Compounds > catechin

catechin and Disease Models, Animal

catechin has been researched along with Disease Models, Animal in 463 studies

Research

Studies (463)

TimeframeStudies, this research(%)All Research%
pre-19901 (0.22)18.7374
1990's8 (1.73)18.2507
2000's79 (17.06)29.6817
2010's292 (63.07)24.3611
2020's83 (17.93)2.80

Authors

AuthorsStudies
Cuendet, M; Fong, HH; Hawthorne, ME; Kardono, LB; Kinghorn, AD; Mehta, RG; Pezzuto, JM; Riswan, S; Su, BN1
Braisted, J; Dranchak, P; Earnest, TW; Gu, X; Hoon, MA; Inglese, J; Oliphant, E; Solinski, HJ1
Abrams, RPM; Bachani, M; Balasubramanian, A; Brimacombe, K; Dorjsuren, D; Eastman, RT; Hall, MD; Jadhav, A; Lee, MH; Li, W; Malik, N; Nath, A; Padmanabhan, R; Simeonov, A; Steiner, JP; Teramoto, T; Yasgar, A; Zakharov, AV1
Guo, N; Hao, K; Liu, C; Liu, Z1
Hirai, C; Kan, T; Kurokawa, A; Masuda, S; Noaki, R; Shimamura, Y; Utsumi, M1
Cui, Y; Liu, G; Wang, Y1
Jang, S; Kim, HJ; Kim, T; Park, SH; Song, HK1
Chen, JX; He, YL; Lin, WT; Wei, X; Xu, WX; Zeng, M1
Ceballos, G; Cedeño-Garcidueñas, AL; Espinosa-Raya, J; Garate-Carrillo, A; Gomez-Diaz, B; Lara-Hernandez, M; Moreno-Ulloa, A; Navarrete-Yañez, V; Ramirez-Sanchez, I; Villarreal, F1
Han, X; Huang, L; Luo, X; Mao, Q; Peng, C; Wu, S; Zhang, H1
Jang, M; Jung, W; Park, J; Park, R; Park, Y; Park, YI1
Liu, L; Luo, M; Mou, Q; Tian, J1
Chen, Q; Huang, L; Jiao, W; Liu, S; Liu, W; Zhang, C; Zhang, Y; Zhao, T; Zhong, S1
Chen, S; He, P; Li, B; Tu, Y; Wang, K; Wu, J; Zhao, H1
Huang, X; Jia, Z; Liu, L; Luo, M; Mou, Q; Quan, J; Tian, J1
Cao, Y; Liu, S; Ma, L; Ma, Y; Ramos-Mucci, L; Sun, J; Xiao, B; Yang, X; Zhang, J; Zhu, Z1
Chang, HW; Chen, LC; Cheng, TC; Fang, CL; Ho, YS; Kuo, CC; Lee, WJ; Liao, YC; Lin, LC; Tu, SH; Yen, Y1
Abdel-Moneim, AM; Abdelmeguid, NE; Hammad, TM; Salam, SA1
Akhtar, MF; Bukhari, SA; Mubeen, A; Najda, A; Saleem, A; Zeb, A1
Cremonini, E; Kang, J; Le Gall, G; Muller, M; Oteiza, PI; Pontifex, MG; Vauzour, D; Wang, Z1
Chen, SM; Li, WJ; Luo, YP; Tang, XF; Wu, Q; Zhang, YC1
Callaerts-Vegh, Z; González-Colom, R; Llambrich, S; Martínez-Abadías, N; Roldán, J; Salassa, S; Sharpe, J; Van Bulck, V; Vande Velde, G; Wouters, J; Wouters, K1
Bae, KH; Chan, KH; Chen, Q; Her, Z; Kurisawa, M; Lai, F; Mong, J; Niibori-Nambu, A; Osato, M; Tan, MH1
Chen, H; Guo, J; Jin, S; Qin, T; Yao, D1
Chen, L; Gan, X; Jian, J; Liang, R; Wang, R; Yu, Q; Zhang, N1
Chakkittukandiyil, A; Kothandan, R; Rymbai, E; Selvaraj, D; Selvaraj, J; Sugumar, D1
Ding, Q; Fang, R; Qin, P; Wang, X; Wu, H; Xu, F; Yu, P; Zhang, M1
Chen, MH; Fang, W; Li, N; Qin, S; Qin, T; Tan, XF; Xie, L; Yang, YG1
Gao, B; Guo, ZW; Li, YQ; Lu, MD; Wang, ZY; Xue, TC; Zhou, XH1
Chen, X; He, K; Huang, X; Liu, J; Nie, L; Spencer, P; Xu, B; Yang, X; Zhou, L1
Hochstetter, D; Mao, L; Wang, Y; Xu, P; Yao, L; Zhao, Y; Zhou, J1
Dagli, AF; Gencoglu, H; Karatas, A; Koca, SS; Orhan, C; Ozgen, M; Sahin, K; Sahin, N1
Dong, R; Wang, J; Wang, X; Wu, X; Yang, CS; Yang, L; Zhang, J; Zhang, Y; Zhang, Z1
Chen, L; Gan, X; Jian, J; Liang, R; Yang, X; Zhang, C1
Chang, KC; Fang, CH; Li, KY; Lin, YW; Soung, HS; Tsai, CC; Tseng, HC; Wang, MH; Yang, CC1
Aral, M; Ergün, Y; Hedef, A; Kaya, E; Kılınç, M1
Bang, IJ; Chung, KH; Jeong, MH; Kim, DM; Kim, HR; Kim, KH; Kwon, SH; Park, YJ; So, HM; Yu, JS1
Gao, Q; Granato, D; Hu, L; Kan, Z; Li, X; Peng, CY; Qian, F; Wang, D; Wang, T; Wang, Y1
Ceballos, G; Hidalgo, I; Meaney, E; Nájera, N; Pérez-Durán, J; Valdespino-Vazquez, Y; Villarreal, F1
Gao, H; Li, M; Wu, Y; Xiao, Y; Zhong, K1
Dhir, A1
Cui, J; Wu, Y1
Hu, Y; Hu, Z; Huang, S; Liu, H; Shang, P; Tang, Q; Zhu, J1
Chang, WL; Clapper, ML; Cooper, HS1
Li, Y; Wang, HL; Xiang, L; Xiao, G; Xiao, J; Xie, M; Xu, Y; Xue, J1
Bao, J; Gui, YR; Liu, W; Long, GF; Shang, JT; Shu, XJ; Wu, MJ; Xiao, YF; Yang, YH; Zhou, HY1
Chen, X; Ji, X; Li, J; Liu, S; Luo, D; Ma, X; Xu, J; Xu, X; Zhao, J; Zhu, X1
Kang, JB; Koh, PO; Park, DJ2
Abd Eldaim, MA; Abdallah, AEM; Abdel-Daim, MM; Abdelaziz, SAM; Abdul Rashid, S; Abdullah, AS; Abdullah, LC; Abramson, MJ; Ahmed, HB; Ahmed, MM; Ahn, YC; Alexander, DC; Ando, T; Angelone, AM; Anglani, F; Ap, Y; Arthanari, SK; Axelrad, C; Bai, S; Bakonyi, P; Barnes, E; Beckmann, NA; Bélafi-Bakó, K; Bennett, CM; Bestha, RM; Bitsch, RG; Bradley, CA; Bu, Y; Calò, LA; Cañedo-Villaroya, E; Carlson, L; Caruso, S; Casado-Flores, J; Ceol, M; Cesarino, I; Chen, IL; Chen, R; Chen, X; Chilvers, MI; Cho, WK; Choong, TSY; Conceição-Neto, N; Culver, EL; Dai, X; de Lama Caro-Patón, G; De Rosa, I; Del Prete, D; Dharmage, SC; Dimitriadis, E; Dittakavi, S; Dobrowolski, JC; Edin, S; Elgarawany, GE; Emam, HE; Emmens, RW; Erbas, B; Erwich, JJHM; Farghali, M; Feng, L; Funston, RN; Gabler, NK; Gale, P; Ganesh, M; Gao, J; Gao, L; Gao, X; García-Salido, A; Gatto, R; Gautam, S; Ge, C; Ghogomu, SM; Gianesello, L; Gonçales, VR; Gooch, JL; Gooding, JJ; Gourley, GG; Gu, H; Gu, X; Gu, Z; Guerreri, M; Guillén, M; Hazzaa, SM; Heylen, E; Hicks, R; Hong, X; Hoshi, M; Hu, B; Hu, LX; Hu, R; Hu, S; Huang, J; Huang, K; Hubbard, WB; Hui, J; Hwang, NY; Iannacci, J; Ianus, A; Iglesias-Bouzas, MI; Ihara, I; Iwasaki, M; Jaeger, S; Kandel, YR; Karpińska, G; Kim, HK; Klopfenstein, TJ; Knorr, D; Koók, L; Kotb, S; Kruithof, S; Larsson, P; Laurence, C; Leng, J; Li, H; Li, J; Li, Q; Li, S; Li, X; Li, Z; Lian, J; Liang, JX; Liang, X; Lighaam, LC; Lin, CW; Lin, HC; Lin, J; Ling, A; Liu, J; Liu, P; Liu, YS; Ljuslinder, I; Lo, GH; Lodge, CJ; Löfgren-Burström, A; Lowe, AJ; Lu, M; Lu, N; Lucero-Prisno, DE; Luebbe, KM; Luo, X; Ma, Z; Maes, P; Makuch, M; Malekbala, MR; Mao, Z; Martínez-Romera, I; Marzo, G; Mathew, FM; Mattei, A; Matthijnssens, J; Mayumi, M; Morita, N; Mueller, DS; Mullangi, R; Mummolo, S; Murthi, P; Myte, R; Nabeshima, T; Nakamoto, K; Nehdi, IA; Nemestóthy, N; Niessen, HWM; Noh, JM; Nota, A; Nunes, D; Oh, D; Öhlund, D; Olsen, KM; Ono, H; Osawa, Y; Palmqvist, R; Palombo, M; Park, M; Patience, JF; Peng, Y; Perng, DS; Persano, A; Priante, G; Prince, SJ; Pulipati, S; Pyo, H; Qiu, X; Quan, J; Quaranta, F; Quinzi, V; Rademacher, CJ; Rajaraman, G; Rashid, U; Rauch, JC; Rector, A; Remmerswaal, EBM; Ren, R; Rispens, T; Rocha, GS; Saad, NM; Saito, K; Salamova, A; Sarfaraz, K; Satoshi, A; Schnellmann, RG; Scholpa, NE; Schonhoff, M; Schwartz, KJ; Schwarze, M; Schweer, WP; Seiichi, Y; Serrano-González, A; Severino, J; Shemesh, N; Shi, ZQ; Shike, DW; Shim, YM; Siciliano, PA; Siebenrock, KA; Silva, MKL; Smith, DL; Soltani, S; Song, YM; Spry, ML; Stalker, LA; Stokes, RS; Sullivan, PG; Sun, JM; Sun, S; Svanes, C; Syo, K; Tai, CM; Takashima, S; Tashita, C; Taurino, A; Ten Berge, IJM; Tenuta, AU; Teo, SH; Tilley, RD; Trivedi, RK; Umetsu, K; Unger, PA; van Bruggen, R; van Ham, SM; Van Ranst, M; Vanitha, J; Vekaria, HJ; Venier, M; Venkateshwaran, K; Venkert, A; Vermeulen, E; Wan, C; Wang, H; Wang, N; Wang, P; Wang, T; Wang, X; Wang, Y; Wise, KA; Wolbink, GJ; Wu, J; Wu, P; Wu, S; Wu, Y; Xia, Q; Xin, W; Xiong, Q; Xu, H; Xu, P; Xue, S; Yamamoto, Y; Yamashiro, T; Yan, F; Yan, H; Yan, S; Yan, Y; Yang, JM; Yang, L; Yang, P; Ye, W; Yeh, JH; Yinda, CK; Ying, GG; Ying, L; Yoon, HG; Yu, H; Zainuddin, M; Zakkula, A; Zeller, M; Zeng, Y; Zha, J; Zhang, F; Zhang, H; Zhang, M; Zhang, Q; Zhang, S; Zhang, T; Zhang, Z; Zhao, C; Zhao, J; Zhao, Y; Zhong, Q; Zhu, J; Zingmark, C; Zo, JI; Zou, Y1
Barroso, PA; Bracamonte, E; Korenaga, M; Marco, JD; Moya Álvarez, A; Sosa, AM1
Bae, HJ; Cai, M; Cho, K; Goo, N; Jeon, SJ; Jeong, Y; Jung, SY; Kim, J; Kwon, KJ; Ryu, JH1
Alemany-González, M; Dierssen, M; Gener, T; Nebot, P; Puig, MV; Vilademunt, M1
Kang, J; Oteiza, PI; Wang, Z1
Berry, DL; Cheema, A; Chung, FL; Coia, H; Cruz, MI; Girgis, M; Hou, Y; Lee, Y; Ma, N; Pannkuk, E; Permaul, E; Rodriquez, O; Zhu, Z1
Chen, X; Guo, H; Hao, S; He, R; Li, L; Li, Y; Lin, J; Lv, C; Shi, F; Song, X; Tang, H; Ye, G; Yin, Z; Zhao, L; Zou, Y1
Goodlett, CR; LaCombe, J; Patel, R; Roper, RJ; Stringer, M; Wallace, JM1
Lai, JY; Luo, LJ; Nguyen, DD1
Li, H; Lv, L; Yang, F; Yuan, J1
Du, X; Fu, X; Hou, Y; Huang, Z; Li, J; Luo, Y; Zhuan, Q1
Liu, HF; Liu, JX; Liu, ZJ; Pan, Q; Su, HY; Yang, C; Zhang, WH1
Chen, JY; Lu, JH; OuYang, D; Zhang, S; Zhu, Q1
Li, G; Lin, W; Wang, X; Yang, J; Zheng, X; Zhou, C1
Balaji, KS; Brindhadevi, K; Melappa, G; Munawer, U; Ningaraju, S; Pugazhendhi, A; Raghavendra, VB1
Catuara-Solarz, S; De Toma, I; Dierssen, M; Ortega, M; Sabidó, E; Sierra, C1
An, H; Cai, Z; Cao, J; Chen, N; Li, K; Li, Y; Luo, A; Peng, Y; Tang, Y; Tao, H1
Ahn, SY; Cho, YK; Choi, C; Jung, YS; Kwon, SW; Lee, YH; Son, Y; Song, HD; Yoon, YC1
Ceballos, G; Cordero-Anguiano, P; Gonzalez-Ruiz, C; Meaney, E; Mondragón-Lozano, R; Morales-Guadarrama, A; Nájera, N; Salgado-Ceballos, H; Sánchez-Torres, S; Villarreal, F1
Jiang, X; Li, SJ; Wang, XY; Wang, YQ; Zhuang, G1
Chen, JH; Hsu, JY; Li, TS; Lin, HH; Tseng, CY; Wong, Y1
Chen, L; Guo, Y; Li, G; Li, Z; Wan, Z; Zhu, J1
Guo, H; Hao, S; He, R; Li, L; Li, Y; Shi, F; Song, X; Tang, H; Yan, Q; Ye, G; Zhao, L; Zou, Y1
Heredia, M; Mollá, B; Sanz, P1
Almeida-Toledano, L; Andreu-Fernández, V; Aras-López, R; García-Algar, Ó; Gómez-Roig, MD; Martínez, L1
Hu, YZ; Liu, HX; Shang, P; Tang, SK; Xu, XX; Zheng, G1
Diao, Y; Hu, X; Li, L; Li, X; Liu, H; Peng, J; Xu, Q; Yin, H; Yu, J; Zhang, C; Zhang, X; Zhang, Y1
Albaigès, J; De La Torre, R; Dierssen, M; González, A; Gonzàlez, R; Llambrich, S; Martínez-Abadías, N; Sarlé, A; Sevillano, X; Sharpe, J; Starbuck, JM; Vande Velde, G; Wouters, J1
Abunofal, O; Baig, S; Du, Y; Hicks, J; Mohan, C; Paglicawan, L; Soomro, S; Vanarsa, K1
Afzal, SM; Ali, N; Islam, J; Rashid, S; Shree, A; Sultana, S; Vafa, A1
Marchat, LA; Pacheco-Yépez, J; Ramírez-Moreno, E; Rivera, G; Sánchez-Monroy, V; Shibayama-Salas, M; Silva-Olivares, A; Velásquez-Torres, M1
Ji, A; Li, J; Li, Y; Liu, Z; Wang, Y; Wu, D; Xie, Z; Zhang, Q; Zhong, P1
Abd El-Fattah, AI; Abu-Elfotuh, K; Ali, AA; Elariny, HA1
Cheng, L; Luo, ZL; Ren, JD; Sun, HY; Wu, XB1
Bergamo, P; Bessa-Pereira, C; Dias, R; Freitas, V; Luongo, D; Maurano, F; Mazzarella, G; Pérez-Gregorio, M; Rossi, M; Rotondi Aufiero, V1
Canela-Tellez, GD; Coral-Vázquez, RM; García, S; Genis-Mendoza, AD; Jiménez-Estrada, I; Martínez-Damas, MG; Nicolini-Sanchez, JH; Pérez-de la Cruz, V; Ramírez-Ramírez, M; Ramos-Chávez, LA1
Kamal, DAM; Mokhtar, MH; Salamt, N; Zaid, SSM1
Guo, J; Ji, H; Li, C; Li, S; Lian, S; Liu, Y; Lu, J; Lv, H; Ma, L; Xu, B; Yang, H1
Guo, Q; Sheng, DY; Xu, ST; Yang, P; Zhang, QZ1
Ding, F; Tian, X; Xiao, H; Xie, G; Xue, Y; Zhang, M; Zhou, Y1
Choi, SY; Kim, CE; Lee, H; Shim, W; Yang, J1
Guo, L; Guo, W; Jin, H; Li, T; Liu, X; Liu, Y; Song, Y; Sun, W; Wang, F; Wu, H; Wu, J; Yang, T; Zhang, H1
Abeysekera, I; Dria, KJ; Goodlett, CR; LaCombe, J; Roper, RJ; Stancombe, K; Stewart, RJ; Stringer, M; Thomas, J; Wallace, JM1
Bae, J; Hiroi, S; Huang, Y; Kangawa, K; Kumazoe, M; Nojiri, T; Onda, H; Tachibana, H; Takahashi, T; Takai, M; Takamatsu, K; Takeuchi, C; Tanaka, H; Yamada, S; Yamanouchi, M; Yamashita, S1
Chen, Y; Guo, Y; Nan, Y; Wang, S; Wang, X; Zhao, Y1
Fu, M; Fu, S; Hong, T; Liu, Y; Ni, S; Zou, L1
Airoldi, C; Bonanomi, M; De Gioia, L; Gatta, E; Natalello, A; Pellistri, F; Penco, A; Regonesi, ME; Relini, A; Tortora, P; Vertemara, J; Visentin, C1
Cheng, J; Jin, XL; Kim, J; Lao, WG; Lin, YG; Ong, M; Qu, XQ; Tan, Y; Xiao, L; Zhu, XQ1
Cai, Y; Huang, J; Jiang, Z; You, L; Zhang, J1
Hong, H; Li, Y; Su, B1
Inagaki, Y; Kato, E; Kawabata, J; Kurokawa, M; Kushibiki, N1
Benov, L; Khan, KM; Renno, WM1
Brandl, MB; Cirillo, G; Kavallaris, M; Kimpton, K; Kumar, N; Pasquier, E; Vittorio, O; Yee, EMH1
Gao, H; Hu, Y; Li, X; Tian, R; Wang, Y; Williams, BR; Xu, P; Yan, F; Ying, L; Zhao, Y1
Li, Y; Meeran, SM; Tollefsbol, TO1
Carpes, FP; Garcia, A; Martins, A; Mello-Carpes, PB; Schimidt, HL1
Chang, SJ; Chang, YC; Chen, YJ; Liu, HW1
Azarnia, M; Mashayekhi, F; Salehi, Z; Semnani, M1
Bimonte, S; Cascella, M; Cuomo, A; Mehrabi-Kermani, F; Schiavone, V1
Almeida, L; Andreu-Fernández, V; Aras-López, R; Martínez, L; Tovar, J1
Ceballos, G; Meaney, E; Moreno-Ulloa, A; Najera, N; Ortiz, A; Ortiz-Flores, M; Ortiz-Vilchis, P; Pacheco, M; Ramirez-Sanchez, I; Rubio-Gayosso, I; Vega, L; Villarreal, F1
Ganeshpurkar, A; Saluja, AK1
Cai, X; Shang, Y; Yang, N; Zhang, H1
Bhak, G; Lee, JT; Lee, S; Paik, SR; Park, JH; Rhoo, KY; Yang, JE1
Honda, Y; Ichihara, E; Kiura, K; Kubo, T; Murakami, T; Ninomiya, T; Ochi, N; Takigawa, N; Tanimoto, M; Yamane, H; Yasugi, M1
Cai, YK; Chen, J; Chen, WJ; Hao, Z; Lv, Y; Wang, HP; Wang, X; Ye, T; Zhao, JY1
Chen, Y; Cheng, L; Zhang, X; Zhang, Z; Zheng, X1
Baidoo, JNE; Banerjee, P; Cohen, LS; David, L; Mancuso, A; Mukherjee, S; Sampat, S; Zhou, S1
Liang, Z; Zhou, T; Zhu, M1
Liu, B; Wang, M; Wang, X1
Bing, X; Keyan, C; Linlang, L; Wanwei, D; Xuelei, L1
Jung, UJ; Kim, SR1
Govindaraj, S; Muhammed, I; Sankar, S1
Liu, D1
Cao, K; Chen, H; Fan, X; Min, X; Tu, S; Xiao, F1
Chen, D; Wang, W; Zhu, K1
Albericio, G; Borralleras, C; Bosch-Morató, M; Campuzano, V; Guivernau, B; Muñoz, FJ; Ortiz-Romero, P; Pérez-Jurado, LA1
Chuang, SM; Ho, WT; Juan, YS; Lee, YC; Lee, YL; Lin, KL; Wu, BN; Wu, WJ1
Chen, K; Chen, W; Han, Y; Hou, P; Huang, XY; Liu, SL; Qi, J; Wang, Y; Wu, TS; Yao, H; Yu, KF1
Jimenez-Del-Rio, M; Martinez-Perez, DA; Velez-Pardo, C1
Cai, M; Jiang, Q; Liu, Q; Wang, X; Wang, Y; Wu, R; Yao, Y1
He, J; Sun, M; Tian, S1
Chen, J; Liu, Q; Luo, X; Pan, Z; Ruan, Y; Wang, Q; Yan, YJ; Zhou, L; Zhou, Y1
Cai, Y; Fu, G; Fu, W; Wang, H; Zhao, H1
Abdеlaziz, RR; Suddek, GM; Еlmahdy, MK1
Alexandre, EC; André, DM; Antunes, E; Calixto, MC; Horimoto, CM1
Chen, F; Hu, L; Huang, Y; Liu, T; Sheng, J; Wang, X; Xiang, Z; Xu, H; Xu, J; Yin, D1
Fujiki, H; Iida, K; Kobayashi, Y; Namiki, K; Rawangkan, A; Shimizu, Y; Suganuma, M; Wongsirisin, P1
Chen, Q; Chen, Y; Gu, M; Liu, C; Wan, X; Wang, Z; Yang, T; Zhou, J1
Canto, P; Coral-Vázquez, RM; De Los Santos, S; Palma-Flores, C; Zentella-Dehesa, A1
Zhang, G; Zhang, J1
Guo, L; Li, J; Li, Q; Luo, X; Wu, G; Xi, J; Xue, H1
Aggarwal, R; Chakrabarti, A; Kaur, H; Kumar, B; Medhi, B; Modi, M; Radotra, BD; Sinha, VR1
Hahm, DH; Lee, B; Lee, H; Shim, I1
Gan, Y; Liu, J; Liu, L; Tian, J; Zhao, W1
Ding, L; Gao, X; Hu, J; Yu, S1
Mao, L; Wang, Y; Xu, P; Zhou, J1
Gao, D; Li, W; Ma, X; Nie, X; Wang, J; Wang, W; Xing, J; Yu, Z; Zhang, X1
Cai, H; Chen, S; Dai, J; Dong, F; Huang, YJ; Li, AL; Li, T; Li, WJ; Liu, X; Liu, ZG; Liu, ZS; Pang, X; Wang, M; Wang, X; Wu, SM; Xia, Q; Xia, T; Xing, JQ; Xue, W; Zhang, XM; Zhang, ZY; Zhao, M; Zhou, T1
Chen, KH; Chen, ZY; Chiu, WY; Huang, HY; Lin, IC; Tseng, CL; Wang, MC; Wu, CC; Yang, WV1
Ando, Y; Masuda, T; Misumi, Y; Ogura, T; Toyoshima, R; Tsuda, Y; Ueda, M; Yamanaka, K1
Chen, Z; Jiang, Z; Li, Y; Liu, L; Lu, Z; Qing, H; Yang, Q; Zhang, L; Zhang, X1
Koyama, N; Maeda, M; Mori, T; Segawa, T; Tan, J; Town, T1
Fukuhara, K; Iwai, S; Kamei, D; Karasawa, K; Murase, R; Nakano, E; Taki, I1
Hsiao, HB; Lin, WC; Wu, JB1
Gulati, A; Gupta, M; Kumari, A; Kumari, M; Padwad, Y; Sharma, A; Sharma, R1
Casanova, E; Crescenti, A; Gibert-Ramos, A; Salvadó, J1
Ano, Y; Kita, M; Kondo, K; Ohya, R; Taniguchi, Y1
Azuma, M; Dat Le, T; Hiraki, N; Inoue, YH; Omura, F; Yamanaka, M; Yoshimoto, Y1
Eisenstein, M1
Bai, S; Du, F; Fu, X; Jiao, Y; Ma, J; Wang, L; Zhou, L1
Chan, SO; Chu, KO; Chu, WK; He, JN; Hui, WK; Li, J; Ng, TK; Pang, CP; Ren, J; Yip, YWY; Yu, QX1
Bobinski, F; Buffon, LD; da Silva, GS; da Silva, TBGC; David, IMB; de Souza Fernandes, F; Dos Santos Silva Ferreira, JB; Kopper, MBR; Kviecinski, MR; Lüdtke, DD; Martins, DF; Pedrosa, RC; Zeferino, RC1
Hao, Z; Huang, Z; Ji, L; Jing, X; Sheng, Y; Wang, Z; Zhang, J1
Huang, MX; Jiang, Y; Lei, GT; Wu, QH; Xing, YW1
He, L; Liu, G1
Cui, Z; Jia, L; Qu, Z; Si, P; Sun, C; Wang, W; Xie, T; Xue, Y; Zhen, J1
Chevalier, C; Créau, N; Dairou, J; Daubigney, F; Delabar, JM; Duchon, A; Gu, Y; Herault, Y; Janel, N; Nalesso, V; Souchet, B; Yu, Y1
Auladell, C; Barenys, M; Barroso, E; Camins, A; Cano, A; Chang, JH; Espina, M; Ettcheto, M; Folch, J; García, ML; Kühne, BA; Souto, EB; Turowski, P1
Alves, GM; Assis, ALEM; Athaydes, BR; Campagnaro, BP; Gomes, JVD; Gonçalves, RCR; Kitagawa, RR; Kuster, RM; Nogueira, BV; Pereira, TMC; Rodrigues, RP; Silveira, D1
Kalantar, H; Khodayar, MJ; Mansouri, E; Pashmforoosh, M; Shariati, S1
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Chiba, M; Kawano, S; Nakagami, T; Sanada, Y; Sugiyama, A; Tajiri, T; Toki, A1
Awwad, J; Bazi, T; Hajj-Hussein, IA; Hijaz, M; Jurjus, A; Shams, A1
Chu, TC; Derossi, S; Dickinson, D; Hsu, S; Ogbureke, K; Ohno, S; Yamamoto, T; Yu, H1
Chen, K; Chen, L; Jia, Q; Li, Y; Sun, P; Wang, H; Wang, T1
Johnson, RJ; Lanaspa, MA; Maeshima, Y; Miyazaki, M; Nakagawa, T; Sato, W; Schreiner, GF; Suzuki, N; Tamura, Y; Tanabe, K; Villarreal, FJ1
Choi, DY; Han, SB; Hong, JT; Lee, YJ; Oh, KW; Yun, YP1
He, M; Huang, Q; Huang, R; Liao, M; Lin, X; Wei, L; Zhang, S; Zheng, L; Zhuo, L1
Barañao, RI; Bastón, JI; Bilotas, MA; Meresman, GF; Olivares, CN; Ricci, AG; Singla, JJ1
da Silva, EL; Hort, MA; Maraschin, M; Minatti, J; Ribeiro-do-Valle, RM; Wazlawik, E; Zaleski, FL1
Cai, Y; Chen, TT; Gao, S; Geng, B; Liu, PQ; Ye, JT; Yu, SS; Yu, Y1
Hashimoto, S; Imano, M; Ito, A; Itoh, T; Matsuo, K; Mizuguchi, N; Munakata, H; Nakayama, T; Nishida, S; Satou, T; Tabuchi, M; Tsubaki, M1
Fukui, M; Kang, KS; Wen, Y; Yamabe, N; Zhu, BT1
Stanely Mainzen Prince, P1
Anderson, J; Cantilena, S; Chayka, O; D'Alicarnasso, M; Himoudi, N; Morgenstern, DA; Pearson, K; Piotrowska, I; Sala, A; Santilli, G; Thrasher, AJ1
Sui, FX; Teng, X; Wu, YB; Yu, JF; Zhao, CG; Zhou, P1
Gupta, S; Mukhtar, H1
Arteel, GE; Froh, M; Gäbele, E; Konno, A; McKim, SE; Sies, H; Thurman, RG; Uesugi, T1
Akagi, K; Futakuchi, M; Hirose, M; Mizoguchi, Y; Shirai, T; Yamaguchi, T1
Imamura, M; Itami, A; Kaganoi, J; Kawabe, A; Komoto, I; Li, ZG; Maeda, M; Sato, F; Shimada, Y1
Matsushima, M; Sato, D1
Jung, JG; Kim, CY; Lee, JJ; Lee, SR; Lee, SY1
Beissenhirtz, M; Büttemeyer, R; Lisdat, F; Mall, JW; Philipp, AW; Schlenzka, L1
Cho, EJ; Rhyu, DY; Yokozawa, T1
Cheng, CH; Kong, LD; Wang, Y; Yang, C; Zhang, X; Zhu, JX1
Appleton, I; Hall, I; Howard, R; Kapoor, M1
Ardévol, A; Arola, L; Bladé, MC; Blay, M; Pinent, M; Salvadó, MJ1
Amit, T; Mandel, S; Weinreb, O; Youdim, MB1
Astancolle, S; Bettuzzi, S; Brausi, M; Caporali, A; Corti, A; D'Arca, D; Davalli, P1
Albini, A; Calabrese, F; Dell'Aica, I; Donà, M; Garbisa, S; Morini, M; Pezzato, E; Sartor, L1
Crespy, V; Williamson, G1
Mandel, S; Maor, G; Youdim, MB1
Campbell, C; Chavin, KD; Cheng, G; Donovan, JL; Evans, Z; Fiorini, RN; Haines, JK; Markowitz, JS; May, HD; Milliken, CE; Rodwell, D; Schmidt, MG1
Auger, C; Besançon, P; Bornet, A; Caporiccio, B; Cristol, JP; Gérain, P; Lequeux, N; Rouanet, JM; Serisier, S; Teissedre, PL1
Chopra, K; Kaur, S; Singal, A; Tirkey, N1
Abel, S; Burns, SA; Clifford, AJ; Dingley, KH; Ebeler, SE; Mitchell, AE; Steinberg, FM; Ubick, E1
Cho, YH; Han, CH; Kang, SH; Kim, SW; Lee, SJ; Lee, YS; Shin, OR; Sim, YC1
Banerjee, S; Das, S; Ganguly, C; Manna, S; Panda, CK; Saha, P1
Astancolle, S; Belloni, L; Bettuzzi, S; Caporali, A; Corti, A; Davalli, P; Remondini, D; Rizzi, F; Scaltriti, M1
Hwang, MS; Kim, HT; Kim, HY; Kim, J; Kim, MH; Kim, OH; Kim, SH; Koh, SH; Lee, KW; Lee, KY; Lee, SM; Lee, YJ; Song, C; Yang, KW1
Buetler, TM; Dorchies, OM; Kucera, P; Ruegg, UT; Vuadens, O; Wagner, S; Waldhauser, K1
Clark, J; You, M1
Chang, KW; Hsu, HC; Ko, SY; Lin, SC; Liu, TY1
Choi, IW; Kim, SH; Lee, CM; Lee, HK; Moon, DO; Park, HJ; Park, YM; Roh, HJ1
Bani, D; Ciampa, A; Giannini, L; Masini, E; Menegazzi, M; Nistri, S; Suzuki, H; Suzuki, Y1
Catapano, AL; Marchesi, P; Norata, GD; Passamonti, S; Pirillo, A; Violi, F1
Guiramand, J; Lanté, F; Maurice, T; Nedjar, M; Récasens, M; Thethi, K; Vignes, M1
Bal dit Sollier, C; Berge, N; Brézillon, C; Callebert, J; Drouet, L; Philippe, C; Rabot, S; Soulat, T; Teissedre, PL1
Choi, MS; Jang, YH; Kim, AR; Kim, JM; Lee, MY; Lee, SR; Lee, YC; Mun, KC; Park, HR; Park, NH; Shin, HY1
Chen, S; Le, W; Li, L; Li, X; Luo, G; Xu, Z1
Agbor, GA; Bose, P; Muchler, S; Proch, J; Samman, N; Shuta, D; Taffera, P; Vinson, JA1
Chiba, T; Fukuzawa, Y; Hirai, M; Hotta, Y; Ishikawa, N; Isobe, F; Kawamura, N; Nakano, A; Wakida, Y1
Aktas, O; Waiczies, S; Zipp, F1
Bollag, WB; Borke, J; Camba, AM; Dickinson, DP; Hsu, SD; Ogbureke, KU; Qin, H; Schuster, GS; Sharawy, MM; Stöppler, HJ; Winger, JN1
Gaedicke, G; Huebener, N; Lode, HN; Strandsby, A1
Hirose, M; Ishii, Y; Kanki, K; Kuroiwa, Y; Mitsumori, K; Nakazawa, H; Nishikawa, A; Umemura, T1
Cao, LQ; Chen, XL; Huang, XH; Li, W; Liu, YJ; Sun, K; Wang, Q; Zhang, LJ; Zhen, MC1
Catravas, JD; Denenberg, AG; Hake, PW; Lahni, PM; Snead, C; Wheeler, DS; Wong, HR; Zingarelli, B1
Aruoma, OI; Fujii, H; Nishioka, H; Sun, B; Tomobe, K1
Egashira, N; Egawa, T; Fujiwara, M; Irie, K; Iwasaki, K; Kitamura, Y; Mishima, K; Motohashi, K; Orito, K; Pu, F; Tanaka, Y1
Camino, A; Esteva, MI; Flawiá, MM; Güida, MC; Paveto, C; Torres, HN1
Bahcecioglu, IH; Dagli, AF; Kuzu, N; Ozercan, IH; Sahin, K; Ustündag, B1
Ju, J; Lambert, JD; Lu, G; Yang, CS1
Rao, ChV; Vijayakumar, M1
Abboud, PA; Burroughs, TJ; Hake, PW; Mangeshkar, P; O'Connor, M; Odoms, K; Wong, HR; Zingarelli, B1
Chen, Y; Lin, YZ; Song, YG1
Burckhardt, IC; Cheng, Y; Dayyat, E; Goldbart, AD; Gozal, D; Li, RC; Row, BW1
Devika, PT; Prince, PS1
Joghataie, MT; Nobakht, M; Rasoolijazi, H; Roghani, M1
Arendash, GW; Fernandez, F; Hou, H; Jensen, M; Rezai-Zadeh, K; Runfeldt, M; Shytle, RD; Tan, J1
Siegers, CP1
Akagi, K; Hara, Y; Hirose, M; Hoshiya, T; Ito, N; Takahashi, S1
Güran, Z; Kozluca, O; Kulaksiz, T; Olcay, E; Sürücü, S; Uskent, N1
German, JB; Irving, D; Rein, D; Walzem, RL; Xu, R; Yokoyama, WH1
Isogai, E; Isogai, H; Nishikawa, T; Takeshi, K1
de Villiers, WJ; McClain, CJ; Varilek, GW; Yang, F1
Sato, D1
Chung, JY; Lee, MJ; Li, C; Yang, CS; Yang, GY1
Li, J; Zhang, Y; Zhou, L1
Arakawa, Y; Matsui, T; Sato, H1
Hara, Y; Ikigai, H; Okubo, S; Shimamura, T; Suzuki, T; Suzuki, Y; Toda, M1
Ebina, T; Tsukada, K1

Reviews

38 review(s) available for catechin and Disease Models, Animal

ArticleYear
Natural polyphenols in preclinical models of epilepsy.
    Phytotherapy research : PTR, 2020, Volume: 34, Issue:6

