Page last updated: 2024-10-24

cefixime and Acute Disease

cefixime has been researched along with Acute Disease in 62 studies

Cefixime: A third-generation cephalosporin antibiotic that is stable to hydrolysis by beta-lactamases.
cefixime : A third-generation cephalosporin antibiotic bearing vinyl and (2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-[(carboxymethoxy)imino]acetamido groups at positions 3 and 7, respectively, of the cephem skeleton. It is used in the treatment of gonorrhoea, tonsilitis, pharyngitis, bronchitis, and urinary tract infections.

Acute Disease: Disease having a short and relatively severe course.

Research Excerpts

ExcerptRelevanceReference
"To compare the efficacy of cefixime with amoxicillin in the treatment of acute otitis media in children."9.07Efficacy of cefixime in the treatment of acute otitis media in children. ( Anwar, R; Bannister, ER; Howie, VM; Nguyen, HK; Owen, MJ; Swank, PR, 1993)
"Cefixime was compared with amoxicillin for treatment of acute otitis media in a randomized trial."9.07Cefixime compared with amoxicillin for treatment of acute otitis media. ( Carlin, SA; Christopher, NC; Johnson, CE; Rehmus, JM; Roberts, DG; Shurin, PA; Super, DM; Whitwell, JK, 1991)
"A comparative study of cefixime (CFIX), a new oral cephem antibiotic, was carried out at the Department of Urology, Nagoya University Hospital and its four affiliated hospitals to evaluate the clinical efficacy and safety of two dosage regimens of CFIX, given either in twice daily doses (BID group) or once daily dose (UID group), in the treatment of acute uncomplicated cystitis."9.07[Clinical evaluation of usefulness of cefixime (200 mg administered once daily) in the treatment of acute uncomplicated cystitis]. ( Hattori, R; Ito, Y; Kinukawa, T; Miyake, K; Narushima, M; Obata, K; Otani, T; Sakata, T; Takita, T, 1992)
"In a noncomparative trial, 73 adults with acute sinusitis confirmed by x-ray received cefixime 400mg once daily for approximately 10 days."9.07Clinical efficacy and tolerability of cefixime in the treatment of acute sinusitis. ( Berche, P; Boucot, I; Gehanno, P; Uhlrich, J, 1991)
" The aim of this study was to compare the clinical efficacy of cefixime with that of amoxicillin in the treatment of acute otitis media in 40 children."9.07Cefixime vs amoxicillin in the treatment of acute otitis media in infants and children. ( Marchisio, P; Principi, N, 1991)
"A large scale multicentre clinical study was undertaken to assess the efficacy and tolerability of cefixime in the treatment of acute otitis media in children."9.07Efficacy and tolerability of cefixime in otitis media. A multicentre study in over 25,000 children. ( Wu, DH, 1991)
"A double blind study was carried out to compare the efficacy and safety of cefixime (CFIX), a new oral cephem with cefaclor (CCL) in the treatment of 245 children weighing 10 approximately 30 kg, with acute suppurative otitis media."9.06[A parallel comparative double blind study of cefixime with cefaclor in the treatment of acute suppurative otitis media in children]. ( Baba, S; Itoh, Y; Kawamura, S; Kinoshita, H; Kobayashi, K; Mori, Y; Onishi, S; Shimada, J; Suzuki, K; Ueda, R, 1987)
"In this 31-site multicenter trial, 565 adult patients with urinary tract infections were randomly assigned to receive either a 10-day course of cefixime 400 mg once daily (n = 279) or amoxicillin 250 mg three times daily (n = 286)."9.06A double-blind, multicenter, comparative study of the safety and efficacy of cefixime versus amoxicillin in the treatment of acute urinary tract infections in adult patients. ( Bryant, A; Iravani, A; Johnson, D; Richard, GA, 1988)
"A total of 325 eligible paediatric patients were entered into an open, randomised, multicentre general practice study to assess the comparative efficacy of a new third-generation oral cephalosporin, cefixime, with respect to that of amoxycillin in the treatment of acute otitis media."9.06A general practice comparative study of a new third-generation oral cephalosporin, cefixime, with amoxycillin in the treatment of acute paediatric otitis media. ( Leigh, AP; Millar, ED; Robinson, D, 1989)
"Cefixime (CFIX) was administered 200 mg (2 divided doses) per day to 154 female patients with acute uncomplicated cystitis."9.06[Clinical evaluation of cefixime in the treatment of acute uncomplicated cystitis]. ( Arakawa, M; Asano, Y; Gotoh, T; Imanaka, K; Kakizaki, H; Koyanagi, T; Kubota, M; Nagamori, S; Nonomura, K; Togashi, M, 1989)
"Cefixime is a new oral cephalosporin with the same activity as that of third generation cephalosporins, particularly against organisms responsible for lower respiratory tract infections."9.06[Efficacy and tolerability of cefixime in lower respiratory tract infections in adults. French multicentric study]. ( Modai, J, 1989)
"Patients with purulent exacerbation of chronic bronchitis were randomized to receive either a single 400-mg daily dose of cefixime or 250 mg of cephalexin, orally, four times a day."9.06Randomized comparative study of cefixime versus cephalexin in acute bacterial exacerbations of chronic bronchitis. ( Kalbfleisch, JH; Roberson, D; Sarubbi, F; Verghese, A, 1990)
"In a prospective, open clinical study, 50 urological patients with acute pyelonephritis were treated with the oral cephalosporin cefixime."9.06[Effectiveness and tolerance of cefixime in the treatment of acute pyelonephritis]. ( Segal, A; Tröster, K; Weissbach, L, 1990)
"The clinical efficacy and safety of cefixime (CFIX), a new oral cephalosporin, were compared with those of cefroxadine (CXD) in patients suffering from acute lacunar tonsillitis in a double blind study."9.06[A parallel comparative double blind study of cefixime with cefroxadine in the treatment of acute lacunar tonsillitis]. ( Asai, H; Itoh, Y; Kawamura, S; Kobayashi, K; Matsunaga, T; Ogino, H; Onishi, S; Sakamoto, Y; Shiraishi, T; Ueda, R, 1987)
"Cefixime, a new third generation cephalosporin antibiotic for oral use, was evaluated for safety and efficacy in the treatment of children with acute otitis media with effusion."9.06Randomized, open label, multicenter trial of cefixime compared with amoxicillin for treatment of acute otitis media with effusion. ( McLinn, SE, 1987)
" In two trials, 891 pediatric patients were enrolled to either cefprozil or amoxicillin-clavulanate dosage regimens."7.77Multi-investigator evaluation of the efficacy and safety of cefprozil, amoxicillin-clavulanate, cefixime and cefaclor in the treatment of acute otitis media. ( Kafetzis, DA, 1994)
