cefotaxime has been researched along with Cataract* in 5 studies
5 other study(ies) available for cefotaxime and Cataract
Article | Year |
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Presumed endogenous Klebsiella pneumonia endophthalmitis in a premature infant.
Topics: Anti-Bacterial Agents; Cataract; Cefotaxime; Endophthalmitis; Eye Infections, Bacterial; Female; Gestational Age; Humans; Infant, Newborn; Infant, Premature, Diseases; Infant, Very Low Birth Weight; Klebsiella Infections; Klebsiella pneumoniae; Ultrasonography | 2004 |
[Cefotiam level in human eyes after subconjunctival injection].
Topics: Adult; Aged; Aged, 80 and over; Aqueous Humor; Cataract; Cefotaxime; Cefotiam; Eye; Female; Glaucoma, Open-Angle; Humans; Injections; Iris; Male; Middle Aged; Tissue Distribution | 1987 |
Pharmacokinetic analysis of intravitreal ceftriaxone in monkeys.
Ocular toxic effects of intravitreally injected ceftriaxone sodium and its rate of clearance after a single dose were studied in rhesus and cynomolgus monkeys. Doses of 2, 2.5, and 3 mg/0.1 mL were injected into the vitreous cavity. Electroretinograms performed 15 minutes, 24 hours, one week, and two weeks after injection were not significantly different from preinjection electroretinograms. Lens opacification occurred in one eye receiving 2.5 mg of ceftriaxone. Histopathologic findings in the retina were normal in all eyes injected intravitreally. Levels of ceftriaxone after a 2-mg intravitreal dose were 609 mg/L at 0 hours, 434 mg/L at 24 hours, and 19 mg/L at 100 hours in the vitreous; and 1 mg/L at 0 hours, 116 mg/L at 24 hours, and 9 mg/L at 100 hours in the aqueous. Topics: Animals; Aqueous Humor; Cataract; Cefotaxime; Ceftriaxone; Electroretinography; Female; Kinetics; Macaca fascicularis; Macaca mulatta; Male; Vitreous Body | 1985 |
Intraocular penetration of cefmenoxime (SCE-1365), A new cephalosporin, in humans.
Topics: Adult; Aged; Aqueous Humor; Cataract; Cefmenoxime; Cefotaxime; Female; Humans; Injections, Intravenous; Male; Middle Aged | 1982 |
[The studies on distributions of cefsulodin and cefotiam to human aqueous humor and cornea].
Distributions of cefsulodin (CFS) and cefotiam (CTM), new parenteral cephalosporins, to human aqueous humor and cornea were studied in comparison with those of sulbenicillin (SBPC) and cefazolin (CEZ), and pharmacokinetic analysis was made by theory of compartment model, to obtain the following results. 1. Maximum aqueous humor levels of CFS and CTM were noticed at 2.5 hours after the start of 1 g CFS or CTM administration by 30 minute intravenous drip infusion, with the levels of 3.6 micrograms/ml and 4.2 micrograms/ml respectively. On the other hand, in case of 5 g SBPC or 2 g CEZ administration maximum aqueous humor levels were 12.5 micrograms/ml and 5.2 micrograms/ml respectively. 2. The ratios of maximum aqueous humor level to plasma level of the same time in CFS, CTM, SBPC and CEZ were 15.0, 16.8, 6.4% and 5.5%. Distribution of CFS or CTM was 2 to 3 times better than that of SBPC or CEZ. 3. From the result of pharmacokinetic analysis, ratios of aqueous humor to plasma levels in area under curves (AUC) of CFS, CTM, SBPC and CEZ were 25.6, 29.9, 16.4% and 7.9% respectively. Maximum aqueous humor levels of CFS, CTM, SBPC and CEZ were 2.9, 3.6, 11.4 micrograms/ml and 4.3 micrograms/ml and biological half life of gamma-phase were 2.57, 2.31, 2.77 hours and 2.24 hours respectively. 4. Cornea levels of CFS or CTM at one hour after the start of 1 g CFS or CTM administration by 30 minutes intravenous drip infusion were 2.9 micrograms/g and 5.2 micrograms/g, and their ratios to plasma level were 7.5% or 14.3% respectively. In case of 5 g SBPC or 2 g CEZ administration, the cornea levels were 26.7 micrograms/g and 5.0 micrograms/g, and the ratios were 9.4% and 3.4% respectively. 5. From the above, the distribution of CFS or CTM to human aqueous humor and cornea is better than that of SBPC or CEZ, and it is considered that clinical usefulness of both CFS and CTM by parenteral administration is expected in intraocular infections. Topics: Aged; Aqueous Humor; Cataract; Cefotaxime; Cefotiam; Cefsulodin; Cephalosporins; Cornea; Female; Humans; Infusions, Parenteral; Kinetics; Male; Middle Aged | 1982 |