Page last updated: 2024-10-24

cefuroxime and Appendicitis

cefuroxime has been researched along with Appendicitis in 18 studies

Cefuroxime: Broad-spectrum cephalosporin antibiotic resistant to beta-lactamase. It has been proposed for infections with gram-negative and gram-positive organisms, GONORRHEA, and HAEMOPHILUS.
cefuroxime : A 3-(carbamoyloxymethyl)cephalosporin compound having a 7-(2Z)-2-(furan-2-yl)-2-(methoxyimino)acetamido side chain.

Appendicitis: Acute inflammation of the APPENDIX. Acute appendicitis is classified as simple, gangrenous, or perforated.

Research Excerpts

ExcerptRelevanceReference
"Eighty-four cases of non-perforated appendicitis in children were randomly allocated to receive either oxytetracycline lavage alone or oxytetracycline lavage plus peroperative intravenous metronidazole and cefuroxime."9.06Antibiotic prophylaxis in non-perforated appendicitis of childhood: tetracycline lavage compared with peroperative intravenous cefuroxime and metronidazole. ( Carle, G; Davidson, AI; Miller, SS; Reid, TM; Thomson, SR, 1987)
"A study on 42 surgical patients was carried out to find out whether cefuroxime may be substituted for gentamicin in combination with metronidazole in the treatment of peritonitis secondary to perforation of appendix."9.05Comparison of cefuroxime and gentamicin in combination with metronidazole in the treatment of peritonitis due to perforation of the appendix. ( Arvilommi, H; Saario, I; Silvola, H, 1983)
"A single pre-operative dose of cefuroxime and metronidazole had the same efficacy in preventing surgical site infections in cases of non-perforated appendicitis as when the same regimen was repeated post-operatively."5.20Evaluation of postoperative antibiotics after non-perforated appendectomy. ( Jan, H; Khan, A; Khan, MM; Rafiq, MS, 2015)
"In a randomized controlled trial of 269 patients aged 15-70 years with non-perforated appendicitis undergoing open appendicectomy; 92 received single dose preoperative (group A), 94 received three-dose (group B) and 83 received 5-day perioperative (group C) regimens of cefuroxime and metronidazole."5.11Optimum duration of prophylactic antibiotics in acute non-perforated appendicitis. ( Chung, SS; Fok, KL; Fung, TM; Lam, YH; Mui, LM; Ng, CS; Ng, EK; Wong, SK, 2005)
"Eighty-four cases of non-perforated appendicitis in children were randomly allocated to receive either oxytetracycline lavage alone or oxytetracycline lavage plus peroperative intravenous metronidazole and cefuroxime."5.06Antibiotic prophylaxis in non-perforated appendicitis of childhood: tetracycline lavage compared with peroperative intravenous cefuroxime and metronidazole. ( Carle, G; Davidson, AI; Miller, SS; Reid, TM; Thomson, SR, 1987)
" Patients with free purulent peritonitis due to perforated appendicitis or colonic perforation were treated with intravenous infusion of cefuroxime and metronidazole."5.06A prospective randomized study of continuous peritoneal lavage postoperatively in the treatment of purulent peritonitis. ( Andersson, C; Englund, N; Glise, H; Hallerbäck, B; Nihlberg, A; Solhaug, J; Wahlström, B, 1986)
"A study on 42 surgical patients was carried out to find out whether cefuroxime may be substituted for gentamicin in combination with metronidazole in the treatment of peritonitis secondary to perforation of appendix."5.05Comparison of cefuroxime and gentamicin in combination with metronidazole in the treatment of peritonitis due to perforation of the appendix. ( Arvilommi, H; Saario, I; Silvola, H, 1983)

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19903 (16.67)18.7374
1990's3 (16.67)18.2507
2000's5 (27.78)29.6817
2010's6 (33.33)24.3611
2020's1 (5.56)2.80

