Page last updated: 2024-10-24

cefuroxime and Escherichia coli Infections

cefuroxime has been researched along with Escherichia coli Infections in 40 studies

Cefuroxime: Broad-spectrum cephalosporin antibiotic resistant to beta-lactamase. It has been proposed for infections with gram-negative and gram-positive organisms, GONORRHEA, and HAEMOPHILUS.
cefuroxime : A 3-(carbamoyloxymethyl)cephalosporin compound having a 7-(2Z)-2-(furan-2-yl)-2-(methoxyimino)acetamido side chain.

Escherichia coli Infections: Infections with bacteria of the species ESCHERICHIA COLI.

Research Excerpts

ExcerptRelevanceReference
" The objectives of this study were to assess the clinical efficacy of intravenous cefuroxime as an empirical antibiotic for the treatment of hospitalized women with acute pyelonephritis (APN) caused by Escherichia coli."7.83Use of cefuroxime for women with community-onset acute pyelonephritis caused by cefuroxime-susceptible or -resistant Escherichia coli. ( Chang, UI; Kim, HW; Wie, SH, 2016)
"To present the outcomes of prophylaxis of postoperative endophthalmitis following cataract surgery with intracameral Cefuroxime."7.75[Prophylaxis of postoperative endophthalmitis with intracameral cefuroxime: a five years' experience]. ( Arteta, M; De la Rosa, G; Díez, MR; Girón, C; Pascual, R, 2009)
"The following results were obtained from the fundamental and clinical studies of cefuroxime, a new synthetic cephalosporin, in pediatric patients with purulent meningitis."7.66[Fundamental and clinical studies of cefuroxime in pediatric purulent meningitis (author's transl)]. ( Hori, M; Kumagai, K; Kurosu, Y; Toyonaga, Y, 1980)
"Cefuroxime axetil is an effective antimicrobial for uncomplicated pediatric UTIs."6.67Two-day therapy with cefuroxime axetil is effective for urinary tract infections in children. ( Collins, JJ; Feld, LG; Kornberg, AE; Mydlow, PK; Sherin, K; Veiga, P, 1994)
" The objectives of this study were to assess the clinical efficacy of intravenous cefuroxime as an empirical antibiotic for the treatment of hospitalized women with acute pyelonephritis (APN) caused by Escherichia coli."3.83Use of cefuroxime for women with community-onset acute pyelonephritis caused by cefuroxime-susceptible or -resistant Escherichia coli. ( Chang, UI; Kim, HW; Wie, SH, 2016)
"Nitrofurantoin has been used for decades for the treatment of urinary tract infections (UTIs), but clinically significant resistance in Escherichia coli is uncommon."3.80An in vitro deletion in ribE encoding lumazine synthase contributes to nitrofurantoin resistance in Escherichia coli. ( Adriaenssens, N; Coenen, S; Godycki-Cwirko, M; Goossens, H; Harbarth, S; Kowalczyk, A; Lammens, C; Malhotra-Kumar, S; Stewardson, A; Vervoort, J; Xavier, BB, 2014)
"To present the outcomes of prophylaxis of postoperative endophthalmitis following cataract surgery with intracameral Cefuroxime."3.75[Prophylaxis of postoperative endophthalmitis with intracameral cefuroxime: a five years' experience]. ( Arteta, M; De la Rosa, G; Díez, MR; Girón, C; Pascual, R, 2009)
"The following results were obtained from the fundamental and clinical studies of cefuroxime, a new synthetic cephalosporin, in pediatric patients with purulent meningitis."3.66[Fundamental and clinical studies of cefuroxime in pediatric purulent meningitis (author's transl)]. ( Hori, M; Kumagai, K; Kurosu, Y; Toyonaga, Y, 1980)
"Cefuroxime axetil is an effective antimicrobial for uncomplicated pediatric UTIs."2.67Two-day therapy with cefuroxime axetil is effective for urinary tract infections in children. ( Collins, JJ; Feld, LG; Kornberg, AE; Mydlow, PK; Sherin, K; Veiga, P, 1994)
"Renal parenchymal malacoplakia is a rare cause of acute renal failure."2.42Renal parenchymal malacoplakia: a rare cause of ARF with a review of recent literature. ( Chan, KW; Kung, WH; Li, R; Tam, VK, 2003)
"Cefuroxime was chosen as the PBP-3-active antibiotic and tobramycin represented the aminoglycosides."1.56Mode of bacterial killing affects the inflammatory response and associated organ dysfunctions in a porcine E. coli intensive care sepsis model. ( Larsson, A; Lipcsey, M; Maudsdotter, L; Sjölin, J; Skorup, P, 2020)
"Emphysematous cystitis is a rare disease with a high mortality rate."1.43[Emphysematous cystitis]. ( Haferkamp, A; Hüsch, T; Müller, T; Rheinboldt, V; Thalhammer, A, 2016)
"All animals developed severe sepsis/septic shock."1.40Beneficial antimicrobial effect of the addition of an aminoglycoside to a β-lactam antibiotic in an E. coli porcine intensive care severe sepsis model. ( Castegren, M; Jonsson, AB; Larsson, A; Lipcsey, M; Maudsdotter, L; Sjölin, J; Skorup, P, 2014)
" The population was characterized by a population pharmacokinetic model, and distributions of CLcr and body weight were reflective of the target group."1.35Estimation of cefuroxime dosage using pharmacodynamic targets, MIC distributions, and minimization of a risk function. ( Cars, O; Jönsson, S; Karlsson, MO; Viberg, A, 2008)
" Using pharmacokinetic parameters of the plasma concentrations in vivo and those of the Hill equation the corresponding time course of ER was calculated and by integration with respect to time (0tERdt), an estimate was obtained of the effect on bacteria."1.28Antibacterial activity of four cephalosporins in an experimental infection in relation to in vitro effect and pharmacokinetics. ( Brus-Weijer, L; Krul, AM; Mattie, H; van Dokkum, AM; van Strijen, E, 1990)