    Topics: Animals; Catechin; Disease Models, Animal; Epilepsy; Humans; Male; Polyphenols; Quercetin; Rats; Rats, Sprague-Dawley; Resveratrol

2020
Dysplastic Aberrant Crypt Foci: Biomarkers of Early Colorectal Neoplasia and Response to Preventive Intervention.
    Cancer prevention research (Philadelphia, Pa.), 2020, Volume: 13, Issue:3

    Topics: Aberrant Crypt Foci; Adenoma; Adenomatous Polyposis Coli Protein; Animals; Antineoplastic Agents; Aspirin; Atorvastatin; Carcinogenesis; Catechin; Clinical Trials as Topic; Colon; Colonoscopy; Colorectal Neoplasms; Dietary Supplements; Disease Models, Animal; Humans; Intestinal Mucosa; Lycopene; Mice; Mutation; Treatment Outcome

2020
    Computational & theoretical chemistry, 2013, Feb-01, Volume: 1005

    Topics: Acetaminophen; Administration, Oral; Adolescent; Adsorption; Adult; Allyl Compounds; Amylopectin; Amylose; Anaerobiosis; Animals; Anti-Bacterial Agents; Anura; Arginase; Arthritis, Rheumatoid; Asthma; Atmosphere; B-Lymphocytes; Basic Helix-Loop-Helix Transcription Factors; Bioelectric Energy Sources; Biofilms; Biofuels; Biomarkers; Biopolymers; Bioreactors; Brain; Brain Injuries, Traumatic; Breast Neoplasms; Calibration; Carbon Tetrachloride; Caspase 3; Catalysis; Catechin; Cations; Cattle; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Cell Body; Cell Line, Tumor; Cell Plasticity; Chemical and Drug Induced Liver Injury; Chemistry Techniques, Synthetic; China; Chitosan; Chloride Channels; Chromatography, High Pressure Liquid; Chromosome Mapping; Cognition; Cognitive Dysfunction; Cohort Studies; Colitis, Ulcerative; Colloids; Coloring Agents; Congresses as Topic; Correlation of Data; Crystallization; Cyanoacrylates; Cyclohexane Monoterpenes; Cyprinidae; Cytochrome P-450 CYP1A1; Death, Sudden; Dent Disease; Dietary Supplements; Diffusion Magnetic Resonance Imaging; Disease Models, Animal; Disease Progression; Disease Resistance; Disulfides; Drug Monitoring; Drug Stability; Ecotoxicology; Electricity; Electrodes; Endocytosis; Environmental Exposure; Environmental Monitoring; Enzyme Inhibitors; Epithelial-Mesenchymal Transition; Esophageal and Gastric Varices; Esters; Fagopyrum; Female; Ferrosoferric Oxide; Flame Retardants; Flavobacteriaceae; Flow Cytometry; Follow-Up Studies; Formoterol Fumarate; Fusarium; Garlic; Gastrointestinal Hemorrhage; Gene Expression; Genes, Plant; Genetic Markers; Glial Fibrillary Acidic Protein; Gliosis; Global Health; Glutathione Transferase; Glycine max; Gum Arabic; Hemostasis, Endoscopic; Hepatocytes; Hippocampus; Humans; Hydrogen-Ion Concentration; Illinois; Immunoglobulin G; Indoleamine-Pyrrole 2,3,-Dioxygenase; Infant, Newborn; Infant, Small for Gestational Age; Injections, Intraperitoneal; Interleukin-4; Iowa; Iron; Ki-67 Antigen; Kidney; Kinetics; Kynurenine; Lakes; Levofloxacin; Lipid Peroxidation; Lipids; Liver; Liver Cirrhosis, Experimental; Magnetic Fields; Magnetic Iron Oxide Nanoparticles; Male; Manure; Maze Learning; Memory, Short-Term; Metal Nanoparticles; Metals, Heavy; Methane; Mice; Mice, Inbred C57BL; Mice, Knockout; Michigan; Microalgae; Microbial Consortia; Mitochondria; Models, Animal; Models, Chemical; Models, Neurological; Molecular Structure; Molecular Weight; Mutation; Myeloid-Derived Suppressor Cells; NADPH Oxidase 2; Neoplasm Recurrence, Local; Neurites; Neurons; Neuroprotective Agents; NF-kappa B; NIH 3T3 Cells; Nitric Oxide Synthase Type II; Nitrogen; Ohio; Ointments; Ontario; Organelle Biogenesis; Organophosphates; Organophosphorus Compounds; Oxidative Stress; Palladium; Particle Size; Pectins; Phenotype; Phytotherapy; Piperidines; Placenta; Plant Diseases; Plant Extracts; Polymers; Polymorphism, Genetic; Polyphenols; Powders; Pregnancy; Pregnancy Trimester, First; Prospective Studies; Protein Kinase Inhibitors; Protein Structure, Secondary; Proteins; Pyridines; Pyrimidines; Rats, Wistar; Real-Time Polymerase Chain Reaction; Receptors, Aryl Hydrocarbon; Receptors, Chemokine; Receptors, Formyl Peptide; Receptors, Lipoxin; Recovery of Function; Recurrence; Reference Standards; Reference Values; Reproducibility of Results; Respiratory Function Tests; Retrospective Studies; Risk; Sensitivity and Specificity; Sewage; Signal Transduction; Sodium Glutamate; Soil; Solanum tuberosum; Solubility; Solutions; Spectroscopy, Fourier Transform Infrared; Spectrum Analysis; Spermatozoa; STAT3 Transcription Factor; Sulfamethoxazole; Tea; Temperature; Thermodynamics; Thrombin; Treatment Outcome; Triazoles; United States; Viscosity; Waste Disposal, Fluid; Wastewater; Water; Water Pollutants, Chemical; Water Purification; White Matter; Wisconsin; X-Ray Diffraction; Zea mays

2013
The pharmacological activity of epigallocatechin-3-gallate (EGCG) on Alzheimer's disease animal model: A systematic review.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2020, Volume: 79

    Topics: Alzheimer Disease; Amyloid Precursor Protein Secretases; Animals; Antioxidants; Blood-Brain Barrier; Catechin; Cognition; Disease Models, Animal; Humans; Neuroprotective Agents; Phosphorylation

2020
Beneficial Effects of Green Tea Catechins on Female Reproductive Disorders: A Review.
    Molecules (Basel, Switzerland), 2021, May-03, Volume: 26, Issue:9

    Topics: Angiogenesis Inhibitors; Animals; Antioxidants; Apoptosis; Camellia sinensis; Catechin; Cell Proliferation; Corticosterone; Cross-Sectional Studies; Disease Models, Animal; Dysmenorrhea; Endometriosis; Female; Humans; Mice; Plant Extracts; Polycystic Ovary Syndrome; Tea; Uterus

2021
The roles of epigallocatechin-3-gallate in the treatment of neuropathic pain: an update on preclinical in vivo studies and future perspectives.
    Drug design, development and therapy, 2017, Volume: 11

    Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Camellia sinensis; Catechin; Disease Models, Animal; Drug Evaluation, Preclinical; Humans; Neuralgia

2017
Beneficial Effects of Flavonoids Against Parkinson's Disease.
    Journal of medicinal food, 2018, Volume: 21, Issue:5

    Topics: Animals; Anthocyanins; Antioxidants; Antiparkinson Agents; Catechin; Cell Line; Corpus Striatum; Disease Models, Animal; Dopamine; Flavanones; Flavones; Flavonoids; Flavonols; Humans; Isoflavones; Kaempferols; Neuroprotective Agents; Oxidative Stress; Parkinson Disease

2018
Epigallocatechin Gallate Modulates Muscle Homeostasis in Type 2 Diabetes and Obesity by Targeting Energetic and Redox Pathways: A Narrative Review.
    International journal of molecular sciences, 2019, Jan-27, Volume: 20, Issue:3

    Topics: Animals; Catechin; Diabetes Mellitus, Type 2; Disease Models, Animal; Energy Metabolism; Epigenesis, Genetic; Glucose; Homeostasis; Humans; Lipid Metabolism; Muscle, Skeletal; NF-kappa B; Obesity; Oxidative Stress; Signal Transduction

2019
Chemopreventive and therapeutic potential of tea polyphenols in hepatocellular cancer.
    Nutrition and cancer, 2013, Volume: 65, Issue:3

    Topics: Animals; Anti-Inflammatory Agents; Anticarcinogenic Agents; Antioxidants; Biological Availability; Catechin; Chemoprevention; Disease Models, Animal; Humans; Liver Neoplasms; Mice; Polyphenols; Tea; Xenograft Model Antitumor Assays

2013
Polyphenols: benefits to the cardiovascular system in health and in aging.
    Nutrients, 2013, Sep-26, Volume: 5, Issue:10

    Topics: Aging; Animals; Cardiovascular System; Catechin; Curcumin; Diet; Disease Models, Animal; Fruit; Heart Diseases; Humans; Olive Oil; Plant Oils; Polyphenols; Quercetin; Randomized Controlled Trials as Topic; Reactive Oxygen Species; Resveratrol; Stilbenes

2013
Prenatal treatment of Down syndrome: a reality?
    Current opinion in obstetrics & gynecology, 2014, Volume: 26, Issue:2

    Topics: Animals; Animals, Newborn; Apigenin; Catechin; Choline; Disease Models, Animal; Down Syndrome; Dyrk Kinases; Female; Fluoxetine; Humans; Mice; Mice, Transgenic; Molecular Targeted Therapy; Neural Stem Cells; Neurogenesis; Neuroprotective Agents; Oxidative Stress; Pregnancy; Prenatal Care; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Receptors, GABA; Receptors, N-Methyl-D-Aspartate; Signal Transduction; Stem Cell Transplantation

2014
Periodontal pathogens and atherosclerosis: implications of inflammation and oxidative modification of LDL.
    BioMed research international, 2014, Volume: 2014

    Topics: Aggregatibacter actinomycetemcomitans; Animals; Apolipoproteins E; Atherosclerosis; Catechin; Disease Models, Animal; Humans; Inflammation; Mice; Oxidative Stress; Periodontal Diseases; Periodontium; Porphyromonas gingivalis

2014
Dietary polyphenols regulate endothelial function and prevent cardiovascular disease.
    Nutrition (Burbank, Los Angeles County, Calif.), 2015, Volume: 31, Issue:1

    Topics: Administration, Oral; Animals; Apigenin; Aryldialkylphosphatase; Cardiovascular Diseases; Catechin; Diet; Disease Models, Animal; Endothelial Cells; Endothelin-1; Humans; Lipoproteins, HDL; Nitric Oxide; Nitric Oxide Synthase Type III; Polyphenols; Signal Transduction; U937 Cells

2015
A Review: Phytochemicals Targeting JAK/STAT Signaling and IDO Expression in Cancer.
    Phytotherapy research : PTR, 2015, Volume: 29, Issue:6

    Topics: Animals; Catechin; Cell Proliferation; Cucurbitacins; Curcumin; Disease Models, Animal; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Janus Kinases; Neoplasms; Phytochemicals; Resveratrol; Signal Transduction; STAT Transcription Factors; Stilbenes

2015
Potential Role of (-)-Epigallocatechin-3-Gallate (EGCG) in the Secondary Prevention of Alzheimer Disease.
    Current drug targets, 2017, Volume: 18, Issue:2

    Topics: Alzheimer Disease; Animals; Catechin; Clinical Trials as Topic; Disease Models, Animal; Humans; Neuroprotective Agents; Oxidative Stress; Secondary Prevention; Treatment Outcome

2017
Black tea: Phytochemicals, cancer chemoprevention, and clinical studies.
    Critical reviews in food science and nutrition, 2017, May-03, Volume: 57, Issue:7

    Topics: Amino Acids; Animals; Antimutagenic Agents; Antineoplastic Agents; Antioxidants; Catechin; Cell Line, Tumor; Chemoprevention; Clinical Studies as Topic; Disease Models, Animal; Flavonoids; Gene Expression Regulation, Neoplastic; Humans; Neoplasms; Phytochemicals; Polyphenols; Tea; Volatile Organic Compounds

2017
Mechanisms of body weight reduction and metabolic syndrome alleviation by tea.
    Molecular nutrition & food research, 2016, Volume: 60, Issue:1

    Topics: Adipose Tissue; AMP-Activated Protein Kinases; Animals; Camellia sinensis; Cardiovascular Diseases; Catechin; Diabetes Mellitus, Type 2; Disease Models, Animal; Humans; Liver; Meta-Analysis as Topic; Metabolic Syndrome; Muscle, Skeletal; Plant Leaves; Polyphenols; Randomized Controlled Trials as Topic; Risk Factors; Tea; Weight Loss

2016
Combination chemoprevention with grape antioxidants.
    Molecular nutrition & food research, 2016, Volume: 60, Issue:6

    Topics: Animals; Anthocyanins; Anticarcinogenic Agents; Antineoplastic Combined Chemotherapy Protocols; Antioxidants; Catechin; Cell Line, Tumor; Chemoprevention; Disease Models, Animal; Humans; Kaempferols; Neoplasms; Plant Extracts; Polyphenols; Quercetin; Resveratrol; Stilbenes; Vitis

2016
Prevention and treatment of cancers by immune modulating nutrients.
    Molecular nutrition & food research, 2016, Volume: 60, Issue:6

    Topics: Animals; Arginine; Catechin; Cell Line, Tumor; Diet; Disease Models, Animal; Fatty Acids, Unsaturated; Glutamine; Humans; Isothiocyanates; Lignans; Meta-Analysis as Topic; Micronutrients; Neoplasms; Observational Studies as Topic; Phytochemicals; Polyphenols; Randomized Controlled Trials as Topic; Stilbenes

2016
Impact of nanotechnology on the delivery of natural products for cancer prevention and therapy.
    Molecular nutrition & food research, 2016, Volume: 60, Issue:6

    Topics: Animals; Anticarcinogenic Agents; Biological Products; Catechin; Cell Line, Tumor; Chemoprevention; Curcumin; Disease Models, Animal; Humans; Nanoparticles; Nanotechnology; Neoplasms; Resveratrol; Stilbenes

2016
Targeting cancer stem-like cells using dietary-derived agents - Where are we now?
    Molecular nutrition & food research, 2016, Volume: 60, Issue:6

    Topics: Animals; Anticarcinogenic Agents; Catechin; Cell Line, Tumor; Curcumin; Diet; Disease Models, Animal; Flavonoids; Humans; Isothiocyanates; Neoplasms; Neoplastic Stem Cells; Randomized Controlled Trials as Topic; Resveratrol; Stilbenes; Sulfoxides; Vitamin A

2016
Nutritional Epigenetics and the Prevention of Hepatocellular Carcinoma with Bioactive Food Constituents.
    Nutrition and cancer, 2016, Volume: 68, Issue:5

    Topics: Animals; Butyric Acid; Carcinoma, Hepatocellular; Catechin; Cell Line, Tumor; Curcumin; Disease Models, Animal; DNA Methylation; Epigenesis, Genetic; Food; Humans; Isothiocyanates; Phytochemicals; Resveratrol; Stilbenes; Sulfoxides

2016
Therapeutic potential of green tea on risk factors for type 2 diabetes in obese adults - a review.
    Obesity reviews : an official journal of the International Association for the Study of Obesity, 2016, Volume: 17, Issue:12

    Topics: Animals; Antioxidants; Body Composition; Catechin; Diabetes Mellitus, Type 2; Disease Models, Animal; Humans; Inflammation; Insulin Resistance; Meta-Analysis as Topic; Obesity; Oxidative Stress; Phytotherapy; Randomized Controlled Trials as Topic; Risk Factors; Tea

2016
Anticancer Efficacy of Polyphenols and Their Combinations.
    Nutrients, 2016, Sep-09, Volume: 8, Issue:9

    Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Ascorbic Acid; Biological Availability; Catechin; Cell Line, Tumor; Cell Proliferation; Curcumin; Disease Models, Animal; Humans; Micronutrients; Neoplasms; Plant Extracts; Polyphenols; Quercetin; Resveratrol; Stilbenes; Tea

2016
Catechins and Its Role in Chronic Diseases.
    Advances in experimental medicine and biology, 2016, Volume: 929

    Topics: Animals; Antineoplastic Agents, Phytogenic; Cardiovascular Agents; Catechin; Chronic Disease; Disease Models, Animal; Drug Discovery; Humans; Molecular Structure; Neuroprotective Agents; Phytotherapy; Plant Extracts; Plants, Medicinal; Signal Transduction; Structure-Activity Relationship; Tea

2016
Cancer chemoprevention and mitochondria: targeting apoptosis in transformed cells via the disruption of mitochondrial bioenergetics/redox state.
    Molecular nutrition & food research, 2009, Volume: 53, Issue:1

    Topics: Animals; Apoptosis; Capsaicin; Catechin; Chemoprevention; Disease Models, Animal; Humans; Mitochondrial Membranes; Neoplasms; Permeability; Reactive Oxygen Species; Resveratrol; Stilbenes; Tea

2009
Tea polyphenols regulate key mediators on inflammatory cardiovascular diseases.
    Mediators of inflammation, 2009, Volume: 2009

    Topics: Animals; Cardiovascular Diseases; Catechin; Disease Models, Animal; Flavonoids; Humans; Immunohistochemistry; Inflammation; Mice; Models, Biological; NF-kappa B; Nitric Oxide; Phenols; Polyphenols; Rats; Signal Transduction; Tea

2009
Green tea and heart health.
    Journal of cardiovascular pharmacology, 2009, Volume: 54, Issue:5

    Topics: Animals; Atherosclerosis; Camellia sinensis; Cardiovascular Diseases; Catechin; Cell Adhesion Molecules; Cytokines; Disease Models, Animal; Humans; Lipoproteins, LDL; Oxidation-Reduction; Tea

2009
Tea, flavonoids and stroke in man and mouse.
    Archives of biochemistry and biophysics, 2010, Sep-01, Volume: 501, Issue:1

    Topics: Animals; Catechin; Disease Models, Animal; Flavonoids; Glutamates; Humans; Mice; Neuroprotective Agents; Stroke; Tea

2010
[New perspectives on molecular and genic therapies in Down syndrome].
    Medecine sciences : M/S, 2010, Volume: 26, Issue:4

    Topics: Animals; Catechin; Chromosomes, Human, Pair 21; Disease Models, Animal; Down Syndrome; Droxidopa; Drug Delivery Systems; Fluoxetine; Forecasting; Gene Expression Regulation; Genetic Association Studies; Genetic Therapy; Hedgehog Proteins; Humans; Memantine; Mice; Mice, Transgenic; Models, Genetic; Neuronal Plasticity; Neurotransmitter Agents; Pentylenetetrazole; Phenotype; Signal Transduction

2010
Targeting cell signaling and apoptotic pathways by dietary agents: role in the prevention and treatment of cancer.
    Nutrition and cancer, 2011, Volume: 63, Issue:2

    Topics: Animals; Anticarcinogenic Agents; Antineoplastic Agents, Phytogenic; Apoptosis; Catechin; Clinical Trials as Topic; Curcuma; Curcumin; Diet; Disease Models, Animal; Fruit; Genistein; Humans; Neoplasms; Resveratrol; Signal Transduction; Silymarin; Stilbenes; United States; Vegetables

2011
Cardiovascular effects of green tea catechins: progress and promise.
    Recent patents on cardiovascular drug discovery, 2012, Volume: 7, Issue:2

    Topics: Animals; Antioxidants; Cardiotonic Agents; Cardiovascular Diseases; Cardiovascular System; Catechin; Cell Proliferation; Clinical Trials as Topic; Disease Models, Animal; Fibrinolytic Agents; Humans; Inflammation; Models, Cardiovascular; Platelet Aggregation; Signal Transduction; Tea

2012
Neurological mechanisms of green tea polyphenols in Alzheimer's and Parkinson's diseases.
    The Journal of nutritional biochemistry, 2004, Volume: 15, Issue:9

    Topics: Alzheimer Disease; Animals; Antioxidants; Apoptosis; Catechin; Dietary Supplements; Disease Models, Animal; Flavonoids; Gene Expression Regulation; Humans; Iron Chelating Agents; Neuroprotective Agents; Parkinson Disease; Phenols; Polyphenols; Signal Transduction; Tea

2004
A review of the health effects of green tea catechins in in vivo animal models.
    The Journal of nutrition, 2004, Volume: 134, Issue:12 Suppl

    Topics: Animals; Antioxidants; Cardiovascular Diseases; Catechin; Disease Models, Animal; Enzymes; Hormones; Kidney Diseases; Neoplasms, Experimental; Oxidative Stress; Tea

2004
Chemoprevention of lung cancer by tea.
    Molecular nutrition & food research, 2006, Volume: 50, Issue:2

    Topics: Animals; Antioxidants; Apoptosis; Catechin; Cell Division; Chemoprevention; Disease Models, Animal; Female; Flavonoids; Humans; Lung Neoplasms; Male; Phenols; Polyphenols; Tea; Tumor Necrosis Factor-alpha

2006
Neurodegeneration in autoimmune demyelination: recent mechanistic insights reveal novel therapeutic targets.
    Journal of neuroimmunology, 2007, Volume: 184, Issue:1-2

    Topics: Acyl Coenzyme A; Animals; Catechin; Disease Models, Animal; Encephalomyelitis, Autoimmune, Experimental; Humans; Multiple Sclerosis; Nerve Degeneration; Neuroprotective Agents; T-Lymphocytes; TNF-Related Apoptosis-Inducing Ligand

2007
Inhibition of carcinogenesis by tea constituents.
    Seminars in cancer biology, 2007, Volume: 17, Issue:5

    Topics: Animals; Anticarcinogenic Agents; Catechin; Cell Transformation, Neoplastic; Disease Models, Animal; Flavonoids; Humans; Neoplasms; Phenols; Polyphenols; Tea

2007
Tea and tea polyphenols in cancer prevention.
    Advances in experimental medicine and biology, 2001, Volume: 492

    Topics: Animals; Biological Availability; Caffeine; Catechin; Disease Models, Animal; Flavonoids; Humans; Intestinal Absorption; Neoplasms; Phenols; Polymers; Structure-Activity Relationship; Tea; Tissue Distribution; Tumor Cells, Cultured

2001

Trials

5 trial(s) available for catechin and Disease Models, Animal

ArticleYear
    Computational & theoretical chemistry, 2013, Feb-01, Volume: 1005

    Topics: Acetaminophen; Administration, Oral; Adolescent; Adsorption; Adult; Allyl Compounds; Amylopectin; Amylose; Anaerobiosis; Animals; Anti-Bacterial Agents; Anura; Arginase; Arthritis, Rheumatoid; Asthma; Atmosphere; B-Lymphocytes; Basic Helix-Loop-Helix Transcription Factors; Bioelectric Energy Sources; Biofilms; Biofuels; Biomarkers; Biopolymers; Bioreactors; Brain; Brain Injuries, Traumatic; Breast Neoplasms; Calibration; Carbon Tetrachloride; Caspase 3; Catalysis; Catechin; Cations; Cattle; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Cell Body; Cell Line, Tumor; Cell Plasticity; Chemical and Drug Induced Liver Injury; Chemistry Techniques, Synthetic; China; Chitosan; Chloride Channels; Chromatography, High Pressure Liquid; Chromosome Mapping; Cognition; Cognitive Dysfunction; Cohort Studies; Colitis, Ulcerative; Colloids; Coloring Agents; Congresses as Topic; Correlation of Data; Crystallization; Cyanoacrylates; Cyclohexane Monoterpenes; Cyprinidae; Cytochrome P-450 CYP1A1; Death, Sudden; Dent Disease; Dietary Supplements; Diffusion Magnetic Resonance Imaging; Disease Models, Animal; Disease Progression; Disease Resistance; Disulfides; Drug Monitoring; Drug Stability; Ecotoxicology; Electricity; Electrodes; Endocytosis; Environmental Exposure; Environmental Monitoring; Enzyme Inhibitors; Epithelial-Mesenchymal Transition; Esophageal and Gastric Varices; Esters; Fagopyrum; Female; Ferrosoferric Oxide; Flame Retardants; Flavobacteriaceae; Flow Cytometry; Follow-Up Studies; Formoterol Fumarate; Fusarium; Garlic; Gastrointestinal Hemorrhage; Gene Expression; Genes, Plant; Genetic Markers; Glial Fibrillary Acidic Protein; Gliosis; Global Health; Glutathione Transferase; Glycine max; Gum Arabic; Hemostasis, Endoscopic; Hepatocytes; Hippocampus; Humans; Hydrogen-Ion Concentration; Illinois; Immunoglobulin G; Indoleamine-Pyrrole 2,3,-Dioxygenase; Infant, Newborn; Infant, Small for Gestational Age; Injections, Intraperitoneal; Interleukin-4; Iowa; Iron; Ki-67 Antigen; Kidney; Kinetics; Kynurenine; Lakes; Levofloxacin; Lipid Peroxidation; Lipids; Liver; Liver Cirrhosis, Experimental; Magnetic Fields; Magnetic Iron Oxide Nanoparticles; Male; Manure; Maze Learning; Memory, Short-Term; Metal Nanoparticles; Metals, Heavy; Methane; Mice; Mice, Inbred C57BL; Mice, Knockout; Michigan; Microalgae; Microbial Consortia; Mitochondria; Models, Animal; Models, Chemical; Models, Neurological; Molecular Structure; Molecular Weight; Mutation; Myeloid-Derived Suppressor Cells; NADPH Oxidase 2; Neoplasm Recurrence, Local; Neurites; Neurons; Neuroprotective Agents; NF-kappa B; NIH 3T3 Cells; Nitric Oxide Synthase Type II; Nitrogen; Ohio; Ointments; Ontario; Organelle Biogenesis; Organophosphates; Organophosphorus Compounds; Oxidative Stress; Palladium; Particle Size; Pectins; Phenotype; Phytotherapy; Piperidines; Placenta; Plant Diseases; Plant Extracts; Polymers; Polymorphism, Genetic; Polyphenols; Powders; Pregnancy; Pregnancy Trimester, First; Prospective Studies; Protein Kinase Inhibitors; Protein Structure, Secondary; Proteins; Pyridines; Pyrimidines; Rats, Wistar; Real-Time Polymerase Chain Reaction; Receptors, Aryl Hydrocarbon; Receptors, Chemokine; Receptors, Formyl Peptide; Receptors, Lipoxin; Recovery of Function; Recurrence; Reference Standards; Reference Values; Reproducibility of Results; Respiratory Function Tests; Retrospective Studies; Risk; Sensitivity and Specificity; Sewage; Signal Transduction; Sodium Glutamate; Soil; Solanum tuberosum; Solubility; Solutions; Spectroscopy, Fourier Transform Infrared; Spectrum Analysis; Spermatozoa; STAT3 Transcription Factor; Sulfamethoxazole; Tea; Temperature; Thermodynamics; Thrombin; Treatment Outcome; Triazoles; United States; Viscosity; Waste Disposal, Fluid; Wastewater; Water; Water Pollutants, Chemical; Water Purification; White Matter; Wisconsin; X-Ray Diffraction; Zea mays

2013
A phase 1, randomized double-blind, placebo controlled trial to evaluate safety and efficacy of epigallocatechin-3-gallate and cognitive training in adults with Fragile X syndrome.
    Clinical nutrition (Edinburgh, Scotland), 2020, Volume: 39, Issue:2

    Topics: Adult; Animals; Catechin; Cognition Disorders; Disease Models, Animal; Double-Blind Method; Female; Fragile X Syndrome; Humans; Male; Mice; Mice, Knockout; Middle Aged; Neuroprotective Agents; Treatment Outcome; Young Adult

2020
Epigallocatechin-3-gallate, a DYRK1A inhibitor, rescues cognitive deficits in Down syndrome mouse models and in humans.
    Molecular nutrition & food research, 2014, Volume: 58, Issue:2

    Topics: Adolescent; Adult; Animals; Biomarkers; Catechin; Chromosomes, Human, Pair 16; Cognition; Disease Models, Animal; Double-Blind Method; Down Syndrome; Dyrk Kinases; Female; Gene Expression Regulation; Hippocampus; Humans; Male; Mice; Mice, Transgenic; Mosaicism; Phosphorylation; Pilot Projects; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Trisomy; Young Adult

2014
The effect of procyanidin on expression of STAT1 in type 2 diabetes mellitus SD rats with focal cerebral ischemia.
    Neuro endocrinology letters, 2014, Volume: 35, Issue:1

    Topics: Animals; Apoptosis; Biflavonoids; Brain Ischemia; Catechin; Diabetes Mellitus, Type 2; Disease Models, Animal; Gene Expression Regulation; Janus Kinases; Male; Neuroprotective Agents; Proanthocyanidins; Rats; Rats, Sprague-Dawley; Signal Transduction; STAT1 Transcription Factor

2014
A novel treatment of cystic fibrosis acting on-target: cysteamine plus epigallocatechin gallate for the autophagy-dependent rescue of class II-mutated CFTR.
    Cell death and differentiation, 2016, Volume: 23, Issue:8

    Topics: Adolescent; Animals; Autophagy; Biomarkers; Catechin; Child; Cysteamine; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Disease Models, Animal; Drug Therapy, Combination; Homozygote; Humans; Interleukin-8; Lung; Mice; Mice, Knockout; Mutation; Sputum; Tumor Necrosis Factor-alpha

2016

Other Studies

421 other study(ies) available for catechin and Disease Models, Animal

ArticleYear
Constituents of the bark and twigs of Artocarpus dadah with cyclooxygenase inhibitory activity.
    Journal of natural products, 2002, Volume: 65, Issue:2

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Acetylation; Animals; Benzofurans; Breast; Catechin; Cell Transformation, Neoplastic; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Disease Models, Animal; Indonesia; Isoenzymes; Membrane Proteins; Methylation; Mice; Mice, Inbred BALB C; Molecular Structure; Moraceae; Nuclear Magnetic Resonance, Biomolecular; Organ Culture Techniques; Plant Bark; Plant Extracts; Plant Shoots; Plants, Medicinal; Prostaglandin-Endoperoxide Synthases; Spectroscopy, Fourier Transform Infrared; Stereoisomerism; Stilbenes

2002
Inhibition of natriuretic peptide receptor 1 reduces itch in mice.
    Science translational medicine, 2019, 07-10, Volume: 11, Issue:500

    Topics: Animals; Behavior, Animal; Cell-Free System; Dermatitis, Contact; Disease Models, Animal; Ganglia, Spinal; Humans; Mice, Inbred C57BL; Mice, Knockout; Neurons; Pruritus; Receptors, Atrial Natriuretic Factor; Reproducibility of Results; Signal Transduction; Small Molecule Libraries

2019
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
    Proceedings of the National Academy of Sciences of the United States of America, 2020, 12-08, Volume: 117, Issue:49

    Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Drug Evaluation, Preclinical; High-Throughput Screening Assays; Immunocompetence; Inhibitory Concentration 50; Methacycline; Mice, Inbred C57BL; Protease Inhibitors; Quantitative Structure-Activity Relationship; Small Molecule Libraries; Vero Cells; Zika Virus; Zika Virus Infection

2020
Epigallocatechin gallate (EGCG) attenuates staphylococcal alpha-hemolysin (Hla)-induced NLRP3 inflammasome activation via ROS-MAPK pathways and EGCG-Hla interactions.
    International immunopharmacology, 2021, Volume: 100

    Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Bacterial Proteins; Catechin; Disease Models, Animal; Hemolysin Proteins; Hemolysis; Humans; Inflammasomes; Male; Mice, Inbred C57BL; Mitogen-Activated Protein Kinases; NLR Family, Pyrin Domain-Containing 3 Protein; Oxidative Stress; Reactive Oxygen Species; Signal Transduction; Staphylococcal Infections; Staphylococcus aureus; THP-1 Cells

2021
Effect of (-)-Epigallocatechin Gallate on Activation of JAK/STAT Signaling Pathway by Staphylococcal Enterotoxin A.
    Toxins, 2021, 08-29, Volume: 13, Issue:9

    Topics: Animals; Catechin; Cells, Cultured; Disease Models, Animal; Enterotoxins; Gene Expression Regulation, Bacterial; Humans; Janus Kinases; Mice; Signal Transduction; Spleen; Staphylococcus aureus; STAT3 Transcription Factor

2021
Epigallocatechin gallate (EGCG) attenuates myocardial hypertrophy and fibrosis induced by transverse aortic constriction via inhibiting the Akt/mTOR pathway.
    Pharmaceutical biology, 2021, Volume: 59, Issue:1

    Topics: Animals; Cardiomegaly; Cardiotonic Agents; Catechin; Disease Models, Animal; Dose-Response Relationship, Drug; Fibrosis; Male; Mice; Mice, Inbred C57BL; Proto-Oncogene Proteins c-akt; TOR Serine-Threonine Kinases

2021
Alpinia officinarum water extract inhibits the atopic dermatitis-like responses in NC/Nga mice by regulation of inflammatory chemokine production.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2021, Volume: 144

    Topics: Alpinia; Animals; Anti-Inflammatory Agents; Antigens, Dermatophagoides; Arthropod Proteins; Catechin; Chemokines; Dermatitis, Atopic; Dermatophagoides farinae; Disease Models, Animal; Flavonoids; HaCaT Cells; Humans; Hydroxybenzoates; Keratinocytes; Male; Mice; Plant Extracts; Signal Transduction; Skin; Solvents; Water

2021
EGCG protects against myocardial I/RI by regulating lncRNA Gm4419-mediated epigenetic silencing of the DUSP5/ERK1/2 axis.
    Toxicology and applied pharmacology, 2021, 12-15, Volume: 433

    Topics: Animals; Autophagy; Catechin; Cells, Cultured; Disease Models, Animal; Dual-Specificity Phosphatases; Enhancer of Zeste Homolog 2 Protein; Epigenesis, Genetic; Gene Silencing; Hydrogen Peroxide; Male; Mice, Inbred C57BL; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Myocardial Reperfusion Injury; Myocytes, Cardiac; RNA, Long Noncoding; Signal Transduction

2021
Restorative potential of (-)-epicatechin in a rat model of Gulf War illness muscle atrophy and fatigue.
    Scientific reports, 2021, 11-08, Volume: 11, Issue:1

    Topics: Animals; Catechin; Dietary Supplements; Disease Models, Animal; Fatigue; Humans; Male; Metabolome; Muscle Development; Muscle, Skeletal; Muscular Atrophy; Persian Gulf Syndrome; Rats; Rats, Wistar

2021
EGCG prevents pressure overload‑induced myocardial remodeling by downregulating overexpression of HDAC5 in mice.
    International journal of molecular medicine, 2022, Volume: 49, Issue:1

    Topics: Acetylation; Animals; Atrial Natriuretic Factor; Atrial Remodeling; Catechin; Constriction; Disease Models, Animal; Electrocardiography; Heart Failure; Histone Deacetylases; Histones; Lysine; Male; MEF2 Transcription Factors; Natriuretic Peptide, Brain; Survival Rate; Ventricular Remodeling

2022
Epigallocatechin Gallate (EGCG), a Green Tea Polyphenol, Reduces Coronavirus Replication in a Mouse Model.
    Viruses, 2021, 12-17, Volume: 13, Issue:12

    Topics: Animals; Antiviral Agents; Catechin; Cell Line; Coronavirus Infections; Coronavirus OC43, Human; Disease Models, Animal; Humans; Mice; Polyphenols; Tea; Virus Replication

2021
Treg/Th17 Ratio Regulation May Play an Important Role in Epigallocatechin-3-Gallate-Mediated Attenuation of Increased Afterload-Induced Cardiac Hypertrophy.
    Journal of cardiovascular pharmacology, 2022, 05-01, Volume: 79, Issue:5

    Topics: Animals; Cardiomegaly; Catechin; Disease Models, Animal; Eosine Yellowish-(YS); Hematoxylin; Male; Mice; Mice, Inbred C57BL; T-Lymphocytes, Regulatory; Th17 Cells; Wheat Germ Agglutinins

2022
Synergistic alleviation effects of anchovy hydrolysates-catechin on scopolamine-induced mice memory deficits: the exploration of the potential relationship among gut-brain-axis.
    Food & function, 2022, Feb-07, Volume: 13, Issue:3

    Topics: Animals; Behavior, Animal; Catechin; Disease Models, Animal; Fish Oils; Fishes; Functional Food; Gastrointestinal Microbiome; Male; Memory Disorders; Mice; Mice, Inbred BALB C; Neuroprotective Agents; Protein Hydrolysates; Scopolamine; Specific Pathogen-Free Organisms

2022
Transcriptome analysis provides insight into the anti-diabetic mechanism of theaflavins in high-fat diet and streptozotocin-induced mice.
    Food & function, 2022, Feb-21, Volume: 13, Issue:4

    Topics: Animals; Antioxidants; Biflavonoids; Blood Glucose; Catechin; Diabetes Mellitus, Type 2; Diet, High-Fat; Disease Models, Animal; Gene Expression Profiling; Insulin Resistance; Liver; Male; Mice; Mice, Inbred C57BL; Streptozocin; Tea

2022
Epigallocatechin-3-gallate exerts cardioprotective effects related to energy metabolism in pressure overload-induced cardiac dysfunction.
    Archives of biochemistry and biophysics, 2022, 07-15, Volume: 723

