catechin has been researched along with Skin Neoplasms in 60 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 1 (1.67) | 18.7374 |
1990's | 14 (23.33) | 18.2507 |
2000's | 20 (33.33) | 29.6817 |
2010's | 22 (36.67) | 24.3611 |
2020's | 3 (5.00) | 2.80 |
Authors | Studies |
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Brebi, P; Buchegger, K; Ili, C; Kurachi, C; León, D; Mora-Lagos, B; Riquelme, I; Roa, JC; Schafer, F; Silva, R; Viscarra, T; Zanella, L | 1 |
Lee, J; Li, X; Wang, Y; Xu, A; Xu, P; Zhao, Y | 1 |
Cleutjens, J; Hillen, LM; Kelleners-Smeets, NWJ; Kessels, J; Mosterd, K; Nelemans, P; Voeten, L | 1 |
Meeran, SM; Penta, D; Somashekar, BS | 1 |
Badhan, RKS; Lowry, D; Marwah, M; Perrie, Y | 1 |
El-Kayal, M; Elkheshen, S; Mortada, N; Nasr, M | 1 |
Ashby, CR; Chauhan, H; Heenatigala Palliyage, G; Singh, S; Tiwari, AK | 1 |
Donejko, M; Galicka, E; Niczyporuk, M; Przylipiak, A | 1 |
Fujiki, H; Sueoka, E; Suganuma, M | 1 |
Boakye, CH; Doddapaneni, R; Godugu, C; Katiyar, SK; Patel, AR; Safe, S; Shah, PP; Singh, M | 1 |
Katiyar, SK; Singh, T | 1 |
Tong, LX; Young, LC | 1 |
Meyer, T; Stockfleth, E | 1 |
Aggarwal, V; Monga, J; Nongalleima, K; Sharma, M; Suthar, SK | 1 |
Balasubramanian, S; Eckert, RL; Han, B; Scharadin, TM; Xu, W | 1 |
Chen, X; Huang, Z; Lei, Z; Luo, Z; Peng, C; Su, J; Zeng, W; Zhang, J; Zhang, X; Zhou, Y | 1 |
Li, J; Lin, Y; Liu, H; Wu, Y | 1 |
Adhikary, G; Balasubramanian, S; Eckert, RL; Gopalakrishnan, R; Lee, K; Rorke, EA | 1 |
Chang, EJ; Fujii, H; Hwang, DM; Kundu, JK; Lee, JC; Shin, YK; Sun, B; Surh, YJ | 1 |
Baechler, BJ; Frestedt, JL; Jones, L; Nita, F | 1 |
Goto, K; Kawata, K; Kitanaka, S; Yasukawa, K | 1 |
Katiyar, SK; Nichols, JA | 1 |
Adhikary, G; Balasubramanian, S; Eckert, RL | 1 |
Jiang, P; Li, J; Li, Y; Lu, J; Shen, Q; Tian, F; Zhang, L | 1 |
Chatterjee, A; Moulik, S; Sen, T; Sil, H | 1 |
Katiyar, SK; Nandakumar, V; Vaid, M | 1 |
Dev Sharma, P; Manon, B; Sharma, M; Vir Singh, T; Vyas, S | 1 |
Balasubramanian, S; Chew, YC; Choudhury, SR; Eckert, RL; Han, B; Marquez, VE | 1 |
Dunn, JH; Ellis, LZ; Fujita, M; Liu, W; Luo, Y; Okamoto, M; Qu, D | 1 |
Fujiki, H; Imai, K; Katsuta, N; Kuramochi, H; Nakayama, T; Suganuma, M; Takahashi, A; Watanabe, T | 1 |
Cheng, KH; Chiou, YS; Ho, CT; Pan, MH; Sang, S; Wang, YJ | 1 |
Conney, AH; Huang, MT; Liao, J; Lou, YR; Lu, YP; Peng, QY; Xie, JG; Yang, CS | 1 |
Cho, KH; Chung, JH; Eun, HC; Han, JH; Hwang, EJ; Kim, KH; Seo, JY; Youn, JI | 1 |
Barr, RJ; Carpenter, PM; Hite, P; Li, KT; Linden, KG; McLaren, CE; Meyskens, FL; Sun, JD; Viner, JL | 1 |
Hara, Y; Kumagai, A; Kuwajima, H; Mukainaka, T; Nagaoka, Y; Nishino, H; Obayashi, T; Terashima, Y; Tokuda, H; Uesato, S | 1 |
Athar, M; Gilmour, SK; Hayes, CS; Kim, A; Paul, B | 1 |
Campbell, S; Clifford, T; Curnow, A; Gould, D; Morley, N; Salter, L | 1 |
Fang, JY; Huang, YL; Hung, CF; Hwang, TL | 1 |
Cascante, M; Centelles, JJ; Jimenez, A; Julià, L; Lozano, C; Torres, JL | 1 |
Elmets, CA; Katiyar, SK; Mantena, SK; Meeran, SM | 1 |
Cheng, TO | 1 |
Elangovan, V; Govindasamy, S; Sekar, N | 1 |
