cd 437 has been researched along with Acute Promyelocytic Leukemia in 5 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (60.00) | 18.2507 |
| 2000's | 2 (40.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Barbarroja, N; Buendía, P; Dorado, G; López-Pedrera, C; Torres, A; Velasco, F | 1 |
| Adamo, S; Avvisati, G; Benedetti, L; Diverio, D; Gambacorti-Passerini, C; Grignani, F; Jetten, AM; Levin, AA; Lo Coco, F; Nervi, C; Pelicci, PG; Scicchitano, BM | 1 |
| Bergamaschi, D; Bresciani, F; Garattini, E; Gianní, M; Mologni, L; Ponzanelli, I; Rambaldi, A; Reichert, U; Sardiello, G; Terao, M | 1 |
| de Thé, H; Giannì, M | 1 |
| Erba, E; Garattini, E; Garofalo, A; Giannì, M; Giavazzi, R; Nicoletti, I; Ponzanelli, I; Rambaldi, A; Reichert, U; Terao, M | 1 |
5 other study(ies) available for cd 437 and Acute Promyelocytic Leukemia
| Article | Year |
|---|---|
Promyelocytic leukemia retinoid signaling targets regulate apoptosis,tissue factor and thrombomodulin expression.
Topics: Apoptosis; Benzoates; Cell Differentiation; Cell Line, Tumor; Flavonoids; Gene Expression; Humans; Leukemia, Promyelocytic, Acute; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 3; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Retinoids; Tetrahydronaphthalenes; Thrombomodulin; Thromboplastin | 2004 |
Retinoid-induced differentiation of acute promyelocytic leukemia involves PML-RARalpha-mediated increase of type II transglutaminase.
Topics: Apoptosis; Benzoates; CD18 Antigens; Cell Differentiation; Chromosomes, Human, Pair 15; Chromosomes, Human, Pair 17; Cytosol; Drug Resistance, Neoplasm; Enzyme Induction; Fenretinide; Gene Expression Regulation, Leukemic; Humans; Isoenzymes; Leukemia, Promyelocytic, Acute; Neoplasm Proteins; Neoplastic Stem Cells; Oncogene Proteins, Fusion; Protein Multimerization; Receptors, Retinoic Acid; Retinoids; Signal Transduction; Tetrahydronaphthalenes; Transglutaminases; Translocation, Genetic; Tretinoin; Tumor Cells, Cultured | 1996 |
The novel synthetic retinoid 6-[3-adamantyl-4-hydroxyphenyl]-2-naphthalene carboxylic acid (CD437) causes apoptosis in acute promyelocytic leukemia cells through rapid activation of caspases.
Topics: Amino Acid Chloromethyl Ketones; Antineoplastic Agents; Apoptosis; Caspases; Cytochrome c Group; Cytosol; Enzyme Activation; Enzyme Inhibitors; Humans; Leukemia, Promyelocytic, Acute; Mitochondria; Neoplasm Proteins; Receptors, Retinoic Acid; Retinoic Acid Receptor alpha; Retinoic Acid Receptor gamma; Retinoids; S Phase; Signal Transduction; Tretinoin | 1999 |
In acute promyelocytic leukemia NB4 cells, the synthetic retinoid CD437 induces contemporaneously apoptosis, a caspase-3-mediated degradation of PML/RARalpha protein and the PML retargeting on PML-nuclear bodies.
Topics: Antineoplastic Agents; Apoptosis; Arsenic Trioxide; Arsenicals; Caspase 3; Caspases; Cell Line; Humans; Leukemia, Promyelocytic, Acute; Neoplasm Proteins; Nuclear Proteins; Oxides; Promyelocytic Leukemia Protein; Proto-Oncogene Proteins c-bcl-2; Reactive Oxygen Species; Receptors, Retinoic Acid; Retinoic Acid Receptor alpha; Retinoids; Transcription Factors; Tumor Suppressor Proteins | 1999 |
Isolation and characterization of an acute promyelocytic leukemia cell line selectively resistant to the novel antileukemic and apoptogenic retinoid 6-[3-adamantyl-4-hydroxyphenyl]-2-naphthalene carboxylic acid.
Topics: Animals; Antineoplastic Agents; Apoptosis; Drug Resistance, Neoplasm; Humans; Leukemia, Promyelocytic, Acute; Mice; Mice, SCID; Retinoids; Tumor Cells, Cultured | 2000 |