    Topics: Animals; Cardiomegaly; Catechin; Disease Models, Animal; Energy Metabolism; Heart Failure; Myocardium; Rats; Reproducibility of Results

2022
Oral antimicrobial peptide-EGCG nanomedicines for synergistic treatment of ulcerative colitis.
    Journal of controlled release : official journal of the Controlled Release Society, 2022, Volume: 347

    Topics: Animals; Antimicrobial Peptides; Catechin; Colitis; Colitis, Ulcerative; Dextran Sulfate; Disease Models, Animal; Inflammation; Lipopolysaccharides; Mice; Nanomedicine; RAW 264.7 Cells

2022
Tea polyphenol epigallocatechin-3-gallate inhibits cell proliferation in a patient-derived triple-negative breast cancer xenograft mouse model via inhibition of proline-dehydrogenase-induced effects.
    Journal of food and drug analysis, 2021, 03-15, Volume: 29, Issue:1

    Topics: Animals; Catechin; Cell Line, Tumor; Cell Proliferation; Disease Models, Animal; Heterografts; Humans; Mice; Polyphenols; Proline; Proline Oxidase; Tea; Triple Negative Breast Neoplasms

2021
Effect of Epigallocatechin-3-gallate on Stress-Induced Depression in a Mouse Model: Role of Interleukin-1β and Brain-Derived Neurotrophic Factor.
    Neurochemical research, 2022, Volume: 47, Issue:11

    Topics: Animals; Antidepressive Agents; Antidepressive Agents, Tricyclic; Antioxidants; Brain-Derived Neurotrophic Factor; Catechin; Clomipramine; Depression; Disease Models, Animal; Hippocampus; Interleukin-1beta; Mice; RNA, Messenger; Stress, Psychological; Tea

2022
HPLC-DAD analysis of Quercus leucotrichophora extract and appraisal of its antiasthmatic potential via modulation of aquaporins, inflammatory, and oxidative stress biomarkers in Albino mice.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2022, Volume: 155

    Topics: Animals; Anti-Asthmatic Agents; Aquaporins; Asthma; Biomarkers; Bronchoalveolar Lavage Fluid; Catalase; Catechin; Chromatography, High Pressure Liquid; Dexamethasone; Disease Models, Animal; Glucuronic Acid; Immunoglobulin E; Interleukin-4; Lung; Malondialdehyde; Mice; Mice, Inbred BALB C; NF-kappa B; Ovalbumin; Oxidative Stress; Quercetin; Quercus; Superoxide Dismutase; Synthetic Drugs; Tumor Necrosis Factor-alpha

2022
(-)-Epicatechin mitigates anxiety-related behavior in a mouse model of high fat diet-induced obesity.
    The Journal of nutritional biochemistry, 2022, Volume: 110

    Topics: Animals; Anxiety; Brain-Derived Neurotrophic Factor; Catechin; Diet, High-Fat; Disease Models, Animal; Male; Mice; Mice, Inbred C57BL; Obesity; RNA, Ribosomal, 16S

2022
Epigallocatechin-3-gallate alleviates galactose-induced aging impairment
    Food & function, 2022, Oct-31, Volume: 13, Issue:21

    Topics: Aging; Animals; Brain; Catechin; Disease Models, Animal; Galactose; Hypothalamo-Hypophyseal System; Mice; Pituitary-Adrenal System; Tea

2022
Green Tea Catechins Modulate Skeletal Development with Effects Dependent on Dose, Time, and Structure in a down Syndrome Mouse Model.
    Nutrients, 2022, Oct-07, Volume: 14, Issue:19

    Topics: Animals; Antioxidants; Catechin; Disease Models, Animal; Down Syndrome; Mice; Plant Extracts; Tea

2022
Bone marrow-targetable Green Tea Catechin-Based Micellar Nanocomplex for synergistic therapy of Acute myeloid leukemia.
    Journal of nanobiotechnology, 2022, Nov-16, Volume: 20, Issue:1

    Topics: Animals; Bone Marrow; Catechin; Disease Models, Animal; Humans; Leukemia, Myeloid, Acute; Mice; Micelles; Sorafenib; Tea; Tissue Distribution

2022
Effect of Alleviating Fibrosis with EGCG-Modified Bone Graft in Murine Model Depended on Less Accumulation of Inflammatory Macrophage.
    BioMed research international, 2023, Volume: 2023

    Topics: Animals; Bone Regeneration; Capsules; Catechin; Disease Models, Animal; Durapatite; Macrophages; Mice; Osteogenesis

2023
EGCG attenuated acute myocardial infarction by inhibiting ferroptosis via miR-450b-5p/ACSL4 axis.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2023, Volume: 119

    Topics: Animals; Catechin; Disease Models, Animal; Mice; MicroRNAs; Myocardial Infarction; Myocardial Ischemia

2023
The identification of cianidanol as a selective estrogen receptor beta agonist and evaluation of its neuroprotective effects on Parkinson's disease models.
    Life sciences, 2023, Nov-15, Volume: 333

    Topics: Animals; Catechin; Disease Models, Animal; Estrogen Receptor beta; Estrogens; Humans; Neuroblastoma; Neuroprotective Agents; Parkinson Disease; Rats; Rotenone

2023
Anti-Ulcerative Colitis Effects and Active Ingredients in Ethyl Acetate Extract from Decoction of
    Molecules (Basel, Switzerland), 2023, Nov-19, Volume: 28, Issue:22

    Topics: Animals; Catechin; Colitis; Colitis, Ulcerative; Colon; Dextran Sulfate; Disease Models, Animal; Mice; Mice, Inbred C57BL; Molecular Docking Simulation; NF-kappa B; NLR Family, Pyrin Domain-Containing 3 Protein; Toll-Like Receptor 4

2023
Cerebral protection of epigallocatechin gallate (EGCG) via preservation of mitochondrial function and ERK inhibition in a rat resuscitation model.
    Drug design, development and therapy, 2019, Volume: 13

    Topics: Animals; Cardiopulmonary Resuscitation; Catechin; Disease Models, Animal; Extracellular Signal-Regulated MAP Kinases; Heart Arrest; Male; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Phosphorylation; Protein Kinase Inhibitors; Rats; Rats, Sprague-Dawley

2019
ERK1/2-HNF4α axis is involved in epigallocatechin-3-gallate inhibition of HBV replication.
    Acta pharmacologica Sinica, 2020, Volume: 41, Issue:2

    Topics: Animals; Antiviral Agents; Catechin; Disease Models, Animal; Dose-Response Relationship, Drug; Gene Expression Regulation, Viral; Hep G2 Cells; Hepatitis B; Hepatitis B virus; Hepatocyte Nuclear Factor 4; Humans; Mice; Mice, Inbred C57BL; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Virus Replication

2020
Flavanol-rich lychee fruit extract substantially reduces progressive cognitive and molecular deficits in a triple-transgenic animal model of Alzheimer disease.
    Nutritional neuroscience, 2021, Volume: 24, Issue:9

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Catechin; Cognitive Dysfunction; Disease Models, Animal; Flavonoids; Fruit; Hippocampus; Humans; Litchi; Male; Mice; Mice, Transgenic; Mutation; Phenols; Phosphorylation; Plant Extracts; tau Proteins; Tea; Transgenes

2021
Green Tea Polyphenol (-)-Epigallocatechin Gallate (EGCG) Attenuates Neuroinflammation in Palmitic Acid-Stimulated BV-2 Microglia and High-Fat Diet-Induced Obese Mice.
    International journal of molecular sciences, 2019, Oct-13, Volume: 20, Issue:20

    Topics: Animals; Anti-Obesity Agents; Catechin; Cell Line; Diet, High-Fat; Disease Models, Animal; Hypothalamus; Inflammation; Interleukin-1beta; Interleukin-6; Janus Kinase 2; Lipid Metabolism; Mice; Mice, Inbred C57BL; Mice, Obese; Microglia; Obesity; Palmitic Acid; Polyphenols; STAT3 Transcription Factor; Tea; Tumor Necrosis Factor-alpha

2019
Epigallocatechin 3-gallate attenuates arthritis by regulating Nrf2, HO-1, and cytokine levels in an experimental arthritis model.
    Biotechnology and applied biochemistry, 2020, Volume: 67, Issue:3

    Topics: Animals; Arthritis, Experimental; Catechin; Collagen Type II; Cytokines; Disease Models, Animal; Female; Heme Oxygenase (Decyclizing); NF-E2-Related Factor 2; Rats; Rats, Wistar

2020
A mouse model of subacute liver failure with ascites induced by step-wise increased doses of (-)-epigallocatechin-3-gallate.
    Scientific reports, 2019, 12-02, Volume: 9, Issue:1

    Topics: Acute Disease; Animals; Antioxidants; Apoptosis; Aquaporin 2; Ascites; Catechin; Disease Models, Animal; Kidney; Liver; Liver Failure; Male; Membrane Transport Proteins; Mice; Urea Transporters

2019
MicroRNA-384-5p/Beclin-1 As Potential Indicators For Epigallocatechin Gallate Against Cardiomyocytes Ischemia Reperfusion Injury By Inhibiting Autophagy Via PI3K/Akt Pathway.
    Drug design, development and therapy, 2019, Volume: 13

    Topics: Animals; Autophagy; Beclin-1; Catechin; Cell Survival; Cells, Cultured; Disease Models, Animal; Dose-Response Relationship, Drug; HEK293 Cells; Humans; MicroRNAs; Molecular Structure; Myocardial Reperfusion Injury; Neuroprotective Agents; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Rats; Structure-Activity Relationship

2019
Protective Effect of (-)Epigallocatechin-3-gallate on Rotenone-Induced Parkinsonism-like Symptoms in Rats.
    Neurotoxicity research, 2020, Volume: 37, Issue:3

    Topics: Animals; Apoptosis; Behavior, Animal; Catechin; Corpus Striatum; Disease Models, Animal; Encephalitis; Inflammation Mediators; Male; Neuroprotective Agents; Parkinsonian Disorders; Rats, Wistar; Rotenone

2020
Protective Effect of Epigallocatechin Gallate in Ischemia-Reperfusion Injury of Rat Skeletal Muscle.
    The Journal of surgical research, 2020, Volume: 247

    Topics: Animals; Antioxidants; Catechin; Cytokines; Disease Models, Animal; Dose-Response Relationship, Drug; Humans; Kidney; Liver; Male; Muscle, Skeletal; Oxidative Stress; Rats; Reactive Oxygen Species; Reperfusion Injury

2020
(-)-Catechin-7-
    Cells, 2019, 12-20, Volume: 9, Issue:1

    Topics: Animals; Catechin; Cell Line; Cell Proliferation; Cell Survival; Disease Models, Animal; Gene Expression Regulation; Hepatic Stellate Cells; Humans; Male; Phosphorylation; Plant Bark; Plant Extracts; Protein Transport; Signal Transduction; STAT3 Transcription Factor; Ulmus

2019
Green tea polyphenols and epigallocatechin-3-gallate protect against perfluorodecanoic acid induced liver damage and inflammation in mice by inhibiting NLRP3 inflammasome activation.
    Food research international (Ottawa, Ont.), 2020, Volume: 127

    Topics: Animals; Antioxidants; Catechin; Decanoic Acids; Disease Models, Animal; Fluorocarbons; Inflammasomes; Inflammation; Liver Diseases; Male; Mice; NLR Family, Pyrin Domain-Containing 3 Protein; Polyphenols; Tea

2020
Effects of (-)-epicatechin on the time course of the expression of perilipins in a diet-induced model of nonalcoholic steatohepatitis.
    The Journal of nutritional biochemistry, 2020, Volume: 77

    Topics: Adiponectin; Animals; Catechin; CD36 Antigens; Cholesterol, LDL; Disease Models, Animal; Fatty Liver; Fructose; Hepatocytes; Liver; Male; Malondialdehyde; Mice; Mice, Inbred C57BL; Non-alcoholic Fatty Liver Disease; Oxidative Stress; Perilipin-2; Perilipin-3; Perilipins; Risk Factors; Triglycerides; Uncoupling Protein 2

2020
Structural Characteristics and Hypolipidemic Activity of Theabrownins from Dark Tea Fermented by Single Species
    Biomolecules, 2020, 01-30, Volume: 10, Issue:2

    Topics: Animals; Aspergillus; Catechin; Disease Models, Animal; Fermentation; Gas Chromatography-Mass Spectrometry; Hyperlipidemias; Molecular Weight; Obesity; Phenol; Plant Extracts; Spectrophotometry, Ultraviolet; Spectroscopy, Fourier Transform Infrared; Tea; X-Ray Diffraction; Zebrafish

2020
(-)-Epigallocatechin-3-gallate provides neuroprotection via AMPK activation against traumatic brain injury in a mouse model.
    Naunyn-Schmiedeberg's archives of pharmacology, 2020, Volume: 393, Issue:11

    Topics: AMP-Activated Protein Kinases; Animals; Behavior, Animal; Brain Injuries, Traumatic; Catechin; Cerebral Cortex; Cognition; Cytokines; Disease Models, Animal; Enzyme Activation; Inflammation Mediators; Male; Mice, Inbred C57BL; Mice, Knockout; Morris Water Maze Test; Motor Activity; Neuroprotective Agents; NF-kappa B; Oxidative Stress; Phosphorylation; Rotarod Performance Test; Signal Transduction

2020
Procyanidin B3 alleviates intervertebral disc degeneration via interaction with the TLR4/MD-2 complex.
    Journal of cellular and molecular medicine, 2020, Volume: 24, Issue:6

    Topics: Animals; Anti-Inflammatory Agents; Biflavonoids; Catechin; Cell Death; Cell Survival; Disease Models, Animal; Disease Progression; Extracellular Matrix; Humans; Intervertebral Disc Degeneration; Lipopolysaccharides; Lymphocyte Antigen 96; Male; Myeloid Differentiation Factor 88; NF-kappa B; Nucleus Pulposus; Proanthocyanidins; Punctures; Rats, Sprague-Dawley; Signal Transduction; TNF Receptor-Associated Factor 6; Toll-Like Receptor 4

2020
EGCG ameliorates neuronal and behavioral defects by remodeling gut microbiota and TotM expression in Drosophila models of Parkinson's disease.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2020, Volume: 34, Issue:4

    Topics: Animals; Behavior, Animal; Catechin; Disease Models, Animal; Drosophila melanogaster; Drosophila Proteins; Female; Gastrointestinal Microbiome; Heat-Shock Proteins; Male; Mitochondria; Neuroprotective Agents; Parkinson Disease

2020
Epigallocatechin-3-gallate Alleviates Cognitive Deficits in APP/PS1 Mice.
    Current medical science, 2020, Volume: 40, Issue:1

    Topics: Administration, Oral; Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Catechin; Cognitive Dysfunction; Cytokines; Disease Models, Animal; Gene Expression Regulation; Humans; Mice; Mice, Transgenic; Mutation; Neuroprotective Agents; Presenilin-1; Treatment Outcome

2020
(-)-Epigallocatechin-3-gallate (EGCG) attenuates salt-induced hypertension and renal injury in Dahl salt-sensitive rats.
    Scientific reports, 2020, 03-16, Volume: 10, Issue:1

    Topics: Acute Kidney Injury; Administration, Oral; Animals; Apoptosis; Catechin; Cells, Cultured; Disease Models, Animal; Fibroblasts; Hypertension; Malondialdehyde; Phytotherapy; Rats; Rats, Inbred Dahl; Receptors, Laminin; Sodium Chloride, Dietary

2020
Epigallocatechin gallate alleviates neuronal cell damage against focal cerebral ischemia in rats.
    The Journal of veterinary medical science, 2020, May-20, Volume: 82, Issue:5

    Topics: Animals; Apoptosis; Brain Ischemia; Caspase 3; Catechin; Cerebral Infarction; Disease Models, Animal; In Situ Nick-End Labeling; Infarction, Middle Cerebral Artery; Male; Neuroprotective Agents; Poly(ADP-ribose) Polymerases; Rats, Sprague-Dawley

2020
Efficacy of Topical Treatment with (-)-Epigallocatechin Gallate, A Green Tea Catechin, in Mice with Cutaneous Leishmaniasis.
    Molecules (Basel, Switzerland), 2020, Apr-10, Volume: 25, Issue:7

    Topics: Animals; Antiprotozoal Agents; Catechin; Disease Models, Animal; Dose-Response Relationship, Drug; Leishmania mexicana; Leishmaniasis, Cutaneous; Mice; Parasitic Sensitivity Tests; Tea

2020
Green tea extract containing enhanced levels of epimerized catechins attenuates scopolamine-induced memory impairment in mice.
    Journal of ethnopharmacology, 2020, Aug-10, Volume: 258

    Topics: Animals; Avoidance Learning; Catechin; Cell Line, Tumor; Disease Models, Animal; DNA Methylation; Dose-Response Relationship, Drug; Hot Temperature; Humans; Male; Maze Learning; Memory Disorders; Mice; Mice, Inbred ICR; Plant Extracts; Scopolamine; Tea

2020
Prefrontal-hippocampal functional connectivity encodes recognition memory and is impaired in intellectual disability.
    Proceedings of the National Academy of Sciences of the United States of America, 2020, 05-26, Volume: 117, Issue:21

    Topics: Animals; Catechin; Disease Models, Animal; Down Syndrome; Executive Function; Female; Hippocampus; Male; Mice; Mice, Inbred C57BL; Nerve Net; Neuroprotective Agents; Prefrontal Cortex; Recognition, Psychology

2020
(-)-Epicatechin mitigates high fat diet-induced neuroinflammation and altered behavior in mice.
    Food & function, 2020, Jun-24, Volume: 11, Issue:6

    Topics: Administration, Oral; Animals; Anti-Inflammatory Agents; Brain Diseases; Catechin; Diet, High-Fat; Disease Models, Animal; Flavonols; Hippocampus; Male; Maze Learning; Memory; Mice; Mice, Inbred C57BL

2020
Theaphenon E prevents fatty liver disease and increases CD4+ T cell survival in mice fed a high-fat diet.
    Clinical nutrition (Edinburgh, Scotland), 2021, Volume: 40, Issue:1

    Topics: Animals; Apoptosis; Catechin; CD4-Positive T-Lymphocytes; Cell Proliferation; Diet, Fat-Restricted; Diet, High-Fat; Disease Models, Animal; Fatty Acids; Hepatocytes; Humans; Linoleic Acid; Lipid Metabolism; Liver; Male; Mice; Mice, Inbred C57BL; Non-alcoholic Fatty Liver Disease; Obesity

2021
Epigallocatechin-3-gallate protects immunity and liver drug-metabolism function in mice loaded with restraint stress.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2020, Volume: 129

    Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Biomarkers; Biotransformation; Catechin; Cytochrome P-450 Enzyme System; Cytokines; Disease Models, Animal; Female; Immunoglobulin A, Secretory; Immunologic Factors; Inflammation Mediators; Isoenzymes; Liver; Male; Mice, Inbred ICR; Oxidative Stress; Restraint, Physical; Stress, Physiological; Stress, Psychological; T-Lymphocyte Subsets

2020
Evaluation of the therapeutic potential of Epigallocatechin-3-gallate (EGCG) via oral gavage in young adult Down syndrome mice.
    Scientific reports, 2020, 06-26, Volume: 10, Issue:1

    Topics: Administration, Oral; Animals; Body Weight; Cancellous Bone; Catechin; Disease Models, Animal; Down Syndrome; Femur; Maze Learning; Mice; Treatment Outcome; X-Ray Microtomography

2020
Long-acting mucoadhesive thermogels for improving topical treatments of dry eye disease.
    Materials science & engineering. C, Materials for biological applications, 2020, Volume: 115

    Topics: Acrylic Resins; Administration, Topical; Animals; Apoptosis; Catechin; Cell Line; Delayed-Action Preparations; Disease Models, Animal; Drug Carriers; Dry Eye Syndromes; Female; Gelatin; Humans; Lectins; Ophthalmic Solutions; Oxidative Stress; Rabbits

2020
Brain-targeted co-delivery of β-amyloid converting enzyme 1 shRNA and epigallocatechin-3-gallate by multifunctional nanocarriers for Alzheimer's disease treatment.
    IUBMB life, 2020, Volume: 72, Issue:8

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid Precursor Protein Secretases; Animals; Aspartic Acid Endopeptidases; Blood-Brain Barrier; Brain; Catechin; Disease Models, Animal; Humans; Mice; Mice, Transgenic; RNA, Small Interfering

2020
Procyanidin B2 Improves Oocyte Maturation and Subsequent Development in Type 1 Diabetic Mice by Promoting Mitochondrial Function.
    Reproductive sciences (Thousand Oaks, Calif.), 2020, Volume: 27, Issue:12

    Topics: Animals; Biflavonoids; Catechin; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Disease Models, Animal; Female; Membrane Potential, Mitochondrial; Mice, Inbred ICR; Mitochondria; Oocytes; Oxidative Stress; Proanthocyanidins; Reactive Oxygen Species; Streptozocin

2020
Protection of procyanidin B2 on mitochondrial dynamics in sepsis associated acute kidney injury via promoting Nrf2 nuclear translocation.
    Aging, 2020, 08-15, Volume: 12, Issue:15

    Topics: Active Transport, Cell Nucleus; Acute Kidney Injury; Animals; Antioxidants; Apoptosis; Biflavonoids; Catechin; Disease Models, Animal; Kidney; Male; Mice, Inbred C57BL; Mitochondria; Mitochondrial Dynamics; Mitophagy; NF-E2-Related Factor 2; Oxidative Stress; Proanthocyanidins; Sepsis

2020
Effects of EGCG on depression-related behavior and serotonin concentration in a rat model of chronic unpredictable mild stress.
    Food & function, 2020, Oct-21, Volume: 11, Issue:10

    Topics: Animals; Antidepressive Agents; Behavior, Animal; Brain; Catechin; Colon; Depression; Disease Models, Animal; Hippocampus; Male; Open Field Test; Rats; Rats, Wistar; Serotonin; Stress, Psychological; Swimming

2020
Chaetomium globosum extract mediated gold nanoparticle synthesis and potent anti-inflammatory activity.
    Analytical biochemistry, 2021, 01-01, Volume: 612

    Topics: Acetic Acid; Animals; Anti-Inflammatory Agents; Behavior, Animal; Carrageenan; Catechin; Chaetomium; Cyclooxygenase 2; Disease Models, Animal; Edema; Endophytes; Female; Gold; HeLa Cells; Humans; Hydrogen-Ion Concentration; Inflammation; Lipoxygenase; Male; Metal Nanoparticles; Mice; Plant Leaves; Vitex; Xanthine Oxidase

2021
Re-establishment of the epigenetic state and rescue of kinome deregulation in Ts65Dn mice upon treatment with green tea extract and environmental enrichment.
    Scientific reports, 2020, 09-29, Volume: 10, Issue:1

    Topics: Animals; Camellia sinensis; Catechin; Chromatography, Liquid; Cognition; Disease Models, Animal; Down Syndrome; Epigenesis, Genetic; Hippocampus; Mice; Mice, Transgenic; Phosphorylation; Plant Extracts; Protein Interaction Maps; Proteomics; Tandem Mass Spectrometry

2020
Epigallocatechin gallate induces chemopreventive effects on rats with diethylnitrosamine‑induced liver cancer via inhibition of cell division cycle 25A.
    Molecular medicine reports, 2020, Volume: 22, Issue:5

    Topics: Animals; Antineoplastic Agents, Phytogenic; Carcinoma, Hepatocellular; Catechin; cdc25 Phosphatases; Cell Cycle; Cell Proliferation; Cell Survival; Diethylnitrosamine; Disease Models, Animal; Hep G2 Cells; Humans; Liver; Liver Neoplasms; Male; Phytotherapy; Plant Extracts; Rats; Rats, Sprague-Dawley; Tea; Transfection; Tumor Burden

2020
Epigallocatechin-3-Gallate Reduces Visceral Adiposity Partly through the Regulation of Beclin1-Dependent Autophagy in White Adipose Tissues.
    Nutrients, 2020, Oct-08, Volume: 12, Issue:10

    Topics: Adipose Tissue, White; Adiposity; Animals; Autophagy; Beclin-1; Catechin; Diet, High-Fat; Disease Models, Animal; Gene Expression Regulation, Developmental; Intra-Abdominal Fat; Male; Mice; Mice, Inbred C57BL; Obesity

2020
(-)-Epicatechin reduces muscle waste after complete spinal cord transection in a murine model: role of ubiquitin-proteasome system.
    Molecular biology reports, 2020, Volume: 47, Issue:11

    Topics: Animals; Catechin; Disease Models, Animal; Female; Magnetic Resonance Imaging; Muscle, Skeletal; Muscular Atrophy; Myofibrils; Proteasome Endopeptidase Complex; Rats, Long-Evans; Spinal Cord Injuries

2020
Tissue distribution and molecular docking research on the active components of Bidens bipinnata L. against hyperlipidemia.
    Biomedical chromatography : BMC, 2021, Volume: 35, Issue:4

    Topics: Animals; Bidens; Catechin; Chromatography, High Pressure Liquid; Disease Models, Animal; Drugs, Chinese Herbal; Gallic Acid; Hyperlipidemias; Linear Models; Liver; Molecular Docking Simulation; Rats; Reproducibility of Results; Rutin; Sensitivity and Specificity; Tandem Mass Spectrometry; Tissue Distribution

2021
Anti-Melanogenesis Effects of Lotus Seedpod In Vitro and In Vivo.
    Nutrients, 2020, Nov-18, Volume: 12, Issue:11

    Topics: Animals; Catechin; Disease Models, Animal; Lotus; Melanins; Mice; Mice, Inbred C57BL; Pigmentation Disorders; Plant Extracts; Seeds; Signal Transduction

2020
Theaflavin ameliorates renal ischemia/reperfusion injury by activating the Nrf2 signalling pathway in vivo and in vitro.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2021, Volume: 134

    Topics: Animals; Antioxidants; Apoptosis; Biflavonoids; Catechin; Cell Survival; Disease Models, Animal; Heme Oxygenase-1; Kidney; Kidney Diseases; Male; Malondialdehyde; Mice; Mice, Inbred C57BL; Mitochondria; NF-E2-Related Factor 2; Oxidative Stress; Reperfusion Injury; Signal Transduction; Up-Regulation

2021
Epigallocatechin-3-gallate reduces liver and immune system damage in Acinetobacter baumannii-loaded mice with restraint stress.
    International immunopharmacology, 2021, Volume: 92

    Topics: Acinetobacter baumannii; Acinetobacter Infections; Animals; Antioxidants; Catechin; Disease Models, Animal; Female; Immune System; Inflammation; Liver Diseases; Male; Mice; Mice, Inbred ICR; Oxidative Stress

2021
Modulators of Neuroinflammation Have a Beneficial Effect in a Lafora Disease Mouse Model.
    Molecular neurobiology, 2021, Volume: 58, Issue:6

    Topics: Animals; Biomarkers; Brain; Catechin; Disease Models, Animal; Gliosis; Glucans; Hippocampus; Inclusion Bodies; Inflammation; Lafora Disease; Mice, Inbred C57BL; Mice, Knockout; Microglia; Motor Activity; Nerve Degeneration; Neurons; Phenotype; Propranolol; Ubiquitin-Protein Ligases

2021
Epigallocatechin Gallate Ameliorates the Effects of Prenatal Alcohol Exposure in a Fetal Alcohol Spectrum Disorder-Like Mouse Model.
    International journal of molecular sciences, 2021, Jan-13, Volume: 22, Issue:2

    Topics: Animals; Astrocytes; Biomarkers; Catechin; Cell Differentiation; Disease Models, Animal; Doublecortin Protein; Ethanol; Female; Fetal Alcohol Spectrum Disorders; Immunohistochemistry; Male; Maternal Exposure; Mice; Neurogenesis; Neurons; Oxidative Stress; Placenta; Pregnancy; Prenatal Exposure Delayed Effects

2021
Theaflavin protects chondrocytes against apoptosis and senescence
    Food & function, 2021, Mar-01, Volume: 12, Issue:4

    Topics: Animals; Apoptosis; Biflavonoids; Catechin; Cells, Cultured; Cellular Senescence; Chondrocytes; Disease Models, Animal; Female; Humans; Mice; Mice, Inbred C57BL; NF-E2-Related Factor 2; Osteoarthritis; Protective Agents

2021
Epigallocatechin-3-gallate prevents inflammation and diabetes -Induced glucose tolerance through inhibition of NLRP3 inflammasome activation.
    International immunopharmacology, 2021, Volume: 93

    Topics: Animals; Anti-Inflammatory Agents; Bone Marrow; Catechin; Cells, Cultured; Diabetes Mellitus, Type 2; Diet, High-Fat; Disease Models, Animal; Glucose Tolerance Test; Humans; Inflammasomes; Inflammation; Macrophages; Mice; Mice, Inbred C57BL; NLR Family, Pyrin Domain-Containing 3 Protein; Pyroptosis

2021
Green tea extracts containing epigallocatechin-3-gallate modulate facial development in Down syndrome.
    Scientific reports, 2021, 02-25, Volume: 11, Issue:1

    Topics: Adolescent; Animals; Catechin; Child; Child, Preschool; Dietary Supplements; Disease Models, Animal; Down Syndrome; Face; Female; Humans; Infant; Male; Mice; Plant Extracts; Tea

2021
Epigallocatechin-3-Gallate Dampens Non-Alcoholic Fatty Liver by Modulating Liver Function, Lipid Profile and Macrophage Polarization.
    Nutrients, 2021, Feb-11, Volume: 13, Issue:2

    Topics: Adipose Tissue; Animals; Body Weight; Catechin; Cholesterol; Diet, High-Fat; Disease Models, Animal; Lipids; Liver; Macrophages; Male; Mice; Mice, Inbred C57BL; Non-alcoholic Fatty Liver Disease; Organ Size

2021
Amelioration of N,N'-dimethylhydrazine induced colon toxicity by epigallocatechin gallate in Wistar rats.
    Human & experimental toxicology, 2021, Volume: 40, Issue:9

    Topics: 1,2-Dimethylhydrazine; Animals; Anticarcinogenic Agents; Carcinogens; Catechin; Colonic Neoplasms; Disease Models, Animal; Humans; Male; Rats; Rats, Wistar

2021
(-)-Epicatechin protects from amebic liver abscess development in hamster.
    Experimental parasitology, 2021, Volume: 224

    Topics: Analysis of Variance; Animals; Antiprotozoal Agents; Catechin; Cricetinae; Cytokines; Dimethyl Sulfoxide; Disease Models, Animal; Liver; Liver Abscess, Amebic; Male; Mesocricetus; Metronidazole; Real-Time Polymerase Chain Reaction

2021
Identification of regulated proteins by epigallocatechin gallate treatment in an ischemic cerebral cortex animal model: a proteomics approach.
    The Journal of veterinary medical science, 2021, Jun-09, Volume: 83, Issue:6

    Topics: Animals; Catechin; Cerebral Cortex; Disease Models, Animal; Infarction, Middle Cerebral Artery; Proteomics; Rats; Rats, Sprague-Dawley; Rodent Diseases

2021
Epigallocatechin-3-Gallate Alleviates High-Fat Diet-Induced Nonalcoholic Fatty Liver Disease via Inhibition of Apoptosis and Promotion of Autophagy through the ROS/MAPK Signaling Pathway.
    Oxidative medicine and cellular longevity, 2021, Volume: 2021

    Topics: Animals; Apoptosis; Autophagy; Catechin; Diet, High-Fat; Disease Models, Animal; Disease Progression; Humans; Male; Mice; Mitogen-Activated Protein Kinases; Non-alcoholic Fatty Liver Disease; Signal Transduction

2021
Natural antioxidants enhance the power of physical and mental activities versus risk factors inducing progression of Alzheimer's disease in rats.
    International immunopharmacology, 2021, Volume: 96

    Topics: Alzheimer Disease; Animals; Antioxidants; Ascorbic Acid; Catechin; Disease Models, Animal; Disease Progression; Male; Mental Health; Physical Conditioning, Animal; Rats; Rats, Sprague-Dawley; Risk Factors; Selenium; Vitamin E

2021
Epigallocatechin-3-gallate attenuates acute pancreatitis induced lung injury by targeting mitochondrial reactive oxygen species triggered NLRP3 inflammasome activation.
    Food & function, 2021, Jun-21, Volume: 12, Issue:12

    Topics: Acute Lung Injury; Animals; Antioxidants; Catechin; Disease Models, Animal; DNA, Mitochondrial; Inflammasomes; Inflammation; Lung; Lung Injury; Male; Mice; Mitochondria; NLR Family, Pyrin Domain-Containing 3 Protein; Pancreatitis; Reactive Oxygen Species; Tea

2021
First morphological-level insights into the efficiency of green tea catechins and grape seed procyanidins on a transgenic mouse model of celiac disease enteropathy.
    Food & function, 2021, Jul-05, Volume: 12, Issue:13

    Topics: Animals; Antioxidants; Biflavonoids; Catechin; Celiac Disease; Disease Models, Animal; Gliadin; Intestinal Diseases; Intestinal Mucosa; Male; Mice; Mice, Transgenic; Proanthocyanidins; Seeds; Tea; Vitis

2021
Epicatechin treatment generates resilience to chronic mild stress-induced depression in a murine model.
    Physiology & behavior, 2021, 09-01, Volume: 238

    Topics: Animals; Anxiety; Catechin; Depression; Depressive Disorder; Disease Models, Animal; Male; Mice; Stress, Psychological

2021
Procyanidin B2 alleviates liver injury caused by cold stimulation through Sonic hedgehog signalling and autophagy.
    Journal of cellular and molecular medicine, 2021, Volume: 25, Issue:16

    Topics: Animals; Autophagy; Biflavonoids; Catechin; Cold Temperature; Disease Models, Animal; Hedgehog Proteins; Liver; Male; Mice; Mice, Inbred C57BL; NF-E2-Related Factor 2; Oxidative Stress; Proanthocyanidins; Signal Transduction

2021
[Constructing Brain Aβ-Targeting Nanoparticles Loaded with EGCG for Treating Alzheimer's Disease in Mice].
    Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition, 2021, Volume: 52, Issue:4

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Brain; Catechin; Disease Models, Animal; Hippocampus; Mice; Mice, Inbred ICR; Nanoparticles; Oligopeptides

2021
(-)-Epicatechin ameliorates cigarette smoke-induced lung inflammation via inhibiting ROS/NLRP3 inflammasome pathway in rats with COPD.
    Toxicology and applied pharmacology, 2021, 10-15, Volume: 429

    Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Catechin; Cell Line; Disease Models, Animal; Epithelial Cells; Humans; Inflammasomes; Kelch-Like ECH-Associated Protein 1; Lung; Male; NF-E2-Related Factor 2; NLR Family, Pyrin Domain-Containing 3 Protein; Oxidative Stress; Pneumonia; Proteolysis; Pulmonary Disease, Chronic Obstructive; Pyroptosis; Rats, Wistar; Reactive Oxygen Species; Signal Transduction; Smoke; Tobacco Products; Transcription Factors; Tripartite Motif Proteins; Ubiquitin-Protein Ligases

2021
Therapeutic Efficacy of Nanocomplex of Poly(Ethylene Glycol) and Catechin for Dry Eye Disease in a Mouse Model.
    Investigative ophthalmology & visual science, 2017, 03-01, Volume: 58, Issue:3

    Topics: Animals; Catechin; Conjunctiva; Cornea; Disease Models, Animal; Drug Therapy, Combination; Dry Eye Syndromes; Lacrimal Apparatus; Mice; Mice, Inbred NOD; Nanoparticles; Ophthalmic Solutions; Polyethylene Glycols; Surface-Active Agents; Tears; Treatment Outcome

2017
Epigallocatechin gallate upregulates NRF2 to prevent diabetic nephropathy via disabling KEAP1.
    Free radical biology & medicine, 2017, Volume: 108

    Topics: Animals; Catechin; Cells, Cultured; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Disease Models, Animal; Inflammation; Kelch-Like ECH-Associated Protein 1; Kidney; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; NF-E2-Related Factor 2; Oxidative Stress; RNA, Small Interfering; Signal Transduction; Up-Regulation

2017
Epigallocatechin-3-gallate (EGCG) consumption in the Ts65Dn model of Down syndrome fails to improve behavioral deficits and is detrimental to skeletal phenotypes.
    Physiology & behavior, 2017, Aug-01, Volume: 177

    Topics: Administration, Oral; Animals; Brain; Catechin; Cognition; Disease Models, Animal; Down Syndrome; Dyrk Kinases; Femur; Male; Maze Learning; Mice, Inbred C3H; Mice, Transgenic; Motor Activity; Phenotype; Protease Inhibitors; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Random Allocation; Recognition, Psychology; Treatment Failure

2017
PDE3 inhibitor and EGCG combination treatment suppress cancer stem cell properties in pancreatic ductal adenocarcinoma.
    Scientific reports, 2017, 05-15, Volume: 7, Issue:1

    Topics: Animals; Biomarkers, Tumor; Carcinoma, Pancreatic Ductal; Catechin; Cell Line, Tumor; Cyclic GMP; Cyclic Nucleotide Phosphodiesterases, Type 3; Disease Models, Animal; Drug Synergism; Fluorescent Antibody Technique; Gene Expression; Humans; Mice; Neoplastic Stem Cells; Phosphodiesterase 3 Inhibitors; Xenograft Model Antitumor Assays