Frenkel, K; Furuya, H; Nishiwaki, S; Nishiwaki-Matsushima, R; Okabe, S; Suganuma, M; Troll, W; Verma, AK; Yatsunami, J; Yoshizawa, S | 1 |
Nair, SC; Panikkar, B; Panikkar, KR; Varghese, CD | 1 |
Alberts, DS; Dorr, R; Dvorakova, K; Gensler, HL; Timmermann, BN; Valcic, S; Wächter, GA | 1 |
Yoshizawa, S | 1 |
Agarwal, R; Katiyar, SK; Mohan, RR; Mukhtar, H | 1 |
al-Rawi, M; Edelstein, D; Khafif, A; Sacks, PG; Schantz, SP | 1 |
Bair, WB; Barthelman, M; Bowden, GT; Chen, W; Dong, Z; Stickland, KK; Timmermann, BN; Valcic, S | 1 |
Agarwal, R; Chen, Y; Wang, J; Zhao, J | 1 |
Agarwal, C; Agarwal, R; Bhatia, N | 1 |
Blanchard, J; Liederer, BM; Proniuk, S | 1 |
Hatano, T; Ito, H; Itoh, Y; Kobayashi, E; Kubo, N; Li, SH; Nishino, H; Shimura, S; Sugita, D; Tokuda, H; Yoshida, T | 1 |
Diamandis, EP; Goldberg, DM; Grass, L; Josephy, PD; Soleas, GJ | 1 |
Agarwal, R; Bhatia, AK; Katiyar, SK; Mukhtar, H; Wang, ZY | 1 |
Fujiki, H; Horiuchi, T; Nishiwaki, S; Nishiwaki-Matsushima, R; Okabe, S; Okuda, T; Suganuma, M; Sugimura, T; Yatsunami, J; Yoshizawa, S | 1 |
Chang, R; Conney, AH; Ferraro, T; Ho, CT; Huang, MT; Ma, W; Reuhl, KR; Wang, ZY; Yang, CS | 1 |
Agarwal, R; Katiyar, SK; Mukhtar, H; Zaidi, SI | 1 |
Fujiki, H; Kobayashi, M; Okuda, T; Ootsuyama, A; Suganuma, M; Sugimura, T; Suguri, H; Takagi, K; Tanooka, H; Yoshizawa, S | 1 |
12 review(s) available for catechin and Skin Neoplasms
Article | Year |
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Epigenetics of skin cancer: Interventions by selected bioactive phytochemicals.
Topics: Anticarcinogenic Agents; Catechin; DNA Methylation; Epigenesis, Genetic; Histones; Humans; Isothiocyanates; Melanoma; Phytochemicals; Skin Neoplasms; Sulfoxides; Transcriptional Activation | 2018 |
Pharmaceutical Topical Delivery of Poorly Soluble Polyphenols: Potential Role in Prevention and Treatment of Melanoma.
Topics: Animals; Antioxidants; Biological Availability; Catechin; Curcumin; Drug Delivery Systems; Humans; Melanoma; Nanoparticles; Polyphenols; Quercetin; Resveratrol; Skin Neoplasms; Solubility | 2019 |
[Anti-cancer properties epigallocatechin-gallate contained in green tea].
Topics: Animals; Anticarcinogenic Agents; Antioxidants; Breast Neoplasms; Catechin; Cell Transformation, Neoplastic; Female; Gastrointestinal Neoplasms; Humans; Male; Neoplasms; Skin Neoplasms; Tea | 2013 |
Tumor promoters: from chemicals to inflammatory proteins.
Topics: Animals; Anticarcinogenic Agents; Carcinogens; Catechin; Gastrointestinal Neoplasms; Helicobacter Infections; Humans; Inflammation; Inflammation Mediators; Neoplasms, Experimental; Okadaic Acid; Organ Specificity; Skin Neoplasms | 2013 |
Nutrition: the future of melanoma prevention?
Topics: Antioxidants; Carotenoids; Catechin; Diet; Grape Seed Extract; Humans; Lycopene; Melanoma; Nutrition Policy; Proanthocyanidins; Resveratrol; Selenium; Skin Neoplasms; Stilbenes; Vitamin D; Vitamin E | 2014 |
Sinecatechins (Polyphenon E) ointment for treatment of external genital warts and possible future indications.