Research

Studies (40)

TimeframeStudies, this research(%)All Research%
pre-19906 (15.00)18.7374
1990's7 (17.50)18.2507
2000's13 (32.50)29.6817
2010's11 (27.50)24.3611
2020's3 (7.50)2.80

Authors

AuthorsStudies
Thønnings, S1
Jensen, KS1
Nielsen, NB1
Skjønnemand, M1
Hansen, DS1
Lange, KHW1
Frimodt-Møller, N2
Demirci-Duarte, S1
Unalan-Altintop, T1
Eser, OK1
Cakar, A1
Altun, B1
Sancak, B1
Gur, D1
Skorup, P3
Maudsdotter, L3
Lipcsey, M3
Larsson, A3
Sjölin, J3
Bosch-Nicolau, P1
Falcó, V1
Viñado, B1
Andreu, A1
Len, O1
Almirante, B1
Pigrau, C1
Tano, E1
Castegren, M2
Kõljalg, S1
Truusalu, K1
Stsepetova, J1
Pai, K1
Vainumäe, I1
Sepp, E1
Mikelsaar, M1
Jonsson, AB1
Vervoort, J1
Xavier, BB1
Stewardson, A1
Coenen, S1
Godycki-Cwirko, M1
Adriaenssens, N1
Kowalczyk, A1
Lammens, C1
Harbarth, S1
Goossens, H1
Malhotra-Kumar, S1
Can, F1
Azap, OK1
Seref, C1
Ispir, P1
Arslan, H1
Ergonul, O1
Süzük, S1
Kaşkatepe, B1
Avcıküçük, H1
Aksaray, S1
Başustaoğlu, A1
Chang, UI1
Kim, HW1
Wie, SH1
Hüsch, T1
Rheinboldt, V1
Thalhammer, A1
Müller, T1
Haferkamp, A1
Ilhan, G1
Verit Atmaca, FF1
Kaya, A1
Ergin, AH1
Gökmen Karasu, AF1
Turfan, M1
Taskinen, S1
Giordano, S1
Rintala, R1
Viberg, A1
Cars, O1
Karlsson, MO1
Jönsson, S1
Díez, MR1
De la Rosa, G1
Pascual, R1
Girón, C1
Arteta, M1
Källman, O1
Giske, CG1
Samuelsen, Ø1
Wretlind, B1
Kalin, M1
Olsson-Liljequist, B1
Zhao, H1
Kang, XL1
Chen, XL1
Wang, JX1
Le, Y1
Shen, ZG1
Chen, JF1
Ayoub, T1
Arshad, I1
Donnellan, I1
Cullen, IM1
Manecksha, RP1
McCullagh, E1
Ahmad, S1
O'Kelly, F1
Flynn, R1
McDermott, TE1
Murphy, P1
Grainger, R1
Fennell, JP1
Thornhill, JA1
Tam, VK1
Kung, WH1
Li, R1
Chan, KW1
Bayrak, O1
Cimentepe, E1
Inegöl, I1
Atmaca, AF1
Duvan, CI1
Koç, A1
Turhan, NO1
Peltola, V1
Svedström, E1
Waris, M1
Heikkinen, T1
Ruuskanen, O1
Toyonaga, Y1
Kurosu, Y1
Kumagai, K1
Hori, M1
Venuti, M1
Orlando, R1
Nassuato, G1
Martines, D1
Lirussi, F1
Okolicsanyi, L1
George, J1
Chakravarthy, S1
John, GT1
Jacob, CK1
Arstila, T1
Auvinen, H1
Huovinen, P1
Kornberg, AE1
Sherin, K1
Veiga, P1
Mydlow, PK1
Collins, JJ1
Feld, LG1
Hasan, S1
Hall, FC1
Maidment, G1
Hvidberg, H1
Struve, C1
Krogfelt, KA1
Christensen, N1
Rasmussen, SN1
Orrett, FA1
Shurland, SM1
Cronberg, S1
Banke, S1
Bergman, B1
Boman, H1
Eilard, T1
Elbel, E1