"In a clinical study, 40 patients suffering from acute, recurrent or chronic sinusitis were treated with cefixime."7.68[Cefixime therapy in sinusitis]. ( Jorde, W; Schata, M, 1990)
"Cefixime seems to be an acceptable alternative to the regimens containing an aminopenicillin and an aminoglycoside for the treatment of community-acquired non-complicated APN."6.69[Cefixime versus amoxicillin plus netilmicin in the treatment of community-acquired non-complicated acute pyelonephritis]. ( Almela, M; García San Miguel, J; Marco, F; Martínez, JA; Mensa, J; Moreno-Martínez, A; Soriano, E; Vila, J, 1998)
"0001), and the adverse experience rate was lower (P = 0."6.68Comparison of the efficacy, safety and acceptability of cefixime and amoxicillin/clavulanate in acute otitis media. ( Gooch, WM; Philips, A; Rhoades, R; Rosenberg, R; Schaten, R; Starobin, S, 1997)
"Cefixime was effective in the treatment of bacterial sinus infections in adults and was well tolerated."6.67Evaluation of cefixime in the treatment of bacterial maxillary sinusitis. ( Edelstein, DR; Kimmelman, CP; Kohlbrenner, VM; Kohut, RI; Marinaccio, AT; Matthews, BL; McCaffrey, TV; Parnes, SM; Rapp, M; Rybak, LP, 1993)
"Previous studies using the chinchilla animal model demonstrated that the third generation cephalosporin cefixime (Suprax) with split dosing was as effective as ampicillin in sterilizing the middle ear cleft when infected with S."5.29An experimental study of cefixime in the treatment of Streptococcus pneumoniae otitis media. ( Dolitsky, JN; Doyle, WJ; Magit, AE; Rosenfeld, RM; Seroky, JT; Swarts, JD, 1994)
"Cefixime is a new third generation oral cephalosporin that exhibits excellent antibacterial activity against Neisseria gonorrhoeae, including beta-lactamase-positive strains."5.28[Cefixime therapy in patients with proven gonorrhea]. ( Backhaus, A; Tinzl, J, 1990)
"To compare the short-term effectiveness of ceftriaxone single dose followed by cefixime with a standard treatment of acute uncomplicated pyelonephritis in women."5.10Short-term effectiveness of ceftriaxone single dose in the initial treatment of acute uncomplicated pyelonephritis in women. A randomised controlled trial. ( Collvinent, B; Horcajada, JP; Marco, F; Mensa, J; Millá, J; Miró, O; Moreno, A; Sanchez, M, 2002)
"To compare the efficacy of cefixime with amoxicillin in the treatment of acute otitis media in children."5.07Efficacy of cefixime in the treatment of acute otitis media in children. ( Anwar, R; Bannister, ER; Howie, VM; Nguyen, HK; Owen, MJ; Swank, PR, 1993)
"A comparative study of cefixime (CFIX), a new oral cephem antibiotic, was carried out at the Department of Urology, Nagoya University Hospital and its four affiliated hospitals to evaluate the clinical efficacy and safety of two dosage regimens of CFIX, given either in twice daily doses (BID group) or once daily dose (UID group), in the treatment of acute uncomplicated cystitis."5.07[Clinical evaluation of usefulness of cefixime (200 mg administered once daily) in the treatment of acute uncomplicated cystitis]. ( Hattori, R; Ito, Y; Kinukawa, T; Miyake, K; Narushima, M; Obata, K; Otani, T; Sakata, T; Takita, T, 1992)
"In a noncomparative trial, 73 adults with acute sinusitis confirmed by x-ray received cefixime 400mg once daily for approximately 10 days."5.07Clinical efficacy and tolerability of cefixime in the treatment of acute sinusitis. ( Berche, P; Boucot, I; Gehanno, P; Uhlrich, J, 1991)
" The aim of this study was to compare the clinical efficacy of cefixime with that of amoxicillin in the treatment of acute otitis media in 40 children."5.07Cefixime vs amoxicillin in the treatment of acute otitis media in infants and children. ( Marchisio, P; Principi, N, 1991)
"A large scale multicentre clinical study was undertaken to assess the efficacy and tolerability of cefixime in the treatment of acute otitis media in children."5.07Efficacy and tolerability of cefixime in otitis media. A multicentre study in over 25,000 children. ( Wu, DH, 1991)
"Cefixime was compared with amoxicillin for treatment of acute otitis media in a randomized trial."5.07Cefixime compared with amoxicillin for treatment of acute otitis media. ( Carlin, SA; Christopher, NC; Johnson, CE; Rehmus, JM; Roberts, DG; Shurin, PA; Super, DM; Whitwell, JK, 1991)
"Patients with purulent exacerbation of chronic bronchitis were randomized to receive either a single 400-mg daily dose of cefixime or 250 mg of cephalexin, orally, four times a day."5.06Randomized comparative study of cefixime versus cephalexin in acute bacterial exacerbations of chronic bronchitis. ( Kalbfleisch, JH; Roberson, D; Sarubbi, F; Verghese, A, 1990)
"Cefixime is a new oral cephalosporin with the same activity as that of third generation cephalosporins, particularly against organisms responsible for lower respiratory tract infections."5.06[Efficacy and tolerability of cefixime in lower respiratory tract infections in adults. French multicentric study]. ( Modai, J, 1989)
"Cefixime (CFIX) was administered 200 mg (2 divided doses) per day to 154 female patients with acute uncomplicated cystitis."5.06[Clinical evaluation of cefixime in the treatment of acute uncomplicated cystitis]. ( Arakawa, M; Asano, Y; Gotoh, T; Imanaka, K; Kakizaki, H; Koyanagi, T; Kubota, M; Nagamori, S; Nonomura, K; Togashi, M, 1989)
"A total of 325 eligible paediatric patients were entered into an open, randomised, multicentre general practice study to assess the comparative efficacy of a new third-generation oral cephalosporin, cefixime, with respect to that of amoxycillin in the treatment of acute otitis media."5.06A general practice comparative study of a new third-generation oral cephalosporin, cefixime, with amoxycillin in the treatment of acute paediatric otitis media. ( Leigh, AP; Millar, ED; Robinson, D, 1989)
"In this 31-site multicenter trial, 565 adult patients with urinary tract infections were randomly assigned to receive either a 10-day course of cefixime 400 mg once daily (n = 279) or amoxicillin 250 mg three times daily (n = 286)."5.06A double-blind, multicenter, comparative study of the safety and efficacy of cefixime versus amoxicillin in the treatment of acute urinary tract infections in adult patients. ( Bryant, A; Iravani, A; Johnson, D; Richard, GA, 1988)
"A double blind study was carried out to compare the efficacy and safety of cefixime (CFIX), a new oral cephem with cefaclor (CCL) in the treatment of 245 children weighing 10 approximately 30 kg, with acute suppurative otitis media."5.06[A parallel comparative double blind study of cefixime with cefaclor in the treatment of acute suppurative otitis media in children]. ( Baba, S; Itoh, Y; Kawamura, S; Kinoshita, H; Kobayashi, K; Mori, Y; Onishi, S; Shimada, J; Suzuki, K; Ueda, R, 1987)
