cefixime has been researched along with Otitis Media with Effusion in 14 studies
Cefixime: A third-generation cephalosporin antibiotic that is stable to hydrolysis by beta-lactamases.
cefixime : A third-generation cephalosporin antibiotic bearing vinyl and (2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-[(carboxymethoxy)imino]acetamido groups at positions 3 and 7, respectively, of the cephem skeleton. It is used in the treatment of gonorrhoea, tonsilitis, pharyngitis, bronchitis, and urinary tract infections.
Otitis Media with Effusion: Inflammation of the middle ear with a clear pale yellow-colored transudate.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Cefixime, a new third generation cephalosporin antibiotic for oral use, was evaluated for safety and efficacy in the treatment of children with acute otitis media with effusion." | 9.06 | Randomized, open label, multicenter trial of cefixime compared with amoxicillin for treatment of acute otitis media with effusion. ( McLinn, SE, 1987) |
| "Cefixime, a new third generation cephalosporin antibiotic for oral use, was evaluated for safety and efficacy in the treatment of children with acute otitis media with effusion." | 5.06 | Randomized, open label, multicenter trial of cefixime compared with amoxicillin for treatment of acute otitis media with effusion. ( McLinn, SE, 1987) |
| "The ability of cefixime or amoxicillin to eradicate causative pathogens was evaluated in 140 infants and children with acute otitis media with effusion." | 3.67 | Bacteriologic and clinical efficacy of cefixime compared with amoxicillin in acute otitis media. ( Howie, VM; Owen, MJ, 1987) |
| " Middle ear fluid was extracted by tympanocentesis 4, 12 and 24 h after dosing and divided into two fractions: with cells (as collected) (C+) and cell-free (C-)." | 2.69 | Interpretation of middle ear fluid concentrations of antibiotics: comparison between ceftibuten, cefixime and azithromycin. ( Arcidiacono, MM; Demartini, G; Dugnani, S; Fraschini, F; Pintucci, JP; Scaglione, F, 1999) |
| "Overall efficacy for treatment of acute otitis media with effusion was not different; however, cefixime appeared more effective for infections caused by beta-lactamase-producing organisms." | 2.67 | Microbiologic and clinical aspects of a trial of once daily cefixime compared with twice daily cefaclor for treatment of acute otitis media in infants and children. ( Chartrand, SA; Harrison, CJ; Pichichero, ME, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (28.57) | 18.7374 |
| 1990's | 10 (71.43) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Friedland, IR | 1 |
| Harrison, CJ | 2 |
| Chartrand, SA | 2 |
| Pichichero, ME | 1 |
| Rodriguez, WJ | 1 |
| Khan, W | 1 |
| Sait, T | 1 |
| Chhabra, OP | 1 |
| Bell, TA | 1 |
| Akram, S | 1 |
| Kohlbrenner, VM | 1 |
| Hemlin, C | 1 |
| Carenfelt, C | 1 |
| Papatziamos, G | 1 |
| Rodriguez, W | 1 |
| Schwartz, R | 1 |
| Pollack, J | 1 |
| Thedinger, B | 1 |
| Block, SL | 1 |
| Hedrick, JA | 1 |
| Scaglione, F | 1 |
| Demartini, G | 1 |
| Dugnani, S | 1 |
| Arcidiacono, MM | 1 |
| Pintucci, JP | 1 |
| Fraschini, F | 1 |
| Stutman, HR | 1 |
| Arguedas, AG | 1 |
| Rosenfeld, RM | 1 |
| Doyle, WJ | 2 |
| Swarts, JD | 1 |
| Seroky, J | 1 |
| Pinero, BP | 1 |
| Piippo, T | 1 |
| Stefansson, S | 1 |
| Pitkäjärvi, T | 1 |
| Lundberg, C | 1 |
| Chonmaitree, T | 1 |
| Owen, MJ | 2 |
| Howie, VM | 2 |
| McLinn, SE | 1 |
| Hotaling, AJ | 1 |
| Cantekin, EI | 1 |
| Kenna, MA | 1 |
| Bluestone, CD | 1 |
| Fall, P | 1 |
| Stephenson, J | 1 |
| Kurs-Lasky, M | 1 |
| Wucher, FP | 1 |
| Blatter, MM | 1 |
| Reisinger, KS | 1 |
2 reviews available for cefixime and Otitis Media with Effusion
| Article | Year |
|---|---|
Cefixime therapy for otitis media.