Hugo-Persson, M1
Johansson, E1
Kuylenstierna, N1
Lanbeck, P1
Lindblom, A1
Paulsen, O1
Schönbeck, C1
Walder, M1
Wieslander, P1
Nicolás Torralba, JA1
Bañón Pérez, V1
Valdelvira Nadal, P1
López Cubillana, P1
Server Pastor, G1
Pérez Albacete, M1
Cooper, J1
Raeburn, A1
Brumfitt, W1
Hamilton-Miller, JM1
Slack, RC1
Mattie, H1
van Dokkum, AM1
Brus-Weijer, L1
Krul, AM1
van Strijen, E1
Beale, AS2
Gisby, J2
Sutherland, R1
Wijma, J1
Kauer, FM1
van Saene, HK1
van de Wiel, HB1
Janssens, J1
Uri, JV1
Phillips, L1
Pitkin, DH1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Tolerance and Efficacy of Amiklin Administration During Nosocomial Infections Complicating COVID-19 in the ICU[NCT05511129]1,053 participants (Actual)Observational2022-05-12Active, not recruiting
Epidemiology of ST131 in Besançon University Hospital[NCT02853708]300 participants (Actual)Observational2015-06-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for cefuroxime and Escherichia coli Infections

ArticleYear
Renal parenchymal malacoplakia: a rare cause of ARF with a review of recent literature.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 2003, Volume: 41, Issue:6

    Topics: Acute Kidney Injury; Aged; Biopsy, Needle; Cefuroxime; Diagnosis, Differential; Drug Therapy, Combin

2003
Bilateral emphysematous pyelonephritis responding to nonsurgical management.
    American journal of nephrology, 1995, Volume: 15, Issue:2

    Topics: Cefuroxime; Ciprofloxacin; Diabetic Nephropathies; Drug Therapy, Combination; Emphysema; Escherichia

1995

Trials

6 trials available for cefuroxime and Escherichia coli Infections

ArticleYear
Is single-dose fosfomycin trometamol a good alternative for asymptomatic bacteriuria in the second trimesterof pregnancy?
    International urogynecology journal and pelvic floor dysfunction, 2007, Volume: 18, Issue:5

    Topics: Adult; Age Factors; Anti-Bacterial Agents; Bacteriuria; Cefuroxime; Drug Administration Schedule; Es

2007
Two-day therapy with cefuroxime axetil is effective for urinary tract infections in children.
    American journal of nephrology, 1994, Volume: 14, Issue:3

    Topics: Administration, Oral; Cefuroxime; Child; Child, Preschool; Colony Count, Microbial; Drug Administrat