"The clinical efficacy and safety of cefixime (CFIX), a new oral cephalosporin, were compared with those of cefroxadine (CXD) in patients suffering from acute lacunar tonsillitis in a double blind study."5.06[A parallel comparative double blind study of cefixime with cefroxadine in the treatment of acute lacunar tonsillitis]. ( Asai, H; Itoh, Y; Kawamura, S; Kobayashi, K; Matsunaga, T; Ogino, H; Onishi, S; Sakamoto, Y; Shiraishi, T; Ueda, R, 1987)
"Cefixime, a new third generation cephalosporin antibiotic for oral use, was evaluated for safety and efficacy in the treatment of children with acute otitis media with effusion."5.06Randomized, open label, multicenter trial of cefixime compared with amoxicillin for treatment of acute otitis media with effusion. ( McLinn, SE, 1987)
"In a prospective, open clinical study, 50 urological patients with acute pyelonephritis were treated with the oral cephalosporin cefixime."5.06[Effectiveness and tolerance of cefixime in the treatment of acute pyelonephritis]. ( Segal, A; Tröster, K; Weissbach, L, 1990)
" In two trials, 891 pediatric patients were enrolled to either cefprozil or amoxicillin-clavulanate dosage regimens."3.77Multi-investigator evaluation of the efficacy and safety of cefprozil, amoxicillin-clavulanate, cefixime and cefaclor in the treatment of acute otitis media. ( Kafetzis, DA, 1994)
" Using the chinchilla animal model, we compared the efficacy of ceftibuten (n = 33) with that of saline (n = 34), ampicillin (n = 32), and cefixime (n = 31) for the treatment of acute otitis media caused by beta-lactamase-producing nontypeable Hemophilus influenzae."3.68Efficacy of ceftibuten for acute otitis media caused by Hemophilus influenzae: an animal study. ( Doyle, WJ; Greene, I; Rosenfeld, RM; Seroky, J; Swarts, JD, 1993)
"In a clinical study, 40 patients suffering from acute, recurrent or chronic sinusitis were treated with cefixime."3.68[Cefixime therapy in sinusitis]. ( Jorde, W; Schata, M, 1990)
"The ability of cefixime or amoxicillin to eradicate causative pathogens was evaluated in 140 infants and children with acute otitis media with effusion."3.67Bacteriologic and clinical efficacy of cefixime compared with amoxicillin in acute otitis media. ( Howie, VM; Owen, MJ, 1987)
"Cefixime (CFIX) was given orally to 25 children with acute bacterial infections including 13 with acute tonsillitis, 1 with acute tonsillitis and cervical lymphadenitis, 1 with acute bronchitis, 5 with bronchopneumonia and 5 with urinary tract infection."3.67[Clinical experience with cefixime in the pediatric field]. ( Aihara, R; Kobashi, H; Nishioka, A; Ohara, K; Okamoto, T, 1986)
"Topical therapy of bacterial conjunctivitis achieves a clinical cure but does not prevent acute otitis media (AOM)."2.70Short term oral cefixime therapy for treatment of bacterial conjunctivitis. ( Greenberg, D; Hoberman, A; Wald, ER, 2001)
" Middle ear fluid was extracted by tympanocentesis 4, 12 and 24 h after dosing and divided into two fractions: with cells (as collected) (C+) and cell-free (C-)."2.69Interpretation of middle ear fluid concentrations of antibiotics: comparison between ceftibuten, cefixime and azithromycin. ( Arcidiacono, MM; Demartini, G; Dugnani, S; Fraschini, F; Pintucci, JP; Scaglione, F, 1999)
"Cefixime seems to be an acceptable alternative to the regimens containing an aminopenicillin and an aminoglycoside for the treatment of community-acquired non-complicated APN."2.69[Cefixime versus amoxicillin plus netilmicin in the treatment of community-acquired non-complicated acute pyelonephritis]. ( Almela, M; García San Miguel, J; Marco, F; Martínez, JA; Mensa, J; Moreno-Martínez, A; Soriano, E; Vila, J, 1998)
"0001), and the adverse experience rate was lower (P = 0."2.68Comparison of the efficacy, safety and acceptability of cefixime and amoxicillin/clavulanate in acute otitis media. ( Gooch, WM; Philips, A; Rhoades, R; Rosenberg, R; Schaten, R; Starobin, S, 1997)
"Cefixime was effective in the treatment of bacterial sinus infections in adults and was well tolerated."2.67Evaluation of cefixime in the treatment of bacterial maxillary sinusitis. ( Edelstein, DR; Kimmelman, CP; Kohlbrenner, VM; Kohut, RI; Marinaccio, AT; Matthews, BL; McCaffrey, TV; Parnes, SM; Rapp, M; Rybak, LP, 1993)
"Overall efficacy for treatment of acute otitis media with effusion was not different; however, cefixime appeared more effective for infections caused by beta-lactamase-producing organisms."2.67Microbiologic and clinical aspects of a trial of once daily cefixime compared with twice daily cefaclor for treatment of acute otitis media in infants and children. ( Chartrand, SA; Harrison, CJ; Pichichero, ME, 1993)
"Cefixime was kept for patients not responding to the first GU treatment."1.31Cost-effectiveness of management strategies for acute urethritis in the developing world. ( Crabbé, F; de Clerck, M; Laga, M; Vuylsteke, B, 2000)
"Previous studies using the chinchilla animal model demonstrated that the third generation cephalosporin cefixime (Suprax) with split dosing was as effective as ampicillin in sterilizing the middle ear cleft when infected with S."1.29An experimental study of cefixime in the treatment of Streptococcus pneumoniae otitis media. ( Dolitsky, JN; Doyle, WJ; Magit, AE; Rosenfeld, RM; Seroky, JT; Swarts, JD, 1994)
"Cefixime is a new third generation oral cephalosporin that exhibits excellent antibacterial activity against Neisseria gonorrhoeae, including beta-lactamase-positive strains."1.28[Cefixime therapy in patients with proven gonorrhea]. ( Backhaus, A; Tinzl, J, 1990)
"Twenty-one pediatric patients with bacterial infections (10, tonsillitis; 4, pharyngitis; and 7, urinary tract infections) were treated with CFIX at doses of 1."1.27[Fundamental and clinical studies on cefixime in the pediatric field]. ( Hakamada, S; Hayakawa, F; Kuno, K; Miyachi, Y; Nakashima, S; Nakashima, T, 1986)
"Cefixime (CFIX) was evaluated for pharmacokinetics, therapeutic effectiveness on infection, safety, and bacteriological effectiveness in pediatrics."1.27[Fundamental and clinical studies on cefixime in pediatric field]. ( Kida, K; Matsuda, H; Miyazaki, M; Murase, M, 1986)
" The mean half-life and the mean AUC values were 2."1.27[Pharmacokinetics and clinical effects of cefixime in pediatrics]. ( Ishimoto, K; Koga, T; Motohiro, T; Nagayama, K; Nishiyama, T; Shimada, Y; Tanaka, K; Tominaga, K; Tomita, S; Yamashita, F, 1986)

