Page last updated: 2024-10-24

cefuroxime and Bacteremia

cefuroxime has been researched along with Bacteremia in 34 studies

Cefuroxime: Broad-spectrum cephalosporin antibiotic resistant to beta-lactamase. It has been proposed for infections with gram-negative and gram-positive organisms, GONORRHEA, and HAEMOPHILUS.
cefuroxime : A 3-(carbamoyloxymethyl)cephalosporin compound having a 7-(2Z)-2-(furan-2-yl)-2-(methoxyimino)acetamido side chain.

Bacteremia: The presence of viable bacteria circulating in the blood. Fever, chills, tachycardia, and tachypnea are common acute manifestations of bacteremia. The majority of cases are seen in already hospitalized patients, most of whom have underlying diseases or procedures which render their bloodstreams susceptible to invasion.

Research Excerpts

ExcerptRelevanceReference
"Our objective was to examine whether empirical antimicrobial therapy (EAT) against methicillin-susceptible Staphylococcus aureus bacteremia (MS-SAB) with piperacillin-tazobactam (TZP), cefuroxime or combination therapy with one of these was differentially associated with 7-, 30-, and 90- day all-cause mortality or MS-SAB relapse."8.12Comparable Effectiveness of Cefuroxime and Piperacillin-Tazobactam as Empirical Therapy for Methicillin-Susceptible Staphylococcus aureus Bacteremia. ( Benfield, T; Bigseth, RS; Petersen, A; Sandholdt, H; Thorlacius-Ussing, L; Østergaard, C, 2022)
"Our objective was to examine whether empirical antimicrobial therapy (EAT) against methicillin-susceptible Staphylococcus aureus bacteremia (MS-SAB) with piperacillin-tazobactam (TZP), cefuroxime or combination therapy with one of these was differentially associated with 7-, 30-, and 90- day all-cause mortality or MS-SAB relapse."4.12Comparable Effectiveness of Cefuroxime and Piperacillin-Tazobactam as Empirical Therapy for Methicillin-Susceptible Staphylococcus aureus Bacteremia. ( Benfield, T; Bigseth, RS; Petersen, A; Sandholdt, H; Thorlacius-Ussing, L; Østergaard, C, 2022)
"Our results suggest that, after susceptibility testing, cefuroxime or aminopenicillins are preferable to benzylpenicillins as definitive therapy for Haemophilus bacteremia."3.78Treatment of Haemophilus bacteremia with benzylpenicillin is associated with increased (30-day) mortality. ( Thønnings, S; Østergaard, C, 2012)
" We report a toddler who had breakthrough bacteremia and meningitis develop because of drug-resistant pneumococcus while receiving treatment with cefotaxime and cefuroxime for pneumonia."3.70Breakthrough bacteremia and meningitis during treatment with cephalosporins parenterally for pneumococcal pneumonia. ( Brown, SP; Buckingham, SC; Joaquin, VH, 1998)
"In addition, septic shock occurred in 6 cases (2."2.73Incidence of postoperative infections in patients undergoing coronary artery bypass grafting surgery receiving antimicrobial prophylaxis with original and generic cefuroxime. ( Falagas, M; Falagas, ME; Geroulanos, S; Karatza, D; Kriaras, I; Mastoraki, E; Michalopoulos, A; Mouchtouri, E, 2008)
"Also for lower respiratory tract infections (LTRI) the clinical and bacteriological responses were quite similar, although relatively more failures occurred in CF treated patients with LRTI caused by pneumococci."2.67Ciprofloxacin versus a tobramycin/cefuroxime combination in the treatment of serious systemic infections: a prospective, randomized and controlled study of efficacy and safety. ( Andersen, BM; Bergan, T; Brubakk, O; Bruun, JN; Døskeland, B; Hellum, KB; Hopen, G; Kalager, T; Rahm, V; von der Lippe, E, 1992)
"Standard once-daily dosing of ceftriaxone may not lead to adequate antibiotic exposure in all cases of Staphylococcus aureus bacteraemia (SAB)."1.91Comparative effectiveness of β-lactams for empirical treatment of methicillin-susceptible Staphylococcus aureus bacteraemia: a prospective cohort study. ( Bonten, MJM; Buis, DTP; Herpers, BL; Jansen, RR; Prins, JM; Rozemeijer, W; Sieswerda, E; Sigaloff, KCE; Soetekouw, R; van der Meer, JTM; van der Vaart, TW; van Twillert, G; van Werkhoven, CH; Veenstra, J, 2023)
"Cefuroxime was the initial empiric antimicrobial agent given for 66/76 of the patients and treatment outcome was favorable for 20/22 patients who received cefuroxime at least up to day 5."1.72Clinical and microbiological characterization of Aerococcus urinae bacteraemias at Helsinki metropolitan area, Finland. ( Grönroos, JO; Lehtola, L; Pakarinen, L; Pätäri-Sampo, A; Rantakokko-Jalava, K; Sihvonen, R; Turunen, M, 2022)
"G."1.48Bacteramia Caused by Gardnerella Vaginalis in a Cesarean Section Patient. ( Chen, Y; Guo, P; Han, X; Huang, H; Liao, K; Wu, Z, 2018)
"All animals developed severe sepsis/septic shock."1.40Beneficial antimicrobial effect of the addition of an aminoglycoside to a β-lactam antibiotic in an E. coli porcine intensive care severe sepsis model. ( Castegren, M; Jonsson, AB; Larsson, A; Lipcsey, M; Maudsdotter, L; Sjölin, J; Skorup, P, 2014)
"Despite the clinical significance of Salmonella infections, surveillance data worldwide remains limited and is more so exemplified by the lack of reports from Africa especially in eastern, central and western Africa."1.40Salmonella blood stream infections in a tertiary care setting in Ghana. ( Addison, NO; Donkor, ES; Labi, AK; Obeng-Nkrumah, N, 2014)
"Paraspinal abscess and spondylodiscitis due to Citrobacter koseri is a very rare condition."1.38Citrobacter koseri bacteraemia complicated by paraspinal abscess and spondylodiscitis--a case report. ( Hayati, SN; Kumar, CS; Lee, C; Leong, CL, 2012)
"Infants and children with pneumococcal infections cared for at eight children's hospitals."1.31Outcome of invasive infections outside the central nervous system caused by Streptococcus pneumoniae isolates nonsusceptible to ceftriazone in children treated with beta-lactam antibiotics. ( Barson, WJ; Bradley, JS; Givner, LB; Kaplan, SL; Kim, KS; Mason, EO; Schutze, GE; Tan, TQ; Wald, ER; Yogev, R, 2001)

