cefuroxime has been researched along with Drug Hypersensitivity in 33 studies
Cefuroxime: Broad-spectrum cephalosporin antibiotic resistant to beta-lactamase. It has been proposed for infections with gram-negative and gram-positive organisms, GONORRHEA, and HAEMOPHILUS.
cefuroxime : A 3-(carbamoyloxymethyl)cephalosporin compound having a 7-(2Z)-2-(furan-2-yl)-2-(methoxyimino)acetamido side chain.
Drug Hypersensitivity: Immunologically mediated adverse reactions to medicinal substances used legally or illegally.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A sixty-one year old female with a past history of asthma was admitted to the emergency department because of vertigo, nausea, vomiting, chest pain and generalized erythema after taking an oral dose of cefuroxime axetil." | 7.75 | Kounis Syndrome secondary to cefuroxime axetil use in an asthmatic patient. ( Ayhan, E; Güvenç, TS; Ilhan, E; Poyraz, E; Soylu, O, 2009) |
| "Specific serum IgE antibodies to several cephalosporins were monitored in a 52-year-old man after a selective systemic anaphylaxis attributable to cefuroxime, who showed a good tolerance to penicillin V during a single-blind, placebo-controlled challenge." | 7.71 | Boosted IgE response after anaphylaxis reaction to cefuroxime with cross-reactivity with cefotaxime. ( Blanca, M; Florido, JF; Mayorga, C; Quiralte, J; Sáenz de San Pedro, B; Torres, MJ, 2002) |
| "Cefuroxime is a second-generation cephalosporin antibiotic that causes immediate hypersensitivity reactions, ranging from mild urticaria to severe anaphylactic shock." | 5.51 | Cefuroxime-induced anaphylaxis with prominent central nervous system manifestations: A case report. ( Gu, J; Liu, S; Zhi, Y, 2019) |
| "A sixty-one year old female with a past history of asthma was admitted to the emergency department because of vertigo, nausea, vomiting, chest pain and generalized erythema after taking an oral dose of cefuroxime axetil." | 3.75 | Kounis Syndrome secondary to cefuroxime axetil use in an asthmatic patient. ( Ayhan, E; Güvenç, TS; Ilhan, E; Poyraz, E; Soylu, O, 2009) |
| "76 years) who had presented with anaphylaxis or urticaria-angioedema within the first 60 minutes after administration of Amoxicillin (54/67), Penicillin G (7/67), Cefuroxime (5/67) or Cefazoline (1/67)." | 3.73 | Antigen specific quantification of sulfidoleukotrienes in patients allergic to Betalactam antibiotics. ( Antépara, I; De Weck, AL; Gamboa, PM; García-Avilés, C; Jauregui, I; Sanz, ML; Urrutia, I, 2005) |
| "Specific serum IgE antibodies to several cephalosporins were monitored in a 52-year-old man after a selective systemic anaphylaxis attributable to cefuroxime, who showed a good tolerance to penicillin V during a single-blind, placebo-controlled challenge." | 3.71 | Boosted IgE response after anaphylaxis reaction to cefuroxime with cross-reactivity with cefotaxime. ( Blanca, M; Florido, JF; Mayorga, C; Quiralte, J; Sáenz de San Pedro, B; Torres, MJ, 2002) |
| "Intracameral cefuroxime 1 mg appears safe in terms of local toxicity." | 2.70 | Prophylactic intracameral cefuroxime. Evaluation of safety and kinetics in cataract surgery. ( Montan, PG; Rylander, M; Setterquist, H; Wejde, G; Zetterström, C, 2002) |
| "Cefuroxime is a second-generation cephalosporin antibiotic that causes immediate hypersensitivity reactions, ranging from mild urticaria to severe anaphylactic shock." | 1.51 | Cefuroxime-induced anaphylaxis with prominent central nervous system manifestations: A case report. ( Gu, J; Liu, S; Zhi, Y, 2019) |
| "Mastocytosis is a heterogeneous group of diseases characterized by excessive proliferation and accumulation of mast cells--in one or more organs." | 1.42 | [Anaphylaxis as part of a clinical diagnosis of mastocytosi - case demonstration]. ( Czarnobilska, E; Sacha, M; Stobiecki, M, 2015) |
