catechin and Liver Cirrhosis

catechin has been researched along with Liver Cirrhosis in 29 studies

Research

Studies (29)

TimeframeStudies, this research(%)All Research%
pre-19908 (27.59)18.7374
1990's0 (0.00)18.2507
2000's3 (10.34)29.6817
2010's15 (51.72)24.3611
2020's3 (10.34)2.80

Authors

AuthorsStudies
George, J; Tsuchishima, M; Tsutsumi, M1
Chen, J; Lei, Y; Liu, J; Liu, M1
Erstad, DJ; Fuchs, BC; Fujii, T; Hirschfield, H; Hoshida, Y; Kim, RS; Lanuti, M; Lauwers, GY; Sojoodi, M; Tanabe, KK; Wei, L; Yamada, S1
Gao, H; Hu, Y; Li, X; Tian, R; Wang, Y; Williams, BR; Xu, P; Yan, F; Ying, L; Zhao, Y1
Ho, CT; Li, S; Wang, L; Yang, G; Yang, Y; Yuan, L; Zhao, H1
Chen, J; Chen, K; Dai, W; Fan, X; Feng, J; Guo, C; Ji, J; Li, J; Li, S; Liu, T; Mao, Y; Wang, C; Wang, F; Wu, J; Wu, L; Yu, Q; Zhang, J; Zhou, Y1
Baba, A; Kochi, T; Kubota, M; Moriwaki, H; Ohno, T; Shimizu, M; Shirakami, Y; Tanaka, T; Terakura, D; Tsurumi, H1
He, M; Li, Y; Liao, M; Lin, X; Luo, Y; Zhang, X1
Cai, SY; He, HW; Shao, RG; Yu, DK; Zhang, CX; Zhang, H; Zhang, SH; Zhao, SS1
Feng, X; Shen, K; Su, R; Xie, H; Zheng, S; Zhou, L1
Du, N; Li, L; Wang, K; Wang, Z; Zhang, Z1
Cao, W; Li, M; Li, Y; Liao, M; Zhang, X1
Al-Gayyar, MM; Arffa, ML; Chang, V; Ding, X; Elsherbiny, NM; Gupta, GN; Kothari, AN; Kuo, PC; Mi, Z; Syn, W; Zapf, MA1
Adachi, S; Hara, Y; Iwasa, J; Kubota, M; Moriwaki, H; Osawa, Y; Sakai, H; Shimizu, M; Tsurumi, H; Yasuda, Y1
Asagiri, K; Asakawa, T; Kage, M; Kobayashi, H; Tanaka, Y; Tanikawa, K; Yagi, M1
Fung, ML; Lau, TY; Leung, TM; Liong, EC; Nanji, AA; Tipoe, GL1
Abraldes, JG; Berzigotti, A; Bosch, J; D'Amico, M; De Gottardi, A; García-Pagán, JC; Seijo, S; Thormann, W1
He, M; Huang, Q; Huang, R; Liao, M; Lin, X; Wei, L; Zhang, S; Zheng, L; Zhuo, L1
Daskalakis, C; Halegoua-De Marzio, D; Hawke, RL; Kraft, WK; Navarro, VJ; Ying, X1
Enjoji, M; Fukushima, M; Higashi, N; Kobayashi, N; Kohjima, M; Kotoh, K; Nakamuta, M; Ohta, S1
Cao, LQ; Chen, XL; Huang, XH; Li, W; Liu, YJ; Sun, K; Wang, Q; Zhang, LJ; Zhen, MC1
Göbel, J; Pausch, V1
Beck, P; Boda, Z; Dalmi, L; Misz, M; Pfliegler, G; Weisz, G1
Ikeda, Y; Ito, K; Nose, T; Sato, I; Tajima, S; Takebe, H1
Divald, A; Jeney, A; Lapis, K; Schaff, Z; Vajta, G; Zalatnai, A1
Cornides, A; Deák, G; Fehér, J; Gergely, P; Láng, I; Nékám, K1
Ausheva, LKh; Bendikov, EA; Blok, IuE; Dzhalalov, KD; Loginov, AS1
Kostova, N; Krŭstev, Z; Lukanov, L; Maleev, A; Tsvetkova, V1
Dement'eva, ES; Krylova, NI; Neverov, IV; Tamarkina, AD; Turitsyna, IG1

