catechin has been researched along with Lung Neoplasms in 129 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 18 (13.95) | 18.2507 |
| 2000's | 36 (27.91) | 29.6817 |
| 2010's | 63 (48.84) | 24.3611 |
| 2020's | 12 (9.30) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, F; Chen, N; Deng, X; Gu, Q; Li, Z; Wang, J | 1 |
| Armeni, T; Cianfruglia, L; Galeazzi, R; Laudadio, E; Minnelli, C; Mobbili, G | 1 |
| Datta, S; Sinha, D | 1 |
| Dai, W; Efferth, T; Guo, L; Shan, L; Xiao, X; Yan, B; Yuan, Q; Zhang, J; Zhou, L | 1 |
| Sheng, J; Sun, XL; Wang, LX; Wang, XJ; Wu, YL; Xiang, ZM; Xie, YR; Zhang, DY; Zhang, N; Zi, CT | 1 |
| Iida, K; Namiki, K; Rawangkan, A; Sakai, R; Sato, M; Suganuma, M; Wongsirisin, P; Yokoyama, S | 1 |
| Chen, BH; Hsieh, CH; Tsai, SY; Wang, CC; Wang, CY | 1 |
| Chandra, S; Joshi, T; Maiti, P; Nand, M; Ramakrishnan, MA | 1 |
| Chen, W; Chen, X; Lu, Y; Tu, G; Wu, L; Zhang, L; Zheng, D | 1 |
| Abrahamse, H; George, BP; Senapathy, GJ | 1 |
| Chen, L; Feng, Q; Jiang, P; Li, S; Mageed, F; Ren, J; Wu, X; Xu, C; Zeb, F; Zhang, P | 1 |
| An, H; Ma, B; Qu, C; Shi, S; Sun, F | 1 |
| Chen, A; Feng, Q; Jiang, P; Mariyam, Z; Ul Haq, I; Wu, X; Zhou, M | 1 |
| Cao, J; Chen, G; Jiao, Y; Wu, J; Xing, L; Xue, J; Yang, H; Yu, C; Zhang, Q; Zhang, S; Zhu, W | 1 |
| Honda, Y; Ichihara, E; Kiura, K; Kubo, T; Murakami, T; Ninomiya, T; Ochi, N; Takigawa, N; Tanimoto, M; Yamane, H; Yasugi, M | 1 |
| Atwi, D; Banerjee, P; Fried, A; Hussaini, R; Mukherjee, S; Pan, Q; Piao, L; Sampat, S; White, R | 1 |
| Dhatwalia, SK; Dhawan, DK; Kumar, M | 1 |
| Chang, MC; Chen, CA; Chen, YL; Cheng, WF; Chiang, YC; Lin, HW; Sun, NY; Sun, WZ | 1 |
| Ceballos, G; Cordero, P; Gutiérrez-Iglesias, G; Meaney, E; Nájera, N; Palma, I; Ramirez-Sanchez, I; Rubio-Gayosso, I; Varela-Castillo, O; Villarreal, F | 1 |
| Burlando, B; Martinotti, S; Ranzato, E | 2 |
| Chen, P; Gu, JJ; Li, Q; Qiao, KS; Sun, P | 1 |
| Chen, A; Chen, L; Feng, Q; Haq, IU; Jiang, P; Mariyam, Z; Wu, X; Xu, C; Zhou, M | 2 |
| Fujiki, H; Iida, K; Kobayashi, Y; Namiki, K; Rawangkan, A; Shimizu, Y; Suganuma, M; Wongsirisin, P | 1 |
| Hu, DL; Huang, YF; Wang, D; Wang, G; Yu, J; Zhang, LH; Zhou, HH | 1 |
| Bhardwaj, V; Mandal, AKA | 1 |
| Chen, G; Jia, L; Li, X; Meng, X; Xing, L; Zhao, H; Zhao, X; Zhu, W | 1 |
| Kępka, L; Rychter, A | 1 |
| Lu, QY; Lundmark, L; Mao, JT; Massie, L; Neis, P; Qualls, C; Xue, B; Zamora, FD | 1 |
| Chen, Z; Ma, G; Sun, H; Wang, X; Wei, X; Yang, J; Zhang, C | 1 |
| Butt, MS; Imran, A; Imran, M; Mubarak, MS; Ramadan, MF; Rauf, A; Xiao, H | 1 |
| Choi, HK; Choi, KC; Jeon, H; Jeong, MH; Ko, H; Lee, SW; Ryu, SH; So, Y; Yoon, HG | 1 |
| Chen, Q; Hong, C; Jiang, Z; Jin, L; Li, C; Liu, J; Ma, Y; Wang, D; Wang, L; Xu, Y; Yu, F | 1 |
| Biffo, S; Burlando, B; Gallo, S; Martinotti, S; Mutti, L; Ranzato, E; Russo, MV; Volta, V | 1 |
| Deng, PB; Hu, CP; Li, YY; Xiong, Z; Yang, HP | 1 |
| Feng, Q; Huang, W; Shi, X; Wang, X; Yang, M; Zhou, DH | 1 |
| Chen, YC; Gao, Y; Jia, L; Li, B; Li, W; Tu, Y | 1 |
| de Bari, L; Manente, GA; Moro, L; Mutti, L; Rossi, L; Vacca, RA; Valenti, D | 1 |
| Feng, X; Feng, Y; Li, X; Liu, J; Tang, X; Zhou, K | 1 |
| Fukusato, T; Kubota, S; Muraguchi, T; Sakamoto, Y; Terashita, N | 1 |
| Hayakawa, Y; Kaneto, N; Kato, S; Kin, R; Li, F; Saiki, I; Sakurai, H; Tanaka, K; Yokoyama, S | 1 |
| Forester, SC; Lambert, JD | 1 |
| Ahn, J; Kim, BM; Lee, JS; Yang, KM; Yoon, JW | 1 |
| Gao, F; Jiang, ZB; Jin, LY; Li, C; Liu, JX; Ma, YC; Xu, Y | 1 |
| Feng, L; Jia, XB; Jin, P; Jin, X; Liu, WB; Tan, XB; Zhu, FX | 1 |
| Li, H; Sun, X; Xie, P; Xing, L; Yu, J; Zhang, X; Zhao, H; Zhu, W | 1 |
| Levine, A; Sun, Y; Yi, L | 1 |
| Chen, JX; Jin, H; Li, G; Lin, Y; Liu, A; Lu, G; Tu, S; Wang, H; Yang, CS | 1 |
| Chen, JX; Deng, Y; Wang, H; Yang, CS; Yang, MQ; Zhou, H | 1 |
| Khan, N; Mukhtar, H | 1 |
| Chen, X; Li, X; Sun, X; Xie, P; Xing, L; Yu, J; Zhao, H; Zhu, W | 1 |
| Cromie, MM; Gao, W | 1 |
| Feng, Q; Jiang, P; Li, A; Li, Y; Shen, X; Wang, P; Wang, X; Zhou, J | 1 |
| Arechaga-Ocampo, E; Astudillo-de la Vega, H; Carlos-Reyes, Á; Chávez, JD; Flores-Pérez, A; González-Pérez, A; López-Camarillo, C; Marchat, LA; Ramírez-Torres, N; Romero-Zamora, D; Ruiz-García, E; Sánchez, LL | 1 |
| An, J; Cao, LM; Gu, QH; Hu, CP; Li, JJ; Li, M; Yang, HP | 1 |
| Chen, PN; Chu, SC; Horng, CT; Hsieh, YH; Hsieh, YS; Huang, SF | 1 |
| Gagat, M; Grzanka, A; Hałas, M; Izdebska, M; Klimaszewska-Wiśniewska, A | 1 |
| Feng, Q; Huang, W; Jiang, P; Wang, X; Wu, X | 1 |
| Lioutikova, E; Manthey, J; Wang, H; Yang, MQ; Yang, W; Yoshigoe, K; Zhou, H | 1 |
| Chen, X; Huang, Z; Lei, Z; Luo, Z; Peng, C; Su, J; Zeng, W; Zhang, J; Zhang, X; Zhou, Y | 1 |
| Chen, Y; Geng, S; Huang, C; Jiang, Y; Li, X; Li, Y; Ma, X; Meng, Y; Wang, S; Wang, X; Wu, J; Wu, R; Xie, C; Yang, X; Zhong, C; Zhu, J; Zhu, M | 1 |
| Das, S; Manna, S; Mukherjee, S; Panda, CK; Roy, A | 1 |
| Jin, H; Lin, Y; Lu, G; Snagaski, B; Xiao, H; Yang, CS; You, H | 1 |
| An, Y; Li, Z; Wang, S; Wang, Z | 1 |
| Chung, IM; Kim, MY; Lee, SJ; Moon, HI; Park, KD; Park, WH; Park, WW | 1 |
| Sasaki, K; Yamauchi, R; Yoshida, K | 1 |
| Chen, DR; Chen, R; Fu, H; Hara, Y; He, J; Lubet, RA; Mei, F; Ryota, S; You, M; Zhang, Q | 1 |
| Bode, AM; Dong, Z | 1 |
| Gao, Z; Gong, M; Hung, MS; Jablon, DM; Lin, YC; Wang, T; Xu, Z; You, L; Zhi, X | 1 |
| Bigelow, RL; Burke, P; Cardelli, JA; Carroll, JL; Coleman, DT; Milligan, SA; Steffan, JJ; Williams, BJ | 1 |
| Asai, T; Hakamata, W; Kinouchi Shimizu, N; Oku, N; Shimizu, K; Unno, K | 1 |
| Fu, H; Hara, Y; He, J; Lubet, RA; Pan, J; Ryota, S; Wang, Y; You, M; Zhang, Q | 1 |
| Chen, YK; Guan, F; Hou, Z; Jin, H; Lee, MJ; Li, GX; Liu, B; Lu, G; Xiao, H; Yang, CS; Yang, Z; Yu, A | 1 |
| Bellistri, JP; Borgovan, T; Desai, M; Joe, AK; Kopelovich, L; Slack, KN | 1 |
| Bode, AM; Chae, JI; Dong, Z; Kim, DJ; Ma, WY; Shim, JH; Su, ZY; Yang, CS; Zhu, F | 1 |
| Han, W; Shi, M; Spivack, SD; Tan, XL; Tang, H | 1 |
| Echigo, N; Fujiki, H; Kuzuhara, T; Saha, A; Suganuma, M | 1 |
| Go, VL; Jin, YS; Lu, QY; Mao, JT; Nie, WX; Rao, JY; Serio, KJ; Tsu, IH; Zhang, ZF | 1 |
| Bian, S; Wang, H; Yang, CS | 1 |
| Deng, YT; Lin, JK | 1 |
| Chie, EK; Kim, HJ; Kim, IA; Kim, IH; Kim, JH; Young, PD | 1 |
