Page last updated: 2024-10-24

cefixime and Urethritis

cefixime has been researched along with Urethritis in 12 studies

Cefixime: A third-generation cephalosporin antibiotic that is stable to hydrolysis by beta-lactamases.
cefixime : A third-generation cephalosporin antibiotic bearing vinyl and (2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-[(carboxymethoxy)imino]acetamido groups at positions 3 and 7, respectively, of the cephem skeleton. It is used in the treatment of gonorrhoea, tonsilitis, pharyngitis, bronchitis, and urinary tract infections.

Urethritis: Inflammation involving the URETHRA. Similar to CYSTITIS, clinical symptoms range from vague discomfort to painful urination (DYSURIA), urethral discharge, or both.

Research Excerpts

ExcerptRelevanceReference
"In this randomized study, a single 800-mg oral dose of cefixime cured 96 of 97 men with uncomplicated gonococcal urethritis, compared with 44 cures of 46 men who received standard therapy with amoxicillin (3 g) plus probenecid (1 g)."9.06Single-dose oral cefixime versus amoxicillin plus probenecid for the treatment of uncomplicated gonorrhea in men. ( Bowie, WR; Lefebvre, K; Megran, DW; Willetts, V, 1990)
" Subsequently, a dosing interval of 6 h was tested in 6 healthy Japanese men, and then 93 Japanese men with gonococcal urethritis were treated with a regimen of two 200-mg doses of cefixime given at a 6-h interval."5.32Treatment of uncomplicated gonococcal urethritis by double-dosing of 200 mg cefixime at a 6-h interval. ( Deguchi, T; Harada, Y; Ishida, K; Ishihara, S; Ito, M; Kojima, K; Maeda, S; Minamidate, K; Tamaki, M; Tei, K; Yasuda, M; Yokoi, S, 2003)
"In this randomized study, a single 800-mg oral dose of cefixime cured 96 of 97 men with uncomplicated gonococcal urethritis, compared with 44 cures of 46 men who received standard therapy with amoxicillin (3 g) plus probenecid (1 g)."5.06Single-dose oral cefixime versus amoxicillin plus probenecid for the treatment of uncomplicated gonorrhea in men. ( Bowie, WR; Lefebvre, K; Megran, DW; Willetts, V, 1990)
"Oral regimens for the treatment of gonorrhea are limited."2.46Emergence and spread of drug resistant Neisseria gonorrhoeae. ( Deguchi, T; Maeda, S; Nakane, K; Yasuda, M, 2010)
" Subsequently, a dosing interval of 6 h was tested in 6 healthy Japanese men, and then 93 Japanese men with gonococcal urethritis were treated with a regimen of two 200-mg doses of cefixime given at a 6-h interval."1.32Treatment of uncomplicated gonococcal urethritis by double-dosing of 200 mg cefixime at a 6-h interval. ( Deguchi, T; Harada, Y; Ishida, K; Ishihara, S; Ito, M; Kojima, K; Maeda, S; Minamidate, K; Tamaki, M; Tei, K; Yasuda, M; Yokoi, S, 2003)
"Cefixime was kept for patients not responding to the first GU treatment."1.31Cost-effectiveness of management strategies for acute urethritis in the developing world. ( Crabbé, F; de Clerck, M; Laga, M; Vuylsteke, B, 2000)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (25.00)18.2507
2000's3 (25.00)29.6817
2010's5 (41.67)24.3611
2020's1 (8.33)2.80

Authors

AuthorsStudies
Yasuda, M4
Takahashi, S3
Miyazaki, J1
Wada, K1
Kobayashi, K2
Matsumoto, M1
Hayami, H2
Yamamoto, S2
Kiyota, H3
Sato, J2
Matsumoto, T2
Yotsuyanagi, H1
Hanaki, H2
Masumori, N1
Hiyama, Y2
Nishiyama, H1
Kimura, T1
Yamada, H1
Matsumoto, K1
Ishikawa, K2
Togo, Y1
Tanaka, K2
Sadahira, T1
Inokuchi, J1
Hamasuna, R2
Ito, K2
Hirayama, H2
Hayashi, K1
Kurimura, Y2
Kadena, H2
Ito, S2
Shiono, Y1
Maruyama, T1
Ito, M3
Hatano, K1
Chokyu, H2
Ihara, H1
Uno, S2
Monden, K2
Yokoyama, T1
Kano, M2
Kaji, S2
Kawahara, M2
Sumii, T2
Tojo, T1
Hosobe, T2
Naito, K1
Kawai, S2
Nishimura, H2
Izumitani, M1
Yoh, M2
Matsumura, M2
Fujita, R1
Takayama, K2
Hara, M1
Nishi, S2
Uehara, S1
Minamitani, S1
Watanabe, A1
Iwata, S1
Kaku, M1
Kadota, J1
Sunakawa, K1
Tsukamoto, T2
Egawa, S1
Arakawa, S1
Fujisawa, M1
Kumon, H1
Matsubara, A1
Naito, S1
Kuroiwa, K1
Narita, H1
Yoshioka, M1
Yamaguchi, T1
Maeda, S3
Shirane, T1
Akiyama, K1
Imai, T1
Peters, RP1
Verweij, SP1
McIntyre, JA1
Schaftenaar, E1
Osaka, K1
Takakura, T1
Narukawa, K1
Takahata, M1
Endo, K1
Onodera, S1
Brill, JR1
Deguchi, T2
Nakane, K1
Hashimoto, J1
Uehara, T1
Iwasawa, A1
Nishimura, M1
Sunaoshi, K1
Takeda, K1
Suzuki, N1
Yokoi, S1
Ishida, K1
Ishihara, S1
Minamidate, K1
Harada, Y1
Tei, K1
Kojima, K1
Tamaki, M1
Crabbé, F1
Vuylsteke, B1
de Clerck, M1
Laga, M1
Plourde, PJ1
Tyndall, M1
Agoki, E1
Ombette, J1
Slaney, LA1
D'Costa, LJ1
Ndinya-Achola, JO1
Plummer, FA1
Asbach, HW1
Megran, DW1
Lefebvre, K1
Willetts, V1
Bowie, WR1