Research

Studies (34)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's14 (41.18)18.2507
2000's6 (17.65)29.6817
2010's11 (32.35)24.3611
2020's3 (8.82)2.80

Authors

AuthorsStudies
Sihvonen, R1
Turunen, M1
Lehtola, L1
Pakarinen, L1
Grönroos, JO1
Rantakokko-Jalava, K1
Pätäri-Sampo, A1
Bigseth, RS1
Sandholdt, H1
Petersen, A1
Østergaard, C2
Benfield, T3
Thorlacius-Ussing, L1
Buis, DTP1
van der Vaart, TW1
Prins, JM1
van der Meer, JTM1
Bonten, MJM1
Sieswerda, E1
van Werkhoven, CH1
Sigaloff, KCE1
Herpers, BL1
Jansen, RR1
Rozemeijer, W1
Soetekouw, R1
van Twillert, G1
Veenstra, J1
Chen, Y1
Han, X1
Guo, P1
Huang, H1
Wu, Z1
Liao, K1
Nissen, JL1
Skov, R1
Knudsen, JD2
Ostergaard, C2
Schønheyder, HC2
Frimodt-Møller, N1
Crane, JK1
Rasmussen, JB1
Arpi, M1
van der Vusse, ML1
van Son, WJ1
Ott, A1
Manson, W1
Skorup, P1
Maudsdotter, L1
Lipcsey, M1
Castegren, M1
Larsson, A1
Jonsson, AB1
Sjölin, J1
Labi, AK1
Obeng-Nkrumah, N1
Addison, NO1
Donkor, ES2
Bremmer, DN1
Balada-Llasat, JM1
Goff, DA1
Bauer, KA1
Melendez, J1
Claxton, A1
Erskine, K1
Thønnings, S1
Hayati, SN1
Leong, CL1
Kumar, CS1
Lee, C1
Otermin, I1
Lai, CH1
Hwang, CK1
Chin, C1
Lin, HH1
Wong, WW1
Liu, CY1
Kariuki, S1
Revathi, G1
Kariuki, N1
Kiiru, J1
Mwituria, J1
Hart, CA1
Mastoraki, E1
Michalopoulos, A1
Kriaras, I1
Mouchtouri, E1
Falagas, ME1
Falagas, M1
Karatza, D1
Geroulanos, S1
Amyes, SG1
Baird, DR1
Crook, DW1
Gillespie, SH1
Howard, AJ1
Oppenhiem, BA1
Pedler, SJ1
Paull, A1
Tompkins, DS1
Lawrie, SA1
Arstila, T1
Auvinen, H1
Huovinen, P1
Patrick, CC1
Furuta, GT1
Edwards, M1
Estabrook, M1
Blake, MS1
Baker, CJ1
Krause, I1
Nimri, R1
Domínguez, H1
Vogel, BF1
Gram, L1
Hoffmann, S1
Schaebel, S1
Nohara, T1
Kobayashi, I1
Mathur, YC1
Mathur, NC1
Lal, HM1
Levi, N1
Eiberg, J1
Skov Jensen, J1
Prag, J1
Jørgensen, J1
Schroeder, TV1
Buckingham, SC1
Brown, SP1
Joaquin, VH1
Wahlmann, U1
Al-Nawas, B1
Jütte, M1
Wagner, W1
Arnez, M1
Ruzić-Sabljić, E1
Ahcan, J1
Radsel-Medvescek, A1
Pleterski-Rigler, D1
Strle, F1
Kaplan, SL1
Mason, EO1
Barson, WJ1
Tan, TQ1
Schutze, GE1
Bradley, JS1
Givner, LB1
Kim, KS1
Yogev, R1
Wald, ER1
Katoh, H1
Singh, KP1
Voolmann, T1
Lang, SD1
Kalager, T1
Andersen, BM1
Bergan, T1
Brubakk, O1
Bruun, JN1
Døskeland, B1
Hellum, KB1
Hopen, G1
von der Lippe, E1
Rahm, V1
Biermann, H1
Rick, C1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Pilot Randomised Controlled Trial of Penicillin Versus Flucloxacillin for Definitive Treatment of Invasive Penicillin Susceptible Staphylococcus Aureus[NCT03632642]Phase 40 participants (Actual)Interventional2019-07-01Withdrawn (stopped due to Study never commenced)
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