| Blancafort, A; Cufí, S; Haro, D; Marrero, PF; Oliveras, G; Puig, T; Relat, J | 1 |
| Hsu, SR; Kao, JY; Liu, LC; Tsai, TC; Tsao, TC; Wang, HC; Way, TD | 1 |
| He, L; Le, AD; Li, X; Shi, J; Tang, X; Zhang, E; Zhang, Q; Zhou, K | 1 |
| Furukawa, F; Hirose, M; Imazawa, T; Natsume, M; Nishikawa, A; Okazaki, K; Osakabe, N; Yamagishi, M | 1 |
| Chung, FL; Herzog, CR; Schwartz, J; Yang, YM | 1 |
| Hitsuda, Y; Igishi, T; Kodani, M; Matsumoto, S; Nakanishi, H; Shigeoka, Y; Shimizu, E; Yasuda, K | 1 |
| Anderson, MW; Lam, S; LeRiche, JC; Tichelaar, JW; Zhang, Y | 1 |
| Liu, J; Wei, D; Yang, J | 1 |
| Banerjee, S; Das, S; Manna, S; Panda, CK; Saha, P | 1 |
| Banerjee, S; Das, S; Ganguly, C; Manna, S; Panda, CK; Saha, P | 1 |
| Clark, J; You, M | 1 |
| Fujiki, H; Kurusu, M; Suganuma, M; Suzuki, K; Tasaki, E | 1 |
| Hara, Y; Lubet, RA; Tan, Q; Wang, Y; Yan, Y; You, M; Yun, TK | 1 |
| Banerjee, S; Das, S; Manna, S; Panda, CK; Roy, A; Saha, P | 1 |
| Adhami, VM; Kweon, MH; Lee, JS; Mukhtar, H | 1 |
| Hao, X; Liao, J; Lu, G; Reuhl, KR; Yang, CS; Yang, G | 1 |
| Fujiki, H; Kuzuhara, T; Sei, Y; Suganuma, M; Tanabe, A; Yamaguchi, K | 1 |
| Cook, J; Hitzman, CJ; McQuillan, J; Wang, Y; Wiedmann, TS; Yan, Y; You, M; Zhang, G | 1 |
| Li, YQ; Yang, XY; Yuan, JH | 1 |
| Baek, SJ; Kim, HJ; Lee, BD; Lee, JG; Moon, UY; Park, SH; Park, SY; Yoon, JH; Yoon, SH | 1 |
| Lambert, JD; Sang, S; Yang, CS | 1 |
| Isemura, M; Mukae, N; Narumi, K; Nukiwa, T; Ogata, K; Satoh, K; Suzuki, Y | 1 |
| Kuttan, G; Kuttan, R; Menon, LG | 2 |
| Chen, WF; Ho, CT; Hong, JY; Shi, ST; Smith, TJ; Wang, ZY; Yang, CS | 1 |
| Isemura, M; Motomiya, M; Narumi, K; Satoh, K; Suzuki, Y | 1 |
| Abe, S; Fujiki, H; Hara, K; Kim, SJ; Komori, A; Okabe, S; Suganuma, M; Yatsunami, J | 1 |
| Akagi, K; Hara, Y; Hirose, M; Hoshiya, T; Ito, N; Takahashi, S | 1 |
| Chung, FL; Eklind, KI; Morse, MA; Xu, Y | 1 |
| Isemura, M; Murakami, S; Nukiwa, T; Satoh, K; Sazuka, M | 1 |
| Fujiki, H; Hayashi, M; Komori, A; Okabe, S; Sueoka, E; Suganuma, M | 1 |
| Hara, Y; Imazawa, H; Isemura, M; Mita, T; Sazuka, M; Shoji, Y | 1 |
| Bondoc, F; Ding, W; Kim, S; Liao, J; Liu, Z; Seril, DN; Yang, CS; Yang, GY | 1 |
| Kim, K; Liao, J; Yang, CS; Yang, GY; Yurkow, EJ | 1 |
| Isemura, M; Isemura, S; Sazuka, M | 1 |
| Chang, CS; Chiang, TA; Ko, YC; Wang, LF; Wu, PF | 1 |
| Fujiki, H; Kai, Y; Okabe, S; Sueoka, E; Sueoka, N; Suganuma, M | 1 |
| Harada, M; Kataoka, M; Kiura, K; Matsuo, K; Mimoto, J; Takata, I; Ueoka, H; Yoshino, T | 1 |
| Aiello, FB; Brunetti, M; Caltagirone, S; Natali, PG; Piantelli, M; Poggi, A; Ranelletti, FO; Rossi, C | 1 |
| Arts, IC; Bueno De Mesquita, HB; Feskens, EJ; Hollman, PC; Kromhout, D | 1 |
| Akagi, K; Hirose, M; Hoshiya, T; Mizoguchi, Y; Nakamura, A; Shirai, T | 1 |
| Fujiki, H; Fujimoto, N; Goto, Y; Imai, K; Matsuyama, S; Nakachi, K; Okabe, S; Sueoka, E; Sueoka, N; Suganuma, M | 1 |
| Fujiki, H; Fujimoto, N; Okabe, S; Sueoka, N; Suganuma, M | 1 |
| Chen, SH; Liang, YC; Lin, CL; Liu, JD; Tsai, SH | 1 |
| Fujiki, H; Fujimoto, N; Harada, M; Okabe, S; Sueoka, E; Sueoka, N; Suganuma, M | 1 |
| Fujiki, H; Go, H; Kobayashi, H; Miyado, K; Sadano, H; Shimokawa, R; Taniguchi, S | 1 |
| Amin, SG; Chung, FL; Han, C; Ho, CT; Xu, Y | 1 |
7 review(s) available for catechin and Lung Neoplasms
| Article | Year |
|---|---|
Role of EGCG in Containing the Progression of Lung Tumorigenesis - A Multistage Targeting Approach.
Topics: Animals; Anticarcinogenic Agents; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Antioxidants; Camellia sinensis; Catechin; Cell Line, Tumor; Humans; Intercellular Signaling Peptides and Proteins; Lung Neoplasms; Molecular Structure; Signal Transduction | 2018 |
Dietary agents for prevention and treatment of lung cancer.
Topics: Adenocarcinoma; Administration, Oral; Animals; Anticarcinogenic Agents; Antineoplastic Agents, Phytogenic; Catechin; Curcumin; Flavonoids; Flavonols; Humans; Indoles; Isothiocyanates; Lung Neoplasms; Plant Extracts; Polyphenols | 2015 |
Epigallocatechin 3-gallate and green tea catechins: United they work, divided they fail.
Topics: Adenoma; Aerosols; Animals; Anticarcinogenic Agents; Antioxidants; Benzo(a)pyrene; Biological Availability; Catechin; Cell Line, Tumor; Drug Screening Assays, Antitumor; Drug Synergism; Flavonoids; Humans; Lung Neoplasms; Mice; Mice, Inbred A; Models, Biological; Neoplasms; Phenols; Phytotherapy; Polyphenols; Protein Binding; Tea | 2009 |
Tea and cancer prevention: studies in animals and humans.
Topics: Animals; Apoptosis; Caffeine; Catechin; Clinical Trials as Topic; Flavonoids; Humans; Lung Neoplasms; Mice; Mouth Neoplasms; Neoplasms; Phenols; Polyphenols; Rats; Smoking; Tea | 2003 |
Chemoprevention of lung cancer by tea.
Topics: Animals; Antioxidants; Apoptosis; Catechin; Cell Division; Chemoprevention; Disease Models, Animal; Female; Flavonoids; Humans; Lung Neoplasms; Male; Phenols; Polyphenols; Tea; Tumor Necrosis Factor-alpha | 2006 |
Inhibition of tobacco-specific nitrosamine-induced lung tumorigenesis by compounds derived from cruciferous vegetables and green tea.
Topics: Adenoma; Animals; Anticarcinogenic Agents; Antioxidants; Carcinogens; Catechin; DNA; DNA Damage; Indoles; Isothiocyanates; Lung Neoplasms; Mice; Mice, Inbred A; Nitrosamines; Rats; Rats, Inbred F344; Tea; Thiocyanates; Vegetables | 1993 |
Cancer prevention with green tea and monitoring by a new biomarker, hnRNP B1.
Topics: Animals; Anticarcinogenic Agents; Biomarkers, Tumor; Carcinoma, Squamous Cell; Catechin; Chemoprevention; Cohort Studies; Drug Synergism; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Heterogeneous-Nuclear Ribonucleoprotein Group A-B; Heterogeneous-Nuclear Ribonucleoproteins; Humans; Intestinal Neoplasms; Japan; Lung Neoplasms; Male; Mice; Mice, Mutant Strains; Okadaic Acid; Oligonucleotide Array Sequence Analysis; Prospective Studies; Ribonucleoproteins; Sulindac; Tea; Tumor Cells, Cultured | 2001 |
4 trial(s) available for catechin and Lung Neoplasms
| Article | Year |
|---|---|
A prospective, three-arm, randomized trial of EGCG for preventing radiation-induced esophagitis in lung cancer patients receiving radiotherapy.
