ceftobiprole and Respiratory-Tract-Infections

ceftobiprole has been researched along with Respiratory-Tract-Infections* in 1 studies

Other Studies

1 other study(ies) available for ceftobiprole and Respiratory-Tract-Infections

Article	Year
In vitro susceptibility testing of ceftobiprole against 880 European respiratory tract infection isolates of methicillin-resistant Staphylococcus aureus followed by whole genome sequencing of ceftobiprole-resistant isolates. Diagnostic microbiology and infectious disease, 2020, Volume: 96, Issue:4 Ceftobiprole was active (MIC, ≤2 mg/L) against most isolates (99.7%; 877/880) of methicillin-resistant Staphylococcus aureus from respiratory tract infections collected in 14 European countries during 2016-2017. Whole-genome sequence analysis showed that two of the three ceftobiprole-resistant (MIC, 4 mg/L) isolates identified were clonal complex 8 (CC8) and one was CC5, and that different mutations were present in genes encoding penicillin-binding proteins, mecA, and other proteins in each ceftobiprole-resistant isolate. Topics: Anti-Bacterial Agents; Bacterial Proteins; Cephalosporins; Drug Resistance, Bacterial; Europe; Genome, Bacterial; Humans; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Mutation; Penicillin-Binding Proteins; Respiratory Tract Infections; Staphylococcal Infections; Whole Genome Sequencing	2020

Article

Year

In vitro susceptibility testing of ceftobiprole against 880 European respiratory tract infection isolates of methicillin-resistant Staphylococcus aureus followed by whole genome sequencing of ceftobiprole-resistant isolates.

Diagnostic microbiology and infectious disease, 2020, Volume: 96, Issue:4

Ceftobiprole was active (MIC, ≤2 mg/L) against most isolates (99.7%; 877/880) of methicillin-resistant Staphylococcus aureus from respiratory tract infections collected in 14 European countries during 2016-2017. Whole-genome sequence analysis showed that two of the three ceftobiprole-resistant (MIC, 4 mg/L) isolates identified were clonal complex 8 (CC8) and one was CC5, and that different mutations were present in genes encoding penicillin-binding proteins, mecA, and other proteins in each ceftobiprole-resistant isolate.

Topics: Anti-Bacterial Agents; Bacterial Proteins; Cephalosporins; Drug Resistance, Bacterial; Europe; Genome, Bacterial; Humans; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Mutation; Penicillin-Binding Proteins; Respiratory Tract Infections; Staphylococcal Infections; Whole Genome Sequencing

2020