catechin has been researched along with Liver Neoplasms in 96 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (1.04) | 18.7374 |
| 1990's | 4 (4.17) | 18.2507 |
| 2000's | 33 (34.38) | 29.6817 |
| 2010's | 48 (50.00) | 24.3611 |
| 2020's | 10 (10.42) | 2.80 |
| Authors | Studies |
|---|---|
| Cai, X; Chen, D; Chen, P; He, X; Hong, Y; Liu, H; Shen, X; Wang, Q; Wang, Y; Zhao, J | 1 |
| Chen, D; Guan, Y; Li, M; Li, Y; Su, J; Wu, Q; Zhu, B; Zuo, L | 1 |
| Ene, AG; Ficai, A; Ficai, D; Vladu, AF | 1 |
| Jin, J; Sun, H; Wang, M; Yang, H; Zhu, S | 1 |
| Bajaj, S; Bansal, H; Fayaz, F; Kumar, S; Manchanda, S; Pottoo, FH | 1 |
| An, H; Chen, Y; Ma, B; Na, W; Shi, S; Zhan, Y; Zhang, H | 1 |
| Chen, YY; Fu, LX; Gan, RZ; Li, L; Liang, G; Lv, MX; Zhang, XX; Zhou, H; Zhou, JL; Zhu, HQ | 1 |
| An, H; Cai, Z; Cao, J; Chen, N; Li, K; Li, Y; Luo, A; Peng, Y; Tang, Y; Tao, H | 1 |
| Fahmi, AA; Gamal-Eldeen, AM; Maksoud, NAE; Mostafa, SM | 1 |
| Hu, D; Jiang, X; Li, J; Li, Z; Luo, Y; Shang, L; Shen, Y; Yang, C; Zhang, Z | 1 |
| Chen, F; Cheng, KW; Gowd, V; Kang, Q; Tong, Y; Wang, M | 1 |
| Chen, H; Chen, Z; Liu, W; Wang, J | 1 |
| Chen, C; Chen, J; Li, D; Li, M; Xu, X; Yin, Y; Zhan, R; Zhang, Q | 1 |
| Chen, ZS; Fu, LX; Gupta, P; Liang, G; Liu, BM; Tang, AZ; Wen, Y; Yang, DH; Zhang, YK; Zhao, RQ | 1 |
| Abdelaziz, AI; Assal, RA; El Tayebi, HM; El-Khatib, AH; Handoussa, H; Linscheid, MW; Shaalan, YM; Youness, RA | 1 |
| Goto, H; Hayashi, K; Ishida, K; Ishikawa, T; Koide, R; Satonaka, H; Shigemasa, R; Takai, M; Ueyama, J; Wakusawa, S | 1 |
| Amiel, A; Bourdy, G; Chassagne, F; Deharo, E; Haddad, M; Manithip, C; Marti, G; Phakeovilay, C | 1 |
| Li, H; Pu, H; Sun, Q; Tang, B; Tang, P; Yang, H | 1 |
| Abdel-Hameed, ND; Abdelaleem, OO; El Amin Ali, AM; Hassouna, A; Khalifa, WA; Mohammed, RA; Sabry, D | 1 |
| Albino, V; Bimonte, S; Cascella, M; Molino, C; Nasto, A; Palaia, R; Piccirillo, M | 1 |
| Bishayee, A; Darvesh, AS | 1 |
| Ahmed, A; Duan, W; Jiang, T; Owusu, L; Xin, Y; Zang, S; Zhang, Y | 1 |
| Baba, A; Kochi, T; Kubota, M; Moriwaki, H; Ohno, T; Shimizu, M; Shirakami, Y; Tanaka, T; Terakura, D; Tsurumi, H | 1 |
| Hashimoto, O; Hiroshi, M; Inoue, K; Iwamoto, H; Nakamura, A; Nakamura, T; Sata, M; Torimura, T; Ueno, T | 1 |
| Deng, C; Guo, T; Li, Y; Ren, X; Wang, Y; Xu, MX; Yan, E; Yang, L | 1 |
| Fukunaga, K; Maruyama, T; Murata, S; Nakayama, K; Nowatari, T; Nozaki, R; Ogawa, K; Ohkohchi, N; Sano, N; Tamura, T | 1 |
| Feng, Y; Li, J; Luo, X; Shen, X; Xie, YA; Zhang, L; Zhang, Y | 1 |
| Chen, L; Chen, XZ; Liang, G; Yao, WM; Ye, HL; Zhang, FC; Zhang, G | 1 |
| Feng, LL; Liu, BX; Sun, LB; Yu, HS; Zhong, JY | 1 |
| Abbas, A; Al-Gayyar, MM; Darweish, MM; Ebrahim, MA | 1 |
| Butler, LM; Gao, YT; Huang, JY; Lee, MJ; Wang, R; Yang, CS; Yuan, JM | 1 |
| Ideta, T; Kochi, T; Kubota, M; Miyazaki, T; Moriwaki, H; Sakai, H; Shimizu, M; Shirakami, Y | 1 |
| Ho, CT; Lai, CS; Lee, YL; Li, S; Pan, MH; Tsai, CY; Wan, X; Weerawatanakorn, M | 1 |
| Gao, B; Hu, J; Shu, W; Xiong, S; Zhong, L | 1 |
| Altoparlak, U; Aydogdu, S; Gundogdu, C; Karamese, M; Karamese, SA | 1 |
| Ahmad, A; Farhan, M; Hadi, SM; Naseem, I; Rizvi, A | 1 |
| Arffa, ML; Driver, J; Gupta, GN; Kothari, AN; Kuo, PC; Mi, Z; Wai, PY; Weber, CE; Zapf, MA | 1 |
| Arakawa, Y; Ikemoto, T; Imura, S; Ishikawa, D; Iwahashi, S; Morine, Y; Saito, Y; Shimada, M; Wubetu, GY; Yamada, S | 1 |
| Chang, JB; Ho, CT; Liu, JJ; Liu, TZ; Shang, HS | 1 |
| Sakai, H; Shimizu, M; Shirakami, Y | 1 |
| Barua, A; Pal, D; Panda, CK; Roy, A; Roy, R; Saha, P; Sur, S | 1 |
| Chen, K; Cheng, K; Dai, W; Feng, J; Guo, C; Kong, R; Li, J; Li, S; Liu, T; Lu, J; Wang, F; Wu, L; Xia, Y; Xu, S; Zhang, R; Zhou, S; Zhou, Y | 1 |
| Liang, G; Tang, HH; Zhou, M | 1 |
| Berry, DP; Dennison, AR; Garcea, G; Mann, CD; Manson, MM; Neal, CP | 1 |
| Cao, LQ; Chen, JS; Chen, XL; Fu, XH; Huang, XH; Tan, HX; Wang, Q; Zhen, MC | 1 |
| Kwok, TT; Tsang, WP | 1 |
| Henklein, P; Kaufmann, R; Settmacher, U | 1 |
| Haramizu, S; Hase, T; Misawa, K; Murase, T | 1 |
| Adachi, S; Hara, Y; Moriwaki, H; Nakagawa, T; Sakai, H; Shimizu, M; Shirakami, Y; Tsurumi, H; Yasuda, Y | 1 |
| Li, W; Nie, S; Xie, M; Yu, Q | 1 |
| Im, HG; Kim, HI; Lee, IS; Yu, MH | 1 |
| Delgado, ME; García, A; Haza, AI; Morales, P | 1 |
| Huang, CH; Kao, JY; Pan, MH; Tsai, SJ; Wang, YJ; Way, TD | 1 |
| Abe, K; Kamei, A; Kiso, Y; Kitagawa, Y; Misaka, T; Negishi, M; Sueyoshi, T; Tateishi, N; Tsuruoka, N; Yao, R; Yasuoka, A | 1 |
| He, M; Wang, X; Wei, X; Zhang, Z; Zheng, W | 1 |
| Ardèvol, A; Arola, L; Bladé, C; Blay, M; Bustos, M; Fernández-Larrea, J; Pujadas, G; Quesada, IM; Salvadó, MJ | 1 |
