catechol has been researched along with Parkinson Disease in 15 studies
Parkinson Disease: A progressive, degenerative neurologic disease characterized by a TREMOR that is maximal at rest, retropulsion (i.e. a tendency to fall backwards), rigidity, stooped posture, slowness of voluntary movements, and a masklike facial expression. Pathologic features include loss of melanin containing neurons in the substantia nigra and other pigmented nuclei of the brainstem. LEWY BODIES are present in the substantia nigra and locus coeruleus but may also be found in a related condition (LEWY BODY DISEASE, DIFFUSE) characterized by dementia in combination with varying degrees of parkinsonism. (Adams et al., Principles of Neurology, 6th ed, p1059, pp1067-75)
| Excerpt | Relevance | Reference |
|---|---|---|
| "A full understanding of Parkinson's Disease etiopathogenesis and of the causes of the preferential vulnerability of nigrostriatal dopaminergic neurons is still an unsolved puzzle." | 2.61 | Impaired dopamine metabolism in Parkinson's disease pathogenesis. ( Boassa, D; Bubacco, L; Masato, A; Plotegher, N, 2019) |
| "Although the cause of Parkinson's disease is unknown, oxidative stress has been implicated in its pathogenesis." | 2.40 | [Oxidative stress and the brain]. ( Tanaka, M, 1997) |
| "Pakinson diseases, schizophrenia, and breast cancer." | 1.43 | [The relationship between catechol O-methyltransferase and diseases]. ( Bi, XL; Dou, TY; Ge, GB; Hou, J; Ma, H; Qian, XK; Xia, YL; Yang, L, 2016) |
| "Pure autonomic failure (PAF) and Parkinson's disease (PD) share several clinical laboratory abnormalities; however, PAF is not associated with parkinsonism." | 1.35 | Central dopamine deficiency in pure autonomic failure. ( Bernson, M; Carmona, G; Goldstein, DS; Holmes, C; Imrich, R; Mizrahi, N; Sato, T; Sharabi, Y; Vortmeyer, AO, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (6.67) | 18.2507 |
| 2000's | 2 (13.33) | 29.6817 |
| 2010's | 10 (66.67) | 24.3611 |
| 2020's | 2 (13.33) | 2.80 |
| Authors | Studies |
|---|---|
| Chavarria, D | 1 |
| Benfeito, S | 1 |
| Soares, P | 1 |
| Lima, C | 1 |
| Garrido, J | 1 |
| Serrão, P | 1 |
| Soares-da-Silva, P | 1 |
| Remião, F | 1 |
| Oliveira, PJ | 1 |
| Borges, F | 1 |
| Masato, A | 1 |
| Plotegher, N | 1 |
| Boassa, D | 1 |
| Bubacco, L | 1 |
| Goldstein, DS | 2 |
| Qian, XK | 1 |
| Xia, YL | 1 |
| Dou, TY | 1 |
| Hou, J | 1 |
| Ma, H | 1 |
| Ge, GB | 1 |
| Yang, L | 1 |
| Bi, XL | 1 |
| Feng, JH | 1 |
| Hu, XL | 1 |
| Lv, XY | 1 |
| Wang, BL | 1 |
| Lin, J | 1 |
| Zhang, XQ | 1 |
| Ye, WC | 1 |
| Xiong, F | 1 |
| Wang, H | 1 |
| Soloway, AH | 1 |
| Soloway, PD | 1 |
| Warner, VD | 1 |
| Contu, VR | 1 |
| Kotake, Y | 1 |
| Toyama, T | 1 |
| Okuda, K | 1 |
| Miyara, M | 1 |
| Sakamoto, S | 1 |
| Samizo, S | 1 |
| Sanoh, S | 1 |
| Kumagai, Y | 1 |
| Ohta, S | 1 |
| Dell'Acqua, S | 1 |
| Pirota, V | 1 |
| Anzani, C | 1 |
| Rocco, MM | 1 |
| Nicolis, S | 1 |
| Valensin, D | 1 |
| Monzani, E | 1 |
| Casella, L | 1 |
| Kimos, M | 1 |
| Burton, M | 1 |
| Urbain, D | 1 |
| Caudron, D | 1 |
| Martini, M | 1 |
| Famelart, M | 1 |
| Gillard, M | 1 |
| Barrow, J | 1 |
| Wood, M | 1 |
| Mazzulli, JR | 1 |
| Burbulla, LF | 1 |
| Krainc, D | 1 |
| Ischiropoulos, H | 1 |
| Stern, G | 1 |
| Subramaniam, V | 1 |
| Griffith, L | 1 |
| Haes, AJ | 1 |
| Hasegawa, T | 1 |
| Matsuzaki-Kobayashi, M | 1 |
| Takeda, A | 1 |
| Sugeno, N | 1 |
| Kikuchi, A | 1 |
| Furukawa, K | 1 |
| Perry, G | 1 |
| Smith, MA | 1 |
| Itoyama, Y | 1 |
| Holmes, C | 1 |
| Sato, T | 1 |
| Bernson, M | 1 |
| Mizrahi, N | 1 |
| Imrich, R | 1 |
| Carmona, G | 1 |
| Sharabi, Y | 1 |
| Vortmeyer, AO | 1 |
| Tanaka, M | 1 |
4 reviews available for catechol and Parkinson Disease
| Article | Year |
|---|---|
Impaired dopamine metabolism in Parkinson's disease pathogenesis.