4 trials available for cefuroxime and Bacteremia

ArticleYear
Incidence of postoperative infections in patients undergoing coronary artery bypass grafting surgery receiving antimicrobial prophylaxis with original and generic cefuroxime.
    The Journal of infection, 2008, Volume: 56, Issue:1

    Topics: Anti-Bacterial Agents; Antibiotic Prophylaxis; Bacteremia; Cefuroxime; Coronary Artery Bypass; Drug

2008
Clinical and microbiological efficacy of single dose cefuroxime prophylaxis for dental surgical procedures.
    International journal of antimicrobial agents, 1999, Volume: 12, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Bacteremia; Cefuroxime; Dentistry, Operative; Drug Administration Sc

1999
Incidence of transient bacteremia following dental surgery--prophylactic use of cefuroxime, ceftriaxone or clindamycin.
    The Tokai journal of experimental and clinical medicine, 1992, Volume: 17, Issue:3-4

    Topics: Adult; Aged; Anti-Bacterial Agents; Bacteremia; Ceftriaxone; Cefuroxime; Clindamycin; Dentistry, Ope

1992
Ciprofloxacin versus a tobramycin/cefuroxime combination in the treatment of serious systemic infections: a prospective, randomized and controlled study of efficacy and safety.
    Scandinavian journal of infectious diseases, 1992, Volume: 24, Issue:5

    Topics: Adult; Aged; Bacteremia; Cefuroxime; Ciprofloxacin; Drug Therapy, Combination; Female; Humans; Male;

1992

Other Studies

30 other studies available for cefuroxime and Bacteremia

ArticleYear
Clinical and microbiological characterization of Aerococcus urinae bacteraemias at Helsinki metropolitan area, Finland.
    European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 2022, Volume: 41, Issue:5

    Topics: Aerococcus; Aged; Anti-Bacterial Agents; Bacteremia; Ceftriaxone; Cefuroxime; Disease Susceptibility

2022
Comparable Effectiveness of Cefuroxime and Piperacillin-Tazobactam as Empirical Therapy for Methicillin-Susceptible Staphylococcus aureus Bacteremia.
    Microbiology spectrum, 2022, 06-29, Volume: 10, Issue:3

    Topics: Adult; Anti-Bacterial Agents; Bacteremia; Cefuroxime; Cohort Studies; Humans; Methicillin; Piperacil

2022
Comparative effectiveness of β-lactams for empirical treatment of methicillin-susceptible Staphylococcus aureus bacteraemia: a prospective cohort study.
    The Journal of antimicrobial chemotherapy, 2023, 05-03, Volume: 78, Issue:5

    Topics: Adult; Anti-Bacterial Agents; Bacteremia; beta-Lactams; Ceftriaxone; Cefuroxime; Floxacillin; Humans