| Dang, Y; Ding, L; Hu, H; Hu, X; Huang, Q; Huang, W; Ji, X; Jiang, S; Li, J; Liu, JO; Liu, S; Shen, S; Yang, X; Yu, L | 1 |
| Khaoustov, V; Yoffe, B | 1 |
| Popovich, DG; Tiaras, F; Yeo, CR; Zhang, W | 1 |
| Huo, X; Jiang, Y; Li, M; Luo, T; Sun, X; Yin, Y | 1 |
| Bardag-Gorce, F; French, SW; Oliva, J; Tillman, B | 1 |
| Baba, A; Hara, Y; Kubota, M; Moriwaki, H; Ohno, T; Sakai, H; Shimizu, M; Shirakami, Y; Tanaka, T; Terakura, D; Yasuda, Y | 1 |
| Chan, V; Chen, B; Chen, WN; Feng, H; Li, X; Ng, SS | 1 |
| Asano, K; Haneishi, A; Nakamura, S; Noguchi, T; Takagi, K; Tanaka, T; Yamada, K; Yamamoto, T | 1 |
| Kubota, M; Moriwaki, H; Shimizu, M; Tanaka, T | 1 |
| Chang, Y; He, YF; Hu, SS; Jin, J; Wang, D; Wei, W; Wu, YJ | 1 |
| Landim, JS; Mota, MA; Pereira, MR; Ponte, MF; Ribeiro, TR; Silva, SF; Silva, SL; Soares, FP; Targino, TS | 1 |
| Abou El Naga, RN; Ammar, el-SM; Azab, SS; El-Demerdash, E; El-Merzabani, M; Shaarawy, S | 1 |
| Hirakawa, Y; Inui, H; Murakami, C; Nakano, Y; Yoshida, H | 1 |
| Dauer, A; Hensel, A; Knasmüller, S; Lhoste, E; Mersch-Sundermann, V | 1 |
| Nakamura, T; Sakamoto, M; Sakata, R; Sata, M; Torimura, T; Ueno, T | 1 |
| Liu, JW; Tong, WY; Wei, DZ; Yang, JY | 1 |
| Huang, ZM; Liang, G; Tang, AZ; Zhang, S | 1 |
| Tang, AB; Tu, YY; Watanabe, N | 1 |
| Alía, M; Bravo, L; Goya, L; Ramos, S | 1 |
| Billam, M; Huang, T; Liang, Y; Luo, H; Tang, L; Tang, M; Wang, JS; Wang, K; Wei, Z; Yu, J; Zhang, L; Zhang, ZQ | 1 |
| Cui, YY; He, YM; Qi, KB; Wang, JF; Xie, H | 1 |
| Bae, JH; Chung, JH; Chung, WJ; Hong, MS; Hwang, JS; Leem, K; Park, HJ; Shin, DH; Yoon, SH | 1 |
| Ishii, M; Itoh, Y; Jo, M; Kagawa, K; Katagishi, T; Kimura, H; Minami, M; Moriguchi, M; Nakajima, T; Nishikawa, T; Okanoue, T; Sekoguchi, S; Takashima, H | 1 |
| Le, AD; Lu, Q; Rao, J; Tang, X; Zhang, Q; Zhang, Z | 1 |
| Ling, MT; Wang, X; Wong, YC; Zhang, X | 1 |
| Friedman, M; Kim, HJ; Kozukue, E; Kozukue, N; Lee, IS; Lee, KR; Lee, SU; Mackey, BE | 1 |
| Bravo, L; Goya, L; Granado-Serrano, AB; Izquierdo-Pulido, M; Martín, MA; Ramos, S | 1 |
| Konta, L; Révész, K; Tüttô, A | 1 |
| Hara, Y; Moriwaki, H; Nakagawa, T; Sakai, H; Shimizu, M; Shirakami, Y; Tatebe, H; Weinstein, IB | 1 |
| Boo, YC; Kim, HJ; Lee, SI | 1 |
| Liu, HM; Lu, L; Tang, WX | 1 |
| Angeles Martín, M; Bravo, L; Goya, L; Granado-Serrano, AB; Ramos, S | 1 |
| Lin, CL; Lin, JK | 1 |
| Fukutomi, Y; Moriwaki, H; Muto, Y; Ninomiya, M; Nishida, H; Nishiwaki, S; Omori, M; Suganuma, M | 1 |
| Futakuchi, M; Hirose, M; Iwata, H; Ogawa, K; Shibutani, M; Shirai, T; Takahashi, S; Toyoda, K; Uneyama, C | 1 |
| Brackney, W; Denison, MS; Guenette, DK; Pickwell, GV; Quattrochi, LC; Shih, H; Williams, SN | 1 |
| Hori, H; Kamishimoto, M; Kitagawa, Y; Kumagai, A; Nagasawa, H; Uesato, S | 1 |
| Klaunig, JE | 1 |
| Ding, LA | 1 |
| Hacobian, N; Ho, LL; Lotlikar, PD; Magee, PN; Prasanna, HR | 1 |
9 review(s) available for catechin and Liver Neoplasms
| Article | Year |
|---|---|
Combination Therapy Using Polyphenols: An Efficient Way to Improve Antitumoral Activity and Reduce Resistance.
Topics: Anti-Bacterial Agents; Antineoplastic Agents; beta Catenin; Breast Neoplasms; Catechin; Curcumin; Cytostatic Agents; Doxorubicin; Estrogen Receptor alpha; Estrogen Receptor beta; Estrogens; Female; Fluorouracil; Humans; Liver Neoplasms; Polyphenols; Receptors, Estrogen; Resveratrol | 2022 |
Nanophytomedicine Based Novel Therapeutic Strategies in Liver Cancer.
Topics: Antineoplastic Agents, Phytogenic; Carcinoma, Hepatocellular; Catechin; Curcumin; Drug Compounding; Drug Stability; Humans; Liver Neoplasms; Nanocapsules; Plant Extracts; Quercetin; Resveratrol; Solubility; Theranostic Nanomedicine | 2020 |
Epigallocatechin-3-gallate in the prevention and treatment of hepatocellular carcinoma: experimental findings and translational perspectives.
Topics: Animals; Carcinoma, Hepatocellular; Catechin; Humans; Liver Neoplasms | 2019 |
Chemopreventive and therapeutic potential of tea polyphenols in hepatocellular cancer.
Topics: Animals; Anti-Inflammatory Agents; Anticarcinogenic Agents; Antioxidants; Biological Availability; Catechin; Chemoprevention; Disease Models, Animal; Humans; Liver Neoplasms; Mice; Polyphenols; Tea; Xenograft Model Antitumor Assays | 2013 |
Chemopreventive potential of green tea catechins in hepatocellular carcinoma.
Topics: Animals; Carcinoma, Hepatocellular; Catechin; Chemoprevention; Clinical Trials as Topic; Humans; Liver Neoplasms; Metabolic Diseases; Obesity; Tea | 2015 |
Chemoprevention of obesity-related liver carcinogenesis by using pharmaceutical and nutraceutical agents.