Topics: Acute Disease; Aged; Carcinoma, Non-Small-Cell Lung; Catechin; Chemoradiotherapy; Esophagitis; Female; Humans; Lung Neoplasms; Male; Middle Aged; Neoplasm Staging; Prospective Studies; Radiation Injuries; Radiation-Protective Agents; Radiotherapy Dosage | 2019 |
A Pilot Study of a Grape Seed Procyanidin Extract for Lung Cancer Chemoprevention.
Topics: Administration, Oral; Aged; Antineoplastic Agents, Phytogenic; Apoptosis; Biflavonoids; Biopsy; Bronchi; Bronchoscopy; Catechin; Cell Proliferation; Down-Regulation; Female; Gene Expression Regulation, Neoplastic; Grape Seed Extract; Humans; Ki-67 Antigen; Lung Neoplasms; Male; MicroRNAs; Middle Aged; Proanthocyanidins; Smoking; Treatment Outcome | 2019 |
A phase I study of concurrent chemotherapy and thoracic radiotherapy with oral epigallocatechin-3-gallate protection in patients with locally advanced stage III non-small-cell lung cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Catechin; Chemoradiotherapy; Cisplatin; Esophagitis; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Neoplasm Staging; Radiotherapy Dosage | 2014 |
A prospective phase II trial of EGCG in treatment of acute radiation-induced esophagitis for stage III lung cancer.
Topics: Adult; Aged; Catechin; Esophagitis; Female; Humans; Lung Neoplasms; Male; Middle Aged; Neoplasm Staging; Prospective Studies; Quality of Life; Radiation Injuries | 2015 |
118 other study(ies) available for catechin and Lung Neoplasms
| Article | Year |
|---|---|
Effect of EGCG on bronchial epithelial cell premalignant lesions induced by cigarette smoke and on its CYP1A1 expression.
Topics: Animals; Bronchi; Catechin; Cell Line; Cell Transformation, Neoplastic; Cytochrome P-450 CYP1A1; Epithelial Cells; Female; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; MicroRNAs; Rats; Rats, Sprague-Dawley; Signal Transduction; Smoke; Smoking | 2021 |
Effect of Epigallocatechin-3-Gallate on EGFR Signaling and Migration in Non-Small Cell Lung Cancer.
Topics: A549 Cells; Carcinoma, Non-Small-Cell Lung; Catechin; ErbB Receptors; Humans; Lung Neoplasms; Neoplasm Proteins; Signal Transduction | 2021 |
Low dose epigallocatechin-3-gallate revives doxorubicin responsiveness by a redox-sensitive pathway in A549 lung adenocarcinoma cells.
Topics: A549 Cells; Adenocarcinoma of Lung; Catechin; Doxorubicin; Humans; Lung Neoplasms; Oxidation-Reduction | 2022 |
Green tea-derived theabrownin suppresses human non-small cell lung carcinoma in xenograft model through activation of not only p53 signaling but also MAPK/JNK signaling pathway.
Topics: Animals; Apoptosis; Carcinoma, Non-Small-Cell Lung; Catechin; Cell Line, Tumor; Cell Movement; Cell Proliferation; Heterografts; Humans; Lung Neoplasms; MAP Kinase Signaling System; Tea; Tumor Suppressor Protein p53; Zebrafish | 2022 |
Dimeric-(-)-epigallocatechin-3-gallate inhibits the proliferation of lung cancer cells by inhibiting the EGFR signaling pathway.
Topics: Animals; Apoptosis; Carcinoma, Non-Small-Cell Lung; Catechin; Cell Line, Tumor; Cell Proliferation; ErbB Receptors; Lung Neoplasms; Signal Transduction | 2022 |
(-)-Epigallocatechin gallate inhibits stemness and tumourigenicity stimulated by AXL receptor tyrosine kinase in human lung cancer cells.
Topics: Animals; Anticarcinogenic Agents; Axl Receptor Tyrosine Kinase; Carcinogenesis; Catechin; Cell Line, Tumor; Female; Humans; Lung Neoplasms; Mice, SCID; Neoplastic Stem Cells; Proto-Oncogene Proteins; Receptor Protein-Tyrosine Kinases | 2020 |
Anticancer effects of epigallocatechin-3-gallate nanoemulsion on lung cancer cells through the activation of AMP-activated protein kinase signaling pathway.
Topics: AMP-Activated Protein Kinases; Catechin; Cell Line, Tumor; Cell Movement; Cell Proliferation; Drug Delivery Systems; Humans; Lung Neoplasms; MAP Kinase Signaling System; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Signal Transduction | 2020 |
Identification of luteolin -7-glucoside and epicatechin gallate from
Topics: Carcinoma, Non-Small-Cell Lung; Catechin; ErbB Receptors; Glucosides; Humans; Lung Neoplasms; Luteolin; Molecular Docking Simulation; Molecular Dynamics Simulation; Mutation; Protein Binding; Protein Kinase Inhibitors; Vernonia | 2021 |
Enhanced Chemotherapeutic Efficacy of PLGA-Encapsulated Epigallocatechin Gallate (EGCG) Against Human Lung Cancer.
Topics: Antineoplastic Agents; Apoptosis; Catechin; Cell Line, Tumor; Cell Survival; Drug Liberation; Endocytosis; Humans; Lung Neoplasms; Nanoparticles; NF-kappa B; Polylactic Acid-Polyglycolic Acid Copolymer | 2020 |
Enhancement of Phthalocyanine Mediated Photodynamic Therapy by Catechin on Lung Cancer Cells.
Topics: A549 Cells; Antineoplastic Agents; Apoptosis; Catechin; Cell Proliferation; DNA Damage; Dose-Response Relationship, Drug; Drug Synergism; Humans; Indoles; Isoindoles; Lung Neoplasms; Organometallic Compounds; Photochemotherapy; Photosensitizing Agents; Reactive Oxygen Species; Zinc Compounds | 2020 |
Epigallocatechin‑3‑gallate inhibits self‑renewal ability of lung cancer stem‑like cells through inhibition of CLOCK.
Topics: Animals; Catechin; Cell Line, Tumor; Cell Self Renewal; Circadian Rhythm; CLOCK Proteins; Female; Humans; Lung Neoplasms; Mice, Inbred BALB C; Mice, Nude; Neoplastic Stem Cells; Up-Regulation; Wnt Signaling Pathway | 2020 |
Theaflavin binds to a druggable pocket of TMEM16A channel and inhibits lung adenocarcinoma cell viability.
Topics: Adenocarcinoma of Lung; Anoctamin-1; Antineoplastic Agents; Biflavonoids; Binding Sites; Catechin; Cell Line, Tumor; Cell Movement; Cell Proliferation; Humans; Lung Neoplasms; Molecular Dynamics Simulation; Neoplasm Proteins | 2021 |
NEAT1 acts as an inducer of cancer stem cell-like phenotypes in NSCLC by inhibiting EGCG-upregulated CTR1.
Topics: A549 Cells; Antineoplastic Agents, Phytogenic; Carcinoma, Non-Small-Cell Lung; Catechin; Cation Transport Proteins; Copper Transporter 1; Epithelial-Mesenchymal Transition; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; Neoplastic Stem Cells; Phenotype; RNA, Long Noncoding; Wnt Signaling Pathway | 2018 |
Metformin Sensitizes Non-small Cell Lung Cancer Cells to an Epigallocatechin-3-Gallate (EGCG) Treatment by Suppressing the Nrf2/HO-1 Signaling Pathway.
Topics: Animals; Apoptosis; Carcinoma, Non-Small-Cell Lung; Catechin; Cell Line; Cell Line, Tumor; Female; Heme Oxygenase-1; Humans; Lung Neoplasms; Metformin; Mice; Mice, Inbred BALB C; Mice, Nude; NF-E2-Related Factor 2; Promoter Regions, Genetic; Reactive Oxygen Species; Signal Transduction | 2017 |
Effects of (-)-epigallocatechin-3-gallate on EGFR- or Fusion Gene-driven Lung Cancer Cells.
Topics: Anaplastic Lymphoma Kinase; Animals; Blood Proteins; Blotting, Western; Carcinoma, Non-Small-Cell Lung; Catechin; Cell Line, Tumor; Crizotinib; Disease Models, Animal; ErbB Receptors; Female; Gene Rearrangement; Heterografts; Humans; Lung Neoplasms; Mice; Mice, Inbred BALB C; Mice, Nude; Mutation; Oncogene Proteins, Fusion; Polyphenols; Protein S; Protein-Tyrosine Kinases; Pyrazoles; Pyridines; Receptor Protein-Tyrosine Kinases; Tea | 2017 |
TriCurin, a synergistic formulation of curcumin, resveratrol, and epicatechin gallate, repolarizes tumor-associated macrophages and triggers an immune response to cause suppression of HPV+ tumors.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Catechin; Curcumin; Female; Head and Neck Neoplasms; Humans; Killer Cells, Natural; Lung Neoplasms; Macrophages; Mice; Mice, Inbred C57BL; Mice, Nude; Papillomaviridae; Papillomavirus Infections; Resveratrol; T-Lymphocytes, Cytotoxic; Tumor Cells, Cultured; Xenograft Model Antitumor Assays | 2018 |
Immuno-modulators enhance antigen-specific immunity and anti-tumor effects of mesothelin-specific chimeric DNA vaccine through promoting DC maturation.
Topics: Animals; Antibodies, Monoclonal; Antineoplastic Combined Chemotherapy Protocols; Cancer Vaccines; Catechin; Cell Line, Tumor; Connective Tissue Growth Factor; Dendritic Cells; Drug Synergism; Female; GPI-Linked Proteins; Lung Neoplasms; Mesothelin; Mesothelioma; Mesothelioma, Malignant; Mice; Poly I-C; Treatment Outcome; Vaccines, DNA; Xenograft Model Antitumor Assays | 2018 |
Characterization of the cytotoxic effects of the combination of cisplatin and flavanol (-)-epicatechin on human lung cancer cell line A549. An isobolographic approach.