Research

Studies (62)

TimeframeStudies, this research(%)All Research%
pre-199016 (25.81)18.7374
1990's38 (61.29)18.2507
2000's6 (9.68)29.6817
2010's2 (3.23)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bocquet, N1
Sergent Alaoui, A1
Jais, JP1
Gajdos, V1
Guigonis, V1
Lacour, B1
Chéron, G1
Sengupta, J1
Mondal, AK1
Jain, P1
Garg, RD1
Mathur, NC1
Moharana, AK1
Principi, N2
Marchisio, P2
Grasso, R1
Filiberti, G1
Blatto, M1
de La Vaissière, B1
Castello, B1
Quinet, B1
Cohen, R1
Grimprel, E1
Dalla Vestra, M1
Rettore, C1
Sartore, P1
Velo, E1
Sasset, L1
Chiesa, G1
Marcon, L1
Scarano, L1
Simioni, N1
Bacelle, L1
Patrassi, GM1
Tomiyama, M1
Kafetzis, DA1
Asmar, BI1
Dajani, AS1
Del Beccaro, MA2
Mendelman, PM2
Magit, AE1
Dolitsky, JN1
Doyle, WJ3
Swarts, JD3
Seroky, JT1
Rosenfeld, RM3
Friedland, IR1
Hefelfinger, DC1
Berman, S1
Roark, R1
Harrison, CJ2
Chartrand, SA2
Pichichero, ME1
Rodriguez, WJ1
Khan, W1
Sait, T1
Chhabra, OP1
Bell, TA1
Akram, S1
Kohlbrenner, VM2
Owen, MJ3
Anwar, R1
Nguyen, HK1
Swank, PR1
Bannister, ER1
Howie, VM3
Matthews, BL1
Kohut, RI1
Edelstein, DR1
Rybak, LP1
Rapp, M1
McCaffrey, TV1
Kimmelman, CP1
Parnes, SM1
Marinaccio, AT1
Seroky, J2
Greene, I1
Boulesteix, J1
Bégué, P1
Dubreuil, C1
Mégraud, F1
Dabernat, H1
Geslin, P1
de La Rocque, F1
Trinh, A1
Chapman, PA1
Siddons, CA1
Gooch, WM1
Philips, A1
Rhoades, R1
Rosenberg, R1
Schaten, R1
Starobin, S1
Rodriguez, W1
Schwartz, R1
Pollack, J1
Thedinger, B1
Block, SL1
Hedrick, JA1
Moreno-Martínez, A1
Mensa, J2
Martínez, JA1
Marco, F2
Vila, J1
Almela, M1
García San Miguel, J1
Soriano, E1
Scaglione, F1
Demartini, G1
Dugnani, S1
Arcidiacono, MM1
Pintucci, JP1
Fraschini, F1
Hoberman, A2
Wald, ER2
Hickey, RW1
Baskin, M1
Charron, M1
Majd, M1
Kearney, DH1
Reynolds, EA1
Ruley, J1
Janosky, JE1
Crabbé, F1
Vuylsteke, B1
de Clerck, M1
Laga, M1
Greenberg, D1
Sanchez, M1
Collvinent, B1
Miró, O1
Horcajada, JP1
Moreno, A1
Millá, J1
Kumamoto, Y1
Sakata, T1
Miyake, K1
Kinukawa, T1
Hattori, R1
Obata, K1
Otani, T1
Narushima, M1
Ito, Y1
Takita, T1
Wiedermann, BL1
Schwartz, RH1
Stutman, HR1
Arguedas, AG1
Asbach, HW1
Gehanno, P1
Boucot, I1
Berche, P1
Uhlrich, J1
Wu, DH1
Pinero, BP1
Marchant, CD1
Carlin, SA2
Johnson, CE2
Shurin, PA2
Inglis, AF1
Richardson, MA1
Duncan, NO1
Clausen, CR1
Stull, TL1
Charles, D1
Bluestone, MD1
Super, DM1
Rehmus, JM1
Roberts, DG1
Christopher, NC1
Whitwell, JK1
Piippo, T1
Stefansson, S1
Pitkäjärvi, T1
Lundberg, C1
Jorde, W1
Schata, M1
Weissbach, L1
Segal, A1
Tröster, K1
Backhaus, A1
Tinzl, J1
Verghese, A1
Roberson, D1
Kalbfleisch, JH1
Sarubbi, F1
Chonmaitree, T1
Modai, J1
Togashi, M1
Kubota, M1
Nagamori, S1
Asano, Y1
Imanaka, K1
Gotoh, T1
Nonomura, K1
Koyanagi, T1
Arakawa, M1
Kakizaki, H1
Leigh, AP1
Robinson, D1
Millar, ED1
Iravani, A1
Richard, GA1
Johnson, D1
Bryant, A1
Baba, S1
Kinoshita, H1
Mori, Y1
Suzuki, K1
Shimada, J1
Kawamura, S2
Onishi, S2
Ueda, R2
Kobayashi, K2
Itoh, Y2
Matsunaga, T1
Ogino, H1
Asai, H1
Shiraishi, T1
Sakamoto, Y1
McLinn, SE1
Nishimura, T1
Takashima, T1
Tabuki, K1
Takagi, M1
Kenna, MA1
Bluestone, CD1
Fall, P1
Stephenson, J1
Kurs-Lasky, M1
Wucher, FP1
Blatter, MM1
Reisinger, KS1
Nakashima, S1
Hayakawa, F1
Nakashima, T1
Miyachi, Y1
Hakamada, S1
Kuno, K1
Furukawa, S1
Okada, T1
Aihara, R1
Kobashi, H1
Nishioka, A1
Ohara, K1
Okamoto, T1
Miyazaki, M1
Kida, K1
Matsuda, H1
Murase, M1
Motohiro, T1
Tanaka, K1
Koga, T1
Shimada, Y1
Tomita, S1
Nishiyama, T1
Ishimoto, K1
Tominaga, K1
Yamashita, F1
Nagayama, K1

