Page last updated: 2024-10-24

cefuroxime and Blood Poisoning

cefuroxime has been researched along with Blood Poisoning in 36 studies

Cefuroxime: Broad-spectrum cephalosporin antibiotic resistant to beta-lactamase. It has been proposed for infections with gram-negative and gram-positive organisms, GONORRHEA, and HAEMOPHILUS.
cefuroxime : A 3-(carbamoyloxymethyl)cephalosporin compound having a 7-(2Z)-2-(furan-2-yl)-2-(methoxyimino)acetamido side chain.

Research Excerpts

ExcerptRelevanceReference
"FT is more effective than cefuroxime, which is commonly used during the perioperative period of urinary stones, and exerts a high antibacterial effect on these internal bacteria, and effectively reduces the probability of infection and sepsis after urinary stone surgery."5.34Antibacterial effect of fosfomycin tromethamine on the bacteria inside urinary infection stones. ( Hu, Z; Lei, Y; Liu, C; Song, F; Zhang, J, 2020)
"A series of patients aged 3 months to 15 years who fulfilled strict criteria for bacterial pneumonia, other respiratory infections, sepsis-like infections, and other acute infections were prospectively randomized to receive parenteral penicillin or cefuroxime randomly for 4 or 7 days."5.09Successful shortening from seven to four days of parenteral beta-lactam treatment for common childhood infections: a prospective and randomized study. ( Kallio, MJ; Peltola, H; Vuori-Holopainen, E, 2001)
" influenzae type b preseptal cellulitis is reported who initially responded to treatment with intravenous cefuroxime and oral cefaclor."3.67Onset of Hemophilus influenzae type-b meningitis during cefaclor therapy for preseptal cellulitis. ( Barson, WJ; Brady, MT; Cannon, HJ; Grossman, LK, 1987)
"Cefuroxime was chosen as the PBP-3-active antibiotic and tobramycin represented the aminoglycosides."1.56Mode of bacterial killing affects the inflammatory response and associated organ dysfunctions in a porcine E. coli intensive care sepsis model. ( Larsson, A; Lipcsey, M; Maudsdotter, L; Sjölin, J; Skorup, P, 2020)
"A working diagnosis of severe septicemia with acute meningoencephalitis was then made and the patient was started on IV Cephtriaxone (2 g) twice daily."1.46A case report: primary amoebic meningoencephalitis in a young Zambian adult. ( Chomba, M; Fwoloshi, S; Mucheleng'anga, LA; Mutengo, MM; Ngulube, J, 2017)
"All animals developed severe sepsis/septic shock."1.40Beneficial antimicrobial effect of the addition of an aminoglycoside to a β-lactam antibiotic in an E. coli porcine intensive care severe sepsis model. ( Castegren, M; Jonsson, AB; Larsson, A; Lipcsey, M; Maudsdotter, L; Sjölin, J; Skorup, P, 2014)
"Sepsis was higher in neonates with fever and hypothermia (p=0."1.38Neonatal sepsis at Muhimbili National Hospital, Dar es Salaam, Tanzania; aetiology, antimicrobial sensitivity pattern and clinical outcome. ( Fredrick, F; Massawe, A; Matee, MI; Mhada, TV, 2012)
" The pharmacokinetic profile of cefuroxime exhibited both one and two compartmental distribution."1.35Effect of severity disease on the pharmacokinetics of cefuroxime in children with multiple organ system failure. ( Asseff, IL; Guillé, GP; Olguín, HJ; Pérez, AG; Quesada, AC; Saldaña, NG; Vieyra, AC, 2008)
"All the babies had septic arthritis and ten cases had osteomyelitis in addition: multiple joint involvement occurred in 50% of cases."1.29Klebsiella septicaemia, osteomyelitis and septic arthritis in neonates in Ibadan, Nigeria. ( Adeyemo, AA; Akindele, JA; Omokhodion, SI, 1993)
"Treatment with cefuroxime appears to be a safe and effective therapy for pediatric soft-tissue infections due to H influenzae and S pneumoniae."1.27Cefuroxime therapy for bacteremic soft-tissue infections in children. ( Barson, WJ; Brady, MT; Hribar, MM; Marcon, MJ; Miller, MA; Pacini, DL; Powell, DA, 1985)
"Cefuroxime was active against all the gram-positive bacteria isolated from our patients as well as most of the gram-negatives."1.26Cefuroxime in soft tissue infections and septicaemia. ( Dornbusch, K; Hugo, H; Sterner, G, 1980)
"pneumoniae was inhibited in concentration of less than 3."1.26[Laboratory and clinical studies on cefuroxime (author's transl)]. ( Hiromatsu, K; Kotani, Y; Nishimura, T; Tabuki, K; Takashima, T, 1979)

