cefixime has been researched along with Typhoid Fever in 25 studies
Cefixime: A third-generation cephalosporin antibiotic that is stable to hydrolysis by beta-lactamases.
cefixime : A third-generation cephalosporin antibiotic bearing vinyl and (2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-[(carboxymethoxy)imino]acetamido groups at positions 3 and 7, respectively, of the cephem skeleton. It is used in the treatment of gonorrhoea, tonsilitis, pharyngitis, bronchitis, and urinary tract infections.
Typhoid Fever: An acute systemic febrile infection caused by SALMONELLA TYPHI, a serotype of SALMONELLA ENTERICA.
| Excerpt | Relevance | Reference |
|---|---|---|
| "An intervention study was carried out in the department of paediatrics of Mymensingh Medical College Hospital, Mymensingh to compare the clinical efficacy of Azithromycin in the treatment of childhood typhoid fever with that of cefixime for a period of one year from January 2011 to December 2011." | 9.19 | Comparison between azithromycin and cefixime in the treatment of typhoid fever in children. ( Ahmed, MS; Ahsan, MM; Akhtaruzzaman, M; Begum, B; Choudhury, AM; Haque, MA; Hasan, MM; Hossain, MA; Islam, MN; Khaleque, MA; Khan, AH; Khatun, AA, 2014) |
| "To assess the efficacy of gatifloxacin versus cefixime in the treatment of uncomplicated culture positive enteric fever." | 9.12 | An open randomized comparison of gatifloxacin versus cefixime for the treatment of uncomplicated enteric fever. ( Arjyal, A; Basnyat, B; Campbell, JI; Dangol, S; Day, JN; Dolecek, C; Farrar, JJ; Pandit, A; Paudyal, B; Stepniewska, K; Yadav, B; Zimmerman, MD, 2007) |
| "In order to evaluate clinical and bacteriological efficacy of Cefpodoxime Proxetil (CP) in typhoid fever in comparison to cefixime (CF), we assessed 140 children with suspected typhoid fever." | 9.12 | Cefpodoxime proxetil compared with cefixime for treatment of typhoid fever in children. ( Ahmed, M; Arzuman, SA; Hossain, J; Mehdi, H; Shakur, MS, 2007) |
| "Cefixime, an orally administered third generation cephalosporin, was compared with ofloxacin for the treatment of uncomplicated typhoid fever in children." | 9.09 | A comparative study of ofloxacin and cefixime for treatment of typhoid fever in children. The Dong Nai Pediatric Center Typhoid Study Group. ( Cao, XT; Kneen, R; Nguyen, TA; Parry, CM; Truong, DL; White, NJ, 1999) |
| "Cefixime is a safe, effective, and cheaper oral option for the treatment of multidrug-resistant enteric fever." | 9.08 | Cefixime: an oral option for the treatment of multidrug-resistant enteric fever in children. ( Billoo, AG; Memon, HI; Memon, IA, 1997) |
| "We compared cefixime with chloramphenicol in a randomized trial for treatment of children with culture positive typhoid fever." | 9.08 | A comparative study of cefixime and chloramphenicol in children with typhoid fever. ( Iqbal, I; Malik, MS; Rabbani, W, 1998) |
| "We compared cefixime with chloramphenicol in a trial for treatment of children with culture positive typhoid fever." | 9.08 | A comparative study of cefixime and chloramphenicol in children with typhoid fever. ( Iqbal, I; Malik, MS; Rabbani, MW, 1998) |