Topics: A549 Cells; Adenocarcinoma; Adenocarcinoma of Lung; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Catechin; Cell Proliferation; Cell Survival; Cisplatin; Drug Synergism; Humans; Lung Neoplasms | 2018 |
(-)- Epigallocatechin-3-gallate induces GRP78 accumulation in the ER and shifts mesothelioma constitutive UPR into proapoptotic ER stress.
Topics: Apoptosis; Catechin; Cell Survival; Endoplasmic Reticulum; Endoplasmic Reticulum Chaperone BiP; Endoplasmic Reticulum Stress; Heat-Shock Proteins; Homeostasis; Humans; Lung Neoplasms; Mesothelioma; Mesothelioma, Malignant; Molecular Chaperones | 2018 |
Study of EGCG induced apoptosis in lung cancer cells by inhibiting PI3K/Akt signaling pathway.
Topics: A549 Cells; Apoptosis; Carcinoma, Non-Small-Cell Lung; Catechin; Cell Proliferation; Cell Survival; Drug Screening Assays, Antitumor; Humans; Lung Neoplasms; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Signal Transduction | 2018 |
Epigallocatechin-3-gallate inhibited cancer stem cell-like properties by targeting hsa-mir-485-5p/RXRα in lung cancer.
Topics: A549 Cells; Analysis of Variance; Animals; Anticarcinogenic Agents; Carcinoma, Non-Small-Cell Lung; Catechin; Down-Regulation; Gene Knockdown Techniques; Gene Silencing; HEK293 Cells; Humans; Lung Neoplasms; Mice; Mice, Nude; MicroRNAs; Molecular Mimicry; Neoplastic Stem Cells; Retinoid X Receptor alpha; Signal Transduction; Transfection; Up-Regulation; Xenograft Model Antitumor Assays | 2018 |
Green Tea Catechin Is an Alternative Immune Checkpoint Inhibitor that Inhibits PD-L1 Expression and Lung Tumor Growth.
Topics: Animals; Antineoplastic Agents, Phytogenic; B7-H1 Antigen; Catechin; Cell Line, Tumor; Disease Models, Animal; Gene Expression; Humans; Immunomodulation; Lung Neoplasms; Mice; Phosphorylation; Proto-Oncogene Proteins c-akt; Signal Transduction; STAT1 Transcription Factor; T-Lymphocyte Subsets; Tea; Xenograft Model Antitumor Assays | 2018 |
EGCG inhibits CSC-like properties through targeting miR-485/CD44 axis in A549-cisplatin resistant cells.
Topics: A549 Cells; Animals; Carcinoma, Non-Small-Cell Lung; Catechin; Cell Proliferation; Cell Survival; Cisplatin; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Gene Expression Regulation, Neoplastic; Humans; Hyaluronan Receptors; Lung Neoplasms; Mice; Mice, Nude; MicroRNAs; Neoplastic Stem Cells; Xenograft Model Antitumor Assays | 2018 |
Epigallocatechin‑3‑gallate modulates long non‑coding RNA and mRNA expression profiles in lung cancer cells.
Topics: Catechin; Cell Line, Tumor; Computational Biology; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; Oligonucleotide Array Sequence Analysis; RNA, Long Noncoding; RNA, Messenger; Signal Transduction | 2019 |
Next-Generation Sequencing Reveals the Role of Epigallocatechin-3-Gallate in Regulating Putative Novel and Known microRNAs Which Target the MAPK Pathway in Non-Small-Cell Lung Cancer A549 Cells.
Topics: Carcinoma, Non-Small-Cell Lung; Catechin; Cell Cycle Checkpoints; Cell Line, Tumor; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; High-Throughput Nucleotide Sequencing; Humans; Lung Neoplasms; MAP Kinase Signaling System; MicroRNAs; Nucleic Acid Conformation; Reproducibility of Results; Transcriptome | 2019 |
EGCG, a green tea polyphenol, as one more weapon in the arsenal to fight radiation esophagitis?
Topics: Catechin; Esophagitis; Humans; Lung Neoplasms; Prospective Studies; Tea; Weapons | 2019 |
A Generic Coordination Assembly-Enabled Nanocoating of Individual Tumor Cells for Personalized Immunotherapy.
Topics: Animals; Antigens; Body Weight; Bone Marrow Cells; Catechin; Cell Line, Tumor; Cell Survival; Dendritic Cells; Female; Humans; Immunotherapy; Lung Neoplasms; Mice, Inbred C57BL; Nanoparticles; Neoplasms; Photoelectron Spectroscopy; Precision Medicine | 2019 |
Inhibitory effect of black tea (Camellia sinensis) theaflavins and thearubigins against HCT 116 colon cancer cells and HT 460 lung cancer cells.
Topics: Antineoplastic Agents, Phytogenic; Antioxidants; Apoptosis; Biflavonoids; Camellia sinensis; Catechin; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Survival; Colonic Neoplasms; Drug Synergism; HCT116 Cells; Humans; Lung Neoplasms; Polyphenols; Tea | 2019 |
TGF-β1-induced epithelial-mesenchymal transition and acetylation of Smad2 and Smad3 are negatively regulated by EGCG in human A549 lung cancer cells.
Topics: Acetylation; Anticarcinogenic Agents; Antigens, CD; Cadherins; Catechin; Cell Line, Tumor; Cell Movement; Cell Survival; Epithelial-Mesenchymal Transition; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; p300-CBP Transcription Factors; Protein Binding; Protein Processing, Post-Translational; Signal Transduction; Smad2 Protein; Smad3 Protein; Transforming Growth Factor beta1; Vimentin | 2013 |
Epigallocatechin gallate promotes p53 accumulation and activity via the inhibition of MDM2-mediated p53 ubiquitination in human lung cancer cells.
Topics: Catechin; Cell Line; Cell Line, Tumor; Cell Nucleus; HEK293 Cells; Humans; Lung Neoplasms; Phosphorylation; Proteasome Endopeptidase Complex; Proto-Oncogene Proteins c-mdm2; Tea; Transcription, Genetic; Tumor Suppressor Protein p53; Ubiquitination; Up-Regulation | 2013 |
Preclinical demonstration of synergistic Active Nutrients/Drug (AND) combination as a potential treatment for malignant pleural mesothelioma.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Ascorbic Acid; Catechin; Cell Line, Tumor; Cell Proliferation; Deoxycytidine; Drug Synergism; Gemcitabine; Humans; Lung Neoplasms; Male; Mesothelioma; Mesothelioma, Malignant; Mice; Mice, Inbred NOD; Mice, SCID; Pleural Neoplasms; Signal Transduction; Xenograft Model Antitumor Assays | 2013 |
Treatment with EGCG in NSCLC leads to decreasing interstitial fluid pressure and hypoxia to improve chemotherapy efficacy through rebalance of Ang-1 and Ang-2.
Topics: Angiogenesis Inhibitors; Angiopoietin-1; Angiopoietin-2; Animals; Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Catechin; Chemotherapy, Adjuvant; Cisplatin; Drug Therapy, Combination; Extracellular Fluid; Female; Humans; Lung Neoplasms; Mice; Mice, Inbred BALB C; Mice, Nude; Oxygen | 2013 |
Combination of low concentration of (-)-epigallocatechin gallate (EGCG) and curcumin strongly suppresses the growth of non-small cell lung cancer in vitro and in vivo through causing cell cycle arrest.
Topics: Animals; Anticarcinogenic Agents; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Catechin; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Clone Cells; Curcumin; Cyclin B1; Cyclin D1; DNA Replication; Female; Lung Neoplasms; Mice, Inbred BALB C; Mice, Nude | 2013 |
Enhancement of (-)-epigallocatechin-3-gallate and theaflavin-3-3'-digallate induced apoptosis by ascorbic acid in human lung adenocarcinoma SPC-A-1 cells and esophageal carcinoma Eca-109 cells via MAPK pathways.
Topics: Adenocarcinoma; Anticarcinogenic Agents; Antineoplastic Agents; Apoptosis; Ascorbic Acid; Biflavonoids; Caspase 3; Caspase 9; Catechin; Cell Line, Tumor; Enzyme Inhibitors; Esophageal Neoplasms; Gallic Acid; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; MAP Kinase Signaling System | 2013 |
Negative modulation of mitochondrial oxidative phosphorylation by epigallocatechin-3 gallate leads to growth arrest and apoptosis in human malignant pleural mesothelioma cells.
Topics: Adenosine Triphosphate; Apoptosis; Catalase; Catechin; Cell Cycle; Cell Proliferation; Cells, Cultured; Cytochromes c; Electron Transport Complex I; Electron Transport Complex II; Epithelial Cells; Humans; Immunoblotting; Lung Neoplasms; Mesothelioma; Mesothelioma, Malignant; Mitochondria; Mitochondrial Proton-Translocating ATPases; Oxidative Phosphorylation; Pleural Neoplasms; Reactive Oxygen Species; Superoxide Dismutase | 2013 |
Epigallocatechin-3-gallate inhibits IGF-I-stimulated lung cancer angiogenesis through downregulation of HIF-1α and VEGF expression.
Topics: Base Sequence; Catechin; Cell Line, Tumor; DNA Primers; Down-Regulation; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Insulin-Like Growth Factor I; Lung Neoplasms; Neovascularization, Pathologic; Real-Time Polymerase Chain Reaction; Vascular Endothelial Growth Factor A | 2013 |
Effects of epigallocatechin-3-gallate (EGCG) on A549 lung cancer tumor growth and angiogenesis.