Topics: Amino Acids, Branched-Chain; Animals; Carcinoma, Hepatocellular; Catechin; Chemoprevention; Diabetes Mellitus, Experimental; Dietary Supplements; Humans; Liver Neoplasms; Mice; Non-alcoholic Fatty Liver Disease; Obesity; Tea; Tretinoin | 2016 |
Phytochemicals as potential chemopreventive and chemotherapeutic agents in hepatocarcinogenesis.
Topics: Animals; Antineoplastic Agents, Phytogenic; Brassicaceae; Caffeine; Capsaicin; Carcinoma, Hepatocellular; Catechin; Chemoprevention; Curcumin; Flavonoids; Humans; Liver Neoplasms; Phenols; Plant Extracts; Polyphenols; Resveratrol; Stilbenes | 2009 |
Nutraceutical approach for preventing obesity-related colorectal and liver carcinogenesis.
Topics: Amino Acids, Branched-Chain; Carcinogenesis; Catechin; Colorectal Neoplasms; Cytokines; Dietary Supplements; Humans; Liver Neoplasms; Obesity; Risk Factors | 2012 |
[Effect of green tea flavonols on the function of the endoplasmic reticulum].
Topics: alpha-Glucosidases; Animals; Antineoplastic Agents; Apoptosis; Blood Glucose; Carcinoma, Hepatocellular; Catechin; Cell Line, Tumor; Endoplasmic Reticulum; Flavonols; Glucuronides; Glycoside Hydrolase Inhibitors; Humans; Hypoglycemic Agents; Liver; Liver Neoplasms; Microsomes; Tea | 2007 |
1 trial(s) available for catechin and Liver Neoplasms
| Article | Year |
|---|---|
Phase IIa chemoprevention trial of green tea polyphenols in high-risk individuals of liver cancer: modulation of urinary excretion of green tea polyphenols and 8-hydroxydeoxyguanosine.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Adult; Biomarkers; Catechin; Chemoprevention; Deoxyguanosine; DNA Damage; Dose-Response Relationship, Drug; Double-Blind Method; Female; Flavonoids; Humans; Liver Neoplasms; Male; Oxidative Stress; Phenols; Polyphenols; Risk Factors; Tea | 2006 |
86 other study(ies) available for catechin and Liver Neoplasms
| Article | Year |
|---|---|
The Invasive Potential of Hepatoma Cells Induced by Radiotherapy is Related to the Activation of Hepatic Stellate Cells and Could be Inhibited by EGCG Through the TLR4 Signaling Pathway.
Topics: Animals; Carcinoma, Hepatocellular; Catechin; Cell Line, Tumor; Hepatic Stellate Cells; Interleukin-6; Liver Neoplasms; Mice; Signal Transduction; Toll-Like Receptor 4; Tumor Microenvironment | 2022 |
Epigallocatechin-3-gallate Induced HepG2 Cells Apoptosis through ROSmediated AKT /JNK and p53 Signaling Pathway.
Topics: Antineoplastic Agents; Apoptosis; Catechin; Hep G2 Cells; Humans; Liver Neoplasms; Proto-Oncogene Proteins c-akt; Reactive Oxygen Species; Signal Transduction; Tumor Suppressor Protein p53 | 2023 |
Synergetic Effect of EP1 Receptor Antagonist and (-)-Epigallocatechin-3-gallate in Hepatocellular Carcinoma.
Topics: Alprostadil; Apoptosis; Carcinoma, Hepatocellular; Catechin; Cell Movement; Cell Proliferation; Dinoprostone; Drug Synergism; Hep G2 Cells; Humans; Liver Neoplasms; Receptors, Prostaglandin E, EP1 Subtype; Wound Healing | 2019 |
Procyanidin B1, a novel and specific inhibitor of Kv10.1 channel, suppresses the evolution of hepatoma.
Topics: Animals; Biflavonoids; Carcinogenesis; Carcinoma, Hepatocellular; Catechin; Ether-A-Go-Go Potassium Channels; HEK293 Cells; Hep G2 Cells; Humans; Liver Neoplasms; Male; Mice; Mice, Inbred BALB C; Proanthocyanidins; Protein Structure, Secondary; Protein Structure, Tertiary; Tumor Burden; Xenograft Model Antitumor Assays | 2020 |
The epigallocatechin gallate derivative Y6 reduces the cardiotoxicity and enhances the efficacy of daunorubicin against human hepatocellular carcinoma by inhibiting carbonyl reductase 1 expression.
Topics: Alcohol Oxidoreductases; Animals; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Arrhythmias, Cardiac; Carcinoma, Hepatocellular; Cardiotoxicity; Catechin; Cell Proliferation; Daunorubicin; Drug Synergism; Enzyme Inhibitors; Female; Gene Expression Regulation, Neoplastic; Heart Rate; Hep G2 Cells; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Liver Neoplasms; Male; Mice, Inbred BALB C; Mice, Nude; Signal Transduction; Tumor Burden; Xenograft Model Antitumor Assays | 2020 |
Epigallocatechin gallate induces chemopreventive effects on rats with diethylnitrosamine‑induced liver cancer via inhibition of cell division cycle 25A.
Topics: Animals; Antineoplastic Agents, Phytogenic; Carcinoma, Hepatocellular; Catechin; cdc25 Phosphatases; Cell Cycle; Cell Proliferation; Cell Survival; Diethylnitrosamine; Disease Models, Animal; Hep G2 Cells; Humans; Liver; Liver Neoplasms; Male; Phytotherapy; Plant Extracts; Rats; Rats, Sprague-Dawley; Tea; Transfection; Tumor Burden | 2020 |
Epigallocatechin gallate-capped gold nanoparticles enhanced the tumor suppressors let-7a and miR-34a in hepatocellular carcinoma cells.
Topics: Carcinoma, Hepatocellular; Catechin; Gold; Humans; Liver Neoplasms; Metal Nanoparticles; MicroRNAs | 2020 |
L-EGCG-Mn nanoparticles as a pH-sensitive MRI contrast agent.
Topics: Animals; Carcinoma, Hepatocellular; Catechin; Cell Line, Tumor; Contrast Media; Gadolinium DTPA; Hydrogen-Ion Concentration; Liver Neoplasms; Magnetic Resonance Imaging; Manganese; Mice; Nanoparticles; Peritoneal Neoplasms; Proof of Concept Study | 2021 |
Oral administration of EGCG solution equivalent to daily achievable dosages of regular tea drinkers effectively suppresses miR483-3p induced metastasis of hepatocellular carcinoma cells in mice.
Topics: Animals; Carcinoma, Hepatocellular; Catechin; Cell Line, Tumor; Female; Gene Expression Regulation, Neoplastic; Hep G2 Cells; Humans; Liver Neoplasms; Mice; Mice, Inbred BALB C; Mice, Nude; MicroRNAs; Neoplasm Metastasis; Reactive Oxygen Species; Solutions; Tea; Transduction, Genetic | 2021 |
Physicochemical characterization of the oolong tea polysaccharides with high molecular weight and their synergistic effects in combination with polyphenols on hepatocellular carcinoma.
Topics: Animals; Antioxidants; Carcinoma, Hepatocellular; Catechin; Cell Line, Tumor; Cell Proliferation; Drug Synergism; Humans; Liver Neoplasms; Male; Mice; Molecular Weight; Plant Extracts; Polyphenols; Polysaccharides; Tea | 2017 |
Cell surface GRP78 facilitates hepatoma cells proliferation and migration by activating IGF-IR.