Topics: Acute Disease; Amoxicillin; Anti-Infective Agents; Cefixime; Cefotaxime; Humans; Otitis Media with E | 1993 |
Comparison of cefprozil with other antibiotic regimens in the treatment of children with acute otitis media.
Topics: Acute Disease; Amoxicillin; Amoxicillin-Potassium Clavulanate Combination; Anti-Infective Agents; Ce | 1992 |
9 trials available for cefixime and Otitis Media with Effusion
| Article | Year |
|---|---|
Microbiologic and clinical aspects of a trial of once daily cefixime compared with twice daily cefaclor for treatment of acute otitis media in infants and children.
Topics: Acute Disease; Anti-Infective Agents; Cefaclor; Cefixime; Cefotaxime; Child; Child, Preschool; Doubl | 1993 |
Cefixime vs. cefaclor in the treatment of acute otitis media in children: a randomized, comparative study.
Topics: Acute Disease; Cefaclor; Cefixime; Cefotaxime; Child; Child, Preschool; Female; Humans; Infant; Male | 1993 |
Single dose of betamethasone in combined medical treatment of secretory otitis media.
Topics: Anti-Bacterial Agents; Anti-Inflammatory Agents; Betamethasone; Cefixime; Cefotaxime; Child; Child, | 1997 |
Interpretation of middle ear fluid concentrations of antibiotics: comparison between ceftibuten, cefixime and azithromycin.
Topics: Acute Disease; Administration, Oral; Adolescent; Anti-Bacterial Agents; Azithromycin; Cefixime; Cefo | 1999 |
Comparison of cefprozil with other antibiotic regimens in the treatment of children with acute otitis media.
Topics: Acute Disease; Amoxicillin; Amoxicillin-Potassium Clavulanate Combination; Anti-Infective Agents; Ce | 1992 |
Double-blind comparison of cefixime and cefaclor in the treatment of acute otitis media in children.
Topics: Acute Disease; Anti-Bacterial Agents; Cefaclor; Cefixime; Cefotaxime; Child; Child, Preschool; Diarr | 1991 |
Respiratory viruses interfere with bacteriologic response to antibiotic in children with acute otitis media.
Topics: Acute Disease; Amoxicillin; Anti-Bacterial Agents; Bacterial Infections; Cefixime; Cefotaxime; Child | 1990 |
Randomized, open label, multicenter trial of cefixime compared with amoxicillin for treatment of acute otitis media with effusion.
Topics: Acute Disease; Amoxicillin; Cefixime; Cefotaxime; Child; Child, Preschool; Clinical Trials as Topic; | 1987 |
Cefixime vs. cefaclor in the treatment of acute otitis media in infants and children.
Topics: Acute Disease; Cefaclor; Cefixime; Cefotaxime; Cephalexin; Child; Child, Preschool; Female; Humans; | 1987 |
4 other studies available for cefixime and Otitis Media with Effusion
| Article | Year |
|---|---|
Middle ear effusion concentrations of cefixime during acute otitis media with effusion and otitis media with effusion.
Topics: Acute Disease; Cefixime; Cefotaxime; Cephalosporins; Child, Preschool; Ear, Middle; Humans; Infant; | 1997 |
Third-generation cephalosporins in the treatment of acute pneumococcal otitis media. An animal study.
Topics: Acoustic Impedance Tests; Acute Disease; Ampicillin; Animals; Cefixime; Cefotaxime; Ceftibuten; Ceph | 1992 |
Efficacy of a new cephalosporin for acute otitis media.
Topics: Ampicillin; Animals; beta-Lactamases; Cefixime; Cefotaxime; Chinchilla; Haemophilus Infections; Haem | 1987 |
Bacteriologic and clinical efficacy of cefixime compared with amoxicillin in acute otitis media.
Topics: Acute Disease; Amoxicillin; Bacteria; Cefixime; Cefotaxime; Humans; Microbial Sensitivity Tests; Oti | 1987 |