2023
Bacteramia Caused by Gardnerella Vaginalis in a Cesarean Section Patient.
    Clinical laboratory, 2018, Mar-01, Volume: 64, Issue:3

    Topics: Adult; Anti-Bacterial Agents; Bacteremia; Cefuroxime; Cesarean Section; Female; Gardnerella vaginali

2018
Effectiveness of penicillin, dicloxacillin and cefuroxime for penicillin-susceptible Staphylococcus aureus bacteraemia: a retrospective, propensity-score-adjusted case-control and cohort analysis.
    The Journal of antimicrobial chemotherapy, 2013, Volume: 68, Issue:8

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Bacteremia; Case-Control Studies;

2013
Resurgence of penicillin-susceptible Staphylococcus aureus at a hospital in New York State, USA.
    The Journal of antimicrobial chemotherapy, 2014, Volume: 69, Issue:1

    Topics: Anti-Bacterial Agents; Bacteremia; Cefuroxime; Dicloxacillin; Female; Humans; Male; Penicillins; Sta

2014
Relative efficacy of cefuroxime versus dicloxacillin as definitive antimicrobial therapy in methicillin-susceptible Staphylococcus aureus bacteraemia: a propensity-score adjusted retrospective cohort study.
    The Journal of antimicrobial chemotherapy, 2014, Volume: 69, Issue:2

    Topics: Aged; Aged, 80 and over; Anti-Bacterial Agents; Bacteremia; Cefuroxime; Cohort Studies; Dicloxacilli

2014
Helicobacter canis bacteremia in a renal transplant patient.
    Transplant infectious disease : an official journal of the Transplantation Society, 2014, Volume: 16, Issue:1

    Topics: Adult; Anti-Bacterial Agents; Bacteremia; Cefuroxime; Ciprofloxacin; DNA, Bacterial; DNA, Ribosomal;

2014
Beneficial antimicrobial effect of the addition of an aminoglycoside to a β-lactam antibiotic in an E. coli porcine intensive care severe sepsis model.
    PloS one, 2014, Volume: 9, Issue:2

    Topics: Animals; Anti-Bacterial Agents; Bacteremia; Bacterial Load; Cefuroxime; Critical Care; Disease Model

2014
Salmonella blood stream infections in a tertiary care setting in Ghana.
    BMC infectious diseases, 2014, Dec-21, Volume: 14

    Topics: Adolescent; Adult; Aged; Anti-Bacterial Agents; Bacteremia; Cefuroxime; Child; Child, Preschool; Dis

2014
Ceftriaxone Etest non-susceptible methicillin susceptible Staphylococcus aureus time-kill responses.
    Diagnostic microbiology and infectious disease, 2017, Volume: 88, Issue:2

    Topics: Anti-Bacterial Agents; Bacteremia; Cefepime; Ceftaroline; Ceftriaxone; Cefuroxime; Cephalosporins; C

2017
MRSA bacteraemia after caesarean section wound infection: when screening is missed and things go wrong.
    Archives of gynecology and obstetrics, 2012, Volume: 285, Issue:3

    Topics: Adult; Amikacin; Anti-Bacterial Agents; Antibiotic Prophylaxis; Bacteremia; Cefuroxime; Cesarean Sec

2012
Treatment of Haemophilus bacteremia with benzylpenicillin is associated with increased (30-day) mortality.
    BMC infectious diseases, 2012, Jul-09, Volume: 12

    Topics: Aged; Anti-Bacterial Agents; Bacteremia; Cefuroxime; Child; Denmark; Disk Diffusion Antimicrobial Te

2012
Citrobacter koseri bacteraemia complicated by paraspinal abscess and spondylodiscitis--a case report.
    The Medical journal of Malaysia, 2012, Volume: 67, Issue:3

    Topics: Abscess; Aged; Anti-Bacterial Agents; Bacteremia; Cefuroxime; Citrobacter koseri; Discitis; Enteroba

2012
[SEIMC protocol on osteoarticular and soft tissue infection, and asymptomatic bacteriuria: value of extended prophylaxis].
    Enfermedades infecciosas y microbiologia clinica, 2003, Volume: 21, Issue:1

    Topics: Anti-Bacterial Agents; Antibiotic Prophylaxis; Bacteremia; Bacteriuria; Bone Diseases, Infectious; C

2003
Severe watery diarrhoea and bacteraemia caused by Vibrio fluvialis.
    The Journal of infection, 2006, Volume: 52, Issue:3

    Topics: Aged; Anti-Bacterial Agents; Bacteremia; Cefuroxime; Diarrhea; Drug Resistance, Multiple, Bacterial;

