cefotaxime and Conjunctivitis--Bacterial

Soft tissue involvement is an unusual presenting feature for children with meningococcal infection. We describe 2 children, 1 with conjunctivitis and another with a thyroglossal duct cyst abscess associated with Neisseria meningitidis, and review previous reports of these entities to emphasize the broad spectrum of meningococcal disease and pertinent aspects of treatment and of prophylaxis of contacts.

Topics: Abscess; Anti-Bacterial Agents; Cefotaxime; Child; Conjunctivitis, Bacterial; Humans; Infant; Male; Meningococcal Infections; Neisseria meningitidis; Thyroglossal Cyst

Topics: Amoxicillin; Amoxicillin-Potassium Clavulanate Combination; Cefotaxime; Cellulitis; Clavulanic Acids; Conjunctivitis, Acute Hemorrhagic; Conjunctivitis, Bacterial; Drug Therapy, Combination; Female; Haemophilus Infections; Haemophilus influenzae; Humans; Infant; Male

In a private pediatric practice setting 114 episodes of conjunctivitis-otitis syndrome were treated with orally administered antibiotics. In 108 (95%) of these infections Haemophilus influenzae was isolated from the pretreatment cultures of the conjunctivae; 61 were susceptible and 47 (44%) were resistant to ampicillin by a disc diffusion technique. Six cultures grew Streptococcus pneumoniae, all ampicillin-susceptible. Symptoms of conjunctivitis disappeared in 2 to 3 days in all but one patient. Of the 48 follow-up conjunctival cultures 3 to 5 days after start of therapy, 46 grew no pathogens.

Topics: Administration, Oral; Ampicillin; Anti-Bacterial Agents; Cefaclor; Cefixime; Cefotaxime; Child; Child, Preschool; Conjunctivitis, Bacterial; Haemophilus Infections; Haemophilus influenzae; Humans; Infant; Microbial Sensitivity Tests; Otitis Media; Streptococcus pneumoniae

Two and a half weeks after a 62-year-old man underwent bilateral nasolacrimal intubation with silicone tubes, canaliculitis and conjunctivitis developed. Cultures yielded Mycobacterium chelonae sensitive to amikacin. Successful therapy required removal of the tubes followed by intensive intravenous and topical chemotherapy. This is, to our knowledge, the first report of mycobacterial infection as a complication of lacrimal intubation.

Topics: Amikacin; Cefotaxime; Conjunctivitis, Bacterial; Humans; Intubation; Lacrimal Duct Obstruction; Male; Middle Aged; Mycobacterium Infections; Reoperation; Silicone Elastomers