Clinical Trials (3)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Treatment of Acute Pyelonephritis With Gram Negative Strains in Infants and Children Less Than 3 Years Old. Cefixime PO 10d vs Ceftriaxone IV 4d Followed by Cefixime PO 6d. Multicenter, Randomised Trial of Equivalence.[NCT00136656]Phase 4700 participants (Actual)Interventional2005-07-31Completed
Evaluation of the Effectiveness of Antibiotic Prophylaxis in Children With a History of Upper Urinary Tract Infections:a Multicentre Randomised Study[NCT00156546]Phase 4660 participants Interventional2000-05-31Active, not recruiting
A Multicenter Randomized Controlled Trial of Antibiotic Treatment in Children With Urinary Tract Infections: Oral Amoxicillin/Clavulanic Acid vs Initial iv Ceftriaxone.[NCT00161330]Phase 3440 participants Interventional2000-06-30Terminated
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

4 reviews available for cefixime and Acute Disease

ArticleYear
Acute pyelonephritis in children: antibiotic therapy depending on the clinical context.
    Prescrire international, 2010, Volume: 19, Issue:108

    Topics: Acute Disease; Anti-Bacterial Agents; Cefixime; Ceftriaxone; Child; Child, Preschool; Humans; Microb

2010
Multi-investigator evaluation of the efficacy and safety of cefprozil, amoxicillin-clavulanate, cefixime and cefaclor in the treatment of acute otitis media.
    European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 1994, Volume: 13, Issue:10

    Topics: Acute Disease; Amoxicillin; Amoxicillin-Potassium Clavulanate Combination; Anti-Bacterial Agents; Ba

1994
Cefixime therapy for otitis media.
    The Pediatric infectious disease journal, 1993, Volume: 12, Issue:6

    Topics: Acute Disease; Amoxicillin; Anti-Infective Agents; Cefixime; Cefotaxime; Humans; Otitis Media with E

1993
Comparison of cefprozil with other antibiotic regimens in the treatment of children with acute otitis media.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 1992, Volume: 14 Suppl 2

    Topics: Acute Disease; Amoxicillin; Amoxicillin-Potassium Clavulanate Combination; Anti-Infective Agents; Ce

1992

Trials

39 trials available for cefixime and Acute Disease

ArticleYear
Randomized trial of oral versus sequential IV/oral antibiotic for acute pyelonephritis in children.
    Pediatrics, 2012, Volume: 129, Issue:2

    Topics: Acute Disease; Administration, Oral; Anti-Bacterial Agents; Calcitonin; Calcitonin Gene-Related Pept

2012
Comparative evaluation of cefpodoxime versus cefixime in children with lower respiratory tract infections.
    Indian journal of pediatrics, 2004, Volume: 71, Issue:6

    Topics: Acute Disease; Anti-Bacterial Agents; Cefixime; Cefpodoxime; Ceftizoxime; Child; Child, Preschool; F

2004
[The effect of cefaclor and cefixime on nasopharyngeal pathogens in children].
    Nihon Jibiinkoka Gakkai kaiho, 1995, Volume: 98, Issue:4

    Topics: Acute Disease; Anti-Bacterial Agents; Bacteria; Cefaclor; Cefixime; Cefotaxime; Child; Child, Presch

1995
Multi-investigator evaluation of the efficacy and safety of cefprozil, amoxicillin-clavulanate, cefixime and cefaclor in the treatment of acute otitis media.
    European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 1994, Volume: 13, Issue:10

    Topics: Acute Disease; Amoxicillin; Amoxicillin-Potassium Clavulanate Combination; Anti-Bacterial Agents; Ba

1994
Comparison of cefpodoxime proxetil and cefixime in the treatment of acute otitis media in infants and children. Otitis Study Group.
    Pediatrics, 1994, Volume: 94, Issue:6 Pt 1

    Topics: Acute Disease; Adolescent; Anti-Infective Agents; Cefixime; Cefotaxime; Cefpodoxime Proxetil; Ceftiz

1994
Factors influencing outcome in children treated with antibiotics for acute otitis media.
    The Pediatric infectious disease journal, 1993, Volume: 12, Issue:1

