catechol has been researched along with Leukemia, Myeloid, Acute in 2 studies
Leukemia, Myeloid, Acute: Clonal expansion of myeloid blasts in bone marrow, blood, and other tissue. Myeloid leukemias develop from changes in cells that normally produce NEUTROPHILS; BASOPHILS; EOSINOPHILS; and MONOCYTES.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Chronic exposure to high concentrations of benzene is associated with an increased incidence of myelodysplastic syndrome (MDS) and acute myelogenous leukemia (AML)." | 3.70 | The benzene metabolites hydroquinone and catechol act in synergy to induce dose-dependent hypoploidy and -5q31 in a human cell line. ( Irons, RD; Stillman, WS; Varella-Garcia, M, 1999) |
| "Etoposide is a topoisomerase II poison that is used to treat a variety of human cancers." | 1.37 | Etoposide quinone is a redox-dependent topoisomerase II poison. ( Deweese, JE; Jacob, DA; Mercer, SL; Osheroff, N, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Jacob, DA | 1 |
| Mercer, SL | 1 |
| Osheroff, N | 1 |
| Deweese, JE | 1 |
| Stillman, WS | 1 |
| Varella-Garcia, M | 1 |
| Irons, RD | 1 |
2 other studies available for catechol and Leukemia, Myeloid, Acute
| Article | Year |
|---|---|
Etoposide quinone is a redox-dependent topoisomerase II poison.
Topics: Antigens, Neoplasm; Benzoquinones; Catechols; Dithiothreitol; DNA Adducts; DNA Damage; DNA Topoisome | 2011 |
The benzene metabolites hydroquinone and catechol act in synergy to induce dose-dependent hypoploidy and -5q31 in a human cell line.
Topics: Benzene; Catechols; Cell Transformation, Neoplastic; Chromosome Deletion; Chromosomes, Human, Pair 5 | 1999 |