Reviews

1 review available for cefixime and Urethritis

ArticleYear
Emergence and spread of drug resistant Neisseria gonorrhoeae.
    The Journal of urology, 2010, Volume: 184, Issue:3

    Topics: Azithromycin; Cefixime; Drug Resistance, Bacterial; Fluoroquinolones; Gonorrhea; Humans; Neisseria g

2010

Trials

3 trials available for cefixime and Urethritis

ArticleYear
Single-dose cefixime versus single-dose ceftriaxone in the treatment of antimicrobial-resistant Neisseria gonorrhoeae infection.
    The Journal of infectious diseases, 1992, Volume: 166, Issue:4

    Topics: Administration, Oral; Adult; Aged; Anti-Bacterial Agents; Cefixime; Cefotaxime; Ceftriaxone; Drug Ev

1992
Single dose oral administration of cefixime 400mg in the treatment of acute uncomplicated cystitis and gonorrhoea.
    Drugs, 1991, Volume: 42 Suppl 4

    Topics: Acute Disease; Administration, Oral; Cefixime; Cefotaxime; Cystitis; Double-Blind Method; Female; Go

1991
Single-dose oral cefixime versus amoxicillin plus probenecid for the treatment of uncomplicated gonorrhea in men.
    Antimicrobial agents and chemotherapy, 1990, Volume: 34, Issue:2

    Topics: Adolescent; Adult; Amoxicillin; Cefixime; Cefotaxime; Gonorrhea; Humans; Male; Probenecid; Randomize

1990

Other Studies

8 other studies available for cefixime and Urethritis

ArticleYear
The third nationwide surveillance of antimicrobial susceptibility against Neisseria gonorrhoeae from male urethritis in Japan, 2016-2017.
    Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy, 2023, Volume: 29, Issue:11

    Topics: Anti-Bacterial Agents; Anti-Infective Agents; Azithromycin; Cefixime; Ceftriaxone; Gonorrhea; Humans

2023
The second nationwide surveillance of the antimicrobial susceptibility of Neisseria gonorrhoeae from male urethritis in Japan, 2012-2013.
    Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy, 2015, Volume: 21, Issue:5

    Topics: Adolescent; Adult; Aged; Anti-Bacterial Agents; Azithromycin; Cefixime; Ceftriaxone; Drug Resistance

2015
Gonococcal Conjunctivitis Despite Successful Treatment of Male Urethritis Syndrome.
    Sexually transmitted diseases, 2016, Volume: 43, Issue:2

    Topics: Anti-Bacterial Agents; Azithromycin; Cefixime; Conjunctivitis; Gonorrhea; Humans; Male; Neisseria go

2016
Analysis of amino acid sequences of penicillin-binding protein 2 in clinical isolates of Neisseria gonorrhoeae with reduced susceptibility to cefixime and ceftriaxone.
    Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy, 2008, Volume: 14, Issue:3

    Topics: Amino Acid Sequence; Anti-Bacterial Agents; beta-Lactamases; Cefixime; Ceftriaxone; Drug Resistance,

2008
Diagnosis and treatment of urethritis in men.
    American family physician, 2010, Apr-01, Volume: 81, Issue:7

    Topics: Adolescent; Adult; Azithromycin; Black or African American; Cefixime; Ceftriaxone; Chlamydia Infecti

2010
Antimicrobial susceptibility and penicillin-binding protein 1 and 2 mutations in Neisseria gonorrhoeae isolated from male urethritis in Sapporo, Japan.
    Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy, 2013, Volume: 19, Issue:1

    Topics: Anti-Bacterial Agents; Cefixime; Cephalosporin Resistance; Cephalosporins; Gonorrhea; Humans; Japan;

2013
Treatment of uncomplicated gonococcal urethritis by double-dosing of 200 mg cefixime at a 6-h interval.
    Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy, 2003, Volume: 9, Issue:1

    Topics: Anti-Bacterial Agents; Cefixime; Drug Administration Schedule; Gonorrhea; Humans; Male; Microbial Se

2003
Cost-effectiveness of management strategies for acute urethritis in the developing world.
    Tropical medicine & international health : TM & IH, 2000, Volume: 5, Issue:9

    Topics: Acute Disease; Anti-Bacterial Agents; Anti-Infective Agents; Cefixime; Cost-Benefit Analysis; Decisi

2000