Topics: Antioxidants; Antiviral Agents; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Catechin; Chemoprevention; Condylomata Acuminata; Humans; Keratosis, Actinic; Ointments; Skin Neoplasms | 2014 |
The Bmi-1 polycomb group gene in skin cancer: regulation of function by (-)-epigallocatechin-3-gallate.
Topics: Animals; Anticarcinogenic Agents; Catechin; Diet; Epidermis; Epigenesis, Genetic; Humans; Mice; Nuclear Proteins; Polycomb Repressive Complex 1; Proto-Oncogene Proteins; Repressor Proteins; Skin Neoplasms; Tea | 2008 |
Skin photoprotection by natural polyphenols: anti-inflammatory, antioxidant and DNA repair mechanisms.
Topics: Anti-Inflammatory Agents; Antioxidants; Catechin; Dermatitis; DNA Damage; DNA Repair; Flavonoids; Humans; Neoplasms, Radiation-Induced; Phenols; Polyphenols; Skin; Skin Neoplasms; Sunscreening Agents; Tea; Ultraviolet Rays | 2010 |
Chemoprevention of nonmelanoma skin cancer: experience with a polyphenol from green tea.
Topics: Antineoplastic Agents, Phytogenic; Catechin; Chemoprevention; Clinical Trials as Topic; Flavonoids; Humans; Phenols; Polyphenols; Skin Neoplasms; Tea; Ultraviolet Rays | 2003 |
Mechanisms of action of new antitumor promoters.
Topics: Animals; Anticarcinogenic Agents; Antineoplastic Agents; Carcinogens; Catechin; Diterpenes; Humans; Mice; Sesquiterpenes; Skin Neoplasms | 1993 |
Anticarcinogenic effects of (-)-epigallocatechin gallate.
Topics: Animals; Anticarcinogenic Agents; Catechin; Hydrolyzable Tannins; Male; Mice; Mice, Inbred C57BL; Skin; Skin Neoplasms; Tannins; Tea; Tetradecanoylphorbol Acetate | 1992 |
Betel-quid and areca-nut chewing.
Topics: Adolescent; Adult; Aged; Animals; Areca; Asia; Calcium; Calcium Compounds; Catechin; Child; Child, Preschool; Congenital Abnormalities; Cricetinae; Cricetulus; Cross-Sectional Studies; Female; Global Health; Habits; Humans; Infant; Infant, Newborn; Leukoplakia; Lichen Planus; Male; Mesocricetus; Mice; Middle Aged; Mouth Diseases; Mouth Neoplasms; Mutagenicity Tests; Oxides; Pacific Islands; Papua New Guinea; Plant Extracts; Plants, Medicinal; Precancerous Conditions; Pregnancy; Prospective Studies; Rats; Skin Neoplasms; Stomach Neoplasms; Tooth Diseases | 1985 |
1 trial(s) available for catechin and Skin Neoplasms
Article | Year |
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Topical Sinecatechins, 10%, Ointment for Superficial Basal Cell Carcinoma: A Randomized Clinical Trial.
Topics: Administration, Topical; Biopsy; Camellia sinensis; Carcinoma, Basal Cell; Catechin; Dose-Response Relationship, Drug; Double-Blind Method; Female; Follow-Up Studies; Humans; Male; Ointments; Retrospective Studies; Skin; Skin Neoplasms; Treatment Outcome | 2017 |
47 other study(ies) available for catechin and Skin Neoplasms
Article | Year |
---|---|
Epigallocatechin Gallate Enhances MAL-PDT Cytotoxic Effect on PDT-Resistant Skin Cancer Squamous Cells.
Topics: Aminolevulinic Acid; Anticarcinogenic Agents; Carcinoma, Squamous Cell; Catechin; Cell Death; Cell Hypoxia; Cell Line, Tumor; Cell Proliferation; Cell Survival; Combined Modality Therapy; Ferrochelatase; Heat-Shock Proteins; Humans; Membrane Transport Proteins; Molecular Chaperones; Photochemotherapy; Photosensitizing Agents; Protoporphyrins; Reactive Oxygen Species; Skin Neoplasms; Stress, Physiological; Superoxide Dismutase; Survivin; Symporters | 2020 |
Potential effect of EGCG on the anti-tumor efficacy of metformin in melanoma cells.
Topics: Animals; Antineoplastic Agents; Apoptosis; Catechin; Cell Line, Tumor; Cell Movement; Cell Nucleus; Cell Proliferation; Cell Survival; Cytokines; Cytoplasm; Inflammation; Melanoma; Melanoma, Experimental; Metformin; Mice; NF-kappa B p50 Subunit; Oxidative Stress; Phosphorylation; Skin Neoplasms; Spectrum Analysis, Raman; STAT3 Transcription Factor | 2021 |
Intracellular uptake of EGCG-loaded deformable controlled release liposomes for skin cancer.