| " However, cefixime has been shown to be clinically effective against typhoid fever." | 7.71 | Mechanism of therapeutic effectiveness of cefixime against typhoid fever. ( Ikeda, F; Ikemoto, A; Matsumoto, K; Matsumoto, Y; Tawara, S; Wakai, Y, 2001) |
| "Multi-drug resistant Typhoid fever (resistant to previously used chloramphenicol, ampicillin, amoxicillin, and trimethoprim-sulfamethoxazole) has been commonly described in the South East Asia region and a recent report suggests that the salmonella typhi have reduced response to fluoroquinolones (nalidixic acid-resistant)." | 7.01 | Open Label Randomized Controlled Comparison of Three Alternative Regimes of Ciprofloxacin, Azithromycin and Cefixime for Treatment of Uncomplicated Typhoid Fever in Bangladesh. ( Ahmed, SM; Amin, MR; Das, SK; Hasan, MJ; Islam, MR; Kabir, A, 2021) |
| "In 9 cases the typhoidal organisms isolated were susceptible to first-line drugs." | 6.67 | Therapy of multidrug-resistant typhoid fever with oral cefixime vs. intravenous ceftriaxone. ( Bhutta, ZA; Khan, IA; Molla, AM, 1994) |
| "Cefixime proved to be an effective oral drug in this open treatment trial and was associated with minimal side effects." | 5.29 | Cefixime in the treatment of enteric fever in children. ( Farid, Z; Girgis, NI; Kilpatrick, ME; Podgore, JK; Sultan, Y, 1993) |
| "An intervention study was carried out in the department of paediatrics of Mymensingh Medical College Hospital, Mymensingh to compare the clinical efficacy of Azithromycin in the treatment of childhood typhoid fever with that of cefixime for a period of one year from January 2011 to December 2011." | 5.19 | Comparison between azithromycin and cefixime in the treatment of typhoid fever in children. ( Ahmed, MS; Ahsan, MM; Akhtaruzzaman, M; Begum, B; Choudhury, AM; Haque, MA; Hasan, MM; Hossain, MA; Islam, MN; Khaleque, MA; Khan, AH; Khatun, AA, 2014) |
| "To assess the efficacy of gatifloxacin versus cefixime in the treatment of uncomplicated culture positive enteric fever." | 5.12 | An open randomized comparison of gatifloxacin versus cefixime for the treatment of uncomplicated enteric fever. ( Arjyal, A; Basnyat, B; Campbell, JI; Dangol, S; Day, JN; Dolecek, C; Farrar, JJ; Pandit, A; Paudyal, B; Stepniewska, K; Yadav, B; Zimmerman, MD, 2007) |
| "In order to evaluate clinical and bacteriological efficacy of Cefpodoxime Proxetil (CP) in typhoid fever in comparison to cefixime (CF), we assessed 140 children with suspected typhoid fever." | 5.12 | Cefpodoxime proxetil compared with cefixime for treatment of typhoid fever in children. ( Ahmed, M; Arzuman, SA; Hossain, J; Mehdi, H; Shakur, MS, 2007) |
| "Cefixime, an orally administered third generation cephalosporin, was compared with ofloxacin for the treatment of uncomplicated typhoid fever in children." | 5.09 | A comparative study of ofloxacin and cefixime for treatment of typhoid fever in children. The Dong Nai Pediatric Center Typhoid Study Group. ( Cao, XT; Kneen, R; Nguyen, TA; Parry, CM; Truong, DL; White, NJ, 1999) |
| "Cefixime is a safe, effective, and cheaper oral option for the treatment of multidrug-resistant enteric fever." | 5.08 | Cefixime: an oral option for the treatment of multidrug-resistant enteric fever in children. ( Billoo, AG; Memon, HI; Memon, IA, 1997) |