Authors

AuthorsStudies
Pérez Costoya, C1
Gómez Farpón, A1
Enríquez Zarabozo, EM1
Granell Suárez, C1
Vega Mata, N1
Amat Valero, S1
Álvarez Muñoz, V1
Hussain, K1
Ahmed, M1
Masood, J1
Rafiq, MS1
Khan, MM1
Khan, A1
Jan, H1
Vahdad, MR1
Nissen, M1
Semaan, A1
Klein, T1
Palade, E1
Boemers, T1
Foroutan, HR1
Troebs, RB1
Cernaianu, G1
van Hulsteijn, LT1
Mieog, JS1
Zwartbol, MH1
Merkus, JW1
van Nieuwkoop, C1
Tuduri, I1
Leeuwenburgh, MM1
Monpellier, V1
Vlaminckx, BJ1
Go, PM1
Hussain, MI1
Alam, MK1
Al-Qahatani, HH1
Al-Akeely, MH1
Flint, R1
Mui, LM1
Ng, CS1
Wong, SK1
Lam, YH1
Fung, TM1
Fok, KL1
Chung, SS1
Ng, EK1
Zerem, E1
Salkic, N1
Imamovic, G1
Terzić, I1
Khan, MN1
Vidya, R1
Lee, RE1
Saario, I1
Arvilommi, H1
Silvola, H1
Putz, A1
Bogesits, R1
Müller, W1
Werner, C1
Söderquist-Elinder, C1
Hirsch, K1
Bergdahl, S1
Rutqvist, J1
Frenckner, B1
Ohlin, B1
Cederberg, A1
Forssell, H1
Solhaug, JH1
Tveit, E1
Thomson, SR1
Carle, G1
Reid, TM1
Davidson, AI1
Miller, SS1
Hallerbäck, B1
Andersson, C1
Englund, N1
Glise, H1
Nihlberg, A1
Solhaug, J1
Wahlström, B1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Prophylaxis With Single Versus Five Dose of Antibiotic Therapy as Treatment of Patients With Gangrenous Acute Appendicitis (Randomized, Controlled Clinical Trial)[NCT01115153]150 participants (Actual)Interventional2007-12-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

10 trials available for cefuroxime and Appendicitis

ArticleYear
Evaluation of postoperative antibiotics after non-perforated appendectomy.
    JPMA. The Journal of the Pakistan Medical Association, 2015, Volume: 65, Issue:8

    Topics: Adolescent; Adult; Anti-Bacterial Agents; Antibiotic Prophylaxis; Appendectomy; Appendicitis; Cefuro

2015
Role of postoperative antibiotics after appendectomy in non-perforated appendicitis.
    Journal of the College of Physicians and Surgeons--Pakistan : JCPSP, 2012, Volume: 22, Issue:12

    Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Antibiotic Prophylaxis; Appendectomy; Appendi

2012
Optimum duration of prophylactic antibiotics in acute non-perforated appendicitis.
    ANZ journal of surgery, 2005, Volume: 75, Issue:6

    Topics: Adolescent; Adult; Aged; Anti-Bacterial Agents; Anti-Infective Agents; Antibiotic Prophylaxis; Appen

2005
Comparison of therapeutic effectiveness of percutaneous drainage with antibiotics versus antibiotics alone in the treatment of periappendiceal abscess: is appendectomy always necessary after perforation of appendix?
    Surgical endoscopy, 2007, Volume: 21, Issue:3

    Topics: Abscess; Adult; Ampicillin; Anti-Bacterial Agents; Appendectomy; Appendicitis; Cefuroxime; Combined

2007
Comparison of cefuroxime and gentamicin in combination with metronidazole in the treatment of peritonitis due to perforation of the appendix.
    Acta chirurgica Scandinavica, 1983, Volume: 149, Issue:4

    Topics: Adult; Appendicitis; Bacteria; Cefuroxime; Cephalosporins; Clinical Trials as Topic; Drug Therapy, C

1983
[Laparoscopic appendectomy as a routine procedure].
    Infection, 1993, Volume: 21 Suppl 1

    Topics: Adolescent; Adult; Aged; Ampicillin; Appendectomy; Appendicitis; Appendix; Cefazolin; Cefuroxime; Ch

1993
Prophylactic antibiotics in uncomplicated appendicitis during childhood--a prospective randomised study.
    European journal of pediatric surgery : official journal of Austrian Association of Pediatric Surgery ... [et al] = Zeitschrift fur Kinderchirurgie, 1995, Volume: 5, Issue:5