2017
(-)-Epigallocatechin-3-gallate ameliorates memory impairment and rescues the abnormal synaptic protein levels in the frontal cortex and hippocampus in a mouse model of Alzheimer's disease.
    Neuroreport, 2017, Jul-05, Volume: 28, Issue:10

    Topics: Administration, Oral; Alzheimer Disease; Amyloid beta-Peptides; Amyloid Precursor Protein Secretases; Animals; Aspartic Acid Endopeptidases; Catechin; Disease Models, Animal; Disks Large Homolog 4 Protein; Frontal Lobe; Hippocampus; Maze Learning; Memory Disorders; Mice; Motor Activity; Neuroprotective Agents; Nootropic Agents; Peptide Fragments; Phosphorylation; Random Allocation; Spatial Memory; Synaptophysin; tau Proteins

2017
Anti-inflammatory effect of epigallocatechin gallate in a mouse model of ovalbumin-induced allergic rhinitis.
    International immunopharmacology, 2017, Volume: 49

    Topics: Allergens; Animals; Anti-Inflammatory Agents; Catechin; Cyclooxygenase 2; Cytokines; Disease Models, Animal; Female; Histamine; Humans; Immunoglobulin E; Inflammation Mediators; Mice; Mice, Inbred BALB C; Ovalbumin; Rhinitis, Allergic; Sneezing; Tea

2017
Epigallocatechin-3-gallate and related phenol compounds redirect the amyloidogenic aggregation pathway of ataxin-3 towards non-toxic aggregates and prevent toxicity in neural cells and Caenorhabditis elegans animal model.
    Human molecular genetics, 2017, 09-01, Volume: 26, Issue:17

    Topics: Amyloid; Amyloidogenic Proteins; Animals; Ataxin-3; Caenorhabditis elegans; Catechin; Disease Models, Animal; Humans; Hydrogen Bonding; Molecular Docking Simulation; Nerve Tissue Proteins; Neurodegenerative Diseases; Neurons; Nuclear Proteins; Peptides; Phenols

2017
Green tea polyphenols ameliorate non-alcoholic fatty liver disease through upregulating AMPK activation in high fat fed Zucker fatty rats.
    World journal of gastroenterology, 2017, Jun-07, Volume: 23, Issue:21

    Topics: Acetyl-CoA Carboxylase; AMP-Activated Protein Kinases; Animals; Antioxidants; Catechin; Diet, High-Fat; Disease Models, Animal; Humans; Lipid Metabolism; Lipogenesis; Liver; Liver Function Tests; Male; Non-alcoholic Fatty Liver Disease; Phosphorylation; Polyphenols; Rats; Rats, Zucker; Signal Transduction; Sterol Regulatory Element Binding Protein 1; Tea; Transcriptional Activation; Triglycerides; Up-Regulation; Weight Gain

2017
Catechin attenuates traumatic brain injury-induced blood-brain barrier damage and improves longer-term neurological outcomes in rats.
    Experimental physiology, 2017, 10-01, Volume: 102, Issue:10

    Topics: Animals; Blood-Brain Barrier; Brain Injuries, Traumatic; Catechin; Disease Models, Animal; Inflammation; Male; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Zonula Occludens-1 Protein

2017
Identification of Circulating miR-125b as a Potential Biomarker of Alzheimer's Disease in APP/PS1 Transgenic Mouse.
    Journal of Alzheimer's disease : JAD, 2017, Volume: 59, Issue:4

    Topics: Alzheimer Disease; Amyloid beta-Protein Precursor; Analysis of Variance; Animals; Biomarkers; Catechin; Cell Line, Tumor; Cognition Disorders; Disease Models, Animal; Gene Expression Regulation; Humans; Maze Learning; Mice; Mice, Inbred C57BL; Mice, Transgenic; MicroRNAs; Mutation; Neuroblastoma; Presenilin-1; Protease Inhibitors; RNA, Messenger

2017
Astilbe thunbergii reduces postprandial hyperglycemia in a type 2 diabetes rat model via pancreatic alpha-amylase inhibition by highly condensed procyanidins.
    Bioscience, biotechnology, and biochemistry, 2017, Volume: 81, Issue:9

    Topics: Animals; Biflavonoids; Catechin; Diabetes Mellitus, Type 2; Disease Models, Animal; Glucagon-Like Peptide-1 Receptor; Glycoside Hydrolase Inhibitors; Hyperglycemia; Male; Proanthocyanidins; Rats; Saxifragaceae

2017
Possible role of antioxidative capacity of (-)-epigallocatechin-3-gallate treatment in morphological and neurobehavioral recovery after sciatic nerve crush injury.
    Journal of neurosurgery. Spine, 2017, Volume: 27, Issue:5

    Topics: Animals; Antioxidants; Axons; Catechin; Crush Injuries; Disease Models, Animal; Hyperalgesia; Male; Motor Activity; Nerve Regeneration; Neuroprotective Agents; Oxidative Stress; Peripheral Nerve Injuries; Random Allocation; Rats, Wistar; Recovery of Function; RNA, Messenger; Sciatic Nerve; Sciatic Neuropathy; Spinal Cord

2017
Dextran-Catechin inhibits angiogenesis by disrupting copper homeostasis in endothelial cells.
    Scientific reports, 2017, 08-09, Volume: 7, Issue:1

    Topics: Animals; Antineoplastic Agents; Catechin; Cation Transport Proteins; Cell Survival; Cells, Cultured; Copper; Copper Transport Proteins; Copper Transporter 1; Dextrans; Disease Models, Animal; Endothelial Cells; Heterografts; Homeostasis; Humans; Metallochaperones; Molecular Chaperones; Neoplasm Transplantation; Neovascularization, Pathologic; Neuroblastoma; Reactive Oxygen Species; Trace Elements; Treatment Outcome

2017
(-)-Epigallocatechin-3-gallate and atorvastatin treatment down-regulates liver fibrosis-related genes in non-alcoholic fatty liver disease.
    Clinical and experimental pharmacology & physiology, 2017, Volume: 44, Issue:12

    Topics: Animals; Atorvastatin; Catechin; Disease Models, Animal; Down-Regulation; Fibrillar Collagens; Gene Expression; Humans; Liver Cirrhosis; Male; Mice, Inbred C57BL; Multigene Family; Non-alcoholic Fatty Liver Disease

2017
Combinatorial bioactive botanicals re-sensitize tamoxifen treatment in ER-negative breast cancer via epigenetic reactivation of ERα expression.
    Scientific reports, 2017, 08-24, Volume: 7, Issue:1

    Topics: Animals; Antineoplastic Agents, Hormonal; Breast Neoplasms; Catechin; Cell Line, Tumor; Disease Models, Animal; Drug Resistance; Drug Synergism; Drug Therapy, Combination; Epigenesis, Genetic; Estrogen Receptor alpha; Heterografts; Humans; Isothiocyanates; Mice; Neoplasm Transplantation; Phytochemicals; Sulfoxides; Tamoxifen; Treatment Outcome

2017
Green tea supplementation produces better neuroprotective effects than red and black tea in Alzheimer-like rat model.
    Food research international (Ottawa, Ont.), 2017, Volume: 100, Issue:Pt 1

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Behavior, Animal; Body Weight; Catechin; Disease Models, Animal; Hippocampus; Male; Memory; Neuroprotective Agents; Oxidative Stress; Rats; Rats, Wistar; Tea

2017
Oligonol, a Low-Molecular Weight Polyphenol Derived from Lychee, Alleviates Muscle Loss in Diabetes by Suppressing Atrogin-1 and MuRF1.
    Nutrients, 2017, Sep-20, Volume: 9, Issue:9

    Topics: Animals; Catechin; Cell Differentiation; Cells, Cultured; Diabetes Mellitus, Experimental; Disease Models, Animal; Forkhead Box Protein O3; Fruit; Gene Expression Regulation; Litchi; Male; Mice; Mice, Inbred C57BL; Molecular Weight; Muscle Proteins; Muscle, Skeletal; NF-kappa B; Phenols; Polyphenols; RNA, Messenger; Sarcopenia; Sirtuin 1; SKP Cullin F-Box Protein Ligases; Tripartite Motif Proteins; Ubiquitin-Protein Ligases

2017
Effects of green tea epigallocatechin-3-gallate on the proteolipid protein and oligodendrocyte transcription factor 1 messenger RNA gene expression in a mouse model of multiple sclerosis.
    Folia neuropathologica, 2017, Volume: 55, Issue:3

    Topics: Animals; Basic Helix-Loop-Helix Transcription Factors; Brain; Catechin; Cuprizone; Demyelinating Diseases; Disease Models, Animal; Mice, Inbred C57BL; Multiple Sclerosis; Oligodendroglia; RNA, Messenger; Tea

2017
Anti-oxidants correct disturbance of redox enzymes in the hearts of rat fetuses with congenital diaphragmatic hernia.
    Pediatric surgery international, 2018, Volume: 34, Issue:3

    Topics: Acetophenones; Animals; Antioxidants; Catalase; Catechin; Disease Models, Animal; Female; Glutathione Peroxidase; Glutathione Peroxidase GPX1; Hernias, Diaphragmatic, Congenital; Hydrogen Peroxide; Myocardium; NADPH Oxidase 1; NADPH Oxidase 2; NADPH Oxidase 4; Pregnancy; Rats; Rats, Sprague-Dawley; RNA, Messenger; Superoxide Dismutase

2018
The cardioprotective effects of (-)-Epicatechin are mediated through arginase activity inhibition in a murine model of ischemia/reperfusion.
    European journal of pharmacology, 2018, Jan-05, Volume: 818

    Topics: Animals; Arginase; Cardiotonic Agents; Catechin; Disease Models, Animal; Enzyme Inhibitors; Molecular Docking Simulation; Myocardium; Nitric Oxide Synthase; Protein Conformation; Reperfusion Injury

2018
Protective effect of catechin on humoral and cell mediated immunity in rat model.
    International immunopharmacology, 2018, Volume: 54

    Topics: Animals; Carbon; Catechin; Cattle; Disease Models, Animal; Erythrocytes; Female; Humans; Hypersensitivity, Delayed; Immunity, Cellular; Immunity, Humoral; Immunomodulation; Male; Rats; Rats, Wistar

2018
Epigallocatechin-3-gallate inhibits inflammation and epithelial‑mesenchymal transition through the PI3K/AKT pathway via upregulation of PTEN in asthma.
    International journal of molecular medicine, 2018, Volume: 41, Issue:2

    Topics: Airway Remodeling; Animals; Asthma; Catechin; Disease Models, Animal; Epithelial-Mesenchymal Transition; Humans; Inflammation; Mice; Oncogene Protein v-akt; Ovalbumin; Phosphatidylinositol 3-Kinases; PTEN Phosphohydrolase; Signal Transduction; Tea

2018
EGCG-mediated Protection of the Membrane Disruption and Cytotoxicity Caused by the 'Active Oligomer' of α-Synuclein.
    Scientific reports, 2017, 12-20, Volume: 7, Issue:1

    Topics: alpha-Synuclein; Amyloid; Animals; Catechin; Cell Membrane; Disease Models, Animal; Drosophila melanogaster; Electrophoresis, Polyacrylamide Gel; Microscopy, Electron, Transmission; Parkinson Disease

2017
Effects of (-)-epigallocatechin-3-gallate on EGFR- or Fusion Gene-driven Lung Cancer Cells.
    Acta medica Okayama, 2017, Volume: 71, Issue:6

    Topics: Anaplastic Lymphoma Kinase; Animals; Blood Proteins; Blotting, Western; Carcinoma, Non-Small-Cell Lung; Catechin; Cell Line, Tumor; Crizotinib; Disease Models, Animal; ErbB Receptors; Female; Gene Rearrangement; Heterografts; Humans; Lung Neoplasms; Mice; Mice, Inbred BALB C; Mice, Nude; Mutation; Oncogene Proteins, Fusion; Polyphenols; Protein S; Protein-Tyrosine Kinases; Pyrazoles; Pyridines; Receptor Protein-Tyrosine Kinases; Tea

2017
Structural shift of gut microbiota during chemo-preventive effects of epigallocatechin gallate on colorectal carcinogenesis in mice.
    World journal of gastroenterology, 2017, Dec-14, Volume: 23, Issue:46

    Topics: Aberrant Crypt Foci; Animals; Anticarcinogenic Agents; Azoxymethane; Carcinogenesis; Carcinogens; Catechin; Colon; Colorectal Neoplasms; Dextran Sulfate; Disease Models, Animal; Female; Gastrointestinal Microbiome; Humans; Mice; Rectum; RNA, Ribosomal, 16S

2017
The evaluation of the quality of Feng Huang Oolong teas and their modulatory effect on intestinal microbiota of high-fat diet-induced obesity mice model.
    International journal of food sciences and nutrition, 2018, Volume: 69, Issue:7

    Topics: Adult; Altitude; Amino Acids; Animals; Catechin; Diet, High-Fat; Disease Models, Animal; Female; Gastrointestinal Microbiome; Humans; Male; Mice; Mice, Inbred C57BL; Obesity; Polyphenols; Tea

2018
Liposomal TriCurin, A Synergistic Combination of Curcumin, Epicatechin Gallate and Resveratrol, Repolarizes Tumor-Associated Microglia/Macrophages, and Eliminates Glioblastoma (GBM) and GBM Stem Cells.
    Molecules (Basel, Switzerland), 2018, Jan-18, Volume: 23, Issue:1

    Topics: Animals; Biomarkers, Tumor; Catechin; Cell Line, Tumor; Curcumin; Disease Models, Animal; Drug Combinations; Drug Synergism; Glioblastoma; Humans; Immunophenotyping; Killer Cells, Natural; Liposomes; Lymphocytes, Tumor-Infiltrating; Macrophages; Mice; Microglia; Neoplastic Stem Cells; Resveratrol; Stilbenes; Tumor Suppressor Protein p53; Xenograft Model Antitumor Assays

2018
(-)-Epigallocatechin-3-gallate modulates peripheral immunity in the MPTP-induced mouse model of Parkinson's disease.
    Molecular medicine reports, 2018, Volume: 17, Issue:4

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Catechin; Disease Models, Animal; Dopaminergic Neurons; Immunomodulation; Male; Mice; Neuroprotective Agents; Parkinson Disease; T-Lymphocyte Subsets; Tyrosine 3-Monooxygenase

2018
Phytochemical analysis and antibacterial activity of methanolic extract of Bergenia purpurascens against common respiratory infection causing bacterial species in vitro and in neonatal rats.
    Microbial pathogenesis, 2018, Volume: 117

    Topics: Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents; Antioxidants; Bacteria; Benzopyrans; Catechin; Disease Models, Animal; Drugs, Chinese Herbal; Flavanones; Gallic Acid; Methanol; Microbial Sensitivity Tests; Phytochemicals; Plant Extracts; Plant Leaves; Rats; Respiratory Tract Infections; Saxifragaceae; Staphylococcal Infections; Staphylococcus aureus

2018
EGCG Maintains Th1/Th2 Balance and Mitigates Ulcerative Colitis Induced by Dextran Sulfate Sodium through TLR4/MyD88/NF-
    Canadian journal of gastroenterology & hepatology, 2017, Volume: 2017

    Topics: Animals; Catechin; Colitis, Ulcerative; Dextran Sulfate; Disease Models, Animal; Intestinal Mucosa; Intestines; Male; Myeloid Differentiation Factor 88; Neuroprotective Agents; NF-kappa B; Rats; Rats, Sprague-Dawley; Signal Transduction; Spleen; Th1-Th2 Balance; Toll-Like Receptor 4

2017
Ameliorative Effect of Epigallocatechin Gallate on Cardiac Hypertrophy and Fibrosis in Aged Rats.
    Journal of cardiovascular pharmacology, 2018, Volume: 71, Issue:2

    Topics: Age Factors; Aging; Animals; Antioxidants; Apoptosis; Cardiomyopathies; Catechin; Disease Models, Animal; Fibrosis; Hypertrophy, Left Ventricular; Lipids; Myocytes, Cardiac; Oxidative Stress; Rats, Wistar; Reactive Oxygen Species; Signal Transduction; Ventricular Function, Left; Ventricular Remodeling

2018
Effects of procyanidin on cardiomyocyte apoptosis after myocardial ischemia reperfusion in rats.
    BMC cardiovascular disorders, 2018, 02-13, Volume: 18, Issue:1

    Topics: Animals; Apoptosis; Apoptosis Regulatory Proteins; Biflavonoids; Catechin; Creatine Kinase, MB Form; Cytoprotection; Disease Models, Animal; Male; Myocardial Reperfusion Injury; Myocytes, Cardiac; Oxidative Stress; Proanthocyanidins; Rats, Sprague-Dawley; Reactive Oxygen Species; Signal Transduction

2018
Catechin Attenuates Coronary Heart Disease in a Rat Model by Inhibiting Inflammation.
    Cardiovascular toxicology, 2018, Volume: 18, Issue:5

    Topics: Animals; Anti-Inflammatory Agents; Biomarkers; Blood Glucose; Cardiovascular Agents; Catechin; Coronary Disease; Cytokines; Disease Models, Animal; Inflammation Mediators; Lipids; Myocytes, Cardiac; Rats, Wistar; Signal Transduction; Stroke Volume; Ventricular Function, Left

2018
SOX2OT variant 7 contributes to the synergistic interaction between EGCG and Doxorubicin to kill osteosarcoma via autophagy and stemness inhibition.
    Journal of experimental & clinical cancer research : CR, 2018, Feb-23, Volume: 37, Issue:1

    Topics: Animals; Apoptosis; Autophagy; Biomarkers; Bone Neoplasms; Catechin; Cell Line, Tumor; Cell Proliferation; Cell Self Renewal; Disease Models, Animal; Doxorubicin; Gene Expression; Humans; Intracellular Signaling Peptides and Proteins; Male; Membrane Proteins; Mice; Neoplastic Stem Cells; Osteosarcoma; Receptor, Notch3; RNA, Long Noncoding; Xenograft Model Antitumor Assays

2018
Epigallocatechin-3-gallate improves cardiac hypertrophy and short-term memory deficits in a Williams-Beuren syndrome mouse model.
    PloS one, 2018, Volume: 13, Issue:3

    Topics: Animals; Cardiomegaly; Catechin; Disease Models, Animal; Memory Disorders; Memory, Short-Term; Mice; Mice, Mutant Strains; Williams Syndrome

2018
Epigallocatechin-3-gallate alleviates bladder overactivity in a rat model with metabolic syndrome and ovarian hormone deficiency through mitochondria apoptosis pathways.
    Scientific reports, 2018, 03-29, Volume: 8, Issue:1

    Topics: Animals; Apoptosis; Biomarkers; Catechin; Diet, Carbohydrate Loading; Diet, High-Fat; Disease Models, Animal; Female; Metabolic Syndrome; Mitochondria; Ovariectomy; Oxidative Stress; Plant Extracts; Primary Ovarian Insufficiency; Rats; Rats, Sprague-Dawley; Tea; Urinary Bladder, Overactive

2018
Epigallocatechingallate attenuates myocardial injury in a mouse model of heart failure through TGF‑β1/Smad3 signaling pathway.
    Molecular medicine reports, 2018, Volume: 17, Issue:6

    Topics: Animals; Apoptosis; Biomarkers; Catechin; Cytokines; Disease Models, Animal; Fibrosis; Heart Failure; Inflammation Mediators; Male; Mice; Myocardium; Oxidative Stress; Signal Transduction; Smad3 Protein; Transforming Growth Factor beta1; Ultrasonography

2018
Epigallocatechin-3-Gallate Protects and Prevents Paraquat-Induced Oxidative Stress and Neurodegeneration in Knockdown dj-1-β Drosophila melanogaster.
    Neurotoxicity research, 2018, Volume: 34, Issue:3

    Topics: Animals; Animals, Genetically Modified; Antioxidants; Catechin; Disease Models, Animal; Dose-Response Relationship, Drug; Drosophila melanogaster; Drosophila Proteins; Female; Herbicides; Lipid Peroxidation; Locomotion; Male; Minocycline; Nerve Tissue Proteins; Neurodegenerative Diseases; Neuroprotective Agents; Oxidative Stress; Paraquat; Protein Deglycase DJ-1; Tyrosine 3-Monooxygenase

2018
Epigallocatechin gallate targets FTO and inhibits adipogenesis in an mRNA m
    International journal of obesity (2005), 2018, Volume: 42, Issue:7

    Topics: 3T3-L1 Cells; Adipocytes; Adipogenesis; Alpha-Ketoglutarate-Dependent Dioxygenase FTO; Animals; Anti-Obesity Agents; Catechin; Disease Models, Animal; Mice; RNA-Binding Proteins; RNA, Messenger; Tea

2018
Procyanidin B2 prevents lupus nephritis development in mice by inhibiting NLRP3 inflammasome activation.
    Innate immunity, 2018, Volume: 24, Issue:5

    Topics: Animals; Antibodies, Antinuclear; Biflavonoids; Catechin; Cells, Cultured; Disease Models, Animal; Female; Humans; Inflammasomes; Kidney; Lupus Nephritis; Mice; Mice, Inbred MRL lpr; NLR Family, Pyrin Domain-Containing 3 Protein; Proanthocyanidins; RNA, Small Interfering; Signal Transduction

2018
Against NF-κB/thymic stromal lymphopoietin signaling pathway, catechin alleviates the inflammation in allergic rhinitis.
    International immunopharmacology, 2018, Volume: 61

    Topics: Animals; Anti-Inflammatory Agents; Catechin; Cells, Cultured; Cytokines; Disease Models, Animal; Epithelial Cells; Female; Humans; Immunoglobulin E; Inflammation; Interleukin-13; Interleukin-5; Mice; Mice, Inbred BALB C; NF-kappa B; Rhinitis, Allergic; Signal Transduction; Th1-Th2 Balance; Th2 Cells; Thymic Stromal Lymphopoietin

2018
Theaflavin alleviates inflammatory response and brain injury induced by cerebral hemorrhage via inhibiting the nuclear transcription factor kappa β-related pathway in rats.
    Drug design, development and therapy, 2018, Volume: 12

    Topics: Animals; Anti-Inflammatory Agents; Apoptosis; Behavior, Animal; Biflavonoids; Blood-Brain Barrier; Brain; Brain Edema; Brain Injuries; Capillary Permeability; Catechin; Cerebral Hemorrhage; Cytokines; Disease Models, Animal; Dose-Response Relationship, Drug; Encephalitis; Rats, Sprague-Dawley; Reactive Oxygen Species; Signal Transduction; Transcription Factor RelA

2018
Flavocoxid attenuates airway inflammation in ovalbumin-induced mouse asthma model.
    Chemico-biological interactions, 2018, 08-25, Volume: 292

    Topics: Animals; Asthma; Biomarkers; Catechin; Disease Models, Animal; Drug Combinations; Inflammation; Lung; Mice; Ovalbumin; Oxidative Stress

2018
Epigallocatechin-3-gallate protects against the exacerbation of allergic eosinophilic inflammation associated with obesity in mice.
    International immunopharmacology, 2018, Volume: 62

    Topics: Animals; Antioxidants; Asthma; Catechin; Disease Models, Animal; Eosinophils; Inflammation; Lung; Male; Mice, Inbred C57BL; Obesity; Oxidative Stress

2018
Theabrownin suppresses in vitro osteoclastogenesis and prevents bone loss in ovariectomized rats.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2018, Volume: 106

    Topics: Animals; Biomarkers; Bone Density Conservation Agents; Bone Remodeling; Catechin; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Femur; Humans; Mice; Osteoclasts; Osteogenesis; Osteoporosis, Postmenopausal; Ovariectomy; RANK Ligand; Rats, Wistar; RAW 264.7 Cells

2018
Green Tea Catechin Is an Alternative Immune Checkpoint Inhibitor that Inhibits PD-L1 Expression and Lung Tumor Growth.
    Molecules (Basel, Switzerland), 2018, Aug-18, Volume: 23, Issue:8

    Topics: Animals; Antineoplastic Agents, Phytogenic; B7-H1 Antigen; Catechin; Cell Line, Tumor; Disease Models, Animal; Gene Expression; Humans; Immunomodulation; Lung Neoplasms; Mice; Phosphorylation; Proto-Oncogene Proteins c-akt; Signal Transduction; STAT1 Transcription Factor; T-Lymphocyte Subsets; Tea; Xenograft Model Antitumor Assays

2018
Epigallocatechin Gallate Attenuates Bladder Dysfunction via Suppression of Oxidative Stress in a Rat Model of Partial Bladder Outlet Obstruction.
    Oxidative medicine and cellular longevity, 2018, Volume: 2018

    Topics: Animals; Anticarcinogenic Agents; Catechin; Disease Models, Animal; Male; Oxidative Stress; Rats; Rats, Sprague-Dawley; Urinary Bladder; Urinary Bladder Neck Obstruction

2018
(-)-Epicatechin inhibits development of dilated cardiomyopathy in δ sarcoglycan null mouse.
    Nutrition, metabolism, and cardiovascular diseases : NMCD, 2018, Volume: 28, Issue:11

    Topics: Animals; Atrial Natriuretic Factor; Cardiomyopathy, Dilated; Catechin; Coronary Vessels; Disease Models, Animal; Fibrosis; Male; Mice, Knockout; Myocytes, Cardiac; Natriuretic Peptide, Brain; Nitric Oxide Synthase Type III; Phosphatidylinositol 3-Kinase; Phosphorylation; Proto-Oncogene Proteins c-akt; Ribosomal Protein S6 Kinases, 70-kDa; Sarcoglycans; Signal Transduction; TOR Serine-Threonine Kinases; Vasoconstriction; Ventricular Function, Left; Ventricular Remodeling

2018
Enhanced oral bioavailability of EGCG using pH-sensitive polymeric nanoparticles: characterization and in vivo investigation on nephrotic syndrome rats.
    Drug design, development and therapy, 2018, Volume: 12

    Topics: Administration, Oral; Animals; Biological Availability; Calorimetry, Differential Scanning; Catechin; Crystallography, X-Ray; Disease Models, Animal; Drug Carriers; Drug Compounding; Drug Liberation; Hydrogen-Ion Concentration; Kidney; Microscopy, Electron, Transmission; Nanoparticles; Nephrotic Syndrome; Polymers; Powder Diffraction; Proteinuria; Rats, Sprague-Dawley; Renal Agents; Solubility

2018
Epigallocatechin‑3‑gallate protects against secondary osteoporosis in a mouse model via the Wnt/β‑catenin signaling pathway.
    Molecular medicine reports, 2018, Volume: 18, Issue:5

    Topics: Animals; beta Catenin; Calcium; Cartilage; Catechin; Cell Proliferation; Cyclin D1; Disease Models, Animal; Humans; Mice; Osteoporosis; PPAR gamma; Tea; Wnt Signaling Pathway

2018
A New Therapeutic Approach for Brain Delivery of Epigallocatechin Gallate: Development and Characterization Studies.
    Current drug delivery, 2019, Volume: 16, Issue:1

    Topics: Animals; Behavior, Animal; Biological Availability; Blood-Brain Barrier; Catechin; Cerebral Infarction; Disease Models, Animal; Drug Compounding; Drug Liberation; Emulsions; Humans; Lipids; Male; Memory Disorders; Mice; Nanoparticles; Neuroprotective Agents; Treatment Outcome

2019
Effects of Epigallocatechin Gallate on Behavioral and Cognitive Impairments, Hypothalamic-Pituitary-Adrenal Axis Dysfunction, and Alternations in Hippocampal BDNF Expression Under Single Prolonged Stress.
    Journal of medicinal food, 2018, Volume: 21, Issue:10

    Topics: Animals; Brain-Derived Neurotrophic Factor; Catechin; Cognitive Dysfunction; Cyclic AMP Response Element-Binding Protein; Disease Models, Animal; Hippocampus; Humans; Male; Maze Learning; Memory; Pituitary-Adrenal System; Rats; Stress Disorders, Post-Traumatic; Stress, Physiological

2018
Epigallocatechin-3 gallate prevents pressure overload-induced heart failure by up-regulating SERCA2a via histone acetylation modification in mice.
    PloS one, 2018, Volume: 13, Issue:10

    Topics: Acetylation; Animals; Aortic Diseases; Cardiovascular Agents; Catechin; Constriction, Pathologic; Disease Models, Animal; Heart Failure; Histone Deacetylase 1; Histones; Male; Mice, Inbred C57BL; Promoter Regions, Genetic; Protective Agents; Random Allocation; RNA, Messenger; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Up-Regulation

2018
(‑)Epigallocatechin‑3‑gallate attenuates anesthesia‑induced memory deficit in young mice via modulation of nitric oxide expression.
    Molecular medicine reports, 2018, Volume: 18, Issue:6

    Topics: Anesthesia; Animals; Antioxidants; Apoptosis; Arginine; Biomarkers; Catechin; Disease Models, Animal; Indazoles; Male; Memory; Memory Disorders; Mice; Neuroprotective Agents; Nitric Oxide; Nitric Oxide Synthase Type I; Oxidative Stress

2018
Effects of (-)-Epigallocatechin Gallate (EGCG) on Energy Expenditure and Microglia-Mediated Hypothalamic Inflammation in Mice Fed a High-Fat Diet.
    Nutrients, 2018, Nov-05, Volume: 10, Issue:11

    Topics: Adipose Tissue, Brown; Animals; Biomarkers; Blood Glucose; Catechin; Cholesterol; Diet, High-Fat; Disease Models, Animal; Energy Metabolism; Hypothalamus; Inflammation Mediators; Male; Mice; Mice, Inbred C57BL; Mice, Obese; Microglia; NF-kappa B; Obesity; Polyphenols; STAT3 Transcription Factor; Tea; Triglycerides

2018
Epicatechin alleviates inflammation in lipopolysaccharide-induced acute lung injury in mice by inhibiting the p38 MAPK signaling pathway.
    International immunopharmacology, 2019, Volume: 66

    Topics: Acute Lung Injury; Animals; Anti-Inflammatory Agents; Biflavonoids; Catechin; Disease Models, Animal; Humans; Inflammation; Lipopolysaccharides; Male; MAP Kinase Signaling System; Mice; Mice, Inbred C57BL; p38 Mitogen-Activated Protein Kinases; Proanthocyanidins; Protein Binding

2019
G3BP1 promotes DNA binding and activation of cGAS.
    Nature immunology, 2019, Volume: 20, Issue:1

    Topics: Animals; Autoantigens; Autoimmune Diseases of the Nervous System; Catechin; Clustered Regularly Interspaced Short Palindromic Repeats; Cytosol; Disease Models, Animal; DNA; DNA Helicases; Exodeoxyribonucleases; HEK293 Cells; HeLa Cells; Humans; Interferons; Mice; Mice, Knockout; Multiprotein Complexes; Nervous System Malformations; Neuroprotective Agents; Nucleotidyltransferases; Phosphoproteins; Poly-ADP-Ribose Binding Proteins; Protein Binding; RNA Helicases; RNA Recognition Motif Proteins

2019
Gelatin-epigallocatechin gallate nanoparticles with hyaluronic acid decoration as eye drops can treat rabbit dry-eye syndrome effectively via inflammatory relief.
    International journal of nanomedicine, 2018, Volume: 13

    Topics: Animals; Catechin; Cell Survival; Cytokines; Disease Models, Animal; Dry Eye Syndromes; Epithelial Cells; Epithelium, Corneal; Gelatin; Humans; Hyaluronic Acid; Inflammation; Male; Nanoparticles; Ophthalmic Solutions; Particle Size; Rabbits; Rats; Sus scrofa; Tears; Treatment Outcome

2018
Development of transgenic Caenorhabditis elegans expressing human transthyretin as a model for drug screening.
    Scientific reports, 2018, 12-14, Volume: 8, Issue:1

    Topics: Amyloid Neuropathies, Familial; Animals; Animals, Genetically Modified; Caenorhabditis elegans; Catechin; Disease Models, Animal; Drug Evaluation, Preclinical; Green Fluorescent Proteins; Humans; Locomotion; Longevity; Neuroprotective Agents; Prealbumin; Recombinant Fusion Proteins; Staining and Labeling

2018
"Cell-addictive" dual-target traceable nanodrug for Parkinson's disease treatment via flotillins pathway.
    Theranostics, 2018, Volume: 8, Issue:19

    Topics: alpha-Synuclein; Animals; Animals, Genetically Modified; Catechin; Cell Line; Disease Models, Animal; Dopaminergic Neurons; Drug Carriers; Humans; Membrane Proteins; Mice; Molecular Targeted Therapy; Nanoparticles; Neuroprotective Agents; Parkinson Disease; Protein Aggregation, Pathological; Treatment Outcome

2018
Combined treatment with the phenolics (-)-epigallocatechin-3-gallate and ferulic acid improves cognition and reduces Alzheimer-like pathology in mice.
    The Journal of biological chemistry, 2019, 02-22, Volume: 294, Issue:8

    Topics: Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Behavior, Animal; Catechin; Cognitive Dysfunction; Coumaric Acids; Disease Models, Animal; Drug Therapy, Combination; Humans; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Presenilin-1

2019
Anti-inflammatory effects of new catechin derivatives in a hapten-induced mouse contact dermatitis model.
    European journal of pharmacology, 2019, Feb-15, Volume: 845

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Catechin; Cytokines; Dermatitis, Allergic Contact; Disease Models, Animal; Electron Spin Resonance Spectroscopy; Haptens; Mice; Mice, Inbred BALB C

2019
Anti-arthritic and anti-inflammatory effects of (-)-Epicatechin-3-O-β-d-allopyranoside, a constituent of Davallia formosana.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2019, Volume: 52

    Topics: Animals; Anti-Inflammatory Agents; Arthritis, Experimental; Arthritis, Rheumatoid; Bone and Bones; Cartilage; Catechin; Collagen Type II; Cytokines; Disease Models, Animal; Edema; Ferns; Freund's Adjuvant; Glycosides; Immunoglobulin G; Male; Matrix Metalloproteinase 9; Mice; Mice, Inbred DBA; Nitric Oxide; Plant Extracts; RAW 264.7 Cells

2019
Diet supplemented with phytochemical epigallocatechin gallate and probiotic Lactobacillus fermentum confers second generation synbiotic effects by modulating cellular immune responses and antioxidant capacity in aging mice.
    European journal of nutrition, 2019, Volume: 58, Issue:7

    Topics: Aging; Animals; Antioxidants; Catechin; Diet; Disease Models, Animal; Immunity, Cellular; Immunosenescence; Limosilactobacillus fermentum; Male; Mice; Oxidative Stress; Probiotics; Synbiotics

2019
Theaflavins Improve Memory Impairment and Depression-Like Behavior by Regulating Microglial Activation.
    Molecules (Basel, Switzerland), 2019, Jan-28, Volume: 24, Issue:3

    Topics: Animals; Anti-Inflammatory Agents; Antidepressive Agents; Behavior, Animal; Biflavonoids; Catechin; Cells, Cultured; Depression; Disease Models, Animal; Memory; Mice; Microglia; Neuroprotective Agents; Tea

2019
RNA-seq analysis of diet-driven obesity and anti-obesity effects of quercetin glucoside or epigallocatechin gallate in Drosophila adults.
    European review for medical and pharmacological sciences, 2019, Volume: 23, Issue:2

    Topics: Animals; Anti-Obesity Agents; Body Weight; Catechin; Diet, High-Fat; Disease Models, Animal; Drosophila; Drug Evaluation, Preclinical; Female; Gene Expression Regulation; Glucosides; Humans; Lipid Metabolism; Male; Metabolomics; Obesity; Oxidative Stress; Quercetin; RNA-Seq; RNA, Messenger; Species Specificity

2019
Tea's value as a cancer therapy is steeped in uncertainty.
    Nature, 2019, Volume: 566, Issue:7742

    Topics: Animals; Biological Products; Case-Control Studies; Catechin; Cell Line, Tumor; China; Cohort Studies; Dietary Supplements; Disease Models, Animal; Female; Humans; Incidence; Japan; Life Style; Male; Metabolic Syndrome; Mice; Neoplasms; Plant Extracts; Prostatic Neoplasms; Sex Factors; Smoking; Sunitinib; Tea; Uncertainty

2019
Ingredients in Zijuan Pu'er Tea Extract Alleviate β-Amyloid Peptide Toxicity in a
    Molecules (Basel, Switzerland), 2019, Feb-18, Volume: 24, Issue:4

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Animals, Genetically Modified; Antioxidants; Biflavonoids; Caenorhabditis elegans; Caffeine; Catechin; Disease Models, Animal; Gene Expression Regulation; Humans; Oxidative Stress; Paralysis; Plant Extracts; Proanthocyanidins; Reactive Oxygen Species; Signal Transduction; Superoxide Dismutase; Tea

2019
Green tea catechins alleviate autoimmune symptoms and visual impairment in a murine model for human chronic intraocular inflammation by inhibiting Th17-associated pro-inflammatory gene expression.
    Scientific reports, 2019, 02-19, Volume: 9, Issue:1

    Topics: Animals; Catechin; Disease Models, Animal; Electroretinography; Inflammation; Interleukin-17; Interleukin-6; Mice; Microscopy, Confocal; Papilledema; Tea; Th17 Cells; Tomography, Optical Coherence; Tumor Necrosis Factor-alpha; Uveitis; Vision Disorders