| "We compared cefixime with chloramphenicol in a randomized trial for treatment of children with culture positive typhoid fever." | 5.08 | A comparative study of cefixime and chloramphenicol in children with typhoid fever. ( Iqbal, I; Malik, MS; Rabbani, W, 1998) |
| "We compared cefixime with chloramphenicol in a trial for treatment of children with culture positive typhoid fever." | 5.08 | A comparative study of cefixime and chloramphenicol in children with typhoid fever. ( Iqbal, I; Malik, MS; Rabbani, MW, 1998) |
| "Enteric fever, Salmonella, Antibiotic sensitivity, Blood culture, MDR, XDR, Azithromycin, Meropenem." | 4.31 | Frequency and Antibiotics Sensitivity Pattern of Culture-Positive Salmonella Typhi in Children. ( Ahmad, M; Shah, N; Siddiqui, MA, 2023) |
| "Recently, the cefixime-ofloxacin combination is approved by Drug Controller General of India to treat typhoid fever." | 3.85 | In vitro efficacy and in silico analysis of cefixime-ofloxacin combination for Salmonella Typhi from bloodstream infection. ( Babu, P; Bakthavatchalam, YD; Doss, CGP; Kumar, DT; Munusamy, E; Ravi, R; Shankar, BA; Tayubi, IA; Thukkaram, B; Veeraraghavan, B, 2017) |
| " However, cefixime has been shown to be clinically effective against typhoid fever." | 3.71 | Mechanism of therapeutic effectiveness of cefixime against typhoid fever. ( Ikeda, F; Ikemoto, A; Matsumoto, K; Matsumoto, Y; Tawara, S; Wakai, Y, 2001) |
| "Multi-drug resistant Typhoid fever (resistant to previously used chloramphenicol, ampicillin, amoxicillin, and trimethoprim-sulfamethoxazole) has been commonly described in the South East Asia region and a recent report suggests that the salmonella typhi have reduced response to fluoroquinolones (nalidixic acid-resistant)." | 3.01 | Open Label Randomized Controlled Comparison of Three Alternative Regimes of Ciprofloxacin, Azithromycin and Cefixime for Treatment of Uncomplicated Typhoid Fever in Bangladesh. ( Ahmed, SM; Amin, MR; Das, SK; Hasan, MJ; Islam, MR; Kabir, A, 2021) |
| "Typhoid and paratyphoid (enteric fever) are febrile bacterial illnesses common in many low- and middle-income countries." | 2.82 | Treatment of enteric fever (typhoid and paratyphoid fever) with cephalosporins. ( Basnyat, B; Darton, TC; Eyre, D; Kuehn, R; Parry, CM; Stoesser, N, 2022) |
| "Cefixime (7." | 2.68 | Comparison of the efficacy, safety and cost of cefixime, ceftriaxone and aztreonam in the treatment of multidrug-resistant Salmonella typhi septicemia in children. ( Farid, Z; Girgis, NI; Hammad, O; Sultan, Y, 1995) |
| "In 9 cases the typhoidal organisms isolated were susceptible to first-line drugs." | 2.67 | Therapy of multidrug-resistant typhoid fever with oral cefixime vs. intravenous ceftriaxone. ( Bhutta, ZA; Khan, IA; Molla, AM, 1994) |
| "Cefixime proved to be an effective oral drug in this open treatment trial and was associated with minimal side effects." | 1.29 | Cefixime in the treatment of enteric fever in children. ( Farid, Z; Girgis, NI; Kilpatrick, ME; Podgore, JK; Sultan, Y, 1993) |
| "Cefixime was well-tolerated with only mild side-effects, including nausea/vomiting (8 per cent) and abdominal cramping with loose stools (6 per cent), which may have been secondary to typhoid fever." | 1.29 | Short course chemotherapy with cefixime in children with multidrug-resistant Salmonella typhi Septicaemia. ( Farid, Z; Girgis, NI; Sultan, Y; Tribble, DR, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 10 (40.00) | 18.2507 |