Topics: Antineoplastic Agents; Catechin; Cell Survival; Cells, Cultured; Delayed-Action Preparations; Dose-Response Relationship, Drug; Drug Carriers; Drug Delivery Systems; Drug Liberation; Drug Screening Assays, Antitumor; Humans; Liposomes; Molecular Structure; Particle Size; Polysorbates; Skin Absorption; Skin Neoplasms; Structure-Activity Relationship; Surface Properties; Surface-Active Agents | 2020 |
Colloidal (-)-epigallocatechin-3-gallate vesicular systems for prevention and treatment of skin cancer: A comprehensive experimental study with preclinical investigation.
Topics: Animals; Catechin; Cell Line, Tumor; Colloids; Drug Carriers; Humans; Lecithins; Male; Mice, Inbred BALB C; Mice, Nude; Polysorbates; Skin Neoplasms | 2019 |
Chemoprevention of skin cancer with 1,1-Bis (3'-indolyl)-1-(aromatic) methane analog through induction of the orphan nuclear receptor, NR4A2 (Nurr1).
Topics: 8-Hydroxy-2'-Deoxyguanosine; Apoptosis; Blotting, Western; Catechin; Cell Line, Tumor; Cell Survival; Cells, Cultured; Chemoprevention; Deoxyguanosine; Dose-Response Relationship, Drug; Humans; Immunohistochemistry; Indoles; Inhibitory Concentration 50; Keratinocytes; Nuclear Receptor Subfamily 4, Group A, Member 2; Oxidative Stress; Reactive Oxygen Species; Skin Neoplasms; Ultraviolet Rays | 2013 |
Green tea polyphenol, (-)-epigallocatechin-3-gallate, induces toxicity in human skin cancer cells by targeting β-catenin signaling.
Topics: Anticarcinogenic Agents; beta Catenin; Catechin; Cell Line, Tumor; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Drug Delivery Systems; Humans; Polyphenols; Signal Transduction; Skin Neoplasms; Tea | 2013 |
Topical (+)-catechin emulsified gel prevents DMBA/TPA-induced squamous cell carcinoma of the skin by modulating antioxidants and inflammatory biomarkers in BALB/c mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Acacia; Administration, Topical; Animals; Antioxidants; Biomarkers; Carcinoma, Squamous Cell; Catechin; Dinoprostone; Drug Evaluation, Preclinical; Emulsions; Humans; Inflammation Mediators; Interleukin-1beta; Interleukin-6; Male; Mice; Mice, Inbred BALB C; Nitric Oxide Synthase Type II; Plant Extracts; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 2014 |
The Bmi-1 helix-turn and ring finger domains are required for Bmi-1 antagonism of (-) epigallocatechin-3-gallate suppression of skin cancer cell survival.
Topics: Anticarcinogenic Agents; Apoptosis; Catechin; Cell Line, Tumor; Cell Survival; Gene Expression Regulation; Humans; Mutation; Polycomb Repressive Complex 1; Polycomb-Group Proteins; RING Finger Domains; Skin Neoplasms | 2015 |
Epigallocatechin-3-gallate(EGCG) suppresses melanoma cell growth and metastasis by targeting TRAF6 activity.
Topics: Animals; Antineoplastic Agents, Phytogenic; Catechin; Cell Line, Tumor; Cell Movement; Cell Proliferation; Enzyme Inhibitors; Gene Expression Regulation, Neoplastic; HEK293 Cells; Humans; Intracellular Signaling Peptides and Proteins; Lung Neoplasms; MAP Kinase Kinase Kinases; Melanoma; Mice, Inbred BALB C; Molecular Docking Simulation; Neoplasm Invasiveness; NF-kappa B; NF-KappaB Inhibitor alpha; Phosphorylation; Protein Binding; Protein Conformation; Signal Transduction; Skin Neoplasms; Structure-Activity Relationship; TNF Receptor-Associated Factor 6; Transfection; Tumor Burden; Ubiquitin-Conjugating Enzymes; Ubiquitin-Protein Ligases; Ubiquitination | 2016 |
Inhibition of invasion and up-regulation of E-cadherin expression in human malignant melanoma cell line A375 by (-)-epigallocatechin-3-gallate.
Topics: Blotting, Western; Cadherins; Catechin; Cell Adhesion; Cell Line, Tumor; Gene Expression Regulation, Neoplastic; Humans; Melanoma; Neoplasm Invasiveness; Neoplasm Metastasis; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Skin Neoplasms; Time Factors; Up-Regulation | 2008 |
Inhibitory effects of oligonol on phorbol ester-induced tumor promotion and COX-2 expression in mouse skin: NF-kappaB and C/EBP as potential targets.
