cefepime and Eye-Diseases

cefepime has been researched along with Eye-Diseases* in 1 studies

Other Studies

1 other study(ies) available for cefepime and Eye-Diseases

Article	Year
Multistrain comparison of three antimicrobial prophylaxis regimens in experimental postoperative Pseudomonas endophthalmitis. American journal of ophthalmology, 1985, Sep-15, Volume: 100, Issue:3 We compared subconjunctivally administered ceftazidime and BMY 28142, two third-generation cephalosporins, to a regimen of gentamicin and cefazolin for their ability to prevent experimental Pseudomonas postoperative endophthalmitis in rabbits. After extracapsular lens extraction, an inoculum of Pseudomonas was injected into the vitreous; one of the three antimicrobial regimens was then administered subconjunctivally. All 25 eyes treated with gentamicin and cefazolin become infected (P = 1). Two of 25 eyes treated with BMY 28142 became infected (P less than .001). None of the 25 eyes treated with ceftazidime became infected (P less than .001). Topics: Animals; Anti-Bacterial Agents; Cefazolin; Cefepime; Ceftazidime; Cephalosporins; Drug Combinations; Drug Evaluation, Preclinical; Eye Diseases; Gentamicins; Inflammation; Postoperative Period; Pseudomonas Infections; Rabbits	1985

Article

Year

Multistrain comparison of three antimicrobial prophylaxis regimens in experimental postoperative Pseudomonas endophthalmitis.

American journal of ophthalmology, 1985, Sep-15, Volume: 100, Issue:3

We compared subconjunctivally administered ceftazidime and BMY 28142, two third-generation cephalosporins, to a regimen of gentamicin and cefazolin for their ability to prevent experimental Pseudomonas postoperative endophthalmitis in rabbits. After extracapsular lens extraction, an inoculum of Pseudomonas was injected into the vitreous; one of the three antimicrobial regimens was then administered subconjunctivally. All 25 eyes treated with gentamicin and cefazolin become infected (P = 1). Two of 25 eyes treated with BMY 28142 became infected (P less than .001). None of the 25 eyes treated with ceftazidime became infected (P less than .001).

Topics: Animals; Anti-Bacterial Agents; Cefazolin; Cefepime; Ceftazidime; Cephalosporins; Drug Combinations; Drug Evaluation, Preclinical; Eye Diseases; Gentamicins; Inflammation; Postoperative Period; Pseudomonas Infections; Rabbits

1985