cefixime has been researched along with Otitis Media in 35 studies
Cefixime: A third-generation cephalosporin antibiotic that is stable to hydrolysis by beta-lactamases.
cefixime : A third-generation cephalosporin antibiotic bearing vinyl and (2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-[(carboxymethoxy)imino]acetamido groups at positions 3 and 7, respectively, of the cephem skeleton. It is used in the treatment of gonorrhoea, tonsilitis, pharyngitis, bronchitis, and urinary tract infections.
Otitis Media: Inflammation of the MIDDLE EAR including the AUDITORY OSSICLES and the EUSTACHIAN TUBE.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A multicentre, open-label, randomized study was performed in 501 out-patients with acute otitis media, aged 6-36 months, to study the impact of treatment with either cefixime suspension 8 mg/kg/day bd or co-amoxiclav suspension 80 mg/kg/day tds for 10 days on nasopharyngeal carriage of Streptococcus pneumoniae and Haemophilus influenzae." | 9.08 | Effects of cefixime or co-amoxiclav treatment on nasopharyngeal carriage of Streptococcus pneumoniae and Haemophilus influenzae in children with acute otitis media. ( Bégué, P; Boulesteix, J; Dabernat, H; de La Roque, F; Dubreuil, C; Geslin, P; Megraud, F; Scheimberg, A; Trinh, A, 1998) |
| "To compare the efficacy of cefixime with amoxicillin in the treatment of acute otitis media in children." | 9.07 | Efficacy of cefixime in the treatment of acute otitis media in children. ( Anwar, R; Bannister, ER; Howie, VM; Nguyen, HK; Owen, MJ; Swank, PR, 1993) |
| " The aim of this study was to compare the clinical efficacy of cefixime with that of amoxicillin in the treatment of acute otitis media in 40 children." | 9.07 | Cefixime vs amoxicillin in the treatment of acute otitis media in infants and children. ( Marchisio, P; Principi, N, 1991) |
| "A large scale multicentre clinical study was undertaken to assess the efficacy and tolerability of cefixime in the treatment of acute otitis media in children." | 9.07 | Efficacy and tolerability of cefixime in otitis media. A multicentre study in over 25,000 children. ( Wu, DH, 1991) |
| "Cefixime was compared with amoxicillin for treatment of acute otitis media in a randomized trial." | 9.07 | Cefixime compared with amoxicillin for treatment of acute otitis media. ( Carlin, SA; Christopher, NC; Johnson, CE; Rehmus, JM; Roberts, DG; Shurin, PA; Super, DM; Whitwell, JK, 1991) |
| "A total of 325 eligible paediatric patients were entered into an open, randomised, multicentre general practice study to assess the comparative efficacy of a new third-generation oral cephalosporin, cefixime, with respect to that of amoxycillin in the treatment of acute otitis media." | 9.06 | A general practice comparative study of a new third-generation oral cephalosporin, cefixime, with amoxycillin in the treatment of acute paediatric otitis media. ( Leigh, AP; Millar, ED; Robinson, D, 1989) |
| "A double blind study was carried out to compare the efficacy and safety of cefixime (CFIX), a new oral cephem with cefaclor (CCL) in the treatment of 245 children weighing 10 approximately 30 kg, with acute suppurative otitis media." | 9.06 | [A parallel comparative double blind study of cefixime with cefaclor in the treatment of acute suppurative otitis media in children]. ( Baba, S; Itoh, Y; Kawamura, S; Kinoshita, H; Kobayashi, K; Mori, Y; Onishi, S; Shimada, J; Suzuki, K; Ueda, R, 1987) |
