cdp 840 has been researched along with Asthma in 8 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (50.00) | 18.2507 |
| 2000's | 4 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Alexander, RP; Allen, RA; Barnes, D; Boyce, B; Boyd, EC; Brown, JA; Cannell, A; Eaton, MA; Gozzard, N; Head, JC; Higgs, G; Hughes, B; Hutchinson, B; Leonard, J; Mason, B; Millican, A; Morphy, R; Perry, M; Porter, JR; Reuberson, JT; Taylor, RJ; Turner, P; Wales, M; Warrellow, GJ; Zomaya, A | 1 |
| Jabaris, SS; Kodimuthali, A; Pal, M | 1 |
| Blake, SM; el-Hashim, A; Gozzard, N; Herd, CM; Higgs, GA; Holbrook, M; Hughes, B; Page, CP | 1 |
| Alexander, R; Allen, R; Blease, K; Bloxham, D; Boyd, E; Catterall, C; Eaton, M; Gozzard, N; Head, J; Higgs, G; Holbrook, M; Howat, D; Hughes, B; Hughes, P; James, T; Kingaby, R; Lisle, H; Lumb, S; Merriman, M; Owens, R; Perry, M; Russell, A; Smith, B; Wales, M; Warrellow, G | 1 |
| Costello, J; Harbinson, PL; Hawksworth, R; Heath, P; Holgate, ST; Kilfeather, S; Lee, TH; MacLeod, D; O'Toole, S; Page, CP; Sullivan, PJ | 1 |
| Jones, TR; Macdonald, D; McAuliffe, M; McFarlane, CS; Piechuta, H; Rodger, IW | 1 |
| Egging, EA; Gullikson, GW; Hammerbeck, DM; Hupperts, AM; Johnson, DD; McGurran, SM; Radziszewski, PL | 1 |
| Allen, JM; Banner, KH; Doherty, A; Jones, NA; Landells, LJ; O'Connor, BJ; Page, CP; Spina, D; Szilagy, CM | 1 |
1 review(s) available for cdp 840 and Asthma
| Article | Year |
|---|---|
Recent advances on phosphodiesterase 4 inhibitors for the treatment of asthma and chronic obstructive pulmonary disease.
Topics: Asthma; Humans; Phosphodiesterase 4 Inhibitors; Phosphodiesterase Inhibitors; Pulmonary Disease, Chronic Obstructive | 2008 |
1 trial(s) available for cdp 840 and Asthma
| Article | Year |
|---|---|
The effect of a novel orally active selective PDE4 isoenzyme inhibitor (CDP840) on allergen-induced responses in asthmatic subjects.
Topics: Adolescent; Adult; Allergens; Asthma; Bronchi; Bronchial Hyperreactivity; Bronchial Provocation Tests; Double-Blind Method; Forced Expiratory Volume; Histamine; Humans; Phosphodiesterase Inhibitors; Pyridines; Skin Tests | 1997 |
6 other study(ies) available for cdp 840 and Asthma
| Article | Year |
|---|---|
CDP840. A prototype of a novel class of orally active anti-inflammatory phosphodiesterase 4 inhibitors.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Asthma; Bronchoconstriction; Cyclic Nucleotide Phosphodiesterases, Type 4; Dose-Response Relationship, Drug; Ferrets; Guinea Pigs; Humans; Inhibitory Concentration 50; Phosphodiesterase Inhibitors; Pyridines; Rats; Rolipram; Saccharomyces cerevisiae; Structure-Activity Relationship; Tumor Necrosis Factor-alpha | 2002 |
Effect of the glucocorticosteroid budesonide and a novel phosphodiesterase type 4 inhibitor CDP840 on antigen-induced airway responses in neonatally immunised rabbits.
Topics: Administration, Inhalation; Airway Resistance; Analysis of Variance; Animals; Anti-Inflammatory Agents; Asthma; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Bronchoconstriction; Budesonide; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Histamine Antagonists; Humans; In Vitro Techniques; Lung; Male; Neutrophils; Phosphodiesterase Inhibitors; Pregnenediones; Pyridines; Rabbits; Respiratory Hypersensitivity; Trachea | 1996 |
The inhibition of antigen-induced eosinophilia and bronchoconstriction by CDP840, a novel stereo-selective inhibitor of phosphodiesterase type 4.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Airway Resistance; Analysis of Variance; Animals; Asthma; Benzamides; Bronchoconstriction; Cyclic Nucleotide Phosphodiesterases, Type 4; Disease Models, Animal; Dose-Response Relationship, Drug; Eosinophilia; Guinea Pigs; Humans; Interleukin-5; Isoenzymes; Lung; Male; Neutrophils; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Pyridines; Pyrrolidinones; Rabbits; Rats; Rolipram | 1996 |
Effects of a selective phosphodiesterase IV inhibitor (CDP-840) in a leukotriene-dependent non-human primate model of allergic asthma.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Antigens, Helminth; Ascaris; Asthma; Bronchoconstriction; Cyclic Nucleotide Phosphodiesterases, Type 4; Leukotrienes; Male; Phosphodiesterase Inhibitors; Pyridines; Saimiri; Skin Tests; Time Factors | 1998 |
Effects of several glucocorticosteroids and PDE4 inhibitors on increases in total lung eosinophil peroxidase (EPO) levels following either systemic or intratracheal administration in sephadex- or ovalbumin-induced inflammatory models.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Androstadienes; Animals; Asthma; Beclomethasone; Benzamides; Budesonide; Cyclic Nucleotide Phosphodiesterases, Type 4; Dexamethasone; Dextrans; Disease Models, Animal; Enzyme Inhibitors; Eosinophil Peroxidase; Eosinophils; Fluticasone; Glucocorticoids; Guinea Pigs; Inflammation; Lung; Male; Ovalbumin; Peroxidases; Pyridines; Rats; Rats, Sprague-Dawley; Rolipram | 2000 |
Identification and quantification of phosphodiesterase 4 subtypes in CD4 and CD8 lymphocytes from healthy and asthmatic subjects.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adolescent; Adult; Allergens; Asthma; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Cell Division; Cyclic Nucleotide Phosphodiesterases, Type 3; Cyclic Nucleotide Phosphodiesterases, Type 4; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Female; Gene Expression Regulation, Enzymologic; Humans; Isoenzymes; Leukocytes, Mononuclear; Male; Phosphodiesterase Inhibitors; Phytohemagglutinins; Pyridines; Reverse Transcriptase Polymerase Chain Reaction; RNA; Rolipram; Theophylline | 2001 |