused by penicillinase-producing and non-penicillinase-producing Neisseria gonorrhoeae strains. ( Collins, JJ; Giguere, GC; Hook, EW; McCormack, WM; Mussari, KL; Rompalo, A; Schwebke, JR; Thorpe, EM, 1996)
"A patient who contracted urethritis from a beta-lactamase-producing strain of Neisseria gonorrhoeae was successfully treated with the cephalosporin derivative cefuroxime."7.66Cefuroxime treatment of urethritis caused by a beta-lactamase-producing strain of Neisseria gonorrhoeae. ( Bergström, S; Burman, LA; Elmros, T; Holm, S; Kjellberg, E; Norlander, L; Normark, S, 1980)
"Twenty-seven episodes of gonorrhea occurring in children less than 15 years of age were treated with an intramuscular injection of cefuroxime, 25 mg/kg."7.66Cefuroxime therapy of gonorrhea and coinfection with Chlamydia trachomatis in children. ( Nelson, JD; Patamasucon, P; Rettig, PJ, 1981)
"A randomized, multicenter, investigator-blind trial was conducted to compare the efficacies of cefuroxime axetil and ciprofloxacin for treatment of patients with uncomplicated gonorrhea caused by penicillinase-producing Neisseria gonorrhoeae (PPNG)."5.08Comparison of single-dose cefuroxime axetil with ciprofloxacin in treatment of uncomplicated gonorrhea caused by penicillinase-producing and non-penicillinase-producing Neisseria gonorrhoeae strains. ( Collins, JJ; Giguere, GC; Hook, EW; McCormack, WM; Mussari, KL; Rompalo, A; Schwebke, JR; Thorpe, EM, 1996)
"Four hundred sixty-six female patients were enrolled in a randomized study that compared the clinical efficacies of single oral doses of cefuroxime axetil and amoxicillin with probenecid in the treatment of uncomplicated gonorrhea."5.06Clinical comparison of single-oral-dose cefuroxime axetil and amoxicillin with probenecid for uncomplicated gonococcal infections in women. ( Baddour, LM; Cocchetto, DM; Gibbs, RS; Mertz, G; Noble, RC, 1989)
"5 g) was compared with amoxicillin (3 g), both given as a single oral dose combined with probenecid (1 g) for the treatment of uncomplicated gonorrhea."5.06Comparative clinical efficacy of single oral doses of cefuroxime axetil and amoxicillin in uncomplicated gonococcal infections. ( Fong, IW; Hinton, NA; Linton, W; Simbul, M, 1986)
"A patient who contracted urethritis from a beta-lactamase-producing strain of Neisseria gonorrhoeae was successfully treated with the cephalosporin derivative cefuroxime."3.66Cefuroxime treatment of urethritis caused by a beta-lactamase-producing strain of Neisseria gonorrhoeae. ( Bergström, S; Burman, LA; Elmros, T; Holm, S; Kjellberg, E; Norlander, L; Normark, S, 1980)
"Twenty-seven episodes of gonorrhea occurring in children less than 15 years of age were treated with an intramuscular injection of cefuroxime, 25 mg/kg."3.66Cefuroxime therapy of gonorrhea and coinfection with Chlamydia trachomatis in children. ( Nelson, JD; Patamasucon, P; Rettig, PJ, 1981)
"Cefuroxime has a second-generation cephalosporin spectrum of activity similar to cefamandole."2.36Cefuroxime: antimicrobial activity, Pharmacology, and clinical efficacy. ( LeFrock, JL; Smith, BR, 1983)
"Cefuroxime was as effective as spectinomycin in the treatment of infections due to penicillinase-producing strains of Neisseria gonorrhoeae (PPNG) and was significantly more effective than 4."1.27Cefuroxime, thiamphenicol, spectinomycin, and penicillin G in uncomplicated infections due to penicillinase-producing strains of Neisseria gonorrhoeae. ( Calubiran, OV; Crisologo, LB; de Jesus, I; Torres, CA; Tupasi, TE, 1983)

Research

Studies (34)