| "Amoxicillin-clavulanate was administered at 40 mg/kg/day in three divided doses (t." | 7.77 | Multi-investigator evaluation of the efficacy and safety of cefprozil, amoxicillin-clavulanate, cefixime and cefaclor in the treatment of acute otitis media. ( Kafetzis, DA, 1994) |
| "0001), and the adverse experience rate was lower (P = 0." | 6.68 | Comparison of the efficacy, safety and acceptability of cefixime and amoxicillin/clavulanate in acute otitis media. ( Gooch, WM; Philips, A; Rhoades, R; Rosenberg, R; Schaten, R; Starobin, S, 1997) |
| "Cefixime was administered for five to twelve days twice daily in a dose of 200 mg." | 6.67 | [Cefixime treatment in different bacterial infections in the ENT region]. ( Benner, U; Blessing, R; Pelz, K; Schlenter, WW, 1990) |
| "Cefixime is a viable alternative to amoxicillin for infants and children with acute otitis media when: (1) a beta-lactamase-producing H." | 6.38 | Review of cefixime in the treatment of otitis media in infants and children. ( Bluestone, CD, 1993) |
| "Previous studies using the chinchilla animal model demonstrated that the third generation cephalosporin cefixime (Suprax) with split dosing was as effective as ampicillin in sterilizing the middle ear cleft when infected with S." | 5.29 | An experimental study of cefixime in the treatment of Streptococcus pneumoniae otitis media. ( Dolitsky, JN; Doyle, WJ; Magit, AE; Rosenfeld, RM; Seroky, JT; Swarts, JD, 1994) |
| "A multicentre, open-label, randomized study was performed in 501 out-patients with acute otitis media, aged 6-36 months, to study the impact of treatment with either cefixime suspension 8 mg/kg/day bd or co-amoxiclav suspension 80 mg/kg/day tds for 10 days on nasopharyngeal carriage of Streptococcus pneumoniae and Haemophilus influenzae." | 5.08 | Effects of cefixime or co-amoxiclav treatment on nasopharyngeal carriage of Streptococcus pneumoniae and Haemophilus influenzae in children with acute otitis media. ( Bégué, P; Boulesteix, J; Dabernat, H; de La Roque, F; Dubreuil, C; Geslin, P; Megraud, F; Scheimberg, A; Trinh, A, 1998) |
| "To compare the efficacy of cefixime with amoxicillin in the treatment of acute otitis media in children." | 5.07 | Efficacy of cefixime in the treatment of acute otitis media in children. ( Anwar, R; Bannister, ER; Howie, VM; Nguyen, HK; Owen, MJ; Swank, PR, 1993) |
| " The aim of this study was to compare the clinical efficacy of cefixime with that of amoxicillin in the treatment of acute otitis media in 40 children." | 5.07 | Cefixime vs amoxicillin in the treatment of acute otitis media in infants and children. ( Marchisio, P; Principi, N, 1991) |
| "A large scale multicentre clinical study was undertaken to assess the efficacy and tolerability of cefixime in the treatment of acute otitis media in children." | 5.07 | Efficacy and tolerability of cefixime in otitis media. A multicentre study in over 25,000 children. ( Wu, DH, 1991) |
| "Cefixime was compared with amoxicillin for treatment of acute otitis media in a randomized trial." | 5.07 | Cefixime compared with amoxicillin for treatment of acute otitis media. ( Carlin, SA; Christopher, NC; Johnson, CE; Rehmus, JM; Roberts, DG; Shurin, PA; Super, DM; Whitwell, JK, 1991) |
| "Cefixime was used in the treatment of 59 patients, 44 of whom had sinusitis, 9 otitis media and 6 various ENT infections." | 5.06 | [Efficacy and tolerability of cefixime in the treatment of otorhinolaryngeal infections in adults]. ( Bossard, B; Gehanno, P; Peynègre, R, 1989) |
