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cefuroxime and Body Weight

cefuroxime has been researched along with Body Weight in 7 studies

Cefuroxime: Broad-spectrum cephalosporin antibiotic resistant to beta-lactamase. It has been proposed for infections with gram-negative and gram-positive organisms, GONORRHEA, and HAEMOPHILUS.
cefuroxime : A 3-(carbamoyloxymethyl)cephalosporin compound having a 7-(2Z)-2-(furan-2-yl)-2-(methoxyimino)acetamido side chain.

Body Weight: The mass or quantity of heaviness of an individual. It is expressed by units of pounds or kilograms.

Research Excerpts

ExcerptRelevanceReference
"The pharmacokinetics of cefuroxime was affected by malnutrition, suggesting that the absorption process via the transporter was modified in the malnourished groups, specially in the group fed with a low quality protein."7.74Effect of malnutrition on the pharmacokinetics of cefuroxime axetil in young rats. ( González-Hernández, I; Jung-Cook, H; Sotelo, A, 2008)
"Most pharmacokinetic studies of antibodies in pregnancy have been carried out at the time of abortion or delivery."5.26Pharmacokinetics of cefuroxime in pregnancy. ( Philipson, A; Stiernstedt, G, 1982)
"The pharmacokinetics of cefuroxime was affected by malnutrition, suggesting that the absorption process via the transporter was modified in the malnourished groups, specially in the group fed with a low quality protein."3.74Effect of malnutrition on the pharmacokinetics of cefuroxime axetil in young rats. ( González-Hernández, I; Jung-Cook, H; Sotelo, A, 2008)
"Preterm and term newborn infants show wide interindividual variability (IIV) in pharmacokinetic parameters of gentamicin."2.74Developmental pharmacokinetics of gentamicin in preterm and term neonates: population modelling of a prospective study. ( Ewald, U; Friberg, LE; Honoré, PH; Nielsen, EI; Sandström, M, 2009)
"Cefuroxime was administered intravenously as a bolus according to weight (20 mg/kg)."1.72Weight-based cefuroxime dosing provides comparable orthopedic target tissue concentrations between weight groups - a microdialysis porcine study. ( Bue, M; Falstie-Jensen, T; Hanberg, P; Knudsen, MB; Schmedes, AV; Stilling, M; Thillemann, TM; Tøstesen, SK; Tøttrup, M, 2022)
"BMI ≥ 35 or weight ≥ 100 kg may serve as a cutoff for higher perioperative dosage of antibiotics."1.43Body mass and weight thresholds for increased prosthetic joint infection rates after primary total joint arthroplasty. ( Christofilopoulos, P; Harbarth, S; Hoffmeyer, P; Lübbeke, A; Miozzari, HH; Uçkay, I; Vu, D; Zingg, M, 2016)
"Most pharmacokinetic studies of antibodies in pregnancy have been carried out at the time of abortion or delivery."1.26Pharmacokinetics of cefuroxime in pregnancy. ( Philipson, A; Stiernstedt, G, 1982)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19901 (14.29)18.7374
1990's1 (14.29)18.2507
2000's2 (28.57)29.6817
2010's1 (14.29)24.3611
2020's2 (28.57)2.80

Authors

AuthorsStudies
Tøstesen, SK1
Hanberg, P1
Bue, M1
Thillemann, TM1
Falstie-Jensen, T1
Tøttrup, M1
Knudsen, MB1
Schmedes, AV1
Stilling, M1
Sommerstein, R1
Atkinson, A1
Kuster, SP1
Vuichard-Gysin, D1
Harbarth, S2
Troillet, N1
Widmer, AF1
Lübbeke, A1
Zingg, M1
Vu, D1
Miozzari, HH1
Christofilopoulos, P1
Uçkay, I1
Hoffmeyer, P1
Nielsen, EI1
Sandström, M1
Honoré, PH1
Ewald, U1
Friberg, LE1
González-Hernández, I1
Jung-Cook, H1
Sotelo, A1
Philipson, A1
Stiernstedt, G1
Gardiner, KR1
Anderson, NH1
McCaigue, MD1
Erwin, PJ1
Halliday, MI1
Rowlands, BJ1

Trials

1 trial available for cefuroxime and Body Weight

ArticleYear
Developmental pharmacokinetics of gentamicin in preterm and term neonates: population modelling of a prospective study.
    Clinical pharmacokinetics, 2009, Volume: 48, Issue:4

    Topics: Age Factors; Biomarkers; Body Weight; Cefuroxime; Creatinine; Cystatin C; Drug Interactions; Female;

2009

Other Studies

6 other studies available for cefuroxime and Body Weight

ArticleYear
Weight-based cefuroxime dosing provides comparable orthopedic target tissue concentrations between weight groups - a microdialysis porcine study.
    APMIS : acta pathologica, microbiologica, et immunologica Scandinavica, 2022, Volume: 130, Issue:2

    Topics: Animals; Anti-Bacterial Agents; Antibiotic Prophylaxis; Body Weight; Cefuroxime; Drug Administration

2022
Association Between Antimicrobial Prophylaxis With Double-Dose Cefuroxime and Surgical Site Infections in Patients Weighing 80 kg or More.
    JAMA network open, 2021, 12-01, Volume: 4, Issue:12

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Antibiotic Prophylaxis; Body Weig

2021
Body mass and weight thresholds for increased prosthetic joint infection rates after primary total joint arthroplasty.
    Acta orthopaedica, 2016, Volume: 87, Issue:2

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Antibiotic Prophylaxis; Arthropla

2016
Effect of malnutrition on the pharmacokinetics of cefuroxime axetil in young rats.
    Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques, 2008, Volume: 11, Issue:1

    Topics: Age Factors; Animals; Body Weight; Cefuroxime; Dietary Proteins; Intestinal Absorption; Liver; Male;

2008
Pharmacokinetics of cefuroxime in pregnancy.
    American journal of obstetrics and gynecology, 1982, Apr-01, Volume: 142, Issue:7

    Topics: Amniotic Fluid; Body Weight; Cefuroxime; Cephalosporins; Delivery, Obstetric; Female; Fetal Blood; H

1982
Enteral and parenteral anti-endotoxin treatment in experimental colitis.
    Hepato-gastroenterology, 1994, Volume: 41, Issue:6

    Topics: Animals; Anti-Infective Agents, Local; Antitoxins; Body Weight; Cefuroxime; Colitis; Endotoxins; Ent

1994