Research

Studies (36)

TimeframeStudies, this research(%)All Research%
pre-199014 (38.89)18.7374
1990's6 (16.67)18.2507
2000's6 (16.67)29.6817
2010's6 (16.67)24.3611
2020's4 (11.11)2.80

Authors

AuthorsStudies
Jacewicz, M1
Günzel, K1
Rud, E1
Sandbæk, G1
Magheli, A1
Busch, J1
Hinz, S1
Baco, E1
Owusu, M1
Acheampong, G1
Annan, A1
Marfo, KS1
Osei, I1
Amuasi, J1
Sarpong, N1
Im, J1
Mogeni, OD1
Chiang, HY1
Kuo, CH1
Jeon, HJ1
Panzner, U1
Park, SE1
Marks, F1
Owusu-Dabo, E1
Adu-Sarkodie, Y1
Song, F1
Liu, C1
Zhang, J1
Lei, Y1
Hu, Z1
Skorup, P3
Maudsdotter, L3
Lipcsey, M3
Larsson, A3
Sjölin, J3
de Vries Schultink, AHM1
Sallevelt, BTGM1
Meinders, AJ1
van de Garde, EMW1
Roescher, N1
Chomba, M1
Mucheleng'anga, LA1
Fwoloshi, S1
Ngulube, J1
Mutengo, MM1
Bauer, M1
Krüger, R1
Kölsch, U1
Unterwalder, N1
Meisel, C1
Wahn, V1
von Bernuth, H1
Tano, E1
Castegren, M2
Jonsson, AB1
Mhada, TV1
Fredrick, F1
Matee, MI1
Massawe, A1
Holak, H1
Becker, R1
Holak, S1
Bauhofer, A1
Celik, I1
Plaul, U1
Wulf, H1
Torossian, A1
Olguín, HJ1
Asseff, IL1
Vieyra, AC1
Pérez, AG1
Saldaña, NG1
Quesada, AC1
Guillé, GP1
Geroulanos, S1
Donfried, B1
Turina, M1
Mitchell-Jones, PJ1
Sankey, RJ1
Seufert, RM1
Germann, G1
Böttcher, W1
Jafusco, F1
Ansanelli, V1
Di Lena, C1
Marget, W1
Belohradsky, BH1
Roos, R1
Hugo, H1
Dornbusch, K2
Sterner, G1
Adeyemo, AA1
Akindele, JA1
Omokhodion, SI1
Galloway, A1
Glesson, HK1
Thomas, LR1
Baden, L1
Zaleznik, DF1
Peltola, H1
Vuori-Holopainen, E1
Kallio, MJ1
Pérez-Trallero, E1
Alkorta, M1
Giménez, MJ1
Vicente, D1
Aguilar, L1
Maw, A1
Eu, KW1
Seow-Choen, F1
Nishimura, T1
Hiromatsu, K1
Takashima, T1
Tabuki, K1
Kotani, Y1
Dofferhoff, AS1
Bom, VJ1
van Ingen, J1
de Vries-Hospers, HG1
Hazenberg, BP1
van der Meer, J1
Mulder, PO1
Weits, J1
Wu, SW1
Göransson, E1
Ransjö, U1
Kronvall, G1
Gothefors, L1
Choo, PW1
Gantz, NM1
Huovinen, S1
Huovinen, P1
Torniainen, K1
Jacoby, GA1
Rödjer, S1
Alestig, K1
Bergmark, J1
Bergström, T1
Hultberg, B1
Jagenburg, R1
Olaisson, L1
Trollfors, B1
Westin, J1
Morran, C1
Greig, J1
Gunn, R1
Mason, B1
Sleigh, D1
Haddock, G1
McArdle, C1
Brady, MT2
Barson, WJ2
Cannon, HJ1
Grossman, LK1
Frimodt-Møller, N1
Thomsen, VF1
Miller, MA1
Marcon, MJ1
Hribar, MM1
Pacini, DL1
Powell, DA1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Prospective Randomized Trial of Antibiotic Prophylaxis Versus None Before Transperineal MRI-TRUS Fusion Guided Prostate Biopsy[NCT04146142]550 participants (Actual)Interventional2019-11-11Completed
Tolerance and Efficacy of Amiklin Administration During Nosocomial Infections Complicating COVID-19 in the ICU[NCT05511129]1,053 participants (Actual)Observational2022-05-12Active, not recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