1994
Fewer bacterial relapses after oral treatment with norfloxacin than with ceftibuten in acute pyelonephritis initially treated with intravenous cefuroxime.
    Scandinavian journal of infectious diseases, 2001, Volume: 33, Issue:5

    Topics: Acute Disease; Administration, Oral; Adult; Aged; Aged, 80 and over; Anti-Infective Agents; Ceftibut

2001
Comparative efficacy and tolerability of cephradine and cefuroxime axetil in the treatment of acute dysuria and/or frequency in general practice.
    The British journal of clinical practice, 1992,Spring, Volume: 46, Issue:1

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Bacteriuria; Cefuroxime; Cephradine; Escherichia coli In

1992
Definition of urinary tract infection and assessment of efficacy in drug trials--a laboratory perspective.
    Infection, 1992, Volume: 20 Suppl 3

    Topics: Bacteriuria; Cefuroxime; Colony Count, Microbial; Escherichia coli Infections; Female; Humans; Mass

1992
Antibiotics and suction drainage as prophylaxis in vaginal and abdominal hysterectomy.
    Obstetrics and gynecology, 1987, Volume: 70, Issue:3 Pt 1

    Topics: Abscess; Bacteroides Infections; Cefuroxime; Cephalosporins; Cystitis; Escherichia coli Infections;

1987

Other Studies

32 other studies available for cefuroxime and Escherichia coli Infections

ArticleYear
Cefuroxime pharmacokinetics and pharmacodynamics for intravenous dosage regimens with 750 mg or 1500 mg doses in healthy young volunteers.
    Journal of medical microbiology, 2020, Volume: 69, Issue:3

    Topics: Adult; Anti-Bacterial Agents; Cefuroxime; Escherichia coli; Escherichia coli Infections; Female; Hea

2020
Prevalence of O25b-ST131 clone and fosfomycin resistance in urinary Escherichia coli isolates and their relation to CTX-M determinant.
    Diagnostic microbiology and infectious disease, 2020, Volume: 98, Issue:1

    Topics: Amikacin; Anti-Bacterial Agents; beta-Lactamases; Ceftriaxone; Cefuroxime; Ciprofloxacin; DNA, Bacte

2020
Mode of bacterial killing affects the inflammatory response and associated organ dysfunctions in a porcine E. coli intensive care sepsis model.
    Critical care (London, England), 2020, 11-14, Volume: 24, Issue:1

    Topics: Animals; Cefuroxime; Disease Models, Animal; Endotoxins; Escherichia coli; Escherichia coli Infectio

2020
A Cohort Study of Risk Factors That Influence Empirical Treatment of Patients with Acute Pyelonephritis.
    Antimicrobial agents and chemotherapy, 2017, Volume: 61, Issue:12

    Topics: Acute Disease; Adult; Aged; Amoxicillin-Potassium Clavulanate Combination; Anti-Bacterial Agents; Ce

2017
Dynamics of Endotoxin, Inflammatory Variables, and Organ Dysfunction After Treatment With Antibiotics in an Escherichia coli Porcine Intensive Care Sepsis Model.
    Critical care medicine, 2018, Volume: 46, Issue:7

    Topics: Animals; Anti-Bacterial Agents; Cefuroxime; Disease Models, Animal; Drug Therapy, Combination; Endot

2018
The Escherichia coli phylogenetic group B2 with integrons prevails in childhood recurrent urinary tract infections.
    APMIS : acta pathologica, microbiologica, et immunologica Scandinavica, 2014, Volume: 122, Issue:5

    Topics: Anti-Bacterial Agents; Bacterial Typing Techniques; Cefotaxime; Cefuroxime; Child; Child, Preschool;

2014
Beneficial antimicrobial effect of the addition of an aminoglycoside to a β-lactam antibiotic in an E. coli porcine intensive care severe sepsis model.
    PloS one, 2014, Volume: 9, Issue:2

    Topics: Animals; Anti-Bacterial Agents; Bacteremia; Bacterial Load; Cefuroxime; Critical Care; Disease Model

2014
An in vitro deletion in ribE encoding lumazine synthase contributes to nitrofurantoin resistance in Escherichia coli.
    Antimicrobial agents and chemotherapy, 2014, Volume: 58, Issue:12