Topics: Animals; Catechin; CCAAT-Enhancer-Binding Proteins; Cells, Cultured; Cyclooxygenase 2; Immunohistochemistry; Mice; NF-kappa B; Phenols; Phorbol Esters; Skin; Skin Neoplasms | 2009 |
A novel liquid multi-phytonutrient supplement demonstrates DNA-protective effects.
Topics: Antimutagenic Agents; Antioxidants; Catechin; Cell Line; Cell Survival; Dietary Supplements; DNA Damage; Dose-Response Relationship, Radiation; Drug Combinations; Fruit; Humans; Magnoliopsida; Neoplasms, Radiation-Induced; Phytotherapy; Plant Extracts; Radiation-Protective Agents; Skin Neoplasms; Ultraviolet Rays; Vegetables | 2009 |
Anti-tumor promoters phenolics and triterpenoid from Hippophae rhamnoides.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anti-Inflammatory Agents; Antineoplastic Agents, Phytogenic; Catechin; Female; Hippophae; Inflammation; Mice; Mice, Inbred ICR; Phytotherapy; Plant Extracts; Plant Stems; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2009 |
The Bmi-1 polycomb protein antagonizes the (-)-epigallocatechin-3-gallate-dependent suppression of skin cancer cell survival.
Topics: Anticarcinogenic Agents; Apoptosis; Carcinoma, Squamous Cell; Catechin; Cell Count; Cell Cycle Proteins; Cell Line, Transformed; Cell Line, Tumor; Culture Media, Serum-Free; DNA Replication; DNA-Binding Proteins; Enhancer of Zeste Homolog 2 Protein; Epigenesis, Genetic; Gene Knockdown Techniques; Genetic Vectors; Humans; Keratinocytes; Neoplasm Proteins; Nuclear Proteins; Polycomb Repressive Complex 1; Polycomb Repressive Complex 2; Polycomb-Group Proteins; Proto-Oncogene Proteins; Recombinant Fusion Proteins; Repressor Proteins; Skin Neoplasms; Transcription Factors | 2010 |
EGCG enhances TRAIL-mediated apoptosis in human melanoma A375 cell line.
Topics: Antineoplastic Agents; Apoptosis; Caspase 3; Caspase 8; Catechin; Cell Line, Tumor; Drug Synergism; Humans; Melanoma; Receptors, TNF-Related Apoptosis-Inducing Ligand; Skin Neoplasms; TNF-Related Apoptosis-Inducing Ligand | 2009 |
Black tea polyphenol (theaflavin) downregulates MMP-2 in human melanoma cell line A375 by involving multiple regulatory molecules.
Topics: Animals; Antineoplastic Agents; Biflavonoids; Catechin; Cell Adhesion; Cell Line, Tumor; Cell Survival; Down-Regulation; Extracellular Matrix; Female; Gene Expression Regulation, Neoplastic; Genes, Regulator; Humans; Ligands; Matrix Metalloproteinase 2; Matrix Metalloproteinase Inhibitors; Melanoma; Mice; Plant Extracts; RNA, Messenger; Skin Neoplasms; Tea; Tissue Inhibitor of Metalloproteinase-2 | 2010 |
(-)-Epigallocatechin-3-gallate reactivates silenced tumor suppressor genes, Cip1/p21 and p16INK4a, by reducing DNA methylation and increasing histones acetylation in human skin cancer cells.
Topics: Acetylation; Anticarcinogenic Agents; Azacitidine; Catechin; Cell Line, Tumor; Cyclin-Dependent Kinase Inhibitor p21; Decitabine; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Genes, p16; Histone Deacetylases; Histones; Humans; Hydroxamic Acids; Skin Neoplasms; Transcriptional Activation | 2011 |
Potential O-acyl-substituted (-)-Epicatechin gallate prodrugs as inhibitors of DMBA/TPA-induced squamous cell carcinoma of skin in Swiss albino mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents, Phytogenic; Carcinoma, Squamous Cell; Catechin; Female; Humans; Hydrolysis; Mice; Prodrugs; Skin; Skin Neoplasms; Solubility; Tea; Tetradecanoylphorbol Acetate | 2011 |
(-)-Epigallocatechin-3-gallate and DZNep reduce polycomb protein level via a proteasome-dependent mechanism in skin cancer cells.