Topics: Animals; Antineoplastic Agents; Catechin; Cell Line, Tumor; Cell Proliferation; Cell Survival; Endostatins; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; Male; Mice; Mice, Inbred BALB C; Neovascularization, Pathologic; RNA, Messenger; Vascular Endothelial Growth Factor A; Xenograft Model Antitumor Assays | 2013 |
Procyanidin C1 from Cinnamomi Cortex inhibits TGF-β-induced epithelial-to-mesenchymal transition in the A549 lung cancer cell line.
Topics: Biflavonoids; Cadherins; Catechin; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cinnamomum zeylanicum; Drugs, Chinese Herbal; Epithelial-Mesenchymal Transition; Humans; Lung Neoplasms; Neoplasm Metastasis; Plant Extracts; Proanthocyanidins; Smad2 Protein; Transforming Growth Factor beta | 2013 |
Synergistic inhibition of lung cancer cell lines by (-)-epigallocatechin-3-gallate in combination with clinically used nitrocatechol inhibitors of catechol-O-methyltransferase.
Topics: Animals; Anticarcinogenic Agents; Apoptosis; Benzophenones; Blotting, Western; Catechin; Catechol O-Methyltransferase Inhibitors; Catechols; Cell Cycle; Cell Proliferation; Cell-Free System; DNA Methylation; Drug Synergism; Enzyme Inhibitors; Humans; Lung Neoplasms; Male; Mice; Nitriles; Nitro Compounds; Nitrophenols; Oxidative Stress; Reactive Oxygen Species; Tolcapone; Tumor Cells, Cultured | 2014 |
Catechin-7-O-xyloside induces apoptosis via endoplasmic reticulum stress and mitochondrial dysfunction in human non-small cell lung carcinoma H1299 cells.
Topics: Animals; Apoptosis; Carcinoma, Non-Small-Cell Lung; Caspase 6; Catechin; Cell Line, Tumor; Endoplasmic Reticulum Stress; Humans; L-Lactate Dehydrogenase; Lung Neoplasms; Membrane Potential, Mitochondrial; Mice; Mice, Inbred BALB C; Mice, Nude; Mitochondria; Neoplasm Transplantation; Poly(ADP-ribose) Polymerases; RNA Interference; RNA, Messenger; RNA, Small Interfering; Transcription Factor CHOP; Xylose | 2014 |
Epigallocatechin gallate inhibits the growth of human lung cancer by directly targeting the EGFR signaling pathway.
Topics: Antineoplastic Agents; Catechin; Cell Adhesion; Cell Line, Tumor; Cell Proliferation; Cyclin D1; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; ErbB Receptors; G1 Phase Cell Cycle Checkpoints; Gene Expression; Gene Knockdown Techniques; Humans; Lung Neoplasms; Signal Transduction | 2014 |
[Study on effective substances of tea for chemoprevention of lung cancer based on principal component analysis].
Topics: Anticarcinogenic Agents; Antineoplastic Agents, Phytogenic; Bronchi; Catechin; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Gallic Acid; Humans; Lung Neoplasms; Plant Extracts; Principal Component Analysis; Smoke; Smoking; Tea | 2013 |
Selected drugs that inhibit DNA methylation can preferentially kill p53 deficient cells.
Topics: Animals; Anticarcinogenic Agents; Azacitidine; Catechin; Cell Line, Tumor; Cell Proliferation; Cytidine; Decitabine; DNA Methylation; Humans; Lung Neoplasms; Mice; Mice, Inbred C57BL; Mice, Knockout; Mutation; Neoplasm Transplantation; Phthalimides; Tryptophan; Tumor Suppressor Protein p53; Xenograft Model Antitumor Assays | 2014 |
NNK-induced DNA methyltransferase 1 in lung tumorigenesis in A/J mice and inhibitory effects of (-)-epigallocatechin-3-gallate.
Topics: Animals; Anticarcinogenic Agents; Antineoplastic Agents, Phytogenic; Bronchi; Carcinogenesis; Carcinogens; Catechin; Dietary Supplements; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Female; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Lung; Lung Neoplasms; Mice, Inbred A; Neoplasm Proteins; Nitrosamines; Promoter Regions, Genetic; Respiratory Mucosa | 2015 |
Gene regulation mediated by microRNAs in response to green tea polyphenol EGCG in mouse lung cancer.
Topics: Animals; Anticarcinogenic Agents; Camellia sinensis; Carcinogens; Catechin; Cell Cycle Proteins; Female; Gene Expression Regulation; Lung Neoplasms; Mice; MicroRNAs; Mitogen-Activated Protein Kinases; NF-kappa B; Nitrosamines; Polyphenols; Proto-Oncogene Proteins c-akt | 2014 |
Epigallocatechin-3-gallate enhances the therapeutic effects of leptomycin B on human lung cancer a549 cells.
Topics: Acetylcysteine; Antineoplastic Agents; Apoptosis; Catechin; Cell Line, Tumor; Cyclin-Dependent Kinase Inhibitor p21; Cytochrome P-450 CYP3A; Down-Regulation; Fatty Acids, Unsaturated; Glutathione Peroxidase; Glutathione Peroxidase GPX1; Humans; Inhibitor of Apoptosis Proteins; Lung Neoplasms; Reactive Oxygen Species; Superoxide Dismutase; Survivin; Up-Regulation | 2015 |
EGCG regulates the cross-talk between JWA and topoisomerase IIα in non-small-cell lung cancer (NSCLC) cells.
Topics: Animals; Antigens, Neoplasm; Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Catechin; Cell Line, Tumor; DNA Topoisomerases, Type II; DNA-Binding Proteins; Female; Heat-Shock Proteins; Humans; Intracellular Signaling Peptides and Proteins; Lung Neoplasms; Membrane Transport Proteins; Mice, Inbred BALB C; Mice, Nude; Proteolysis; Xenograft Model Antitumor Assays | 2015 |
Differential proteomic analysis reveals that EGCG inhibits HDGF and activates apoptosis to increase the sensitivity of non-small cells lung cancer to chemotherapy.
Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Carcinoma, Non-Small-Cell Lung; Catechin; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Humans; Intercellular Signaling Peptides and Proteins; Lung Neoplasms; Proteomics; Structure-Activity Relationship; Tumor Cells, Cultured | 2016 |
EGCG induces lung cancer A549 cell apoptosis by regulating Ku70 acetylation.
Topics: A549 Cells; Acetylation; Anticarcinogenic Agents; Apoptosis; bcl-2-Associated X Protein; bcl-X Protein; Caspase 3; Catechin; Cell Survival; Gene Expression Regulation, Neoplastic; Humans; Ku Autoantigen; Lung Neoplasms | 2016 |
Epicatechin-3-gallate reverses TGF-β1-induced epithelial-to-mesenchymal transition and inhibits cell invasion and protease activities in human lung cancer cells.
Topics: Animals; Catechin; Cell Line, Tumor; Epithelial-Mesenchymal Transition; Heterografts; Humans; Lung Neoplasms; Matrix Metalloproteinase 2; Mice; Neoplasm Invasiveness; Signal Transduction; Transforming Growth Factor beta1 | 2016 |
Green tea extract induces protective autophagy in A549 non-small lung cancer cell line.
Topics: Antioxidants; Autophagy; Carcinoma, Non-Small-Cell Lung; Catechin; Cell Line; Humans; Lung Neoplasms; Plant Extracts; Polyphenols; Tea | 2015 |
NEAT1 upregulates EGCG-induced CTR1 to enhance cisplatin sensitivity in lung cancer cells.
Topics: A549 Cells; Animals; Anticarcinogenic Agents; Carcinoma, Non-Small-Cell Lung; Catechin; Cation Transport Proteins; Cell Proliferation; Chemotherapy, Adjuvant; Cisplatin; Copper Transporter 1; Down-Regulation; Drug Resistance, Neoplasm; Female; Gene Expression Regulation, Neoplastic; Humans; Lung; Lung Neoplasms; Mice; Mice, Nude; MicroRNAs; Microscopy, Fluorescence; RNA Interference; RNA, Long Noncoding; RNA, Small Interfering; Up-Regulation; Xenograft Model Antitumor Assays | 2016 |
The up-regulation of Myb may help mediate EGCG inhibition effect on mouse lung adenocarcinoma.
Topics: Adenocarcinoma; Animals; Antioxidants; Catechin; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Gene Regulatory Networks; Kruppel-Like Transcription Factors; Lung; Lung Neoplasms; Mice, Inbred Strains; MicroRNAs; Proto-Oncogene Proteins c-myb; Up-Regulation | 2016 |
Epigallocatechin-3-gallate(EGCG) suppresses melanoma cell growth and metastasis by targeting TRAF6 activity.
Topics: Animals; Antineoplastic Agents, Phytogenic; Catechin; Cell Line, Tumor; Cell Movement; Cell Proliferation; Enzyme Inhibitors; Gene Expression Regulation, Neoplastic; HEK293 Cells; Humans; Intracellular Signaling Peptides and Proteins; Lung Neoplasms; MAP Kinase Kinase Kinases; Melanoma; Mice, Inbred BALB C; Molecular Docking Simulation; Neoplasm Invasiveness; NF-kappa B; NF-KappaB Inhibitor alpha; Phosphorylation; Protein Binding; Protein Conformation; Signal Transduction; Skin Neoplasms; Structure-Activity Relationship; TNF Receptor-Associated Factor 6; Transfection; Tumor Burden; Ubiquitin-Conjugating Enzymes; Ubiquitin-Protein Ligases; Ubiquitination | 2016 |
Wnt/β-catenin pathway mediates (-)-Epigallocatechin-3-gallate (EGCG) inhibition of lung cancer stem cells.
Topics: A549 Cells; Antineoplastic Agents; Apoptosis; Catechin; Cell Line, Tumor; Cell Survival; Dose-Response Relationship, Drug; Humans; Lung Neoplasms; Neoplastic Stem Cells; Wnt Signaling Pathway | 2017 |
Tea polyphenols can restrict benzo[a]pyrene-induced lung carcinogenesis by altered expression of p53-associated genes and H-ras, c-myc and cyclin D1.