| 2000's | 7 (28.00) | 29.6817 |
| 2010's | 3 (12.00) | 24.3611 |
| 2020's | 5 (20.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fazaludeen Koya, S | 1 |
| Hasan Farooqui, H | 1 |
| Mehta, A | 2 |
| Selvaraj, S | 1 |
| Galea, S | 1 |
| Kuehn, R | 3 |
| Stoesser, N | 3 |
| Eyre, D | 3 |
| Darton, TC | 3 |
| Basnyat, B | 4 |
| Parry, CM | 4 |
| Ahmad, M | 1 |
| Shah, N | 1 |
| Siddiqui, MA | 1 |
| Pokharel, S | 1 |
| Karki, M | 1 |
| Acharya, B | 1 |
| Marasini, B | 1 |
| Arjyal, A | 2 |
| Amin, MR | 1 |
| Das, SK | 1 |
| Kabir, A | 1 |
| Islam, MR | 1 |
| Ahmed, SM | 1 |
| Hasan, MJ | 1 |
| Bakthavatchalam, YD | 1 |
| Kumar, DT | 1 |
| Tayubi, IA | 1 |
| Shankar, BA | 1 |
| Babu, P | 1 |
| Munusamy, E | 1 |
| Thukkaram, B | 1 |
| Ravi, R | 1 |
| Doss, CGP | 1 |
| Veeraraghavan, B | 1 |
| Tiwaskar, M | 1 |
| Begum, B | 1 |
| Haque, MA | 1 |
| Ahmed, MS | 1 |
| Islam, MN | 1 |
| Ahsan, MM | 1 |
| Khan, AH | 1 |
| Hasan, MM | 1 |
| Akhtaruzzaman, M | 1 |
| Hossain, MA | 1 |
| Khaleque, MA | 1 |
| Choudhury, AM | 1 |
| Khatun, AA | 1 |
| Martinez-Roig, A | 1 |
| Bonet-Alcaina, M | 1 |
| Casellas-Montagut, M | 1 |
| Ymbert-Pellejà, L | 1 |
| Kadhiravan, T | 1 |
| Wig, N | 1 |
| Kapil, A | 1 |
| Kabra, SK | 1 |
| Renuka, K | 1 |
| Misra, A | 1 |
| Pandit, A | 1 |
| Day, JN | 1 |
| Paudyal, B | 1 |
| Dangol, S | 1 |
| Zimmerman, MD | 1 |
| Yadav, B | 1 |
| Stepniewska, K | 1 |
| Campbell, JI | 1 |
| Dolecek, C | 1 |
| Farrar, JJ | 1 |
| Shakur, MS | 1 |
| Arzuman, SA | 1 |
| Hossain, J | 1 |
| Mehdi, H | 1 |
| Ahmed, M | 1 |
| Girgis, NI | 3 |
| Sultan, Y | 3 |
| Hammad, O | 1 |
| Farid, Z | 3 |
| Bhutta, ZA | 2 |
| Khan, IA | 1 |
| Molla, AM | 1 |
| Kilpatrick, ME | 1 |
| Podgore, JK | 1 |
| Tribble, DR | 1 |
| Rastegar Lari, A | 1 |
| Validi, N | 1 |
| Ghaffarzadeh, K | 1 |
| Shamshiri, AR | 1 |
| Memon, IA | 1 |
| Billoo, AG | 1 |
| Memon, HI | 1 |
| Mansoorali, N | 1 |
| Hussain, R | 1 |
| Malik, MS | 2 |
| Iqbal, I | 2 |
| Rabbani, W | 1 |
| Rabbani, MW | 1 |
| Cao, XT | 1 |
| Kneen, R | 1 |
| Nguyen, TA | 1 |
| Truong, DL | 1 |
| White, NJ | 1 |
| Medina Santillán, R | 1 |
| Reyes García, G | 1 |
| Herrera Benavente, I | 1 |
| Mateos García, E | 1 |
| Matsumoto, Y | 1 |
| Ikemoto, A | 1 |
| Wakai, Y | 1 |
| Ikeda, F | 1 |
| Tawara, S | 1 |
| Matsumoto, K | 1 |
| Rodrigues, C | 1 |
| Joshi, VR | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Parallel Group, Double Blinded, 1:1, Randomized Controlled Phase III Trial of Co-trimoxazole Versus Azithromycin for the Treatment of Undifferentiated Fever In Nepal[NCT02773407] | Phase 3 | 330 participants (Actual) | Interventional | 2016-05-23 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for cefixime and Typhoid Fever
| Article | Year |
|---|---|
Treatment of enteric fever (typhoid and paratyphoid fever) with cephalosporins.
Topics: Adolescent; Adult; Anti-Bacterial Agents; Anti-Infective Agents; Azithromycin; Cefixime; Ceftriaxone | 2022 |
Treatment of enteric fever (typhoid and paratyphoid fever) with cephalosporins.