Topics: Acetylation; Adenosine; Anticarcinogenic Agents; Apoptosis; Blotting, Western; Carrier Proteins; Caspases; Catechin; Cell Cycle; Cell Proliferation; Cells, Cultured; DNA Methylation; DNA-Binding Proteins; Drug Synergism; Enhancer of Zeste Homolog 2 Protein; Histone Deacetylase 1; Histones; Humans; Keratinocytes; Membrane Potential, Mitochondrial; Neoplasm Proteins; Nuclear Proteins; Polycomb Repressive Complex 1; Polycomb Repressive Complex 2; Polycomb-Group Proteins; Proteasome Endopeptidase Complex; Proto-Oncogene Proteins; Repressor Proteins; Skin Neoplasms; Transcription Factors; Ubiquitination | 2011 |
Green tea polyphenol epigallocatechin-3-gallate suppresses melanoma growth by inhibiting inflammasome and IL-1β secretion.
Topics: Animals; Antineoplastic Agents; Camellia sinensis; Catechin; Cell Line, Tumor; Cell Proliferation; Female; Humans; Inflammation; Interleukin-1beta; Melanoma; Mice; Mice, Nude; Polyphenols; Skin Neoplasms | 2011 |
Higher cell stiffness indicating lower metastatic potential in B16 melanoma cell variants and in (-)-epigallocatechin gallate-treated cells.
Topics: Animals; Anticarcinogenic Agents; Catechin; Cell Movement; Elastic Modulus; Elasticity; Melanoma, Experimental; Mice; Microscopy, Atomic Force; Skin Neoplasms | 2012 |
Peracetylated (-)-epigallocatechin-3-gallate (AcEGCG) potently prevents skin carcinogenesis by suppressing the PKD1-dependent signaling pathway in CD34+ skin stem cells and skin tumors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Acetates; Animals; Antigens, CD34; Catechin; CCAAT-Enhancer-Binding Proteins; Cell Proliferation; Cell Transformation, Neoplastic; Chemoprevention; Cyclic AMP Response Element-Binding Protein; Cyclooxygenase 2; Extracellular Signal-Regulated MAP Kinases; Male; Mice; Mice, Inbred ICR; Mitogen-Activated Protein Kinase 8; Mitogen-Activated Protein Kinase 9; Mitotic Index; Nitric Oxide Synthase Type II; Ornithine Decarboxylase; p38 Mitogen-Activated Protein Kinases; Phosphatidylinositol 3-Kinase; Phosphorylation; Protein Kinase C; Proto-Oncogene Proteins c-akt; Skin Neoplasms; Stem Cells; Tetradecanoylphorbol Acetate; Vascular Endothelial Growth Factor A | 2013 |
Topical applications of caffeine or (-)-epigallocatechin gallate (EGCG) inhibit carcinogenesis and selectively increase apoptosis in UVB-induced skin tumors in mice.
Topics: Administration, Topical; Animals; Apoptosis; Bromodeoxyuridine; Caffeine; Caspase 3; Caspases; Catechin; Female; Mice; Mice, Hairless; Neoplasms, Radiation-Induced; Skin Neoplasms; Tea; Ultraviolet Rays | 2002 |
Dual mechanisms of green tea extract (EGCG)-induced cell survival in human epidermal keratinocytes.
Topics: Apoptosis; bcl-2-Associated X Protein; bcl-Associated Death Protein; Carcinoma, Squamous Cell; Carrier Proteins; Catechin; Cell Division; Cell Survival; Cells, Cultured; Epidermal Cells; Humans; Keratinocytes; Mitogen-Activated Protein Kinases; Models, Biological; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-bcl-2; Signal Transduction; Skin Neoplasms; Tumor Cells, Cultured | 2003 |
Tumor chemopreventive activity of 3-O-acylated (--)-epigallocatechins.
Topics: Acylation; Animals; Anticarcinogenic Agents; Catechin; Magnetic Resonance Spectroscopy; Mice; Papilloma; Skin Neoplasms; Spectrometry, Mass, Electrospray Ionization; Spectrophotometry, Infrared | 2003 |
Elevated polyamines lead to selective induction of apoptosis and inhibition of tumorigenesis by (-)-epigallocatechin-3-gallate (EGCG) in ODC/Ras transgenic mice.
Topics: Animals; Anticarcinogenic Agents; Apoptosis; Biogenic Polyamines; Catechin; Cell Proliferation; Cells, Cultured; Genes, ras; Immunoblotting; Immunohistochemistry; Keratinocytes; Mice; Mice, Transgenic; Ornithine Decarboxylase; ras Proteins; Skin Neoplasms | 2005 |
The green tea polyphenol (-)-epigallocatechin gallate and green tea can protect human cellular DNA from ultraviolet and visible radiation-induced damage.