2006
Characterisation of community acquired non-typhoidal Salmonella from bacteraemia and diarrhoeal infections in children admitted to hospital in Nairobi, Kenya.
    BMC microbiology, 2006, Dec-15, Volume: 6

    Topics: Bacteremia; Ceftriaxone; Cefuroxime; Child; Child, Preschool; Community-Acquired Infections; Diarrhe

2006
A multicentre study of the in-vitro activity of cefotaxime, cefuroxime, ceftazidime, ofloxacin and ciprofloxacin against blood and urinary pathogens.
    The Journal of antimicrobial chemotherapy, 1994, Volume: 34, Issue:5

    Topics: Anti-Infective Agents; Bacteremia; Bacteria; Bacteriuria; Cefotaxime; Ceftazidime; Cefuroxime; Cepha

1994
Beta-lactam resistance among Escherichia coli and Klebsiella species blood culture isolates in Finnish hospitals. Finnish Study Group for Antimicrobial Resistance.
    European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 1994, Volume: 13, Issue:6

    Topics: Bacteremia; beta-Lactam Resistance; Cefuroxime; Cephalosporins; Drug Utilization; Escherichia coli;

1994
Variation in phenotypic expression of the Opa outer membrane protein and lipooligosaccharide of Neisseria meningitidis serogroup C causing periorbital cellulitis and bacteremia.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 1993, Volume: 16, Issue:4

    Topics: Antigens, Bacterial; Bacteremia; Bacterial Outer Membrane Proteins; Cefuroxime; Cellulitis; Electrop

1993
Kingella kingae occult bacteremia in a toddler.
    The Pediatric infectious disease journal, 1996, Volume: 15, Issue:6

    Topics: Age Factors; Bacteremia; Cefuroxime; Cephalosporins; Child, Preschool; Female; Humans; Kingella king

1996
Shewanella alga bacteremia in two patients with lower leg ulcers.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 1996, Volume: 22, Issue:6

    Topics: Aged; Aged, 80 and over; Ampicillin; Anti-Bacterial Agents; Bacteremia; Cefuroxime; Female; Gentamic

1996
Transient bacteremia after tooth extraction with intravenous cefuroxime prophylaxis.
    The Tokai journal of experimental and clinical medicine, 1995, Volume: 20, Issue:4-6

    Topics: Adult; Aged; Bacteremia; Cefuroxime; Cephalosporins; Female; Humans; Injections, Intravenous; Male;

1995
Clinical efficacy of Cefuroxime axetil in S. typhi.
    Indian pediatrics, 1996, Volume: 33, Issue:12

    Topics: Bacteremia; Cefuroxime; Cephalosporins; Child; Female; Follow-Up Studies; Humans; Male; Prodrugs; Re

1996
Mycoplasma in urine and blood following catheterisation of patients undergoing vascular surgery.
    The Journal of cardiovascular surgery, 1997, Volume: 38, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Antibiotic Prophylaxis; Bacteremia; Bacteriuria; Cefuroxime; Cephalo

1997
Breakthrough bacteremia and meningitis during treatment with cephalosporins parenterally for pneumococcal pneumonia.
    The Journal of pediatrics, 1998, Volume: 132, Issue:1

    Topics: Bacteremia; Cefotaxime; Cefuroxime; Cephalosporin Resistance; Cephalosporins; Drug Resistance, Multi

1998
Isolation of Borrelia burgdorferi sensu lato from blood of children with solitary erythema migrans.
    The Pediatric infectious disease journal, 2001, Volume: 20, Issue:3

    Topics: Bacteremia; Bacteriological Techniques; Borrelia burgdorferi Group; Cefuroxime; Cephalosporins; Chil

2001
Outcome of invasive infections outside the central nervous system caused by Streptococcus pneumoniae isolates nonsusceptible to ceftriazone in children treated with beta-lactam antibiotics.
    The Pediatric infectious disease journal, 2001, Volume: 20, Issue:4

    Topics: Anti-Bacterial Agents; Bacteremia; Cefotaxime; Ceftriaxone; Cefuroxime; Cephalosporin Resistance; Ce

2001
Pneumococcal bacteraemia in south Auckland: a five year review with emphasis on prescribing practices.
    The New Zealand medical journal, 1992, Oct-14, Volume: 105, Issue:943

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amoxicillin; Anti-Bacterial Agents; Bacteremia; Cefuroxi

1992
[Comparative studies of preventive antibiotic administration in ERCP].
    Leber, Magen, Darm, 1992, Volume: 22, Issue:3

    Topics: Aged; Aged, 80 and over; Ampulla of Vater; Bacteremia; Cefuroxime; Cholangiopancreatography, Endosco

1992