cefixime has been researched along with Kidney Failure, Chronic in 4 studies
Cefixime: A third-generation cephalosporin antibiotic that is stable to hydrolysis by beta-lactamases.
cefixime : A third-generation cephalosporin antibiotic bearing vinyl and (2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-[(carboxymethoxy)imino]acetamido groups at positions 3 and 7, respectively, of the cephem skeleton. It is used in the treatment of gonorrhoea, tonsilitis, pharyngitis, bronchitis, and urinary tract infections.
Kidney Failure, Chronic: The end-stage of CHRONIC RENAL INSUFFICIENCY. It is characterized by the severe irreversible kidney damage (as measured by the level of PROTEINURIA) and the reduction in GLOMERULAR FILTRATION RATE to less than 15 ml per min (Kidney Foundation: Kidney Disease Outcome Quality Initiative, 2002). These patients generally require HEMODIALYSIS or KIDNEY TRANSPLANTATION.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The elimination half-life varies between 3 and 4 hours." | 1.28 | [Pharmacokinetic properties of cefixime]. ( Barré, J, 1989) |
| " Apparent total body, renal, and apparent nondialysis-nonrenal clearances and protein binding declined and elimination half-life increased with decreasing creatinine clearance." | 1.27 | Pharmacokinetics of cefixime (CL 284,635; FK 027) in healthy subjects and patients with renal insufficiency. ( Brown, GR; Guay, DR; Harding, GK; Meatherall, RC, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (50.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Demir, T | 1 |
| Dadali, M | 1 |
| Kuroyama, M | 1 |
| Kumano, K | 1 |
| Motohashi, S | 1 |
| Murase, S | 1 |
| Tomonaga, F | 1 |
| Barré, J | 1 |
| Guay, DR | 1 |
| Meatherall, RC | 1 |
| Harding, GK | 1 |
| Brown, GR | 1 |
4 other studies available for cefixime and Kidney Failure, Chronic
| Article | Year |
|---|---|
Recurrent complicated urinary tract infection due to rare pathogen Sphingomonas paucimobilis: contamination or real deal?
Topics: Anti-Bacterial Agents; Cefixime; Community-Acquired Infections; Diabetes Mellitus, Type 1; Diabetic | 2016 |
[Protein binding of oral cephems in patients with chronic renal failure].
Topics: Carrier Proteins; Cefdinir; Cefixime; Cefotaxime; Ceftibuten; Cephalosporins; Humans; Kidney Failure | 1993 |
[Pharmacokinetic properties of cefixime].
Topics: Administration, Oral; Adolescent; Adult; Aged; Biological Availability; Cefixime; Cefotaxime; Child; | 1989 |
Pharmacokinetics of cefixime (CL 284,635; FK 027) in healthy subjects and patients with renal insufficiency.
Topics: Adult; Aged; Cefixime; Cefotaxime; Female; Humans; Kidney Failure, Chronic; Kinetics; Male; Middle A | 1986 |