Topics: Antimutagenic Agents; Antioxidants; Catechin; Cells, Cultured; Comet Assay; DNA Damage; Fibroblasts; Flavonoids; Humans; Molecular Structure; Phenols; Polyphenols; Radiation-Protective Agents; Skin Neoplasms; Statistics, Nonparametric; Tea; Ultraviolet Rays | 2005 |
Physicochemical characteristics and in vivo deposition of liposome-encapsulated tea catechins by topical and intratumor administrations.
Topics: Administration, Topical; Animals; Catechin; Deoxycholic Acid; Drug Evaluation, Preclinical; Drug Stability; Injections, Intralesional; Liposomes; Mice; Mice, Nude; Neoplasms, Experimental; Organophosphates; Skin; Skin Neoplasms; Tea | 2005 |
Effect of new antioxidant cysteinyl-flavanol conjugates on skin cancer cells.
Topics: Antineoplastic Agents, Phytogenic; Antioxidants; Apoptosis; Catechin; Cell Cycle; Cysteine; Electron Transport; Flavonoids; Free Radical Scavengers; Humans; Keratinocytes; Melanoma; Skin Neoplasms; Tumor Cells, Cultured; Vitis | 2005 |
(-)-Epigallocatechin-3-gallate prevents photocarcinogenesis in mice through interleukin-12-dependent DNA repair.
Topics: Animals; Anticarcinogenic Agents; Catechin; DNA Repair; Female; Interleukin-12; Male; Mice; Mice, Inbred C3H; Mice, Knockout; Neoplasms, Radiation-Induced; Recombinant Proteins; Skin; Skin Neoplasms; Ultraviolet Rays; Xeroderma Pigmentosum Group A Protein | 2006 |
Can green tea protect against not only sunburn but also melanoma?
Topics: Catechin; Melanoma; Nitric Oxide; Skin Neoplasms; Sunburn; Tea; Ultraviolet Rays | 2006 |
Chemopreventive potential of dietary bioflavonoids against 20-methylcholanthrene-induced tumorigenesis.
Topics: Animals; Catechin; Diet; Fibrosarcoma; Flavonoids; Incidence; Luteolin; Male; Methylcholanthrene; Mice; Mice, Inbred Strains; Quercetin; Rutin; Skin Neoplasms | 1994 |
Effect of asoka on the intracellular glutathione levels and skin tumour promotion in mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Catechin; Croton Oil; Drug Screening Assays, Antitumor; Fibrosarcoma; Glutathione Reductase; Glutathione Transferase; Male; Methylcholanthrene; Mice; Papilloma; Sarcoma 180; Skin Neoplasms | 1993 |
Prevention of photocarcinogenesis by topical administration of pure epigallocatechin gallate isolated from green tea.
Topics: Administration, Topical; Animals; Antigens, Neoplasm; Antineoplastic Agents; Catechin; Female; Immune Tolerance; Mice; Mice, Inbred BALB C; Skin Neoplasms; Tea; Ultraviolet Rays | 1996 |
[(-)-Epigallocatechin gallate, the main constituent of Japanese green tea, inhibits tumor promotion of okadaic acid].
Topics: Animals; Antineoplastic Agents; Binding Sites; Carcinogens; Catechin; Mice; Okadaic Acid; Skin Neoplasms; Tea | 1996 |
Protection against induction of mouse skin papillomas with low and high risk of conversion to malignancy by green tea polyphenols.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Antioxidants; Carcinoma, Squamous Cell; Catechin; Cocarcinogenesis; Disease Progression; Diterpenes; Flavonoids; Mice; Mice, Inbred SENCAR; Papilloma; Phenols; Plant Extracts; Polymers; Skin Neoplasms; Tea; Terpenes | 1997 |
Green tea regulates cell cycle progression in oral leukoplakia.
Topics: Anticarcinogenic Agents; Blotting, Western; Carcinoma, Squamous Cell; Catechin; Cell Division; Cell Transformation, Neoplastic; Cells, Cultured; Child, Preschool; Humans; Leukoplakia, Oral; Models, Biological; Mouth Mucosa; Phytotherapy; Sensitivity and Specificity; Skin Neoplasms; Tea | 1998 |
(-)-Epigallocatechin-3-gallate inhibition of ultraviolet B-induced AP-1 activity.