| "A total of 325 eligible paediatric patients were entered into an open, randomised, multicentre general practice study to assess the comparative efficacy of a new third-generation oral cephalosporin, cefixime, with respect to that of amoxycillin in the treatment of acute otitis media." | 5.06 | A general practice comparative study of a new third-generation oral cephalosporin, cefixime, with amoxycillin in the treatment of acute paediatric otitis media. ( Leigh, AP; Millar, ED; Robinson, D, 1989) |
| "A double blind study was carried out to compare the efficacy and safety of cefixime (CFIX), a new oral cephem with cefaclor (CCL) in the treatment of 245 children weighing 10 approximately 30 kg, with acute suppurative otitis media." | 5.06 | [A parallel comparative double blind study of cefixime with cefaclor in the treatment of acute suppurative otitis media in children]. ( Baba, S; Itoh, Y; Kawamura, S; Kinoshita, H; Kobayashi, K; Mori, Y; Onishi, S; Shimada, J; Suzuki, K; Ueda, R, 1987) |
| "Amoxicillin-clavulanate was administered at 40 mg/kg/day in three divided doses (t." | 3.77 | Multi-investigator evaluation of the efficacy and safety of cefprozil, amoxicillin-clavulanate, cefixime and cefaclor in the treatment of acute otitis media. ( Kafetzis, DA, 1994) |
| " Using the chinchilla animal model, we compared the efficacy of ceftibuten (n = 33) with that of saline (n = 34), ampicillin (n = 32), and cefixime (n = 31) for the treatment of acute otitis media caused by beta-lactamase-producing nontypeable Hemophilus influenzae." | 3.68 | Efficacy of ceftibuten for acute otitis media caused by Hemophilus influenzae: an animal study. ( Doyle, WJ; Greene, I; Rosenfeld, RM; Seroky, J; Swarts, JD, 1993) |
| "In a pilot study with a limited number of patients the efficacy and tolerance of cefixime, a new oral cephalosporin antibiotic, were investigated in 15 children with the clinical diagnosis of bacterial respiratory tract infection, otitis media or urinary tract infection." | 3.68 | [Therapy of pediatric infections with cefixime]. ( Helwig, H, 1990) |
| "A clinical study of cefixime (CFIX), a new oral cephalosporin, was carried out to evaluate its therapeutic effectiveness on bacterial infections in children." | 3.67 | [Clinical studies on cefixime in pediatrics]. ( Endo, S; Hosoda, T; Masuda, M; Mimoto, H; Miyao, M; Tanaka, H; Yuasa, Y, 1986) |
| "Cefixime was not more effective than topical polymyxin-bacitracin in either the eradication of conjunctival colonization with respiratory pathogens or the prevention of AOM in children with acute bacterial conjunctivitis." | 2.70 | Short term oral cefixime therapy for treatment of bacterial conjunctivitis. ( Greenberg, D; Hoberman, A; Wald, ER, 2001) |
| "0001), and the adverse experience rate was lower (P = 0." | 2.68 | Comparison of the efficacy, safety and acceptability of cefixime and amoxicillin/clavulanate in acute otitis media. ( Gooch, WM; Philips, A; Rhoades, R; Rosenberg, R; Schaten, R; Starobin, S, 1997) |
| "Cefixime was administered for five to twelve days twice daily in a dose of 200 mg." | 2.67 | [Cefixime treatment in different bacterial infections in the ENT region]. ( Benner, U; Blessing, R; Pelz, K; Schlenter, WW, 1990) |
| "Cefixime is a viable alternative to amoxicillin for infants and children with acute otitis media when: (1) a beta-lactamase-producing H." | 2.38 | Review of cefixime in the treatment of otitis media in infants and children. ( Bluestone, CD, 1993) |