2019
Dietary supplementation with procyanidin-rich Pinus pinaster extract is associated with attenuated Ehrlich tumor development in mice.
    Nutrition research (New York, N.Y.), 2019, Volume: 62

    Topics: Animals; Biflavonoids; Carcinoma, Ehrlich Tumor; Catechin; Dietary Supplements; Disease Models, Animal; Male; Mice; Mice, Inbred BALB C; Pinus; Plant Extracts; Proanthocyanidins

2019
(-)-Epicatechin attenuates hepatic sinusoidal obstruction syndrome by inhibiting liver oxidative and inflammatory injury.
    Redox biology, 2019, Volume: 22

    Topics: Animals; Antioxidants; Biomarkers; Catechin; Chaperonin 60; Disease Models, Animal; Hepatic Veno-Occlusive Disease; Inflammation Mediators; Liver; Male; Mice; Mice, Transgenic; Models, Molecular; Molecular Conformation; NF-E2-Related Factor 2; Oxidation-Reduction; Oxidative Stress; Rats; Reactive Oxygen Species; Signal Transduction; Structure-Activity Relationship

2019
Procyanidin B2 protects against diet-induced obesity and non-alcoholic fatty liver disease
    World journal of gastroenterology, 2019, Feb-28, Volume: 25, Issue:8

    Topics: Animals; Bacteroidetes; Biflavonoids; Biomarkers; Body Weight; Catechin; Diet, High-Fat; Disease Models, Animal; Gastrointestinal Microbiome; Humans; Insulin Resistance; Lipopolysaccharides; Liver; Male; Non-alcoholic Fatty Liver Disease; Obesity; Proanthocyanidins; Protective Agents; Rabbits; RNA, Ribosomal, 16S; Treatment Outcome; Triglycerides

2019
Epigallocatechin-3-Gallate Attenuates Adriamycin-Induced Focal Segmental Glomerulosclerosis via Suppression of Oxidant Stress and Apoptosis by Targeting Hypoxia-Inducible Factor-1α/ Angiopoietin-Like 4 Pathway.
    Pharmacology, 2019, Volume: 103, Issue:5-6

    Topics: Angiopoietin-Like Protein 4; Animals; Antioxidants; Apoptosis; Blotting, Western; Catechin; Disease Models, Animal; Doxorubicin; Fluorescent Antibody Technique; Glomerulosclerosis, Focal Segmental; Hypoxia-Inducible Factor 1, alpha Subunit; In Situ Nick-End Labeling; Mice; Mice, Inbred C57BL; Oxidative Stress; Reactive Oxygen Species; Real-Time Polymerase Chain Reaction

2019
(-)-Epigallocatechin-3-Gallate Protects Against Lithium-Pilocarpine-Induced Epilepsy by Inhibiting the Toll-Like Receptor 4 (TLR4)/Nuclear Factor-κB (NF-κB) Signaling Pathway.
    Medical science monitor : international medical journal of experimental and clinical research, 2019, Mar-07, Volume: 25

    Topics: Animals; Catechin; Disease Models, Animal; Epilepsy; Epilepsy, Temporal Lobe; Hippocampus; Lithium; Long-Term Potentiation; Male; Neurons; Neuroprotective Agents; NF-kappa B; Pilocarpine; Rats; Rats, Sprague-Dawley; Seizures; Signal Transduction; Toll-Like Receptor 4

2019
Prenatal treatment with EGCG enriched green tea extract rescues GAD67 related developmental and cognitive defects in Down syndrome mouse models.
    Scientific reports, 2019, 03-08, Volume: 9, Issue:1

    Topics: Animals; Brain; Catechin; Cognition; Disease Models, Animal; Down Syndrome; Dyrk Kinases; Female; Glutamate Decarboxylase; Interneurons; Maternal-Fetal Exchange; Maze Learning; Mice; Mice, Inbred C57BL; Mice, Transgenic; Pregnancy; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Tea

2019
Dual-drug loaded nanoparticles of Epigallocatechin-3-gallate (EGCG)/Ascorbic acid enhance therapeutic efficacy of EGCG in a APPswe/PS1dE9 Alzheimer's disease mice model.
    Journal of controlled release : official journal of the Controlled Release Society, 2019, 05-10, Volume: 301

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Antioxidants; Ascorbic Acid; Brain; Catechin; Disease Models, Animal; Drug Carriers; Drug Liberation; Endothelial Cells; Male; Mice, Inbred C57BL; Mice, Transgenic; Nanoparticles; Polyethylene Glycols; Polylactic Acid-Polyglycolic Acid Copolymer; Rats

2019
Avocado seeds (Persea americana Mill.) prevents indomethacin-induced gastric ulcer in mice.
    Food research international (Ottawa, Ont.), 2019, Volume: 119

    Topics: Animals; Antioxidants; Brazil; Catechin; Chromatography, High Pressure Liquid; Disease Models, Animal; Flavonoids; Indomethacin; Lipid Peroxidation; Male; Mice; Oxidation-Reduction; Persea; Phenols; Plant Extracts; Seeds; Stomach Ulcer; Superoxide Dismutase

2019
Epicatechin protective effects on bleomycin-induced pulmonary oxidative stress and fibrosis in mice.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2019, Volume: 114

    Topics: Animals; Antioxidants; Biomarkers; Bleomycin; Catalase; Catechin; Disease Models, Animal; Glutathione Peroxidase; Hydroxyproline; Inflammation; Lung; Male; Malondialdehyde; Mice; Oxidative Stress; Protective Agents; Pulmonary Fibrosis; Superoxide Dismutase

2019
Epigallocatechin gallate ameliorates airway inflammation by regulating Treg/Th17 imbalance in an asthmatic mouse model.
    International immunopharmacology, 2019, Volume: 72

    Topics: Animals; Anti-Inflammatory Agents; Asthma; Catechin; Disease Models, Animal; Female; Forkhead Transcription Factors; Immunoglobulin E; Interleukin-10; Interleukin-17; Lung; Mice, Inbred BALB C; Nuclear Receptor Subfamily 1, Group F, Member 3; T-Lymphocytes, Regulatory; Th17 Cells

2019
Downregulated Wnt/β-catenin signalling in the Down syndrome hippocampus.
    Scientific reports, 2019, 05-13, Volume: 9, Issue:1

    Topics: Adaptor Proteins, Signal Transducing; Aged; Alzheimer Disease; Animals; Axin Protein; Catechin; Chromosomes, Human, Pair 21; Disease Models, Animal; Down Syndrome; Down-Regulation; Dyrk Kinases; Female; HEK293 Cells; HeLa Cells; Hippocampus; Humans; Male; Mice; Middle Aged; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; RNA-Seq; Wnt Signaling Pathway

2019
Caffeine-free hawk tea lowers cholesterol by reducing free cholesterol uptake and the production of very-low-density lipoprotein.
    Communications biology, 2019, Volume: 2

    Topics: Animals; Anticholesteremic Agents; Biological Transport, Active; Caffeine; Catechin; Cholesterol; Disease Models, Animal; Dyslipidemias; Feeder Cells; Gastrointestinal Microbiome; Hep G2 Cells; Humans; Kaempferols; Lipid Metabolism; Lipoproteins, VLDL; Litsea; Liver; Male; Models, Biological; Quercetin; Rats; Rats, Sprague-Dawley; Receptors, LDL; Sterol Regulatory Element Binding Protein 2; Teas, Medicinal

2019
Epigallocatechin-3-Gallate Prevents Acute Gout by Suppressing NLRP3 Inflammasome Activation and Mitochondrial DNA Synthesis.
    Molecules (Basel, Switzerland), 2019, Jun-06, Volume: 24, Issue:11

    Topics: Animals; Caspase 1; Catechin; Disease Models, Animal; DNA, Mitochondrial; Gout; Humans; Inflammasomes; Inflammation; Interleukin-1beta; Macrophages; Mice; Mice, Inbred C57BL; NLR Family, Pyrin Domain-Containing 3 Protein; Reactive Oxygen Species; Uric Acid

2019
(-)-Epicatechin reduces adiposity in male offspring of obese rats.
    Journal of developmental origins of health and disease, 2020, Volume: 11, Issue:1

    Topics: Adiposity; Animals; Body Weight; Catechin; Diet, High-Fat; Disease Models, Animal; Female; Humans; Insulin Resistance; Leptin; Male; Obesity, Maternal; Pregnancy; Prenatal Exposure Delayed Effects; Rats

2020
Epigallocatechin-3-gallate ameliorates lipopolysaccharide-induced acute lung injury by suppression of TLR4/NF-κB signaling activation.
    Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, 2019, Volume: 52, Issue:7

    Topics: Acute Lung Injury; Animals; Catechin; Disease Models, Animal; Lipopolysaccharides; Male; Mice; Mice, Inbred BALB C; NF-kappa B; Signal Transduction; Toll-Like Receptor 4

2019
Low dose Epigallocatechin Gallate Alleviates Experimental Colitis by Subduing Inflammatory Cells and Cytokines, and Improving Intestinal Permeability.
    Nutrients, 2019, Jul-29, Volume: 11, Issue:8

    Topics: Animals; Anti-Inflammatory Agents; Catechin; Colitis; Colon; Cytokines; Dextran Sulfate; Disease Models, Animal; Gastrointestinal Agents; Inflammation Mediators; Macrophages; Male; Mice, Inbred C57BL; Permeability; T-Lymphocytes

2019
Amelioration of cognitive impairment and neurodegeneration by catechin hydrate in rat model of streptozotocin-induced experimental dementia of Alzheimer's type.
    Neurochemistry international, 2013, Volume: 62, Issue:4

    Topics: Acetylcholinesterase; Alzheimer Disease; Animals; Behavior, Animal; Catechin; Choline O-Acetyltransferase; Cognition Disorders; Disease Models, Animal; Glutathione; Hippocampus; Interleukin-1beta; Male; Maze Learning; Nitric Oxide Synthase Type II; Rats; Rats, Wistar; Streptozocin; Tumor Necrosis Factor-alpha

2013
Protective effects of a catechin-rich extract on the hippocampal formation and spatial memory in aging rats.
    Behavioural brain research, 2013, Jun-01, Volume: 246

    Topics: Age Factors; Animals; Catechin; Dendrites; Disease Models, Animal; Hippocampus; Lysosomes; Male; Malondialdehyde; Maze Learning; Memory Disorders; Microscopy, Electron, Transmission; Mitochondria; Neuroprotective Agents; Protein Carbonylation; Pyramidal Cells; Random Allocation; Rats; Rats, Wistar; Silver Staining; Space Perception

2013
Epigallocatechin-3-gallate is a potent phytochemical inhibitor of intimal hyperplasia in the wire-injured carotid artery.
    Journal of vascular surgery, 2013, Volume: 58, Issue:5

    Topics: Animals; Cardiovascular Agents; Carotid Artery Injuries; Carotid Artery, Common; Carotid Intima-Media Thickness; Catechin; Cell Proliferation; Disease Models, Animal; Disulfides; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Hyperplasia; Injections, Intraperitoneal; Isothiocyanates; Male; Neointima; Protein Kinase Inhibitors; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes; Sulfinic Acids; Sulfoxides; Time Factors

2013
Beneficial effects of green tea catechin on massive hepatectomy model in rats.
    Journal of gastroenterology, 2014, Volume: 49, Issue:4

    Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Catalase; Catechin; Cell Count; Cyclooxygenase 2; Disease Models, Animal; Free Radical Scavengers; Hepatectomy; Kupffer Cells; L-Lactate Dehydrogenase; Liver; Liver Regeneration; Male; Malondialdehyde; MAP Kinase Signaling System; Mitogen-Activated Protein Kinases; NF-kappa B; Nitric Oxide Synthase Type II; Phosphorylation; Phytotherapy; Plant Extracts; Proliferating Cell Nuclear Antigen; Rats; Rats, Wistar; RNA, Messenger; Superoxide Dismutase; Tea; Tumor Necrosis Factor-alpha

2014
Green tea epigallocatechin-3-gallate attenuates Porphyromonas gingivalis-induced atherosclerosis.
    Pathogens and disease, 2013, Volume: 67, Issue:1

    Topics: Animals; Anti-Inflammatory Agents; Aorta; Atherosclerosis; Bacteroidaceae Infections; Biomarkers; Catechin; Disease Models, Animal; Gene Expression Profiling; Male; Mice; Mice, Knockout; Porphyromonas gingivalis; Tea Tree Oil; Treatment Outcome

2013
[Research on EGCG improving the degenerative changes of the brain in AD model mice induced with chemical drugs].
    Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 2012, Volume: 35, Issue:10

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Brain; Catechin; Disease Models, Animal; Female; Galactose; Gene Expression Regulation; Hippocampus; Mice; Neurons; Neuroprotective Agents; Phytotherapy; Tea

2012
Effect of dietary polyphenols from hop (Humulus lupulus L.) pomace on adipose tissue mass, fasting blood glucose, hemoglobin A1c, and plasma monocyte chemotactic protein-1 levels in OLETF rats.
    Journal of oleo science, 2013, Volume: 62, Issue:5

    Topics: Adipose Tissue; Animals; Blood Glucose; Catechin; Diabetes Mellitus, Type 2; Dietary Supplements; Disease Models, Animal; Fasting; Glucosephosphate Dehydrogenase; Humulus; Malate Dehydrogenase; Male; Rats; Sterol Regulatory Element Binding Protein 1; Triglycerides

2013
(-)-Epigallocatechin-3-gallate alleviates spatial memory impairment in APP/PS1 mice by restoring IRS-1 signaling defects in the hippocampus.
    Molecular and cellular biochemistry, 2013, Volume: 380, Issue:1-2

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Blotting, Western; Catechin; Disease Models, Animal; Female; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Hippocampus; Immunohistochemistry; Insulin Receptor Substrate Proteins; JNK Mitogen-Activated Protein Kinases; Maze Learning; Memory Disorders; Mice; Mice, Inbred C57BL; Mice, Transgenic; Peptide Fragments; Phosphorylation; Presenilin-1; Proto-Oncogene Proteins c-akt; Serine; Signal Transduction; Tumor Necrosis Factor-alpha

2013
Epigallocatechin-3-gallate reduces myometrial infiltration, uterine hyperactivity, and stress levels and alleviates generalized hyperalgesia in mice induced with adenomyosis.
    Reproductive sciences (Thousand Oaks, Calif.), 2013, Volume: 20, Issue:12

    Topics: Adenomyosis; Animals; Biomarkers; Catechin; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Hydrocortisone; Hyperalgesia; Mice; Mice, Inbred ICR; Myometrium; Pain Threshold; Reaction Time; Stress, Physiological; Tamoxifen; Time Factors; Uterine Contraction

2013
Anti-edema effect of epigallocatechin gallate on spinal cord injury in rats.
    Brain research, 2013, Aug-21, Volume: 1527

    Topics: Animals; Aquaporin 4; Blotting, Western; Catechin; Disease Models, Animal; Edema; Glial Fibrillary Acidic Protein; Immunohistochemistry; Male; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Spinal Cord Injuries

2013
Extract of Ulmus macrocarpa Hance prevents thrombus formation through antiplatelet activity.
    Molecular medicine reports, 2013, Volume: 8, Issue:3

    Topics: Adenosine Diphosphate; Animals; Catechin; Chromatography, High Pressure Liquid; Collagen; Disease Models, Animal; Fibrinolytic Agents; Male; Plant Extracts; Platelet Aggregation; Rats; Rats, Sprague-Dawley; Thrombosis; Ulmus

2013
Exosome derived from epigallocatechin gallate treated breast cancer cells suppresses tumor growth by inhibiting tumor-associated macrophage infiltration and M2 polarization.
    BMC cancer, 2013, Sep-17, Volume: 13

    Topics: Animals; Anticarcinogenic Agents; Breast Neoplasms; Catechin; Cell Line, Tumor; Cell Proliferation; Chemokine CCL2; Disease Models, Animal; Exosomes; Female; Gene Expression Regulation, Neoplastic; I-kappa B Kinase; I-kappa B Proteins; Macrophage Colony-Stimulating Factor; Macrophages; Mice; MicroRNAs; Paracrine Communication

2013
Neuroprotection by (-)-epigallocatechin-3-gallate in a rat model of stroke is mediated through inhibition of endoplasmic reticulum stress.
    Molecular medicine reports, 2014, Volume: 9, Issue:1

    Topics: Animals; Apoptosis; Caspase 12; Catechin; Cyclic AMP Response Element-Binding Protein; Disease Models, Animal; Endoplasmic Reticulum Stress; Flavonoids; Heat-Shock Proteins; Male; Mitogen-Activated Protein Kinase Kinases; Neuroprotective Agents; Phosphorylation; Rats; Rats, Sprague-Dawley; Signal Transduction; Spectrin; Stroke; Transcription Factor CHOP; TRPC Cation Channels

2014
Epigallocatechin-3-gallate prevents tumor cell implantation/growth in an experimental rat bladder tumor model.
    International journal of oncology, 2014, Volume: 44, Issue:1

    Topics: Animals; Catechin; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Disease Models, Animal; Female; Humans; Mitomycin; Neoplasms, Experimental; Rats; Urinary Bladder Neoplasms

2014
Epigallocatechin-3-gallate prevents autoimmune-associated down- regulation of p21 in salivary gland cells through a p53-independent pathway.
    Inflammation & allergy drug targets, 2014, Volume: 13, Issue:1

    Topics: Animals; Anticarcinogenic Agents; Catechin; Cell Line, Tumor; Cyclin-Dependent Kinase Inhibitor p21; Diabetes Mellitus, Type 1; Disease Models, Animal; Down-Regulation; Epithelial Cells; Mice; Mice, Inbred BALB C; Mice, Inbred NOD; Proliferating Cell Nuclear Antigen; Retinoblastoma Protein; Salivary Glands; Sjogren's Syndrome; Tumor Suppressor Protein p53; Xerostomia

2014
Epigallocatechin-3-gallate (EGCG) attenuates concanavalin A-induced hepatic injury in mice.
    Acta histochemica, 2014, Volume: 116, Issue:4

    Topics: Animals; Catechin; Chemical and Drug Induced Liver Injury; Concanavalin A; Disease Models, Animal; Male; Mice, Inbred C57BL; Oxidative Stress; Toll-Like Receptors; Tumor Necrosis Factor-alpha

2014
Epigallocatechin gallate inhibits oxidative stress-induced DNA damage and apoptosis in MRL-Fas(lpr) mice with autoimmune sialadenitis via upregulation of heme oxygenase-1 and Bcl-2.
    Autoimmunity, 2014, Volume: 47, Issue:1

    Topics: Animals; Antioxidants; Apoptosis; Autoantigens; Autoimmune Diseases; Catechin; Disease Models, Animal; DNA Damage; Gene Expression Regulation; Heme Oxygenase-1; Mice; Mice, Inbred MRL lpr; Oxidative Stress; Proto-Oncogene Proteins c-bcl-2; Severity of Illness Index; Sialadenitis; Submandibular Gland

2014
Dietary supplementation with a low dose of (-)-epigallocatechin-3-gallate reduces pro-inflammatory responses in peripheral leukocytes of non-obese type 2 diabetic GK rats.
    Journal of nutritional science and vitaminology, 2013, Volume: 59, Issue:6

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Analysis of Variance; Animals; Catechin; Chemokines; Corn Oil; Cytokines; Deoxyguanosine; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Diet; Diet, High-Fat; Dietary Fats; Dietary Supplements; Disease Models, Animal; Inflammation; Leukocytes; Male; Malondialdehyde; Oxidative Stress; Polymerase Chain Reaction; Rats; Rats, Wistar

2013
Effects of (-)-epicatechin on a diet-induced rat model of cardiometabolic risk factors.
    European journal of pharmacology, 2014, Apr-05, Volume: 728

    Topics: Animals; Blood Glucose; Blood Pressure; Catechin; Diet, High-Fat; Disease Models, Animal; Eating; Energy Metabolism; Feces; Heart Diseases; Male; Obesity; Rats; Rats, Wistar; Risk Factors; Triglycerides; Weight Gain

2014
Safety and chemopreventive effect of Polyphenon E in preventing early and metastatic progression of prostate cancer in TRAMP mice.
    Cancer prevention research (Philadelphia, Pa.), 2014, Volume: 7, Issue:4

    Topics: Adenocarcinoma; Animals; Catechin; Disease Models, Animal; Disease Progression; Humans; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Prostatic Neoplasms; Safety

2014
Epigallocatechin-3-gallate restores the Bcl-2 expression in liver of young rats challenged with hypercholesterolemia but not in aged rats: an insight into its disparity of efficacy on advancing age.
    Food & function, 2014, Volume: 5, Issue:5

    Topics: Age Factors; Animals; Apoptosis; Catechin; Disease Models, Animal; Humans; Hypercholesterolemia; Liver; Male; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Wistar

2014
Effect of topical epigallocatechin gallate on corneal neovascularization in rabbits.
    Cornea, 2014, Volume: 33, Issue:5

    Topics: Administration, Topical; Angiogenesis Inhibitors; Animals; Antioxidants; Blotting, Western; Catechin; Cornea; Corneal Neovascularization; Cyclooxygenase 2; Disease Models, Animal; Electrophoresis, Polyacrylamide Gel; Ophthalmic Solutions; Rabbits; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Vascular Endothelial Growth Factor A

2014
Effect of epicatechin gallate dietary supplementation on transgenic Drosophila model of Parkinson's disease.
    Journal of dietary supplements, 2014, Volume: 11, Issue:2

    Topics: alpha-Synuclein; Animals; Animals, Genetically Modified; Antioxidants; Apoptosis; Brain; Camellia sinensis; Catechin; Dietary Supplements; Disease Models, Animal; Dopaminergic Neurons; Dose-Response Relationship, Drug; Drosophila melanogaster; Drosophila Proteins; Humans; Lipid Peroxidation; Locomotion; Oxidative Stress; Parkinson Disease; Phytotherapy; Plant Extracts

2014
(-)-Epicatechin mitigates high-fructose-associated insulin resistance by modulating redox signaling and endoplasmic reticulum stress.
    Free radical biology & medicine, 2014, Volume: 72

    Topics: Animals; Antioxidants; Blotting, Western; Catechin; Dietary Supplements; Disease Models, Animal; Endoplasmic Reticulum Stress; Fructose; Insulin Resistance; Male; Metabolic Syndrome; Oxidation-Reduction; Rats; Rats, Wistar; Real-Time Polymerase Chain Reaction; Signal Transduction

2014
(-)-Epigallocatechin-3-gallate attenuated myocardial mitochondrial dysfunction and autophagy in diabetic Goto-Kakizaki rats.
    Free radical research, 2014, Volume: 48, Issue:8

    Topics: Animals; Autophagy; Catechin; Diabetes Mellitus, Experimental; Disease Models, Animal; Male; Mitochondria, Heart; Oxidative Stress; Rats; Rats, Wistar

2014
Identification of epicatechin as one of the key bioactive constituents of polyphenol-enriched extracts that demonstrate an anti-allergic effect in a murine model of food allergy.
    The British journal of nutrition, 2014, Aug-14, Volume: 112, Issue:3

    Topics: Animals; Anti-Allergic Agents; Biological Availability; Catechin; Chymases; Cytokines; Disease Models, Animal; Female; Food Hypersensitivity; Fruit; Gene Expression; Immunoglobulin E; Immunoglobulin G; Intestine, Small; Lymph Nodes; Malus; Mesentery; Mice; Mice, Inbred BALB C; Ovalbumin; Plant Extracts; Polyphenols

2014
(-)-Epigallocatechin-3-gallate modulates spinal cord neuronal degeneration by enhancing growth-associated protein 43, B-cell lymphoma 2, and decreasing B-cell lymphoma 2-associated x protein expression after sciatic nerve crush injury.
    Journal of neurotrauma, 2015, Feb-01, Volume: 32, Issue:3

    Topics: Animals; bcl-X Protein; Catechin; Disease Models, Animal; GAP-43 Protein; Immunohistochemistry; Male; Nerve Crush; Nerve Degeneration; Neuroprotective Agents; Peripheral Nerve Injuries; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Wistar; Real-Time Polymerase Chain Reaction; Recovery of Function; Reverse Transcriptase Polymerase Chain Reaction; Sciatic Nerve; Spinal Cord

2015
Amelioration of lipid profile and level of antioxidant activities by epigallocatechin-gallate in a rat model of atherogenesis.
    Heart, lung & circulation, 2014, Volume: 23, Issue:12

    Topics: Animals; Antioxidants; Atherosclerosis; Catechin; Diet, Atherogenic; Disease Models, Animal; Lipids; Male; Rats; Rats, Wistar

2014
Epigallocatechin-3-gallate and tetracycline differently affect ataxin-3 fibrillogenesis and reduce toxicity in spinocerebellar ataxia type 3 model.
    Human molecular genetics, 2014, Dec-15, Volume: 23, Issue:24

    Topics: Amyloid; Animals; Ataxin-3; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Catechin; Cell Survival; Chlorocebus aethiops; COS Cells; Disease Models, Animal; Gene Expression; Green Fluorescent Proteins; Humans; Hydrogen Bonding; Machado-Joseph Disease; Microscopy, Atomic Force; Nerve Tissue Proteins; Neuroprotective Agents; Protein Aggregates; Recombinant Fusion Proteins; Spectroscopy, Fourier Transform Infrared; Tetracycline

2014
Green tea extract treatment alleviates ocular inflammation in a rat model of endotoxin-induced uveitis.
    PloS one, 2014, Volume: 9, Issue:8

    Topics: Animals; Aqueous Humor; Catechin; Disease Models, Animal; Endotoxins; Inflammation; Lipopolysaccharides; Neutrophil Infiltration; Plant Extracts; Rats; Rats, Sprague-Dawley; Tea; Uveitis

2014
The therapeutic effects of EGCG on vitiligo.
    Fitoterapia, 2014, Volume: 99

    Topics: Animals; Anti-Inflammatory Agents; Catechin; CD8-Positive T-Lymphocytes; Disease Models, Animal; Female; Hydroquinones; Interferon-gamma; Interleukin-6; Melanocytes; Mice; Mice, Inbred C57BL; Microscopy, Confocal; Skin Pigmentation; Transcriptome; Tumor Necrosis Factor-alpha; Vitiligo

2014
Tea component, epigallocatechin gallate, potentiates anticataleptic and locomotor-sensitizing effects of caffeine in mice.
    Behavioural pharmacology, 2015, Volume: 26, Issue:1-2

    Topics: Animals; Antipsychotic Agents; Caffeine; Catalepsy; Catechin; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Haloperidol; Lipid Peroxidation; Male; Mice; Motor Activity; Parkinsonian Disorders; Tea

2015
Oligonol improves memory and cognition under an amyloid β(25-35)-induced Alzheimer's mouse model.
    Nutrition research (New York, N.Y.), 2014, Volume: 34, Issue:7

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Awareness; Brain; Catechin; Cognition; Cognition Disorders; Disease Models, Animal; Dose-Response Relationship, Drug; Fruit; Kidney; Lipid Peroxidation; Liver; Male; Maze Learning; Memory; Memory Disorders; Mice, Inbred ICR; Nitric Oxide; Peptide Fragments; Phenols; Phytotherapy; Plant Extracts; Recognition, Psychology

2014
Epigallocatechin-3-gallate protects against cisplatin nephrotoxicity by inhibiting the apoptosis in mouse.
    International journal of clinical and experimental pathology, 2014, Volume: 7, Issue:8

    Topics: Animals; Antineoplastic Agents; Antioxidants; Apoptosis; Catechin; Cisplatin; Disease Models, Animal; Kidney; Kidney Diseases; Male; Mice; Mice, Inbred C57BL

2014
[Effects of EGCG on learning and memory ability expression level of NMDA receptor NR1 subunit protein in the brain of fatigue rats].
    Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology, 2014, Volume: 30, Issue:3

    Topics: Animals; Catechin; Disease Models, Animal; Fatigue; Learning; Male; Memory; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate

2014
Beneficial effects of dietary EGCG and voluntary exercise on behavior in an Alzheimer's disease mouse model.
    Journal of Alzheimer's disease : JAD, 2015, Volume: 44, Issue:2

    Topics: Administration, Oral; Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Anxiety; Catechin; Cerebral Cortex; Disease Models, Animal; Drinking Water; Female; Hippocampus; Housing, Animal; Humans; Male; Maze Learning; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Transgenic; Motor Activity; Nootropic Agents; Peptide Fragments

2015
(-)-Epicatechin prevents alterations in the metabolism of superoxide anion and nitric oxide in the hearts of L-NAME-treated rats.
    Food & function, 2015, Volume: 6, Issue:1

    Topics: Animals; Antihypertensive Agents; Catechin; Coronary Vessels; Dietary Supplements; Disease Models, Animal; Enzyme Activation; Fruit; Heart Ventricles; Hypertension; Male; NADPH Oxidases; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type III; Phosphorylation; Protein Processing, Post-Translational; Random Allocation; Rats, Sprague-Dawley; Stereoisomerism; Superoxides; Vegetables

2015
Novel Epigenetic Regulation of Alpha-Synuclein Expression in Down Syndrome.
    Molecular neurobiology, 2016, Volume: 53, Issue:1

    Topics: alpha-Synuclein; Animals; Catechin; Disease Models, Animal; DNA Methylation; Down Syndrome; Epigenesis, Genetic; Mice; Promoter Regions, Genetic

2016
Anti-allergic effect of intranasal administration of type-A procyanidin polyphenols based standardized extract of cinnamon bark in ovalbumin sensitized BALB/c mice.
    Phytotherapy research : PTR, 2015, Volume: 29, Issue:3

    Topics: Administration, Intranasal; Animals; Anti-Allergic Agents; Biflavonoids; Catechin; Cinnamomum zeylanicum; Disease Models, Animal; Histamine; Immunoglobulin E; Male; Mice; Mice, Inbred BALB C; Ovalbumin; Plant Bark; Plant Extracts; Polyphenols; Proanthocyanidins; Rhinitis, Allergic; Sneezing

2015
Green tea polyphenol treatment is chondroprotective, anti-inflammatory and palliative in a mouse post-traumatic osteoarthritis model.
    Arthritis research & therapy, 2014, Dec-17, Volume: 16, Issue:6

    Topics: Animals; Anti-Inflammatory Agents; Cartilage, Articular; Catechin; Chondrocytes; Disease Models, Animal; Male; Mice; Mice, Inbred C57BL; Osteoarthritis; Palliative Care; Polyphenols; Tea

2014
Hippocampal Neuroprotection by Minocycline and Epigallo-Catechin-3-Gallate Against Cardiopulmonary Bypass-Associated Injury.
    Brain pathology (Zurich, Switzerland), 2015, Volume: 25, Issue:6

    Topics: Adenosine Triphosphate; Animals; Apoptosis Inducing Factor; Brain Edema; CA1 Region, Hippocampal; CA3 Region, Hippocampal; Cardiopulmonary Bypass; Caspase 3; Catechin; Chromatography, High Pressure Liquid; Disease Models, Animal; Hypoxia-Inducible Factor 1, alpha Subunit; Minocycline; Neuroprotective Agents; Poly Adenosine Diphosphate Ribose; Swine; Tyrosine

2015
Epigallocatechin-3-Gallate Attenuates Oxidative Stress and Inflammation in Obstructive Nephropathy via NF-κB and Nrf2/HO-1 Signalling Pathway Regulation.
    Basic & clinical pharmacology & toxicology, 2015, Volume: 117, Issue:3

    Topics: Animals; Bilirubin; Catechin; Disease Models, Animal; Electrophoretic Mobility Shift Assay; Heme Oxygenase-1; Inflammation; Kidney; Male; Membrane Proteins; Mice; Mice, Inbred C57BL; NF-E2-Related Factor 2; NF-kappa B; Oxidative Stress; Signal Transduction; Ureteral Obstruction

2015
(-) Epigallocatechin-3-gallate attenuates reserpine-induced orofacial dyskinesia and oxidative stress in rat striatum.
    Pharmacology, biochemistry, and behavior, 2015, Volume: 131

    Topics: Animals; Catalase; Catechin; Corpus Striatum; Disease Models, Animal; Glutathione; Lipid Peroxidation; Male; Movement Disorders; Oxidative Stress; Rats; Rats, Wistar; Reserpine; Superoxide Dismutase

2015
Epigallocatechin-3-gallate protects against cisplatin-induced nephrotoxicity by inhibiting endoplasmic reticulum stress-induced apoptosis.
    Experimental biology and medicine (Maywood, N.J.), 2015, Volume: 240, Issue:11

    Topics: Animals; Anti-Inflammatory Agents; Antineoplastic Agents; Antioxidants; Apoptosis; Caspase 12; Catechin; Cisplatin; Disease Models, Animal; Endoplasmic Reticulum Chaperone BiP; Endoplasmic Reticulum Stress; Extracellular Signal-Regulated MAP Kinases; Heat-Shock Proteins; Kidney; Male; Mice; Mice, Inbred C57BL; Phosphorylation

2015
Effect of epigallocatechin gallate on uncoupling protein 2 in acute liver injury.
    International journal of clinical and experimental pathology, 2015, Volume: 8, Issue:1

    Topics: Animals; Antioxidants; Catechin; Chemical and Drug Induced Liver Injury; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Ion Channels; Male; Mitochondrial Proteins; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; Thioacetamide; Uncoupling Protein 2

2015
Anti-atherosclerotic activity of catechins depends on their stereoisomerism.
    Atherosclerosis, 2015, Volume: 240, Issue:1

    Topics: Animals; Aorta; Aortic Diseases; Apolipoproteins E; Atherosclerosis; Biomarkers; Catechin; Cholesterol, HDL; Disease Models, Animal; Hypolipidemic Agents; Male; Mice, Knockout; Molecular Structure; Stereoisomerism; Structure-Activity Relationship; Thiobarbituric Acid Reactive Substances; Triglycerides; Weight Gain

2015
Epigallocatechin-3-gallate attenuates lipopolysaccharide-induced mastitis in rats via suppressing MAPK mediated inflammatory responses and oxidative stress.
    International immunopharmacology, 2015, Volume: 26, Issue:1

    Topics: Animals; Blotting, Western; Catechin; Disease Models, Animal; Female; Lipopolysaccharides; Male; Mammary Glands, Animal; Mastitis; Mitogen-Activated Protein Kinase Kinases; Oxidative Stress; Pregnancy; Rats, Sprague-Dawley

2015
Epigallocatechin gallate stimulates the neuroreactive salivary secretomotor system in autoimmune sialadenitis of MRL-Fas(lpr) mice via activation of cAMP-dependent protein kinase A and inactivation of nuclear factor κB.
    Autoimmunity, 2015, Volume: 48, Issue:6

    Topics: Animals; Aquaporin 5; Autoimmune Diseases; Catechin; Cyclic AMP-Dependent Protein Kinases; Disease Models, Animal; Gene Expression Regulation; Histone Deacetylase 1; Immunohistochemistry; JNK Mitogen-Activated Protein Kinases; Mice; Mice, Inbred MRL lpr; NF-kappa B; Protein Subunits; Reactive Oxygen Species; Salivary Glands; Sialadenitis; Submandibular Gland

2015
[Efficacy of epigallocatechin gallate in treatment of alkali burn injury of murine cornea].
    Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences, 2015, Volume: 44, Issue:1

    Topics: Alkalies; Animals; Burns, Chemical; Catechin; Cornea; Corneal Neovascularization; Disease Models, Animal; Eye Burns; Inflammation; Mice; Mice, Inbred C57BL; Neutrophils; RNA, Messenger; Vascular Endothelial Growth Factor A

2015
[Anti-Candida activity of aroma candy and its protective activity against murine oral candidiasis].
    Medical mycology journal, 2015, Volume: 56, Issue:1

    Topics: Acyclic Monoterpenes; Animals; Candida albicans; Candidiasis, Oral; Candy; Cassia; Catechin; Codonopsis; Decanoic Acids; Disease Models, Animal; Drug Combinations; Drug Resistance, Fungal; Fatty Acids; Glycyrrhiza; Maltose; Mice; Mice, Inbred ICR; Monoterpenes; Phenols; Plant Extracts; Polyphenols; Propolis; Specific Pathogen-Free Organisms; Starch; Sugar Alcohols; Treatment Outcome

2015
(-)-Epigallocatechin-3-gallate attenuates cognitive deterioration in Alzheimer's disease model mice by upregulating neprilysin expression.
    Experimental cell research, 2015, May-15, Volume: 334, Issue:1

    Topics: Alzheimer Disease; Animals; Catechin; Cell Proliferation; Cells, Cultured; CHO Cells; Cognition Disorders; Cricetulus; Disease Models, Animal; Mice; Neprilysin; Stereoisomerism; Up-Regulation

2015
Green tea polyphenol epigallocatechin-3-gallate ameliorates insulin resistance in non-alcoholic fatty liver disease mice.
    Acta pharmacologica Sinica, 2015, Volume: 36, Issue:5

    Topics: Animals; Biomarkers; Blood Glucose; Camellia sinensis; Catechin; Diet, High-Fat; Disease Models, Animal; Dose-Response Relationship, Drug; Hypoglycemic Agents; Insulin; Insulin Resistance; Insulysin; Liver; Male; Mice, Inbred C57BL; Non-alcoholic Fatty Liver Disease; Phytotherapy; Plants, Medicinal; Time Factors

