Page last updated: 2024-10-16

catechol and Alzheimer Disease

catechol has been researched along with Alzheimer Disease in 12 studies

Alzheimer Disease: A degenerative disease of the BRAIN characterized by the insidious onset of DEMENTIA. Impairment of MEMORY, judgment, attention span, and problem solving skills are followed by severe APRAXIAS and a global loss of cognitive abilities. The condition primarily occurs after age 60, and is marked pathologically by severe cortical atrophy and the triad of SENILE PLAQUES; NEUROFIBRILLARY TANGLES; and NEUROPIL THREADS. (From Adams et al., Principles of Neurology, 6th ed, pp1049-57)

Research Excerpts

ExcerptRelevanceReference
"As for Alzheimer's disease, we analyzed the effect of coffee on amyloid β (Aβ) production in human neuronal SH-SY5Y cells."2.66[Molecular Basis of Preventive Effects of Habitual Coffee Intake against Chronic Diseases]. ( Tamura, H, 2020)
"The number of patients with Alzheimer's disease (AD) and type 2 diabetes (T2D) is increasing rapidly, and thus more research has been focused on the relationship between these two age-related chronic diseases."1.56Inhibitory activities of phenylpropanoids from Lycopus lucidus on amyloid aggregation related to Alzheimer's disease and type 2 diabetes. ( Murata, T; Shigemori, H; Sun, J, 2020)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (8.33)18.2507
2000's1 (8.33)29.6817
2010's6 (50.00)24.3611
2020's4 (33.33)2.80

Authors

AuthorsStudies
Velander, P1
Wu, L1
Hildreth, SB1
Vogelaar, NJ1
Mukhopadhyay, B1
Helm, RF1
Zhang, S1
Xu, B1
Sun, J1
Murata, T1
Shigemori, H4
Tamura, H2
Tsunoda, T1
Takase, M2
Fukuyama, K1
Kakio, S1
Nakazawa, Y1
Kobata, K1
Funakoshi-Tago, M1
Suzuki, T1
Jiang, G1
Aihara, Y1
Kurisu, M1
Miyamae, Y1
Murakami, K1
Han, J1
Isoda, H1
Irie, K1
Soloway, AH1
Soloway, PD1
Warner, VD1
Soeda, Y1
Yoshikawa, M1
Almeida, OF1
Sumioka, A1
Maeda, S1
Osada, H1
Kondoh, Y1
Saito, A1
Miyasaka, T1
Kimura, T1
Suzuki, M1
Koyama, H1
Yoshiike, Y1
Sugimoto, H1
Ihara, Y1
Takashima, A1
Sugimoto, K1
Tamura, K1
Ohta, N1
Tohda, C1
Toyooka, N1
Nemoto, H1
Matsuya, Y1
da Silva, GF1
Ming, LJ1
Fornstedt, B1

Reviews

2 reviews available for catechol and Alzheimer Disease

ArticleYear
[Molecular Basis of Preventive Effects of Habitual Coffee Intake against Chronic Diseases].
    Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 2020, Volume: 140, Issue:11

    Topics: Adipogenesis; Alzheimer Disease; Amyloid beta-Peptides; Amyloid Precursor Protein Secretases; Animal

2020
Role of catechol autooxidation in the degeneration of dopamine neurons.
    Acta neurologica Scandinavica. Supplementum, 1990, Volume: 129

    Topics: Aged; Alzheimer Disease; Animals; Brain; Catechols; Dementia; Dopamine; Guinea Pigs; Humans; Nerve D

1990

Other Studies

10 other studies available for catechol and Alzheimer Disease

ArticleYear
Catechol-containing compounds are a broad class of protein aggregation inhibitors: Redox state is a key determinant of the inhibitory activities.
    Pharmacological research, 2022, Volume: 184

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloidogenic Proteins; Animals; Anthraquinones; Catechols

2022
Inhibitory activities of phenylpropanoids from Lycopus lucidus on amyloid aggregation related to Alzheimer's disease and type 2 diabetes.
    Journal of natural medicines, 2020, Volume: 74, Issue:3

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Catechols; Diabetes Mellitus, Type 2; Humans; Islet Amyloi

2020
Structure-activity relationship of clovamide and its related compounds for the inhibition of amyloid β aggregation.
    Bioorganic & medicinal chemistry, 2018, 07-23, Volume: 26, Issue:12

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Cacao; Catechols; Cinnamates; Dihydroxyphenylalanine; Huma

2018
Roasted Coffee Reduces β-Amyloid Production by Increasing Proteasomal β-Secretase Degradation in Human Neuroblastoma SH-SY5Y Cells.
    Molecular nutrition & food research, 2018, Volume: 62, Issue:21

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid Precursor Protein Secretases; Aspartic Acid Endope

2018
Inhibitory activities of kukoamines A and B from Lycii Cortex on amyloid aggregation related to Alzheimer's disease and type 2 diabetes.
    Journal of natural medicines, 2020, Volume: 74, Issue:1

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Caffeic Acids; Catechols; Diabetes Mellitus, Type 2; Human

2020
Inhibition of amyloid β aggregation by acteoside, a phenylethanoid glycoside.
    Bioscience, biotechnology, and biochemistry, 2013, Volume: 77, Issue:6

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Catechols; Dose-Response Relationship, Drug; Glucosides; H

2013
Possible chemical initiators of cognitive dysfunction in phenylketonuria, Parkinson's disease and Alzheimer's disease.
    Medical hypotheses, 2013, Volume: 81, Issue:4

    Topics: Alzheimer Disease; Catechols; Cognition Disorders; Humans; Metabolic Networks and Pathways; Methioni

2013
Toxic tau oligomer formation blocked by capping of cysteine residues with 1,2-dihydroxybenzene groups.
    Nature communications, 2015, Dec-16, Volume: 6

    Topics: Adrenergic beta-Agonists; Alzheimer Disease; Animals; Behavior, Animal; Blotting, Western; Brain; Ca

2015
Synthesis of dihydrofuran-fused perhydrophenanthrenes having a phenolic hydroxyl group as a novel anti-Alzheimer's disease agent.
    Bioorganic & medicinal chemistry letters, 2012, Jan-01, Volume: 22, Issue:1

    Topics: Alzheimer Disease; Catechols; Chemistry, Pharmaceutical; Drug Design; Humans; Models, Chemical; Mole

2012
Metallo-ROS in Alzheimer's disease: oxidation of neurotransmitters by CuII-beta-amyloid and neuropathology of the disease.
    Angewandte Chemie (International ed. in English), 2007, Volume: 46, Issue:18

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Catecholamines; Catechols; Cations, Divalent; Copper; Dopa

2007