| "Previous studies using the chinchilla animal model demonstrated that the third generation cephalosporin cefixime (Suprax) with split dosing was as effective as ampicillin in sterilizing the middle ear cleft when infected with S." | 1.29 | An experimental study of cefixime in the treatment of Streptococcus pneumoniae otitis media. ( Dolitsky, JN; Doyle, WJ; Magit, AE; Rosenfeld, RM; Seroky, JT; Swarts, JD, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (17.14) | 18.7374 |
| 1990's | 28 (80.00) | 18.2507 |
| 2000's | 1 (2.86) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Principi, N | 2 |
| Marchisio, P | 2 |
| Grasso, R | 1 |
| Filiberti, G | 1 |
| Blatto, M | 1 |
| Tomiyama, M | 1 |
| Kafetzis, DA | 1 |
| Magit, AE | 1 |
| Dolitsky, JN | 1 |
| Doyle, WJ | 2 |
| Swarts, JD | 2 |
| Seroky, JT | 1 |
| Rosenfeld, RM | 2 |
| Hefelfinger, DC | 1 |
| Berman, S | 1 |
| Roark, R | 1 |
| Bluestone, CD | 1 |
| Owen, MJ | 1 |
| Anwar, R | 1 |
| Nguyen, HK | 1 |
| Swank, PR | 1 |
| Bannister, ER | 1 |
| Howie, VM | 1 |
| Seroky, J | 1 |
| Greene, I | 1 |
| Boulesteix, J | 2 |
| Bégué, P | 2 |
| Dubreuil, C | 2 |
| Mégraud, F | 2 |
| Dabernat, H | 2 |
| Geslin, P | 2 |
| de La Rocque, F | 1 |
| Trinh, A | 2 |
| Liston, TE | 1 |
| Gooch, WM | 1 |
| Philips, A | 1 |
| Rhoades, R | 1 |
| Rosenberg, R | 1 |
| Schaten, R | 1 |
| Starobin, S | 1 |
| de La Roque, F | 1 |
| Scheimberg, A | 1 |
| de Lalla, F | 1 |
| Ludwig, E | 1 |
| Ogle, JW | 1 |
| Wald, ER | 1 |
| Greenberg, D | 1 |
| Hoberman, A | 1 |
| Wu, DH | 1 |
| Marchant, CD | 1 |
| Carlin, SA | 2 |
| Johnson, CE | 2 |
| Shurin, PA | 2 |
| Del Beccaro, MA | 1 |
| Mendelman, PM | 1 |
| Inglis, AF | 1 |
| Richardson, MA | 1 |
| Duncan, NO | 1 |
| Clausen, CR | 1 |
| Stull, TL | 1 |
| Di Nola, F | 1 |
| Arione, R | 1 |
| Bramato, C | 1 |
| Charles, D | 1 |
| Bluestone, MD | 1 |
| Ottolini, MG | 1 |
| Ascher, DP | 1 |
| Cieslak, TJ | 1 |
| Modica-Lucero, S | 1 |
| Super, DM | 1 |
| Rehmus, JM | 1 |
| Roberts, DG | 1 |
| Christopher, NC | 1 |
| Whitwell, JK | 1 |
| Theopold, M | 1 |
| Benner, U | 2 |
| Bauernfeind, A | 1 |
| Schlenter, WW | 1 |
| Blessing, R | 1 |
| Pelz, K | 1 |
| Helwig, H | 1 |
| Scott, HV | 1 |
| Pannowitz, D | 1 |
| Ketelbey, JW | 1 |
| Peynègre, R | 1 |
| Bossard, B | 1 |
| Gehanno, P | 1 |
| Bodor, FF | 1 |
| Leigh, AP | 1 |
| Robinson, D | 1 |
| Millar, ED | 1 |
| Baba, S | 1 |
| Kinoshita, H | 1 |
| Mori, Y | 1 |
| Suzuki, K | 1 |
| Shimada, J | 1 |
| Kawamura, S | 1 |
| Onishi, S | 1 |
| Ueda, R | 1 |
| Kobayashi, K | 1 |
| Itoh, Y | 1 |
| Hosoda, T | 1 |
| Masuda, M | 1 |
| Miyao, M | 1 |
| Mimoto, H | 1 |
| Endo, S | 1 |
| Yuasa, Y | 1 |
| Tanaka, H | 1 |
4 reviews available for cefixime and Otitis Media
| Article | Year |
|---|---|
Multi-investigator evaluation of the efficacy and safety of cefprozil, amoxicillin-clavulanate, cefixime and cefaclor in the treatment of acute otitis media.
Topics: Acute Disease; Amoxicillin; Amoxicillin-Potassium Clavulanate Combination; Anti-Bacterial Agents; Ba | 1994 |
Review of cefixime in the treatment of otitis media in infants and children.
Topics: Animals; Anti-Bacterial Agents; Cefixime; Cefotaxime; Child; Child, Preschool; Clinical Trials as To | 1993 |
Management of otitis media. A review.
Topics: Amoxicillin; Anti-Bacterial Agents; Anti-Infective Agents; Cefaclor; Cefixime; Cefotaxime; Cefuroxim | 1995 |
[Cefixime. Microbiologic, kinetic and clinical profile].