7 trials available for cefuroxime and Blood Poisoning

ArticleYear
Antibiotic prophylaxis versus no antibiotic prophylaxis in transperineal prostate biopsies (NORAPP): a randomised, open-label, non-inferiority trial.
    The Lancet. Infectious diseases, 2022, Volume: 22, Issue:10

    Topics: Anti-Bacterial Agents; Biopsy; Cefuroxime; Humans; Male; Prostate; Sepsis; Urinary Tract Infections

2022
Antibacterial effect of fosfomycin tromethamine on the bacteria inside urinary infection stones.
    International urology and nephrology, 2020, Volume: 52, Issue:4

    Topics: Adult; Aged; Anti-Bacterial Agents; Antibiotic Prophylaxis; Bacteria; Cefuroxime; Colony Count, Micr

2020
Plasma levels of ceftriaxone in cardiovascular surgery.
    American journal of surgery, 1984, Oct-19, Volume: 148, Issue:4A

    Topics: Bacterial Infections; Cardiac Surgical Procedures; Cefotaxime; Ceftriaxone; Cefuroxime; Clinical Tri

1984
[Perioperative antibiotic prophylaxis in elective splenectomy. A randomized prospective study].
    Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen, 1984, Volume: 55, Issue:6

    Topics: Adult; Cefuroxime; Cephalosporins; Humans; Male; Middle Aged; Pneumonia; Postoperative Complications

1984
Successful shortening from seven to four days of parenteral beta-lactam treatment for common childhood infections: a prospective and randomized study.
    International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases, 2001, Volume: 5, Issue:1

    Topics: Adolescent; Bacterial Infections; Cefuroxime; Child; Child, Preschool; Female; Humans; Infant; Male;

2001
Treatment of septicaemia in immunocompromised patients with ceftazidime or with tobramycin and cefuroxime, with special reference to renal effects.
    The Journal of antimicrobial chemotherapy, 1987, Volume: 20, Issue:1

    Topics: Adult; Aged; Ceftazidime; Cefuroxime; Female; Humans; Immunologic Deficiency Syndromes; Kidney; Kidn

1987
A comparison of cefuroxime and cefotetan in the prevention of wound sepsis after gastrointestinal surgery.
    Chemioterapia : international journal of the Mediterranean Society of Chemotherapy, 1987, Volume: 6, Issue:2 Suppl

    Topics: Bacteria; Cefotetan; Cefuroxime; Cephalosporins; Clinical Trials as Topic; Gastrointestinal Diseases

1987

Other Studies

29 other studies available for cefuroxime and Blood Poisoning

ArticleYear
Ralstonia mannitolilytica sepsis: a case report.
    Journal of medical case reports, 2019, Oct-26, Volume: 13, Issue:1

    Topics: Anti-Bacterial Agents; Cefuroxime; Child, Preschool; Female; Ghana; Gram-Negative Bacterial Infectio

2019
Mode of bacterial killing affects the inflammatory response and associated organ dysfunctions in a porcine E. coli intensive care sepsis model.
    Critical care (London, England), 2020, 11-14, Volume: 24, Issue:1

    Topics: Animals; Cefuroxime; Disease Models, Animal; Endotoxins; Escherichia coli; Escherichia coli Infectio

2020
The need for gentamicin adjunctive to cefuroxime as empirical sepsis therapy: a local protocol evaluation.
    Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases, 2021, Volume: 27, Issue:9

    Topics: Anti-Bacterial Agents; Cefuroxime; Cephalosporins; Gentamicins; Humans; Sepsis

2021
A case report: primary amoebic meningoencephalitis in a young Zambian adult.
    BMC infectious diseases, 2017, 08-01, Volume: 17, Issue:1