    Topics: Acute Disease; Amoxicillin; Anti-Bacterial Agents; Cefaclor; Cefixime; Cefotaxime; Cephalosporins; C

1993
Microbiologic and clinical aspects of a trial of once daily cefixime compared with twice daily cefaclor for treatment of acute otitis media in infants and children.
    The Pediatric infectious disease journal, 1993, Volume: 12, Issue:1

    Topics: Acute Disease; Anti-Infective Agents; Cefaclor; Cefixime; Cefotaxime; Child; Child, Preschool; Doubl

1993
Cefixime vs. cefaclor in the treatment of acute otitis media in children: a randomized, comparative study.
    The Pediatric infectious disease journal, 1993, Volume: 12, Issue:1

    Topics: Acute Disease; Cefaclor; Cefixime; Cefotaxime; Child; Child, Preschool; Female; Humans; Infant; Male

1993
Efficacy of cefixime in the treatment of acute otitis media in children.
    American journal of diseases of children (1960), 1993, Volume: 147, Issue:1

    Topics: Acute Disease; Administration, Oral; Amoxicillin; Anti-Infective Agents; Cefixime; Cefotaxime; Child

1993
Evaluation of cefixime in the treatment of bacterial maxillary sinusitis.
    Southern medical journal, 1993, Volume: 86, Issue:3

    Topics: Acute Disease; Administration, Oral; Adult; Aged; Aged, 80 and over; Anti-Infective Agents; Bacteria

1993
Acute otitis media in children: a study of nasopharyngeal carriage of potential pathogens and therapeutic efficacy of cefixime and amoxicillin-clavulanate.
    Infection, 1995, Volume: 23 Suppl 2

    Topics: Acute Disease; Amoxicillin; Amoxicillin-Potassium Clavulanate Combination; Bacteria; Cefixime; Cefot

1995
Comparison of the efficacy, safety and acceptability of cefixime and amoxicillin/clavulanate in acute otitis media.
    The Pediatric infectious disease journal, 1997, Volume: 16, Issue:2 Suppl

    Topics: Acute Disease; Amoxicillin; Amoxicillin-Potassium Clavulanate Combination; Cefixime; Cefotaxime; Cep

1997
[Cefixime versus amoxicillin plus netilmicin in the treatment of community-acquired non-complicated acute pyelonephritis].
    Medicina clinica, 1998, Oct-31, Volume: 111, Issue:14

    Topics: Acute Disease; Adult; Aged; Amoxicillin; Bacteremia; Cefixime; Cefotaxime; Cephalosporins; Communica

1998
Interpretation of middle ear fluid concentrations of antibiotics: comparison between ceftibuten, cefixime and azithromycin.
    British journal of clinical pharmacology, 1999, Volume: 47, Issue:3

    Topics: Acute Disease; Administration, Oral; Adolescent; Anti-Bacterial Agents; Azithromycin; Cefixime; Cefo

1999
Oral versus initial intravenous therapy for urinary tract infections in young febrile children.
    Pediatrics, 1999, Volume: 104, Issue:1 Pt 1

    Topics: Acute Disease; Administration, Oral; Cefixime; Cefotaxime; Cephalosporins; Cost-Benefit Analysis; Fe

1999
Oral versus initial intravenous therapy for urinary tract infections in young febrile children.
    Pediatrics, 1999, Volume: 104, Issue:1 Pt 1

    Topics: Acute Disease; Administration, Oral; Cefixime; Cefotaxime; Cephalosporins; Cost-Benefit Analysis; Fe

1999
Oral versus initial intravenous therapy for urinary tract infections in young febrile children.
    Pediatrics, 1999, Volume: 104, Issue:1 Pt 1

    Topics: Acute Disease; Administration, Oral; Cefixime; Cefotaxime; Cephalosporins; Cost-Benefit Analysis; Fe

1999
Oral versus initial intravenous therapy for urinary tract infections in young febrile children.
    Pediatrics, 1999, Volume: 104, Issue:1 Pt 1

    Topics: Acute Disease; Administration, Oral; Cefixime; Cefotaxime; Cephalosporins; Cost-Benefit Analysis; Fe

1999
Short term oral cefixime therapy for treatment of bacterial conjunctivitis.
    The Pediatric infectious disease journal, 2001, Volume: 20, Issue:11

    Topics: Acute Disease; Administration, Oral; Administration, Topical; Anti-Bacterial Agents; Bacitracin; Cef

2001
Short-term effectiveness of ceftriaxone single dose in the initial treatment of acute uncomplicated pyelonephritis in women. A randomised controlled trial.
    Emergency medicine journal : EMJ, 2002, Volume: 19, Issue:1

    Topics: Acute Disease; Adult; Cefixime; Ceftriaxone; Cephalosporins; Female; Humans; Middle Aged; Prospectiv

2002
Single-dose treatment of female acute uncomplicated cystitis.
    Infection, 1992, Volume: 20 Suppl 3

    Topics: Acute Disease; Administration, Oral; Anti-Infective Agents; Cefixime; Cefotaxime; Clinical Protocols

1992
[Clinical evaluation of usefulness of cefixime (200 mg administered once daily) in the treatment of acute uncomplicated cystitis].
    Hinyokika kiyo. Acta urologica Japonica, 1992, Volume: 38, Issue:11

    Topics: Acute Disease; Administration, Oral; Adult; Aged; Cefixime; Cefotaxime; Cystitis; Drug Administratio

1992
Comparison of cefprozil with other antibiotic regimens in the treatment of children with acute otitis media.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 1992, Volume: 14 Suppl 2

    Topics: Acute Disease; Amoxicillin; Amoxicillin-Potassium Clavulanate Combination; Anti-Infective Agents; Ce

1992
Single dose oral administration of cefixime 400mg in the treatment of acute uncomplicated cystitis and gonorrhoea.
    Drugs, 1991, Volume: 42 Suppl 4

    Topics: Acute Disease; Administration, Oral; Cefixime; Cefotaxime; Cystitis; Double-Blind Method; Female; Go

1991
Clinical efficacy and tolerability of cefixime in the treatment of acute sinusitis.
    Drugs, 1991, Volume: 42 Suppl 4

    Topics: Acute Disease; Adult; Aged; Cefixime; Cefotaxime; Drug Tolerance; Female; Humans; Male; Middle Aged;