2015
Epigallocatechin 3-gallate ameliorates bile duct ligation induced liver injury in mice by modulation of mitochondrial oxidative stress and inflammation.
    PloS one, 2015, Volume: 10, Issue:5

    Topics: Animals; Bile Ducts, Intrahepatic; Catechin; Cell Death; Cholestasis; Cytokines; Disease Models, Animal; Gene Expression Regulation; Hepatic Stellate Cells; Hepatocytes; Inflammation; Liver Cirrhosis; Mice; Mitochondria; NF-kappa B; Oxidative Stress

2015
Epigallocatechin gallate attenuated non-alcoholic steatohepatitis induced by methionine- and choline-deficient diet.
    European journal of pharmacology, 2015, Aug-15, Volume: 761

    Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Biomarkers; Catechin; Choline Deficiency; Cytoprotection; Disease Models, Animal; Dose-Response Relationship, Drug; Hep G2 Cells; Humans; Inflammation Mediators; Lipids; Liver; Male; Methionine; Mice, Inbred C57BL; Non-alcoholic Fatty Liver Disease; Oxidative Stress; Signal Transduction; Transforming Growth Factor beta

2015
Nodulisporiviridins A-H, Bioactive Viridins from Nodulisporium sp.
    Journal of natural products, 2015, Jun-26, Volume: 78, Issue:6

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Androstenes; Animals; Bacteriocins; Catechin; China; Crystallography, X-Ray; Disease Models, Animal; Humans; Molecular Conformation; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Peptide Fragments; Xylariales

2015
Biochemical and histopathological effects of catechin on experimental peripheral nerve injuries.
    Turkish neurosurgery, 2015, Volume: 25, Issue:3

    Topics: Animals; Catechin; Disease Models, Animal; Male; Neuroprotective Agents; Peripheral Nerve Injuries; Rats; Rats, Wistar

2015
Protective effects of epigallocatechin-3-gallate on intestinal ischemia reperfusion injury through enhanced activation of PI3K/Akt pathway in rats.
    Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban, 2015, Volume: 35, Issue:3

    Topics: Animals; Anti-Inflammatory Agents; Catechin; Disease Models, Animal; Gene Expression Regulation; Interleukin-1; Interleukin-6; Intestines; Male; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Rats; Rats, Wistar; Reperfusion Injury; Signal Transduction; Tumor Necrosis Factor-alpha

2015
Paraventricular Nucleus Infusion of Epigallocatechin-3-O-Gallate Improves Renovascular Hypertension.
    Cardiovascular toxicology, 2016, Volume: 16, Issue:3

    Topics: Animals; Anti-Inflammatory Agents; Antihypertensive Agents; Antioxidants; Blood Pressure; Catechin; Cytokines; Disease Models, Animal; Hypertension, Renovascular; Infusions, Parenteral; Male; Membrane Glycoproteins; NADPH Oxidase 2; NADPH Oxidase 4; NADPH Oxidases; Oxidative Stress; Paraventricular Hypothalamic Nucleus; Rats, Sprague-Dawley; Superoxide Dismutase-1; Time Factors

2016
Rescue of the abnormal skeletal phenotype in Ts65Dn Down syndrome mice using genetic and therapeutic modulation of trisomic Dyrk1a.
    Human molecular genetics, 2015, Oct-15, Volume: 24, Issue:20

    Topics: Animals; Bone Diseases; Catechin; Disease Models, Animal; Down Syndrome; Dyrk Kinases; Gene Dosage; Male; Mice; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases

2015
Procyanidin B2 attenuates neurological deficits and blood-brain barrier disruption in a rat model of cerebral ischemia.
    Molecular nutrition & food research, 2015, Volume: 59, Issue:10

    Topics: Animals; Biflavonoids; Blood-Brain Barrier; Brain Edema; Brain Ischemia; Catechin; Disease Models, Animal; Glutathione Transferase; Heme Oxygenase-1; Inactivation, Metabolic; Infarction, Middle Cerebral Artery; Isoenzymes; Male; NAD(P)H Dehydrogenase (Quinone); Neuroprotective Agents; Oxidative Stress; Permeability; Proanthocyanidins; Rats, Sprague-Dawley; Tight Junctions

2015
Protective Effects of Catechin against Monosodium Urate-Induced Inflammation through the Modulation of NLRP3 Inflammasome Activation.
    Journal of agricultural and food chemistry, 2015, Aug-26, Volume: 63, Issue:33

    Topics: Animals; Calcium; Carrier Proteins; Catechin; Disease Models, Animal; Free Radical Scavengers; Gallic Acid; Inflammasomes; Inflammation; Interleukin-1beta; Male; Mice, Inbred C57BL; NLR Family, Pyrin Domain-Containing 3 Protein; Oxidative Stress; Peritonitis; Protective Agents; Uric Acid

2015
[Study on inhibitory effect of EGCG on Calcium oxalate nephrolithiasis in rats and its related mechanism].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2015, Volume: 40, Issue:7

    Topics: Animals; Blood Urea Nitrogen; Calcium; Calcium Oxalate; Catechin; Creatinine; Disease Models, Animal; Humans; Kidney; Male; Nephrolithiasis; Osteopontin; Rats; Rats, Wistar

2015
EGCG induces G-CSF expression and neutrophilia in experimental sepsis.
    Immunologic research, 2015, Volume: 63, Issue:1-3

    Topics: Animals; Anti-Inflammatory Agents; Catechin; Cells, Cultured; Chemokines; Disease Models, Animal; Granulocyte Colony-Stimulating Factor; HMGB1 Protein; Humans; Leukocytes, Mononuclear; Macrophages, Peritoneal; Male; Mice; Mice, Inbred BALB C; Neutrophils; Sepsis; Tea

2015
Epicatechin Reduces Striatal MPP⁺-Induced Damage in Rats through Slight Increases in SOD-Cu,Zn Activity.
    Oxidative medicine and cellular longevity, 2015, Volume: 2015

    Topics: 1-Methyl-4-phenylpyridinium; Animals; Catechin; Copper; Disease Models, Animal; Male; Rats; Rats, Wistar; Zinc

2015
Prevention of hepatitis C virus infection using a broad cross-neutralizing monoclonal antibody (AR4A) and epigallocatechin gallate.
    Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society, 2016, Volume: 22, Issue:3

    Topics: Animals; Antibodies, Monoclonal; Antibodies, Neutralizing; Antiviral Agents; Broadly Neutralizing Antibodies; Catechin; Cell Line; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Therapy, Combination; Genotype; Hepatitis C; Hepatitis Viruses; Humans; Liver; Mice, SCID; Time Factors

2016
QIAD assay for quantitating a compound's efficacy in elimination of toxic Aβ oligomers.
    Scientific reports, 2015, Sep-23, Volume: 5

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Carrier Proteins; Catechin; Disease Models, Animal; Ferredoxin-NADP Reductase; Humans; Inositol; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Mice, Transgenic; Oligopeptides; Protein Aggregation, Pathological; Taurine

2015
Dressing with epigallocatechin gallate nanoparticles for wound regeneration.
    Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society, 2016, Volume: 24, Issue:2

    Topics: Animals; Anti-Bacterial Agents; Bandages; Biocompatible Materials; Catechin; Cells, Cultured; Chitosan; Disease Models, Animal; Drug Delivery Systems; Fibroblasts; Gelatin; Gentamicins; Humans; Hydrogel, Polyethylene Glycol Dimethacrylate; Male; Materials Testing; Nanoparticles; Polyglutamic Acid; Rats; Rats, Sprague-Dawley; Re-Epithelialization; Wound Healing; Wounds and Injuries

2016
Regulation of Transforming Growth Factor β-Activated Kinase Activation by Epigallocatechin-3-Gallate in Rheumatoid Arthritis Synovial Fibroblasts: Suppression of K(63) -Linked Autoubiquitination of Tumor Necrosis Factor Receptor-Associated Factor 6.
    Arthritis & rheumatology (Hoboken, N.J.), 2016, Volume: 68, Issue:2

    Topics: Animals; Anti-Inflammatory Agents; Arthritis, Experimental; Arthritis, Rheumatoid; Blotting, Western; Catechin; Disease Models, Animal; Female; Fibroblasts; Humans; Immunoprecipitation; In Vitro Techniques; Interleukin-1 Receptor-Associated Kinases; Interleukin-1beta; Interleukin-6; Interleukin-8; Lysine; MAP Kinase Kinase Kinases; Molecular Docking Simulation; Proteasome Endopeptidase Complex; Protein Processing, Post-Translational; Rats; Rats, Inbred Lew; Synovial Membrane; TNF Receptor-Associated Factor 6; Ubiquitination

2016
Green tea inhibited the elimination of nephro-cardiovascular toxins and deteriorated the renal function in rats with renal failure.
    Scientific reports, 2015, Nov-10, Volume: 5

    Topics: Adenine; Animals; Catechin; CHO Cells; Creatinine; Cresols; Cricetinae; Cricetulus; Disease Models, Animal; Glucuronides; HEK293 Cells; Humans; Indican; Kidney; Male; Organic Anion Transport Protein 1; Organic Anion Transporters, Sodium-Independent; Rats; Rats, Sprague-Dawley; Renal Insufficiency; Sulfates; Sulfuric Acid Esters; Tea; Toxins, Biological

2015
Green Tea Polyphenol Prevents Diabetic Rats From Acute Kidney Injury After Cardiopulmonary Bypass.
    The Annals of thoracic surgery, 2016, Volume: 101, Issue:4

    Topics: Acute Kidney Injury; Administration, Oral; Animals; Biopsy, Needle; Cardiopulmonary Bypass; Catechin; Diabetes Mellitus, Experimental; Disease Models, Animal; Follow-Up Studies; Immunohistochemistry; Kidney Function Tests; Male; Polyphenols; Preoperative Care; Random Allocation; Rats; Rats, Wistar; Real-Time Polymerase Chain Reaction; Reference Values; Risk Assessment; Tea; Treatment Outcome

2016
Differential effects of Epigallocatechin-3-gallate containing supplements on correcting skeletal defects in a Down syndrome mouse model.
    Molecular nutrition & food research, 2016, Volume: 60, Issue:4

    Topics: Absorptiometry, Photon; Animals; Bone and Bones; Catechin; Dietary Supplements; Disease Models, Animal; Down Syndrome; Female; Femur; Male; Mice, Inbred C57BL; Mice, Mutant Strains; X-Ray Microtomography

2016
Epigallocatechin Gallate Extends the Therapeutic Window of Recombinant Tissue Plasminogen Activator Treatment in Ischemic Rats.
    Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association, 2016, Volume: 25, Issue:4

    Topics: Animals; Blood-Brain Barrier; Brain Edema; Catechin; Disease Models, Animal; Drug Therapy, Combination; Fibrinolytic Agents; Gene Expression Regulation; Infarction, Middle Cerebral Artery; Male; Matrix Metalloproteinase 1; Matrix Metalloproteinase 9; Neuroprotective Agents; Permeability; Plasminogen Activator Inhibitor 1; Rats; Rats, Sprague-Dawley; Sensory Gating; Time Factors; Tissue Plasminogen Activator; Treatment Outcome

2016
The Effect of Epigallocatechin Gallate on Flap Viability of Rat Perforator Abdominal Flaps.
    Journal of reconstructive microsurgery, 2016, Volume: 32, Issue:4

    Topics: Abdomen; Angiogenesis Inducing Agents; Animals; Catechin; Disease Models, Animal; Female; Graft Survival; Perforator Flap; Plastic Surgery Procedures; Rats; Rats, Wistar; Regional Blood Flow

2016
Nitric oxide pathway activity modulation alters the protective effects of (-)Epigallocatechin-3-gallate on reserpine-induced impairment in rats.
    Behavioural brain research, 2016, May-15, Volume: 305

    Topics: Animals; Arginine; Catechin; Discrimination, Psychological; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Exploratory Behavior; Glutathione; Hippocampus; Lipid Peroxidation; Male; Memory Disorders; Neuroprotective Agents; NG-Nitroarginine Methyl Ester; Nitric Oxide; Rats; Rats, Wistar; Reserpine; Signal Transduction; Smell; Superoxide Dismutase

2016
Epigallocatechin-3-gallate ameliorates autoimmune arthritis by reciprocal regulation of T helper-17 regulatory T cells and inhibition of osteoclastogenesis by inhibiting STAT3 signaling.
    Journal of leukocyte biology, 2016, Volume: 100, Issue:3

    Topics: Animals; Antioxidants; Arthritis, Experimental; Autoimmune Diseases; Catechin; Cell Differentiation; Cells, Cultured; Disease Models, Animal; Male; Mice; Mice, Inbred DBA; Mice, Knockout; Osteoclasts; Osteogenesis; Signal Transduction; STAT3 Transcription Factor; T-Lymphocytes, Regulatory; Th17 Cells

2016
The polyphenols resveratrol and epigallocatechin-3-gallate restore the severe impairment of mitochondria in hippocampal progenitor cells from a Down syndrome mouse model.
    Biochimica et biophysica acta, 2016, Volume: 1862, Issue:6

    Topics: Adenosine Triphosphate; AMP-Activated Protein Kinase Kinases; Animals; Antioxidants; Catechin; Cell Proliferation; Cells, Cultured; Disease Models, Animal; Down Syndrome; Female; Hippocampus; Male; Mice; Mitochondria; Neural Stem Cells; Neurogenesis; Neuroprotective Agents; Protein Kinases; Resveratrol

2016
Epigallocatechin-3-Gallate Inhibition of Myeloperoxidase and Its Counter-Regulation by Dietary Iron and Lipocalin 2 in Murine Model of Gut Inflammation.
    The American journal of pathology, 2016, Volume: 186, Issue:4

    Topics: Acute-Phase Proteins; Animals; Antioxidants; Catechin; Dextran Sulfate; Disease Models, Animal; Humans; Inflammation; Iron, Dietary; Lipocalin-2; Lipocalins; Mice, Inbred C57BL; Oncogene Proteins; Peroxidase; Proto-Oncogene Proteins; Tea

2016
(-)-Epicatechin-induced recovery of mitochondria from simulated diabetes: Potential role of endothelial nitric oxide synthase.
    Diabetes & vascular disease research, 2016, Volume: 13, Issue:3

    Topics: Animals; Catechin; Cells, Cultured; Diabetes Mellitus, Type 2; Diet, High-Fat; Disease Models, Animal; Endothelial Cells; Enzyme Inhibitors; Humans; Mice, Inbred C57BL; Mitochondria, Heart; Myocardium; Nitric Oxide; Nitric Oxide Synthase Type III; Organelle Biogenesis; Phosphorylation; RNA Interference; Signal Transduction; Transfection

2016
Neurorestorative effects of epigallocatechin-3-Gallate on cognitive function in a chronic cerebral hypoperfusion rat model.
    Restorative neurology and neuroscience, 2016, 04-11, Volume: 34, Issue:3

    Topics: Animals; Brain-Derived Neurotrophic Factor; Catechin; Cerebrovascular Disorders; Cognition Disorders; Disease Models, Animal; Drug Administration Routes; Escape Reaction; Hippocampus; Male; Malondialdehyde; Maze Learning; Neuroprotective Agents; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Superoxide Dismutase; Vascular Endothelial Growth Factor A

2016
(-)-Epigallocatechin-3-gallate decreases colonic inflammation and permeability in a mouse model of colitis, but reduces macronutrient digestion and exacerbates weight loss.
    Molecular nutrition & food research, 2016, Volume: 60, Issue:10

    Topics: Animals; Biomarkers; Caco-2 Cells; Catechin; Chemokine CCL2; Colitis, Ulcerative; Dextran Sulfate; Digestion; Disease Models, Animal; Humans; Intestinal Absorption; Male; Mice, Inbred Strains; Oxidative Stress; Permeability; Weight Loss

2016
Epigallocatechin gallate exerts protective effects against myocardial ischemia/reperfusion injury through the PI3K/Akt pathway-mediated inhibition of apoptosis and the restoration of the autophagic flux.
    International journal of molecular medicine, 2016, Volume: 38, Issue:1

    Topics: Animals; Apoptosis; Autophagy; Cardiotonic Agents; Catechin; Creatine Kinase, MB Form; Disease Models, Animal; Hemodynamics; L-Lactate Dehydrogenase; Male; Myocardial Reperfusion Injury; Myocardium; Nitric Oxide; Nitric Oxide Synthase Type III; Phosphatidylinositol 3-Kinases; Phosphorylation; Proto-Oncogene Proteins c-akt; Rats, Sprague-Dawley; TOR Serine-Threonine Kinases

2016
Strong Inhibition of Secretory Sphingomyelinase by Catechins, Particularly by (-)-Epicatechin 3-O-Gallate and (-)-3'-O-Methylepigallocatechin 3-O-Gallate.
    Journal of nutritional science and vitaminology, 2016, Volume: 62, Issue:2

    Topics: Animals; Atherosclerosis; Catechin; Diabetes Mellitus, Type 2; Disease Models, Animal; Hydrogen-Ion Concentration; Male; Oxidative Stress; Rats; Rats, Sprague-Dawley; Sphingomyelin Phosphodiesterase

2016
Chemical composition and anti-inflammatory activity of the leaves of Byrsonima verbascifolia.
    Journal of natural medicines, 2016, Volume: 70, Issue:4

    Topics: Animals; Anti-Inflammatory Agents; Brazil; Catechin; Disease Models, Animal; Edema; Female; Flavonoids; Glycosides; Inflammation; Lipopolysaccharides; Macrophages; Male; Malpighiaceae; Mice, Inbred BALB C; Mice, Inbred Strains; Nitric Oxide; Phytotherapy; Plant Extracts; Plant Leaves; Triterpenes

2016
Synergistic Effect of Artificial Tears Containing Epigallocatechin Gallate and Hyaluronic Acid for the Treatment of Rabbits with Dry Eye Syndrome.
    PloS one, 2016, Volume: 11, Issue:6

    Topics: Animals; Catechin; Cytokines; Disease Models, Animal; Drug Synergism; Dry Eye Syndromes; Epithelial Cells; Epithelium, Corneal; Gene Expression Profiling; Humans; Hyaluronic Acid; Inflammation Mediators; Lubricant Eye Drops; Male; Rabbits

2016
Protective potential of epigallocatechin-3-gallate against benign prostatic hyperplasia in metabolic syndrome rats.
    Environmental toxicology and pharmacology, 2016, Volume: 45

    Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Catechin; Cytokines; Disease Models, Animal; Male; Metabolic Syndrome; Oxidative Stress; Peroxisome Proliferator-Activated Receptors; Prostatic Hyperplasia; Rats, Sprague-Dawley; Somatomedins

2016
EGCG Suppresses ERK5 Activation to Reverse Tobacco Smoke-Triggered Gastric Epithelial-Mesenchymal Transition in BALB/c Mice.
    Nutrients, 2016, Jul-20, Volume: 8, Issue:7

    Topics: Animals; Anticarcinogenic Agents; Benzodiazepinones; Biomarkers, Tumor; Carcinogenesis; Catechin; Dietary Supplements; Disease Models, Animal; Enzyme Activation; Epithelial-Mesenchymal Transition; Gastric Mucosa; Gene Expression Regulation, Neoplastic; Injections, Intraperitoneal; Mice; Mice, Inbred BALB C; Mitogen-Activated Protein Kinase 7; Phosphorylation; Protein Kinase Inhibitors; Protein Processing, Post-Translational; Random Allocation; Smoking; Stomach Neoplasms

2016
Short- and long-term effects of neonatal pharmacotherapy with epigallocatechin-3-gallate on hippocampal development in the Ts65Dn mouse model of Down syndrome.
    Neuroscience, 2016, 10-01, Volume: 333

    Topics: Animals; Catechin; Cognition; Disease Models, Animal; Down Syndrome; Female; Hippocampus; Male; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Transgenic; Neocortex; Neural Pathways; Neurogenesis; Neuroprotective Agents; Synapses; Time Factors

2016
Green tea (-)-epigallocatechin-3-gallate counteracts daytime overeating induced by high-fat diet in mice.
    Molecular nutrition & food research, 2016, Volume: 60, Issue:12

    Topics: Animals; Antioxidants; Catechin; Diet, High-Fat; Disease Models, Animal; Feeding Behavior; Homeostasis; Hyperphagia; Hypothalamus; Male; Mice; Mice, Inbred C57BL; Mice, Obese; Obesity; Tea

2016
Prevention of abdominal aortic aneurysm progression by oral administration of green tea polyphenol in a rat model.
    Journal of vascular surgery, 2017, Volume: 65, Issue:6

    Topics: Administration, Oral; Animals; Anti-Inflammatory Agents; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Calcium Chloride; Catechin; Collagen; Cytokines; Dilatation, Pathologic; Disease Models, Animal; Disease Progression; Elastin; Gene Expression Regulation; Inflammation Mediators; Male; Matrix Metalloproteinase 1; Matrix Metalloproteinase 9; Pancreatic Elastase; Phytotherapy; Plant Extracts; Plants, Medicinal; Polyphenols; Protein-Lysine 6-Oxidase; Rats, Sprague-Dawley; Tea; Time Factors; Tropoelastin

2017
Procyanidin Promotes Translocation of Glucose Transporter 4 in Muscle of Mice through Activation of Insulin and AMPK Signaling Pathways.
    PloS one, 2016, Volume: 11, Issue:9

    Topics: AMP-Activated Protein Kinases; Animals; Anthocyanins; Biflavonoids; Catechin; Disease Models, Animal; Glucose; Glucose Transporter Type 4; Glucosides; Humans; Hyperglycemia; Insulin; Mice; Muscle, Skeletal; Proanthocyanidins; Signal Transduction

2016
Olive and grape seed extract prevents post-traumatic osteoarthritis damages and exhibits in vitro anti IL-1β activities before and after oral consumption.
    Scientific reports, 2016, 09-19, Volume: 6

    Topics: Administration, Oral; Animals; Anterior Cruciate Ligament; Biflavonoids; Catechin; Cyclooxygenase 2; Diet; Dinoprostone; Disease Models, Animal; Female; Grape Seed Extract; Interleukin-1beta; Male; Mass Spectrometry; Matrix Metalloproteinase 13; Metabolome; Mice, Inbred C57BL; Nitric Oxide; Nitric Oxide Synthase Type II; Olea; Osteoarthritis; Phenylethyl Alcohol; Proanthocyanidins; Rabbits; RNA, Messenger; Wounds and Injuries

2016
Epigallocatechin-3-gallate Attenuates Renal Damage by Suppressing Oxidative Stress in Diabetic db/db Mice.
    Oxidative medicine and cellular longevity, 2016, Volume: 2016

    Topics: Animals; Catechin; Diabetes Insipidus, Nephrogenic; Disease Models, Animal; Kidney; Mice; Mice, Inbred C57BL; Oxidative Stress

2016
Restoration of Mimecan Expression by Grape Seed Procyanidin B2 Through Regulation of Nuclear Factor-kappaB in Mice With Diabetic Nephropathy.
    Iranian journal of kidney diseases, 2016, Volume: 10, Issue:5

    Topics: Albuminuria; Animals; Biflavonoids; Blotting, Western; Body Weight; Catechin; Cholesterol; Diabetes Mellitus; Diabetic Nephropathies; Disease Models, Animal; Glomerular Basement Membrane; Glycation End Products, Advanced; Grape Seed Extract; Intercellular Signaling Peptides and Proteins; Kidney Glomerulus; Mesangial Cells; Mice; NF-kappa B; Oxidative Stress; Proanthocyanidins; Triglycerides

2016
Epigallocatechin-3-gallate protects against hepatic ischaemia-reperfusion injury by reducing oxidative stress and apoptotic cell death.
    The Journal of international medical research, 2016, Volume: 44, Issue:6

    Topics: Animals; Antioxidants; Apoptosis; bcl-2-Associated X Protein; Caspase 3; Caspase 9; Catechin; Cytochromes c; Disease Models, Animal; Glutathione; Glutathione Disulfide; Inflammation; Injections, Intraperitoneal; Lipid Peroxidation; Liver; Male; Mice; Mice, Inbred C57BL; Oxidative Stress; Proto-Oncogene Proteins c-bcl-2; Reperfusion Injury

2016
Procyanidins Mitigate Osteoarthritis Pathogenesis by, at Least in Part, Suppressing Vascular Endothelial Growth Factor Signaling.
    International journal of molecular sciences, 2016, Dec-09, Volume: 17, Issue:12

    Topics: Animals; Biflavonoids; Catechin; Cells, Cultured; Chondrocytes; Collagen Type II; Disease Models, Animal; Female; Humans; Immunohistochemistry; Male; Mice; Middle Aged; Osteoarthritis; Osteoporosis; Proanthocyanidins; Signal Transduction; Vascular Endothelial Growth Factor A

2016
Epigallocatechin-3-gallate promotes angiogenesis via up-regulation of Nfr2 signaling pathway in a mouse model of ischemic stroke.
    Behavioural brain research, 2017, 03-15, Volume: 321

    Topics: Angiogenesis Inducing Agents; Animals; Brain; Catechin; Disease Models, Animal; Flavonoids; Infarction, Middle Cerebral Artery; Male; Mice, Inbred C57BL; Neovascularization, Physiologic; Neuroprotective Agents; NF-E2-Related Factor 2; Oxidative Stress; Protein Kinase Inhibitors; Random Allocation; Signal Transduction; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor Receptor-2

2017
Epicatechin downregulates adipose tissue CCL19 expression and thereby ameliorates diet-induced obesity and insulin resistance.
    Nutrition, metabolism, and cardiovascular diseases : NMCD, 2017, Volume: 27, Issue:3

    Topics: 3T3-L1 Cells; Adipocytes; Adipose Tissue; Animals; Anti-Inflammatory Agents; Catechin; Chemokine CCL19; Coculture Techniques; Diet, High-Fat; Disease Models, Animal; Down-Regulation; Insulin Resistance; Macrophage Activation; Macrophages; Mice; Mice, Inbred C57BL; Obesity; Panniculitis; RAW 264.7 Cells; Time Factors

2017
The Green Tea Catechin Epigallocatechin Gallate Ameliorates Graft-versus-Host Disease.
    PloS one, 2017, Volume: 12, Issue:1

    Topics: Alkaloids; Allografts; Animals; Antioxidants; Benzodioxoles; Catechin; Disease Models, Animal; Female; Graft Survival; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans; Immunologic Factors; Male; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Neovascularization, Pathologic; Oxidative Stress; Piperidines; Polyunsaturated Alkamides; Quercetin; T-Lymphocytes, Regulatory; Tea

2017
Preparation of arginine-glycine-aspartic acid-modified biopolymeric nanoparticles containing epigalloccatechin-3-gallate for targeting vascular endothelial cells to inhibit corneal neovascularization.
    International journal of nanomedicine, 2017, Volume: 12

    Topics: Angiogenesis Inhibitors; Animals; Burns, Chemical; Catechin; Cell Survival; Corneal Neovascularization; Disease Models, Animal; Eye Burns; Human Umbilical Vein Endothelial Cells; Humans; Hyaluronic Acid; Integrin alphaVbeta3; Mice, Inbred C57BL; Molecular Targeted Therapy; Nanoparticles; Oligopeptides; Ophthalmic Solutions

2017
Targeted nanoparticles encapsulating (-)-epigallocatechin-3-gallate for prostate cancer prevention and therapy.
    Scientific reports, 2017, 02-01, Volume: 7

    Topics: Animals; Anticarcinogenic Agents; Apoptosis; Catechin; Cell Line, Tumor; Cell Proliferation; Cell Survival; Disease Models, Animal; Drug Carriers; Drug Compounding; Drug Liberation; Humans; Kinetics; Ligands; Male; Mice; Molecular Conformation; Molecular Targeted Therapy; Nanoparticles; Particle Size; Polyesters; Polyethylene Glycols; Prostatic Neoplasms; Tumor Burden; Xenograft Model Antitumor Assays

2017
Influence of prenatal EGCG treatment and Dyrk1a dosage reduction on craniofacial features associated with Down syndrome.
    Human molecular genetics, 2016, 11-15, Volume: 25, Issue:22

    Topics: Animals; Catechin; Craniofacial Abnormalities; Disease Models, Animal; Down Syndrome; Dyrk Kinases; Female; Gene Dosage; Mice; Phenotype; Phosphorylation; Pregnancy; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases

2016
Regression of atherosclerosis with apple procyanidins by activating the ATP-binding cassette subfamily A member 1 in a rabbit model.
    Atherosclerosis, 2017, Volume: 258

    Topics: Animals; Aorta; Aortic Diseases; Atherosclerosis; ATP Binding Cassette Transporter 1; Biflavonoids; Cardiovascular Agents; Catechin; Cholesterol; Disease Models, Animal; Fruit; Lipoproteins, LDL; Male; Malus; Oxidative Stress; Phytotherapy; Plants, Medicinal; Plaque, Atherosclerotic; Proanthocyanidins; Reactive Oxygen Species; RNA, Messenger; Scavenger Receptors, Class E; Time Factors; Up-Regulation

2017
Effects of COX1-2/5-LOX blockade in Alzheimer transgenic 3xTg-AD mice.
    Inflammation research : official journal of the European Histamine Research Society ... [et al.], 2017, Volume: 66, Issue:5

    Topics: Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Brain; Catechin; Cyclooxygenase Inhibitors; Dinoprostone; Disease Models, Animal; Drug Combinations; Interleukin-1beta; Leukotriene B4; Lipoxygenase Inhibitors; Male; Maze Learning; Memory; Mice, Transgenic; Neuroprotective Agents; NLR Family, Pyrin Domain-Containing 3 Protein; tau Proteins

2017
A green tea component suppresses posttranslational expression of basic fibroblast growth factor in colorectal cancer.
    Gastroenterology, 2008, Volume: 134, Issue:7

    Topics: Acetylcysteine; Adenomatous Polyposis Coli; Animals; Antineoplastic Agents, Phytogenic; Camellia sinensis; Catechin; Cell Transformation, Neoplastic; Colorectal Neoplasms; Cycloheximide; Cysteine Proteinase Inhibitors; Disease Models, Animal; Dose-Response Relationship, Drug; Down-Regulation; Fibroblast Growth Factor 2; Genes, APC; HCT116 Cells; HT29 Cells; Humans; Mice; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Protein Processing, Post-Translational; Protein Synthesis Inhibitors; Time Factors; Transfection

2008
Short- and long-term effects of (-)-epicatechin on myocardial ischemia-reperfusion injury.
    American journal of physiology. Heart and circulatory physiology, 2008, Volume: 295, Issue:2

    Topics: Administration, Oral; Animals; Cardiovascular Agents; Catechin; Disease Models, Animal; Drug Administration Schedule; Hemodynamics; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Myocardial Infarction; Myocardial Reperfusion Injury; Myocardium; Oxidative Stress; Peroxidase; Rats; Rats, Sprague-Dawley; Time Factors

2008
(-)-Epigallocatechin-3-gallate suppresses osteoclast differentiation and ameliorates experimental arthritis in mice.
    Arthritis and rheumatism, 2008, Volume: 58, Issue:7

    Topics: Animals; Antimutagenic Agents; Arthritis; Blotting, Western; Catechin; Cell Differentiation; Disease Models, Animal; Down-Regulation; Gene Expression; Humans; Mice; NF-kappa B; NFATC Transcription Factors; Osteoclasts; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Reverse Transcriptase Polymerase Chain Reaction

2008
Epigallocatechin-3-gallate inhibits IL-6 synthesis and suppresses transsignaling by enhancing soluble gp130 production.
    Proceedings of the National Academy of Sciences of the United States of America, 2008, Sep-23, Volume: 105, Issue:38

    Topics: Animals; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Catechin; Cells, Cultured; Cytokine Receptor gp130; Cytokines; Disease Models, Animal; Female; Fibroblasts; Gene Expression Regulation; Humans; Interleukin-1beta; Interleukin-6; Matrix Metalloproteinase 2; Rats; Rats, Inbred Lew; Receptors, Interleukin-6; Synovial Membrane; Up-Regulation

2008
Effects of oral consumption of the green tea polyphenol EGCG in a murine model for human Sjogren's syndrome, an autoimmune disease.
    Life sciences, 2008, Oct-24, Volume: 83, Issue:17-18

    Topics: Administration, Oral; Animals; Antibodies, Antinuclear; Apoptosis; Catechin; Diabetes Mellitus, Type 1; Disease Models, Animal; Female; Humans; Ki-67 Antigen; Lymphocytes; Mice; Mice, Inbred NOD; Phytotherapy; Proliferating Cell Nuclear Antigen; Sjogren's Syndrome; Submandibular Gland; Tea

2008
Neuroprotective effects of (+/-)-catechin against 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced dopaminergic neurotoxicity in mice.
    Neuroscience letters, 2009, Jan-30, Volume: 450, Issue:2

    Topics: Animals; Catechin; Corpus Striatum; Disease Models, Animal; Dopamine; Dose-Response Relationship, Drug; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; JNK Mitogen-Activated Protein Kinases; Male; Mice; Mice, Inbred C57BL; MPTP Poisoning; Neuroprotective Agents; Serine; Tyrosine 3-Monooxygenase

2009
Chemoprevention of fibroid tumors by [-]-epigallocatechin-3-gallate in quail.
    Nutrition research (New York, N.Y.), 2008, Volume: 28, Issue:2

    Topics: Animals; Anticarcinogenic Agents; Bird Diseases; Catechin; Coturnix; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Humans; Leiomyoma; Oviducts; Random Allocation; Uterine Neoplasms

2008
Anti-angiogenic effects of green tea catechin on an experimental endometriosis mouse model.
    Human reproduction (Oxford, England), 2009, Volume: 24, Issue:3

    Topics: Angiogenesis Inhibitors; Animals; Catechin; Cell Proliferation; Disease Models, Animal; Endometriosis; Endometrium; Female; Humans; Mice; Mice, SCID; Microcirculation; Neovascularization, Pathologic; Tea; Vitamin E

2009
EGCG inhibits proliferation of cardiac fibroblasts in rats with cardiac hypertrophy.
    Planta medica, 2009, Volume: 75, Issue:2

    Topics: Angiotensin II; Animals; Antioxidants; Atrial Natriuretic Factor; Camellia sinensis; Cardiomegaly; Catechin; Cell Proliferation; Disease Models, Animal; DNA-Binding Proteins; Dose-Response Relationship, Drug; Endothelins; Enzyme Inhibitors; Fibroblasts; Fibrosis; Hydroxyproline; Male; Myocardium; Nitric Oxide Synthase Type II; Nitrites; Organ Size; Plant Extracts; Proliferating Cell Nuclear Antigen; Rats; Rats, Sprague-Dawley; Transcription Factors

2009
Catechin reduces atherosclerotic lesion development in apo E-deficient mice: a transcriptomic study.
    Atherosclerosis, 2009, Volume: 204, Issue:2

    Topics: Animals; Antioxidants; Aortic Diseases; Apolipoproteins E; Atherosclerosis; Catechin; Dietary Supplements; Disease Models, Animal; Disease Progression; Gene Expression Profiling; Gene Expression Regulation; Inflammation; Inflammation Mediators; Lipids; Liver; Male; Mice; Mice, Knockout; Oligonucleotide Array Sequence Analysis; Polymerase Chain Reaction; Serum Amyloid A Protein

2009
An extract of green tea, epigallocatechin-3-gallate, reduces periapical lesions by inhibiting cysteine-rich 61 expression in osteoblasts.
    Journal of endodontics, 2009, Volume: 35, Issue:2

    Topics: Alveolar Bone Loss; Animals; Antioxidants; Catechin; Cell Line, Tumor; Chemokine CCL2; Chemotaxis, Leukocyte; Cysteine-Rich Protein 61; Disease Models, Animal; Humans; Oncostatin M; Osteoblasts; Periapical Periodontitis; Plant Extracts; Rats; Rats, Wistar; Tea

2009
Epigallocatechin-3-gallate attenuates cardiac hypertrophy in hypertensive rats in part by modulation of mitogen-activated protein kinase signals.
    Clinical and experimental pharmacology & physiology, 2009, Volume: 36, Issue:9

    Topics: Animals; Antioxidants; Atrial Natriuretic Factor; Catalase; Catechin; Disease Models, Animal; DNA, Mitochondrial; Electron Transport Chain Complex Proteins; Enzyme Activation; Glutathione Peroxidase; Hemodynamics; Hypertension; Hypertrophy, Left Ventricular; Male; Malondialdehyde; MAP Kinase Signaling System; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Mitochondria, Heart; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 8; Mitogen-Activated Protein Kinases; Myocardium; Myosin Heavy Chains; Natriuretic Peptide, Brain; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Superoxide Dismutase; Transcription Factor AP-1

2009
Effects of Pithecellobium clypearia Benth extract and its main components on inflammation and allergy.
    Fitoterapia, 2009, Volume: 80, Issue:6

    Topics: Animals; Anti-Allergic Agents; Anti-Inflammatory Agents; Benzopyrans; Carrageenan; Catechin; Croton Oil; Disease Models, Animal; Edema; Fabaceae; Histamine Antagonists; Hypersensitivity; Inflammation; Lipopolysaccharides; Liver; Male; Mast Cells; Mice; Molecular Structure; Plant Extracts; Plant Leaves; Plant Stems; Propionibacterium acnes; Rats