Topics: Animals; Brain; Catechols; Dopamine; Dopaminergic Neurons; Humans; Oxidative Stress; Parkinson Disea | 2019 |
The Catecholaldehyde Hypothesis for the Pathogenesis of Catecholaminergic Neurodegeneration: What We Know and What We Do Not Know.
Topics: Aldehyde Dehydrogenase; Aldehydes; alpha-Synuclein; Animals; Catechols; Dopamine; Humans; Monoamine | 2021 |
Why catechol?
Topics: Animals; Catechols; History, 19th Century; History, 20th Century; Humans; Parkinson Disease | 2011 |
[Oxidative stress and the brain].
Topics: Animals; Catechols; Dopamine; Ferritins; Humans; Iron; Lipid Peroxidation; Microglia; Oxidative Stre | 1997 |
11 other studies available for catechol and Parkinson Disease
| Article | Year |
|---|---|
Boosting caffeic acid performance as antioxidant and monoamine oxidase B/catechol-O-methyltransferase inhibitor.
Topics: Amides; Antioxidants; Catechol O-Methyltransferase; Catechol O-Methyltransferase Inhibitors; Catecho | 2022 |
[The relationship between catechol O-methyltransferase and diseases].
Topics: Breast Neoplasms; Catechol O-Methyltransferase; Catechols; Dopamine; Epinephrine; Estradiol; Humans; | 2016 |
Synthesis and biological evaluation of clovamide analogues with catechol functionality as potent Parkinson's disease agents in vitro and in vivo.
Topics: Apoptosis; Catechols; Cell Line, Tumor; Dose-Response Relationship, Drug; Humans; Molecular Structur | 2019 |
Possible chemical initiators of cognitive dysfunction in phenylketonuria, Parkinson's disease and Alzheimer's disease.
Topics: Alzheimer Disease; Catechols; Cognition Disorders; Humans; Metabolic Networks and Pathways; Methioni | 2013 |
Endogenous neurotoxic dopamine derivative covalently binds to Parkinson's disease-associated ubiquitin C-terminal hydrolase L1 and alters its structure and function.
Topics: Animals; Blotting, Western; Catechols; Cell Line, Tumor; Cell Survival; Dopamine; Electrophoresis, A | 2014 |
Reactivity of copper-α-synuclein peptide complexes relevant to Parkinson's disease.
Topics: alpha-Synuclein; Amino Acid Sequence; Catechols; Copper; Humans; Molecular Sequence Data; Oxidation- | 2015 |
Development of an HTRF Assay for the Detection and Characterization of Inhibitors of Catechol-O-Methyltransferase.
Topics: Benzophenones; Catechol O-Methyltransferase; Catechol O-Methyltransferase Inhibitors; Catechols; Hig | 2016 |
Detection of Free and Protein-Bound ortho-Quinones by Near-Infrared Fluorescence.
Topics: Catechols; Dopamine; Dopaminergic Neurons; Fluorescence; Humans; Induced Pluripotent Stem Cells; Inf | 2016 |
Varying nanoparticle pseudostationary phase plug length during capillary electrophoresis.
Topics: Catechols; Dopamine; Electrophoresis, Capillary; Epinephrine; Fatty Acids; Humans; Levodopa; Nanopar | 2011 |
Alpha-synuclein facilitates the toxicity of oxidized catechol metabolites: implications for selective neurodegeneration in Parkinson's disease.
Topics: alpha-Synuclein; Apoptosis; Catechols; Cells, Cultured; Comet Assay; DNA Damage; Enzyme Activation; | 2006 |
Central dopamine deficiency in pure autonomic failure.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aged; Autonomic Nervous System Diseases; Brain; Catechols; Dihydroxy | 2008 |