1991
Cefixime vs amoxicillin in the treatment of acute otitis media in infants and children.
    Drugs, 1991, Volume: 42 Suppl 4

    Topics: Acute Disease; Amoxicillin; Cefixime; Cefotaxime; Child; Child, Preschool; Female; Humans; Infant; I

1991
Efficacy and tolerability of cefixime in otitis media. A multicentre study in over 25,000 children.
    Drugs, 1991, Volume: 42 Suppl 4

    Topics: Acute Disease; Cefixime; Cefotaxime; Child; Child, Preschool; Drug Tolerance; Female; Humans; Infant

1991
Measuring the comparative efficacy of antibacterial agents for acute otitis media: the "Pollyanna phenomenon".
    The Journal of pediatrics, 1992, Volume: 120, Issue:1

    Topics: Acute Disease; Amoxicillin; Ampicillin; Anti-Bacterial Agents; beta-Lactamase Inhibitors; Cefaclor;

1992
Bacteriology of acute otitis media: a new perspective.
    The Journal of pediatrics, 1992, Volume: 120, Issue:1

    Topics: Acute Disease; Adolescent; Amoxicillin; Amoxicillin-Potassium Clavulanate Combination; Bacteria; Bac

1992
Cefixime compared with amoxicillin for treatment of acute otitis media.
    The Journal of pediatrics, 1991, Volume: 119, Issue:1 Pt 1

    Topics: Acute Disease; Adolescent; Amoxicillin; Bacterial Infections; Cefixime; Cefotaxime; Child; Child, Pr

1991
Double-blind comparison of cefixime and cefaclor in the treatment of acute otitis media in children.
    Scandinavian journal of infectious diseases, 1991, Volume: 23, Issue:4

    Topics: Acute Disease; Anti-Bacterial Agents; Cefaclor; Cefixime; Cefotaxime; Child; Child, Preschool; Diarr

1991
[Effectiveness and tolerance of cefixime in the treatment of acute pyelonephritis].
    Infection, 1990, Volume: 18 Suppl 3

    Topics: Acute Disease; Adult; Aged; Aged, 80 and over; Anti-Infective Agents, Urinary; Body Temperature; Cef

1990
Randomized comparative study of cefixime versus cephalexin in acute bacterial exacerbations of chronic bronchitis.
    Antimicrobial agents and chemotherapy, 1990, Volume: 34, Issue:6

    Topics: Acute Disease; Bronchitis; Cefixime; Cefotaxime; Cephalexin; Chronic Disease; Gram-Negative Bacteria

1990
Respiratory viruses interfere with bacteriologic response to antibiotic in children with acute otitis media.
    The Journal of infectious diseases, 1990, Volume: 162, Issue:2

    Topics: Acute Disease; Amoxicillin; Anti-Bacterial Agents; Bacterial Infections; Cefixime; Cefotaxime; Child

1990
[Efficacy and tolerability of cefixime in lower respiratory tract infections in adults. French multicentric study].
    Presse medicale (Paris, France : 1983), 1989, Oct-11, Volume: 18, Issue:32

    Topics: Acute Disease; Adolescent; Adult; Aged; Aged, 80 and over; Cefixime; Cefotaxime; Clinical Trials as

1989
[Clinical evaluation of cefixime in the treatment of acute uncomplicated cystitis].
    Hinyokika kiyo. Acta urologica Japonica, 1989, Volume: 35, Issue:6

    Topics: Acute Disease; Bacterial Infections; Cefixime; Cefotaxime; Clinical Trials as Topic; Cystitis; Femal

1989
A general practice comparative study of a new third-generation oral cephalosporin, cefixime, with amoxycillin in the treatment of acute paediatric otitis media.
    The British journal of clinical practice, 1989, Volume: 43, Issue:4

    Topics: Acute Disease; Adolescent; Amoxicillin; Cefixime; Cefotaxime; Child; Child, Preschool; Family Practi

1989
A double-blind, multicenter, comparative study of the safety and efficacy of cefixime versus amoxicillin in the treatment of acute urinary tract infections in adult patients.
    The American journal of medicine, 1988, Sep-16, Volume: 85, Issue:3A

    Topics: Acute Disease; Adolescent; Adult; Aged; Amoxicillin; Cefixime; Cefotaxime; Clinical Trials as Topic;

1988
[A parallel comparative double blind study of cefixime with cefaclor in the treatment of acute suppurative otitis media in children].
    The Japanese journal of antibiotics, 1987, Volume: 40, Issue:1

    Topics: Acute Disease; Age Factors; Cefaclor; Cefixime; Cefotaxime; Cephalexin; Child; Child, Preschool; Cli

1987
[A parallel comparative double blind study of cefixime with cefroxadine in the treatment of acute lacunar tonsillitis].
    The Japanese journal of antibiotics, 1987, Volume: 40, Issue:1

    Topics: Acute Disease; Cefixime; Cefotaxime; Cephalosporins; Cephradine; Clinical Trials as Topic; Double-Bl

1987
Randomized, open label, multicenter trial of cefixime compared with amoxicillin for treatment of acute otitis media with effusion.
    The Pediatric infectious disease journal, 1987, Volume: 6, Issue:10

    Topics: Acute Disease; Amoxicillin; Cefixime; Cefotaxime; Child; Child, Preschool; Clinical Trials as Topic;

1987
Cefixime vs. cefaclor in the treatment of acute otitis media in infants and children.
    The Pediatric infectious disease journal, 1987, Volume: 6, Issue:10

    Topics: Acute Disease; Cefaclor; Cefixime; Cefotaxime; Cephalexin; Child; Child, Preschool; Female; Humans;

1987

Other Studies

21 other studies available for cefixime and Acute Disease

ArticleYear
Cefixime versus amoxicillin in the treatment of acute otitis media in infants and children.
    Journal of chemotherapy (Florence, Italy), 1989, Volume: 1, Issue:4 Suppl

    Topics: Acute Disease; Amoxicillin; Cefixime; Child; Child, Preschool; Controlled Clinical Trials as Topic;