| "Cefuroxime appeared to be a safe alternative in beta-lactam-allergic patients after testing." | 1.36 | Safety of cefuroxime as an alternative in patients with a proven hypersensitivity to penicillins: a DAHD cohort survey. ( Arnoux, B; Bousquet, PJ; Bousquet-Rouanet, L; Caimmi, S; Demoly, P; Galéra, C, 2010) |
| " Three of 35 evaluated patients were withdrawn from therapy because of adverse events, one of which was a drug-related hypersensitivity reaction." | 1.28 | The safety, efficacy, and tolerability of cefuroxime axetil suspension in infants and children receiving previous intravenous antibiotic therapy. ( Nahata, MC; Ossi, MJ; Powell, DA; Powell, NE, 1991) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (9.09) | 18.7374 |
| 1990's | 6 (18.18) | 18.2507 |
| 2000's | 10 (30.30) | 29.6817 |
| 2010's | 9 (27.27) | 24.3611 |
| 2020's | 5 (15.15) | 2.80 |
| Authors | Studies |
|---|---|
| Mahiat, C | 1 |
| Robaye, S | 1 |
| Levecq, L | 1 |
| Dumesnil, D | 1 |
| Sohy, C | 1 |
| Stevoska, S | 1 |
| Behm-Ferstl, V | 1 |
| Zott, S | 1 |
| Stadler, C | 1 |
| Gotterbarm, T | 1 |
| Klasan, A | 1 |
| Stirbienė, N | 1 |
| Rudzevičienė, O | 1 |
| Peña-Mendizabal, E | 1 |
| Morais, S | 1 |
| Maquieira, Á | 1 |
| Sexton, ME | 1 |
| Kuruvilla, ME | 1 |
| Wolf, FA | 1 |
| Lynde, GC | 1 |
| Wiley, Z | 1 |
| Aurich, S | 1 |
| Schüürmann, M | 1 |
| Simon, JC | 1 |
| Treudler, R | 1 |
| Merget, R | 1 |
| Sander, I | 1 |
| Fartasch, M | 1 |
| van Kampen, V | 1 |
| Röseler, S | 1 |
| Merk, H | 1 |
| Wurpts, G | 1 |
| Raulf, M | 1 |
| Brüning, T | 1 |
| Gu, J | 1 |
| Liu, S | 1 |
| Zhi, Y | 1 |
| Song, Z | 1 |
| Fu, W | 1 |
| Zhou, L | 1 |
| Christiansen, IS | 1 |
| Krøigaard, M | 1 |
| Mosbech, H | 1 |
| Skov, PS | 1 |
| Poulsen, LK | 1 |
| Garvey, LH | 1 |
| Promelle, V | 1 |
| Jany, B | 1 |
| Drimbea, A | 1 |
| Jezraoui, P | 1 |
| Milazzo, S | 1 |
| Stobiecki, M | 1 |
| Sacha, M | 1 |
| Czarnobilska, E | 1 |
| Biteker, M | 1 |
| Duran, NE | 1 |
| Biteker, FS | 1 |
| Gündüz, S | 1 |
| Gökdeniz, T | 1 |
| Kaya, H | 1 |
| Astarcioğlu, MA | 1 |
| Ozkan, M | 1 |
| Ilhan, E | 1 |
| Güvenç, TS | 1 |
| Poyraz, E | 1 |
| Ayhan, E | 1 |
| Soylu, O | 1 |
| Varela Losada, S | 1 |
| González de la Cuesta, C | 1 |
| Alvarez-Eire, MG | 1 |
| González González, C | 1 |
| Caimmi, S | 1 |
| Galéra, C | 1 |
| Bousquet-Rouanet, L | 1 |
| Arnoux, B | 1 |
| Demoly, P | 1 |
| Bousquet, PJ | 1 |
| Murat, SN | 1 |
| Karasu, BB | 1 |
| Ornek, E | 1 |
| Akdemir, R | 1 |
| Sáenz de San Pedro, B | 1 |
| Mayorga, C | 2 |
| Torres, MJ | 1 |
| Florido, JF | 1 |
| Quiralte, J | 1 |
| Blanca, M | 2 |
| Abraham, D | 1 |
| Saltoun, CA | 1 |
| Barton, LL | 1 |
| García-Avilés, C | 1 |
| Sanz, ML | 1 |
| Gamboa, PM | 1 |
| Urrutia, I | 1 |
| Antépara, I | 1 |
| Jauregui, I | 1 |
| De Weck, AL | 2 |
| Mitra, A | 1 |
| McElvanney, A | 1 |
| Schneider, CH | 1 |
| Weinstein, AJ | 1 |
| Marcos Bravo, C | 1 |
| Luna Ortiz, I | 1 |
| González Vázquez, R | 1 |
| Hattori, H | 1 |
| Yamaguchi, F | 1 |
| Wagai, N | 1 |
| Kato, M | 1 |
| Nomura, M | 1 |
| Romano, A | 2 |
| Quaratino, D | 1 |
| Venuti, A | 2 |
| Venemalm, L | 1 |
| Leong, CL | 1 |
| Thiruventhiran, T | 1 |
| Montan, PG | 1 |
| Wejde, G | 1 |
| Setterquist, H | 1 |
| Rylander, M | 1 |
| Zetterström, C | 1 |
| Pietrantonio, F | 1 |
| Di Fonso, M | 1 |
| Powell, DA | 1 |
| Nahata, MC | 1 |
| Powell, NE | 1 |
| Ossi, MJ | 1 |
| VanArsdel, PP | 1 |
| Yarbrough, JA | 1 |
| Moffitt, JE | 1 |
| Brown, DA | 1 |
| Stafford, CT | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Intracameral Levofloxacin (0.5%) Versus Intracameral Cefuroxime (1mg/0.1ml) Effect on Corneal Endothelial Cell Count and Morphology in Uneventful Phacoemulsification[NCT04212078] | Phase 1/Phase 2 | 138 participants (Anticipated) | Interventional | 2019-07-29 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for cefuroxime and Drug Hypersensitivity
| Article | Year |
|---|---|
Second-Line Antibiotic Agents in Patient-Reported Penicillin or Cephalosporin Allergy Have No Negative Impact on Antibiotic Resistance After Hip and Knee Arthroplasty.