2009
Effects of Pinus brutia bark extract and Pycnogenol in a rat model of carrageenan induced inflammation.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2009, Volume: 16, Issue:12

    Topics: Animals; Anti-Inflammatory Agents; Carrageenan; Catechin; Disease Models, Animal; Dose-Response Relationship, Drug; Edema; Flavonoids; Inflammation; Male; Phytotherapy; Pinus; Plant Bark; Plant Extracts; Quercetin; Rats; Rats, Wistar

2009
Effect of lycopene and epigallocatechin-3-gallate against 3-nitropropionic acid induced cognitive dysfunction and glutathione depletion in rat: a novel nitric oxide mechanism.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2009, Volume: 47, Issue:10

    Topics: Animals; Brain; Carotenoids; Catechin; Disease Models, Animal; Glutathione; Huntington Disease; Lycopene; Male; Maze Learning; Memory Disorders; Neuroprotective Agents; Nitric Oxide; Oxidative Stress; Rats

2009
Epigallocatechin gallate ameliorates chronic fatigue syndrome in mice: behavioral and biochemical evidence.
    Behavioural brain research, 2009, Dec-28, Volume: 205, Issue:2

    Topics: Animals; Antioxidants; Brucella abortus; Catalase; Catechin; Disease Models, Animal; Fatigue Syndrome, Chronic; Glutathione; Hyperalgesia; Lipid Peroxidation; Lipopolysaccharides; Locomotion; Mice; Mice, Inbred Strains; Nitrites; Oxidative Stress; Superoxide Dismutase; Swimming; Transforming Growth Factor beta; Tumor Necrosis Factor-alpha

2009
Inhibition of cyclooxygenase-2 expression and prostaglandin E2 production in chondrocytes by avocado soybean unsaponifiables and epigallocatechin gallate.
    Osteoarthritis and cartilage, 2010, Volume: 18, Issue:2

    Topics: Aggrecans; Animals; Antioxidants; Cartilage, Articular; Catechin; Chondrocytes; Collagen Type II; Cyclooxygenase 2; Dinoprostone; Disease Models, Animal; Gene Expression; Glycine max; Horses; Interleukin-1beta; NF-kappa B; Persea; Phenotype; Plant Extracts; Polymerase Chain Reaction; RNA; Tumor Necrosis Factor-alpha

2010
Protective effects of epigallocatechin gallate following 3-nitropropionic acid-induced brain damage: possible nitric oxide mechanisms.
    Psychopharmacology, 2009, Volume: 207, Issue:2

    Topics: Animals; Antioxidants; Behavior, Animal; Catechin; Disease Models, Animal; Dose-Response Relationship, Drug; Male; Mitochondria; Motor Activity; Neurodegenerative Diseases; Neuroprotective Agents; Neurotoxicity Syndromes; Neurotoxins; Nitric Oxide; Nitro Compounds; Oxidative Stress; Propionates; Rats; Rats, Wistar

2009
Supplementary catechins attenuate cooking-oil-fumes-induced oxidative stress in rat lung.
    The Chinese journal of physiology, 2009, Jun-30, Volume: 52, Issue:3

    Topics: Acute Lung Injury; Aldehydes; Animals; Apoptosis; bcl-2-Associated X Protein; Catechin; Cooking; Dietary Supplements; Disease Models, Animal; Female; HSP70 Heat-Shock Proteins; Oils; Oxidative Stress; Pneumonia; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Wistar; Reactive Oxygen Species; Time Factors; Tyrosine

2009
Regulatory effect of epigallocatechin gallate on the expression of C-reactive protein and other inflammatory markers in an experimental model of atherosclerosis.
    Chemico-biological interactions, 2010, Jan-05, Volume: 183, Issue:1

    Topics: Animals; Aorta, Thoracic; Atherosclerosis; Biomarkers; Blood Sedimentation; C-Reactive Protein; Catechin; Diet, Atherogenic; Disease Models, Animal; Inflammation; Injections, Intraperitoneal; Lymphocyte Count; Male; Platelet Count; Rats; Rats, Wistar

2010
Early intervention of tyrosine nitration prevents vaso-obliteration and neovascularization in ischemic retinopathy.
    The Journal of pharmacology and experimental therapeutics, 2010, Volume: 332, Issue:1

    Topics: Acetylcysteine; Animals; Animals, Newborn; Apoptosis; Blotting, Western; Catechin; Cells, Cultured; Disease Models, Animal; Endothelial Cells; Glutathione; Hyperoxia; Hypoxia; Ischemia; Lipid Peroxidation; Metalloporphyrins; Mice; Mice, Inbred C57BL; Peroxynitrous Acid; Protective Agents; Retinal Neovascularization; Retinal Vessels; Tyrosine

2010
The effect of epigallocatechin gallate on lipopolysaccharide-induced acute lung injury in a murine model.
    Inflammation, 2010, Volume: 33, Issue:2

    Topics: Acute Lung Injury; Animals; Bronchoalveolar Lavage Fluid; Catechin; Cell Line; Chemokine CXCL2; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Activation; JNK Mitogen-Activated Protein Kinases; Lipopolysaccharides; Lung; Macrophages; Male; Mice; Mice, Inbred ICR; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Neutrophil Infiltration; Organ Size; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Severity of Illness Index; Tumor Necrosis Factor-alpha

2010
(-)-Epigallocatechin gallate sensitizes breast cancer cells to paclitaxel in a murine model of breast carcinoma.
    Breast cancer research : BCR, 2010, Volume: 12, Issue:1

    Topics: Animals; Apoptosis; Catechin; Cell Line, Tumor; Disease Models, Animal; Drug Synergism; Endoplasmic Reticulum Chaperone BiP; Female; Heat-Shock Proteins; Humans; JNK Mitogen-Activated Protein Kinases; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Paclitaxel

2010
Protective effect of epigallocatechin gallate in murine water-immersion stress model of chronic fatigue syndrome.
    Basic & clinical pharmacology & toxicology, 2010, Volume: 106, Issue:6

    Topics: Administration, Oral; Animals; Antioxidants; Brain; Catechin; Disease Models, Animal; Dose-Response Relationship, Drug; Fatigue Syndrome, Chronic; Mice; Oxidative Stress; Spleen; Swimming; Thymus Gland; Tumor Necrosis Factor-alpha

2010
The antioxidant effect of green tea catechin ameliorates experimental liver injury.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2010, Volume: 17, Issue:3-4

    Topics: Actins; Alanine Transaminase; Aldehydes; Animals; Antioxidants; Aspartate Aminotransferases; Camellia sinensis; Catechin; Cholestasis; Deoxyguanosine; Disease Models, Animal; Hepatic Stellate Cells; Liver; Liver Cirrhosis; Male; Oxidative Stress; Phytotherapy; Plant Extracts; Rats; Rats, Wistar; RNA, Messenger; Tissue Inhibitor of Metalloproteinase-1; Transcription Factor AP-1; Transforming Growth Factor beta1

2010
Specific dietary polyphenols attenuate atherosclerosis in apolipoprotein E-knockout mice by alleviating inflammation and endothelial dysfunction.
    Arteriosclerosis, thrombosis, and vascular biology, 2010, Volume: 30, Issue:4

    Topics: Animals; Anti-Inflammatory Agents; Aorta; Aortic Diseases; Apolipoproteins E; Atherosclerosis; Biflavonoids; Biomarkers; Catechin; Chlorogenic Acid; Cholesterol; Diet; Dioxoles; Disease Models, Animal; Endothelin-1; Endothelium, Vascular; F2-Isoprostanes; Fatty Acids; Flavonoids; Heme Oxygenase-1; Inflammation; Leukotriene B4; Lignans; Male; Membrane Proteins; Mice; Mice, Inbred C57BL; Mice, Knockout; Nitrates; Nitric Oxide; Nitric Oxide Synthase Type III; Nitrites; Oxidative Stress; P-Selectin; Phenols; Polyphenols; Quercetin; Superoxides

2010
Low dosage of rasagiline and epigallocatechin gallate synergistically restored the nigrostriatal axis in MPTP-induced parkinsonism.
    Neuro-degenerative diseases, 2010, Volume: 7, Issue:4

    Topics: Animals; Antioxidants; Catechin; Cell Line; Corpus Striatum; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Combinations; Drug Synergism; Indans; Male; Mice; Mice, Inbred C57BL; Neural Pathways; Neuroprotective Agents; Parkinsonian Disorders; Recovery of Function; Substantia Nigra; Treatment Outcome

2010
Late chronic catechin antioxidant treatment is deleterious to the endothelial function in aging mice with established atherosclerosis.
    American journal of physiology. Heart and circulatory physiology, 2010, Volume: 298, Issue:6

    Topics: Aging; Animals; Antioxidants; Apolipoproteins B; Atherosclerosis; Catechin; Disease Models, Animal; Dose-Response Relationship, Drug; Endothelium, Vascular; Lipids; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Oxidative Stress; Reactive Oxygen Species; Receptors, LDL; Superoxides

2010
The functional effect of epigallocatechin gallate on ischemic stroke in rats.
    Acta neurobiologiae experimentalis, 2010, Volume: 70, Issue:1

    Topics: Animals; Behavior, Animal; Brain Infarction; Catechin; Disease Models, Animal; Hindlimb; Infarction, Middle Cerebral Artery; Male; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Sensory Gating; Statistics, Nonparametric

2010
Epigallocatechin-3-gallate ameliorates hyperglycemia-induced embryonic vasculopathy and malformation by inhibition of Foxo3a activation.
    American journal of obstetrics and gynecology, 2010, Volume: 203, Issue:1

    Topics: Animals; Antioxidants; Blotting, Western; Catechin; Disease Models, Animal; Embryonic Development; Female; Fetus; Forkhead Box Protein O3; Forkhead Transcription Factors; Hyperglycemia; In Vitro Techniques; Oxidative Stress; Phosphorylation; Pregnancy; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Signal Transduction; Yolk Sac

2010
Neuroprotective effects of Epigallocatechin-3-gallate (EGCG) in optic nerve crush model in rats.
    Neuroscience letters, 2010, Jul-19, Volume: 479, Issue:1

    Topics: Animals; Catechin; Cell Count; Cell Survival; Disease Models, Animal; Female; Nerve Crush; Neurofilament Proteins; Neuroprotective Agents; Optic Nerve Injuries; Random Allocation; Rats; Rats, Wistar; Retina; Retinal Ganglion Cells; Time Factors; Treatment Outcome

2010
Antioxidant, antimutagenic, and antidiabetic activities of edible leaves from Cnidoscolus chayamansa Mc. Vaugh.
    Journal of food science, 2010, Volume: 75, Issue:2

    Topics: Animals; Antimutagenic Agents; Antioxidants; Catechin; Chromatography, High Pressure Liquid; Diabetes Mellitus, Experimental; Disease Models, Animal; Euphorbiaceae; Flavonoids; Gallic Acid; Hydroxybenzoates; Hypoglycemic Agents; Mutagenicity Tests; Phenols; Plant Extracts; Plant Leaves; Rats; Rats, Wistar; Rutin

2010
Inhibition of inducible nitric oxide synthase expression and cell death by (-)-epigallocatechin-3-gallate, a green tea catechin, in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson's disease.
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2010, Volume: 17, Issue:9

    Topics: Animals; Catechin; Cell Death; Disease Models, Animal; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Male; Mice; Mice, Inbred C57BL; MPTP Poisoning; Nitric Oxide Synthase Type II; Parkinsonian Disorders; Tea

2010
Effects of (-)-epicatechin on myocardial infarct size and left ventricular remodeling after permanent coronary occlusion.
    Journal of the American College of Cardiology, 2010, Jun-22, Volume: 55, Issue:25

    Topics: Administration, Oral; Analysis of Variance; Animals; Catechin; Coronary Circulation; Coronary Occlusion; Disease Models, Animal; Hemodynamics; Male; Myocardial Infarction; Myocardial Reperfusion Injury; Probability; Radiography; Random Allocation; Rats; Rats, Sprague-Dawley; Reference Values; Survival Rate; Treatment Outcome; Ventricular Remodeling

2010
(-)-Epigallocatechin-3-O-gallate (EGCG) reverses caffeine-induced anxiogenic-like effects.
    Neuroscience letters, 2010, Sep-06, Volume: 481, Issue:2

    Topics: Animals; Anxiety; Caffeine; Catechin; Central Nervous System Stimulants; Disease Models, Animal; Dose-Response Relationship, Drug; Electroencephalography; Male; Maze Learning; Mice; Mice, Inbred ICR; Neuroprotective Agents; Rats; Rats, Wistar; Spectrum Analysis

2010
Anti-inflammatory and antimicrobial effects of nanocatechin in a chronic bacterial prostatitis rat model.
    Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy, 2011, Volume: 17, Issue:2

    Topics: Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents; Catechin; Chronic Disease; Disease Models, Animal; Escherichia coli; Escherichia coli Infections; Humans; Male; Prostate; Prostatitis; Rats; Rats, Wistar

2011
Amelioration of functional, biochemical and molecular deficits by epigallocatechin gallate in experimental model of alcoholic neuropathy.
    European journal of pain (London, England), 2011, Volume: 15, Issue:3

    Topics: Alcoholic Neuropathy; Analysis of Variance; Animals; Behavior, Animal; Catechin; Cytokines; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Hyperalgesia; Male; Oxidative Stress; Physical Stimulation; Rats; Rats, Wistar; Urokinase-Type Plasminogen Activator

2011
[Protective activity of different concentration of tea polyphenols and its major compound EGCG against whole body irradiation-induced injury in mice].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2010, Volume: 35, Issue:10

    Topics: Animals; Camellia sinensis; Catechin; Disease Models, Animal; Female; Flavonoids; Humans; Male; Mice; Phenols; Plant Extracts; Polyphenols; Radiation Injuries; Radiation-Protective Agents; Random Allocation; Superoxide Dismutase; Whole-Body Irradiation

2010
Dietary soy and tea mitigate chronic inflammation and prostate cancer via NFκB pathway in the Noble rat model.
    The Journal of nutritional biochemistry, 2011, Volume: 22, Issue:5

    Topics: Animals; Anti-Inflammatory Agents; Antineoplastic Agents; bcl-2-Associated X Protein; Catechin; Chronic Disease; Diet; Disease Models, Animal; Estradiol; Glycine max; I-kappa B Proteins; Inflammation; Interleukin-1beta; Interleukin-6; Isoflavones; Male; NF-kappa B; NF-KappaB Inhibitor alpha; Prostatic Neoplasms; Rats; Signal Transduction; Soy Foods; Tea; Testosterone; Tumor Necrosis Factor-alpha

2011
EGCG functions through estrogen receptor-mediated activation of ADAM10 in the promotion of non-amyloidogenic processing of APP.
    FEBS letters, 2010, Oct-08, Volume: 584, Issue:19

    Topics: ADAM Proteins; ADAM10 Protein; Alzheimer Disease; Amyloid beta-Protein Precursor; Amyloid Precursor Protein Secretases; Animals; Catechin; Cell Line; Disease Models, Animal; Estrogen Receptor alpha; Female; Furin; Humans; Membrane Proteins; Mice; Models, Biological; Neuroprotective Agents; Phosphatidylinositol 3-Kinases; Protein Processing, Post-Translational; Proto-Oncogene Proteins c-akt; Signal Transduction

2010
Supplementation of green tea catechins in dentifrices suppresses gingival oxidative stress and periodontal inflammation.
    Archives of oral biology, 2011, Volume: 56, Issue:1

    Topics: Alveolar Bone Loss; Animals; Antioxidants; Camellia sinensis; Catechin; Connective Tissue; Dentifrices; Disease Models, Animal; Epithelial Attachment; Gingiva; Gingival Recession; Lipid Peroxidation; Lysine; Male; NF-kappa B; Oxidative Stress; Periodontitis; Random Allocation; Rats; Rats, Wistar; Tumor Necrosis Factor-alpha; Tyrosine

2011
Flavocoxid, a dual inhibitor of cyclooxygenase-2 and 5-lipoxygenase, reduces pancreatic damage in an experimental model of acute pancreatitis.
    British journal of pharmacology, 2010, Volume: 161, Issue:5

    Topics: Acute Disease; Animals; Arachidonate 5-Lipoxygenase; Catechin; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Disease Models, Animal; Drug Combinations; Gene Expression Regulation; Inflammation; Lipoxygenase Inhibitors; Male; Pancreatitis; Polymerase Chain Reaction; Rats; Rats, Sprague-Dawley

2010
Biological actions of green tea catechins on cardiac troponin C.
    British journal of pharmacology, 2010, Volume: 161, Issue:5

    Topics: Actin Cytoskeleton; Animals; Calcium; Cardiomyopathy, Hypertrophic; Catechin; Disease Models, Animal; Humans; Magnetic Resonance Spectroscopy; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Myocardial Contraction; Quartz Crystal Microbalance Techniques; Rabbits; Stereoisomerism; Tea; Troponin C

2010
Cardioprotective effects of epigallocatechin-3-gallate against doxorubicin-induced cardiomyocyte injury.
    European journal of pharmacology, 2011, Feb-10, Volume: 652, Issue:1-3

    Topics: Animals; Antioxidants; Catechin; Disease Models, Animal; Dose-Response Relationship, Drug; Doxorubicin; Male; Myocytes, Cardiac; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species

2011
Antinociceptive effect on mice of the hydroalcoholic fraction and (-) epicatechin obtained from Combretum leprosum Mart & Eich.
    Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, 2010, Volume: 43, Issue:12

    Topics: Acute Disease; Analgesics; Animals; Catechin; Combretum; Disease Models, Animal; Dose-Response Relationship, Drug; Flavonoids; Male; Mice; Pain; Pain Measurement; Plant Extracts

2010
Down-regulation of NF-κB signalling by polyphenolic compounds prevents endotoxin-induced liver injury in a rat model.
    Innate immunity, 2012, Volume: 18, Issue:1

    Topics: Animals; Antioxidants; Catechin; Disease Models, Animal; Endotoxins; Female; Humans; Liver Diseases; NF-kappa B; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type II; Oxidative Stress; Polyphenols; Quercetin; Rats; Rats, Wistar; Sepsis; Signal Transduction; Tumor Necrosis Factor-alpha

2012
Green tea epigallocatechin gallate enhances therapeutic efficacy of temozolomide in orthotopic mouse glioblastoma models.
    Cancer letters, 2011, Mar-28, Volume: 302, Issue:2

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Camellia sinensis; Catechin; Cell Line, Tumor; Dacarbazine; Disease Models, Animal; Drug Synergism; Endoplasmic Reticulum Chaperone BiP; Glioblastoma; Humans; Immunohistochemistry; Mice; Mice, Knockout; Temozolomide

2011
Epigallocatechin-3-gallate reduces airway inflammation in mice through binding to proinflammatory chemokines and inhibiting inflammatory cell recruitment.
    Journal of immunology (Baltimore, Md. : 1950), 2011, Mar-15, Volume: 186, Issue:6

    Topics: Animals; Binding Sites; Catechin; Cell Migration Inhibition; Cells, Cultured; Chemokine CXCL10; Chemokine CXCL11; Chemokine CXCL9; Chemokines; Disease Models, Animal; Inflammation Mediators; Lung; Male; Mice; Mice, Inbred BALB C; Mice, SCID; Mice, Transgenic

2011
Polyphenols from Parabarium huaitingii and their positive inotropic and anti-myocardial infarction effects in rats.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2011, May-15, Volume: 18, Issue:7

    Topics: Animals; Apocynaceae; Calcium; Cardiotonic Agents; Catechin; Disease Models, Animal; Dose-Response Relationship, Drug; Heart; Medicine, Chinese Traditional; Myocardial Contraction; Myocardial Infarction; Plant Extracts; Plant Stems; Plants, Medicinal; Proanthocyanidins; Prohibitins; Random Allocation; Rats; Rats, Wistar; Stimulation, Chemical

2011
Epigallocatechin gallate accelerates healing of indomethacin-induced stomach ulcers in mice.
    Pharmacological reports : PR, 2011, Volume: 63, Issue:2

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Antioxidants; Catechin; Disease Models, Animal; Gastric Mucosa; Indomethacin; Lipid Peroxidation; Male; Mice; Omeprazole; Oxidative Stress; Stomach Ulcer; Tea

2011
Chemopreventive effect of epigallocatechin-3-gallate (EGCG) and folic acid on the N-methyl-N'-nitro-N-nitrosoguanidine (MNNG)-induced gastrointestinal cancer in rat model.
    Journal of digestive diseases, 2011, Volume: 12, Issue:3

    Topics: Adenocarcinoma; Administration, Oral; Animals; Anticarcinogenic Agents; Apoptosis; Catechin; Cell Proliferation; Disease Models, Animal; Drug Therapy, Combination; Folic Acid; Gastrointestinal Neoplasms; Hematinics; Male; Methylnitronitrosoguanidine; Rats; Rats, Wistar; Sarcoma; Treatment Outcome

2011
Catechin suppresses an array of signalling molecules and modulates alcohol-induced endotoxin mediated liver injury in a rat model.
    PloS one, 2011, Volume: 6, Issue:6

    Topics: Alcohols; Animals; Antioxidants; Catechin; Cell Nucleus; Chemical and Drug Induced Liver Injury; Disease Models, Animal; Endotoxins; Female; Liver; Malondialdehyde; NF-kappa B; Nitrites; Rats; Rats, Wistar; Signal Transduction; Tumor Necrosis Factor-alpha

2011
A comparative study of the inhibiting effects of mitomycin C and polyphenolic catechins on tumor cell implantation/growth in a rat bladder tumor model.
    The Journal of urology, 2011, Volume: 186, Issue:2

    Topics: Animals; Antibiotics, Antineoplastic; Anticarcinogenic Agents; Catechin; Cell Line, Tumor; Cell Proliferation; Disease Models, Animal; Drug Screening Assays, Antitumor; Female; Mitomycin; Rats; Rats, Inbred F344; Urinary Bladder Neoplasms

2011
Phytotherapy in a rat model of hyperoxaluria: the antioxidant effects of quercetin involve serum paraoxonase 1 activation.
    Experimental biology and medicine (Maywood, N.J.), 2011, Volume: 236, Issue:10

    Topics: Animals; Antioxidants; Apolipoprotein A-I; Aryldialkylphosphatase; Blotting, Western; Catechin; Cholesterol, HDL; Clusterin; Disease Models, Animal; Enzyme Activation; Ethylene Glycol; Hyperoxaluria; Male; Oxidative Stress; Phytotherapy; Plant Preparations; Quercetin; Rats; Rats, Wistar; Renal Insufficiency

2011
Catechins attenuate eccentric exercise-induced inflammation and loss of force production in muscle in senescence-accelerated mice.
    Journal of applied physiology (Bethesda, Md. : 1985), 2011, Volume: 111, Issue:6

    Topics: Aging, Premature; Alanine Transaminase; Animals; Aspartate Aminotransferases; Calcium-Transporting ATPases; Catechin; Chemokine CCL2; Disease Models, Animal; Glutathione; Glutathione Disulfide; Inflammation; Interleukin-6; Male; Malondialdehyde; Mice; Muscle Contraction; Muscle, Skeletal; Oxidative Stress; Physical Endurance; Running; Sodium-Potassium-Exchanging ATPase; Tumor Necrosis Factor-alpha

2011
Effects of green tea polyphenol (-)-epigallocatechin-3-gallate on newly developed high-fat/Western-style diet-induced obesity and metabolic syndrome in mice.
    Journal of agricultural and food chemistry, 2011, Nov-09, Volume: 59, Issue:21

    Topics: Animals; Blood Glucose; Body Weight; Catechin; Diet, High-Fat; Disease Models, Animal; Humans; Male; Metabolic Syndrome; Mice; Mice, Inbred C57BL; Obesity; Plant Extracts; Polyphenols

2011
Chronic administration of green tea extract to TRAMP mice induces the collapse of Golgi apparatus in prostate secretory cells and results in alterations of protein post-translational processing.
    International journal of oncology, 2011, Volume: 39, Issue:6

    Topics: Adenocarcinoma; Animals; Catechin; Clusterin; Disease Models, Animal; Endoplasmic Reticulum; Golgi Apparatus; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Prostatic Neoplasms; Protein Processing, Post-Translational; Tea

2011
Effects of topical application of EGCG on testosterone-induced hair loss in a mouse model.
    Experimental dermatology, 2011, Volume: 20, Issue:12

    Topics: 17-Hydroxysteroid Dehydrogenases; 3-Hydroxysteroid Dehydrogenases; Alopecia; Animals; Antioxidants; Apoptosis; Catechin; Cyproterone Acetate; Dihydrotestosterone; Disease Models, Animal; Down-Regulation; Epithelial Cells; Female; Hair; Hair Follicle; Mice; Mice, Inbred CBA; Receptors, Androgen; Sebaceous Glands; Testosterone

2011
Therapeutic efficacy of topical epigallocatechin gallate in murine dry eye.
    Cornea, 2011, Volume: 30, Issue:12

    Topics: Animals; Antioxidants; Catechin; Chemokines; Cornea; Disease Models, Animal; Dry Eye Syndromes; Female; Fluorescein; Immunohistochemistry; Interleukin-1beta; Mice; Mice, Inbred C57BL; Tumor Necrosis Factor-alpha; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor D

2011
Neuroprotection of green tea catechins on surgical menopause-induced overactive bladder in a rat model.
    Menopause (New York, N.Y.), 2012, Volume: 19, Issue:3

    Topics: Animals; Catechin; Disease Models, Animal; Female; Menopause; Neuroprotective Agents; Ovariectomy; Rats; Rats, Sprague-Dawley; Receptor, Muscarinic M2; Receptor, Muscarinic M3; Tea; Urinary Bladder, Overactive

2012
Antiosteoporotic activity of Davallia formosana.
    Journal of ethnopharmacology, 2012, Jan-31, Volume: 139, Issue:2

    Topics: Alendronate; Alkaline Phosphatase; Amino Acids; Animals; Biomechanical Phenomena; Bone Density; Bone Density Conservation Agents; Bone Remodeling; Calcium; Catechin; Cell Differentiation; Cell Line; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Femur; Mice; Osteoclasts; Osteoporosis; Ovariectomy; Plant Extracts; Plants, Medicinal; Polypodiaceae; RANK Ligand; Rats; Rats, Wistar; Rhizome; Solvents; Time Factors; X-Ray Microtomography

2012
Epicatechin-rich cocoa polyphenol inhibits Kras-activated pancreatic ductal carcinoma cell growth in vitro and in a mouse model.
    International journal of cancer, 2012, Oct-01, Volume: 131, Issue:7

    Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Cacao; Carcinoma, Pancreatic Ductal; Catechin; Cell Cycle Checkpoints; Cell Proliferation; Cell Transformation, Neoplastic; Disease Models, Animal; Genes, ras; Humans; Mice; Mice, Nude; NF-kappa B; Pancreatic Neoplasms; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Polyphenols; Proto-Oncogene Proteins c-akt; Tandem Mass Spectrometry; Transcription, Genetic

2012
Flavangenol (pine bark extract) and its major component procyanidin B1 enhance fatty acid oxidation in fat-loaded models.
    European journal of pharmacology, 2012, Feb-29, Volume: 677, Issue:1-3

    Topics: Animals; Biflavonoids; Catechin; Diabetes Mellitus; Disease Models, Animal; Fatty Acids; Fatty Liver; Gene Expression Regulation, Enzymologic; Hep G2 Cells; Humans; Lipid Metabolism; Liver; Liver Function Tests; Male; Mice; Non-alcoholic Fatty Liver Disease; Obesity; Oxidation-Reduction; Pinus; Plant Bark; Plant Extracts; Proanthocyanidins; RNA, Messenger; Tomography, X-Ray Computed

2012
Role of neuronal nitric oxide synthase in the antiallodynic effects of intrathecal EGCG in a neuropathic pain rat model.
    Neuroscience letters, 2012, Feb-21, Volume: 510, Issue:1

    Topics: Animals; Arginine; Catechin; Disease Models, Animal; Extremities; Hyperalgesia; Injections, Spinal; Ligation; Male; Neuralgia; Nitric Oxide; Nitric Oxide Synthase Type I; Rats; Rats, Sprague-Dawley; Spinal Cord; Spinal Nerves

2012
Epigallocatechin-3-gallate as a potential therapeutic drug for TTR-related amyloidosis: "in vivo" evidence from FAP mice models.
    PloS one, 2012, Volume: 7, Issue:1

    Topics: Amyloid; Amyloid Neuropathies, Familial; Animals; Biomarkers; Catechin; Colon; Disease Models, Animal; Endoplasmic Reticulum Stress; Gastric Mucosa; Humans; Mice; Mice, Transgenic; Peripheral Nervous System; Prealbumin; Stomach

2012
Catechin prevents severe dyslipidemia-associated changes in wall biomechanics of cerebral arteries in LDLr-/-:hApoB+/+ mice and improves cerebral blood flow.
    American journal of physiology. Heart and circulatory physiology, 2012, Mar-15, Volume: 302, Issue:6

    Topics: Animals; Antioxidants; Apolipoproteins B; Biomechanical Phenomena; Catechin; Cerebral Arteries; Cerebrovascular Circulation; Compliance; Disease Models, Animal; Dyslipidemias; Endothelium, Vascular; Enzyme Precursors; Genotype; Humans; Intracranial Arteriosclerosis; Male; Matrix Metalloproteinase 9; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Phenotype; Receptors, LDL; Severity of Illness Index; Stress, Mechanical; Tomography, Optical Coherence; Vasodilation

2012
Quantitative evaluation of the beneficial effects in the mdx mouse of epigallocatechin gallate, an antioxidant polyphenol from green tea.
    Histochemistry and cell biology, 2012, Volume: 137, Issue:6

    Topics: Animals; Antioxidants; Body Weight; Catechin; Disease Models, Animal; Eating; Female; Male; Mice; Mice, Inbred C57BL; Mice, Inbred mdx; Muscular Dystrophy, Duchenne; Oxidative Stress; Polyphenols; Tea

2012
Flavocoxid, a dual inhibitor of COX-2 and 5-LOX of natural origin, attenuates the inflammatory response and protects mice from sepsis.
    Critical care (London, England), 2012, Feb-22, Volume: 16, Issue:1

    Topics: Animals; Arrestins; beta-Arrestin 2; beta-Arrestins; Catechin; Cyclooxygenase 2 Inhibitors; Cytokines; Dinoprostone; Disease Models, Animal; Drug Combinations; Extracellular Signal-Regulated MAP Kinases; Intracellular Signaling Peptides and Proteins; Leukotriene B4; Lipoxins; Lipoxygenase Inhibitors; Liver; Lung; Mice, Inbred C57BL; NF-kappa B; Peroxidase; Sepsis

2012
Procyanidin B3 prevents articular cartilage degeneration and heterotopic cartilage formation in a mouse surgical osteoarthritis model.
    PloS one, 2012, Volume: 7, Issue:5

    Topics: Animals; Apoptosis; Biflavonoids; Cartilage, Articular; Catechin; Cell Differentiation; Chondrocytes; Disease Models, Animal; Knee Joint; Male; Mice; Nitric Oxide Synthase Type I; Ossification, Heterotopic; Osteoarthritis, Knee; Proanthocyanidins

2012
Theaflavin ameliorates behavioral deficits, biochemical indices and monoamine transporters expression against subacute 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced mouse model of Parkinson's disease.
    Neuroscience, 2012, Aug-30, Volume: 218

    Topics: Animals; Behavior, Animal; Biflavonoids; Blotting, Western; Catechin; Disease Models, Animal; Immunohistochemistry; Male; Mice; Mice, Inbred C57BL; Neuroprotective Agents; Oxidative Stress; Parkinsonian Disorders; Vesicular Monoamine Transport Proteins

2012
Green tea catechins decrease oxidative stress in surgical menopause-induced overactive bladder in a rat model.
    BJU international, 2012, Volume: 110, Issue:6 Pt B

    Topics: Animals; Antioxidants; Catechin; Disease Models, Animal; Female; Menopause; Ovariectomy; Oxidative Stress; Plant Extracts; Rats; Rats, Sprague-Dawley; Tea; Urinary Bladder, Overactive

2012
Renoprotective effects of (+)-catechin in streptozotocin-induced diabetic rat model.
    Nutrition research (New York, N.Y.), 2012, Volume: 32, Issue:5

    Topics: Alanine Transaminase; Albuminuria; Angiotensin-Converting Enzyme Inhibitors; Animals; Anti-Inflammatory Agents; Antioxidants; Camellia sinensis; Catechin; Creatinine; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Disease Models, Animal; Enalapril; Endothelin-1; Fibronectins; Lipid Peroxidation; Male; Oxidative Stress; Phytotherapy; Plant Extracts; Rats; Rats, Sprague-Dawley; Sulfhydryl Compounds

2012
Therapeutic attenuation of neuroinflammation and apoptosis by black tea theaflavin in chronic MPTP/probenecid model of Parkinson's disease.
    Neurotoxicity research, 2013, Volume: 23, Issue:2

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Antioxidants; Apoptosis; bcl-2-Associated X Protein; Biflavonoids; Catechin; Cyclooxygenase 2; Cytokines; Disease Models, Animal; Dyskinesias; Encephalitis; Glial Fibrillary Acidic Protein; Male; Mice; Mice, Inbred C57BL; MPTP Poisoning; Probenecid; Proto-Oncogene Proteins c-bcl-2; Reaction Time

2013
Deleterious effects of high concentrations of (-)-epigallocatechin-3-gallate and atorvastatin in mice with colon inflammation.
    Nutrition and cancer, 2012, Volume: 64, Issue:6

    Topics: Animals; Atorvastatin; Azoxymethane; Catechin; Colitis; Colon; Colonic Neoplasms; Dextran Sulfate; Dinoprostone; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Gastrointestinal Hemorrhage; Heptanoic Acids; Leukotriene B4; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Pyrroles; Rectum; Weight Loss

2012
Beneficial effects of (-)-epigallocatechin gallate on ischemia-reperfusion testicular injury in rats.
    Journal of pediatric surgery, 2012, Volume: 47, Issue:7

    Topics: Animals; Antioxidants; Biomarkers; Catechin; Disease Models, Animal; Male; Postoperative Complications; Random Allocation; Rats; Rats, Wistar; Reperfusion Injury; Spermatic Cord Torsion

2012
A modulating effect of epigallocatechin gallate (EGCG), a tea catechin, on the bladder of rats exposed to water avoidance stress.
    Neurourology and urodynamics, 2013, Volume: 32, Issue:3

    Topics: Animals; Catechin; Cell Degranulation; Cystitis, Interstitial; Defecation; Disease Models, Animal; Female; Immersion; Injections, Intraperitoneal; Mast Cells; Rats; Rats, Sprague-Dawley; Stress, Psychological; Time Factors; Urinary Bladder; Urination; Water

2013
Epigallocatechin-3-gallate modulates antioxidant and DNA repair-related proteins in exocrine glands of a primary Sjogren's syndrome mouse model prior to disease onset.
    Autoimmunity, 2012, Volume: 45, Issue:7

    Topics: Animals; Antibodies, Antinuclear; Antioxidants; Catechin; Disease Models, Animal; DNA Repair; Exocrine Glands; Female; Lymphocytes; Mice; Mice, Inbred NOD; Peroxiredoxin VI; Proliferating Cell Nuclear Antigen; Sjogren's Syndrome; Time Factors

2012
Diverse mechanisms of antidiabetic effects of the different procyanidin oligomer types of two different cinnamon species on db/db mice.
    Journal of agricultural and food chemistry, 2012, Sep-12, Volume: 60, Issue:36

    Topics: Animals; Biflavonoids; Blood Glucose; Catechin; Cinnamomum zeylanicum; Diabetes Mellitus, Type 2; Disease Models, Animal; Female; Humans; Hypoglycemic Agents; Male; Mice; Phytotherapy; Plant Extracts; Proanthocyanidins

2012
Epicatechin limits renal injury by mitochondrial protection in cisplatin nephropathy.
    American journal of physiology. Renal physiology, 2012, Nov-01, Volume: 303, Issue:9

    Topics: Animals; Antioxidants; Catechin; Cells, Cultured; Cisplatin; Cytochromes c; Disease Models, Animal; HeLa Cells; Humans; In Vitro Techniques; Kidney Diseases; Kidney Tubules, Proximal; Male; Mice; Mice, Inbred C57BL; Mitochondria; Mitochondrial Diseases; Oxidative Stress; Reactive Oxygen Species; Succinate Dehydrogenase

2012
Epigallocatechin-3-gallate prevents systemic inflammation-induced memory deficiency and amyloidogenesis via its anti-neuroinflammatory properties.
    The Journal of nutritional biochemistry, 2013, Volume: 24, Issue:1

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Astrocytes; Behavior, Animal; Catechin; Cells, Cultured; Cyclooxygenase 2; Cytokines; Disease Models, Animal; Inflammation; Lipopolysaccharides; Male; Memory Disorders; Mice; Mice, Inbred ICR; Neurons; Nitric Oxide Synthase Type II; Peptide Fragments; Rats