Topics: Adolescent; Adult; Anti-Bacterial Agents; Anti-Infective Agents; Azithromycin; Cefixime; Ceftriaxone | 2022 |
Treatment of enteric fever (typhoid and paratyphoid fever) with cephalosporins.
Topics: Adolescent; Adult; Anti-Bacterial Agents; Anti-Infective Agents; Azithromycin; Cefixime; Ceftriaxone | 2022 |
Treatment of enteric fever (typhoid and paratyphoid fever) with cephalosporins.
Topics: Adolescent; Adult; Anti-Bacterial Agents; Anti-Infective Agents; Azithromycin; Cefixime; Ceftriaxone | 2022 |
Treatment of enteric fever (typhoid and paratyphoid fever) with cephalosporins.
Topics: Adolescent; Adult; Anti-Bacterial Agents; Anti-Infective Agents; Azithromycin; Cefixime; Ceftriaxone | 2022 |
Treatment of enteric fever (typhoid and paratyphoid fever) with cephalosporins.
Topics: Adolescent; Adult; Anti-Bacterial Agents; Anti-Infective Agents; Azithromycin; Cefixime; Ceftriaxone | 2022 |
Treatment of enteric fever (typhoid and paratyphoid fever) with cephalosporins.
Topics: Adolescent; Adult; Anti-Bacterial Agents; Anti-Infective Agents; Azithromycin; Cefixime; Ceftriaxone | 2022 |
Treatment of enteric fever (typhoid and paratyphoid fever) with cephalosporins.
Topics: Adolescent; Adult; Anti-Bacterial Agents; Anti-Infective Agents; Azithromycin; Cefixime; Ceftriaxone | 2022 |
Treatment of enteric fever (typhoid and paratyphoid fever) with cephalosporins.
Topics: Adolescent; Adult; Anti-Bacterial Agents; Anti-Infective Agents; Azithromycin; Cefixime; Ceftriaxone | 2022 |
12 trials available for cefixime and Typhoid Fever
| Article | Year |
|---|---|
Open Label Randomized Controlled Comparison of Three Alternative Regimes of Ciprofloxacin, Azithromycin and Cefixime for Treatment of Uncomplicated Typhoid Fever in Bangladesh.
Topics: Adult; Anti-Bacterial Agents; Azithromycin; Bangladesh; Cefixime; Ciprofloxacin; Humans; Microbial S | 2021 |
Comparison between azithromycin and cefixime in the treatment of typhoid fever in children.
Topics: Anti-Bacterial Agents; Azithromycin; Cefixime; Child; Child, Preschool; Female; Humans; Male; Typhoi | 2014 |
An open randomized comparison of gatifloxacin versus cefixime for the treatment of uncomplicated enteric fever.
Topics: Adolescent; Adult; Anti-Bacterial Agents; Anti-Infective Agents; Antitubercular Agents; Cefixime; Ch | 2007 |
Cefpodoxime proxetil compared with cefixime for treatment of typhoid fever in children.
Topics: Anti-Bacterial Agents; Cefixime; Cefpodoxime Proxetil; Ceftizoxime; Child; Child, Preschool; Double- | 2007 |
Comparison of the efficacy, safety and cost of cefixime, ceftriaxone and aztreonam in the treatment of multidrug-resistant Salmonella typhi septicemia in children.
Topics: Adolescent; Anti-Bacterial Agents; Aztreonam; Bacteremia; Cefixime; Cefotaxime; Ceftriaxone; Cephalo | 1995 |
Therapy of multidrug-resistant typhoid fever with oral cefixime vs. intravenous ceftriaxone.
Topics: Administration, Oral; Adolescent; Anti-Bacterial Agents; Cefixime; Cefotaxime; Ceftriaxone; Child, P | 1994 |
Cefixime: an oral option for the treatment of multidrug-resistant enteric fever in children.
Topics: Administration, Oral; Anti-Bacterial Agents; Cefixime; Cefotaxime; Cephalosporins; Child; Child, Pre | 1997 |
Plasma cytokines in paediatric typhoidal salmonellosis: correlation with clinical course and outcome.
