cefotaxime and Skin-Ulcer

Nosocomial aspiration pneumonia and infections of soft tissue are most often caused by mixed aerobic and anaerobic pathogens. Single-agent therapy with a beta-lactam antibiotic is tending to replace combination therapy because it is as effective and less toxic. Important considerations in choosing among the beta-lactam antibiotics include a long pharmacologic half-life, permitting less frequent administration, and cost per gram.

Topics: Cefazolin; Cefotaxime; Ceftizoxime; Cost Control; Cross Infection; Diabetes Complications; Half-Life; Humans; Pneumonia, Aspiration; Skin Ulcer

In the course of a study to determine the nature and type of secondary bacterial infection in dracunculiasis. The most common organisms cultured from lesions were Escherichia coli, Enterobacter and Staphylococcus aureus. E. coli and Enterobacter which were found to carry high morbidity were sensitive to Gentamycin, Claforan and Septrin.

Topics: Cefotaxime; Dracunculiasis; Drug Combinations; Enterobacter; Enterobacteriaceae Infections; Escherichia coli; Escherichia coli Infections; Female; Gentamicins; Humans; Skin Diseases, Infectious; Skin Ulcer; Staphylococcal Skin Infections; Staphylococcus aureus; Sulfamethoxazole; Trimethoprim; Trimethoprim, Sulfamethoxazole Drug Combination