Topics: Animals; Carcinoma, Hepatocellular; Catechin; Cell Movement; Cell Proliferation; Endoplasmic Reticulum; Endoplasmic Reticulum Chaperone BiP; Heat-Shock Proteins; Hep G2 Cells; Humans; Insulin-Like Growth Factor I; Liver Neoplasms; Phosphatidylinositol 3-Kinases; Phosphorylation; Proto-Oncogene Proteins c-akt; Receptor, IGF Type 1; Receptors, Somatomedin; Signal Transduction | 2017 |
Effect of Y6, an epigallocatechin gallate derivative, on reversing doxorubicin drug resistance in human hepatocellular carcinoma cells.
Topics: Antineoplastic Agents; Apoptosis; ATP Binding Cassette Transporter, Subfamily B, Member 1; Carcinoma, Hepatocellular; Catechin; Cell Line, Tumor; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Doxorubicin; Drug Resistance, Neoplasm; Gene Expression; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Liver Neoplasms | 2017 |
Destabilizing the interplay between miR-1275 and IGF2BPs by Tamarix articulata and quercetin in hepatocellular carcinoma.
Topics: Carcinoma, Hepatocellular; Catechin; Cell Line, Tumor; Cell Survival; Humans; Insulin-Like Growth Factor Binding Protein 2; Liver Neoplasms; MicroRNAs; Quercetin; Tamaricaceae | 2018 |
(-)-Epigallocatechin-3-gallate Down-regulates Doxorubicin-induced Overexpression of P-glycoprotein Through the Coordinate Inhibition of PI3K/Akt and MEK/ERK Signaling Pathways.
Topics: Antibiotics, Antineoplastic; ATP Binding Cassette Transporter, Subfamily B; Carcinoma, Hepatocellular; Catechin; Doxorubicin; Gene Expression Regulation, Neoplastic; Humans; Liver Neoplasms; MAP Kinase Signaling System; Neuroprotective Agents; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Proto-Oncogene Proteins c-akt; Rhodamine 123; Signal Transduction; Tumor Cells, Cultured | 2017 |
A metabolomic approach to identify anti-hepatocarcinogenic compounds from plants used traditionally in the treatment of liver diseases.
Topics: Andrographis; Antineoplastic Agents, Phytogenic; Apigenin; Apocynaceae; Asia, Southeastern; Biflavonoids; Bignoniaceae; Catechin; Diterpenes; Ethnopharmacology; Flavanones; Flavonoids; Hep G2 Cells; Humans; Lamiaceae; Liver Neoplasms; Metabolomics; Plants, Medicinal; Proanthocyanidins | 2018 |
Honokiol nanoparticles based on epigallocatechin gallate functionalized chitin to enhance therapeutic effects against liver cancer.
Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Biphenyl Compounds; Carcinoma, Hepatocellular; Catechin; Cell Proliferation; Chitin; Cross-Linking Reagents; Dose-Response Relationship, Drug; Drug Carriers; Drug Compounding; Drug Liberation; G2 Phase Cell Cycle Checkpoints; Hep G2 Cells; Humans; Kinetics; Lignans; Liver Neoplasms; Male; Membrane Potential, Mitochondrial; Mice, Inbred BALB C; Nanoparticles; Nanotechnology; Particle Size; Solubility; Surface Properties; Technology, Pharmaceutical; Tumor Burden; Xenograft Model Antitumor Assays | 2018 |
Anti-proliferative and anti-apoptotic potential effects of epigallocatechin-3-gallate and/or metformin on hepatocellular carcinoma cells: in vitro study.
Topics: Anticarcinogenic Agents; Apoptosis; Carcinoma, Hepatocellular; Caspase 3; Catechin; Cell Line, Tumor; Cell Proliferation; Cyclin D1; Glypicans; Hep G2 Cells; Humans; Liver Neoplasms; Metformin; RNA, Long Noncoding; Signal Transduction; Survivin; Vascular Endothelial Growth Factor A | 2019 |
Anti-metastatic and differential effects on protein expression of epigallocatechin-3-gallate in HCCLM6 hepatocellular carcinoma cells.
Topics: Antineoplastic Agents; Apoptosis; Carcinoma, Hepatocellular; Catechin; Cell Differentiation; Cell Line, Tumor; Cell Survival; DNA Helicases; DNA-Binding Proteins; Heat-Shock Proteins; HSP27 Heat-Shock Proteins; Humans; Liver Neoplasms; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Molecular Chaperones; Neoplasm Metastasis; Nuclear Proteins; Nucleophosmin; Protein Processing, Post-Translational; Proteomics; RNA-Binding Proteins | 2013 |
Non-alcoholic steatohepatitis and preneoplastic lesions develop in the liver of obese and hypertensive rats: suppressing effects of EGCG on the development of liver lesions.
Topics: Angiotensin II; Animals; Anticarcinogenic Agents; Catechin; Fatty Liver; Gene Expression; Hypertension; Interleukin-6; Lipid Peroxidation; Liver; Liver Cirrhosis; Liver Neoplasms; Male; Non-alcoholic Fatty Liver Disease; Obesity; Oxidative Stress; Peptidyl-Dipeptidase A; Precancerous Conditions; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptor, Angiotensin, Type 1; Tumor Necrosis Factor-alpha | 2014 |
Methylated-(3'')-epigallocatechin gallate analog suppresses tumor growth in Huh7 hepatoma cells via inhibition of angiogenesis.
Topics: Animals; Antioxidants; Carcinoma, Hepatocellular; Catechin; Cell Line, Tumor; Cell Proliferation; Cell Survival; Human Umbilical Vein Endothelial Cells; Humans; Liver Neoplasms; Mice; Mitogen-Activated Protein Kinase 1; Neovascularization, Pathologic; Vascular Endothelial Growth Factor A; Xenograft Model Antitumor Assays | 2014 |
Mechanism of the inhibition of the STAT3 signaling pathway by EGCG.
Topics: Apoptosis; Carcinoma, Hepatocellular; Catechin; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Survival; Gene Expression Regulation, Neoplastic; Humans; Liver Neoplasms; Molecular Docking Simulation; Phosphorylation; Protein Conformation; Signal Transduction; src Homology Domains; STAT3 Transcription Factor; Surface Plasmon Resonance; Tea | 2013 |
(-)-Epigallocatechin-3-gallate suppresses liver metastasis of human colorectal cancer.
Topics: Animals; Anticarcinogenic Agents; Antioxidants; Apoptosis; Catechin; Cell Line, Tumor; Cell Proliferation; Cell Survival; Colorectal Neoplasms; Enzyme Activation; HCT116 Cells; Humans; Liver Neoplasms; Male; Mice; Mice, SCID; Neovascularization, Pathologic; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Proto-Oncogene Proteins c-akt; Vascular Endothelial Growth Factor Receptor-2 | 2014 |
Epigallocatechin-3-gallate inhibits cell growth, induces apoptosis and causes S phase arrest in hepatocellular carcinoma by suppressing the AKT pathway.
Topics: Apoptosis; Carcinoma, Hepatocellular; Catechin; Cell Cycle Checkpoints; Cell Proliferation; Humans; Liver Neoplasms; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; S Phase; Signal Transduction | 2014 |
Autophagy inhibition contributes to the synergistic interaction between EGCG and doxorubicin to kill the hepatoma Hep3B cells.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Autophagy; Carcinoma, Hepatocellular; Catechin; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Doxorubicin; Drug Synergism; Humans; Liver Neoplasms; Mice; Mice, Nude; Up-Regulation; Xenograft Model Antitumor Assays | 2014 |
Effect of grape procyanidins on tumor angiogenesis in liver cancer xenograft models.