Topics: Animals; Apoptosis; Benzo(a)pyrene; Biflavonoids; Catechin; Cell Proliferation; Cell Transformation, Neoplastic; Cyclin D1; Female; Flavonoids; Lung; Lung Neoplasms; Male; Mice; Phenols; Polyphenols; Proto-Oncogene Proteins c-myc; ras Proteins; Tea; Tumor Suppressor Protein p53 | 2009 |
Synergistic inhibition of lung tumorigenesis by a combination of green tea polyphenols and atorvastatin.
Topics: Animals; Apoptosis; Atorvastatin; Catechin; Cell Line, Tumor; Cell Proliferation; Drug Synergism; Female; Flavonoids; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lung Neoplasms; Mice; Phenols; Plant Extracts; Polyphenols; Pyrroles; Tea | 2008 |
[Inhibition of (-)epigallocatechin gallate on dimethylarsinic acid promoting lung tumorigenesis through the induction of oxidative stress in mice].
Topics: Animals; Antineoplastic Agents; Cacodylic Acid; Catechin; Lung Neoplasms; Male; Mice; Oxidative Stress | 2008 |
Inhibition of lung metastasis in mice by oligonol.
Topics: Animals; Antineoplastic Agents, Phytogenic; Catechin; Collagen; gamma-Glutamyltransferase; Hexosamines; Hydroxyproline; Lung; Lung Neoplasms; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Phenols; Sialic Acids; Uronic Acids | 2009 |
Identification of epigallocatechin-3-gallate in green tea polyphenols as a potent inducer of p53-dependent apoptosis in the human lung cancer cell line A549.
Topics: Apoptosis; Caspase 3; Caspase 7; Catechin; Cell Line, Tumor; Cell Survival; Flavonoids; Humans; Luciferases; Lung Neoplasms; Phenols; Polyphenols; Signal Transduction; Tea; Tumor Suppressor Protein p53 | 2009 |
Lung cancer inhibitory effect of epigallocatechin-3-gallate is dependent on its presence in a complex mixture (polyphenon E).
Topics: Adenoma; Aerosols; Animals; Anticarcinogenic Agents; Antioxidants; Benzo(a)pyrene; Biological Availability; Catechin; Drug Screening Assays, Antitumor; Drug Synergism; Female; Lung Neoplasms; Mice; Mice, Inbred A; Tea | 2009 |
Promoter demethylation of WIF-1 by epigallocatechin-3-gallate in lung cancer cells.
Topics: Adaptor Proteins, Signal Transducing; Anticarcinogenic Agents; Blotting, Western; Carcinoma, Non-Small-Cell Lung; Catechin; Cell Line, Tumor; Cell Proliferation; DNA Methylation; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Humans; Luciferases; Lung Neoplasms; Promoter Regions, Genetic; Repressor Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Urokinase-Type Plasminogen Activator | 2009 |
The green tea polyphenol EGCG potentiates the antiproliferative activity of c-Met and epidermal growth factor receptor inhibitors in non-small cell lung cancer cells.
Topics: Animals; Anticarcinogenic Agents; Carcinoma, Non-Small-Cell Lung; Catechin; Cell Line, Tumor; Cell Proliferation; ErbB Receptors; Erlotinib Hydrochloride; Humans; Indoles; Lung Neoplasms; Male; Mice; Mice, SCID; Phosphorylation; Piperazines; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-met; Quinazolines; Sulfonamides; Xenograft Model Antitumor Assays | 2009 |
Preventive effect of green tea catechins on experimental tumor metastasis in senescence-accelerated mice.
Topics: Aging; Animals; Antineoplastic Agents, Phytogenic; Camellia sinensis; Catechin; Cell Line, Tumor; Immunologic Surveillance; Killer Cells, Natural; Lung Neoplasms; Melanoma; Mice; Mice, Inbred Strains; Neoplasm Metastasis; Neoplasm Transplantation; Neoplasms, Experimental; Phytotherapy; Plant Extracts | 2010 |
Effect of dietary Polyphenon E and EGCG on lung tumorigenesis in A/J Mice.
Topics: Animals; Anticarcinogenic Agents; Catechin; Chemoprevention; Female; Lung; Lung Neoplasms; Mice | 2010 |
Pro-oxidative activities and dose-response relationship of (-)-epigallocatechin-3-gallate in the inhibition of lung cancer cell growth: a comparative study in vivo and in vitro.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Anticarcinogenic Agents; Apoptosis; Catechin; Cell Line, Tumor; Cell Proliferation; Deoxyguanosine; DNA Damage; DNA Repair; Dose-Response Relationship, Drug; Histones; Humans; Lung Neoplasms; Male; Membrane Potential, Mitochondrial; Mice; Oxidative Stress; Reactive Oxygen Species; Xenograft Model Antitumor Assays | 2010 |
Inhibition of BCL2 expression and activity increases H460 sensitivity to the growth inhibitory effects of polyphenon E.
Topics: Apoptosis; Blotting, Western; Catechin; Cell Line, Tumor; Drug Resistance, Neoplasm; Gene Expression Regulation, Neoplastic; Genes, bcl-2; Humans; Lung Neoplasms; Membrane Potentials; Mitochondrial Membranes; Poly(ADP-ribose) Polymerases; Proto-Oncogene Proteins c-bcl-2; RNA, Neoplasm; RNA, Small Interfering; Tea | 2009 |
Epigallocatechin gallate suppresses lung cancer cell growth through Ras-GTPase-activating protein SH3 domain-binding protein 1.
Topics: Anticarcinogenic Agents; Blotting, Western; Carrier Proteins; Catechin; Cell Line, Tumor; Cell Proliferation; DNA Helicases; Humans; Immunoprecipitation; Lung Neoplasms; Poly-ADP-Ribose Binding Proteins; RNA Helicases; RNA Recognition Motif Proteins; Signal Transduction; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; src Homology Domains | 2010 |
Candidate dietary phytochemicals modulate expression of phase II enzymes GSTP1 and NQO1 in human lung cells.
Topics: Anticarcinogenic Agents; Brassica; Bronchi; Camellia sinensis; Catechin; Cell Division; Cell Line; Cell Line, Tumor; Epithelial Cells; Gene Expression; Glutathione S-Transferase pi; Humans; Isothiocyanates; Lung; Lung Neoplasms; NAD(P)H Dehydrogenase (Quinone); Plant Extracts; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sulfoxides; Thiocyanates | 2010 |
New role of (-)-epicatechin in enhancing the induction of growth inhibition and apoptosis in human lung cancer cells by curcumin.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Carcinoma, Non-Small-Cell Lung; Catechin; Cell Cycle Proteins; Cell Growth Processes; Cell Line, Tumor; Curcumin; Down-Regulation; Drug Evaluation, Preclinical; Drug Synergism; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; Nuclear Proteins; Protein Kinase Inhibitors; RNA, Small Interfering; Transcription Factor CHOP | 2010 |
White tea extract induces apoptosis in non-small cell lung cancer cells: the role of peroxisome proliferator-activated receptor-{gamma} and 15-lipoxygenases.
Topics: Anilides; Apoptosis; Arachidonate 15-Lipoxygenase; Carcinoma, Non-Small-Cell Lung; Catechin; Drug Evaluation, Preclinical; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Hormone Antagonists; Humans; Hydroxyeicosatetraenoic Acids; Lung Neoplasms; Plant Extracts; PPAR gamma; Tea; Tumor Cells, Cultured | 2010 |
In vitro screening of synergistic ascorbate-drug combinations for the treatment of malignant mesothelioma.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Ascorbic Acid; Catechin; Cell Line, Tumor; Cell Proliferation; Cell Survival; Coloring Agents; Deoxycytidine; Drug Synergism; Gemcitabine; Humans; L-Lactate Dehydrogenase; Lung Neoplasms; Mesothelioma; Neutral Red | 2011 |
Green tea polyphenol EGCG suppresses lung cancer cell growth through upregulating miR-210 expression caused by stabilizing HIF-1α.
Topics: Animals; Blotting, Western; Catechin; Cell Division; Cell Line, Tumor; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Immunoprecipitation; Lung Neoplasms; Mice; MicroRNAs; Tea; Up-Regulation | 2011 |
EGCG inhibits the invasion of highly invasive CL1-5 lung cancer cells through suppressing MMP-2 expression via JNK signaling and induces G2/M arrest.
Topics: Anticarcinogenic Agents; Apoptosis; Catechin; Cell Line, Tumor; G2 Phase Cell Cycle Checkpoints; Gene Expression; Humans; Lung Neoplasms; M Phase Cell Cycle Checkpoints; MAP Kinase Signaling System; Matrix Metalloproteinase 2; Neoplasm Invasiveness; Tea | 2011 |
DNMT (DNA methyltransferase) inhibitors radiosensitize human cancer cells by suppressing DNA repair activity.
Topics: Azacitidine; Caspase 3; Catechin; Cell Line, Tumor; Cytidine; Decitabine; Disulfides; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Breaks, Double-Stranded; DNA Methyltransferase 3A; DNA Methyltransferase 3B; DNA Repair; Enzyme Induction; Gene Expression Regulation, Neoplastic; Glioblastoma; Histones; Humans; Hydralazine; Inhibitory Concentration 50; Lung Neoplasms; Neoplasm Proteins; Radiation-Sensitizing Agents; Tumor Stem Cell Assay; Tyrosine | 2012 |
Different fatty acid metabolism effects of (-)-epigallocatechin-3-gallate and C75 in adenocarcinoma lung cancer.
