cefixime has been researched along with Pyelonephritis in 9 studies
Cefixime: A third-generation cephalosporin antibiotic that is stable to hydrolysis by beta-lactamases.
cefixime : A third-generation cephalosporin antibiotic bearing vinyl and (2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-[(carboxymethoxy)imino]acetamido groups at positions 3 and 7, respectively, of the cephem skeleton. It is used in the treatment of gonorrhoea, tonsilitis, pharyngitis, bronchitis, and urinary tract infections.
Pyelonephritis: Inflammation of the KIDNEY involving the renal parenchyma (the NEPHRONS); KIDNEY PELVIS; and KIDNEY CALICES. It is characterized by ABDOMINAL PAIN; FEVER; NAUSEA; VOMITING; and occasionally DIARRHEA.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In a prospective, open clinical study, 50 urological patients with acute pyelonephritis were treated with the oral cephalosporin cefixime." | 9.06 | [Effectiveness and tolerance of cefixime in the treatment of acute pyelonephritis]. ( Segal, A; Tröster, K; Weissbach, L, 1990) |
| "Cefixime seems to be an acceptable alternative to the regimens containing an aminopenicillin and an aminoglycoside for the treatment of community-acquired non-complicated APN." | 6.69 | [Cefixime versus amoxicillin plus netilmicin in the treatment of community-acquired non-complicated acute pyelonephritis]. ( Almela, M; García San Miguel, J; Marco, F; Martínez, JA; Mensa, J; Moreno-Martínez, A; Soriano, E; Vila, J, 1998) |
| "To compare the short-term effectiveness of ceftriaxone single dose followed by cefixime with a standard treatment of acute uncomplicated pyelonephritis in women." | 5.10 | Short-term effectiveness of ceftriaxone single dose in the initial treatment of acute uncomplicated pyelonephritis in women. A randomised controlled trial. ( Collvinent, B; Horcajada, JP; Marco, F; Mensa, J; Millá, J; Miró, O; Moreno, A; Sanchez, M, 2002) |
| "In a prospective, open clinical study, 50 urological patients with acute pyelonephritis were treated with the oral cephalosporin cefixime." | 5.06 | [Effectiveness and tolerance of cefixime in the treatment of acute pyelonephritis]. ( Segal, A; Tröster, K; Weissbach, L, 1990) |
| "Cefixime seems to be an acceptable alternative to the regimens containing an aminopenicillin and an aminoglycoside for the treatment of community-acquired non-complicated APN." | 2.69 | [Cefixime versus amoxicillin plus netilmicin in the treatment of community-acquired non-complicated acute pyelonephritis]. ( Almela, M; García San Miguel, J; Marco, F; Martínez, JA; Mensa, J; Moreno-Martínez, A; Soriano, E; Vila, J, 1998) |
| "Cefixime was the commonly prescribed antimicrobial (p = 0." | 1.48 | Antimicrobial misuse in pediatric urinary tract infections: recurrences and renal scarring. ( Jayaweera, JAAS; Reyes, M, 2018) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (33.33) | 18.2507 |
| 2000's | 2 (22.22) | 29.6817 |
| 2010's | 4 (44.44) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Jayaweera, JAAS | 1 |
| Reyes, M | 1 |
| Finnell, SM | 1 |
| Carroll, AE | 1 |
| Downs, SM | 1 |
| Bocquet, N | 1 |
| Sergent Alaoui, A | 1 |
| Jais, JP | 1 |
| Gajdos, V | 1 |
| Guigonis, V | 1 |
| Lacour, B | 1 |
| Chéron, G | 1 |
| de La Vaissière, B | 1 |
| Castello, B | 1 |
| Quinet, B | 1 |
| Cohen, R | 1 |
| Grimprel, E | 1 |
| Moreno-Martínez, A | 1 |
| Mensa, J | 2 |
| Martínez, JA | 1 |
| Marco, F | 2 |
| Vila, J | 1 |
| Almela, M | 1 |
| García San Miguel, J | 1 |
| Soriano, E | 1 |
| Hoberman, A | 1 |
| Wald, ER | 1 |
| Hickey, RW | 1 |
| Baskin, M | 1 |
| Charron, M | 1 |
| Majd, M | 1 |
| Kearney, DH | 1 |
| Reynolds, EA | 1 |
| Ruley, J | 1 |
| Janosky, JE | 1 |
| Sanchez, M | 1 |
| Collvinent, B | 1 |
| Miró, O | 1 |
| Horcajada, JP | 1 |
| Moreno, A | 1 |
| Millá, J | 1 |
| Weissbach, L | 1 |
| Segal, A | 1 |
