cefpodoxime-proxetil and Soft-Tissue-Infections

The authors present their experience with antimicrobial treatment with cephalosporin of the third generation, cefpodoxime proxetil, in skin and soft tissue infections in a group of patients treated at the ambulatory department of the Surgical Clinic in Prague 10 in 1995. From the total number antimicrobial treatment was administered to 6 patients with a phlegmon, 5 patients with panaritium, 4 patients with an early infection after laparotomy, 3 with an abscess in the subcutaneous layer, and with cheilitis and bursitis of the olecranon in the remaining two patients. In addition to surgical treatment (incision, evacuation and drainage) cefpodoxime proxetil-200 mg after 12-hour intervals for 6-9 days-was administered to the patients. For microbiological examination a smear from the inflammatory focus and from the nasopharynx was used. The cefpodoxime proxetil serum level was assessed during the 1st-11th hour after administration of the antibiotic. All 20 patients recovered.

Topics: Adolescent; Adult; Aged; Aged, 80 and over; Bacterial Infections; Cefpodoxime Proxetil; Ceftizoxime; Female; Humans; Male; Middle Aged; Prodrugs; Skin Diseases, Bacterial; Soft Tissue Infections

Topics: Bacteria; Bacterial Infections; Cefpodoxime Proxetil; Ceftizoxime; Cephalosporins; Child; Child, Preschool; Female; Humans; Infant; Male; Microbial Sensitivity Tests; Prodrugs; Skin Diseases, Infectious; Soft Tissue Infections