Topics: Animals; Antioxidants; Biflavonoids; Carcinoma, Hepatocellular; Catechin; Humans; Immunoenzyme Techniques; Liver Neoplasms; Mice; Neovascularization, Pathologic; Phytotherapy; Proanthocyanidins; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tumor Cells, Cultured; Vascular Endothelial Growth Factor A; Vitis; Xenograft Model Antitumor Assays | 2014 |
Chemopreventive and hepatoprotective effects of Epigallocatechin-gallate against hepatocellular carcinoma: role of heparan sulfate proteoglycans pathway.
Topics: alpha-Fetoproteins; Animals; Antineoplastic Agents, Phytogenic; Antioxidants; Ascorbic Acid; Camellia sinensis; Carcinoma, Hepatocellular; Catechin; Fibroblast Growth Factor 2; Gene Expression; Hep G2 Cells; Heparan Sulfate Proteoglycans; Humans; Liver; Liver Neoplasms; Male; Matrix Metalloproteinase 9; Neoplasm Invasiveness; Phytotherapy; Plant Extracts; Rats, Sprague-Dawley; Syndecan-1; Thioacetamide | 2014 |
Urinary biomarkers of catechins and risk of hepatocellular carcinoma in the Shanghai Cohort Study.
Topics: Biomarkers; Carcinoma, Hepatocellular; Case-Control Studies; Catechin; China; Cohort Studies; Hepatitis B Surface Antigens; Humans; Liver Neoplasms; Male; Middle Aged; Tea; Vitamin A | 2015 |
Protective effect of theaflavin-enriched black tea extracts against dimethylnitrosamine-induced liver fibrosis in rats.
Topics: Animals; Anticarcinogenic Agents; Biflavonoids; Bile Ducts, Intrahepatic; Biomarkers; Camellia sinensis; Carcinogens; Carcinoma, Hepatocellular; Catechin; Chemical and Drug Induced Liver Injury; Dietary Supplements; Dimethylnitrosamine; Food Handling; Liver; Liver Cirrhosis, Experimental; Liver Neoplasms; Male; Oxidation-Reduction; Plant Extracts; Plant Leaves; Protective Agents; Random Allocation; Rats, Sprague-Dawley | 2015 |
Epigallocatechin-3-gallate opposes HBV-induced incomplete autophagy by enhancing lysosomal acidification, which is unfavorable for HBV replication.
Topics: Antiviral Agents; Autophagy; Autophagy-Related Protein 5; Autophagy-Related Protein 7; Carcinoma, Hepatocellular; Catechin; Cell Line, Tumor; DNA Replication; DNA, Viral; Hep G2 Cells; Hepatitis B virus; Humans; Liver Neoplasms; Lysosomes; Microtubule-Associated Proteins; Plant Extracts; RNA Interference; RNA, Small Interfering; Tea; Ubiquitin-Activating Enzymes; Viral Core Proteins; Virus Replication | 2015 |
Preventive effects of a major component of green tea, epigallocathechin-3-gallate, on hepatitis-B virus DNA replication.
Topics: Antioxidants; Camellia sinensis; Carcinoma, Hepatocellular; Catechin; Cell Line, Tumor; DNA Replication; DNA, Viral; Hepatitis B e Antigens; Hepatitis B Surface Antigens; Hepatitis B virus; Humans; Liver Neoplasms; Tea; Virus Replication | 2015 |
Targeting increased copper levels in diethylnitrosamine induced hepatocellular carcinoma cells in rats by epigallocatechin-3-gallate.
Topics: Animals; Carcinoma, Hepatocellular; Catechin; Cell Membrane Permeability; Copper; Diethylnitrosamine; DNA Damage; Free Radical Scavengers; Humans; Liver Neoplasms; Oxidative Stress; Rats; Reactive Oxygen Species; Tea | 2015 |
Green tea component epigallocatechin-3-gallate decreases expression of osteopontin via a decrease in mRNA half-life in cell lines of metastatic hepatocellular carcinoma.
Topics: Antineoplastic Agents; Biomarkers, Tumor; Carcinoma, Hepatocellular; Catechin; Cell Line, Tumor; Cell Movement; Enzyme-Linked Immunosorbent Assay; Half-Life; Humans; Liver Neoplasms; Neoplasm Metastasis; Osteopontin; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2015 |
Epigallocatechin gallate hinders human hepatoma and colon cancer sphere formation.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Carcinoma, Hepatocellular; Catechin; Cell Cycle; Cell Proliferation; Colonic Neoplasms; Dose-Response Relationship, Drug; HCT116 Cells; Hep G2 Cells; Humans; Liver Neoplasms; Neoplastic Stem Cells; Tea | 2016 |
Folate deficiency-triggered redox pathways confer drug resistance in hepatocellular carcinoma.
Topics: Antineoplastic Agents; Apoptosis; Blotting, Western; Carcinoma, Hepatocellular; Catechin; Cell Line, Tumor; Cell Survival; Culture Media; Dose-Response Relationship, Drug; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Endoplasmic Reticulum Chaperone BiP; Folic Acid; Heat-Shock Proteins; Hep G2 Cells; Humans; Inhibitor of Apoptosis Proteins; Liver Neoplasms; Oxidation-Reduction; Reactive Oxygen Species; RNA Interference; Signal Transduction; Survivin | 2015 |
Tea polyphenols EGCG and TF restrict tongue and liver carcinogenesis simultaneously induced by N-nitrosodiethylamine in mice.
Topics: Animals; Apoptosis; beta Catenin; Biflavonoids; Body Weight; Carcinogenesis; Catechin; Cell Proliferation; Diethylnitrosamine; Female; Hedgehog Proteins; Liver Neoplasms; Mice; Polyphenols; Tongue Neoplasms; Up-Regulation; Wnt Proteins | 2016 |
In vitro and in vivo study of epigallocatechin-3-gallate-induced apoptosis in aerobic glycolytic hepatocellular carcinoma cells involving inhibition of phosphofructokinase activity.
Topics: Aerobiosis; Apoptosis; Carcinoma, Hepatocellular; Catechin; Glycolysis; Hep G2 Cells; Humans; Liver Neoplasms; Neoplasm Proteins; Phosphofructokinases | 2016 |
[Impact of epigallocatechin gallate on gene expression profiles of human hepatocellular carcinoma cell lines BEL7404/ADM and BEL7402/5-FU].
Topics: Anticarcinogenic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Carcinoma, Hepatocellular; Catechin; Cell Line, Tumor; Cyclin G1; Doxorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Fluorouracil; Gene Expression Profiling; Humans; Liver Neoplasms; Oligonucleotide Array Sequence Analysis; Vault Ribonucleoprotein Particles | 2008 |
[Epigallocatechin-3-gallate induces apoptosis in human hepatocellular carcinoma cells].
Topics: Apoptosis; bcl-X Protein; Carcinoma, Hepatocellular; Caspase 3; Caspase 9; Catechin; Cell Line, Tumor; Cyclooxygenase 2; Humans; Liver Neoplasms; Reverse Transcriptase Polymerase Chain Reaction | 2008 |
Epigallocatechin gallate up-regulation of miR-16 and induction of apoptosis in human cancer cells.
Topics: Anticarcinogenic Agents; Apoptosis; Carcinoma, Hepatocellular; Catechin; DNA Fragmentation; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Genes, bcl-2; Genes, Reporter; Hep G2 Cells; Humans; Liver Neoplasms; MicroRNAs; Oligonucleotide Array Sequence Analysis; Polymerase Chain Reaction; Proto-Oncogene Proteins c-bcl-2; Tea; Up-Regulation | 2010 |
Green tea polyphenol epigallocatechin-3-gallate inhibits thrombin-induced hepatocellular carcinoma cell invasion and p42/p44-MAPKinase activation.