2013
Combination therapy with taurine, epigallocatechin gallate and genistein for protection against hepatic fibrosis induced by alcohol in rats.
    Biological & pharmaceutical bulletin, 2012, Volume: 35, Issue:10

    Topics: Actins; Alanine Transaminase; Alkaline Phosphatase; Animals; Antioxidants; Aspartate Aminotransferases; Catechin; Cytokines; Disease Models, Animal; Drug Therapy, Combination; Ethanol; gamma-Glutamyltransferase; Genistein; Liver Cirrhosis; Peroxidase; Proto-Oncogene Proteins c-bcl-2; Rats; RNA, Messenger; Smad3 Protein; Taurine

2012
Natural therapies assessment for the treatment of endometriosis.
    Human reproduction (Oxford, England), 2013, Volume: 28, Issue:1

    Topics: Angiogenesis Inhibitors; Animals; Antioxidants; Apoptosis; Catechin; Cell Proliferation; Cells, Cultured; Disease Models, Animal; Dose-Response Relationship, Drug; Endometriosis; Endometrium; Female; Humans; Injections, Intraperitoneal; Intestinal Diseases; Mice; Mice, Inbred BALB C; Neovascularization, Pathologic; Random Allocation; Resveratrol; Stilbenes

2013
Green tea extract reverses endothelial dysfunction and reduces atherosclerosis progression in homozygous knockout low-density lipoprotein receptor mice.
    Nutrition research (New York, N.Y.), 2012, Volume: 32, Issue:9

    Topics: Alanine Transaminase; Animals; Antioxidants; Aorta; Atherosclerosis; Biomarkers; Catechin; Chemokine CCL2; Disease Models, Animal; Endothelium, Vascular; Female; Inflammation; Lipoproteins, LDL; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Plant Extracts; Receptors, LDL; Tea; Triglycerides; Tumor Necrosis Factor-alpha

2012
EGCG inhibits CTGF expression via blocking NF-κB activation in cardiac fibroblast.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2013, Jan-15, Volume: 20, Issue:2

    Topics: Animals; Catechin; Cell Proliferation; Cells, Cultured; Collagen; Connective Tissue Growth Factor; Disease Models, Animal; Fibroblasts; Fibronectins; Fibrosis; Gene Expression Regulation, Neoplastic; Humans; Male; Myocardium; NF-kappa B; Plant Extracts; Rats; Rats, Sprague-Dawley; Tea

2013
Neuroprotective effect of (-)-epigallocatechin-3-gallate in rats when administered pre- or post-traumatic brain injury.
    Journal of neural transmission (Vienna, Austria : 1996), 2013, Volume: 120, Issue:5

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Aldehydes; Animals; Brain Edema; Brain Injuries; Catechin; Deoxyguanosine; Disease Models, Animal; DNA, Single-Stranded; Drug Administration Schedule; Glial Fibrillary Acidic Protein; Lipid Peroxidation; Male; Maze Learning; Neurons; Neuroprotective Agents; Phosphopyruvate Hydratase; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Wistar; Time Factors

2013
Beneficial effects of natural phenolics on levodopa methylation and oxidative neurodegeneration.
    Brain research, 2013, Feb-25, Volume: 1497

    Topics: Adrenergic Uptake Inhibitors; Analysis of Variance; Animals; Antiparkinson Agents; Carbidopa; Catechin; Catechol O-Methyltransferase; Chromatography, High Pressure Liquid; Dihydroxyphenylalanine; Disease Models, Animal; Excitatory Amino Acid Agonists; Fluoresceins; Glial Fibrillary Acidic Protein; Hippocampus; Hydroxybenzoates; In Vitro Techniques; Kainic Acid; Levodopa; Male; Methylation; Mice; Nerve Degeneration; Neurons; Rats; Rats, Sprague-Dawley; Reserpine; Time Factors; Tyrosine

2013
(-) Epicatechin attenuates mitochondrial damage by enhancing mitochondrial multi-marker enzymes, adenosine triphosphate and lowering calcium in isoproterenol induced myocardial infarcted rats.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2013, Volume: 53

    Topics: Adenosine Triphosphate; Animals; Antioxidants; Biomarkers; Calcium; Catechin; Citric Acid Cycle; Creatine Kinase; Disease Models, Animal; Electron Transport Complex IV; Glutathione; Glutathione Peroxidase; Glutathione Reductase; Hydroxyl Radical; Isocitrates; Isoproterenol; Ketoglutaric Acids; L-Lactate Dehydrogenase; Lipid Peroxidation; Malates; Male; Microscopy, Electron, Transmission; Mitochondria, Heart; Myocardial Infarction; NADH Dehydrogenase; Rats; Rats, Wistar; Succinic Acid; Superoxide Dismutase; Troponin I

2013
Polyphenon [corrected] E enhances the antitumor immune response in neuroblastoma by inactivating myeloid suppressor cells.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2013, Mar-01, Volume: 19, Issue:5

    Topics: Animals; Catechin; Cells, Cultured; Child; Disease Models, Animal; Granulocyte Colony-Stimulating Factor; Humans; Lymphocytes, Tumor-Infiltrating; Mice; Mice, Inbred A; Mice, Inbred C57BL; Mice, Inbred NOD; Mice, SCID; Mice, Transgenic; Myeloid Cells; Neuroblastoma; Receptors, Laminin; Survival Rate; T-Lymphocytes; Tea

2013
Therapeutic potential of EGCG on acute renal damage in a rat model of obstructive nephropathy.
    Molecular medicine reports, 2013, Volume: 7, Issue:4

    Topics: Acute Kidney Injury; Animals; Antioxidants; Catechin; Disease Models, Animal; Glutathione; Glutathione Disulfide; Humans; Infusions, Parenteral; Kidney; Male; NF-E2-Related Factor 2; Oxidative Stress; Rats; Reactive Oxygen Species; Signal Transduction

2013
Green tea and prostate cancer.
    The Urologic clinics of North America, 2002, Volume: 29, Issue:1

    Topics: Animals; Apoptosis; Catechin; Chemoprevention; Disease Models, Animal; Forecasting; Humans; Male; Mice; Phytotherapy; Prostatic Neoplasms; Receptors, Androgen; Tea

2002
Cocoa extract protects against early alcohol-induced liver injury in the rat.
    Archives of biochemistry and biophysics, 2002, Oct-01, Volume: 406, Issue:1

    Topics: Alanine Transaminase; Aldehydes; Animals; Cacao; Catechin; Celiac Disease; Disease Models, Animal; Enteral Nutrition; Ethanol; Inflammation; Liver Diseases, Alcoholic; Necrosis; Phytotherapy; Plant Extracts; Proteins; Rats; Weight Gain

2002
Lack of inhibitory effects of green tea catechins in 1,2-dimetylhydrazine-induced rat intestinal carcinogenesis model: comparison of the different formulations, administration routes and doses.
    Cancer letters, 2002, Dec-15, Volume: 188, Issue:1-2

    Topics: 1,2-Dimethylhydrazine; Adenoma; Animals; Anticarcinogenic Agents; Body Weight; Carcinogenicity Tests; Carcinogens; Catechin; Disease Models, Animal; Drug Administration Routes; Intestinal Neoplasms; Intestine, Large; Intestine, Small; Male; Rats; Rats, Inbred F344; Tea

2002
Inhibitory effects of epigallocatechin-3-gallate on N-nitrosomethylbenzylamine-induced esophageal tumorigenesis in F344 rats.
    International journal of oncology, 2002, Volume: 21, Issue:6

    Topics: Animals; Anticarcinogenic Agents; Catechin; Cyclin D1; Cyclooxygenase 1; Cyclooxygenase 2; Dimethylnitrosamine; Dinoprostone; Disease Models, Animal; DNA Primers; Enzyme-Linked Immunosorbent Assay; Esophageal Neoplasms; Esophagus; Isoenzymes; Male; Membrane Proteins; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Inbred F344; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Urokinase-Type Plasminogen Activator

2002
Preventive effects of urinary bladder tumors induced by N-butyl-N-(4-hydroxybutyl)-nitrosamine in rat by green tea leaves.
    International journal of urology : official journal of the Japanese Urological Association, 2003, Volume: 10, Issue:3

    Topics: Animals; Anticarcinogenic Agents; Butylhydroxybutylnitrosamine; Camellia sinensis; Catechin; Disease Models, Animal; Dose-Response Relationship, Drug; Male; Phytotherapy; Plant Leaves; Plant Preparations; Rats; Rats, Wistar; Tea; Treatment Outcome; Urinary Bladder Neoplasms

2003
Effects of delayed administration of (-)-epigallocatechin gallate, a green tea polyphenol on the changes in polyamine levels and neuronal damage after transient forebrain ischemia in gerbils.
    Brain research bulletin, 2003, Aug-30, Volume: 61, Issue:4

    Topics: Animals; Antioxidants; Brain Chemistry; Catechin; Cell Survival; Chromatography, High Pressure Liquid; Disease Models, Animal; Flavonoids; Gerbillinae; Hippocampus; Ischemic Attack, Transient; Male; Phenols; Polyamines; Polymers; Prosencephalon; Time Factors

2003
Epigallocatechin gallate can significantly decrease free oxygen radicals in the reperfusion injury in vivo.
    Transplantation proceedings, 2003, Volume: 35, Issue:8

    Topics: Animals; Antioxidants; Catechin; Disease Models, Animal; Femoral Artery; Femoral Vein; Kinetics; Male; Muscle, Skeletal; Rats; Rats, Wistar; Reperfusion Injury; Superoxides

2003
(-)-Epicatechin 3-O-gallate ameliorates the damages related to peroxynitrite production by mechanisms distinct from those of other free radical inhibitors.
    The Journal of pharmacy and pharmacology, 2004, Volume: 56, Issue:2

    Topics: Animals; Azoles; Blood Urea Nitrogen; Catechin; Copper; Creatinine; Disease Models, Animal; Dose-Response Relationship, Drug; Free Radical Scavengers; Isoindoles; Japan; Kidney; Lipopolysaccharides; Lysine; Male; Nitric Oxide; Organoselenium Compounds; Peroxidase; Phytotherapy; Plant Extracts; Plant Roots; Proteinuria; Rats; Rats, Wistar; Reperfusion Injury; Rheum; Superoxide Dismutase; Tyrosine; Uric Acid; Zinc

2004
Administration of procyanidins from grape seeds reduces serum uric acid levels and decreases hepatic xanthine dehydrogenase/oxidase activities in oxonate-treated mice.
    Basic & clinical pharmacology & toxicology, 2004, Volume: 94, Issue:5

    Topics: Allopurinol; Animals; Antioxidants; Biflavonoids; Catechin; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Gout Suppressants; Hyperuricemia; Liver; Male; Mice; Mice, Inbred ICR; Oxonic Acid; Proanthocyanidins; Seeds; Time Factors; Urate Oxidase; Uric Acid; Vitis; Xanthine Dehydrogenase; Xanthine Oxidase

2004
Effects of epicatechin gallate on wound healing and scar formation in a full thickness incisional wound healing model in rats.
    The American journal of pathology, 2004, Volume: 165, Issue:1

    Topics: Animals; Arginase; Blotting, Western; Catechin; Cicatrix; Cyclooxygenase 2; Disease Models, Animal; Injections, Intradermal; Isoenzymes; Male; Neovascularization, Physiologic; Nitric Oxide Synthase; Nitrites; Prostaglandin-Endoperoxide Synthases; Protease Inhibitors; Proteins; Rats; Rats, Sprague-Dawley; Time Factors; Vascular Endothelial Growth Factor A; Wound Healing

2004
Grape seed-derived procyanidins have an antihyperglycemic effect in streptozotocin-induced diabetic rats and insulinomimetic activity in insulin-sensitive cell lines.
    Endocrinology, 2004, Volume: 145, Issue:11

    Topics: 3T3-L1 Cells; Adipocytes; Animals; Biflavonoids; Catechin; Diabetes Mellitus, Experimental; Disease Models, Animal; Glucose; Hyperglycemia; Hypoglycemic Agents; Insulin; Male; Mice; Muscle Fibers, Skeletal; Proanthocyanidins; Rats; Rats, Wistar; Seeds; Vitis

2004
The chemopreventive action of catechins in the TRAMP mouse model of prostate carcinogenesis is accompanied by clusterin over-expression.
    Carcinogenesis, 2004, Volume: 25, Issue:11

    Topics: Animals; Animals, Genetically Modified; Anticarcinogenic Agents; Catechin; Clusterin; Disease Models, Animal; Gene Expression Regulation; Humans; Male; Mice; Mice, Inbred C57BL; Prostatic Neoplasms; Tea

2004
Prostate carcinoma and green tea: (-)epigallocatechin-3-gallate inhibits inflammation-triggered MMP-2 activation and invasion in murine TRAMP model.
    International journal of cancer, 2004, Dec-10, Volume: 112, Issue:5

    Topics: Adenocarcinoma; Animals; Anticarcinogenic Agents; Catechin; Disease Models, Animal; Dose-Response Relationship, Drug; Humans; Inflammation; Male; Matrix Metalloproteinase 2; Mice; Neoplasm Invasiveness; Prostatic Neoplasms; Tea

2004
Iron and alpha-synuclein in the substantia nigra of MPTP-treated mice: effect of neuroprotective drugs R-apomorphine and green tea polyphenol (-)-epigallocatechin-3-gallate.
    Journal of molecular neuroscience : MN, 2004, Volume: 24, Issue:3

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; alpha-Synuclein; Animals; Apomorphine; Catechin; Disease Models, Animal; Free Radicals; Iron; Iron Chelating Agents; Lewy Bodies; Male; Mice; Mice, Inbred C57BL; Nerve Tissue Proteins; Neuroprotective Agents; Oxidative Stress; Parkinsonian Disorders; Substantia Nigra; Synucleins; Ubiquitin

2004
Short-term administration of (-)-epigallocatechin gallate reduces hepatic steatosis and protects against warm hepatic ischemia/reperfusion injury in steatotic mice.
    Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society, 2005, Volume: 11, Issue:3

    Topics: Animals; Antioxidants; Body Weight; Catechin; Disease Models, Animal; Energy Intake; Energy Metabolism; Fatty Liver; Hepatocytes; Liver; Liver Circulation; Male; Mice; Mice, Obese; Necrosis; Reperfusion Injury

2005
Dietary wine phenolics catechin, quercetin, and resveratrol efficiently protect hypercholesterolemic hamsters against aortic fatty streak accumulation.
    Journal of agricultural and food chemistry, 2005, Mar-23, Volume: 53, Issue:6

    Topics: Animals; Aortic Diseases; Arteriosclerosis; Catechin; Cricetinae; Disease Models, Animal; Hypercholesterolemia; Male; Mesocricetus; Quercetin; Resveratrol; Stilbenes; Wine

2005
Green tea extract and catechin ameliorate chronic fatigue-induced oxidative stress in mice.
    Journal of medicinal food, 2005,Spring, Volume: 8, Issue:1

    Topics: Animals; Brain; Catechin; Disease Models, Animal; Dose-Response Relationship, Drug; Fatigue Syndrome, Chronic; Flavonoids; Glutathione; Injections, Intraperitoneal; Lipid Peroxidation; Male; Mice; Oxidative Stress; Phenols; Phytotherapy; Plant Extracts; Polyphenols; Tea

2005
Animal models and analytical approaches for understanding the relationships between wine and cancer.
    Drugs under experimental and clinical research, 2005, Volume: 31, Issue:1

    Topics: Animals; Anticarcinogenic Agents; Carcinogens; Catechin; Disease Models, Animal; DNA Adducts; Dose-Response Relationship, Drug; Human T-lymphotropic virus 1; Humans; Imidazoles; Liver Function Tests; Male; Mice; Mice, Transgenic; Neurofibromatoses; Quercetin; Rats; Rats, Inbred F344; Vitis; Wine

2005
Synergistic effect between catechin and ciprofloxacin on chronic bacterial prostatitis rat model.
    International journal of urology : official journal of the Japanese Urological Association, 2005, Volume: 12, Issue:4

    Topics: Animals; Anti-Infective Agents; Catechin; Chronic Disease; Ciprofloxacin; Colony Count, Microbial; Disease Models, Animal; Escherichia coli; Escherichia coli Infections; Follow-Up Studies; Male; Prostate; Prostatitis; Random Allocation; Rats; Rats, Wistar; Treatment Outcome; Urine

2005
Black tea extract can modulate protein expression of H-ras, c-Myc, p53, and Bcl-2 genes during pulmonary hyperplasia, dysplasia, and carcinoma in situ.
    Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer, 2005, Volume: 24, Issue:3

    Topics: Animals; Animals, Newborn; Anticarcinogenic Agents; Apoptosis; Benzo(a)pyrene; Biflavonoids; Carcinoma in Situ; Catechin; Cell Proliferation; Disease Models, Animal; Female; Gene Expression Regulation, Neoplastic; Hyperplasia; Lung; Lung Neoplasms; Male; Mice; Plant Extracts; Proto-Oncogene Proteins; Proto-Oncogenes; Tea

2005
Molecular classification of green tea catechin-sensitive and green tea catechin-resistant prostate cancer in the TRAMP mice model by quantitative real-time PCR gene profiling.
    Carcinogenesis, 2006, Volume: 27, Issue:5

    Topics: Animals; Anticarcinogenic Agents; Catechin; Disease Models, Animal; DNA Primers; Gene Expression Profiling; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Prognosis; Prostatic Neoplasms; Reverse Transcriptase Polymerase Chain Reaction; Tea

2006
The effect of epigallocatechin gallate on suppressing disease progression of ALS model mice.
    Neuroscience letters, 2006, Mar-06, Volume: 395, Issue:2

    Topics: Amyotrophic Lateral Sclerosis; Animals; Blotting, Western; Caspase 3; Caspases; Catechin; Disease Models, Animal; Disease Progression; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Humans; Mice; Mice, Transgenic; Motor Activity; Mutation; Neuroprotective Agents; Phosphatidylinositol 3-Kinases; Spinal Cord; Superoxide Dismutase; Superoxide Dismutase-1

2006
Green tea extract and its major polyphenol (-)-epigallocatechin gallate improve muscle function in a mouse model for Duchenne muscular dystrophy.
    American journal of physiology. Cell physiology, 2006, Volume: 290, Issue:2

    Topics: Animals; Antioxidants; Camellia sinensis; Catechin; Diet; Disease Models, Animal; Free Radical Scavengers; Humans; Mice; Mice, Inbred C57BL; Mice, Inbred mdx; Muscle Contraction; Muscle, Skeletal; Muscular Dystrophy, Duchenne; Pentoxifylline; Phytotherapy; Plant Extracts; Plant Preparations

2006
The repressive effect of green tea ingredients on amyloid precursor protein (APP) expression in oral carcinoma cells in vitro and in vivo.
    Cancer letters, 2007, Jan-08, Volume: 245, Issue:1-2

    Topics: Amyloid beta-Protein Precursor; Animals; Blotting, Western; Carcinoma, Squamous Cell; Catechin; Cell Line, Tumor; Cricetinae; Disease Models, Animal; Dose-Response Relationship, Drug; Gene Expression Regulation, Neoplastic; Humans; Immunohistochemistry; Male; Mesocricetus; Mouth Mucosa; Mouth Neoplasms; Phytotherapy; Plant Preparations; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tea

2007
Epigallocatechin-3-gallate protects toluene diisocyanate-induced airway inflammation in a murine model of asthma.
    FEBS letters, 2006, Mar-20, Volume: 580, Issue:7

    Topics: Animals; Asthma; Bronchoalveolar Lavage Fluid; Catechin; Disease Models, Animal; Gene Expression Regulation; Inflammation; Interleukin-5; Matrix Metalloproteinase 9; Mice; Reactive Oxygen Species; Respiratory System; Toluene 2,4-Diisocyanate; Tumor Necrosis Factor-alpha

2006
Epigallocatechin-3-gallate reduces allergen-induced asthma-like reaction in sensitized guinea pigs.
    The Journal of pharmacology and experimental therapeutics, 2006, Volume: 317, Issue:3

    Topics: Allergens; Animals; Anti-Asthmatic Agents; Asthma; Bronchoalveolar Lavage Fluid; Catechin; Disease Models, Animal; Guinea Pigs; Lung; Male; Nitric Oxide Synthase; Ovalbumin

2006
Anti-inflammatory and anti-atherogenic effects of cathechin, caffeic acid and trans-resveratrol in apolipoprotein E deficient mice.
    Atherosclerosis, 2007, Volume: 191, Issue:2

    Topics: Animals; Anti-Inflammatory Agents; Aorta; Apolipoproteins E; Atherosclerosis; Caffeic Acids; Cardiovascular Agents; Catechin; Cytokines; Dietary Fats; Disease Models, Animal; Dose-Response Relationship, Drug; Endothelin-1; Gene Expression; Mice; Mice, Knockout; Receptors, Chemokine; RNA, Messenger; Stilbenes

2007
Anxiolytic properties of green tea polyphenol (-)-epigallocatechin gallate (EGCG).
    Brain research, 2006, Sep-19, Volume: 1110, Issue:1

    Topics: Animals; Anti-Anxiety Agents; Anxiety; Avoidance Learning; Behavior, Animal; Carbolines; Catechin; Cells, Cultured; Chlordiazepoxide; Convulsants; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Electric Stimulation; Electroshock; Embryo, Mammalian; gamma-Aminobutyric Acid; Hippocampus; Male; Maze Learning; Membrane Potentials; Mice; Neurons; Patch-Clamp Techniques; Reaction Time

2006
Wine constituents inhibit thrombosis but not atherogenesis in C57BL/6 apolipoprotein E-deficient mice.
    The British journal of nutrition, 2006, Volume: 96, Issue:2

    Topics: Animals; Antioxidants; Aortic Valve Stenosis; Apolipoproteins E; Atherosclerosis; Catechin; Diet; Disease Models, Animal; Eating; Ethanol; Flavonoids; Genetic Predisposition to Disease; Lipids; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Oxidation-Reduction; Phenols; Polyphenols; Thrombosis; Weight Gain; Wine

2006
Polyphenol (-)-epigallocatechin gallate protection from ischemia/reperfusion-induced renal injury in normotensive and hypertensive rats.
    Transplantation proceedings, 2006, Volume: 38, Issue:7

    Topics: Animals; Blood Urea Nitrogen; Catechin; Creatinine; Disease Models, Animal; Flavonoids; Hypertension; Phenols; Polyphenols; Rats; Rats, Inbred SHR; Reference Values; Renal Circulation; Reperfusion Injury

2006
Neuroprotective effects of (-)-epigallocatechin-3-gallate in a transgenic mouse model of amyotrophic lateral sclerosis.
    Neurochemical research, 2006, Volume: 31, Issue:10

    Topics: Amyotrophic Lateral Sclerosis; Animals; Blotting, Western; Caspase 3; Catechin; Disease Models, Animal; Enzyme Activation; Female; Immunohistochemistry; Male; Mice; Mice, Transgenic; Microglia; Motor Neurons; Neuroprotective Agents; NF-kappa B

2006
Chocolate is a powerful ex vivo and in vivo antioxidant, an antiatherosclerotic agent in an animal model, and a significant contributor to antioxidants in the European and American Diets.
    Journal of agricultural and food chemistry, 2006, Oct-18, Volume: 54, Issue:21

    Topics: Adult; Animals; Antioxidants; Atherosclerosis; Cacao; Catechin; Cricetinae; Diet; Disease Models, Animal; Europe; Female; Humans; Lipid Peroxidation; Lipids; Male; Mesocricetus; Middle Aged; Phenols; United States

2006
Protective effects of EGCg or GCg, a green tea catechin epimer, against postischemic myocardial dysfunction in guinea-pig hearts.
    Life sciences, 2007, Feb-20, Volume: 80, Issue:11

    Topics: Animals; Antioxidants; Apoptosis; Calcium; Caspase 3; Catechin; Disease Models, Animal; Electron Spin Resonance Spectroscopy; Female; Guinea Pigs; Heart; Heart Ventricles; In Vitro Techniques; Male; Mitochondria; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Myocardial Reperfusion Injury; Myocardium; Perfusion; Reactive Oxygen Species

2007
Green tea polyphenols reduce autoimmune symptoms in a murine model for human Sjogren's syndrome and protect human salivary acinar cells from TNF-alpha-induced cytotoxicity.
    Autoimmunity, 2007, Volume: 40, Issue:2

    Topics: Animals; Autoimmunity; Catechin; Cell Line; Cell Survival; Disease Models, Animal; Flavonoids; Humans; Imidazoles; Lymphocytes; MAP Kinase Kinase 4; MAP Kinase Kinase Kinases; Mice; Mice, Inbred NOD; p38 Mitogen-Activated Protein Kinases; Phenols; Phosphorylation; Plant Extracts; Polyphenols; Pyridines; Salivary Glands; Sjogren's Syndrome; Tea; Tumor Necrosis Factor-alpha

2007
Nutrient mixture including vitamin C, L-lysine, L-proline, and epigallocatechin is ineffective against tumor growth and metastasis in a syngeneic neuroblastoma model.
    Pediatric blood & cancer, 2008, Volume: 50, Issue:2

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Ascorbic Acid; Catechin; Dietary Supplements; Disease Models, Animal; Female; Liver Neoplasms, Experimental; Lysine; Mice; Mice, Inbred A; Neuroblastoma; Proline

2008
Combined treatment with green tea catechins and sodium nitrite selectively promotes rat forestomach carcinogenesis after initiation with N-methyl-N'- nitro-N-nitrosoguanidine.
    Cancer science, 2007, Volume: 98, Issue:7

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Catechin; Deoxyguanosine; Disease Models, Animal; Epithelial Cells; Hyperplasia; Male; Methylnitronitrosoguanidine; Rats; Rats, Inbred F344; Stomach Neoplasms; Tea

2007
Green tea polyphenol epigallocatechin-3-gallate inhibits oxidative damage and preventive effects on carbon tetrachloride-induced hepatic fibrosis.
    The Journal of nutritional biochemistry, 2007, Volume: 18, Issue:12

    Topics: Animals; Beverages; Carbon Tetrachloride Poisoning; Catechin; Cell Culture Techniques; Disease Models, Animal; Disease Progression; Enzyme Activation; Liver; Liver Cirrhosis; Male; Matrix Metalloproteinase 2; Rats; Rats, Sprague-Dawley; Rats, Wistar

2007
The green tea polyphenol epigallocatechin-3-gallate improves systemic hemodynamics and survival in rodent models of polymicrobial sepsis.
    Shock (Augusta, Ga.), 2007, Volume: 28, Issue:3

    Topics: Animals; Blood Pressure; Catechin; Disease Models, Animal; Gene Expression; Lung; Male; Mice; Mice, Inbred C57BL; NF-kappa B; Nitrates; Nitric Oxide Synthase Type II; Nitrites; Rats; Rats, Sprague-Dawley; Sepsis; Survival Rate

2007
Modulation of infection-induced inflammation and locomotive deficit and longevity in senescence-accelerated mice-prone (SAMP8) model by the oligomerized polyphenol Oligonol.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2007, Volume: 61, Issue:7

    Topics: Aging; Alzheimer Disease; Animals; Behavior, Animal; Catechin; Dietary Supplements; Disease Models, Animal; Eye; Female; Inflammation; Longevity; Male; Mice; Mice, Inbred Strains; Motor Activity; Parasitic Diseases, Animal; Parkinson Disease; Phenols; Survival Rate; Time Factors; Virus Diseases

2007
Neuroprotective effects of quercetin and rutin on spatial memory impairment in an 8-arm radial maze task and neuronal death induced by repeated cerebral ischemia in rats.
    Journal of pharmacological sciences, 2007, Volume: 104, Issue:4

    Topics: Animals; Brain Ischemia; Catechin; Cell Death; Disease Models, Animal; Flavonoids; Hippocampus; Male; Maze Learning; Memory; Neurons; Neuroprotective Agents; Quercetin; Rats; Rats, Wistar; Rutin; Space Perception; Structure-Activity Relationship

2007
Trypanosoma cruzi: in vitro and in vivo antiproliferative effects of epigallocatechin gallate (EGCg).
    Experimental parasitology, 2007, Volume: 117, Issue:2

    Topics: Animals; Antioxidants; Catechin; Chagas Disease; Disease Models, Animal; DNA Fragmentation; Dose-Response Relationship, Drug; Hepatocytes; In Situ Nick-End Labeling; Male; Mice; Mice, Inbred BALB C; Parasitemia; Random Allocation; Trypanocidal Agents; Trypanosoma cruzi

2007
Epigallocatechin gallate attenuates experimental non-alcoholic steatohepatitis induced by high fat diet.
    Journal of gastroenterology and hepatology, 2008, Volume: 23, Issue:8 Pt 2

    Topics: Animals; Antioxidants; Catechin; Diet; Dietary Fats; Disease Models, Animal; Fatty Liver; Liver; Male; Rats; Rats, Sprague-Dawley

2008
Protective effect of (+)-catechin against gastric mucosal injury induced by ischaemia-reperfusion in rats.
    The Journal of pharmacy and pharmacology, 2007, Volume: 59, Issue:8

    Topics: Administration, Oral; Alkaline Phosphatase; Animals; Antioxidants; Catalase; Catechin; Corticosterone; Disease Models, Animal; Flavonoids; Gastric Mucosa; H(+)-K(+)-Exchanging ATPase; Histamine; Lipid Peroxidation; Male; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Stomach Ulcer; Superoxide Dismutase

2007
Therapeutic effect of epigallocatechin-3-gallate in a mouse model of colitis.
    European journal of pharmacology, 2008, Jan-28, Volume: 579, Issue:1-3

    Topics: Animals; Antioxidants; Catechin; Colitis; Cytokines; Disease Models, Animal; Injections, Intraperitoneal; Mice; Mice, Inbred C57BL; Neutrophil Infiltration; NF-kappa B; Peroxidase; Tea; Transcription Factor AP-1; Trinitrobenzenesulfonic Acid

2008
[Protective effect of epigallocatechin-3-gallate on inflammatory bowel disease: experiment with rat models of induced colitis].
    Zhonghua yi xue za zhi, 2007, Nov-13, Volume: 87, Issue:42

    Topics: Animals; Blotting, Western; Catechin; Cyclooxygenase 2; Disease Models, Animal; Gene Expression; Inflammatory Bowel Diseases; Intestinal Mucosa; Random Allocation; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Trinitrobenzenesulfonic Acid

2007
Green tea catechin polyphenols attenuate behavioral and oxidative responses to intermittent hypoxia.
    American journal of respiratory and critical care medicine, 2008, May-15, Volume: 177, Issue:10

    Topics: Animals; Catechin; Cognition; Disease Models, Animal; Hippocampus; Hypoxia; Lipid Peroxidation; Male; Maze Learning; NADPH Oxidases; Oxidative Stress; Plant Extracts; Rats; Rats, Sprague-Dawley; Sleep Apnea Syndromes; Tea

2008
Preventive effect of (-)epigallocatechin-gallate (EGCG) on lysosomal enzymes in heart and subcellular fractions in isoproterenol-induced myocardial infarcted Wistar rats.
    Chemico-biological interactions, 2008, Apr-15, Volume: 172, Issue:3

    Topics: Animals; Cardiovascular Agents; Catechin; Disease Models, Animal; Heart; Isoproterenol; Lysosomes; Male; Myocardial Infarction; Rats; Rats, Wistar; Subcellular Fractions; Time Factors

2008
The beneficial effect of (-)-epigallocatechin-3-gallate in an experimental model of Alzheimer's disease in rat: a behavioral analysis.
    Iranian biomedical journal, 2007, Volume: 11, Issue:4

    Topics: Alzheimer Disease; Animals; Catechin; Disease Models, Animal; Male; Maze Learning; Psychomotor Performance; Rats; Rats, Wistar

2007
Green tea epigallocatechin-3-gallate (EGCG) reduces beta-amyloid mediated cognitive impairment and modulates tau pathology in Alzheimer transgenic mice.
    Brain research, 2008, Jun-12, Volume: 1214

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Analysis of Variance; Animals; Catechin; Cognition Disorders; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Maze Learning; Mice; Mice, Transgenic; Mutation; Neuroprotective Agents; Phosphorylation; tau Proteins

2008
[Effect of silymarin and (+)-cyanidanol-3 on hexachlorobenzene(HCB)-induced porphyria in rats].
    Zeitschrift fur Gastroenterologie, 1982, Volume: 20, Issue:12

    Topics: Animals; Benzopyrans; Catechin; Chlorobenzenes; Disease Models, Animal; Flavonoids; Hexachlorobenzene; Liver Diseases; Porphyrias; Rats; Research Design; Silymarin

1982
Effects of green tea catechins in a rat multi-organ carcinogenesis model.
    Carcinogenesis, 1993, Volume: 14, Issue:8

    Topics: 1,2-Dimethylhydrazine; Adenoma; Animals; Anticarcinogenic Agents; Body Weight; Butylhydroxybutylnitrosamine; Carcinogenicity Tests; Catechin; Cocarcinogenesis; Colonic Neoplasms; Dimethylhydrazines; Disease Models, Animal; Intestinal Neoplasms; Intestine, Small; Kidney Neoplasms; Liver Neoplasms, Experimental; Lung Neoplasms; Male; Models, Biological; Neoplasms, Experimental; Rats; Rats, Inbred F344

1993
Prevention of doxorubicin induced cardiotoxicity by catechin.
    Cancer letters, 1996, Jan-19, Volume: 99, Issue:1

    Topics: Animals; Antibiotics, Antineoplastic; Antioxidants; Catechin; Depression, Chemical; Disease Models, Animal; Doxorubicin; Electrocardiography; Heart Diseases; Male; Microscopy, Electron; Myocardial Contraction; Rats; Rats, Sprague-Dawley

1996
Effect of dietary catechin and vitamin E on aortic fatty streak accumulation in hypercholesterolemic hamsters.
    Atherosclerosis, 1998, Volume: 137, Issue:1

    Topics: Animals; Aorta; Arteriosclerosis; Catechin; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Cricetinae; Diet; Dietary Fats, Unsaturated; Disease Models, Animal; Eating; Growth; Hypercholesterolemia; Male; Olive Oil; Plant Oils; Vitamin E

1998
Protective effect of Japanese green tea extract on gnotobiotic mice infected with an Escherichia coli O157:H7 strain.
    Microbiology and immunology, 1998, Volume: 42, Issue:2

    Topics: Animals; Anti-Bacterial Agents; Catechin; Disease Models, Animal; Escherichia coli Infections; Escherichia coli O157; Female; Male; Mice; Tea

1998
Green tea polyphenols block endotoxin-induced tumor necrosis factor-production and lethality in a murine model.
    The Journal of nutrition, 1998, Volume: 128, Issue:12

    Topics: Administration, Oral; Animals; Anti-Inflammatory Agents; Anticarcinogenic Agents; Catechin; Cell Line; Disease Models, Animal; Down-Regulation; Flavonoids; Gene Expression Regulation; Lipopolysaccharides; Macrophages, Peritoneal; Male; Mice; Mice, Inbred BALB C; NF-kappa B; Phenols; Polymers; Tea; Tumor Necrosis Factor-alpha

1998
Inhibition of urinary bladder tumors induced by N-butyl-N-(4-hydroxybutyl)-nitrosamine in rats by green tea.
    International journal of urology : official journal of the Japanese Urological Association, 1999, Volume: 6, Issue:2

    Topics: Animals; Body Weight; Butylhydroxybutylnitrosamine; Carcinogens; Carcinoma, Squamous Cell; Carcinoma, Transitional Cell; Catechin; Disease Models, Animal; Dose-Response Relationship, Drug; Hyperplasia; Male; Papilloma; Rats; Rats, Wistar; Tea; Urinary Bladder Neoplasms

1999
[Studies on the effects of tea catechins against hepatitis B virus infection].
    Zhonghua yu fang yi xue za zhi [Chinese journal of preventive medicine], 2001, Volume: 35, Issue:6

    Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Catechin; Disease Models, Animal; DNA, Viral; Ducks; Hepatitis B Virus, Duck; Hepatitis, Viral, Animal; Tea

2001
The protective effect of catechin on gastric mucosal lesions in rats, and its hormonal mechanisms.
    Journal of gastroenterology, 2002, Volume: 37, Issue:2

    Topics: Animals; Catechin; Disease Models, Animal; Gastric Mucosa; Gastrins; Male; Rats; Rats, Wistar; Somatostatin; Stomach Diseases

2002
The protective activity of tea catechins against experimental infection by Vibrio cholerae O1.
    Microbiology and immunology, 1992, Volume: 36, Issue:9

    Topics: Animals; Body Fluids; Catechin; Cholera; Cholera Toxin; Disease Models, Animal; Intestines; Male; Mice; Mice, Inbred C57BL; Rabbits; Tea

1992
Protease inhibitors prevent the development of human rotavirus-induced diarrhea in suckling mice.
    Microbiology and immunology, 1991, Volume: 35, Issue:7

    Topics: Administration, Oral; Animals; Animals, Suckling; Aprotinin; Catechin; Cysteine Proteinase Inhibitors; Diarrhea; Disease Models, Animal; Flavonoids; Intestine, Small; Mice; Mice, Inbred BALB C; Protease Inhibitors; Rotavirus; Rotavirus Infections; Serine Proteinase Inhibitors

1991