Topics: Adolescent; Cefixime; Cefotaxime; Ceftriaxone; Cephalosporins; Child; Child, Preschool; Cohort Studi | 1997 |
A comparative study of cefixime and chloramphenicol in children with typhoid fever.
Topics: Anti-Bacterial Agents; Cefixime; Cefotaxime; Cephalosporins; Child; Child, Preschool; Chloramphenico | 1998 |
A comparative study of cefixime and chloramphenicol in children with typhoid fever.
Topics: Anti-Bacterial Agents; Cefixime; Cefotaxime; Cephalosporins; Child; Child, Preschool; Chloramphenico | 1998 |
A comparative study of ofloxacin and cefixime for treatment of typhoid fever in children. The Dong Nai Pediatric Center Typhoid Study Group.
Topics: Adolescent; Anti-Infective Agents; Cefixime; Cefotaxime; Cephalosporins; Child; Child, Preschool; Dr | 1999 |
Efficacy of cefixime in the therapy of typhoid fever.
Topics: Adolescent; Adult; Anti-Bacterial Agents; Cefixime; Cephalosporins; Child; Child, Preschool; Feces; | 2000 |
12 other studies available for cefixime and Typhoid Fever
| Article | Year |
|---|---|
Quantifying antibiotic use in typhoid fever in India: a cross-sectional analysis of private sector medical audit data, 2013-2015.
Topics: Anti-Bacterial Agents; Cefixime; Cephalosporins; Child; Cross-Sectional Studies; Drug Prescriptions; | 2022 |
Frequency and Antibiotics Sensitivity Pattern of Culture-Positive Salmonella Typhi in Children.
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Azithromycin; Cefixime; Ceftriaxone; Child; Chloramphe | 2023 |
Outbreak of acute undifferentiated febrile illness in Kathmandu, Nepal: clinical and epidemiological investigation.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Azithromycin; Cefixime; Child; Di | 2020 |
In vitro efficacy and in silico analysis of cefixime-ofloxacin combination for Salmonella Typhi from bloodstream infection.
Topics: Anti-Bacterial Agents; Bacteremia; Cefixime; Humans; India; Microbial Sensitivity Tests; Ofloxacin; | 2017 |
Cefixime-ofloxacin Combination in the Management of Uncomplicated Typhoid Fever in the Indian Community Setting.
Topics: Anti-Bacterial Agents; Cefixime; Drug Combinations; Humans; India; Ofloxacin; Salmonella typhi; Typh | 2019 |
Pancreatitis in typhoid fever relapse.
Topics: Anti-Bacterial Agents; Cefixime; Child; Humans; Male; Pancreatitis; Recurrence; Salmonella typhi; Ty | 2009 |
Clinical outcomes in typhoid fever: adverse impact of infection with nalidixic acid-resistant Salmonella typhi.
Topics: Adolescent; Adult; Anti-Bacterial Agents; Cefixime; Child; Child, Preschool; Ciprofloxacin; Drug Res | 2005 |
Cefixime in the treatment of enteric fever in children.
Topics: Adolescent; Anti-Bacterial Agents; Cefixime; Cefotaxime; Child; Child, Preschool; Drug Resistance, M | 1993 |
Short course chemotherapy with cefixime in children with multidrug-resistant Salmonella typhi Septicaemia.
Topics: Adolescent; Anti-Bacterial Agents; Cefixime; Cefotaxime; Child; Child, Preschool; Drug Resistance, M | 1995 |
In vitro activity of cefixime versus ceftizoxime against Salmonella typhi.
Topics: Anti-Bacterial Agents; Cefixime; Cefotaxime; Ceftizoxime; Cephalosporins; Drug Resistance, Microbial | 1997 |
Mechanism of therapeutic effectiveness of cefixime against typhoid fever.
Topics: Animals; Cefixime; Cell Survival; Cephalosporins; Disease Models, Animal; Humans; Male; Mice; Mice, | 2001 |
Salmonella typhiin the past decade: learning to live with resistance.
Topics: Amoxicillin; Anti-Bacterial Agents; Cefixime; Ceftriaxone; Drug Resistance, Bacterial; Drug Resistan | 2002 |