TimeframeStudies, this research(%)All Research%
pre-199027 (79.41)18.7374
1990's5 (14.71)18.2507
2000's1 (2.94)29.6817
2010's1 (2.94)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Gong, Z1
Lai, W1
Liu, M1
Hua, Z1
Sun, Y1
Xu, Q1
Xia, Y1
Zhao, Y1
Xie, X1
Hegde, V1
Smith, G1
Choi, J1
Pagliarini, S1
Das, R1
Bingham, JS1
Ridgway, G1
Oriel, JD1
Stolz, E3
Ong, L1
van Joost, T2
Michel, MF3
Normark, S1
Elmros, T1
Norlander, L1
Kjellberg, E1
Holm, S1
Burman, LA1
Bergström, S1
Tupasi, TE1
Crisologo, LB2
Torres, CA2
Calubiran, OV2
de Jesus, I1
Smith, BR1
LeFrock, JL1
Ruckdeschel, G1
Neubert, U1
Korting, HC1
Lindberg, M1
Ringertz, O1
Sandström, E1
Tupasi, T1
Bello, CS1
Fakunle, YM1
Acred, P1
Grujic, P1
Ryan, DM1
Xerri, L1
Orsolini, P1
Erani, E1
Nayyar, KC1
Lossick, JG1
Thompson, SE1
Smeltzer, MP1
Timmis, AD1
Crofts, MA1
Metcalfe, J1
Monaghan, MJ1
Sharp, J1
Jackson, G1
Patamasucon, P1
Rettig, PJ1
Nelson, JD1
Zhang, B1
Liu, Y1
Wang, J1
Wang, B1
Thorpe, EM1
Schwebke, JR1
Hook, EW1
Rompalo, A1
McCormack, WM1
Mussari, KL1
Giguere, GC1
Collins, JJ1
Mesa, JJ1
Lin, SS1
Catalano, J1
Deutch, LS1
Crabbé, F1
Tchupo, JP1
Manchester, T1
Gruber-Tapsoba, T1
Mugrditchian, D1
Timyan, J1
Goodridge, G1
Cheta, C1
Laga, M1
Dallabetta, G1
Kinghorn, GR1
Spencer, RC2
Smith, TK1
Woolley, PD1
Patel, R1
Robinson, AJ2
Baddour, LM1
Gibbs, RS1
Mertz, G1
Cocchetto, DM1
Noble, RC1
Chitwarakorn, A1
Ariyarit, C1
Panikabutra, K1
Buateing, A1
Biddle, J1
Thompson, S1
Brown, S1
Talbot, MD1
Das, RP1
Jones, K1
Timmins, DJ1
Glatt, AE1
Fong, IW1
Linton, W1
Simbul, M1
Hinton, NA1
Yinnon, AM1
Klutstein, M1
Balkin, J1
Jephcott, AE1
Egglestone, SI1
Schift, R1
van Ulsen, J1
Ansink-Schipper, MC2
Woudstra, RK1
Wanas, TM1
Williams, PE1
Gottlieb, A1
Mills, J1
van Klingeren, B1
Huikeshoven, H1
Woudstra, R1
Dessens-Kroon, M1

Reviews

2 reviews available for cefuroxime and Gonorrhea

ArticleYear
Cefuroxime: antimicrobial activity, Pharmacology, and clinical efficacy.
    Therapeutic drug monitoring, 1983, Volume: 5, Issue:2

    Topics: Cefuroxime; Cephalosporins; Enterobacteriaceae; Gonorrhea; Humans; Kinetics; Lung Diseases; Meningit

1983
Second-generation cephalosporins.
    Hospital practice (Office ed.), 1986, Mar-15, Volume: 21, Issue:3

    Topics: Bacterial Infections; Bacteroides Infections; Cefamandole; Cefazolin; Cefonicid; Cefoxitin; Cefuroxi

1986

Trials

10 trials available for cefuroxime and Gonorrhea

ArticleYear
Treatment of non-complicated urogenital, rectal and oropharyngeal gonorrhoea with intramuscular cefotaxime 1.0 g or cefuroxime 1.5 g.
    The Journal of antimicrobial chemotherapy, 1984, Volume: 14 Suppl B

    Topics: beta-Lactamases; Cefotaxime; Cefuroxime; Cephalosporins; Female; Gonorrhea; Humans; Male; Neisseria

1984
Comparison of cefuroxime and penicillin in the treatment of uncomplicated gonorrhea.
    Antimicrobial agents and chemotherapy, 1982, Volume: 22, Issue:3

    Topics: Cefuroxime; Cephalosporins; Clinical Trials as Topic; Double-Blind Method; Female; Gonorrhea; Humans

1982
Comparison of single-dose cefuroxime axetil with ciprofloxacin in treatment of uncomplicated gonorrhea caused by penicillinase-producing and non-penicillinase-producing Neisseria gonorrhoeae strains.
    Antimicrobial agents and chemotherapy, 1996, Volume: 40, Issue:12

    Topics: Adolescent; Adult; Anti-Infective Agents; Cefuroxime; Cephalosporins; Cervix Uteri; Ciprofloxacin; F

1996
Comparative study of cefuroxime axetil and procaine penicillin in the treatment of uncomplicated gonorrhoea.
    International journal of STD & AIDS, 1990, Volume: 1, Issue:4

    Topics: Administration, Oral; Cefuroxime; Cervix Uteri; Female; Follow-Up Studies; Gonorrhea; Humans; Inject