Trials

2 trial(s) available for catechin and Liver Cirrhosis

ArticleYear
Postprandial effects of dark chocolate on portal hypertension in patients with cirrhosis: results of a phase 2, double-blind, randomized controlled trial.
    The American journal of clinical nutrition, 2012, Volume: 96, Issue:3

    Topics: Adult; Aged; Antioxidants; Cacao; Catechin; Double-Blind Method; Female; Flavonoids; Food, Formulated; Humans; Hyperemia; Hypertension, Portal; Liver Circulation; Liver Cirrhosis; Male; Middle Aged; Nitric Oxide; Oxidative Stress; Pigmentation; Postprandial Period

2012
Limited sampling estimates of epigallocatechin gallate exposures in cirrhotic and noncirrhotic patients with hepatitis C after single oral doses of green tea extract.
    Clinical therapeutics, 2012, Volume: 34, Issue:12

    Topics: Administration, Oral; Aged; Antioxidants; Area Under Curve; Catechin; Female; Follow-Up Studies; Hepatitis C, Chronic; Humans; Liver Cirrhosis; Male; Middle Aged; Plant Extracts; Tea; Time Factors

2012

Other Studies

27 other study(ies) available for catechin and Liver Cirrhosis

ArticleYear
Epigallocatechin-3-gallate inhibits osteopontin expression and prevents experimentally induced hepatic fibrosis.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2022, Volume: 151

    Topics: Animals; Body Weight; Catechin; Collagen Type I; Collagen Type IV; Dimethylnitrosamine; Fibrosis; Hepatic Stellate Cells; Hyaluronic Acid; Liver; Liver Cirrhosis; Malondialdehyde; Osteopontin; Rats

2022
Potential ameliorative effects of epigallocatechin-3-gallate against cigarette smoke exposure induced renal and hepatic deficits.
    Ecotoxicology and environmental safety, 2020, Mar-15, Volume: 191

    Topics: Animals; Catechin; Epithelial-Mesenchymal Transition; Fibrosis; Inflammation; Kidney; Liver; Liver Cirrhosis; Male; Oxidative Stress; Rats; Tobacco Smoke Pollution; Transforming Growth Factor beta1

2020
Epigallocatechin Gallate Induces Hepatic Stellate Cell Senescence and Attenuates Development of Hepatocellular Carcinoma.
    Cancer prevention research (Philadelphia, Pa.), 2020, Volume: 13, Issue:6

    Topics: Animals; Anticarcinogenic Agents; Biomarkers; Carcinoma, Hepatocellular; Catechin; Cellular Senescence; Diethylnitrosamine; Hepatic Stellate Cells; Liver Cirrhosis; Liver Neoplasms, Experimental; Male; Phenotype; Precancerous Conditions; Rats; Tea; Transcriptome

2020
(-)-Epigallocatechin-3-gallate and atorvastatin treatment down-regulates liver fibrosis-related genes in non-alcoholic fatty liver disease.
    Clinical and experimental pharmacology & physiology, 2017, Volume: 44, Issue:12

    Topics: Animals; Atorvastatin; Catechin; Disease Models, Animal; Down-Regulation; Fibrillar Collagens; Gene Expression; Humans; Liver Cirrhosis; Male; Mice, Inbred C57BL; Multigene Family; Non-alcoholic Fatty Liver Disease

2017
Green Tea Catechins Effectively Altered Hepatic Fibrogenesis in Rats by Inhibiting ERK and Smad1/2 Phosphorylation.
    Journal of agricultural and food chemistry, 2019, May-15, Volume: 67, Issue:19

    Topics: Animals; Camellia sinensis; Catechin; Female; Humans; Liver; Liver Cirrhosis; MAP Kinase Signaling System; Phosphorylation; Plant Extracts; Rats; Rats, Sprague-Dawley; Smad1 Protein; Smad2 Protein; Transforming Growth Factor beta