1989
[Management of acute pyelonephritis in patients older than 3 months: survey conducted in 39 paediatric emergency departments of the Ile de France Region in 2004].
    Archives de pediatrie : organe officiel de la Societe francaise de pediatrie, 2006, Volume: 13, Issue:3

    Topics: Acute Disease; Administration, Oral; Adolescent; Age Factors; Anti-Bacterial Agents; Cefaclor; Cefix

2006
Acute septic arthritis: remember gonorrhea.
    Rheumatology international, 2008, Volume: 29, Issue:1

    Topics: Acute Disease; Anti-Bacterial Agents; Arthritis, Infectious; Cefixime; Ceftriaxone; Gonorrhea; Human

2008
An experimental study of cefixime in the treatment of Streptococcus pneumoniae otitis media.
    International journal of pediatric otorhinolaryngology, 1994, Volume: 29, Issue:1

    Topics: Acoustic Impedance Tests; Acute Disease; Ampicillin; Animals; Anti-Infective Agents; Cefixime; Cefot

1994
Cefixime therapy for otitis media.
    The Pediatric infectious disease journal, 1993, Volume: 12, Issue:8

    Topics: Acute Disease; Amoxicillin; Anti-Infective Agents; Cefixime; Cefotaxime; Child; Chronic Disease; Hum

1993
Efficacy of ceftibuten for acute otitis media caused by Hemophilus influenzae: an animal study.
    The Annals of otology, rhinology, and laryngology, 1993, Volume: 102, Issue:3 Pt 1

    Topics: Acute Disease; Ampicillin; Animals; Anti-Bacterial Agents; Cefixime; Cefotaxime; Ceftibuten; Cephalo

1993
A comparison of immunomagnetic separation and direct culture for the isolation of verocytotoxin-producing Escherichia coli O157 from cases of bloody diarrhoea, non-bloody diarrhoea and asymptomatic contacts.
    Journal of medical microbiology, 1996, Volume: 44, Issue:4

    Topics: Acute Disease; Animals; Anti-Bacterial Agents; Bacterial Toxins; Bacteriophage Typing; Cefixime; Cef

1996
Middle ear effusion concentrations of cefixime during acute otitis media with effusion and otitis media with effusion.
    The Pediatric infectious disease journal, 1997, Volume: 16, Issue:8

    Topics: Acute Disease; Cefixime; Cefotaxime; Cephalosporins; Child, Preschool; Ear, Middle; Humans; Infant;

1997
Cost-effectiveness of management strategies for acute urethritis in the developing world.
    Tropical medicine & international health : TM & IH, 2000, Volume: 5, Issue:9

    Topics: Acute Disease; Anti-Bacterial Agents; Anti-Infective Agents; Cefixime; Cost-Benefit Analysis; Decisi

2000
Effect of blood contamination on the interpretation of antibiotic concentrations in middle ear fluid.
    The Pediatric infectious disease journal, 1992, Volume: 11, Issue:3

    Topics: Acute Disease; Blood; Cefixime; Cefotaxime; Child, Preschool; Humans; Infant; Otitis Media, Suppurat

1992
Third-generation cephalosporins in the treatment of acute pneumococcal otitis media. An animal study.
    Archives of otolaryngology--head & neck surgery, 1992, Volume: 118, Issue:1

    Topics: Acoustic Impedance Tests; Acute Disease; Ampicillin; Animals; Cefixime; Cefotaxime; Ceftibuten; Ceph

1992
[Epidemiology, bacteriology and clinical experience with cefixime in the treatment of acute infantile otitis media].
    Anales espanoles de pediatria, 1991, Volume: 35 Suppl 46

    Topics: Acute Disease; Anti-Infective Agents; Cefixime; Cefotaxime; Child; Child, Preschool; Humans; Infant;

1991
[Cefixime therapy in sinusitis].
    Infection, 1990, Volume: 18 Suppl 3

    Topics: Acute Disease; Adult; Aged; Anti-Infective Agents; Cefixime; Cefotaxime; Chronic Disease; Drug Admin

1990
[Cefixime therapy in patients with proven gonorrhea].
    Infection, 1990, Volume: 18 Suppl 3

    Topics: Acute Disease; Adult; Anti-Infective Agents; Cefixime; Cefotaxime; Drug Tolerance; Gonorrhea; Humans

1990
[Clinical studies of cefixime in pediatric field].
    The Japanese journal of antibiotics, 1986, Volume: 39, Issue:4

    Topics: Acute Disease; Adolescent; Cefixime; Cefotaxime; Chemical and Drug Induced Liver Injury; Child; Chil

1986
Bacteriologic and clinical efficacy of cefixime compared with amoxicillin in acute otitis media.
    The Pediatric infectious disease journal, 1987, Volume: 6, Issue:10

    Topics: Acute Disease; Amoxicillin; Bacteria; Cefixime; Cefotaxime; Humans; Microbial Sensitivity Tests; Oti

1987
[Fundamental and clinical studies on cefixime in the pediatric field].
    The Japanese journal of antibiotics, 1986, Volume: 39, Issue:4

    Topics: Acute Disease; Bacteria; Bacterial Infections; Cefixime; Cefotaxime; Child; Child, Preschool; Female

1986
[Clinical experience with cefixime in the pediatric infections].
    The Japanese journal of antibiotics, 1986, Volume: 39, Issue:4

    Topics: Acute Disease; Adolescent; Bronchitis; Cefixime; Cefotaxime; Child; Child, Preschool; Female; Half-L

1986
[Clinical experience with cefixime in the pediatric field].
    The Japanese journal of antibiotics, 1986, Volume: 39, Issue:4

    Topics: Acute Disease; Adolescent; Bacterial Infections; Bronchopneumonia; Cefixime; Cefotaxime; Child; Chil

1986
[Fundamental and clinical studies on cefixime in pediatric field].
    The Japanese journal of antibiotics, 1986, Volume: 39, Issue:4

    Topics: Acute Disease; Bacterial Infections; Cefixime; Cefotaxime; Child; Child, Preschool; Enteritis; Femal

1986
[Pharmacokinetics and clinical effects of cefixime in pediatrics].
    The Japanese journal of antibiotics, 1986, Volume: 39, Issue:4

    Topics: Acute Disease; Adolescent; Bacterial Infections; Bronchitis; Cefixime; Cefotaxime; Child; Child, Pre

1986