cefsulodin and Burns

cefsulodin has been researched along with Burns* in 2 studies

Other Studies

2 other study(ies) available for cefsulodin and Burns

Article	Year
[Experimental animal studies of the healing of burn wounds with the use of local antimicrobials and hyperbaric O2 therapy]. Zeitschrift fur experimentelle Chirurgie, Transplantation, und kunstliche Organe : Organ der Sektion Experimentelle Chirurgie der Gesellschaft fur Chirurgie der DDR, 1989, Volume: 22, Issue:1 Standardized burns without experimental infection and such with infection by a constant number of bacteria of a fixed Pseudomonas-aeruginosa-strain were treated differently. Silver sulfadiazine- and Cefsulodin-cream, Polyvidon-iodine-ointment (PVP-Jod), and hyperbaric oxygen (OHP) were used to them. The courses of healing were checked by determination of the wound area daily. The best results showed the experimental uninfected untreated wounds. Wounds infected by Pseudomonas were healing most quickly by immediate and continuous application of hyperbaric oxygen. By silver sulfadiazine- and Cefsulodin-cream treated burns showed statistical significant better results than the control group. The courses of healing were significantly poorer in delayed application of OHP (only from the 8th day after the burn) or in case of therapy with PVP-iodine alone. Topics: Administration, Topical; Animals; Burns; Cefsulodin; Female; Guinea Pigs; Hyperbaric Oxygenation; Ointments; Povidone-Iodine; Pseudomonas Infections; Silver Sulfadiazine; Wound Healing; Wound Infection	1989
[Clinical application of cefsulodin to Pseudomonas aeruginosa infections in the surgical field (author's transl)]. The Japanese journal of antibiotics, 1981, Volume: 34, Issue:4 Cefsulodin (CFS), a new antipseudomonas cephalosporin, was clinically evaluated for treatment of the Pseudomonas aeruginosa infections in the surgical field to obtain the following results. 1. CFS was administered to total 11 cases of the surgical infections caused by P. aeruginosa, comprising of 5 cases with wound infections, 3 cases with infected burn and 1 case each with muscular abscess, decubitus and postoperative pneumonia in 0.5 approximately 1 g twice a day by intravenous bolus or drip infusion. Good clinical responses were obtained in 9 out of 11 cases (81.8%). 2. Bacteriological responses were observed in all cases. P. aeruginosa was eradicated in 9 cases and suppressed in 2 cases by CFS treatment. However, replacement of pathogens with the other organisms was observed in 6 out of 8 cases caused by P. aeruginosa only. 3. Neither objective and subjective side effects nor abnormalities of laboratory tests associated with CFS treatment were observed. 4. It can be, therefore, concluded that CFS is one of the useful drugs for treatment of the surgical infections caused by P. aeruginosa. Topics: Adult; Aged; Burns; Cefsulodin; Cephalosporins; Child; Drug Evaluation; Female; Humans; Male; Middle Aged; Pseudomonas Infections; Surgical Wound Infection	1981

Article

Year

[Experimental animal studies of the healing of burn wounds with the use of local antimicrobials and hyperbaric O2 therapy].

Zeitschrift fur experimentelle Chirurgie, Transplantation, und kunstliche Organe : Organ der Sektion Experimentelle Chirurgie der Gesellschaft fur Chirurgie der DDR, 1989, Volume: 22, Issue:1

Standardized burns without experimental infection and such with infection by a constant number of bacteria of a fixed Pseudomonas-aeruginosa-strain were treated differently. Silver sulfadiazine- and Cefsulodin-cream, Polyvidon-iodine-ointment (PVP-Jod), and hyperbaric oxygen (OHP) were used to them. The courses of healing were checked by determination of the wound area daily. The best results showed the experimental uninfected untreated wounds. Wounds infected by Pseudomonas were healing most quickly by immediate and continuous application of hyperbaric oxygen. By silver sulfadiazine- and Cefsulodin-cream treated burns showed statistical significant better results than the control group. The courses of healing were significantly poorer in delayed application of OHP (only from the 8th day after the burn) or in case of therapy with PVP-iodine alone.

Topics: Administration, Topical; Animals; Burns; Cefsulodin; Female; Guinea Pigs; Hyperbaric Oxygenation; Ointments; Povidone-Iodine; Pseudomonas Infections; Silver Sulfadiazine; Wound Healing; Wound Infection

1989

[Clinical application of cefsulodin to Pseudomonas aeruginosa infections in the surgical field (author's transl)].

The Japanese journal of antibiotics, 1981, Volume: 34, Issue:4

Cefsulodin (CFS), a new antipseudomonas cephalosporin, was clinically evaluated for treatment of the Pseudomonas aeruginosa infections in the surgical field to obtain the following results. 1. CFS was administered to total 11 cases of the surgical infections caused by P. aeruginosa, comprising of 5 cases with wound infections, 3 cases with infected burn and 1 case each with muscular abscess, decubitus and postoperative pneumonia in 0.5 approximately 1 g twice a day by intravenous bolus or drip infusion. Good clinical responses were obtained in 9 out of 11 cases (81.8%). 2. Bacteriological responses were observed in all cases. P. aeruginosa was eradicated in 9 cases and suppressed in 2 cases by CFS treatment. However, replacement of pathogens with the other organisms was observed in 6 out of 8 cases caused by P. aeruginosa only. 3. Neither objective and subjective side effects nor abnormalities of laboratory tests associated with CFS treatment were observed. 4. It can be, therefore, concluded that CFS is one of the useful drugs for treatment of the surgical infections caused by P. aeruginosa.

Topics: Adult; Aged; Burns; Cefsulodin; Cephalosporins; Child; Drug Evaluation; Female; Humans; Male; Middle Aged; Pseudomonas Infections; Surgical Wound Infection

1981