2019
Procyanidin B2 inhibits the activation of hepatic stellate cells and angiogenesis via the Hedgehog pathway during liver fibrosis.
    Journal of cellular and molecular medicine, 2019, Volume: 23, Issue:9

    Topics: Animals; Biflavonoids; Carbon Tetrachloride; Catechin; Cell Line; Cell Proliferation; Down-Regulation; Hedgehog Proteins; Hepatic Stellate Cells; Humans; Liver; Liver Cirrhosis; Male; Mice; Mice, Inbred C57BL; Morphogenesis; Neovascularization, Pathologic; Proanthocyanidins; Signal Transduction; Transforming Growth Factor beta1; Veratrum Alkaloids

2019
Non-alcoholic steatohepatitis and preneoplastic lesions develop in the liver of obese and hypertensive rats: suppressing effects of EGCG on the development of liver lesions.
    Cancer letters, 2014, Jan-01, Volume: 342, Issue:1

    Topics: Angiotensin II; Animals; Anticarcinogenic Agents; Catechin; Fatty Liver; Gene Expression; Hypertension; Interleukin-6; Lipid Peroxidation; Liver; Liver Cirrhosis; Liver Neoplasms; Male; Non-alcoholic Fatty Liver Disease; Obesity; Oxidative Stress; Peptidyl-Dipeptidase A; Precancerous Conditions; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptor, Angiotensin, Type 1; Tumor Necrosis Factor-alpha

2014
Combined taurine, epigallocatechin gallate and genistein therapy reduces HSC-T6 cell proliferation and modulates the expression of fibrogenic factors.
    International journal of molecular sciences, 2013, Oct-14, Volume: 14, Issue:10

    Topics: Animals; Catechin; Cell Line; Cell Proliferation; Collagen Type I; Down-Regulation; Drug Therapy, Combination; Genistein; Liver Cirrhosis; Matrix Metalloproteinase 2; Rats; RNA, Messenger; Taurine; Tissue Inhibitor of Metalloproteinase-1; Tissue Inhibitor of Metalloproteinase-2; Transforming Growth Factor beta1; Up-Regulation

2013
The anti-fibrotic effects of epigallocatechin-3-gallate in bile duct-ligated cholestatic rats and human hepatic stellate LX-2 cells are mediated by the PI3K/Akt/Smad pathway.
    Acta pharmacologica Sinica, 2015, Volume: 36, Issue:4

    Topics: Animals; Bile Ducts; Catechin; Cell Line; Cholestasis; Hepatic Stellate Cells; Humans; Liver; Liver Cirrhosis; Male; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Signal Transduction; Smad Proteins

2015
Epigallocatechin 3-gallate ameliorates bile duct ligation induced liver injury in mice by modulation of mitochondrial oxidative stress and inflammation.
    PloS one, 2015, Volume: 10, Issue:5

    Topics: Animals; Bile Ducts, Intrahepatic; Catechin; Cell Death; Cholestasis; Cytokines; Disease Models, Animal; Gene Expression Regulation; Hepatic Stellate Cells; Hepatocytes; Inflammation; Liver Cirrhosis; Mice; Mitochondria; NF-kappa B; Oxidative Stress

2015
Hepatoprotective Effects of Grape Seed Procyanidin B2 in Rats With Carbon Tetrachloride-induced Hepatic Fibrosis.
    Alternative therapies in health and medicine, 2015, Volume: 21 Suppl 2

    Topics: Animals; Antioxidants; Biflavonoids; Carbon Tetrachloride; Catechin; Cytokines; Grape Seed Extract; Liver; Liver Cirrhosis; Male; Oxidative Stress; Proanthocyanidins; Rats; Rats, Sprague-Dawley; Seeds; Vitis

2015
Txn1, Ctsd and Cdk4 are key proteins of combination therapy with taurine, epigallocatechin gallate and genistein against liver fibrosis in rats.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2017, Volume: 85

    Topics: Animals; Anticarcinogenic Agents; Carbon Tetrachloride Poisoning; Catechin; Cathepsin D; Cyclin-Dependent Kinase 4; Drug Therapy, Combination; Genistein; Liver Cirrhosis; Male; Rats; Rats, Sprague-Dawley; Taurine; Thioredoxins; Transcriptome

