cathepsin-g has been researched along with Urinary-Bladder-Neoplasms* in 1 studies
1 other study(ies) available for cathepsin-g and Urinary-Bladder-Neoplasms
| Article | Year |
|---|---|
Identification of an immune-related long non-coding RNA signature and nomogram as prognostic target for muscle-invasive bladder cancer.
To identify an immune-related prognostic signature based on long non-coding RNAs (lncRNAs) and find immunotherapeutic targets for bladder urothelial carcinoma, we downloaded RNA-sequencing data from The Cancer Genome Atlas (TCGA) dataset. Functional enrichment analysis demonstrated bladder urothelial carcinoma was related to immune-related functions. We obtained 332 immune-related genes and 262 lncRNAs targeting immune-related genes. We constructed a signature based on eight lncRNAs in training cohort. Patients were classified as high-risk and low-risk according to signature risk score. High-risk patients had poor overall survival compared with low-risk patients ( Topics: Aged; Biomarkers, Tumor; Carcinoma, Transitional Cell; Cathepsin G; Chemokine CXCL12; Datasets as Topic; DNA Ligase ATP; Female; Follow-Up Studies; Gene Expression Regulation, Neoplastic; Humans; Immunohistochemistry; Kaplan-Meier Estimate; Male; Middle Aged; Muscles; Neoplasm Invasiveness; Nomograms; Predictive Value of Tests; Risk Factors; RNA-Seq; RNA, Long Noncoding; ROC Curve; T-Box Domain Proteins; Transcriptome; Urinary Bladder; Urinary Bladder Neoplasms | 2020 |