Topics: 4-Butyrolactone; Adenocarcinoma; Adenocarcinoma of Lung; Analysis of Variance; Animals; Apoptosis; Carnitine O-Palmitoyltransferase; Catechin; Cell Line, Tumor; Fatty Acid Synthases; Fatty Acids; Female; Humans; Lung Neoplasms; Mice; Mice, Inbred BALB C; Mice, Nude; Phosphorylation; Random Allocation; Signal Transduction; Weight Loss; Xenograft Model Antitumor Assays | 2012 |
EGCG inhibits transforming growth factor-β-mediated epithelial-to-mesenchymal transition via the inhibition of Smad2 and Erk1/2 signaling pathways in nonsmall cell lung cancer cells.
Topics: Carcinoma, Non-Small-Cell Lung; Catechin; Cell Line, Tumor; Down-Regulation; Epithelial-Mesenchymal Transition; Humans; Lung Neoplasms; MAP Kinase Signaling System; Plant Extracts; Smad2 Protein; Transforming Growth Factor beta | 2012 |
(-)-Epigallocatechin-3-gallate inhibits human papillomavirus (HPV)-16 oncoprotein-induced angiogenesis in non-small cell lung cancer cells by targeting HIF-1α.
Topics: Angiogenesis Inhibitors; Animals; Blotting, Western; Carcinoma, Non-Small-Cell Lung; Catechin; Cell Line, Tumor; Enzyme-Linked Immunosorbent Assay; Gene Expression; Human papillomavirus 16; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Interleukin-8; Lung Neoplasms; Male; Mice; Mice, Inbred BALB C; Neovascularization, Pathologic; Oncogene Proteins; Oncogene Proteins, Viral; Papillomavirus E7 Proteins; Platelet Endothelial Cell Adhesion Molecule-1; Proto-Oncogene Proteins c-akt; Real-Time Polymerase Chain Reaction; Repressor Proteins; Signal Transduction; Transfection; Vascular Endothelial Growth Factor A | 2013 |
Chemoprevention of lung carcinogenesis by cacao liquor proanthocyanidins in a male rat multi-organ carcinogenesis model.
Topics: 1,2-Dimethylhydrazine; Animals; Anthocyanins; Anticarcinogenic Agents; Butylhydroxybutylnitrosamine; Cacao; Carcinoma; Catechin; Diethylnitrosamine; Drug Administration Schedule; Drug Screening Assays, Antitumor; Flavonoids; Gastrointestinal Neoplasms; Injections, Intraperitoneal; Injections, Subcutaneous; Lung Neoplasms; Male; Methylnitrosourea; Neoplasms, Experimental; Nitrosamines; Organ Specificity; Phenols; Phytotherapy; Pituitary Neoplasms; Plant Extracts; Polymers; Proanthocyanidins; Rats; Rats, Inbred F344; Thyroid Neoplasms; Urogenital Neoplasms | 2003 |
Sulindac sulfide and caffeic acid phenethyl ester suppress the motility of lung adenocarcinoma cells promoted by transforming growth factor-beta through Akt inhibition.
Topics: Adenocarcinoma; Antineoplastic Agents; Caffeic Acids; Catechin; Cell Movement; Curcumin; Humans; Lung Neoplasms; Neovascularization, Pathologic; NF-kappa B; Phenylethyl Alcohol; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Sulindac; Transforming Growth Factor beta; Tumor Cells, Cultured | 2004 |
Activation of the Akt/nuclear factor-kappaB signaling axis in developing lung neoplasia.
Topics: Anticarcinogenic Agents; Budesonide; Catechin; Cell Line, Tumor; Eflornithine; Humans; Lung Neoplasms; Neoplasm Proteins; NF-kappa B; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt | 2004 |
Repressions of MMP-9 expression and NF-kappa B localization are involved in inhibition of lung carcinoma 95-D cell invasion by (-)-epigallocatechin-3-gallate.
Topics: Antioxidants; Blotting, Western; Catechin; Down-Regulation; Humans; Lung Neoplasms; Matrix Metalloproteinase Inhibitors; Neoplasm Metastasis; NF-kappa B; Reactive Oxygen Species; Reverse Transcriptase Polymerase Chain Reaction; Tumor Cells, Cultured | 2005 |
Black tea polyphenols suppress cell proliferation and induce apoptosis during benzo(a)pyrene-induced lung carcinogenesis.
Topics: Animals; Apoptosis; Benzo(a)pyrene; Biflavonoids; Carcinoma in Situ; Catechin; Cell Proliferation; Lung Neoplasms; Mice; Tea | 2005 |
Black tea extract can modulate protein expression of H-ras, c-Myc, p53, and Bcl-2 genes during pulmonary hyperplasia, dysplasia, and carcinoma in situ.
Topics: Animals; Animals, Newborn; Anticarcinogenic Agents; Apoptosis; Benzo(a)pyrene; Biflavonoids; Carcinoma in Situ; Catechin; Cell Proliferation; Disease Models, Animal; Female; Gene Expression Regulation, Neoplastic; Hyperplasia; Lung; Lung Neoplasms; Male; Mice; Plant Extracts; Proto-Oncogene Proteins; Proto-Oncogenes; Tea | 2005 |
Green tea polyphenol stimulates cancer preventive effects of celecoxib in human lung cancer cells by upregulation of GADD153 gene.
Topics: Anticarcinogenic Agents; Blotting, Western; Catechin; Celecoxib; Cell Line, Tumor; Cyclooxygenase Inhibitors; Drug Synergism; Flavonoids; Flow Cytometry; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; Mitogen-Activated Protein Kinase Kinases; Phenols; Plant Extracts; Polymerase Chain Reaction; Polyphenols; Pyrazoles; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sulfonamides; Tea; Transcription Factor CHOP; Up-Regulation | 2006 |
Efficacy of polyphenon E, red ginseng, and rapamycin on benzo(a)pyrene-induced lung tumorigenesis in A/J mice.
Topics: Adenoma; Animals; Antibiotics, Antineoplastic; Anticarcinogenic Agents; Antineoplastic Agents; Benzo(a)pyrene; Catechin; Female; Lung Neoplasms; Mice; Panax; Protein Kinases; Sirolimus; Tea; TOR Serine-Threonine Kinases | 2006 |
Differential alterations in metabolic pattern of the spliceosomal UsnRNAs during pre-malignant lung lesions induced by benzo(a)pyrene: modulation by tea polyphenols.
Topics: Animals; Benzo(a)pyrene; Catechin; Flavonoids; Lung; Lung Neoplasms; Mice; Phenols; Polyphenols; Precancerous Conditions; RNA, Small Nuclear; Spliceosomes; Tea | 2006 |
Constitutive overexpression of Nrf2-dependent heme oxygenase-1 in A549 cells contributes to resistance to apoptosis induced by epigallocatechin 3-gallate.
Topics: Adenocarcinoma; Antioxidants; Apoptosis; Catechin; Cell Line, Tumor; Cell Survival; Drug Resistance, Neoplasm; Gene Expression Regulation; Gene Expression Regulation, Neoplastic; Heme Oxygenase-1; Humans; Lung Neoplasms; NF-E2-Related Factor 2; Oxidation-Reduction; Protein Kinase C-alpha; Response Elements; RNA, Small Interfering; Sensitivity and Specificity; Transcriptional Activation | 2006 |
Inhibition of adenoma progression to adenocarcinoma in a 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-induced lung tumorigenesis model in A/J mice by tea polyphenols and caffeine.
Topics: Adenocarcinoma; Adenoma; Analysis of Variance; Animals; Caffeine; Catechin; Cell Proliferation; Disease Progression; Female; Flavonoids; Immunohistochemistry; JNK Mitogen-Activated Protein Kinases; Lung; Lung Neoplasms; Mice; Mice, Inbred Strains; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Nitrosamines; Phenols; Phosphorylation; Polyphenols; Proliferating Cell Nuclear Antigen; Tea; Time Factors | 2006 |
Synergistic effects of multiple treatments, and both DNA and RNA direct bindings on, green tea catechins.
Topics: Apoptosis; Camellia sinensis; Catechin; Cyclin-Dependent Kinase Inhibitor p21; DNA, Neoplasm; Drug Synergism; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; RNA, Neoplasm; Tea; Transcription Factor CHOP; Tumor Cells, Cultured | 2007 |
Chemopreventive effect of aerosolized polyphenon E on lung tumorigenesis in A/J mice.
Topics: Aerosols; Animals; Anticarcinogenic Agents; Benzo(a)pyrene; Catechin; Female; Lung Neoplasms; Mice | 2007 |
Inhibition of epigallocatechin gallate on orthotopic colon cancer by upregulating the Nrf2-UGT1A signal pathway in nude mice.
Topics: Animals; Anticarcinogenic Agents; Catechin; Colonic Neoplasms; Glucuronosyltransferase; HT29 Cells; Humans; Lung Neoplasms; Male; Mice; Mice, Inbred BALB C; Mice, Nude; NF-E2-Related Factor 2; RNA, Messenger; Signal Transduction | 2007 |
Epigallocatechin-3-gallate inhibits interleukin-1beta-induced MUC5AC gene expression and MUC5AC secretion in normal human nasal epithelial cells.
Topics: Catechin; Dose-Response Relationship, Drug; Enzyme Activation; Gene Expression; Humans; Interleukin-1beta; Lung Neoplasms; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mucin 5AC; Mucins; Nasal Mucosa; Promoter Regions, Genetic; Signal Transduction; Tumor Cells, Cultured | 2008 |
N-Acetylcysteine enhances the lung cancer inhibitory effect of epigallocatechin-3-gallate and forms a new adduct.
Topics: Acetylcysteine; Animals; Antineoplastic Combined Chemotherapy Protocols; Antioxidants; Apoptosis; Catechin; Cell Line, Tumor; Cell Proliferation; Chromatography, High Pressure Liquid; Flow Cytometry; Humans; Lung Neoplasms; Mice; Radiation-Protective Agents | 2008 |
Effects of catechins on the mouse tumor cell adhesion to fibronectin.
