cefotaxime and Pneumonia--Aspiration

Nosocomial aspiration pneumonia and infections of soft tissue are most often caused by mixed aerobic and anaerobic pathogens. Single-agent therapy with a beta-lactam antibiotic is tending to replace combination therapy because it is as effective and less toxic. Important considerations in choosing among the beta-lactam antibiotics include a long pharmacologic half-life, permitting less frequent administration, and cost per gram.

Topics: Cefazolin; Cefotaxime; Ceftizoxime; Cost Control; Cross Infection; Diabetes Complications; Half-Life; Humans; Pneumonia, Aspiration; Skin Ulcer