2017
Epigallocatechin-3-Gallate Upregulates miR-221 to Inhibit Osteopontin-Dependent Hepatic Fibrosis.
    PloS one, 2016, Volume: 11, Issue:12

    Topics: Animals; Antioxidants; Catechin; Cell Line; Hep G2 Cells; Hepatic Stellate Cells; Humans; Liver Cirrhosis; Male; MicroRNAs; Osteopontin; Rats, Sprague-Dawley; Tea; Up-Regulation

2016
(-)-Epigallocatechin gallate prevents carbon tetrachloride-induced rat hepatic fibrosis by inhibiting the expression of the PDGFRbeta and IGF-1R.
    Chemico-biological interactions, 2009, Dec-10, Volume: 182, Issue:2-3

    Topics: Actins; Alanine Transaminase; Animals; Anticarcinogenic Agents; Aspartate Aminotransferases; Carbon Tetrachloride; Catechin; Gene Expression; Liver; Liver Cirrhosis; Male; Rats; Rats, Wistar; Receptor, IGF Type 1; Receptor, Platelet-Derived Growth Factor beta; RNA, Messenger

2009
The antioxidant effect of green tea catechin ameliorates experimental liver injury.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2010, Volume: 17, Issue:3-4

    Topics: Actins; Alanine Transaminase; Aldehydes; Animals; Antioxidants; Aspartate Aminotransferases; Camellia sinensis; Catechin; Cholestasis; Deoxyguanosine; Disease Models, Animal; Hepatic Stellate Cells; Liver; Liver Cirrhosis; Male; Oxidative Stress; Phytotherapy; Plant Extracts; Rats; Rats, Wistar; RNA, Messenger; Tissue Inhibitor of Metalloproteinase-1; Transcription Factor AP-1; Transforming Growth Factor beta1

2010
Epigallocatechin-3-gallate (EGCG) reduces liver inflammation, oxidative stress and fibrosis in carbon tetrachloride (CCl4)-induced liver injury in mice.
    Toxicology, 2010, Jun-29, Volume: 273, Issue:1-3

    Topics: Actins; Animals; Anti-Inflammatory Agents; Carbon Tetrachloride; Catechin; Chemical and Drug Induced Liver Injury; Collagen Type I; Cyclooxygenase 2 Inhibitors; Liver Cirrhosis; Male; Matrix Metalloproteinases; Mice; Mice, Inbred C57BL; Nitric Oxide Synthase Type II; Oxidative Stress; Tissue Inhibitor of Metalloproteinases; Transforming Growth Factor beta1; Tumor Necrosis Factor-alpha; Tyrosine

2010
Combination therapy with taurine, epigallocatechin gallate and genistein for protection against hepatic fibrosis induced by alcohol in rats.
    Biological & pharmaceutical bulletin, 2012, Volume: 35, Issue:10

    Topics: Actins; Alanine Transaminase; Alkaline Phosphatase; Animals; Antioxidants; Aspartate Aminotransferases; Catechin; Cytokines; Disease Models, Animal; Drug Therapy, Combination; Ethanol; gamma-Glutamyltransferase; Genistein; Liver Cirrhosis; Peroxidase; Proto-Oncogene Proteins c-bcl-2; Rats; RNA, Messenger; Smad3 Protein; Taurine

2012
Epigallocatechin-3-gallate, a green-tea polyphenol, suppresses Rho signaling in TWNT-4 human hepatic stellate cells.
    The Journal of laboratory and clinical medicine, 2005, Volume: 145, Issue:6

    Topics: Actins; Anticarcinogenic Agents; Apoptosis; Catechin; Cell Division; Cell Line; Flavonoids; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Hepatocytes; Humans; In Vitro Techniques; JNK Mitogen-Activated Protein Kinases; Liver Cirrhosis; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; p38 Mitogen-Activated Protein Kinases; Phenols; Phosphorylation; Polyphenols; Protein-Tyrosine Kinases; rho GTP-Binding Proteins; Stress Fibers; Tea