Topics: Anti-Bacterial Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Cefuroxime; | 2024 |
The cephalosporins: activity and clinical use.
Topics: Cefaclor; Cefamandole; Cefatrizine; Cefazolin; Cefoxitin; Cefuroxime; Cephacetrile; Cephalexin; Ceph | 1980 |
1 trial available for cefuroxime and Drug Hypersensitivity
| Article | Year |
|---|---|
Prophylactic intracameral cefuroxime. Evaluation of safety and kinetics in cataract surgery.
Topics: Aged; Aged, 80 and over; Antibiotic Prophylaxis; Aqueous Humor; Cefuroxime; Cell Count; Cephalospori | 2002 |
30 other studies available for cefuroxime and Drug Hypersensitivity
| Article | Year |
|---|---|
Anaphylactic Shock Following Cataract Surgery: A Documented Intracameral Cefuroxime Allergy.
Topics: Anaphylaxis; Anti-Bacterial Agents; Cataract; Cataract Extraction; Cefuroxime; Drug Hypersensitivity | 2022 |
Repeated anaphylaxis to cefuroxime in teenager and cross-reactivity to cephalosporins due to R2 side chain.
Topics: Adolescent; Anaphylaxis; Anti-Bacterial Agents; Cefuroxime; Cephalosporins; Cross Reactions; Drug Hy | 2020 |
Neo-antigens for the serological diagnosis of IgE-mediated drug allergic reactions to antibiotics cephalosporin, carbapenem and monobactam.
Topics: Anti-Bacterial Agents; Aztreonam; beta-Lactams; Carbapenems; Cefotaxime; Ceftriaxone; Cefuroxime; Ce | 2020 |
Anatomy of a successful stewardship intervention: Improving perioperative prescribing in penicillin-allergic patients.
Topics: Anti-Bacterial Agents; Carbapenems; Cefazolin; Cefuroxime; Cephalosporins; Drug Hypersensitivity; Hu | 2022 |
Anaphylactic shock caused by intradermal testing with cefuroxime.
Topics: Anaphylaxis; Cefuroxime; Diagnosis, Differential; Drug Hypersensitivity; Female; Humans; Hypersensit | 2017 |
Occupational generalized urticaria and anaphylaxis after inhalation of cefuroxime in a nurse.
Topics: Anaphylaxis; Anti-Bacterial Agents; Cefuroxime; Drug Hypersensitivity; Female; Humans; Inhalation Ex | 2018 |
Cefuroxime-induced anaphylaxis with prominent central nervous system manifestations: A case report.
Topics: Anaphylaxis; Anti-Bacterial Agents; Cefuroxime; Central Nervous System Diseases; Drug Hypersensitivi | 2019 |
Cefuroxime, levofloxacin, esomeprazole, and bismuth as first-line therapy for eradicating Helicobacter pylori in patients allergic to penicillin.
Topics: Antacids; Anti-Bacterial Agents; Bismuth; Breath Tests; Cefuroxime; China; Drug Hypersensitivity; Dr | 2019 |
Clinical and diagnostic features of perioperative hypersensitivity to cefuroxime.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Cefuroxime; Drug Hypersensitivity | 2015 |
Tolerability of intracameral cefuroxime during cataract surgery in case of penicillin allergy.
Topics: Aged; Anti-Bacterial Agents; Antibiotic Prophylaxis; Cataract Extraction; Cefuroxime; Drug Hypersens | 2015 |
[Anaphylaxis as part of a clinical diagnosis of mastocytosi - case demonstration].