| Tröster, K | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The Effect of Bladder Stimulation Technique on Urine Specimen Collection in Newborns: A Randomized Controlled Study[NCT05416736] | 64 participants (Actual) | Interventional | 2021-10-15 | Completed | |||
| Treatment of Acute Pyelonephritis With Gram Negative Strains in Infants and Children Less Than 3 Years Old. Cefixime PO 10d vs Ceftriaxone IV 4d Followed by Cefixime PO 6d. Multicenter, Randomised Trial of Equivalence.[NCT00136656] | Phase 4 | 700 participants (Actual) | Interventional | 2005-07-31 | Completed | ||
| Evaluation of the Effectiveness of Antibiotic Prophylaxis in Children With a History of Upper Urinary Tract Infections:a Multicentre Randomised Study[NCT00156546] | Phase 4 | 660 participants | Interventional | 2000-05-31 | Active, not recruiting | ||
| A Multicenter Randomized Controlled Trial of Antibiotic Treatment in Children With Urinary Tract Infections: Oral Amoxicillin/Clavulanic Acid vs Initial iv Ceftriaxone.[NCT00161330] | Phase 3 | 440 participants | Interventional | 2000-06-30 | Terminated | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for cefixime and Pyelonephritis
| Article | Year |
|---|---|
Acute pyelonephritis in children: antibiotic therapy depending on the clinical context.
Topics: Acute Disease; Anti-Bacterial Agents; Cefixime; Ceftriaxone; Child; Child, Preschool; Humans; Microb | 2010 |
Technical report—Diagnosis and management of an initial UTI in febrile infants and young children.
Topics: Antibiotic Prophylaxis; Cefixime; Fever; Humans; Infant; Prevalence; Pyelonephritis; Radiography; Re | 2011 |
5 trials available for cefixime and Pyelonephritis
| Article | Year |
|---|---|
Randomized trial of oral versus sequential IV/oral antibiotic for acute pyelonephritis in children.
Topics: Acute Disease; Administration, Oral; Anti-Bacterial Agents; Calcitonin; Calcitonin Gene-Related Pept | 2012 |
[Cefixime versus amoxicillin plus netilmicin in the treatment of community-acquired non-complicated acute pyelonephritis].
Topics: Acute Disease; Adult; Aged; Amoxicillin; Bacteremia; Cefixime; Cefotaxime; Cephalosporins; Communica | 1998 |
Oral versus initial intravenous therapy for urinary tract infections in young febrile children.
Topics: Acute Disease; Administration, Oral; Cefixime; Cefotaxime; Cephalosporins; Cost-Benefit Analysis; Fe | 1999 |
Oral versus initial intravenous therapy for urinary tract infections in young febrile children.
Topics: Acute Disease; Administration, Oral; Cefixime; Cefotaxime; Cephalosporins; Cost-Benefit Analysis; Fe | 1999 |
Oral versus initial intravenous therapy for urinary tract infections in young febrile children.
Topics: Acute Disease; Administration, Oral; Cefixime; Cefotaxime; Cephalosporins; Cost-Benefit Analysis; Fe | 1999 |
Oral versus initial intravenous therapy for urinary tract infections in young febrile children.
Topics: Acute Disease; Administration, Oral; Cefixime; Cefotaxime; Cephalosporins; Cost-Benefit Analysis; Fe | 1999 |
Short-term effectiveness of ceftriaxone single dose in the initial treatment of acute uncomplicated pyelonephritis in women. A randomised controlled trial.
Topics: Acute Disease; Adult; Cefixime; Ceftriaxone; Cephalosporins; Female; Humans; Middle Aged; Prospectiv | 2002 |
[Effectiveness and tolerance of cefixime in the treatment of acute pyelonephritis].
Topics: Acute Disease; Adult; Aged; Aged, 80 and over; Anti-Infective Agents, Urinary; Body Temperature; Cef | 1990 |
2 other studies available for cefixime and Pyelonephritis
| Article | Year |
|---|---|
Antimicrobial misuse in pediatric urinary tract infections: recurrences and renal scarring.
Topics: Anti-Bacterial Agents; Biofilms; Cefixime; Child; Child, Preschool; Cicatrix; Escherichia coli; Esch | 2018 |
[Management of acute pyelonephritis in patients older than 3 months: survey conducted in 39 paediatric emergency departments of the Ile de France Region in 2004].
Topics: Acute Disease; Administration, Oral; Adolescent; Age Factors; Anti-Bacterial Agents; Cefaclor; Cefix | 2006 |