Topics: Anticarcinogenic Agents; Carcinoma, Hepatocellular; Catechin; Cell Growth Processes; Cell Line, Tumor; Enzyme Activation; Humans; Liver Neoplasms; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Neoplasm Invasiveness; Oligopeptides; Phosphorylation; Receptor, PAR-1; Receptors, Thrombin; Tea; Thrombin | 2009 |
Catechin-induced activation of the LKB1/AMP-activated protein kinase pathway.
Topics: 3T3-L1 Cells; AMP-Activated Protein Kinase Kinases; AMP-Activated Protein Kinases; Animals; Antineoplastic Agents; Catechin; Cell Differentiation; Enzyme Activation; Humans; Liver; Liver Neoplasms; Liver Neoplasms, Experimental; Male; Mice; Mice, Inbred BALB C; Protein Kinases; Protein Serine-Threonine Kinases; Rats; Signal Transduction | 2009 |
(-)-Epigallocatechin gallate suppresses the growth of human hepatocellular carcinoma cells by inhibiting activation of the vascular endothelial growth factor-vascular endothelial growth factor receptor axis.
Topics: Animals; Anticarcinogenic Agents; bcl-X Protein; Blotting, Western; Carcinoma, Hepatocellular; Catechin; Cell Line, Tumor; Cell Proliferation; Extracellular Signal-Regulated MAP Kinases; Humans; Liver Neoplasms; Male; Mice; Mice, Nude; Proto-Oncogene Proteins c-akt; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor Receptor-2; Xenograft Model Antitumor Assays | 2009 |
(-)-Epigallocatechin-3-gallate induces apoptosis of human hepatoma cells by mitochondrial pathways related to reactive oxygen species.
Topics: Apoptosis; Catechin; Cell Line, Tumor; Cytochromes c; Humans; Liver Neoplasms; Membrane Potential, Mitochondrial; Mitochondria; Reactive Oxygen Species | 2009 |
Induction of apoptosis by immature plum in human hepatocellular carcinoma.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Carcinoma; Carrier Proteins; Caspases; Catechin; Cell Line, Tumor; Death Domain Receptor Signaling Adaptor Proteins; DNA Fragmentation; Fruit; Humans; Liver Neoplasms; Microfilament Proteins; Plant Extracts; Poly(ADP-ribose) Polymerases; Prunus; Signal Transduction | 2009 |
Myricetin, quercetin, (+)-catechin and (-)-epicatechin protect against N-nitrosamines-induced DNA damage in human hepatoma cells.
Topics: Antioxidants; Carcinogens; Carcinoma, Hepatocellular; Catechin; Cell Line, Tumor; Comet Assay; Cytoprotection; DNA Damage; Flavonoids; Humans; Liver Neoplasms; Mutagens; Nitrosamines; Quercetin | 2009 |
EGCG inhibits protein synthesis, lipogenesis, and cell cycle progression through activation of AMPK in p53 positive and negative human hepatoma cells.
Topics: Acetyl-CoA Carboxylase; AMP-Activated Protein Kinases; Anticarcinogenic Agents; Carcinoma, Hepatocellular; Catechin; Cell Cycle; Cell Line, Tumor; Fatty Acid Synthases; Humans; Lipogenesis; Liver Neoplasms; Protein Biosynthesis; Protein Kinases; TOR Serine-Threonine Kinases; Tumor Suppressor Protein p53 | 2009 |
Dietary flavonoids activate the constitutive androstane receptor (CAR).
Topics: Androstanes; Animals; Aryl Hydrocarbon Hydroxylases; Carcinoma, Hepatocellular; Catechin; Cell Line, Tumor; Constitutive Androstane Receptor; Cytochrome P450 Family 2; Diet; Flavonoids; Genes, Reporter; Humans; Liver; Liver Neoplasms; Luciferases; Mice; Mice, Knockout; Polymerase Chain Reaction; Receptors, Cytoplasmic and Nuclear; RNA, Messenger; Steroid Hydroxylases | 2010 |
[Effects of differentially expressed proteins in hepatocellular carcinoma cell treated by different telomerase inhibitors].
Topics: Carcinoma, Hepatocellular; Catechin; Cell Line, Tumor; Enzyme Inhibitors; Humans; Liver Neoplasms; Protein Array Analysis; Proteome; Telomerase; Tretinoin; Zidovudine | 2010 |
Dietary catechins and procyanidins modulate zinc homeostasis in human HepG2 cells.
Topics: Biflavonoids; Carcinoma, Hepatocellular; Catechin; Cation Transport Proteins; Diet; Gene Expression Regulation; Grape Seed Extract; Hep G2 Cells; Homeostasis; Humans; Interleukin-6; Liver Neoplasms; Metallothionein; Proanthocyanidins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Tea; Zinc | 2011 |
Carbonyl reductase 1 as a novel target of (-)-epigallocatechin gallate against hepatocellular carcinoma.
Topics: Alcohol Oxidoreductases; Animals; Antibiotics, Antineoplastic; Anticarcinogenic Agents; Carcinoma, Hepatocellular; Catechin; Daunorubicin; Humans; Liver Neoplasms; Mice; Tumor Cells, Cultured | 2010 |
Identification of components of grape powder with anti-apoptotic effects.
Topics: Anthocyanins; Apoptosis; Carcinoma, Hepatocellular; Caspase 3; Caspase 7; Catechin; Cell Death; Cell Line, Tumor; Cell Survival; Endoplasmic Reticulum; Food, Preserved; Freeze Drying; Fruit; Humans; Liver Neoplasms; Mitochondria, Liver; Oxidative Stress; Quercetin; Reactive Oxygen Species; Resveratrol; Stilbenes; Taurodeoxycholic Acid; Vitis | 2011 |
Lovastatin interacts with natural products to influence cultured hepatocarcinoma cell (hep-g2) growth.
Topics: Antineoplastic Agents; Capsaicin; Carcinoma, Hepatocellular; Catechin; Cell Line, Tumor; Cells, Cultured; Curcumin; Drug Synergism; Hep G2 Cells; Herb-Drug Interactions; Humans; Liver Neoplasms; Lovastatin; Plant Extracts | 2010 |
The anticancer flavonoid chrysin induces the unfolded protein response in hepatoma cells.
Topics: Antineoplastic Agents; Apoptosis; Carcinoma, Hepatocellular; Caspase 7; Catechin; Cell Line, Tumor; Cell Proliferation; DNA-Binding Proteins; Endoplasmic Reticulum Chaperone BiP; Endoplasmic Reticulum Stress; Eukaryotic Initiation Factor-2; Flavonoids; Heat-Shock Proteins; Hep G2 Cells; Humans; Liver Neoplasms; Phosphorylation; Poly(ADP-ribose) Polymerases; Proteasome Inhibitors; Regulatory Factor X Transcription Factors; RNA Interference; Transcription Factors; Unfolded Protein Response | 2011 |
Protective effect of quercetin, EGCG, catechin and betaine against oxidative stress induced by ethanol in vitro.
Topics: Aldehydes; Anti-Infective Agents, Local; Antioxidants; Betaine; Blotting, Western; Carcinoma, Hepatocellular; Catechin; Cells, Cultured; Cytochrome P-450 CYP2E1; Ethanol; Gastrointestinal Agents; Hepatocytes; Humans; In Vitro Techniques; Liver Neoplasms; Malondialdehyde; Oxidative Stress; Quercetin; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2011 |
Preventive effects of (-)-epigallocatechin gallate on diethylnitrosamine-induced liver tumorigenesis in obese and diabetic C57BL/KsJ-db/db Mice.
