cefoxitin and Leukemia--Lymphocytic--Chronic--B-Cell

Immunophenotyping of peripheral blood lymphocytes from six patients with B-cell chronic lymphocytic leukemia (B-CLL) and five normal volunteers was done and their T and Tn epitopes analyzed using specific monoclonal antibodies and flow cytometry. Lymphocytes from all patients showed strong Tn expression as compared to normal control lymphocytes. By contrast, T antigen was not expressed, The TN expression may be a useful diagnostic and prognostic marker for B-CLL.

Topics: Adult; Aged; Antigens, CD; Antigens, Neoplasm; Antigens, Tumor-Associated, Carbohydrate; B-Lymphocytes; Biomarkers, Tumor; Epitopes; Female; Flow Cytometry; Humans; Immunophenotyping; Leukemia, Lymphocytic, Chronic, B-Cell; Male; Middle Aged; Neoplastic Stem Cells