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cefuroxime and Agranulocytosis

cefuroxime has been researched along with Agranulocytosis in 6 studies

Cefuroxime: Broad-spectrum cephalosporin antibiotic resistant to beta-lactamase. It has been proposed for infections with gram-negative and gram-positive organisms, GONORRHEA, and HAEMOPHILUS.
cefuroxime : A 3-(carbamoyloxymethyl)cephalosporin compound having a 7-(2Z)-2-(furan-2-yl)-2-(methoxyimino)acetamido side chain.

Agranulocytosis: A decrease in the number of GRANULOCYTES; (BASOPHILS; EOSINOPHILS; and NEUTROPHILS).

Research Excerpts

ExcerptRelevanceReference
" Using pharmacokinetic parameters of the plasma concentrations in vivo and those of the Hill equation the corresponding time course of ER was calculated and by integration with respect to time (0tERdt), an estimate was obtained of the effect on bacteria."1.28Antibacterial activity of four cephalosporins in an experimental infection in relation to in vitro effect and pharmacokinetics. ( Brus-Weijer, L; Krul, AM; Mattie, H; van Dokkum, AM; van Strijen, E, 1990)
"Neutropenia is an occasional complication of treatment with cephalosporin antibiotics."1.27Cephalosporin-induced immune neutropenia. ( Amess, JA; Green, AR; Grint, PC; Knowles, S; Metcalfe, P; Murphy, MF; Waters, AH, 1985)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19902 (33.33)18.7374
1990's3 (50.00)18.2507
2000's1 (16.67)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Grgurević, I1
Pejsa, V1
Morović-Vergles, J1
Dobrić, I1
Gasparović, V1
Tudorić, N1
Timmis, AD1
Crofts, MA1
Metcalfe, J1
Monaghan, MJ1
Sharp, J1
Jackson, G1
Erjavec, Z1
de Vries-Hospers, HG1
van Kamp, H1
van der Waaij, D1
Halie, MR1
Daenen, SM1
Hui, CH1
Chan, LC1
Mattie, H1
van Dokkum, AM1
Brus-Weijer, L1
Krul, AM1
van Strijen, E1
Murphy, MF1
Metcalfe, P1
Grint, PC1
Green, AR1
Knowles, S1
Amess, JA1
Waters, AH1

Trials

1 trial available for cefuroxime and Agranulocytosis

ArticleYear
Comparison of imipenem versus cefuroxime plus tobramycin as empirical therapy for febrile granulocytopenic patients and efficacy of vancomycin and aztreonam in case of failure.
    Scandinavian journal of infectious diseases, 1994, Volume: 26, Issue:5

    Topics: Adolescent; Adult; Aged; Agranulocytosis; Aztreonam; Cefuroxime; Drug Therapy, Combination; Female;

1994

Other Studies

5 other studies available for cefuroxime and Agranulocytosis

ArticleYear
Fatal toxic epidermal necrolysis and severe granulocytopenia following therapy with cefuroxime.
    Acta dermatovenerologica Croatica : ADC, 2008, Volume: 16, Issue:3

    Topics: Aged; Agranulocytosis; Anti-Bacterial Agents; Cefuroxime; Fatal Outcome; Female; Humans; Kidney Fail

2008
Gonococcal endocarditis with penicillin-induced bone marrow hypoplasia. Role of echocardiography.
    JAMA, 1981, Aug-07, Volume: 246, Issue:6

    Topics: Adolescent; Agranulocytosis; Bone Marrow; Cefuroxime; Echocardiography; Endocarditis, Bacterial; Fem

1981
Agranulocytosis associated with cephalosporin.
    BMJ (Clinical research ed.), 1993, Aug-21, Volume: 307, Issue:6902

    Topics: Adolescent; Agranulocytosis; Ceftazidime; Cefuroxime; Humans; Male

1993
Antibacterial activity of four cephalosporins in an experimental infection in relation to in vitro effect and pharmacokinetics.
    The Journal of infectious diseases, 1990, Volume: 162, Issue:3

    Topics: Agranulocytosis; Animals; Cefamandole; Ceftazidime; Ceftriaxone; Cefuroxime; Cephalosporins; Disease

1990
Cephalosporin-induced immune neutropenia.
    British journal of haematology, 1985, Volume: 59, Issue:1

    Topics: Adult; Agranulocytosis; Antibodies; Cefotaxime; Cefuroxime; Cephalosporins; Female; Fluorescent Anti

1985