Topics: Animals; Anticarcinogenic Agents; Catechin; Cell Line; Humans; Keratinocytes; Mice; Mice, Transgenic; Sensitivity and Specificity; Skin Neoplasms; Tea; Transcription Factor AP-1; Ultraviolet Rays | 1998 |
Anti-tumor-promoting activity of a polyphenolic fraction isolated from grape seeds in the mouse skin two-stage initiation-promotion protocol and identification of procyanidin B5-3'-gallate as the most effective antioxidant constituent.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Acetone; Administration, Cutaneous; Animals; Anticarcinogenic Agents; Antioxidants; Ascorbic Acid; Biflavonoids; Catechin; Cocarcinogenesis; Epidermis; Female; Flavonoids; Lipid Peroxidation; Mice; Mice, Inbred SENCAR; Microsomes; Molecular Structure; Phenols; Plant Extracts; Polymers; Proanthocyanidins; Rosales; Seeds; Skin Neoplasms; Tetradecanoylphorbol Acetate; Vitamin E | 1999 |
Differential responses of skin cancer-chemopreventive agents silibinin, quercetin, and epigallocatechin 3-gallate on mitogenic signaling and cell cycle regulators in human epidermoid carcinoma A431 cells.
Topics: Adaptor Proteins, Signal Transducing; Adaptor Proteins, Vesicular Transport; Anticarcinogenic Agents; Apoptosis; Carcinoma, Squamous Cell; Catechin; CDC2-CDC28 Kinases; Cell Cycle; Cell Cycle Proteins; Cyclin D1; Cyclin-Dependent Kinase 2; Cyclin-Dependent Kinase 4; Cyclin-Dependent Kinase Inhibitor p21; Cyclin-Dependent Kinase Inhibitor p27; Cyclin-Dependent Kinases; Cyclins; Enzyme Inhibitors; ErbB Receptors; Humans; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Mitogens; Phosphorylation; Protein Serine-Threonine Kinases; Proteins; Proto-Oncogene Proteins; Quercetin; Shc Signaling Adaptor Proteins; Signal Transduction; Silymarin; Skin Neoplasms; Src Homology 2 Domain-Containing, Transforming Protein 1; Tumor Cells, Cultured; Tumor Suppressor Proteins | 2001 |
Preformulation study of epigallocatechin gallate, a promising antioxidant for topical skin cancer prevention.
Topics: Administration, Topical; Antineoplastic Agents, Phytogenic; Antioxidants; Catechin; Chemistry, Pharmaceutical; Drug Evaluation, Preclinical; Drug Stability; Ethylene Glycols; Glycerol; Osmolar Concentration; Skin Neoplasms; Solvents | 2002 |
Antitumor activity of compounds isolated from leaves of Eriobotrya japonica.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antigens, Viral; Antineoplastic Agents; Biflavonoids; Carcinogens; Catechin; Female; Glucosides; Herpesvirus 4, Human; Humans; Mice; Mice, Inbred ICR; Nasopharyngeal Neoplasms; Norisoprenoids; Peroxynitrous Acid; Plant Leaves; Proanthocyanidins; Rosaceae; Skin Neoplasms; Tea; Tetradecanoylphorbol Acetate; Virus Activation | 2002 |
A comparison of the anticarcinogenic properties of four red wine polyphenols.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents, Phytogenic; Catechin; Flavonoids; Gallic Acid; Mice; Phenols; Polymers; Quercetin; Resveratrol; Skin Neoplasms; Stilbenes; Tetradecanoylphorbol Acetate; Wine | 2002 |
(-)-Epigallocatechin-3-gallate in Camellia sinensis leaves from Himalayan region of Sikkim: inhibitory effects against biochemical events and tumor initiation in Sencar mouse skin.
Topics: Administration, Cutaneous; Animals; Antimutagenic Agents; Catechin; DNA; Enzyme Induction; Female; Masoprocol; Mice; Mice, Inbred Strains; Ornithine Decarboxylase; Sikkim; Skin Neoplasms; Tea; Tetradecanoylphorbol Acetate; Tritium | 1992 |
Inhibitory effect of green tea on the growth of established skin papillomas in mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Catechin; Drug Screening Assays, Antitumor; Female; Flavonoids; Injections, Intraperitoneal; Mice; Papilloma; Phenols; Plant Extracts; Polymers; Skin Neoplasms; Tea; Tetradecanoylphorbol Acetate | 1992 |
Inhibition of skin tumor promoter-caused induction of epidermal ornithine decarboxylase in SENCAR mice by polyphenolic fraction isolated from green tea and its individual epicatechin derivatives.
Topics: Animals; Catechin; Chromatography, High Pressure Liquid; Enzyme Induction; Female; Mice; Ornithine Decarboxylase Inhibitors; Plant Extracts; Skin; Skin Neoplasms; Tea; Tetradecanoylphorbol Acetate | 1992 |
New antitumor promoters: (-)-epigallocatechin gallate and sarcophytols A and B.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Catechin; Cnidaria; Cocarcinogenesis; Diterpenes; Female; Flavonoids; Lyngbya Toxins; Mammary Neoplasms, Experimental; Mice; Skin Neoplasms; Tea | 1990 |