Topics: Adult; Anaphylaxis; Anti-Inflammatory Agents, Non-Steroidal; Cefuroxime; Drug Hypersensitivity; Fema | 2015 |
Kounis syndrome secondary to cefuroxime-axetil use in an octogenarian.
Topics: Aged, 80 and over; Angina, Unstable; Anti-Bacterial Agents; Cefuroxime; Coronary Vasospasm; Diagnosi | 2008 |
Kounis Syndrome secondary to cefuroxime axetil use in an asthmatic patient.
Topics: Acute Coronary Syndrome; Anaphylaxis; Anti-Bacterial Agents; Asthma; Cefuroxime; Coronary Angiograph | 2009 |
Immediate-type allergic reaction to cefuroxime: cross-reactivity with other cephalosporins, and good tolerance to ceftazidime.
Topics: Ceftazidime; Cefuroxime; Cross Reactions; Drug Hypersensitivity; Exanthema; Female; Humans; Molecula | 2009 |
Safety of cefuroxime as an alternative in patients with a proven hypersensitivity to penicillins: a DAHD cohort survey.
Topics: Adult; Anti-Bacterial Agents; Cefuroxime; Cohort Studies; Cross Reactions; Data Collection; Drug Hyp | 2010 |
Cefuroxime-axetil induced allergic angina: an insight into classification management of Kounis syndrome.
Topics: Angina Pectoris; Anti-Bacterial Agents; Cefuroxime; Coronary Angiography; Coronary Restenosis; Drug | 2011 |
Boosted IgE response after anaphylaxis reaction to cefuroxime with cross-reactivity with cefotaxime.
Topics: Anaphylaxis; Cefotaxime; Cefuroxime; Cephalosporins; Cross Reactions; Drug Hypersensitivity; Humans; | 2002 |
Facial swelling and eosinophilia in a 44-year-old woman.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Angioedema; Cefuroxime; Cetirizine; Diagnosis, Diffe | 2002 |
Cefuroxime-induced immune hemolysis.
Topics: Anemia, Hemolytic; Anti-Bacterial Agents; Cefuroxime; Drug Hypersensitivity; Humans; Pneumonia, Bact | 2004 |
Antigen specific quantification of sulfidoleukotrienes in patients allergic to Betalactam antibiotics.
Topics: Amoxicillin; Anaphylaxis; Angioedema; Anti-Bacterial Agents; Cefazolin; Cefuroxime; Drug Hypersensit | 2005 |
Prophylactic subconjunctival cefuroxime during cataract surgery in patients with a penicillin allergy.
Topics: Adult; Aged; Aged, 80 and over; Antibiotic Prophylaxis; Cataract Extraction; Cefuroxime; Conjunctiva | 2006 |
Allergic and immunological aspects of therapy with cefotaxime and other cephalosporins.
Topics: Animals; Cefotaxime; Cefuroxime; Cephalosporins; Cross Reactions; Drug Hypersensitivity; Guinea Pigs | 1980 |
Hypersensitivity to cefuroxime with good tolerance to other betalactams.
Topics: Anti-Bacterial Agents; Cefuroxime; Cross Reactions; Drug Hypersensitivity; Drug Tolerance; Humans; M | 1995 |
An assessment of antigenic potential of beta-lactam antibiotics, low molecular weight drugs, using guinea pig models.
Topics: Anaphylaxis; Animals; Anti-Bacterial Agents; Antigens; Cefmenoxime; Cefmetazole; Ceftazidime; Cefuro | 1997 |
Selective type-1 hypersensitivity to cefuroxime.
Topics: Cefuroxime; Cephalosporins; Drug Hypersensitivity; Female; Humans; Immunoglobulin E; Middle Aged; Sk | 1998 |
Cefuroxime-induced acute renal failure.
Topics: Acute Kidney Injury; Adult; Cefuroxime; Cephalosporins; Drug Hypersensitivity; Humans; Kidney; Male | 2000 |
Delayed hypersensitivity to cefuroxime.
Topics: Cefuroxime; Drug Eruptions; Drug Hypersensitivity; Female; Humans; Hypersensitivity, Delayed; Middle | 1992 |
The safety, efficacy, and tolerability of cefuroxime axetil suspension in infants and children receiving previous intravenous antibiotic therapy.
Topics: Anti-Bacterial Agents; Cefuroxime; Cellulitis; Child; Child, Preschool; Drug Hypersensitivity; Drug | 1991 |
Allergy to cephalosporins.
Topics: Adult; Anaphylaxis; Cefuroxime; Cephalosporins; Drug Hypersensitivity; Female; Humans | 1991 |
Cimetidine in the treatment of refractory anaphylaxis.
Topics: Anaphylaxis; Cefuroxime; Cimetidine; Drug Hypersensitivity; Female; Flushing; Humans; Hypotension; I | 1989 |