cefotaxime and Endocarditis

Prevotella species (i. e. P. intermedia, P. nigrescens, P. pallens, P. oris) are usually responsible for abscesses of head and neck spaces after dental procedures. P. intermedia - related infective endocarditis has never been reported.. A 22-year-old man, with a history of aortic valve replacement 6 years ago, presented with fever and persistent retrosternal chest pain. An empirical antibiotic therapy was started on (cefotaxime, 2gx3 - gentamicin, 5mg/kilo). Five blood cultures were positive at Prevotella Intermedia. Metronidazole was introduced (500mg X 3 by day).The oro-pharyngeal spaces were normal. The evolution was marked by a hypotension, a third degree atrio-ventricular block, and a rapidly growing aortic root abscess complicated this case of Prevotella Intermedia infective endocarditis (IE). Aortic valve redux surgery was performed at day 5 of admission. Post-operative course was unremarkable.. This first reported case of Prevotella Intermedia IE presented suggestive features of anaerobic IE as the patient developed both aortic-ring abscess, third degree atrio-ventricular block and hypotension.

Topics: Abscess; Adult; Anti-Bacterial Agents; Aortic Valve; Cefotaxime; Endocarditis; Endocarditis, Bacterial; Gentamicins; Heart Valve Prosthesis; Humans; Hypotension; Male; Metronidazole; Prevotella intermedia; Young Adult

Topics: Blindness; Cefotaxime; Endocarditis; Endophthalmitis; Humans; Intravitreal Injections; Male; Meningitis; Middle Aged; Pneumonia; Sepsis; Streptococcal Infections; Streptococcus pneumoniae

Topics: Anti-Bacterial Agents; Cefazolin; Cefotaxime; Emphysema; Endocarditis; Endophthalmitis; Escherichia coli Infections; Fatal Outcome; Gentamicins; Humans; Male; Middle Aged; Oxacillin; Sepsis; Urinary Tract Infections