Topics: Adenoma; Animals; Anticarcinogenic Agents; Carcinogens; Catechin; Diabetes Mellitus, Experimental; Diethylnitrosamine; Extracellular Signal-Regulated MAP Kinases; Fatty Acids, Nonesterified; Liver; Liver Neoplasms; Male; Mice; Mice, Inbred C57BL; Obesity; Proto-Oncogene Proteins c-akt; Receptor, IGF Type 1 | 2011 |
Epigallocatechin-3-gallate induced modulation of cell deadhesion and migration on thermosensitive poly(N-isopropylacrylamide).
Topics: Acrylamides; Acrylic Resins; Anticarcinogenic Agents; Biocompatible Materials; Catechin; Cell Adhesion; Cell Movement; Hep G2 Cells; Humans; Liver Neoplasms; Polymers; Tea; Temperature | 2011 |
(-)-Epigallocatechin-3-gallate enhances the expression of an insulin-inducible transcription factor gene via a phosphoinositide 3-kinase/atypical protein kinase C lambda pathway.
Topics: Animals; Basic Helix-Loop-Helix Transcription Factors; Catechin; Cell Line, Tumor; Enzyme Inhibitors; Gene Expression; Insulin; Isoenzymes; Liver Neoplasms; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Protein Kinase C; Rats; RNA, Messenger; Signal Transduction | 2011 |
Prostanoid EP1 receptor as the target of (-)-epigallocatechin-3-gallate in suppressing hepatocellular carcinoma cells in vitro.
Topics: Alprostadil; Antineoplastic Agents, Phytogenic; Blotting, Western; Bridged Bicyclo Compounds; Caproates; Carcinoma, Hepatocellular; Catechin; Cell Movement; Cell Proliferation; Cell Survival; Dinoprostone; Dose-Response Relationship, Drug; GTP-Binding Protein alpha Subunits, Gq-G11; Hep G2 Cells; Humans; Immunoassay; Liver Neoplasms; Neoplasm Invasiveness; Receptors, Prostaglandin E, EP1 Subtype; Time Factors | 2012 |
Growth inhibition of Walker carcinosarcoma 256 with alcoholic extract of green tea leaves (Camellia sinensis).
Topics: Animals; Camellia sinensis; Carcinoma 256, Walker; Catechin; Kidney Neoplasms; Liver Neoplasms; Male; Phytotherapy; Plant Extracts; Rats; Rats, Wistar; Splenic Neoplasms; Tea | 2012 |
Sensitization of TRAIL-induced apoptosis in human hepatocellular carcinoma HepG2 cells by phytochemicals.
Topics: Apoptosis; Carcinoma, Hepatocellular; CASP8 and FADD-Like Apoptosis Regulating Protein; Caspase 3; Catechin; DNA Fragmentation; Dose-Response Relationship, Drug; Hep G2 Cells; Humans; Indoles; Inhibitory Concentration 50; Liver Neoplasms; Proto-Oncogene Proteins c-bcl-2; Receptors, TNF-Related Apoptosis-Inducing Ligand; TNF-Related Apoptosis-Inducing Ligand | 2013 |
Effect of tea catechins on cellular lipid peroxidation and cytotoxicity in HepG2 cells.
Topics: Antineoplastic Agents, Phytogenic; Catechin; Dose-Response Relationship, Drug; Enzyme Activation; Glutathione; Glutathione Disulfide; Glutathione Peroxidase; Humans; Lipid Peroxidation; Liver Neoplasms; Tea; tert-Butylhydroperoxide; Thiobarbituric Acid Reactive Substances; Tumor Cells, Cultured; Vitamin E | 2002 |
Genotoxic and antigenotoxic effects of catechin and tannins from the bark of Hamamelis virginiana L. in metabolically competent, human hepatoma cells (Hep G2) using single cell gel electrophoresis.
Topics: Anthocyanins; Antineoplastic Agents, Phytogenic; Benzo(a)pyrene; Carcinoma, Hepatocellular; Catechin; Cytochrome P-450 CYP1A1; DNA Damage; Electrophoresis, Agar Gel; Gallic Acid; Hamamelis; Hexoses; Humans; Liver Neoplasms; Mutagens; Plant Bark; Proanthocyanidins; Tumor Cells, Cultured | 2003 |
Green tea polyphenol epigallocatechin-3-gallate inhibits platelet-derived growth factor-induced proliferation of human hepatic stellate cell line LI90.
Topics: Antineoplastic Agents, Phytogenic; Becaplermin; Catechin; Cell Division; Cell Line, Tumor; Collagen Type I; Collagen Type IV; Humans; Liver; Liver Neoplasms; Phosphorylation; Platelet-Derived Growth Factor; Proto-Oncogene Proteins c-sis; Radioligand Assay; Receptors, Platelet-Derived Growth Factor; RNA, Messenger; Tea | 2004 |
Inhibition of liver cancer cell proliferation and migration by a combination of (-)-epigallocatechin-3-gallate and ascorbic acid.
Topics: Antioxidants; Ascorbic Acid; Catechin; Cell Division; Cell Movement; Colony Count, Microbial; Culture Media; Drug Therapy, Combination; Humans; Liver Neoplasms; Reference Values; Sensitivity and Specificity; Tumor Cells, Cultured | 2003 |
[MDR-reversing effect of two components of catechin on human hepatocellular carcinoma BEL-7404/Adr in vitro].
Topics: Carcinoma, Hepatocellular; Catechin; Cell Line, Tumor; Doxorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Humans; Liver Neoplasms | 2004 |
The theaflavin monomers inhibit the cancer cells growth in vitro.
Topics: Antineoplastic Agents; Biflavonoids; Catechin; Cell Division; Cell Line, Tumor; Chromatography, High Pressure Liquid; Humans; Leukemia, Promyelocytic, Acute; Liver Neoplasms; Stomach Neoplasms | 2004 |
Comparative effects of food-derived polyphenols on the viability and apoptosis of a human hepatoma cell line (HepG2).
Topics: Apoptosis; Carcinoma, Hepatocellular; Catechin; Cell Cycle; Cell Survival; Chlorogenic Acid; Flavonoids; Fragaria; Fruit; Humans; Liver Neoplasms; Phenols; Plant Extracts; Polyphenols; Prunus; Quercetin; Tumor Cells, Cultured | 2005 |
Effects of Pinus massoniana bark extract on cell proliferation and apoptosis of human hepatoma BEL-7402 cells.
Topics: Apoptosis; Biflavonoids; Carcinoma, Hepatocellular; Catechin; Cell Division; Cell Line, Tumor; Humans; Liver Neoplasms; Pinus; Plant Bark; Plant Extracts; Proanthocyanidins | 2005 |
Epigallocatechin gallate reduces hypoxia-induced apoptosis in human hepatoma cells.
Topics: Antigens, Neoplasm; Apoptosis; bcl-2-Associated X Protein; Blotting, Western; Cadherins; Carcinoma, Hepatocellular; Catechin; Cell Adhesion Molecules; Cell Hypoxia; Cell Line, Tumor; Coloring Agents; Epithelial Cell Adhesion Molecule; Genes, bcl-2; Humans; Immunohistochemistry; In Situ Nick-End Labeling; Liver Neoplasms; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2006 |
A green tea polyphenol, epigalocatechin-3-gallate, induces apoptosis of human hepatocellular carcinoma, possibly through inhibition of Bcl-2 family proteins.