Topics: Animals; Binding Sites; Catechin; Cell Adhesion; Fibronectins; Lung Neoplasms; Melanoma, Experimental; Mice; Tumor Cells, Cultured | 1995 |
Inhibition of lung metastasis in mice induced by B16F10 melanoma cells by polyphenolic compounds.
Topics: Animals; Catechin; Cell Survival; Curcumin; Female; Flavonoids; Lung Neoplasms; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Neoplasm Metastasis; Phenols; Polymers; Rutin; Survival Analysis | 1995 |
Effects of green tea and black tea on 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone bioactivation, DNA methylation, and lung tumorigenesis in A/J mice.
Topics: Animals; Beverages; Carcinogens; Catechin; DNA; Female; Flavonoids; Lung; Lung Neoplasms; Methylation; Mice; Microsomes; Nitrosamines; Pyridines; Tea | 1994 |
Effects of catechins on the mouse lung carcinoma cell adhesion to the endothelial cells.
Topics: Animals; Catechin; Cattle; Cell Adhesion; Cell Survival; Cells, Cultured; Endothelium, Vascular; Flavonoids; Lung Neoplasms; Mice; Mice, Inbred C57BL; Structure-Activity Relationship; Tumor Cells, Cultured | 1993 |
Anticarcinogenic activity of green tea polyphenols.
Topics: Animals; Antineoplastic Agents; Catechin; Dose-Response Relationship, Drug; Doxorubicin; Estrogens; Flavonoids; Lung Neoplasms; Lyngbya Toxins; Mammary Neoplasms, Experimental; Phenols; Plant Extracts; Polymers; Protein Kinase C; Tea; Tumor Cells, Cultured | 1993 |
Effects of green tea catechins in a rat multi-organ carcinogenesis model.
Topics: 1,2-Dimethylhydrazine; Adenoma; Animals; Anticarcinogenic Agents; Body Weight; Butylhydroxybutylnitrosamine; Carcinogenicity Tests; Catechin; Cocarcinogenesis; Colonic Neoplasms; Dimethylhydrazines; Disease Models, Animal; Intestinal Neoplasms; Intestine, Small; Kidney Neoplasms; Liver Neoplasms, Experimental; Lung Neoplasms; Male; Models, Biological; Neoplasms, Experimental; Rats; Rats, Inbred F344 | 1993 |
Inhibitory effects of green tea infusion on in vitro invasion and in vivo metastasis of mouse lung carcinoma cells.
Topics: Animals; Antineoplastic Agents, Phytogenic; Basement Membrane; Catechin; Cell Membrane Permeability; Collagen; Drug Combinations; Laminin; Lung Neoplasms; Male; Membranes, Artificial; Mice; Mice, Inbred C57BL; Neoplasm Metastasis; Phytotherapy; Proteoglycans; Tea; Tumor Cells, Cultured | 1995 |
Mechanisms of growth inhibition of human lung cancer cell line, PC-9, by tea polyphenols.
Topics: Antineoplastic Agents; Catechin; Cell Cycle; Cell Division; Humans; Lung Neoplasms; Phenols; Tea; Tritium; Tumor Cells, Cultured | 1997 |
Inhibition of collagenases from mouse lung carcinoma cells by green tea catechins and black tea theaflavins.
Topics: Animals; Antioxidants; Biflavonoids; Carcinoma; Catechin; Free Radical Scavengers; Gallic Acid; Lung Neoplasms; Matrix Metalloproteinase Inhibitors; Mice; Tea; Tumor Cells, Cultured | 1997 |
Black tea constituents, theaflavins, inhibit 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK)-induced lung tumorigenesis in A/J mice.
Topics: Animals; Antineoplastic Agents; Biflavonoids; Body Weight; Bromodeoxyuridine; Carcinogens; Catechin; Cell Division; Chemoprevention; Female; Hyperplasia; Lung Neoplasms; Mice; Mice, Inbred A; Nitrosamines; Tea; Vitamin A; Vitamin E | 1997 |
Inhibition of growth and induction of apoptosis in human cancer cell lines by tea polyphenols.
Topics: Adenocarcinoma; Anticarcinogenic Agents; Apoptosis; Catechin; Cell Division; Colonic Neoplasms; Humans; Lung Neoplasms; Superoxide Dismutase; Tea; Tumor Cells, Cultured | 1998 |
Interaction between the carboxyl-terminal heparin-binding domain of fibronectin and (-)-epigallocatechin gallate.
Topics: Antineoplastic Agents; Catechin; Cell Adhesion; Fibronectins; Humans; Lung Neoplasms | 1998 |
Nitro-polycyclic aromatic hydrocarbon contents of fumes from heated cooking oils and prevention of mutagenicity by catechin.
Topics: Antimutagenic Agents; Antioxidants; Arachis; Catechin; Dietary Fats; Female; Hot Temperature; Humans; Lung Neoplasms; Mutagenicity Tests; Mutagens; Oils; Peanut Oil; Plant Oils; Polycyclic Aromatic Hydrocarbons; Salmonella typhimurium; Soybean Oil; Taiwan | 1998 |
Synergistic effects of (--)-epigallocatechin gallate with (--)-epicatechin, sulindac, or tamoxifen on cancer-preventive activity in the human lung cancer cell line PC-9.
Topics: 3T3 Cells; Animals; Anticarcinogenic Agents; Apoptosis; Catechin; Cell Division; Dose-Response Relationship, Drug; Drug Synergism; Humans; Lung Neoplasms; Mice; Sulindac; Tamoxifen; Tea; Tumor Cells, Cultured | 1999 |
Anti-metastatic activity of curcumin and catechin.
Topics: Animals; Antineoplastic Agents; Catechin; Cell Adhesion; Cell Movement; Collagen; Curcumin; Female; Gelatin; Hydroxyproline; Lung Neoplasms; Melanoma, Experimental; Mice; Mice, Inbred C57BL; N-Acetylneuraminic Acid; Neoplasm Invasiveness; Neoplasm Metastasis; Neoplasm Transplantation; Survival Rate; Tumor Cells, Cultured | 1999 |
(-)-Epigallocatechin gallate can prevent cisplatin-induced lung tumorigenesis in A/J mice.
Topics: Animals; Anticarcinogenic Agents; Catechin; Cisplatin; Female; Lung Neoplasms; Mice | 2000 |
Flavonoids apigenin and quercetin inhibit melanoma growth and metastatic potential.
Topics: Animals; Anticarcinogenic Agents; Apigenin; Catechin; Cell Division; Curcumin; Female; Flavonoids; Growth Inhibitors; Lung Neoplasms; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Neoplasm Invasiveness; Neoplasm Transplantation; Quercetin; Resveratrol; Stilbenes; Tamoxifen; Tumor Cells, Cultured | 2000 |
Dietary catechins and epithelial cancer incidence: the Zutphen elderly study.
Topics: Aged; Carcinoma; Catechin; Cohort Studies; Diet; Humans; Incidence; Lung Neoplasms; Male; Odds Ratio; Prospective Studies; Risk Factors; Rosales; Tea | 2001 |
Green tea catechins enhance tumor development in the colon without effects in the lung or thyroid after pretreatment with 1,2-Dimethylhydrazine or 2,2'-dihydroxy-di-n-propylnitrosamine in male F344 rats.
Topics: 1,2-Dimethylhydrazine; Adenoma; Animals; Body Weight; Carcinogens; Carcinoma; Catechin; Colonic Neoplasms; Lung Neoplasms; Male; Nitrosamines; Organ Size; Phytotherapy; Rats; Rats, Inbred F344; Tea; Thyroid Neoplasms | 2001 |
Modulation of gene expression by (-)-epigallocatechin gallate in PC-9 cells using a cDNA expression array.
Topics: Antimutagenic Agents; Catechin; DNA Probes; DNA, Complementary; Down-Regulation; Gene Expression; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; NF-kappa B; Oligonucleotide Array Sequence Analysis; Poly A; Reverse Transcriptase Polymerase Chain Reaction; Tumor Cells, Cultured; Up-Regulation | 2001 |
Inhibition of melanoma growth and metastasis by combination with (-)-epigallocatechin-3-gallate and dacarbazine in mice.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Catechin; Cell Aggregation; Cell Communication; Cell Movement; Cell Transformation, Neoplastic; Dacarbazine; Drug Screening Assays, Antitumor; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Growth Inhibitors; Injections, Intraperitoneal; Lung Neoplasms; Male; Matrix Metalloproteinases; Melanoma, Experimental; Mice; Neoplasm Transplantation; Phosphorylation; Protein-Tyrosine Kinases; Survival Rate; Tea; Tumor Cells, Cultured; Tumor Stem Cell Assay; Tyrosine | 2001 |
Lung cancer prevention with (-)-epigallocatechin gallate using monitoring by heterogeneous nuclear ribonucleoprotein B1.
Topics: Antineoplastic Agents, Phytogenic; Biomarkers, Tumor; Catechin; Cell Cycle; Gene Expression Regulation; Genistein; Heterogeneous-Nuclear Ribonucleoprotein Group A-B; Heterogeneous-Nuclear Ribonucleoproteins; Humans; Lung Neoplasms; Ribonucleoproteins; RNA, Messenger; Tea; Transcription, Genetic; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 2002 |
Effect of (-)-epigallocatechin gallate, the main constituent of green tea, on lung metastasis with mouse B16 melanoma cell lines.
Topics: Animals; Catechin; Flavonoids; Lung Neoplasms; Male; Melanoma; Mice; Mice, Inbred C57BL; Neoplasm Transplantation; Tumor Cells, Cultured | 1992 |
Inhibition of tobacco-specific nitrosamine-induced lung tumorigenesis in A/J mice by green tea and its major polyphenol as antioxidants.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Caffeine; Carcinogens; Catechin; Deoxyguanosine; DNA; Female; Guanine; Liver; Lung; Lung Neoplasms; Mice; Mice, Inbred A; Nitrosamines; Tea | 1992 |