1990
Clinical comparison of single-oral-dose cefuroxime axetil and amoxicillin with probenecid for uncomplicated gonococcal infections in women.
    Antimicrobial agents and chemotherapy, 1989, Volume: 33, Issue:6

    Topics: Adolescent; Adult; Amoxicillin; Cefuroxime; Cephalosporins; Drug Therapy, Combination; Female; Gonor

1989
Treating gonococcal infections resistant to penicillin in Bangkok: comparison of cefuroxime and spectinomycin.
    Genitourinary medicine, 1985, Volume: 61, Issue:5

    Topics: Adolescent; Adult; Cefuroxime; Cephalosporins; Clinical Trials as Topic; Drug Therapy, Combination;

1985
Cefuroxime axetil to treat gonorrhea.
    Genitourinary medicine, 1988, Volume: 64, Issue:6

    Topics: Ampicillin; Cefuroxime; Cephalosporins; Clinical Trials as Topic; Drug Therapy, Combination; Female;

1988
Comparative clinical efficacy of single oral doses of cefuroxime axetil and amoxicillin in uncomplicated gonococcal infections.
    Antimicrobial agents and chemotherapy, 1986, Volume: 30, Issue:2

    Topics: Amoxicillin; Cefuroxime; Cephalosporins; Drug Therapy, Combination; Female; Gonorrhea; Humans; Male;

1986
Comparison of oral treatment of uncomplicated urogenital and rectal gonorrhoea with cefuroxime axetil ester or clavulanic acid potentiated amoxycillin (Augmentin).
    Genitourinary medicine, 1986, Volume: 62, Issue:5

    Topics: Administration, Oral; Adolescent; Adult; Amoxicillin; Amoxicillin-Potassium Clavulanate Combination;

1986
Cefuroxime axetil for treatment of uncomplicated gonorrhea.
    Antimicrobial agents and chemotherapy, 1986, Volume: 30, Issue:2

    Topics: Adolescent; Adult; Aged; Amoxicillin; Cefuroxime; Cephalosporins; Drug Therapy, Combination; Gonorrh

1986

Other Studies

22 other studies available for cefuroxime and Gonorrhea

ArticleYear
Novel Genes Related to Ceftriaxone Resistance Found among Ceftriaxone-Resistant Neisseria gonorrhoeae Strains Selected In Vitro.
    Antimicrobial agents and chemotherapy, 2016, Volume: 60, Issue:4

    Topics: Amino Acid Sequence; Anti-Bacterial Agents; ATP-Binding Cassette Transporters; Ceftriaxone; Cefuroxi

2016
A case of gonococcal kerato-conjunctivitis mimicking orbital cellulitis.
    Acta ophthalmologica Scandinavica, 2005, Volume: 83, Issue:4

    Topics: Adult; Ceftriaxone; Cefuroxime; Cellulitis; Diagnosis, Differential; Drug Therapy, Combination; Eye

2005
A comparative trial of cefuroxime axetil and ampicillin plus probenecid in the treatment of acute gonococcal infection.
    Journal of chemotherapy (Florence, Italy), 1989, Volume: 1, Issue:4 Suppl

    Topics: Acute Disease; Ampicillin; Anti-Bacterial Agents; Cefuroxime; Clinical Trials as Topic; Drug Therapy

1989
Cefuroxime treatment of urethritis caused by a beta-lactamase-producing strain of Neisseria gonorrhoeae.
    Acta dermato-venereologica, 1980, Volume: 60, Issue:3

    Topics: Adult; beta-Lactamases; Cefuroxime; Cephalosporins; Drug Resistance, Microbial; Gonorrhea; Humans; M

1980
Cefuroxime, thiamphenicol, spectinomycin, and penicillin G in uncomplicated infections due to penicillinase-producing strains of Neisseria gonorrhoeae.
    The British journal of venereal diseases, 1983, Volume: 59, Issue:3

    Topics: Adolescent; Adult; Cefuroxime; Cephalosporins; Female; Gonorrhea; Humans; Microbial Sensitivity Test

1983
Distribution of auxotypes and correlation to antibiotic susceptibility of 169 recent clinical Neisseria gonorrhoeae isolates from Munich.
    Archives of dermatological research, 1983, Volume: 275, Issue:6

    Topics: Cefuroxime; Germany, West; Gonorrhea; Humans; Kanamycin; Microbial Sensitivity Tests; Neisseria gono

1983
Treatment of pharyngeal gonorrhea due to beta-lactamase-producing gonococci.
    The British journal of venereal diseases, 1982, Volume: 58, Issue:2

    Topics: Cefuroxime; Cephalosporins; Female; Gonorrhea; Humans; Male; Microbial Sensitivity Tests; Neisseria

1982
Comparison of spectinomycin, cefuroxime, thiamphenicol, and penicillin G in the treatment of uncomplicated gonococcal infections in women.
    The Journal of infectious diseases, 1982, Volume: 145, Issue:4

