cefixime has been researched along with Liver Cirrhosis in 2 studies
Cefixime: A third-generation cephalosporin antibiotic that is stable to hydrolysis by beta-lactamases.
cefixime : A third-generation cephalosporin antibiotic bearing vinyl and (2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-[(carboxymethoxy)imino]acetamido groups at positions 3 and 7, respectively, of the cephem skeleton. It is used in the treatment of gonorrhoea, tonsilitis, pharyngitis, bronchitis, and urinary tract infections.
Liver Cirrhosis: Liver disease in which the normal microcirculation, the gross vascular anatomy, and the hepatic architecture have been variably destroyed and altered with fibrous septa surrounding regenerated or regenerating parenchymal nodules.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The elimination half-life varies between 3 and 4 hours." | 1.28 | [Pharmacokinetic properties of cefixime]. ( Barré, J, 1989) |
| "Cefixime was administered as a single dose of 200 mg and levels were measured by HPLC." | 1.28 | [Effect of hepatic failure upon the pharmacokinetics of cefixime]. ( Gaudin, C; Lebrec, D; Montay, G; Roche, G; Singlas, E; Taburet, AM, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Barré, J | 1 |
| Singlas, E | 1 |
| Lebrec, D | 1 |
| Gaudin, C | 1 |
| Montay, G | 1 |
| Roche, G | 1 |
| Taburet, AM | 1 |
2 other studies available for cefixime and Liver Cirrhosis
| Article | Year |
|---|---|
[Pharmacokinetic properties of cefixime].
Topics: Administration, Oral; Adolescent; Adult; Aged; Biological Availability; Cefixime; Cefotaxime; Child; | 1989 |
[Effect of hepatic failure upon the pharmacokinetics of cefixime].
Topics: Adult; Aged; Cefixime; Cefotaxime; Female; Half-Life; Humans; Liver Cirrhosis; Male; Metabolic Clear | 1989 |