    Topics: Aerobiosis; Anaerobiosis; Anti-Bacterial Agents; Base Sequence; Cefuroxime; Drug Resistance, Bacteri

2014
Emerging Escherichia coli O25b/ST131 clone predicts treatment failure in urinary tract infections.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2015, Feb-15, Volume: 60, Issue:4

    Topics: Aged; Anti-Bacterial Agents; Bacterial Typing Techniques; Cefuroxime; Ciprofloxacin; Cohort Studies;

2015
[The comparison of antibiotic susceptibilities of uropathogenic Escherichia coli isolates in transition from CLSI to EUCAST].
    Mikrobiyoloji bulteni, 2015, Volume: 49, Issue:4

    Topics: Amikacin; Ampicillin; Anti-Bacterial Agents; Bacteriuria; Cefuroxime; Ciprofloxacin; Disk Diffusion

2015
Use of cefuroxime for women with community-onset acute pyelonephritis caused by cefuroxime-susceptible or -resistant Escherichia coli.
    The Korean journal of internal medicine, 2016, Volume: 31, Issue:1

    Topics: Administration, Intravenous; Aged; Anti-Bacterial Agents; Cefuroxime; Community-Acquired Infections;

2016
[Emphysematous cystitis].
    Der Urologe. Ausg. A, 2016, Volume: 55, Issue:5

    Topics: Aged; Breast Neoplasms; Cefuroxime; Cystitis; Diabetes Complications; Diabetes Mellitus, Type 2; Dis

2016
Risk factors and microbiology of wound infections following cesarean delivery: Experience of a single institution.
    Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy, 2016, Volume: 22, Issue:10

    Topics: Abdomen; Adult; Anti-Bacterial Agents; Antibiotic Prophylaxis; Cefazolin; Cefuroxime; Cesarean Secti

2016
Xanthogranulomatous pyelonephritis infiltrating the liver.
    Journal of pediatric surgery, 2008, Volume: 43, Issue:10

    Topics: Anti-Bacterial Agents; Cefuroxime; Cephalexin; Child; Clindamycin; Combined Modality Therapy; Divert

2008
Estimation of cefuroxime dosage using pharmacodynamic targets, MIC distributions, and minimization of a risk function.
    Journal of clinical pharmacology, 2008, Volume: 48, Issue:11

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Cefuroxime; Creatinine; Drug Admi

2008
[Prophylaxis of postoperative endophthalmitis with intracameral cefuroxime: a five years' experience].
    Archivos de la Sociedad Espanola de Oftalmologia, 2009, Volume: 84, Issue:2

    Topics: Anterior Chamber; Anti-Bacterial Agents; Antibiotic Prophylaxis; Cefuroxime; Corynebacterium Infecti

2009
Interplay of efflux, impermeability, and AmpC activity contributes to cefuroxime resistance in clinical, non-ESBL-producing isolates of Escherichia coli.
    Microbial drug resistance (Larchmont, N.Y.), 2009, Volume: 15, Issue:2

    Topics: Anti-Bacterial Agents; Bacterial Proteins; beta-Lactamase Inhibitors; beta-Lactamases; Boronic Acids

2009
Antibacterial activities of amorphous cefuroxime axetil ultrafine particles prepared by high gravity antisolvent precipitation (HGAP).
    Pharmaceutical development and technology, 2009, Volume: 14, Issue:5

    Topics: Animals; Anti-Bacterial Agents; Cefuroxime; Chemical Precipitation; Drug Compounding; Escherichia co

2009
Concurrent emphysematous cholecystitis and emphysematous cystitis in a non-diabetic patient.
    British journal of hospital medicine (London, England : 2005), 2009, Volume: 70, Issue:10

    Topics: Aged, 80 and over; Anti-Infective Agents; Cefuroxime; Cystitis; Drug Therapy, Combination; Emphysema

2009
An 11-year analysis of the prevalent uropathogens and the changing pattern of Escherichia coli antibiotic resistance in 38,530 community urinary tract infections, Dublin 1999-2009.
    Irish journal of medical science, 2013, Volume: 182, Issue:1

