cefdinir and Gastrointestinal-Hemorrhage

Cefdinir is a third-generation oral cephalosporin used frequently in the pediatric population. The most common side effects of cefdinir are diarrhea, nausea and dyspepsia. The side effect of turning the stool color to red and giving a bloody appearance, which is alarming for both families and physicians, is very rare. In this case report, we discussed 4 cases who referred to the emergency department with bloody stool due to the use of cefdinir. The important conclusion to be drawn from this case report is to know the rare side effects of commonly used drugs such as cefdinir. This will save time and resources and prevent unnecessary interventions on the patient.

Topics: Cefdinir; Cephalosporins; Child; Gastrointestinal Hemorrhage; Humans

Topics: Anti-Bacterial Agents; Cefdinir; Cephalosporins; Gastrointestinal Hemorrhage; Humans

Topics: Anti-Bacterial Agents; Cefdinir; Cephalosporins; Diagnosis, Differential; Gastrointestinal Hemorrhage; Humans; Infant; Male; Mexico; Otitis Media; Travel

Topics: Anti-Bacterial Agents; Cefdinir; Cephalosporins; Child, Preschool; Diagnosis, Differential; Diarrhea, Infantile; Drug Interactions; Female; Food Coloring Agents; Gastrointestinal Hemorrhage; Humans; Infant; Intussusception; Iron; Male

We describe nine children with antibiotic-associated hemorrhagic colitis without Clostridium difficile toxin. The onset was usually sudden, with severe hematochezia and abdominal cramps. The illness quickly resolved and required no specific treatment except discontinuation of the implicated antibiotic. Early proctosigmoidoscopy was a useful diagnostic adjunct. It appears that antibiotic-associated hemorrhagic colitis is a distinct entity rather than a variant of antibiotic-associated colitis in children.

Topics: Adolescent; Amoxicillin; Ampicillin; Anti-Bacterial Agents; Cefdinir; Cephalosporins; Child; Child, Preschool; Colitis; Enterocolitis, Pseudomembranous; Female; Gastrointestinal Hemorrhage; Humans; Male; Retrospective Studies; Sulbactam