Topics: Administration, Oral; Animals; Anticarcinogenic Agents; Apoptosis; Apoptosis Regulatory Proteins; bcl-2-Associated X Protein; bcl-X Protein; Camellia sinensis; Carcinoma, Hepatocellular; Caspases; Catechin; Cell Line, Tumor; Down-Regulation; Enzyme Activation; Humans; Liver Neoplasms; Male; Membrane Glycoproteins; Mice; Mice, Inbred Strains; RNA, Messenger; Tea; TNF-Related Apoptosis-Inducing Ligand; Tumor Necrosis Factor-alpha; Xenograft Model Antitumor Assays | 2006 |
Green tea extract and (-)-epigallocatechin-3-gallate inhibit hypoxia- and serum-induced HIF-1alpha protein accumulation and VEGF expression in human cervical carcinoma and hepatoma cells.
Topics: Angiogenesis Inhibitors; Anticarcinogenic Agents; Carcinoma; Carcinoma, Hepatocellular; Catechin; Cell Hypoxia; Culture Media; Extracellular Signal-Regulated MAP Kinases; Female; HeLa Cells; Humans; Hypoxia-Inducible Factor 1; Liver Neoplasms; Phosphatidylinositol 3-Kinases; Plant Extracts; RNA, Messenger; Sirolimus; Uterine Cervical Neoplasms; Vascular Endothelial Growth Factor A | 2006 |
Evidence of a novel antiapoptotic factor: role of inhibitor of differentiation or DNA binding (Id-1) in anticancer drug-induced apoptosis.
Topics: Antineoplastic Agents; Apoptosis; Breast Neoplasms; Carcinoma, Hepatocellular; Catechin; Cell Line, Tumor; Cell Survival; Cisplatin; Down-Regulation; Doxorubicin; Etoposide; Female; HeLa Cells; Humans; Inhibitor of Differentiation Protein 1; Liver Neoplasms; Male; Mechlorethamine; Methotrexate; Mitomycin; Nasopharyngeal Neoplasms; Paclitaxel; Prostatic Neoplasms; Vincristine | 2007 |
Structure-activity relationships of tea compounds against human cancer cells.
Topics: Anticarcinogenic Agents; Biflavonoids; Breast Neoplasms; Camellia sinensis; Catechin; Cell Death; Cell Line, Tumor; Glutamates; HT29 Cells; Humans; Liver Neoplasms; Male; Plant Leaves; Prostatic Neoplasms; Stomach Neoplasms; Structure-Activity Relationship; Tea | 2007 |
Molecular mechanisms of (-)-epicatechin and chlorogenic acid on the regulation of the apoptotic and survival/proliferation pathways in a human hepatoma cell line.
Topics: Apoptosis; Carcinoma, Hepatocellular; Catechin; Cell Division; Cell Line, Tumor; Cell Survival; Chlorogenic Acid; Extracellular Signal-Regulated MAP Kinases; Humans; Liver Neoplasms; Phosphatidylinositol 3-Kinases; Phosphorylation; Proto-Oncogene Proteins c-akt; Reactive Oxygen Species | 2007 |
EGCG inhibits activation of the insulin-like growth factor (IGF)/IGF-1 receptor axis in human hepatocellular carcinoma cells.
Topics: Carcinoma, Hepatocellular; Catechin; Cell Line, Tumor; Cell Proliferation; Hepatocytes; Humans; Liver Neoplasms; Phosphorylation; Receptor, IGF Type 1; Signal Transduction | 2008 |
Effect of green tea and (-)-epigallocatechin gallate on ethanol-induced toxicity in HepG2 cells.
Topics: Acetylcysteine; Carcinoma, Hepatocellular; Catechin; Cell Line, Tumor; Cell Survival; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Ethanol; gamma-Glutamyltransferase; Glutathione; Humans; Liver Neoplasms; Plant Extracts; Tea | 2008 |
[Effect of epigallocatechin-3-gallate on the invasiveness of hepatocarcinoma cells in vitro].
Topics: Carcinoma, Hepatocellular; Catechin; Cell Adhesion; Cell Survival; Hep G2 Cells; Humans; Liver Neoplasms; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Mucin-1; Neoplasm Invasiveness; Plant Extracts | 2007 |
Time-course regulation of survival pathways by epicatechin on HepG2 cells.
Topics: Carcinoma, Hepatocellular; Catechin; Cell Death; Cell Line, Tumor; Cell Survival; Humans; Kinetics; L-Lactate Dehydrogenase; Liver Neoplasms; Phosphatidylinositol 3-Kinases; Phosphorylation; Proto-Oncogene Proteins c-akt; Reactive Oxygen Species; Signal Transduction | 2009 |
Epigallocatechin gallate (EGCG) attenuates high glucose-induced insulin signaling blockade in human hepG2 hepatoma cells.
Topics: Adaptor Proteins, Signal Transducing; Adenylate Kinase; Carcinoma, Hepatocellular; Catechin; Cell Line, Tumor; Glucose; Humans; Insulin Receptor Substrate Proteins; Insulin Resistance; JNK Mitogen-Activated Protein Kinases; Liver Neoplasms; Phosphorylation; Protein Kinase C; Proto-Oncogene Proteins c-akt; Signal Transduction | 2008 |
Inhibitory effects of (-)-epigallocatechin gallate on spontaneous hepatoma in C3H/HeNCrj mice and human hepatoma-derived PLC/PRF/5 cells.
Topics: alpha-Fetoproteins; Animals; Anticarcinogenic Agents; Antineoplastic Agents; Carcinoma, Hepatocellular; Catechin; Cell Division; Humans; Liver Neoplasms; Liver Neoplasms, Experimental; Male; Mice; Mice, Inbred C3H; Mice, Inbred Strains; Tumor Cells, Cultured | 1994 |
Chemoprevention of heterocyclic amine-induced carcinogenesis by phenolic compounds in rats.
Topics: Animals; Antioxidants; Carcinogens; Catechin; Colonic Neoplasms; Drug Antagonism; Imidazoles; Liver Neoplasms; Male; Quinolines; Rats; Rats, Inbred F344; Tannins | 1999 |
Comparative studies on the effects of green tea extracts and individual tea catechins on human CYP1A gene expression.
Topics: Animals; Carcinoma, Hepatocellular; Catechin; Cytochrome P-450 CYP1A1; DNA; Gene Expression; Guinea Pigs; Humans; Liver; Liver Neoplasms; Male; Mice; Plant Extracts; Polychlorinated Dibenzodioxins; Receptors, Aryl Hydrocarbon; RNA, Messenger; Tea; Tumor Cells, Cultured | 2000 |
Inhibition of green tea catechins against the growth of cancerous human colon and hepatic epithelial cells.
Topics: Beverages; Catechin; Cell Division; Colonic Neoplasms; Epithelial Cells; Humans; Liver Neoplasms; Tumor Cells, Cultured | 2001 |
Chemopreventive effects of green tea components on hepatic carcinogenesis.
Topics: Animals; Beverages; Catechin; China; Free Radicals; Liver; Liver Neoplasms; Male; Mice; Tea | 1992 |
[Inhibition effect of epicatechin on phenobarbitol-induced proliferation precancerous liver cells].
Topics: Animals; Catechin; Diethylnitrosamine; Flavonoids; Liver Neoplasms; Male; Phenobarbital; Precancerous Conditions; Rats; Rats, Inbred Strains; Tea | 1990 |
Effect of (+)-catechin, dimethyl sulfoxide and ethanol on the microsome-mediated metabolism of two hepatocarcinogens, N-nitrosodimethylamine and aflatoxin B1.
Topics: Aflatoxin B1; Aflatoxins; Animals; Catechin; Cricetinae; Dimethyl Sulfoxide; Dimethylnitrosamine; DNA; Dose-Response Relationship, Drug; Ethanol; Liver Neoplasms; Microsomes, Liver | 1987 |