    Topics: Amphotericin B; Animals; Anti-Bacterial Agents; Cefuroxime; Central Nervous System Protozoal Infecti

2017
Antibiotic Prophylaxis, Immunoglobulin Substitution and Supportive Measures Prevent Infections in MECP2 Duplication Syndrome.
    The Pediatric infectious disease journal, 2018, Volume: 37, Issue:5

    Topics: Administration, Intravenous; Anti-Bacterial Agents; Antibiotic Prophylaxis; Cefuroxime; Humans; IgA

2018
Dynamics of Endotoxin, Inflammatory Variables, and Organ Dysfunction After Treatment With Antibiotics in an Escherichia coli Porcine Intensive Care Sepsis Model.
    Critical care medicine, 2018, Volume: 46, Issue:7

    Topics: Animals; Anti-Bacterial Agents; Cefuroxime; Disease Models, Animal; Drug Therapy, Combination; Endot

2018
Beneficial antimicrobial effect of the addition of an aminoglycoside to a β-lactam antibiotic in an E. coli porcine intensive care severe sepsis model.
    PloS one, 2014, Volume: 9, Issue:2

    Topics: Animals; Anti-Bacterial Agents; Bacteremia; Bacterial Load; Cefuroxime; Critical Care; Disease Model

2014
Neonatal sepsis at Muhimbili National Hospital, Dar es Salaam, Tanzania; aetiology, antimicrobial sensitivity pattern and clinical outcome.
    BMC public health, 2012, Oct-24, Volume: 12

    Topics: Amikacin; Ampicillin; Anti-Infective Agents; Ceftriaxone; Cefuroxime; Cloxacillin; Escherichia coli;

2012
[Long-term follow-up of bilateral endogenous Klebsiella endophthalmitis].
    Klinische Monatsblatter fur Augenheilkunde, 2003, Volume: 220, Issue:5

    Topics: Abscess; Aged; Cefotaxime; Cefuroxime; Drug Therapy, Combination; Endophthalmitis; Follow-Up Studies

2003
Effects of G-CSF and antibiotic prophylaxis in a 2 x 2 factorial design on outcome in septic rats.
    Inflammation research : official journal of the European Histamine Research Society ... [et al.], 2004, Volume: 53 Suppl 2

    Topics: Abdomen; Animals; Antibiotic Prophylaxis; Cefuroxime; Clinical Trials as Topic; Disease Models, Anim

2004
Effect of severity disease on the pharmacokinetics of cefuroxime in children with multiple organ system failure.
    Biological & pharmaceutical bulletin, 2008, Volume: 31, Issue:2

    Topics: Adolescent; Alanine Transaminase; Algorithms; Area Under Curve; Aspartate Aminotransferases; Cefurox

2008
A case of recurrent salmonella septicaemia in an infant.
    Postgraduate medical journal, 1984, Volume: 60, Issue:706

    Topics: Cefuroxime; Cephalosporins; Chloramphenicol; Drug Combinations; Female; Humans; IgA Deficiency; Infa

1984
[Experience with the therapeutic use of cefuroxime in neonatology].
    La Pediatria, 1981, Mar-31, Volume: 89, Issue:1

    Topics: Bacterial Infections; Cefuroxime; Cephalosporins; Gastroenteritis; Humans; Infant, Newborn; Infant,

1981
Guidelines for adequate chemotherapeutic dosage in newborns and infants with septicaemia and meningitis.
    Infection, 1980, Volume: Suppl 1

    Topics: Amikacin; Anti-Bacterial Agents; Cefuroxime; Colistin; Dose-Response Relationship, Drug; Humans; Inf

1980
Cefuroxime in soft tissue infections and septicaemia.
    Scandinavian journal of infectious diseases, 1980, Volume: 12, Issue:3

    Topics: Adolescent; Adult; Aged; Bacterial Infections; Cefuroxime; Cephalosporins; Drug Tolerance; Female; H

1980
Klebsiella septicaemia, osteomyelitis and septic arthritis in neonates in Ibadan, Nigeria.
    Annals of tropical paediatrics, 1993, Volume: 13, Issue:3

    Topics: Arthritis, Infectious; Ceftazidime; Cefuroxime; Cloxacillin; Cross Infection; Cross-Sectional Studie