    Topics: Adolescent; Adult; Amoxicillin-Potassium Clavulanate Combination; Ampicillin; Anti-Bacterial Agents;

2013
Pulmonary abscess of viral-bacterial etiology in a neonate.
    European journal of pediatrics, 2007, Volume: 166, Issue:12

    Topics: Anti-Infective Agents; Cefuroxime; Cephalexin; Escherichia coli Infections; Female; Humans; Infant,

2007
[Fundamental and clinical studies of cefuroxime in pediatric purulent meningitis (author's transl)].
    The Japanese journal of antibiotics, 1980, Volume: 33, Issue:12

    Topics: Cefuroxime; Cephalosporins; Child, Preschool; Drug Evaluation; Escherichia coli Infections; Female;

1980
[Therapeutic effectiveness of metossimine associated with an aminoglycoside in a case of severe gram-negative sepsis].
    La Clinica terapeutica, 1981, Apr-15, Volume: 97, Issue:1

    Topics: Cefuroxime; Cephalosporins; Diabetes Complications; Drug Therapy, Combination; Escherichia coli Infe

1981
Beta-lactam resistance among Escherichia coli and Klebsiella species blood culture isolates in Finnish hospitals. Finnish Study Group for Antimicrobial Resistance.
    European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 1994, Volume: 13, Issue:6

    Topics: Bacteremia; beta-Lactam Resistance; Cefuroxime; Cephalosporins; Drug Utilization; Escherichia coli;

1994
The Dambusters: a case of cerebrospinal and urinary obstruction.
    Journal of the Royal Society of Medicine, 1993, Volume: 86, Issue:11

    Topics: Aged; Catheterization; Cefuroxime; Ciprofloxacin; Escherichia coli Infections; Humans; Hydrocephalus

1993
Development of a long-term ascending urinary tract infection mouse model for antibiotic treatment studies.
    Antimicrobial agents and chemotherapy, 2000, Volume: 44, Issue:1

    Topics: Animals; Anti-Bacterial Agents; Cefuroxime; Disease Models, Animal; Dose-Response Relationship, Drug

2000
Prevalence of resistance to antimicrobials of Escherichia coli isolates from clinical sources at a private hospital in Trinidad.
    Japanese journal of infectious diseases, 2001, Volume: 54, Issue:2

    Topics: Amoxicillin-Potassium Clavulanate Combination; Ampicillin; Anti-Bacterial Agents; Cefuroxime; Cephal

2001
[Abscess of seminal vesicle: conservative treatment].
    Archivos espanoles de urologia, 2001, Volume: 54, Issue:5

    Topics: Abscess; Cefuroxime; Cephalosporins; Escherichia coli Infections; Genital Diseases, Male; Humans; Ma

2001
Antibacterial activity of four cephalosporins in an experimental infection in relation to in vitro effect and pharmacokinetics.
    The Journal of infectious diseases, 1990, Volume: 162, Issue:3

    Topics: Agranulocytosis; Animals; Cefamandole; Ceftazidime; Ceftriaxone; Cefuroxime; Cephalosporins; Disease

1990
Inactivation of cefuroxime and cefotaxime by Bacteroides fragilis in vitro, and its influence on the treatment of an experimental Escherichia coli/Bacteroides fragilis mixed infection.
    The Journal of antimicrobial chemotherapy, 1989, Volume: 24, Issue:1

    Topics: Amoxicillin; Animals; Bacteroides fragilis; Bacteroides Infections; beta-Lactamases; Cefotaxime; Cef

1989
Efficacy of amoxycillin/clavulanic acid in experimental Bacteroides fragilis/Escherichia coli mixed infections.
    The Journal of antimicrobial chemotherapy, 1988, Volume: 21, Issue:4

    Topics: Amoxicillin; Amoxicillin-Potassium Clavulanate Combination; Ampicillin; Animals; Anti-Bacterial Agen

1988
Comparative laboratory studies on alpha-methoxyimino furyl- and phenylacetamido cephalosporins: structure-activity relationships.
    Acta microbiologica Hungarica, 1986, Volume: 33, Issue:2

    Topics: Animals; Bacteria; Cefazolin; Cefuroxime; Cephalosporins; Escherichia coli Infections; Half-Life; Ki

1986