Topics: Animals; Bacteria; Cefixime; Cefotaxime; Gonorrhea; Humans; Microbial Sensitivity Tests; Otitis Medi | 1991 |
20 trials available for cefixime and Otitis Media
| Article | Year |
|---|---|
[The effect of cefaclor and cefixime on nasopharyngeal pathogens in children].
Topics: Acute Disease; Anti-Bacterial Agents; Bacteria; Cefaclor; Cefixime; Cefotaxime; Child; Child, Presch | 1995 |
Multi-investigator evaluation of the efficacy and safety of cefprozil, amoxicillin-clavulanate, cefixime and cefaclor in the treatment of acute otitis media.
Topics: Acute Disease; Amoxicillin; Amoxicillin-Potassium Clavulanate Combination; Anti-Bacterial Agents; Ba | 1994 |
Factors influencing outcome in children treated with antibiotics for acute otitis media.
Topics: Acute Disease; Amoxicillin; Anti-Bacterial Agents; Cefaclor; Cefixime; Cefotaxime; Cephalosporins; C | 1993 |
Efficacy of cefixime in the treatment of acute otitis media in children.
Topics: Acute Disease; Administration, Oral; Amoxicillin; Anti-Infective Agents; Cefixime; Cefotaxime; Child | 1993 |
Acute otitis media in children: a study of nasopharyngeal carriage of potential pathogens and therapeutic efficacy of cefixime and amoxicillin-clavulanate.
Topics: Acute Disease; Amoxicillin; Amoxicillin-Potassium Clavulanate Combination; Bacteria; Cefixime; Cefot | 1995 |
Comparison of the efficacy, safety and acceptability of cefixime and amoxicillin/clavulanate in acute otitis media.
Topics: Acute Disease; Amoxicillin; Amoxicillin-Potassium Clavulanate Combination; Cefixime; Cefotaxime; Cep | 1997 |
Effects of cefixime or co-amoxiclav treatment on nasopharyngeal carriage of Streptococcus pneumoniae and Haemophilus influenzae in children with acute otitis media.
Topics: Amoxicillin-Potassium Clavulanate Combination; Anti-Bacterial Agents; beta-Lactam Resistance; Cefixi | 1998 |
Cefixime in the treatment of respiratory and urinary tract infections.
Topics: Adult; Cefixime; Cefotaxime; Cephalosporins; Child; Humans; Otitis Media; Pneumococcal Infections; R | 1998 |
Short term oral cefixime therapy for treatment of bacterial conjunctivitis.
Topics: Acute Disease; Administration, Oral; Administration, Topical; Anti-Bacterial Agents; Bacitracin; Cef | 2001 |
Cefixime vs amoxicillin in the treatment of acute otitis media in infants and children.
Topics: Acute Disease; Amoxicillin; Cefixime; Cefotaxime; Child; Child, Preschool; Female; Humans; Infant; I | 1991 |
Efficacy and tolerability of cefixime in otitis media. A multicentre study in over 25,000 children.
Topics: Acute Disease; Cefixime; Cefotaxime; Child; Child, Preschool; Drug Tolerance; Female; Humans; Infant | 1991 |
Measuring the comparative efficacy of antibacterial agents for acute otitis media: the "Pollyanna phenomenon".
Topics: Acute Disease; Amoxicillin; Ampicillin; Anti-Bacterial Agents; beta-Lactamase Inhibitors; Cefaclor; | 1992 |
Bacteriology of acute otitis media: a new perspective.
Topics: Acute Disease; Adolescent; Amoxicillin; Amoxicillin-Potassium Clavulanate Combination; Bacteria; Bac | 1992 |
Cefixime compared with amoxicillin for treatment of acute otitis media.
Topics: Acute Disease; Adolescent; Amoxicillin; Bacterial Infections; Cefixime; Cefotaxime; Child; Child, Pr | 1991 |
[Effectiveness and tolerance of cefixime in bacterial infections in the ENT area].
Topics: Adult; Anti-Infective Agents; Bacterial Infections; Cefixime; Cefotaxime; Drug Tolerance; Female; Hu | 1990 |
[Cefixime treatment in different bacterial infections in the ENT region].