    Topics: Anti-Bacterial Agents; beta-Lactamases; Cefuroxime; Female; Gonorrhea; Humans; Neisseria gonorrhoeae

1982
Single dose treatment of acute gonorrhoea with Cefuroxime: experience from Zaria, Nigeria.
    East African medical journal, 1983, Volume: 60, Issue:2

    Topics: Acute Disease; Cefuroxime; Cephalosporins; Gonorrhea; Humans; Nigeria

1983
In vitro activity of cefuroxime against Treponema pallidum and Neisseria gonorrhoeae.
    The Journal of antimicrobial chemotherapy, 1980, Volume: 6, Issue:3

    Topics: Ampicillin; Animals; Cefuroxime; Cephalosporins; Female; Ferric Compounds; Gonorrhea; Male; Mice; Ne

1980
Antibiotic sensitivities of gonococci isolated in Rotterdam and results of treatment with cefuroxime.
    The British journal of venereal diseases, 1980, Volume: 56, Issue:4

    Topics: Anti-Bacterial Agents; Cefuroxime; Cephalosporins; Female; Gonorrhea; Humans; Male; Microbial Sensit

1980
Gonococcal endocarditis with penicillin-induced bone marrow hypoplasia. Role of echocardiography.
    JAMA, 1981, Aug-07, Volume: 246, Issue:6

    Topics: Adolescent; Agranulocytosis; Bone Marrow; Cefuroxime; Echocardiography; Endocarditis, Bacterial; Fem

1981
Cefuroxime therapy of gonorrhea and coinfection with Chlamydia trachomatis in children.
    Pediatrics, 1981, Volume: 68, Issue:4

    Topics: Adolescent; Anus Diseases; Cefuroxime; Cephalosporins; Child; Child, Preschool; Chlamydia Infections

1981
[Clinical observation of oral cefuroxime axetil for treating acute gonorrhoea].
    Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae, 1995, Volume: 17, Issue:4

    Topics: Acute Disease; Administration, Oral; Adult; Cefuroxime; Cephalosporins; Female; Gonorrhea; Humans; M

1995
Sternoclavicular gonococcal arthritis in an adolescent girl.
    Orthopedics, 1998, Volume: 21, Issue:1

    Topics: Adolescent; Arthritis, Infectious; Biopsy, Needle; Ceftriaxone; Cefuroxime; Cephalosporins; Female;

1998
Prepackaged therapy for urethritis: the "MSTOP" experience in Cameroon.
    Sexually transmitted infections, 1998, Volume: 74, Issue:4

    Topics: Anti-Bacterial Agents; Cameroon; Cefuroxime; Chlamydia Infections; Condoms; Doxycycline; Gonorrhea;

1998
The use of aztreonam in the treatment of uncomplicated gonorrhoea.
    Current medical research and opinion, 1985, Volume: 9, Issue:9

    Topics: Aztreonam; Cefuroxime; Female; Gonorrhea; Humans; Injections, Intramuscular; Male; Microbial Sensiti

1985
Drug-resistant gonorrhea infections in Canada. Plasma-mediated resistance.
    Bulletin of the Pan American Health Organization, 1986, Volume: 20, Issue:1

    Topics: Anti-Bacterial Agents; Cefoxitin; Cefuroxime; Gonorrhea; Humans; Microbial Sensitivity Tests; Neisse

1986
Gonococcal endocarditis: a rare disease.
    Israel journal of medical sciences, 1988, Volume: 24, Issue:8

    Topics: Adult; Aortic Valve; Cefuroxime; Endocarditis, Bacterial; Gonorrhea; Humans; Male; Neisseria gonorrh

1988
In vitro activity of temocillin against Neisseria gonorrhoeae including penicillinase-producing strains.
    Drugs, 1985, Volume: 29 Suppl 5

    Topics: Amoxicillin; Cefuroxime; Dose-Response Relationship, Drug; Gonorrhea; Humans; In Vitro Techniques; M

1985
Oral cefuroxime axetil compared with oral ampicillin in treating acute uncomplicated gonorrhoea.
    Genitourinary medicine, 1986, Volume: 62, Issue:4

    Topics: Adolescent; Adult; Ampicillin; Cefuroxime; Cephalosporins; Female; Follow-Up Studies; Gonorrhea; Hum

1986
Relation between nutritional requirements and susceptibilities to antibiotics of strains of Neisseria gonorrhoeae from pharyngeal and anogenital sites.
    Genitourinary medicine, 1985, Volume: 61, Issue:1

    Topics: Aminopeptidases; Anal Canal; Anti-Bacterial Agents; Cefuroxime; Erythromycin; Genitalia; Gonorrhea;

1985