1993
Survival following group A streptococcal septicaemia in a centenarian.
    The Journal of infection, 1999, Volume: 38, Issue:3

    Topics: Administration, Oral; Aged; Aged, 80 and over; Amoxicillin; Cefuroxime; Cephalosporins; Female; Huma

1999
Clinical problem-solving. Chest pain with a surprising course.
    The New England journal of medicine, 1999, Oct-07, Volume: 341, Issue:15

    Topics: Aged; Anuria; Cefuroxime; Cephalosporins; Chest Pain; Cholecystitis; Clostridium Infections; Clostri

1999
Prediction of in-vivo efficacy by in-vitro early bactericidal activity with oral beta-lactams, in a dose-ranging immunocompetent mouse sepsis model, using strains of Streptococcus pneumoniae with decreasing susceptibilities to penicillin.
    Journal of chemotherapy (Florence, Italy), 2001, Volume: 13, Issue:2

    Topics: Amoxicillin; Animals; Area Under Curve; Cefpodoxime; Ceftizoxime; Cefuroxime; Cephalosporins; Diseas

2001
Retroperitoneal sepsis complicating stapled hemorrhoidectomy: report of a case and review of the literature.
    Diseases of the colon and rectum, 2002, Volume: 45, Issue:6

    Topics: Adult; Anti-Infective Agents; Cefuroxime; Cephalosporins; Hemorrhoids; Humans; Male; Metronidazole;

2002
[Laboratory and clinical studies on cefuroxime (author's transl)].
    The Japanese journal of antibiotics, 1979, Volume: 32, Issue:12

    Topics: Adolescent; Bacterial Infections; Cefuroxime; Cephalosporins; Child; Child, Preschool; Common Bile D

1979
Patterns of cytokines, plasma endotoxin, and acute phase proteins during the treatment of severe sepsis in humans.
    Progress in clinical and biological research, 1991, Volume: 367

    Topics: Acute-Phase Proteins; Cefuroxime; Cilastatin; Drug Therapy, Combination; Endotoxins; Female; Humans;

1991
Characterization of Klebsiella oxytoca septicaemia isolates resistant to aztreonam and cefuroxime.
    The Journal of antimicrobial chemotherapy, 1991, Volume: 28, Issue:3

    Topics: Aztreonam; beta-Lactamases; Cefuroxime; DNA, Bacterial; Drug Resistance, Microbial; Humans; Klebsiel

1991
[Cefuroxime has a good effect in severe infections in children].
    Lakartidningen, 1990, Sep-12, Volume: 87, Issue:37

    Topics: Aminoglycosides; Anti-Bacterial Agents; Cefuroxime; Child, Preschool; Humans; Infant; Infant, Newbor

1990
Branhamella catarrhalis pneumonia with bacteremia.
    Southern medical journal, 1989, Volume: 82, Issue:10

    Topics: Aged; Ceftriaxone; Cefuroxime; Cross Infection; Female; Humans; Moraxella catarrhalis; Pneumonia; Se

1989
Evaluation of plasmid-encoded beta-lactamase resistance in Escherichia coli blood culture isolates.
    European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 1988, Volume: 7, Issue:5

    Topics: Ampicillin; Anti-Bacterial Agents; beta-Lactamases; Cefuroxime; Drug Resistance, Microbial; Enteroba

1988
Onset of Hemophilus influenzae type-b meningitis during cefaclor therapy for preseptal cellulitis.
    Clinical pediatrics, 1987, Volume: 26, Issue:3

    Topics: Cefaclor; Ceftriaxone; Cefuroxime; Cellulitis; Cephalexin; Drug Resistance, Microbial; Haemophilus I

1987
The pneumococcus and the mouse protection test: inoculum, dosage and timing.
    Acta pathologica, microbiologica, et immunologica Scandinavica. Section B, Microbiology, 1986, Volume: 94, Issue:1

    Topics: Animals; Anti-Bacterial Agents; Cefotaxime; Cefuroxime; Dose-Response Relationship, Drug; Female; In

1986
Cefuroxime therapy for bacteremic soft-tissue infections in children.
    American journal of diseases of children (1960), 1985, Volume: 139, Issue:11

    Topics: beta-Lactamases; Cefuroxime; Cellulitis; Cephalosporins; Child, Preschool; Drug Resistance, Microbia

1985