Topics: Adolescent; Adult; Anti-Bacterial Agents; Bacterial Infections; Cefixime; Cefotaxime; Drug Tolerance | 1990 |
Cefixime: clinical trial against otitis media and tonsillitis.
Topics: Administration, Oral; Cefixime; Cefotaxime; Child; Child, Preschool; Drug Administration Schedule; D | 1990 |
[Efficacy and tolerability of cefixime in the treatment of otorhinolaryngeal infections in adults].
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Cefixime; Cefotaxime; Clinical Trials as Topic; Female; | 1989 |
A general practice comparative study of a new third-generation oral cephalosporin, cefixime, with amoxycillin in the treatment of acute paediatric otitis media.
Topics: Acute Disease; Adolescent; Amoxicillin; Cefixime; Cefotaxime; Child; Child, Preschool; Family Practi | 1989 |
[A parallel comparative double blind study of cefixime with cefaclor in the treatment of acute suppurative otitis media in children].
Topics: Acute Disease; Age Factors; Cefaclor; Cefixime; Cefotaxime; Cephalexin; Child; Child, Preschool; Cli | 1987 |
12 other studies available for cefixime and Otitis Media
| Article | Year |
|---|---|
Cefixime versus amoxicillin in the treatment of acute otitis media in infants and children.
Topics: Acute Disease; Amoxicillin; Cefixime; Child; Child, Preschool; Controlled Clinical Trials as Topic; | 1989 |
An experimental study of cefixime in the treatment of Streptococcus pneumoniae otitis media.
Topics: Acoustic Impedance Tests; Acute Disease; Ampicillin; Animals; Anti-Infective Agents; Cefixime; Cefot | 1994 |
Cefixime therapy for otitis media.
Topics: Acute Disease; Amoxicillin; Anti-Infective Agents; Cefixime; Cefotaxime; Child; Chronic Disease; Hum | 1993 |
Efficacy of ceftibuten for acute otitis media caused by Hemophilus influenzae: an animal study.
Topics: Acute Disease; Ampicillin; Animals; Anti-Bacterial Agents; Cefixime; Cefotaxime; Ceftibuten; Cephalo | 1993 |
[Infections in childhood; from respiratory infections to tropical medicine].
Topics: Anti-Bacterial Agents; Cefixime; Cefotaxime; Cephalosporins; Child; Dexamethasone; Humans; Meningiti | 1993 |
Cefixime in the treatment of upper respiratory tract infections and otitis media.
Topics: Cefixime; Cefotaxime; Cephalosporins; Humans; Otitis Media; Patient Compliance; Penicillin Resistanc | 1998 |
Antimicrobial therapy for ambulatory pediatrics.
Topics: Ambulatory Care; Anti-Bacterial Agents; Anti-Infective Agents; Cefixime; Cefuroxime; Cephalexin; Cep | 1999 |
[Epidemiology, bacteriology and clinical experience with cefixime in the treatment of acute infantile otitis media].
Topics: Acute Disease; Anti-Infective Agents; Cefixime; Cefotaxime; Child; Child, Preschool; Humans; Infant; | 1991 |
Pneumococcal bacteremia during oral treatment with cefixime for otitis media.
Topics: Administration, Oral; Cefixime; Cefotaxime; Drug Resistance, Microbial; Humans; Infant; Male; Otitis | 1991 |
[Therapy of pediatric infections with cefixime].
Topics: Anti-Infective Agents; Bronchitis; Cefixime; Cefotaxime; Child; Child, Preschool; Humans; Lymphadeni | 1990 |
Systemic antibiotics for treatment of the conjunctivitis-otitis media syndrome.
Topics: Administration, Oral; Ampicillin; Anti-Bacterial Agents; Cefaclor; Cefixime; Cefotaxime; Child; Chil | 1989 |
[Clinical studies on cefixime in pediatrics].
Topics: Bacteria; Bacterial Infections; Cefixime; Cefotaxime; Chemical and Drug Induced Liver Injury; Child; | 1986 |