cefoxitin and Clostridium-Infections

Cycloserine-cefoxitin fructose agar (CCFA), CCFA with horse blood and taurocholate (CCFA-HT), and cycloserine-cefoxitin mannitol broth with taurocholate and lysozyme (CCMB-TAL) were compared for recovery of Clostridium difficile from 120 stool specimens. Compared to CCFA, CCFA-HT enhanced C. difficile growth and improved recovery by 4%. In a separate study, 9% (8/91) of stool samples previously C. difficile negative on plate medium were C. difficile positive when cultured in CCMB-TAL.

Topics: Agar; Animals; Anti-Infective Agents; Cefoxitin; Clostridioides difficile; Clostridium Infections; Culture Media; Cycloserine; Erythrocytes; Feces; Fructose; Horses; Humans; Mannitol; Muramidase; Taurocholic Acid

Cycloserine-Cefoxitin-Fructose Agar (CCFA) gives good presumptive identification of Clostridium difficile after 1- or 2-day incubation whereas Reinforced Clostridial Medium (RCM)/p-cresol is not very selective for the organism from the vagina. The identification of 91.5% of the isolates from an initial screen subjected to biochemically based tests was achieved. Conventional screening of vaginal swabs failed to confirm any significant occurrence of Cl. difficile in the vagina of pregnant or non-pregnant women. The incorporation of an enrichment stage in the isolation procedure, however, did reveal a significant presence of the organism in the vagina of both pregnant and non-pregnant women.

Topics: Carrier State; Cefoxitin; Clostridium; Clostridium Infections; Cresols; Culture Media; Cycloserine; Female; Fructose; Humans; Pregnancy; Pregnancy Complications, Infectious; Scotland; Vagina

Topics: Cefoxitin; Clostridium Infections; Clostridium perfringens; Empyema; Humans; Male; Middle Aged; Penicillin G; Penicillin Resistance

Topics: Adult; Cefoxitin; Clostridium Infections; Female; Humans; Liver Cirrhosis; Peritonitis

Topics: Adolescent; Blood Coagulation Tests; Cefoxitin; Clostridium Infections; Disseminated Intravascular Coagulation; Drug Therapy, Combination; Female; Gentamicins; Heparin; Humans; Sepsis