    Topics: Adolescent; Anti-Bacterial Agents; Antibiotic Prophylaxis; Appendicitis; Appendix; Bacterial Infecti

1995
Piperacillin/tazobactam compared with cefuroxime/ metronidazole in the treatment of intra-abdominal infections.
    The European journal of surgery = Acta chirurgica, 1999, Volume: 165, Issue:9

    Topics: Abdominal Abscess; Appendicitis; Bacterial Infections; beta-Lactamase Inhibitors; Cefuroxime; Drug T

1999
Antibiotic prophylaxis in non-perforated appendicitis of childhood: tetracycline lavage compared with peroperative intravenous cefuroxime and metronidazole.
    The Journal of hospital infection, 1987, Volume: 9, Issue:2

    Topics: Adolescent; Anti-Bacterial Agents; Appendicitis; Cefuroxime; Child; Child, Preschool; Female; Humans

1987
A prospective randomized study of continuous peritoneal lavage postoperatively in the treatment of purulent peritonitis.
    Surgery, gynecology & obstetrics, 1986, Volume: 163, Issue:5

    Topics: Adult; Aged; Appendicitis; Bacterial Infections; Cefuroxime; Child; Clinical Trials as Topic; Coloni

1986

Other Studies

8 other studies available for cefuroxime and Appendicitis

ArticleYear
Analysis of a clinical guideline for treatment and early discharge in complicated acute appendicitis.
    Cirugia pediatrica : organo oficial de la Sociedad Espanola de Cirugia Pediatrica, 2023, Jul-01, Volume: 36, Issue:3

    Topics: Amoxicillin-Potassium Clavulanate Combination; Anti-Bacterial Agents; Appendectomy; Appendicitis; Ce

2023
Left sided Amyand's hernia.
    Journal of the College of Physicians and Surgeons--Pakistan : JCPSP, 2014, Volume: 24, Issue:1

    Topics: Adult; Anti-Bacterial Agents; Appendectomy; Appendicitis; Appendix; Cefuroxime; Hernia, Inguinal; Hu

2014
Experiences with LESS-appendectomy in Children.
    Archives of Iranian medicine, 2016, Volume: 19, Issue:1

    Topics: Abdominal Abscess; Adolescent; Anti-Bacterial Agents; Appendectomy; Appendicitis; Cefuroxime; Child;

2016
Appendicitis Presenting As Cellulitis of the Right Leg.
    The Journal of emergency medicine, 2017, Volume: 52, Issue:1

    Topics: Aged; Anti-Bacterial Agents; Appendicitis; Cefuroxime; Cellulitis; Emergency Service, Hospital; Esch

2017
Considerations about the article by St. Peter "Single daily dosing ceftriaxone and metronidazole vs standard triple antibiotic regimen for perforated appendicitis in children: a prospective randomised trial". J Pediatr Surg 2008;43:981-985.
    Journal of pediatric surgery, 2008, Volume: 43, Issue:10

    Topics: Abdominal Abscess; Appendicitis; Cefoxitin; Ceftriaxone; Cefuroxime; Child; Community-Acquired Infec

2008
Streptococcus milleri in intraabdominal abscesses in children after appendectomy: incidence and course.
    Journal of pediatric surgery, 2012, Volume: 47, Issue:3

    Topics: Abdominal Abscess; Adolescent; Anti-Bacterial Agents; Appendectomy; Appendicitis; Cefuroxime; Child;

2012
Appendiceal diverticulitis and actinomycosis.
    The New Zealand medical journal, 2002, Jun-07, Volume: 115, Issue:1155

    Topics: Actinomycosis; Adult; Anti-Infective Agents; Appendicitis; Cefuroxime; Diagnosis, Differential; Dive

2002
Are routine peritoneal fluid cultures during appendicectomy justified?
    Irish journal of medical science, 2007, Volume: 176, Issue:1

    Topics: Abdominal Abscess; Abdominal Cavity; Adolescent; Adult; Anti-Bacterial Agents; Antibiotic Prophylaxi

2007