2005
Green tea polyphenol epigallocatechin-3-gallate inhibits oxidative damage and preventive effects on carbon tetrachloride-induced hepatic fibrosis.
    The Journal of nutritional biochemistry, 2007, Volume: 18, Issue:12

    Topics: Animals; Beverages; Carbon Tetrachloride Poisoning; Catechin; Cell Culture Techniques; Disease Models, Animal; Disease Progression; Enzyme Activation; Liver; Liver Cirrhosis; Male; Matrix Metalloproteinase 2; Rats; Rats, Sprague-Dawley; Rats, Wistar

2007
[Immunohematologic studies on the correlations between (+)-cyanidanol-3-(catergen) therapy and hemolytic anemia].
    Wiener medizinische Wochenschrift (1946), 1983, Nov-15, Volume: 133, Issue:21

    Topics: Anemia, Hemolytic, Autoimmune; Benzopyrans; Catechin; Erythrocytes; Hemagglutination Tests; Hepatitis C; Humans; Liver Cirrhosis; Penicillin G

1983
Effect of Catergen [(+)cyanidanol-3] on some haemostatic parameters in chronic liver diseases.
    Therapia Hungarica (English edition), 1984, Volume: 32, Issue:1

    Topics: Adult; Aged; Blood Coagulation Tests; Catechin; Clinical Enzyme Tests; Fatty Liver; Female; Hemostasis; Hepatitis, Chronic; Humans; Liver Cirrhosis; Liver Diseases; Male; Middle Aged; Time Factors

1984
[Effects of cianidanol (KB-53) on liver cirrhosis induced by CCl4 in rats: a pathological investigation].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1983, Volume: 81, Issue:6

    Topics: Animals; Benzopyrans; Carbon Tetrachloride Poisoning; Catechin; Flavonoids; Liver; Liver Cirrhosis; Male; Rats; Rats, Inbred Strains

1983
Experimental studies on the effect of hepatoprotective compounds.
    The Tokai journal of experimental and clinical medicine, 1986, Volume: 11 Suppl

    Topics: Aminoimidazole Carboxamide; Animals; Carbon Tetrachloride Poisoning; Catechin; Chemical and Drug Induced Liver Injury; Epoprostenol; Flavonoids; Galactosamine; Imidazoles; Liver; Liver Cirrhosis; Male; Mice; Mice, Inbred C57BL; Rats; Rats, Inbred F344; Ribonucleosides; Silymarin

1986
Free radicals in tissue damage in liver diseases and therapeutic approach.
    The Tokai journal of experimental and clinical medicine, 1986, Volume: 11 Suppl

    Topics: Aminoimidazole Carboxamide; Antioxidants; Catechin; Flavonoids; Free Radicals; Humans; Imidazoles; Immunosuppressive Agents; Liver; Liver Cirrhosis; Lymphocyte Activation; Quinolines; Ribonucleosides; Silymarin; Superoxide Dismutase; Thiazoles

1986
[Treatment of chronic diseases of the liver with catergen].
    Terapevticheskii arkhiv, 1986, Volume: 58, Issue:2

    Topics: Adolescent; Adult; Aged; Benzopyrans; Catechin; Chronic Disease; Fatty Liver, Alcoholic; Female; Hepatitis, Chronic; Humans; Lipid Peroxides; Liver Cirrhosis; Liver Cirrhosis, Alcoholic; Liver Cirrhosis, Biliary; Liver Diseases; Male; Middle Aged; Phosphatidylcholines

1986
[Clinical study of the effect of the administration of cathergen preparation in patients with chronic hepatic lesions].
    Vutreshni bolesti, 1985, Volume: 24, Issue:5

    Topics: Adult; Aged; Benzopyrans; Catechin; Chronic Disease; Fatty Liver; Female; Hepatitis; Hepatitis, Chronic; Humans; Liver Cirrhosis; Liver Diseases; Male; Middle Aged

1985
[Enzymologic evaluation of the effectiveness of the hepatotropic drug catergen in chronic liver diseases].
    Sovetskaia meditsina, 1985, Issue:12

    Topics: Adult; Aged; Antioxidants; Benzopyrans; Catechin; Chronic Disease; Hepatitis; Humans; Liver; Liver Cirrhosis; Middle Aged

1985